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CDC Zika Pregnancy Registry


niman

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On May 20 the CDC announced the reporting of asymptomatic pregnant women in the United States and territories with laboratory evidence of Zika infection, including IgM without PRINT confirmation.  The initial MMWR cited 157 pregnant cases in the United States with laboratory evidence of Zika infection, with an additional 122 in US territories, for a total of 279 cases.

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Possible Zika Virus Infection Among Pregnant Women — United States and Territories, May 2016

Regina M. Simeone, MPH1; Carrie K. Shapiro-Mendoza, PhD2; Dana Meaney-Delman, MD3; Emily E. Petersen, MD2; Romeo R. Galang, MD4,5; Titilope Oduyebo, MD2,4; Brenda Rivera-Garcia, DVM6; Miguel Valencia-Prado, MD7; Kimberly B. Newsome, MPH1; Janice Pérez-Padilla, MPH8; Tonya R. Williams, PhD9; Matthew Biggerstaff, MPH10; Denise J. Jamieson, MD2; Margaret A. Honein, PhD1; Zika and Pregnancy Working Group 

http://www.cdc.gov/mmwr/volumes/65/wr/mm6520e1.htm?s_cid=mm6520e1_w

 

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Summary

What is already known about this topic?

Zika virus infection during pregnancy causes microcephaly and other serious brain abnormalities. However, the full range of outcomes of asymptomatic and symptomatic Zika virus infection during pregnancy are not yet well understood.

What is added by this report?

In February 2016, CDC, in collaboration with state, local, tribal, and territorial health departments, launched comprehensive surveillance systems to report and actively monitor pregnancies and congenital outcomes among symptomatic and asymptomatic women with laboratory evidence of possible Zika virus infection. As of May 12, 2016, there were 157 and 122 pregnant women with laboratory evidence of possible Zika virus infection residing in U.S. states and U.S. territories, respectively.

What are the implications for public health practice?

This report launches the weekly reporting of pregnant women with laboratory evidence of possible Zika virus infection in U.S. states and territories. Monitoring all pregnant women with possible Zika virus infection during pregnancy, whether asymptomatic or symptomatic, will enhance understanding of possible adverse outcomes and allow better estimates of the number of pregnancies at risk for adverse outcomes. This information will assist health care providers who counsel pregnant women and will facilitate planning services for affected families.

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Pregnant Women with Any Laboratory Evidence of Possible Zika Virus Infection in the United States and Territories, 2016

 

Pregnant Women with Any Laboratory Evidence of Possible Zika Virus Infection

US States and the District of Columbia

  • Pregnant women with any laboratory evidence of possible Zika virus infection: 157*

*This update includes aggregated data reported to the US Zika Pregnancy Registry as of May 12, 2016.

US Territories

  • Pregnant women with any laboratory evidence of possible Zika virus infection: 122*

*This update includes data from the US territories reported to the US Zika Pregnancy Registry and data from Puerto Rico reported to the Zika Active Pregnancy Surveillance System as of May 12, 2016.

About These Numbers

What these updated numbers show

  • These updated numbers reflect counts of pregnant women in the United States with any laboratory evidence of possible Zika virus infection, with or without symptoms. Pregnant women with laboratory evidence include those in whom viral particles have been detected and those with evidence of an immune reaction to a recent virus that is likely to be Zika.
  • This information will help healthcare providers as they counsel pregnant women affected by Zika and is essential for planning at the federal, state, and local levels for clinical, public health, and other services needed to support pregnant women and families affected by Zika.

What these new numbers do not show

  • These new numbers are not comparable to the previous reports. These updated numbers reflect a different, broader population of pregnant women.
  • These updated numbers are not real time estimates. They will reflect the number of pregnant women reported with any laboratory evidence of possible Zika virus infection as of 12 noon every Thursday the week prior; numbers will be delayed one week.

Where do these numbers come from?

These data reflect pregnant women in the US Zika Pregnancy Registry and the Zika Active Pregnancy Surveillance System in Puerto Rico. CDC, in collaboration with state, local, tribal and territorial health departments, established these registries for comprehensive monitoring of pregnancy and infant outcomes following Zika virus infection.  

The data collected through these registries will be used to update recommendations for clinical care, to plan for services and support for pregnant women and families affected by Zika virus, and to improve prevention of Zika virus infection during pregnancy.

http://www.cdc.gov/zika/geo/pregwomen-uscases.html

 

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Pregnant Women with Any Laboratory Evidence of Possible Zika Virus Infection

US States and the District of Columbia

  • Pregnant women with any laboratory evidence of possible Zika virus infection: 168*

*This update includes aggregated data reported to the US Zika Pregnancy Registry as of May 26, 2016.

US Territories

  • Pregnant women with any laboratory evidence of possible Zika virus infection: 142*

*This update includes data from the US territories reported to the US Zika Pregnancy Registry and data from Puerto Rico reported to the Zika Active Pregnancy Surveillance System as of May 26, 2016.

About These Numbers

What these updated numbers show

  • These updated numbers reflect counts of pregnant women in the United States with any laboratory evidence of possible Zika virus infection, with or without symptoms. Pregnant women with laboratory evidence include those in whom viral particles have been detected and those with evidence of an immune reaction to a recent virus that is likely to be Zika.
  • This information will help healthcare providers as they counsel pregnant women affected by Zika and is essential for planning at the federal, state, and local levels for clinical, public health, and other services needed to support pregnant women and families affected by Zika.

What these new numbers do not show

  • These new numbers are not comparable to the previous reports. These updated numbers reflect a different, broader population of pregnant women.
  • These updated numbers are not real time estimates. They will reflect the number of pregnant women reported with any laboratory evidence of possible Zika virus infection as of 12 noon every Thursday the week prior; numbers will be delayed one week.

Where do these numbers come from?

These data reflect pregnant women in the US Zika Pregnancy Registry and the Zika Active Pregnancy Surveillance System in Puerto Rico. CDC, in collaboration with state, local, tribal and territorial health departments, established these registries for comprehensive monitoring of pregnancy and infant outcomes following Zika virus infection.  

The data collected through these registries will be used to update recommendations for clinical care, to plan for services and support for pregnant women and families affected by Zika virus, and to improve prevention of Zika virus infection during pregnancy.

 
 
 
  • Page last reviewed: May 20, 2016
  • Page last updated: May 26, 2016
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Pregnant Women with Any Laboratory Evidence of Possible Zika Virus Infection

US States and the District of Columbia

  • Pregnant women with any laboratory evidence of possible Zika virus infection: 195*

*This update includes aggregated data reported to the US Zika Pregnancy Registry as of May 26, 2016.

US Territories

  • Pregnant women with any laboratory evidence of possible Zika virus infection: 146*

*This update includes data from the US territories reported to the US Zika Pregnancy Registry and data from Puerto Rico reported to the Zika Active Pregnancy Surveillance System as of May 26, 2016.

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Pregnant Women with Any Laboratory Evidence of Possible Zika Virus Infection

US States and the District of Columbia

  • Pregnant women with any laboratory evidence of possible Zika virus infection: 206*

*This update includes aggregated data reported to the US Zika Pregnancy Registry as of June 2, 2016.

US Territories

  • Pregnant women with any laboratory evidence of possible Zika virus infection: 166*

*This update includes data from the US territories reported to the US Zika Pregnancy Registry and data from Puerto Rico reported to the Zika Active Pregnancy Surveillance System as of June 2, 2016.

About These Numbers

What these updated numbers show

  • These updated numbers reflect counts of pregnant women in the United States with any laboratory evidence of possible Zika virus infection, with or without symptoms. Pregnant women with laboratory evidence include those in whom viral particles have been detected and those with evidence of an immune reaction to a recent virus that is likely to be Zika.
  • This information will help healthcare providers as they counsel pregnant women affected by Zika and is essential for planning at the federal, state, and local levels for clinical, public health, and other services needed to support pregnant women and families affected by Zika.

What these new numbers do not show

  • These new numbers are not comparable to the previous reports. These updated numbers reflect a different, broader population of pregnant women.
  • These updated numbers are not real time estimates. They will reflect the number of pregnant women reported with any laboratory evidence of possible Zika virus infection as of 12 noon every Thursday the week prior; numbers will be delayed one week.

Where do these numbers come from?

These data reflect pregnant women in the US Zika Pregnancy Registry and the Zika Active Pregnancy Surveillance System in Puerto Rico. CDC, in collaboration with state, local, tribal and territorial health departments, established these registries for comprehensive monitoring of pregnancy and infant outcomes following Zika virus infection.  

The data collected through these registries will be used to update recommendations for clinical care, to plan for services and support for pregnant women and families affected by Zika virus, and to improve prevention of Zika virus infection during pregnancy.

 
 
 
  • Page last reviewed: May 20, 2016
  • Page last updated: June 9, 2016
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Pregnant Women with Any Laboratory Evidence of Possible Zika Virus Infection in the United States and Territories, 2016

 

Pregnant Women with Any Laboratory Evidence of Possible Zika Virus Infection

US States and the District of Columbia*

234

*Includes aggregated data reported to the US Zika Pregnancy Registry as of June 9, 2016

US Territories**

189

**Includes aggregated data from the US territories reported to the US Zika Pregnancy Registry and data from Puerto Rico reported to the Zika Active Pregnancy Surveillance System as of June 9, 2016

 

About These Numbers

What these updated numbers show

  • These updated numbers reflect counts of pregnant women in the United States with any laboratory evidence of possible Zika virus infection, with or without symptoms. Pregnant women with laboratory evidence include those in whom viral particles have been detected and those with evidence of an immune reaction to a recent virus that is likely to be Zika.
  • This information will help healthcare providers as they counsel pregnant women affected by Zika and is essential for planning at the federal, state, and local levels for clinical, public health, and other services needed to support pregnant women and families affected by Zika.

What these new numbers do not show

  • These new numbers are not comparable to the previous reports. These updated numbers reflect a different, broader population of pregnant women.
  • These updated numbers are not real time estimates. They will reflect the number of pregnant women reported with any laboratory evidence of possible Zika virus infection as of 12 noon every Thursday the week prior; numbers will be delayed one week.

Where do these numbers come from?

These data reflect pregnant women in the US Zika Pregnancy Registry and the Zika Active Pregnancy Surveillance System in Puerto Rico. CDC, in collaboration with state, local, tribal and territorial health departments, established these registries for comprehensive monitoring of pregnancy and infant outcomes following Zika virus infection.  

The data collected through these registries will be used to update recommendations for clinical care, to plan for services and support for pregnant women and families affected by Zika virus, and to improve prevention of Zika virus infection during pregnancy.

What are the outcomes for these pregnancies?

Visit CDC’s webpage for updated counts of poor pregnancy outcomes related to Zika. Most of the pregnancies monitored by these systems are ongoing. CDC will not report outcomes until pregnancies are complete.

 
 
 
  • Page last reviewed: May 20, 2016
  • Page last updated: June 15, 2016
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Pregnant Women with Any Laboratory Evidence of Possible Zika Virus Infection in the United States and Territories, 2016

 

Pregnant Women with Any Laboratory Evidence of Possible Zika Virus Infection

US States and the District of Columbia*

265

*Includes aggregated data reported to the US Zika Pregnancy Registry as of June 16, 2016

US Territories**

216

**Includes aggregated data from the US territories reported to the US Zika Pregnancy Registry and data from Puerto Rico reported to the Zika Active Pregnancy Surveillance System as of June 16, 2016

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US States and the District of Columbia*

287

*Includes aggregated data reported to the US Zika Pregnancy Registry as of June 23, 2016

US Territories**

250

**Includes aggregated data from the US territories reported to the US Zika Pregnancy Registry and data from Puerto Rico reported to the Zika Active Pregnancy Surveillance System as of June 23, 2016

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Pregnant Women with Any Laboratory Evidence of Possible Zika Virus Infection

US States and the District of Columbia*

320

*Includes aggregated data reported to the US Zika Pregnancy Registry as of June 30, 2016

US Territories**

279

**Includes aggregated data from the US territories reported to the US Zika Pregnancy Registry and data from Puerto Rico reported to the Zika Active Pregnancy Surveillance System as of June 30, 2016

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Pregnant Women with Any Laboratory Evidence of Possible Zika Virus Infection

US States and the District of Columbia*

346

*Includes aggregated data reported to the US Zika Pregnancy Registry as of July 7, 2016

US Territories**

303

**Includes aggregated data from the US territories reported to the US Zika Pregnancy Registry and data from Puerto Rico reported to the Zika Active Pregnancy Surveillance System as of July 7, 2016

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Pregnant Women with Any Laboratory Evidence of Possible Zika Virus Infection in the United States and Territories, 2016

 

Pregnant Women with Any Laboratory Evidence of Possible Zika Virus Infection

US States and the District of Columbia*

400

*Includes aggregated data reported to the US Zika Pregnancy Registry as of July 14, 2016

US Territories**

378

**Includes aggregated data from the US territories reported to the US Zika Pregnancy Registry and data from Puerto Rico reported to the Zika Active Pregnancy Surveillance System as of July 14, 2016

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Pregnant Women with Any Laboratory Evidence of Possible Zika Virus Infection

US States and the District of Columbia*

433

*Includes aggregated data reported to the US Zika Pregnancy Registry as of July 21, 2016

US Territories**

422

**Includes aggregated data from the US territories reported to the US Zika Pregnancy Registry and data from Puerto Rico reported to the Zika Active Pregnancy Surveillance System as of July 21, 2016

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Pregnant Women with Any Laboratory Evidence of Possible Zika Virus Infection

US States and the District of Columbia*

479

*Includes aggregated data reported to the US Zika Pregnancy Registry as of July 28, 2016

US Territories**

493

**Includes aggregated data from the US territories reported to the US Zika Pregnancy Registry and data from Puerto Rico reported to the Zika Active Pregnancy Surveillance System as of July 28, 2016

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  • 2 weeks later...

Pregnant Women with Any Laboratory Evidence of Possible Zika Virus Infection

US States and the District of Columbia*

529

*Includes aggregated data reported to the US Zika Pregnancy Registry as of August 11, 2016

US Territories**

691

**Includes aggregated data from the US territories reported to the US Zika Pregnancy Registry and data from Puerto Rico reported to the Zika Active Pregnancy Surveillance System as of August 11, 2016

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US States and the District of Columbia*

584

*Includes aggregated data reported to the US Zika Pregnancy Registry as of August 18, 2016

US Territories**

812

**Includes aggregated data from the US territories reported to the US Zika Pregnancy Registry and data from Puerto Rico reported to the Zika Active Pregnancy Surveillance System as of August 18, 2016

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Pregnant Women with Any Laboratory Evidence of Possible Zika Virus Infection

US States and the District of Columbia*

624

*Includes aggregated data reported to the US Zika Pregnancy Registry as of August 25, 2016

US Territories**

971

**Includes aggregated data from the US territories reported to the US Zika Pregnancy Registry and data from Puerto Rico reported to the Zika Active Pregnancy Surveillance System as of August 25, 2016

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regnant Women with Any Laboratory Evidence of Possible Zika Virus Infection

US States and the District of Columbia*

671

*Includes aggregated data reported to the US Zika Pregnancy Registry as of September 1, 2016

US Territories**

1,080

**Includes aggregated data from the US territories reported to the US Zika Pregnancy Registry and data from Puerto Rico reported to the Zika Active Pregnancy Surveillance System as of September 1, 2016

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Pregnant Women with Any Laboratory Evidence of Possible Zika Virus Infection

US States and the District of Columbia*

731

*Includes aggregated data reported to the US Zika Pregnancy Registry as of September 8, 2016

US Territories**

1,156

**Includes aggregated data from the US territories reported to the US Zika Pregnancy Registry and data from Puerto Rico reported to the Zika Active Pregnancy Surveillance System as of September 8, 2016

 

About These Numbers

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Pregnant Women with Any Laboratory Evidence of Possible Zika Virus Infection

US States and the District of Columbia*

749

*Includes aggregated data reported to the US Zika Pregnancy Registry as of September 15, 2016

US Territories**

1,348

**Includes aggregated data from the US territories reported to the US Zika Pregnancy Registry and data from Puerto Rico reported to the Zika Active Pregnancy Surveillance System as of September 15, 2016

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  • 2 weeks later...

Pregnant Women with Any Laboratory Evidence of Possible Zika Virus Infection

US States and the District of Columbia*

808

*Includes aggregated data reported to the US Zika Pregnancy Registry as of September 22, 2016

US Territories**

1,490

**Includes aggregated data from the US territories reported to the US Zika Pregnancy Registry and data from Puerto Rico reported to the Zika Active Pregnancy Surveillance System as of September 22, 2016

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Pregnant Women with Any Laboratory Evidence of Possible Zika Virus Infection

US States and the District of Columbia*

837

*Includes aggregated data reported to the US Zika Pregnancy Registry as of September 29, 2016

US Territories**

1,638

**Includes aggregated data from the US territories reported to the US Zika Pregnancy Registry and data from Puerto Rico reported to the Zika Active Pregnancy Surveillance System as of September 29, 2016

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Pregnant Women with Any Laboratory Evidence of Possible Zika Virus Infection

US States and the District of Columbia*

878

*Includes aggregated data reported to the US Zika Pregnancy Registry as of October 6, 2016

US Territories**

1,806

**Includes aggregated data from the US territories reported to the US Zika Pregnancy Registry and data from Puerto Rico reported to the Zika Active Pregnancy Surveillance System as of October 6, 2016

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