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H3N2v Case In New Jersey - No Direct Swine Contact

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CDC's week 52 FluView cites first H3N2v case in New Jersey -no direct swine contact.

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Novel Influenza A Virus:

One human infection with a novel influenza A virus was reported by the state of New Jersey. The person was infected with an influenza A (H3N2) variant (H3N2v) virus. The patient was not hospitalized and has fully recovered from their illness. The patient visited a farm near where swine are frequently housed but no direct contact with swine was reported in the week prior to illness onset. No ongoing human-to-human transmission has been identified.

Early identification and investigation of human infections with novel influenza A viruses are critical so that the risk of infection can be more fully appreciated and appropriate public health measures can be taken. Additional information on influenza in swine, variant influenza infection in humans, and strategies to interact safely with swine can be found at http://www.cdc.gov/flu/swineflu/index.htm.

http://www.cdc.gov/flu/weekly/

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Case Count: Detected U.S. Human Infections with H3N2v by State since August 2011

Table 1. Case Count: Detected U.S. Human Infections with H3N2v by State since August 2011

States Reporting H3N2v CasesCases in
2011
Cases in
2012
Cases in
2013
Cases in
2014
Cases in
2015

Hawaii

 1   

Illinois

 41  

Indiana

213814  

Iowa

311  

Maine

2    

Maryland

 12   

Michigan

 62 1

Minnesota

 5  1

Ohio

 10712 

Pennsylvania

311   

Utah

 1*   

West Virginia

23   

Wisconsin

 20 1 

Total

123091932

* Case in Utah occurred in April 2012.

This chart indicates the number of CDC-reported infections with H3N2v variant influenza A viruses since August 2011 and is current as of September 4, 2015. This case count will be updated each Friday as new cases are reported.

NOTE: The state totals reported by CDC may not always be consistent with those reported by state health departments. If there is a discrepancy between these two counts, data from the state health departments should be used as the most accurate number.

Table 2. H3N2v Hospitalizations and Deaths Since July 2012*

H3N2v Hospitalizations and Deaths Since July 2012Cases in
2012
Cases in
2013
Cases in
2014
Cases in
2015

Hospitalizations

16112

Deaths

1000

* As reported by states to CDC. This chart indicates the number of CDC-reported infections with H3N2v variant influenza A viruses since July 2012 and is current as of September 4, 2015. This case count will be not be updated again until new cases are reported.

See Reported Infections with Variant Influenza Viruses in the United States since 2005 for a complete list of human infections with all variant viruses since 2005.

 

http://www.cdc.gov/flu/swineflu/h3n2v-case-count.htm

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CDC has released sequence for 6 segments,and the N2 traces back to seasonal flu in the 1990's,in contrast to to recent human H3N2v cases which trace back to seasonal flu from 2003.

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Isolate detail
Isolate name:
 
A/New Jersey/53/2015 
 
 
Isolate ID:
 
EPI_ISL_205586 
 
 
Passage details/history:
 
OR 
 
 
Type:
 
A / H3N2 
 
 
Lineage:
 
 
Sample information

 

Collection date:
 
2015-12-26 
 
 
Host
 
Human 
 
 
Additional host information:
 
 
 
 
Zip code:
 
 
 
 
Patient status:
 
 
 
 
Last vaccinated:
 
 
 
 
In-vivo pathogenicity test:
 
 
 
 
Location:
 
United States / New Jersey 
 
 
Additional location information:
 
 
 
 
Patient age:
 
 
 
 
Gender:
 
 
 
 
Outbreak:
 
 
 
 
Treatment:
 
 
 
 
Specimen source:
 
 
 
 
Institute information

 

Originating lab:
 
New Jersey Department of Health & Senior Services
 
Sample ID given by the sample provider:
 
15-1622 ORIGINAL 
 
 
Address:
 
New Jersey Department of Health & Senior Services
 369 S Warren St Health & Agriculture Bldg
Trenton,  08625-0361
United States
 
Submitting lab:
 
Centers for Disease Control and Prevention
 
Sample ID given by the submitting laboratory:
 
3000411568 
 
 
Authors:
 
 
 
Address:
 
Centers for Disease Control and Prevention
WHO Collaborating Center for Surveillance, Epidemiology and Control of Influenza, Influenza Division
 1600 Clifton Road, N.E.
Atlanta, GA 30333
United States
 
Publication
Publication
 
In vivo antiviral resistance

 

Antiviral resistance tested by experimental procedures
 
Adamantanes:
 
Unknown 
 
 
Oseltamivir:
 
Unknown 
 
 
Zanamivir:
 
Unknown 
 
 
Peramivir:
 
Unknown 
 
 
Other:
 
Unknown 
 
 
Additional information
Antigenic characterization:
 
 
 
 
Note:
 
 
 
 
Sequence

 

segmentidentifierlengthaccession #INSDCSequence
 
PB2
 
3000411568_283434_v1_1
 
2286
 
EPI685731
 
 
 
 
PA
 
3000411568_283434_v1_3
 
2227
 
EPI685730
 
 
 
 
HA
 
3000411568_283434_v1_4
 
1737
 
EPI685734
 
 
 
 
NP
 
3000411568_283434_v1_5
 
1552
 
EPI685727
 
 
 
 
NA
 
3000411568_283434_v1_6
 
1391
 
EPI685733
 
 
 
 
MP
 
3000411568_283434_v1_7
 
977
 
EPI685729
 
 
 
Submitter information

 

Submitter:
 
Jang, Yunho  
 
 
Submission Date:
 
2016-01-11 
 
 
Last modifier:
 
Jang, Yunho  
 
 
Last modified:
 
2016-01-15 
 
 
Address:
 
Centers for Disease Control and Prevention
WHO Collaborating Center for Surveillance, Epidemiology and Control of Influenza, Influenza Division
 1600 Clifton Road, N.E.
Atlanta, GA 30333
United States

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