niman Posted February 5, 2016 Report Posted February 5, 2016 CDC has released a full Zika sequence from November 2015 Guatemala outbreakhttp://www.ncbi.nlm.nih.gov/nuccore/KU501217.1
niman Posted February 5, 2016 Author Report Posted February 5, 2016 LOCUS KU501217 10272 bp RNA linear VRL 01-FEB-2016 DEFINITION Zika virus strain 8375 polyprotein gene, complete cds. ACCESSION KU501217 VERSION KU501217.1 GI:984874585 KEYWORDS . SOURCE Zika virus ORGANISM Zika virus Viruses; ssRNA viruses; ssRNA positive-strand viruses, no DNA stage; Flaviviridae; Flavivirus; Spondweni virus group. REFERENCE 1 (bases 1 to 10272) AUTHORS Lanciotti,R.S., Lambert,A.J., Holodniy,M., Saavedra,S. and del Carmen Castillo Signor,L. TITLE Phylogeny of Zika Virus in Western Hemisphere, 2015 JOURNAL Emerging Infect. Dis. (2016) In press REMARK Publication Status: Available-Online prior to print DOI: 10.3201/eid2205.160065 REFERENCE 2 (bases 1 to 10272) AUTHORS Lanciotti,R.S. and del Carmen Castillo Signor,L. TITLE Direct Submission JOURNAL Submitted (06-JAN-2016) Diagnostic & Reference Laboratory, Arbovirus Diseases Branch, Centers for Disease Control & Prevention, 3150 Rampart Road, Fort Collins, CO 80521, USA COMMENT ##Assembly-Data-START## Assembly Method :: CLC Genomics Workbench v. V7 Sequencing Technology :: IonTorrent ##Assembly-Data-END## FEATURES Location/Qualifiers source 1..10272 /organism="Zika virus" /mol_type="genomic RNA" /strain="8375" /host="Homo sapiens" /db_xref="taxon:64320" /country="Guatemala" /collection_date="01-Nov-2015" CDS 1..10272 /note="C-prM/M-E-NS1-NS2a-NS2b-NS3-NS4A-NS4B-NS5" /codon_start=1 /product="polyprotein" /protein_id="AMC13913.1" /db_xref="GI:984874586" /translation="MKNPKKKSGGFRIVNMLKRGVARVSPFGGLKRLPAGLLLGHGPI RMVLAILAFLRFTAIKPSLGLINRWGSVGKKEAMEIIKKFKKDLAAMLRIINARKEKK RRGADTSVGIVGLLLTTAMAAEVTRRGSAYYMYLDRNDAGEAISFPTTLGMNKCYIQI MDLGHMCDATMSYECPMLDEGVEPDDVDCWCNTTSTWVVYGTCHHKKGEARRSRRAVT LPSHSTRKLQTRSQTWLESREYTKHLIRVENWIFRNPGFALAAAAIAWLLGSSTSQKV IYLVMILLIAPAYSIRCIGVSNRDFVEGMSGGTWVDVVLEHGGCVTVMAQDKPTVDIE LVTTTVSNMAEIRSYCYEASISDMASDSRCPTQGEAYLDKQSDTQYVCKRTLVDRGWG NGCGLFGKGSLVTCAKFACSKKMTGKSIQPENLEYRIMLSVHGSQHSGMIVNDTGHET DENRAKVEITPNSPRAEATLGGFGSLGLDCEPRTGLDFSDLYYLTMNNKHWLVHKEWF HDIPLPWHAGADTGTPHWNNKEALVEFKDAHAKRQTVVVLGSQEGAVHTALAGALEAE MDGAKGRLSSGHLKCRLKMDKLRLKGVSYSLCTAAFTFTKIPAETLHGTVTVEVQYAG TDGPCKVPAQMAVDMQTLTPVGRLITANPVITESTENSKMMLELDPPFGDSYIVIGVG EKKITHHWHRSGSTIGKAFEATVRGAKRMAVLGDTAWDFGSVGGALNSLGKGIHQIFG AAFKSLFGGMSWFSQILIGTLLMWLGLNTKNGSISLMCLALGGVLIFLSTAVSADVGC SVDFSKKETRCGTGVFVYNDVEAWRDRYKYHPDSPRRLAAAVKQAWEDGICGISSVSR MENIMWRSVEGELNAILEENGVQLTVVVGSVKNPMWRAPQRLPVPVNELPHGWKAWGK SYFVRAAKTNNSFVVDGDTLKECPLKHRAWNSFLVEDHGFGVFHTSVWLKVREDYSLE CDPAVIGTAVKGKEAVHSDLGYWIESEKNDTWRLKRAHLIEMKTCEWPKSHTLWTDGI EESDLIIPKSLAGPLSHHNTREGYRTQMKGPWHSEELEIRFEECPGTKVHVEETCGTR GPSLRSTTASGRVIEEWCCRECTMPPLSFRAKDGCWYGMEIRPRKEPESNLVRSMVTA GSTDHMDHFSLGVLVILLMVQEGLKKRMTTKIIISTSMAVLVAMILGGFSMSDLAKLA ILMGATFAEMNTGGDVAHLALIAAFKVRPALLVSFIFRANWTPRESMLLALASCLLQT AISALEGDLMVLINGFALAWLAIRAMVVPRTDNITLAILAALTPLARGTLLVAWRAGL ATCGGFMLLSLKGKGSVKKNLPFVMALGLTAVRLVDPINVVGLLLLTRSGKRSWPPSE VLTAVGLICALAGGFAKADIEMAGPMAAVGLLIVSYVVSGKSVDMYIERAGDITWEKD AEVTGNSPRLDVALDESGDFSLVEDDGPPMREIILKVVLMTICGMNPIAIPFAAGAWY VYVKTGKRSGALWDVPAPKEVKKGETTDGVYRVMTRRLLGSTQVGVGVMQEGVFHTMW HVTKGSALRSGEGRLDPYWGDVKQDLVSYCGPWKLDAAWDGHSEVQLLAVPPGERARN IQTLPGIFKTKDGDIGAVALDYPAGTSGSPILDKCGRVIGLYGNGVVIKNGSYVSAIT QGRREEETPVECFEPSMLKKKQLTVLDLHPGAGKTRRVLPEIVREAIKTRLRTVILAP TRVVAAEMEEALRGLPVRYMTTAVNVTHSGTEIVDLMCHATFTSRLLQPIRVPNYNLY IMDEAHFTDPSSIAARGYISTRVEMGEAAAIFMTATPPGTRDAFPDSNSPIMDTEVEV PERAWSSGFDWVTDHSGKTVWFVPSVRNGNEIAACLTKAGKRVIQLSRKTFETEFQKT KHQEWDFVVTTDISEMGANFKADRVIDSRRCLKPVILDGERVILAGPMPVTHASAAQR RGRIGRNPNKPGDEYLYGGGCAETDEDHAHWLEARMLLDNIYLQDGLIASLYRPEADK VAAIEGEFKLRTEQRKTFVELMKRGDLPVWLAYQVASAGITYTDRRWCFDGTTNNTIL EDSVPAEVWTRHGEKRVLKPRWMDARVCSDHAALKSFKEFAAGKRGAAFGVMEALGTL PGHMTERFQEAIDNLAVLMRAETGSRPYKAAAAQLPETLETIMLLGLLGTVSLGIFFV LMRNKGIGKMGFGMVTLGASAWLMWLSEIEPARIACVLIVVFLLLVVLIPEPEKQRSP QDNQMAIIIMVAVGLLGLITANELGWLERTKSDLSHLMGRREEGATIGFSMDIDLRPA SAWAIYAALTTFITPAVQHAVTTSYNNYSLMAMATQAGVLFGMGKGMPFYAWDFGVPL LMIGCYSQLTPLTLIVAIILLVAHYMYLIPGLQAAAARAAQKRTAAGIMKNPVVDGIV VTDIDTMTIDPQVEKKMGQVLLIAVAVSSAILSRTAWGWGEAGALITAATSTLWEGSP NKYWNSSTATSLCNIFRGSYLAGASLIYTVTRNAGLVKRRGGGTGETLGEKWKARLNQ MSALEFYSYKKSGITEVCREEARRALKDGVATGGHAVSRGSAKLRWLVERGYLQPYGK VIDLGCGRGGWSYYAATIRKVQEVKGYTKGGPGHEEPVLVQSYGWNIVRLKSGVDVFH MAAEPCDTLLCDIGESSSSPEVEEARTLRVLSMVGDWLERRPGAFCIKVLCPYTSTMM ETLERLQRRYGGGLVRVPLSRNSTHEMYWVSGAKSNTIKSVSTTSQLLLGRMDGPRRP VKYEEDVNLGSGTRAVVSCAEAPNMKIIGNRIERIRSEHAETWFFDENHPYRTWAYHG SYEAPTQGSASSLINGVVRLLSKPWDVVTGVTGIAMTDTTPYGQQRVFKEKVDTRVPD PQEGTRQVMSMVSSWLWKELGKHKRPRVCTKEEFINKVRSNAALGAIFEEEKEWKTAV EAVNDPRFWALVDKEREHHLRGECQSCVYNMMGKREKKQGEFGKAKGSRAIWYMWLGA RFLEFEALGFLNEDHWMGRENSGGGVEGLGLQRLGYVLEEMSCIPGGRMYADDTAGWD TRISRFDLENEALITNQMEKGHRALALAIIKYTYQNKVVKVLRPAEKGKTVMDIISRQ DQRGSGQVVTYALNTFTNLVVQLIRNMEAEEVLEMQDLWLLRRSEKVTNWLQSNGWDR LKRMAVSGDDCVVKPIDDRFAHALRFLNDMGKVRKDTQEWKPSTGWDNWEEVPFCSHH FNKLHLKDGRSIVVPCRHQDELIGRARVSPGAGWSIRETACLAKSYAQMWQLLYFHRR DLRLMANAICSSVPVDWVPTGRTTWSIHGKGEWMTTEDMLVVWNRVWIEENDHMEDKT PVTKWTDIPYLGKREDLWCGSLIGHRPRTTWAENIKNTVNMVRRIIGDEEKYMDYLST QVRYLGEEGSTPGVL" ORIGIN 1 atgaaaaacc caaaaaagaa atccggagga ttccggattg tcaatatgct aaaacgcgga 61 gtagcccgtg tgagcccctt tgggggcttg aagaggctgc cagccggact tctgctgggt 121 catgggccca tcaggatggt cttggcgatt ctagcctttt tgagattcac ggcaatcaag 181 ccatcactgg gtctcatcaa tagatggggt tcagtgggga aaaaagaggc tatggaaata 241 ataaagaagt tcaagaaaga tctggctgcc atgctgagaa taatcaatgc taggaaggag 301 aagaagagac gaggcgcaga tactagtgtc ggaattgttg gcctcctgct gaccacagct 361 atggcagcgg aggtcactag acgtgggagt gcatactata tgtacttgga cagaaacgat 421 gctggggagg ccatatcttt tccaaccaca ttggggatga ataagtgtta tatacagatc 481 atggatcttg gacacatgtg tgatgccacc atgagctatg aatgccctat gctggatgag 541 ggggtggaac cagatgacgt cgattgttgg tgcaacacga cgtcaacttg ggttgtgtac 601 ggaacctgcc atcacaaaaa aggtgaagca cggagatcta gaagagctgt gacgctcccc 661 tcccattcca ctaggaagct gcaaacgcgg tcgcaaacct ggttggaatc aagagaatac 721 acaaagcact tgattagagt cgaaaattgg atattcagga accctggctt cgcgttagca 781 gcagctgcca tcgcttggct tttgggaagc tcaacgagcc aaaaagtcat atacttggtc 841 atgatactgc tgattgcccc ggcatacagc atcaggtgca taggagtcag caatagggac 901 tttgtggaag gtatgtcagg tgggacttgg gttgatgttg tcttggaaca tggaggttgt 961 gtcaccgtaa tggcacagga caaaccgact gtcgacatag agctggttac aacaacagtc 1021 agcaacatgg cggagataag atcctactgc tatgaggcat caatatcaga catggcttcg 1081 gacagccgct gcccaacaca aggtgaagcc taccttgaca agcaatcaga cactcaatat 1141 gtctgcaaaa gaacgttagt ggacagaggc tggggaaatg gatgtggact ttttggcaaa 1201 gggagcctgg tgacatgcgc taagtttgca tgctccaaga aaatgaccgg gaagagcatc 1261 cagccagaga atctggagta ccggataatg ctgtcagttc atggctccca gcacagtggg 1321 atgatcgtta atgacacagg acatgaaact gatgagaata gagcgaaggt tgagataacg 1381 cccaattcac caagagccga agccaccctg gggggttttg gaagcctagg acttgattgt 1441 gaaccgagga caggccttga cttttcagat ttgtattact tgactatgaa taacaagcac 1501 tggttggttc acaaggagtg gttccacgac attccattac cttggcacgc tggggcagac 1561 accggaactc cacactggaa caacaaagaa gcactggtgg agttcaagga cgcacatgcc 1621 aaaaggcaaa ctgtcgtggt tctagggagt caagaaggag cagttcacac ggcccttgct 1681 ggagctctgg aggctgagat ggatggtgca aagggaaggc tgtcctctgg ccacttgaaa 1741 tgtcgcctga aaatggataa acttagattg aagggcgtgt catactcctt gtgtaccgca 1801 gcgttcacat tcaccaagat cccggctgaa acactgcacg ggacagtcac agtggaggta 1861 cagtacgcag ggacagatgg accttgcaag gttccagctc agatggcggt ggacatgcaa 1921 actctgaccc cagttgggag gttgataacc gctaaccccg taatcactga aagcactgag 1981 aactctaaga tgatgctgga acttgatcca ccatttgggg actcttacat tgtcatagga 2041 gtcggggaga agaagatcac ccaccactgg cacaggagtg gcagcaccat tggaaaagca 2101 tttgaagcca ctgtgagagg tgccaagaga atggcagtct tgggagacac agcctgggac 2161 tttggatcag ttggaggcgc tctcaactca ttgggcaagg gcatccatca aatttttgga 2221 gctgctttca aatcattgtt tggaggaatg tcctggttct cacaaattct cattggaacg 2281 ttgctgatgt ggttgggtct gaacacaaag aatggatcta tttcccttat gtgcttggcc 2341 ttagggggag tgttgatctt cttatccaca gccgtctctg ctgatgtggg gtgctcggtg 2401 gacttctcaa agaaggagac gagatgcggt acaggggtgt tcgtctataa cgacgttgaa 2461 gcctggaggg acaggtacaa gtaccatcct gactcccccc gtagattggc agcagcagtc 2521 aagcaagcct gggaagatgg tatctgcggg atctcctctg tttcaagaat ggaaaacatc 2581 atgtggagat cagtagaagg ggagctcaac gcaatcctgg aagagaatgg agttcaactg 2641 acggtcgttg tgggatctgt aaaaaacccc atgtggagag ctccacagag attgcccgtg 2701 cctgtgaacg agctgcccca cggctggaag gcttggggga aatcgtactt cgtcagagca 2761 gcaaagacaa ataacagctt tgtcgtggat ggtgacacac tgaaggaatg cccactcaaa 2821 catagagcat ggaacagctt tcttgtggag gatcatgggt tcggggtatt tcacactagt 2881 gtctggctca aggttagaga agattattca ttagagtgtg atccagccgt tattggaaca 2941 gctgttaagg gaaaggaggc tgtacacagt gatctaggct actggattga gagtgagaag 3001 aatgacacat ggaggctgaa gagggcccat ctgatcgaga tgaaaacatg tgaatggcca 3061 aagtcccaca cattgtggac agatggaata gaagagagtg atctgatcat acccaagtct 3121 ttagctgggc cactcagcca tcacaatacc agagagggct acaggaccca aatgaaaggg 3181 ccatggcaca gtgaagagct tgaaattcgg tttgaggaat gcccaggcac taaggtccac 3241 gtggaggaaa catgtggaac aagaggacca tctctgagat caaccactgc aagcggaagg 3301 gtgatcgagg aatggtgctg cagggagtgc acaatgcccc cactgtcgtt ccgggctaaa 3361 gatggctgtt ggtatggaat ggagataagg cccaggaaag aaccagaaag caacttagta 3421 aggtcaatgg tgactgcagg atcaactgat cacatggatc acttctccct tggagtgctt 3481 gtgattctgc tcatggtgca ggaagggcta aagaagagaa tgaccacaaa gatcatcata 3541 agcacatcaa tggcagtgct ggtagctatg atcctgggag gattttcaat gagtgacctg 3601 gctaagcttg caattttgat gggtgccacc ttcgcggaaa tgaacactgg aggagatgta 3661 gctcatctgg cgctgatagc ggcattcaaa gtcagaccag cgttgctggt atctttcatc 3721 ttcagagcta attggacacc ccgtgaaagc atgctactgg ccttggcctc gtgtcttttg 3781 caaactgcga tctccgcctt ggaaggcgac ctgatggttc tcatcaatgg ttttgctttg 3841 gcctggttgg caatacgagc gatggttgtt ccacgcactg ataacatcac cttggcaatc 3901 ctggctgctc tgacaccact ggcccggggc acactgcttg tggcgtggag agcaggcctt 3961 gctacttgcg gggggtttat gctcctctct ctgaagggaa aaggcagtgt gaagaagaac 4021 ttaccatttg tcatggccct gggactaacc gctgtgaggc tggtcgaccc catcaacgtg 4081 gtgggactgc tgttgctcac aaggagtggg aagcggagct ggccccctag cgaagtactc 4141 acagctgttg gcctgatatg cgcattggct ggagggttcg ccaaggcaga tatagagatg 4201 gctgggccca tggccgcggt cggtctgcta attgtcagtt acgtggtctc aggaaagagt 4261 gtggacatgt acattgaaag agcaggtgac atcacatggg aaaaagatgc ggaagtcact 4321 ggaaacagtc cccggctcga tgtggcgcta gatgagagtg gtgatttctc cctggtggag 4381 gatgacggtc cccccatgag agagatcata ctcaaggtgg tcctgatgac catctgtggc 4441 atgaacccaa tagccatacc ctttgcagct ggagcgtggt acgtatacgt gaagactgga 4501 aaaaggagtg gtgctctatg ggatgtgcct gctcccaagg aagtaaaaaa gggggagacc 4561 acagatggag tgtacagagt aatgactcgt agactgctag gttcaacaca agttggagtg 4621 ggagttatgc aagagggggt ctttcacact atgtggcacg tcacaaaagg atccgcactg 4681 agaagcggtg aagggagact tgatccatac tggggagatg tcaagcagga tctggtgtca 4741 tactgtggtc catggaagct agatgccgcc tgggacgggc acagcgaggt gcagctcttg 4801 gccgtgcccc ccggagagag agcgaggaac atccagactc tgcccggaat atttaagaca 4861 aaggatgggg acattggagc ggttgcgctg gattacccag caggaacttc aggatctcca 4921 atcctagaca agtgtgggag agtgatagga ctttatggca atggggtcgt gatcaaaaat 4981 gggagttatg ttagtgccat cacccaaggg aggagggagg aagagactcc tgttgagtgc 5041 ttcgagcctt cgatgctgaa gaagaagcag ctaactgtct tagacttaca tcctggagct 5101 gggaaaacca ggagagttct tcctgaaata gtccgtgaag ccataaaaac aagactccgt 5161 actgtgatct tagctccaac cagggttgtc gctgctgaaa tggaggaggc ccttagaggg 5221 cttccagtgc gttatatgac aacagcagtc aatgtcaccc actctggaac agaaatcgtc 5281 gacttaatgt gccatgccac cttcacttca cgtctactac agccaatcag agtccccaac 5341 tataatctgt atattatgga tgaggcccac ttcacagatc cctcaagtat agcagcaaga 5401 ggatacattt caacaagggt tgagatgggc gaggcggctg ccatcttcat gaccgccacg 5461 ccaccaggaa cccgtgacgc atttccggac tccaactcac caattatgga caccgaagtg 5521 gaagtcccag agagagcctg gagctcaggc tttgattggg tgacggatca ttctggaaaa 5581 acagtttggt ttgttccaag cgtgaggaac ggcaatgaga tcgcagcttg tctgacaaag 5641 gctggaaaac gggtcataca gctcagcaga aagacttttg agacagagtt ccagaaaaca 5701 aaacatcaag agtgggactt tgtcgtgaca actgacattt cagagatggg cgccaacttt 5761 aaagctgacc gtgtcataga ttccaggaga tgcctaaagc cggtcatact tgatggcgag 5821 agagtcattc tggctggacc catgcctgtc acacatgcca gcgctgccca gaggaggggg 5881 cgcataggca ggaatcccaa caaacctgga gatgagtatc tgtatggagg tgggtgcgca 5941 gagactgacg aagaccatgc acactggctt gaagcaagaa tgctccttga caatatttac 6001 ctccaagatg gcctcatagc ctcgctctat cgacctgagg ccgacaaagt agcagccatt 6061 gagggagagt tcaagcttag gacggagcaa aggaagacct ttgtggaact catgaaaaga 6121 ggagatcttc ctgtttggct ggcctatcag gttgcatctg ccggaataac ctacacagat 6181 agaagatggt gctttgatgg cacgaccaac aacaccatac tggaagacag tgtgccggca 6241 gaggtgtgga ccagacacgg agagaaaaga gtgctcaaac cgaggtggat ggacgccaga 6301 gtttgttcag atcatgcggc cctgaagtca ttcaaggagt ttgccgctgg gaaaagagga 6361 gcggcttttg gagtgatgga agccttggga acactgccag gacacatgac agagagattc 6421 caggaagcca ttgacaacct cgctgtgctc atgcgggcag agactggaag caggccttac 6481 aaagccgcgg cggcccaatt gccggagacc ctagagacca ttatgctttt ggggttgctg 6541 ggaacagtct cgctgggaat ctttttcgtc ttgatgagga acaagggcat agggaagatg 6601 ggctttggaa tggtgaccct tggggccagt gcatggctca tgtggctctc ggaaattgag 6661 ccagccagaa ttgcatgtgt cctcattgtt gtgttcctat tgctggtggt gctcatacct 6721 gagccagaaa agcaaagatc tccccaggac aaccaaatgg caatcatcat catggtagca 6781 gtaggtcttc tgggcttgat taccgccaat gaactcggat ggttggagag aacaaagagt 6841 gacctaagcc atctaatggg aaggagagag gagggagcaa ccataggatt ctcaatggac 6901 attgacctgc ggccagcctc agcttgggcc atctatgctg ccttgacaac tttcattacc 6961 ccagccgtcc aacatgcagt gaccacttca tacaacaact actccttaat ggcgatggcc 7021 acgcaagctg gagtgttgtt tggtatgggc aaagggatgc cattctacgc atgggacttt 7081 ggagtcccgc tgctaatgat aggttgctac tcacaattaa cacccctgac cctaatagtg 7141 gccatcattt tgctcgtggc gcactacatg tacttgatcc cagggctgca ggcagcagct 7201 gcgcgtgctg cccagaagag aacggcagct ggcatcatga agaaccctgt tgtggatgga 7261 atagtggtga ctgacattga cacaatgaca attgaccccc aagtggagaa aaagatggga 7321 caggtgctac tcatagcagt agccgtctcc agcgccatac tgtcgcggac cgcctggggg 7381 tggggggagg ctggggccct gatcacagcc gcaacttcca ctttgtggga aggctctccg 7441 aacaagtact ggaactcctc tacagccact tcactgtgta acatttttag gggaagttac 7501 ttggctggag cttctctaat ctacacagta acaagaaacg ctggcttggt caagagacgt 7561 gggggtggaa caggagagac cctgggagag aaatggaagg cccgcttgaa ccagatgtcg 7621 gccctggagt tctactccta caaaaagtca ggcatcactg aggtgtgcag agaagaggcc 7681 cgccgcgccc tcaaggacgg tgtggcaacg ggaggccatg ctgtgtcccg aggaagtgca 7741 aagctgagat ggttggtgga gcggggatac ctgcagccct atggaaaggt cattgatctt 7801 ggatgtggca gagggggctg gagttactac gccgccacca tccgcaaagt tcaagaagtg 7861 aaaggataca caaaaggagg ccctggtcat gaagaacccg tgttggtgca aagctatggg 7921 tggaacatag tccgtcttaa gagtggggtg gacgtctttc atatggcggc tgagccgtgt 7981 gacacgttgc tgtgtgacat aggcgagtca tcatctagtc ctgaagtgga agaagcacgg 8041 acgctcagag tcctctccat ggtgggggat tggcttgaaa gaagaccagg agccttttgt 8101 ataaaagtgt tgtgcccata caccagcact atgatggaaa ccctggagcg actgcagcgt 8161 aggtatgggg gaggactggt cagagtgcca ctctcccgca actctacaca tgagatgtac 8221 tgggtctctg gagcgaaaag caacaccata aaaagtgtgt ccaccacgag ccagctcctc 8281 ttggggcgca tggacgggcc taggaggcca gtgaaatatg aggaggatgt gaatctcggc 8341 tctggcacgc gggctgtggt aagctgcgct gaagctccca acatgaagat cattggtaac 8401 cgcattgaaa ggatccgcag tgagcacgcg gaaacgtggt tctttgacga gaaccaccca 8461 tataggacat gggcttacca tggaagctat gaggccccca cacaagggtc agcgtcctct 8521 ctaataaacg gggttgtcag gctcctgtca aaaccctggg atgtggtgac tggagtcaca 8581 ggaatagcca tgaccgacac cacaccgtat ggtcagcaaa gagttttcaa ggaaaaagtg 8641 gacactaggg tgccagaccc ccaagaaggc actcgtcagg ttatgagcat ggtctcttcc 8701 tggttgtgga aagagctagg caaacacaaa cggccacgag tctgtaccaa agaagagttc 8761 atcaacaagg ttcgtagcaa tgcagcatta ggggcaatat ttgaagagga aaaagagtgg 8821 aagactgcag tggaagctgt gaacgatcca aggttctggg ctctagtgga caaggaaaga 8881 gagcaccacc tgagaggaga gtgccagagt tgtgtgtaca acatgatggg aaaaagagaa 8941 aagaaacaag gggaatttgg aaaggccaag ggcagccgcg ccatctggta tatgtggcta 9001 ggggctagat ttctagagtt cgaagccctt ggattcttga acgaggatca ctggatgggg 9061 agagagaact caggaggtgg tgttgaaggg ctgggattac aaagactcgg atatgtccta 9121 gaagagatga gttgcatacc aggaggaagg atgtatgcag atgacactgc tggctgggac 9181 acccgcatca gcaggtttga tctggagaat gaagctctaa tcaccaacca aatggagaaa 9241 gggcacaggg ccttggcatt ggccataatc aagtacacat accaaaacaa agtggtaaag 9301 gtccttagac cagctgaaaa agggaaaaca gttatggaca ttatttcaag acaagaccaa 9361 agggggagcg gacaagttgt cacttacgct cttaacacat ttaccaacct agtggtgcaa 9421 ctcattcgga atatggaggc tgaggaagtt ctagagatgc aagacttgtg gctgctgcgg 9481 aggtcagaga aagtgaccaa ctggttgcag agcaacggat gggataggct caaacgaatg 9541 gcagtcagtg gagatgattg cgttgtgaag ccaattgatg ataggtttgc acatgccctc 9601 aggttcttga atgatatggg aaaagttagg aaggacacac aagagtggaa accctcaact 9661 ggatgggaca actgggaaga agttccgttt tgctcccacc acttcaacaa gctccatctc 9721 aaggacggga ggtccattgt ggttccctgc cgccaccaag atgaactgat tggccgggcc 9781 cgcgtctctc caggggcggg atggagcatc cgggagactg cttgcctagc aaaatcatat 9841 gcgcaaatgt ggcagctcct ttatttccac agaagggacc tccgactgat ggccaatgcc 9901 atttgttcat ctgtgccagt tgactgggtt ccaactggga gaactacctg gtcaatccat 9961 ggaaagggag aatggatgac cactgaagac atgcttgtgg tgtggaacag agtgtggatt 10021 gaggagaacg accacatgga agacaagacc ccagttacga aatggacaga cattccctat 10081 ttgggaaaaa gggaagactt gtggtgtgga tctctcatag ggcacagacc gcgcaccacc 10141 tgggctgaga acattaaaaa cacagtcaac atggtgcgca ggatcatagg tgatgaagaa 10201 aagtacatgg actacctatc cacccaagtt cgctacttgg gtgaagaagg gtctacacct 10261 ggagtgctgt aa
niman Posted February 5, 2016 Author Report Posted February 5, 2016 Volume 22, Number 5—May 2016LetterPhylogeny of Zika Virus in Western Hemisphere, 2015Robert S. Lanciotti , Amy J. Lambert, Mark Holodniy, Sonia Saavedra, and Leticia del Carmen Castillo SignorAuthor affiliations: Centers for Disease Control and Prevention, Fort Collins, Colorado, USA (R.S. Lanciotti, A.J. Lambert); Department of Veterans Affairs, Palo Alto, California, USA (M. Holodniy); VA Caribbean Health Care System, San Juan, Puerto Rico, USA (S. Saavedra); Laboratorio Nacional de Salud Guatemala, Villa Nueva, Guatemala (L. del Carmen Castillo Signor)Main ArticleFigureFigure. Phylogenetic tree of Zika virus isolates identified from Guatemala and Puerto Rico in December 2015 (indicated in boldface) compared with reference isolates obtained from GenBank. The isolates from Guatemala and Puerto Rico grouped with other Asian genotype viruses. The tree was derived by neighbor-joining methods (bootstrapped 1,000 times) using complete-genome sequences. Location, year identified, and GenBank strain identification for the viruses used in tree construction are shown. Scale bar indicates number of nucleotide substitutions per site. GenBank accession nos.: KU321639 (Brazil 2015 SPH2015), KJ776791 (French Polynesia H/PF/2013), KF383115 (Central African Republic ARB1362), KF383116 (Senegal 1968 ArD7117), KF383117 (Senegal 1997 ArD128000), KF383118 (Senegal 2001 ArD157995), KF383119 (Senegal 2001 ArD158084), KF268948 (CAR 1979 ARB13565), KF268949 (CAR 1980 ARB15076), KF268950 (CAR 1976 ARB7701), EU545988 (Yap 2007), KF993678 (Thailand 2013 PLCal_ZV), JN860885 (Cambodia 2010 FSS13025), HQ234499 (Malaysia 1966 P6-740), HQ234501 (Senegal 1984 ArD41519), HQ234500 (Nigeria 1968 IbH 30656), LC002520 (Uganda 1947 MR766), KU501215 (Puerto Rico PRVABC59), KU501216 (Guatemala 8375), and KU501217 (Guatemala 103344).
niman Posted February 5, 2016 Author Report Posted February 5, 2016 equences producing significant alignments:Select:AllNone Selected:0AlignmentsDownloadGenBankGraphicsDistance tree of resultsShow/hide columns of the table presenting sequences producing significant alignmentsSequences producing significant alignments:Select for downloading or viewing reportsDescriptionMax scoreTotal scoreQuery coverE valueIdentAccessionSelect seq gb|KJ776791.1|Zika virus strain H/PF/2013 polyprotein gene, complete cds1839318393100%0.099%KJ776791.1Select seq gb|KU365779.1|Zika virus strain BeH819966 polyprotein gene, complete cds1838418384100%0.099%KU365779.1Select seq gb|KU321639.1|Zika virus strain ZikaSPH2015, complete genome1838418384100%0.099%KU321639.1Select seq gb|KU365780.1|Zika virus strain BeH815744 polyprotein gene, complete cds1837218372100%0.099%KU365780.1Select seq gb|KU365777.1|Zika virus strain BeH818995 polyprotein gene, complete cds1836618366100%0.099%KU365777.1Select seq gb|KU365778.1|Zika virus strain BeH819015 polyprotein gene, complete cds1835418354100%0.099%KU365778.1Select seq gb|KU312312.1|Zika virus isolate Z1106033 polyprotein gene, complete cds1835418354100%0.099%KU312312.1Select seq gb|JN860885.1|Zika virus isolate FSS13025 polyprotein gene, partial cds177621776299%0.098%JN860885.1Select seq gb|KF993678.1|Zika virus strain PLCal_ZV from Canada polyprotein gene, partial cds177061770698%0.099%KF993678.1Select seq gb|EU545988.1|Zika virus polyprotein gene, complete cds1759817598100%0.098%EU545988.1Select seq gb|HQ234499.1|Zika virus isolate P6-740 polyprotein gene, partial cds164291642999%0.095%HQ234499.1
niman Posted February 9, 2016 Author Report Posted February 9, 2016 UpdateSequences producing significant alignments:Select:AllNone Selected:0AlignmentsDownloadGenBankGraphicsDistance tree of resultsShow/hide columns of the table presenting sequences producing significant alignmentsSequences producing significant alignments:Select for downloading or viewing reportsDescriptionMax scoreTotal scoreQuery coverE valueIdentAccessionSelect seq gb|KU501217.1|Zika virus strain 8375 polyprotein gene, complete cds1852518525100%0.0100%KU501217.1Select seq gb|KU501216.1|Zika virus strain 103344 polyprotein gene, complete cds1852018520100%0.099%KU501216.1Select seq gb|KU509998.1|Zika virus strain Haiti/1225/2014, complete genome1839918399100%0.099%KU509998.1Select seq gb|KJ776791.1|Zika virus strain H/PF/2013 polyprotein gene, complete cds1839318393100%0.099%KJ776791.1Select seq gb|KU365779.1|Zika virus strain BeH819966 polyprotein gene, complete cds1838418384100%0.099%KU365779.1Select seq gb|KU321639.1|Zika virus strain ZikaSPH2015, complete genome1838418384100%0.099%KU321639.1Select seq gb|KU365780.1|Zika virus strain BeH815744 polyprotein gene, complete cds1837218372100%0.099%KU365780.1Select seq gb|KU365777.1|Zika virus strain BeH818995 polyprotein gene, complete cds1836618366100%0.099%KU365777.1Select seq gb|KU647676.1|Zika virus strain MRS_OPY_Martinique_PaRi_2015 polyprotein gene, complete cds1835718357100%0.099%KU647676.1Select seq gb|KU365778.1|Zika virus strain BeH819015 polyprotein gene, complete cds1835418354100%0.099%KU365778.1Select seq gb|KU312312.1|Zika virus isolate Z1106033 polyprotein gene, complete cds1835418354100%0.099%KU312312.1Select seq gb|KU501215.1|Zika virus strain PRVABC59, complete genome1834518345100%0.099%KU501215.1Select seq gb|JN860885.1|Zika virus isolate FSS13025 polyprotein gene, partial cds177621776299%0.098%JN860885.1Select seq gb|KF993678.1|Zika virus strain PLCal_ZV from Canada polyprotein gene, partial cds177061770698%0.099%KF993678.1Select seq gb|EU545988.1|Zika virus polyprotein gene, complete cds1759817598100%0.098%EU545988.1
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