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Zika First Trimester Infection Linked To Microcephaly Maturín Venezuela


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Published Date: 03/03/2016 15:16:52 Subject: PRO / ESP> Zika - Venezuela: (ANZ) early infection in pregnant, microcephaly, stillborn, confirmation Archive Number:20160303.4067220
 

ZIKA - VENEZUELA: (ANZ) EARLY INFECTION IN PREGNANT, microcephaly, stillborn, 

ProMED-mail statement http://www.promedmail.org ProMED-mail is a program of theInternational Society for Infectious Diseases http://www.isid.org 

Date: February 3, 2016 Source: Rafael Suarez <rafaelsuarezp @ hotmail.com> [. Edited by Jaime Torres] 

a recent case of microcephaly associated confirmed by the zika virius during the first trimester of pregnancy,

in a Venezuelan embarada infection is reported. case report : female patient, 24 years old from Maturin (Edo. Monagas). 

First deed, last menstrual period 14.10.2015. He presented carcacterístico morbilliform rash and malaise on January 5, 2015 (in the 13th week of gestation). Obstetric evaluation that date was normal including sonographic study revealed no alterations in amniotic fluid, placenta and fetus. 

In the ecosonography on February 16, 2016 severe oligoamnios, head diameter was observed in the 3rd percentile (12.8 centimeters ) and hyperechoic Images intraventricular.serological studies performed in week 17 ruled out the occurrence of recent infection with CMV, rubella, dengue and Chicungunya. 

at week 17 + 3 days of gestation at sonogram stillbirth was evident, diagnosed with microcephaly and oligoamnios severe. for research purposes parents authorized the study of various samples of umbilical cord, placenta and brain, which were referred to the Institutes of Tropical Medicine of the Central University of Venezuela, as the Venezuelan Institute for Scientific research (IVIC ). In parallel, they have been sent Confirmatory shows the National Institute of Hygiene "Rafael Rangel" (INHRR), national reference center for diagnosis of infections Zika virus and samples for further study of histopathology and electron microscopy were collected. 

The initial results PCR reaction for Zika practiced in the blood and tissue of the umbilical cord, as in the amniotic fluid, showed the presence of genetic material of the virus in these tissues. Pending the results of PCR in fetal brain parénquma and RT-PCR tests sent to reference laboratory INHRR. Dr. Rafael Suárez.Obstetra, former Professor of the Department of Gynecology and Obstetrics of the Central University of Venezuela Lic. Nahir Martinez, Section of Virology, Institute of Tropical Medicine, Central University of Venezuela Lic. Zoila Moros, Venezuelan Institute for Scientific Research Dr. Jaime R. Torres, Section of Infectious Diseases, Institute of Tropical Medicine, Central University of Venezuela Reported by: Jaime R. Torres <[email protected]- ProMED-ESP ............. .... jt 

[ Thiswould be the first confirmed case of microcephaly associated with recent infection Zika virus, outside the Brazilian context. Previous 2 cases (one patient in the US and one in Slovenia, had a history of infection in Brazil during the first trimester of pregnancy. In a corresponding to a Colombian patient Bucaramanga, recently reviewed by Promed-Eng indigenous case suspect (see below) , no studies or confirmatory PCR virological infection were performed by the Zika virus, either the mother or the product of gestation. Moderator Jaime R. Torres]

Posted
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The first case of a human fetus death from microcephaly (brain damage) caused by Zika virus has been registered in Venezuela, El Nacional reports citing medical experts.

 

MEXICO CITY (Sputnik) – The 24-year-old mother was infected with Zika in January, on the 13th week of her pregnancy, and her unborn baby developed microcephaly as a result and died at 17 weeks, infectologist at the Central University of Venezuela Jaime Torres revealed as cited by the Venezuelan newspaper on Thursday.

 

The Zika virus affects primarily monkeys and humans and is transmitted by daytime-active mosquitoes. Transmission through blood transfusions and sexual intercourse has also been reported.

Zika does not cause serious complications in adults, but it can lead to severe brain defects, such as microcephaly, in newborns.

 

At present, there is no vaccine available to treat the Zika virus. Mosquito control remains crucial to prevent its spread. The diagnosis of Zika virus infections is also very important, especially for the care and monitoring of pregnant women.

 

According to El Nacional, the parents of the dead unborn baby have authorized that samples of umbilical cord, placenta and the fetus’s brain be used for study.

The current Zika outbreak started in Brazil in the spring of 2015. It has since spread across Latin America, with cases having been reported in several European countries and the United States.

Over 300 Zika virus cases and three Zika-related deaths have been confirmed in Venezuela.



Read more: http://sputniknews.com/latam/20160304/1035756583/fetus-death-from-zika-caused-microcephaly-reported.html#ixzz41w4Hjfl4

Posted

Venezuela detected the first case of microcephaly linked with zika

The baby patient no longer had life in week 17 of gestation and presented "a diagnosis of microcephaly," said the doctors

12:21 03/04/2016  REUTERS
 
1402797.jpg

In a test that was made to the umbilical cord tissue doctors they found genetic material from the virus zika.

 
 
 

CARACAS.

Doctors in Venezuela confirmed the first case of microcephaly and fetal death a mother who was infected in the country with the virus zika the beginning of their pregnancy , reported the International Society forInfectious Diseases .

The case adds to the evidence in Brazil on the relationship between zika and microcephaly in infants, which investigates the World Health Organization (WHO), and a report in Colombia of a "probable" case of this anomaly in the fetus of a mother interrupted her pregnancy after suffering the virus.

The baby patient, 24 years old, and had no life in week 17 of gestation and presented "a diagnosis of microcephaly and severe oligoamnios" the medical report signed by four Venezuelan doctors.

The mother showed symptoms of the virus in the first trimester of pregnancy, but at that time or the placenta or the fetus had abnormalities, the study added. the presence of dengue virus, rubella or chikungunya discarded.

In a test that was made to the umbilical cord tissue doctors they found genetic material from the virus zika.

An official of the World Health Organization (WHO) said there is a "growing evidence" about the relationship between the virus and two neurological disorders zika microcephaly and Guillain-Barre syndrome.

In early February, Venezuela reported three deaths and about 5 000 221 patients suspected of having the virus zika, but doctors and non-governmental organizations believe that cases may be many more in a country suffering from an acute shortage of medicines and repellents to avoid the bite of the infected mosquito.

The outbreak was confirmed this year in Panama, Venezuela, El Salvador, Mexico, Suriname, Colombia, Guatemala and Paraguay.

In the circumstances we are living, the situation could be much more dramatic than in other countries in the region, "said Jaime Torres infectious disease specialist at an academic conference that was broadcast on the Internet in February.

Torres, who participated in the study reported the first case of zika relationship with microcephaly in Venezuela, made the warning as 60 percent of the 600,000 pregnant women do not receive adequate prenatal annual control. In most cases, the virus occurs without symptoms that cause alarm.

In Venezuela abortion laws consider as illegal unless threatened the life or health of the woman, but not in the case of the baby.

http://www.excelsior.com.mx/global/2016/03/04/1078837#.VtnVoCF88Ms.twitter

 

Posted

Doctors in Venezuela reported first case of microcephaly in fetus of pregnant infected with Zika

 
March 4, 2016

CARACAS (Reuters) - Doctors in Venezuela confirmed the first case of microcephaly and death of the fetus of a mother who was infected in the country with Zika virus early in her pregnancy, she reported on Friday the International Society for Infectious Diseases.

The case adds to the evidence in Brazil on the relationship between Zika and microcephaly in infants, which investigates the World Health Organization (WHO), and a report in Colombia of a "probable" case of this anomaly in the fetus of a mother interrupted her pregnancy after suffering the virus.

The baby patient, 24 years old, and had no life in week 17 of gestation and presented "a diagnosis of microcephaly and severe oligoamnios" the medical report signed by four Venezuelan doctors.

The mother showed symptoms of the virus in the first trimester of pregnancy, but at that time or the placenta or the fetus had abnormalities, the study added. the presence of dengue virus, rubella or chikungunya discarded.

The Ministry of Health in Venezuela has not yet informed about this case and did not immediately return a request for information made Reuters.

In a test that was made to the umbilical cord tissue doctors found genetic material Zika virus.

An official of the World Health Organization (WHO) said on Friday that there is "growing evidence" about the relationship between Zika virus and two neurological disorders microcephaly and Guillain-Barre syndrome.

In early February, Venezuela reported three deaths and about 5,221 patients suspected of having the virus Zika, but doctors and non-governmental organizations believe that cases may be many more in a country suffering from an acute shortage of medicines and repellents to avoid the bite of the infected mosquito.

The outbreak has been confirmed this year in Panama, Venezuela, El Salvador, Mexico, Suriname, Colombia, Guatemala and Paraguay.

"In the circumstances we are living, the situation could be much more dramatic than in other countries in the region," said Jaime Torres infectious disease specialist at an academic conference that was broadcast on the Internet in February.

Torres, who participated in the study reported the first case Zika's relationship with microcephaly in Venezuela, made the warning as 60 percent of the 600,000 pregnant women do not receive adequate prenatal annual control. In most cases, the virus occurs without symptoms that cause alarm.

In Venezuela abortion laws consider as illegal unless threatened the life or health of the woman, but not in the case of the baby.

(Reporting by Corina Pons, with additional information from Alexandra Ulmer Edited by Javier Leira.)

https://es-us.noticias.yahoo.com/médicos-en-venezuela-reportan-primer-caso-microcefalia-en-170222392.html?soc_src=social-sh&soc_trk=tw

 

Posted
They confirmed the first case of microcephaly and fetal death in Monagas

A report infectólogo the Institute of Tropical Medicine of the Central University of Venezuela, Jaime Torres, revealed the first proven case of microcephaly in Venezuela, in the baby of a patient 24-year-old from Maturin, Monagas state. At week 17 of gestation doctors they found the fetus was dead.

In the description of the case it is reported that the last menstrual period of women occurred in October 2015 and the January 5, 2016 (in the 13th week of pregnancy) presented skin rash and malaise, two characteristic symptoms of zika. "The assessment of that date, including ultrasound examination revealed no alterations in amniotic fluid, placenta and fetus" indicate in the report.

On February 16 and the sonogram revealed a severe reduction in the amount of amniotic fluid and intracerebral calcified structures, both complications that have been associated with the presence of zika. "Practiced Serological studies ruled out the occurrence of recent infection with cytomegalovirus, rubella, dengue or chikungunya".

Three days after studies showed fetal death in utero, diagnosed with microcephaly and decreased amniotic fluid.

The baby's parents authorized that samples of umbilical cord, placenta and brain, which were referred to the IMT and the Venezuelan Institute for Scientific Research (IVIC) was studied.

"In parallel, have been sent Confirmatory shows the National Institute of Hygiene Rafael Rangel, national reference center for diagnosis of infections Zika virus and samples for further study of histopathology and electron microscopy were collected," explained in the document.(The National)

http://www.noticiasdeaqui.net/2016/03/04/confirmaron-primer-caso-de-microcefalia-y-muerte-fetal-en-monagas/

 

Posted
 

CONFIRMS FIRST CASE OF MICROCEPHALY IN VENEZUELA

feto1.520.360

This is the case of a patient 24, whose baby no longer had life in week 17 of gestation, as well as presenting "a diagnosis of microcephaly and severe oligoamnios" says the report.

According to a study signed by four Venezuelan doctors, it was confirmed the first case of microcephaly and fetal death of a mother who was infected with the virus Zika at the beginning of her pregnancy.

This is the case of a patient 24, whose baby no longer had life in week 17 of gestation, as well as presenting "a diagnosis of microcephaly and severe oligoamnios" the report replicated by the International Society for Infectious Diseases and reviewed by Reuters.

further he discloses that the mother had symptoms of Zika virus in the first trimester of pregnancy, but at that time neither the placenta or the fetus had abnormalities. Then the possibility that it was dengue virus, rubella or chikungunya discarded.

The Ministry of Health in Venezuela has not yet informed about this case and has not responded to the request for information that raised the Reuters news agency.

In early February, Venezuela reported three deaths and about 5,221 patients suspected of having the virus Zika. However, doctors and NGOs ensure that cases are more numerous because of the acute shortage of medicines and mosquito repellents virus carrier afflicting the country.

"In the circumstances we are living, the situation could be much more dramatic than in other countries in the region," said Jaime Torres infectious disease specialist at an academic conference that was broadcast on the Internet in February.

Torres, who participated in the study reported the first case Zika's relationship with microcephaly in Venezuela, warned the situation as 60 percent of the 600,000 pregnant women do not receive adequate prenatal annual control. And it should be mentioned that in most cases the virus occurs without symptoms that cause alarm.

The World Health Organization (WHO) continues to investigate the evidence in Brazil on the relationship between Zika and microcephaly in infants. An official of the international organization reiterated Friday that there is "growing evidence" about the relationship between Zika virus and two neurological disorders. Microcephaly and Guillain-Barre syndrome (ES)

http://www.guayanadigital.com.ve/2016/03/04/confirman-primer-caso-de-microcefalia-en-venezuela/

 

Posted

REGRETTABLE! CONFIRMS FIRST CASE OF MICROCEPHALY BY ZIKA IN VENEZUELA: THE BABY DID NOT SURVIVE

  • Friday, March 4, 2016 15:38
  •  

zikaka-cc.jpg

The infectious disease, Jaime Torres, the Institute of Tropical Medicine (IMT) of the Central University of Venezuela (UCV), issued a report that revealed the first proven case of microcephaly in Venezuela.

 

The victim was a baby at 17 weeks gestation in a patient 24 years old, from Maturin, Monagas state. Doctors found that the fetus was lifeless.

 

In the 13th week of pregnancy (January 5, 2016), she presented skin rash and malaise, two characteristic symptoms of Zika, however, "... the assessment that date, including ultrasound examination revealed no alterations in amniotic fluid placenta and fetus ... "Torres said in the report.

 

February 16 for the sonogram and reflected a severe reduction in the amount of amniotic fluid and intracerebral calcified structures, both complications associated with Zika virus. "... Practiced Serological studies ruled out the occurrence of recent infection with cytomegalovirus, rubella, dengue or chikungunya ..." reads the document.

 

19 of the same month the studies found fetal death in utero, diagnosed with microcephaly and decreased amniotic fluid.

 

Thanks to the authorization granted by the baby's parents, samples from the umbilical cord, placenta and brain, were referred to the IMT and the Venezuelan Institute for Scientific Research (IVIC).

 

"... In parallel, have been sent Confirmatory shows the National Institute of Hygiene Rafael Rangel, national reference center for diagnosis of infections Zika virus and samples for further study of histopathology and electron microscopy ... were collected," he explained the infectious disease.

 

Initial results obtained from the test polymerase chain reaction in real-time PCR, performed blood, umbilical cord and amniotic fluid showed the presence in those tissues Zika virus's genetic material.

 

The report also included the rubrics of the obstetrician Rafael Suarez, Nahir Martinez, belonging to the virology section of the IMT and the IVIC Dr. Zoila Moros.

 

http://laiguana.tv/articulos/23078-confirmado-microcefalia-zika-venezuela-imt-ivic

 

 

Posted

Recorded case of microcephaly in fetus by Zika virus in Venezuela

 

Doctors said the 24-year old patient was carrying a baby in week 17 of gestation and had no life because in the first months of gestation contracted the virus and transmitted it to the neonate

Photo: AFP

 

Photo: AFP

Friday March 4 Venezuela doctors confirmed the first case of microcephaly and death of a fetus whose mother was infected by the virus Zika, in the early months of pregnancy, said Friday the International Society for Infectious Diseases.

The 24 year old patient was carrying a baby in week 17 of gestation and had no life, presenting a diagnosis of "severe microcephaly and oligoamnios" the medical report signed by four doctors.

The mother showed symptoms of the virus in the first trimester of pregnancy, however at that time, neither the fetus or the placenta had some type of alterations, Reuters reported on its website.

This case entitled Health, Luisana Melo, still not pronounced, like not respond to a request for information to conduct news agency.

It was learned that the umbilical cord had contained genetic material Zika virus, thanks to a test that was performed to tissue.

It is recalled that in the first days of February were reported in the nation three deaths and at least 5,221 cases of patients suspected of having the virus Zika, although medical and non-governmental organizations believe that there could be many more, before the crisis of shortage It presents the country.

http://www.eltubazodigital.com/noticias-de-venezuela/vida-y-salud/registran-caso-de-microcefalia-en-feto-por-virus-zika-en-venezuela/

 

Posted

Linked to Zika with deformed baby in Venezuela

The International Society for Infectious Diseases reported that doctors in Venezuela confirmed the first case of microcephaly of a baby whose mother was infected with the virus Zika.
  
 100.jpg

March 4, 2016 by Alan Lopez Section InternationalLinked to Zika with deformed baby in Venezuela

The International Society for Infectious Diseases reported that doctors in Venezuelaconfirmed the first case of microcephaly and death of the fetus of a mother who was infected in that country with the virus Zika at the beginning of the process of pregnancy.

Thus, the medical report signed by four Venezuelan doctors reported that the baby patient and had no life at 17 weeks of gestation, and it had a diagnosis ofmicrocephaly and severe oligohydramnios.

The report also noted that the mother, 24 -year-old showed symptoms of the virus Zikain the first trimester of pregnancy, but at that time no alterations or the fetus or placenta were recorded, and that was ruled presence of dengue, rubella or chikungunya virus.

It is noteworthy that in a test conducted to the tissue of the umbilical cord of the baby in Venezuela  doctors found genetic material of the virus, in addition to this case , the evidence adds in Brazil on the relationship between the disease and microcephaly in fetuses and newborns , which is being investigated by the World Health Organization (WHO).

In addition, in early February in Venezuela three deaths and five thousand 221 patients suspected of suffering were recorded virus Zika , although doctors and organizations reported that the number of cases may be much higher because this is a country that suffers from a severe shortage of medicines and repellents to prevent mosquito bites Aedes aegypti , spread of disease.

http://www.sexenio.com.mx/articulo.php?id=72937

 

Posted

Venezuelan doctors confirmed case of microcephaly and death of fetus

This is the case of a patient 24, whose baby no longer had life in week 17 of gestation, as well as presenting "a diagnosis of microcephaly and severe oligoamnios" says the report.

imageRotate
The fetus had no life in week 17 of gestation (FILE)
THE UNIVERSAL
Friday March 4, 2016   6:47 PM
Caracas.- According to a study signed by four Venezuelan doctors, was confirmed the first case of microcephaly and death of the fetus of a mother who was infected with the virus Zika at the beginning of their pregnancy. This is the case of a patient, 24 years, whose baby no longer had life in week 17 of gestation, as well as presenting "a diagnosis of microcephaly and severe oligoamnios" the report replicated by the International Society for Infectious Diseases and reviewed by Reuters. it describes the mother presented Zika virus symptoms in the first trimester of pregnancy, but at that time neither the placenta or the fetus had abnormalities. Then the possibility that it was dengue virus, rubella or chikungunya was discarded. The Ministry of Health in Venezuela has not yet informed about this case and has not responded to the request for information that raised the Reuters news agency. Earlier February, Venezuela reported three deaths and about 5,221 patients suspected of having the virus Zika. However, doctors and NGOs ensure that cases are more numerous because of the acute shortage of medicines and repellent mosquito carrying the virus afflicting the country. "In the circumstances we are living, the situation could be much more dramatic in other countries in the region ,"said infectious disease specialist Jaime Torres at an academic conference that was broadcast on the Internet in February. Torres, who participated in the study's first case reporting relationship of Zika with microcephaly in Venezuela, warned the situation because 60 percent of the 600,000 pregnant women do not receive adequate prenatal annual control. And we should mention that in most cases, the virus without symptoms that cause alarm. The World Health Organization (WHO) continues to investigate the evidence in Brazil on the relationship between Zika and microcephaly in infants. An official of the international organization reiterated Friday that there is "growing evidence" about the relationship between Zika virus and two neurological disorders microcephaly and Guillain-Barre syndrome.
 
 
Posted

Microcephaly confirmed case of death of the fetus by Zika in Venezuela
Mar 5, 2016

The Health Ministry has not reported on this case in Venezuela
The Cooperante.- The International Society for Infectious Diseases, doctors reported that Venezuela confirmed the first case of microcephaly and death of the fetus of a mother who was infected in the country with Zika virus during pregnancy.

As reported by Reuters, the baby of the patient 24, had no life at 17 weeks of gestation and the doctors was diagnosed microcephaly and oligoamnios, ie the unborn had a small amount of amniotic fluid surrounding it and protects.

The mother presented the symptoms of Zika in the first trimester of pregnancy, although no changes were developed or the placenta or the fetus, the disease was detected in the umbilical cord.

The Health Ministry has not reported on this case in Venezuela, although in early February, the country reported three deaths and 5,221 patients suspected of having the Zika virus, without doctors and NGOs have reflected however that may be many most cases.

http://elcooperante.com/alo-luisana-medicos-confirman-primer-caso-de-microcefalia-y-muerte-de-un-feto-por-zika-en-venezuela/

 

Posted

First case of microcephaly and stillbirths in Venezuela

In a test that was made to the umbilical cord tissue doctors found genetic material Zika virus.

 
Posted by: Drafting Sumarium on  [email protected] @sumariumcom
 

(Caracas, Reuters) - Doctors in Venezuela confirmed the first case of microcephaly and death of the fetus of a mother who was infected in the country with the virus Zika at the beginning of her pregnancy, she reported on Friday the International Society for Infectious Diseases.

The case adds to the evidence in Brazil on the relationship between Zika and microcephaly in infants , which investigates the World Health Organization (WHO), and a report in Colombia of a "probable" case of this anomaly in the fetus of a mother interrupted her pregnancy after suffering the virus.

The baby patient, 24 years old, and had no life in week 17 of gestation and presented "a diagnosis of microcephaly and severe oligoamnios" , said the medical report signed by four Venezuelan doctors.

The mother showed symptoms of the virus in the first trimester of pregnancy, but at that time or the placenta or the fetus had abnormalities, the study added. The presence of dengue virus, rubella or chikungunya was discarded .

The Ministry of Health in Venezuela has not yet informed about this case and did not immediately return a request for information made Reuters.

In a test that was made to the umbilical cord tissue doctors found genetic material Zika virus .

An official of the World Health Organization (WHO) said on Friday that there is "growing evidence" about the relationship between Zika virus and two neurological disorders microcephaly and Guillain-Barre syndrome.

In early February, Venezuela reported three deaths and about 5,221 patients suspected of having the virus Zika , but doctors and non - governmental organizations believe that cases may be many more in a country suffering from an acute shortage of medicines and repellents to avoid the bite of the infected mosquito.

The outbreak has been confirmed this year in Panama, Venezuela, El Salvador, Mexico, Suriname, Colombia, Guatemala and Paraguay.

"In the circumstances we are living, the situation could be much more dramatic than in other countries in the region , " said Jaime Torres infectious disease specialist at an academic conference that was broadcast on the Internet in February.

Torres, who participated in the study reported the first case Zika's relationship with microcephaly in Venezuela, made the warning as 60 percent of the 600,000 pregnant women do not receive adequate prenatal annual control. In most cases, the virus occurs without symptoms that cause alarm.

In Venezuela abortion laws consider as illegal unless threatened the life or health of the woman, but not in the case of the baby.

 
 
Category: Venezuela | Keys: Zika
 

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