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The Illinois Department of Public Health is currently reporting 72 cases of Zika virus disease statewide. \ http://www.dph.illinois.gov/topics-services/diseases-and-conditions/zikavirus

The Illinois Department of Public Health is currently reporting 72 cases of Zika virus disease statewide.

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The data will be updated on Thursdays. The next update will be made on Thursday, September 29, 2016. Zika virus detected in Canada, as of September 22, 2016 Country Acquired through sexual transmission Maternal-to-fetal transmission Travel-related Canada 2 2 282 http://www.healthycanadians.gc.ca/diseases-conditions-maladies-affections/disease-maladie/zika-virus/surveillance-eng.php?id=zikacases#s1

The data will be updated on Thursdays. The next update will be made on Thursday, September 29, 2016. Zika virus detected in Canada, as of September 22, 2016 Country Acquired through sexual transmission Maternal-to-fetal transmission Travel-related Canada 2 2 282

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Zika Virus – September 27, 2016. Texas has had 204 reported cases of Zika virus disease. All the cases were associated with travel to an area where Zika is being spread. This count includes 12 pregnant women, two infants infected before birth, and two people who had sexual contact with travelers. Texas Zika Cases by County: County Cases Angelina 1 Bell 6 Bexar 15 Brazos 3 Burnet 1 Cameron 2 Collin 5 Dallas 35 Denton 6 El Paso 3 Ellis 1 Fort Bend 7 Frio 1 Galveston 7 Gray 1 Grayson 1 Gregg 1 Hamilton 1 Harris 56 Jefferson 2 Lee 1 Lubbock 1 Matagorda 1 Medina 1 Midland 1 Montgomery 1 Palo Pinto 1 Randall 1 Tarrant 22 Travis 8 Upshur 1 Val Verde 1 Walker 1 Williamson 5 Webb 2 Wise 1 Total 204

week conf discard untested total weekly increase 37 41 196 246 483 32 36 40 195 216 451 12 35 40 190 209 439 13 34 38 168 220 426 25 33 34 158 209 401 16 32 29 102 254 385 18 31 24 101 242 367 23 30 22 97 225 344 24 29 21 92 207 320 23 28 21 80 196 297 41 27 21 75 160 256 62 26 18 64 112 194 13 25 13 56 112 181 17 24 11 51 102 164 27 23 6 50 81 137 19 22 6 43 69 118 23 21 6 41 48 95 7 20 5 26 57 88 7 19 5 26 50 81 9 18 5 24 43 72 14 17 5 21 32 58 8 16 4 20 26 50 6 15 4 18 22 44 11

intensified surveillance of microcephaly Review 23 September 2016 Among the epidemiological weeks 01 to 37 of 2016 have been confirmed forty-one (41) cases associated with microcephaly Zika virus, 196 cases were dismissed and 246 cases are in study. http://www.ins.gov.co/boletin-epidemiologico/Boletn Epidemiolgico/2016 Boletin epidemiologico semana 37.pdf

Four suspected Zika microcephaly cases in Thailand Filed Under: Zika Stephanie Soucheray | News Reporter | CIDRAP News | Sep 26, 2016 Share Tweet LinkedIn Email Print & PDF aedes_aegypti-sanofi_pasteur.jpg CDC, James Gathany Yesterday Thailand said authorities are investigating four microcephaly cases, while the Philippines and Singapore today reported more cases of Zika virus. Florida, meanwhile, is seeing more locally acquired cases, as well. Zika-linked microcephaly in 3 infants, 1 fetus The Bangkok Post reported that Thailand's Department of Disease Control is investigating three babies born with smaller-than-average heads. Another woman, who is 36 weeks pregnant, has a fetus with an abnormally small head detected on ultrasound. She is 1 of 33 pregnant women in the country's "Zika watch areas" under surveillance for any birth defects linked to the mosquito-borne disease. Amnuay Gajeena, MD, director-general of Thailand's Department of Disease Control, said Zika is not endemic in the country, and that three to four cases of microcephaly are consistent with the 1% to 30% incidence of Zika-related microcephaly seen in other countries. Elsewhere, the Philippines now has 12 confirmed cases of Zika virus, after 3 new cases were identified by the Department of Health (DOH) over the weekend. Eight of the 12 are ininvolve women, and 1 of the cases involves a 22-year-old from Cebu who is 19 weeks pregnant. And Singapore's National Environment Agency (NEA) announced today there were 393 cases of Zika in the city-state. The pace of transmission is slowing down after hundreds of cases were reported at the beginning of the month; only 13 cases have been detected since Sep 18. More locally transmitted cases in Florida On the other side of the world, Florida Health, Florida's health department, announced 10 more cases of locally transmitted Zika virus today. Three of the cases date back to July, when active transmission was occurring in the Wynwood neighborhood of Miami and do not represent new areas of transmission. The other seven cases are in Palm Beach (1), Miami Beach (1), and Miami-Dade County (5). Florida Health said officials are still investigating where the disease was transmitted in Miami-Dade County, and the department is continuing door-to-door outreach in that county, as well as in Pinellas and Palm Beach counties. There are now 105 non-travel–related Zika cases in Florida and 689 travel-related cases. Pregnant women in the state and travelers are still advised to avoid unnecessary travel to the Miami Beach area, where Zika virus is still being actively transmitted. Sanofi gets $43 million for vaccine development Finally today, Reuters reports that the US Department of Health and Human Services (HHS) has awarded $43 million in Zika vaccine development funds to Sanofi Pasteur, the French drug maker that also manufactures the yellow fever and dengue vaccine. The money is meant to speed the vaccine development process, which could see mid-level trials as soon as 2018. According to Reuters, the contract runs through June 2022, but if the data are positive, it can be extended for up to an additional $130.45 million for late-stage trials. The money comes from HHS's Biomedical Advanced Research and Development Authority (BARDA). See also: Sep 25 Bangkok Post story Sep 26 Philippines DOH update Sep 26 Singapore NEA update Sep 26 Florida Health update Sep 26 Reuters story http://www.cidrap.umn.edu/news-perspective/2016/09/four-suspected-zika-microcephaly-cases-thailand

Four babies suspected to have Zika 25 Sep 2016 at 04:00 874 viewed0 comments NEWSPAPER SECTION: NEWS | WRITER: POST REPORTERS Health authorities are investigating whether three babies born with smaller... Please credit and share this article with others using this link: http://www.bangkokpost.com/news/general/1094193/

ASIA PACIFIC Thailand investigates four cases of suspected Zika-linked microcephaly Posted 27 Sep 2016 16:38 Updated 27 Sep 2016 16:45 Microcephaly is a rare neurological disorder that causes a baby's head to be smaller than normal and prevents its brain from fully developing. (Photo: AFP/Christophe Simon) ENLARGE CAPTION ? Email More A A BANGKOK: Thailand is investigating four suspected cases of Zika-related microcephaly in three babies and a 36-week old unborn baby, the public health minister said on Tuesday (Sep 27), in what could be the first cases of Zika-linked microcephaly in Southeast Asia. Several countries in Southeast Asia have reported increasing cases of infection from the mosquito-borne Zika virus but Thailand has one of the highest numbers in the region, with 349 confirmed since January, including 25 pregnant women. Public Health Minister Piyasakon Sakolsatayadorn said authorities needed to be thorough in their investigation of the cases as confirmation would be "sensitive". "The lab results will take at least two days because we have to be thorough with this as it is a big deal and a link hasn't been detected before," Piyasakon told Reuters. "This is a sensitive matter for Thailand," he said. U.S. health officials have concluded that Zika infections in pregnant women can cause microcephaly, a birth defect marked by small head size that can lead to severe developmental problems in babies. Piyasakon said the three babies were born with small heads and an ultrasound appeared to indicate the unborn baby had a small head. Of the four mothers, two were diagnosed with Zika when they were pregnant but two were not confirmed to have had Zika, said Apichai Mongkol, director-general of the ministry's Department of Medical Sciences. If a Thai case were confirmed, it would be the first in Southeast Asia, the World Health Organization (WHO) said in a statement emailed to Reuters. The connection between Zika and microcephaly first came to light last year in Brazil, which has confirmed more than 1,600 cases of microcephaly that it considers to be related to Zika infections in the mothers. MONITORING Some health experts have accused Thailand, which has a thriving tourist industry, of playing down the risk from Zika. But officials dismiss that saying the response has been adequate and another mosquito-born disease, dengue, which can be deadly, is a bigger threat. The director-general of Thailand's Disease Control Department, Amnuay Gajeena, said the four cases were being monitored but he declined to say exactly where they were suspected of contracting the virus. "It is not in Bangkok," Amnuay told Reuters. "Both the mothers and babies are being tested and we have sent the tests to several labs." There are no specific tests to determine if a baby will be born with microcephaly, but ultrasound scans in the third trimester of pregnancy can identify the problem, according to the WHO. The World Health Organization lists Singapore, the Philippines, Malaysia, Thailand and Vietnam as countries reporting new cases of Zika. Singapore has recorded 393 cases since diagnosing its first in August. It has confirmed 16 pregnant women with the virus. The WHO has also said there is strong scientific consensus that Zika can also cause Guillain-Barre, a rare neurological syndrome that causes temporary paralysis in adults. According to the WHO, there are two major lineages of Zika - an African lineage, which has only been reported in Africa, where the virus was first discovered in 1947, and an Asian lineage of strains. There is no vaccine or treatment for Zika, which is a close cousin of dengue and chikungunya and causes mild fever, rash and red eyes. An estimated 80 percent of people infected have no symptoms, making it difficult for pregnant women to know whether they have been infected. (Additional reporting by Cod Satrusayang and Panarat Thepgumpanat in BANGKOK, Marius Zaharia in SINGAPORE; Writing by Amy Sawitta Lefevre; Editing by Robert Birsel) - Reuters

BANGKOK: Thailand is investigating four suspected cases of Zika-related microcephaly in three babies and a 36-week old unborn baby, the public health minister said on Tuesday (Sep 27), in what could be the first cases of Zika-linked microcephaly in Southeast Asia. http://www.channelnewsasia.com/news/asiapacific/thailand-investigates-four-cases-of-suspected-zika-linked/3159820.html

ACTIVE INVESTIGATIONS Information on Active Investigations When a local case of Zika virus is confirmed through laboratory testing, the department conducts a thorough investigation around the case to determine if additional people are infected. The department interviews and tests close contacts and community members around the case. Knowing if additional people are infected helps the department determine if there is a zone where mosquitoes are transmitting the virus. Not every case results in a designation of active transmission in an area. In some instances, a case of Zika is an isolated incident with no additional people infected. For more information on the department’s testing and investigation process, click here. Current Number of Active Investigations: 11 Miami-Dade County: 7 open investigations Pinellas County: 1 open investigation Palm Beach: 3 open investigations Current Number of Closed Investigations: 18 Miami-Dade County: 15 closed investigations Palm Beach County: 2 closed investigation Broward County: 1 closed investigation Sampling Activities For Active Investigations Miami Beach in Miami-Dade County Total # of Samples Collected Positive Negative Pending Results 1,039 45 990 4 Palm Beach County – 3 Investigations Total # of Samples Collected Positive Negative Pending Results 77 1 76 0 Miami-Dade Investigations Outside of Wynwood and Miami Beach – 7 Investigations Total # of Samples Collected Positive Negative Pending Results 7 5 1 1 Pinellas County – 1 Investigation Total # of Samples Collected Positive Negative Pending Results 71 0 70 1 Wynwood Area in Miami-Dade County – Note: This investigation is closed, but the department is providing the sampling results below for reference. Total # of Samples Collected Positive Negative Pending Results 524 33 491 0 Data as of Sep. 26, 2016 - 3:35pm ET http://www.floridahealth.gov/diseases-and-conditions/zika-virus/index.html?utm_source=flhealthIndex

Pennsylvania Blood Tests Submitted for Zika TestingInformation updated Mondays at 2 p.m. Confirmed Infections: 141* *DOH adopted a new definition for Zika virus infections on 9/26/2016. The case counts have increased because the Centers for Disease Control and Prevention’s new definition includes probable Zika infections. The new infection definition has been applied to all previous Zika tests in Pennsylvania. For greater detail on this new definition, click here. Last update: 09/26/2016 http://www.health.pa.gov/My Health/Diseases and Conditions/U-Z/Zikavirus/Pages/ZikaVirusHomePage.aspx#.V-mIlfArJad

Allegheny County Residents Approved for Zika Testing: 192 CDC Confirmed Cases: 10 Unspecified Flavivirus Infections: 1* (as of September 26, 2016) *- specific virus (dengue/zika) cannot be identified

Pennsylvania Blood Tests Submitted for Zika TestingInformation updated Mondays at 2 p.m. Confirmed Infections: 141* *DOH adopted a new definition for Zika virus infections on 9/26/2016. The case counts have increased because the Centers for Disease Control and Prevention’s new definition includes probable Zika infections. The new infection definition has been applied to all previous Zika tests in Pennsylvania. For greater detail on this new definition, click here. Last update: 09/26/2016

CDPH Weekly Update on Number of Zika Virus Infections in California September 23, 2016 The following table provides the number of travel-associated infections with Zika virus in California residents in 2015 and 2016. CDPH is following CDC testing guidelines. This table is updated every Friday. As of September 23, 2016, there have been 302 travel-associated Zika virus infections in California. • Total infections: 302 • New infections reported this week: 20 • Cumulative number of infections due to sexual transmission: 2 • Cumulative number of infections in pregnant women: 36a o Liveborn infants with birth defects: 2b o Pregnancy losses with birth defects: 0c Zika virus infections in California, 2015-2016d (as of September 23, 2016) County Travel-associated e Locally acquired f Alameda (City of Berkeley) 19g (2) 0 Contra Costa 14 0 Fresno 1 0 Humboldt 2 0 Kern 3 0 Lake 1 0 Los Angeles (City of Long Beach) 76h (5) 0 Marin 4 0 Merced 3 0 Monterey 3 0 Napa 2 0 Orange 22 0 Riverside 7 0 Sacramento 5 0 San Bernardino 12 0 San Diego 45i 0 San Francisco 23 0 San Joaquin 6 0 San Mateo 7 0 Santa Barbara 4 0 Santa Clara 20 0 Santa Cruz 2 0 Solano 1 0 Sonoma 6 0 Stanislaus 2 0 Tulare 3 0 Ventura 3 0 Yolo 4 0 Yuba 2 0 Total 302 0 a Local Health Departments and CDPH are monitoring all pregnant women and their infants b Includes microcephaly, calcium deposits in the brain indicating possible brain damage, excess fluid in the brain cavities and surrounding the brain, absent or poorly formed brain structures, abnormal eye development, or other problems resulting from damage to the brain that affects nerves, muscles and bones, such as clubfoot or inflexible joints. c Includes miscarriage, stillbirths, and terminations with evidence of the birth defects mentioned above d Total number includes laboratory-confirmed and probable infections as defined by the CSTE Position Statement e Persons exposed through travel to an affected area or contact with a traveler f Presumed local mosquito-borne transmission g Includes two residents of the City of Berkeley h Includes five resident of the City of Long Beach I Includes one non-resident https://www.cdph.ca.gov/HealthInfo/discond/Documents/TravelAssociatedCasesofZikaVirusinCA.pdf https://www.cdph.ca.gov/HealthInfo/discond/Documents/TravelAssociatedCasesofZikaVirusinCA.pdf

September 26, 2016 Department of Health Daily Zika Update Contact: Communications [email protected] (850) 245-4111 Tallahassee, Fla.—In an effort to keep Florida residents and visitors safe and aware about the status of the Zika virus, the department will issue a Zika virus update each week day. Updates will include a Zika case count by county and information to keep Floridians informed and prepared. In order to keep the public informed, the department has posted our investigation process here. There are six new travel related cases today with two in Broward, two in Miami-Dade, one in Collier and one in Polk. Please visit our website to see the full list of travel-related cases. There are 10 new non-travel related cases today. One is a Palm Beach resident and the department is investigating where exposure occurred. One is associated with the Miami Beach investigation. Five are Miami-Dade residents and the department is investigating where exposure occurred. Three are cases from July associated with Wynwood that the department just received additional confirmatory test results from CDC. It is important to note that these are not new cases and they do not affect the lift of the Wynwood zone as all had symptom onset in July. DOH continues door-to-door outreach and targeted testing in Pinellas, Palm Beach and Miami-Dade counties and mosquito abatement and reduction activities are also taking place around the locations that are being investigated. DOH believes ongoing transmission is only taking place within the identified area in Miami Beach in Miami-Dade County, see map below. One case does not mean ongoing active transmission is taking place. DOH conducts a thorough investigation by sampling close contacts and community members around each case to determine if additional people are infected. If DOH finds evidence that active transmission is occurring in an area, the media and the public will be notified. For a complete breakdown of non-travel and travel-related Zika infections to-date, please see below. Infection Type Infection Count Travel-Related Infections of Zika 689 Non-Travel Related Infections of Zika 105 Infections Involving Pregnant Women 90 Out of State Cases (not Florida Residents) 10 Total 894 The department is currently conducting 11 active investigations. The department has closed 18 investigations. Information regarding the investigations can be found here. If investigations reveal additional areas of active transmission, the department will announce a defined area of concern. The department has conducted Zika virus testing for more than 8,297 people statewide. Florida currently has the capacity to test 6,573 people for active Zika virus and 8,516 for Zika antibodies. At Governor Scott’s direction, all county health departments now offer free Zika risk assessment and testing to pregnant women. Florida’s small case cluster is not considered widespread transmission, however, pregnant women are advised to avoid non-essential travel to the impacted area in Miami-Dade County (see map below). If you are pregnant and must travel or if you live or work in the impacted area, protect yourself from mosquito bites by wearing insect repellent, long clothing and limiting your time outdoors. According to CDC guidance, providers should consider testing all pregnant women with a history of travel to a Zika affected area for the virus. It is also recommended that all pregnant women who reside in or travel frequently to the area where active transmission is likely occurring be tested for Zika in the first and second trimester. Pregnant women in the identified area can contact their medical provider or their local county health department to be tested and receive a Zika prevention kit. CDC recommends that a pregnant woman with a history of Zika virus and her provider should consider additional ultrasounds. Additionally, the department is working closely with the Healthy Start Coalition of Miami-Dade County to identify pregnant women in the impacted areas to ensure they have access to resources and information to protect themselves. CDC recommends that a pregnant woman with a history of Zika virus and her provider should consider additional ultrasounds. Pregnant women can contact their local county health department for Zika risk assessment and testing hours and information. A Zika risk assessment will be conducted by county health department staff and blood and/or urine samples may be collected and sent to labs for testing. It may take one to two weeks to receive results. Florida has been monitoring pregnant women with evidence of Zika regardless of symptoms. The total number of pregnant women who have been or are being monitored is 90. On Feb. 12, Governor Scott directed the State Surgeon General to activate a Zika Virus Information Hotline for current Florida residents and visitors, as well as anyone planning on traveling to Florida in the near future. The hotline, managed by the Department of Health, has assisted 6,578 callers since it launched. The number for the Zika Virus Information Hotline is 1-855-622-6735. The department urges Floridians to drain standing water weekly, no matter how seemingly small. A couple drops of water in a bottle cap can be a breeding location for mosquitoes. Residents and visitors also need to use repellents when enjoying the Florida outdoors. For more information on DOH action and federal guidance, please click here. For resources and information on Zika virus, click here. Miami Beach Map About the Florida Department of Health The department, nationally accredited by the Public Health Accreditation Board, works to protect, promote, and improve the health of all people in Florida through integrated state, county and community efforts. Follow us on Twitter at @HealthyFla and on Facebook. For more information about the Florida Department of Health, please visit www.FloridaHealth.gov.