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Confirmed Microcephaly Cases In Brazil Increase To 1326


niman

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Babies with microcephaly cases reach 1,326 in 24 states and the Federal District

UOL's in Sao Paulo

 
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  • Nacho Doce / Reuters

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Brazil had 1,326 cases of microcephaly or nervous system damage reported between October 2015 and May 7, according to the Ministry of Health report released on Wednesday (11). Until last week, 1,271 cases were recorded. The surge of children born with neurological problems are associated with zika epidemic virus transmitted by the mosquito Aedes aegypti.

The cases of microcephaly registered in the country occurred in 484 municipalities in 24 states and the Federal District. Only Acre and Santa Catarina have no records.Most cases (1.190), however, is still concentrated in the Northeast.

According to the pulp were 56 deaths recorded after childbirth or during pregnancy whose relationship with microcephaly was confirmed. There are 174 deaths under investigation. In addition, there are still 7,438 pregnant women with suspected cases and 3,433 still under investigation.

Cases discarded, it was not confirmed microcephaly or where the malformation is not associated with zika, totaling 2,679 since the beginning of the investigation.Microcephaly can be caused by other diseases such as syphilis, toxoplasmosis, rubella and herpes viral. 

According to the ministry, 205 cases were confirmed by specific laboratory criteria for zika virus. However, the folder considers that there was infection zika most of the babies with mothers who had a final diagnosis of microcephaly.

 

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Virus causes brain cells to self-destruct

The infection zika virus triggers the cells of the human brain in forming an immune response that leads to self-destruction . The discovery was made by scientists at the University of California (UC) in San Diego (USA) and published last week in the journal Cell.

According to the authors of the article, the death of brain stem cells after infection is associated with microcephaly cases caused by viruses. Block the innate immune response of the brain stem cells may be an alternative for them to survive the infection, reducing the possibility of occurrence of the malformation.

Previous studies with minicérebros infected zika helped establish the connection between viral infection and death of neural stem cells. The group led by Brazilian Stevens Rehen, the Federal University of Rio de Janeiro and the D'Or Institute for Research and Education (er), used the Organoids in a study published in April in the journal Science, to conclude that the zika virus actually has the ability to infect and kill human brain cells.

Also in April, an American University Johns Hopkins group used the technique to prove that zika virus prefers neural stem cells. Now, the latest study added another piece to the puzzle: the role of the immune system.

http://noticias.uol.com.br/saude/ultimas-noticias/redacao/2016/05/11/bebes-com-microcefalia-chegam-a-1326-casos-em-24-estados-e-no-df.htm

 

Edited by niman
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