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On 14 September 2015, the National IHR Focal Point for Portugal notified WHO of a confirmed human case of West Nile virus (WNV) infection. The patient is a 71-year-old male from the town of Almancil (Loulé municipality) – Algarve Region, Portugal with no recent history of travel. On 20 July, he was hospitalized with neurological symptoms. Following a full recovery, on 4 August, the patient was discharged from hospital.

Seroconversion (IgM and IgG) was confirmed in two separate samples on 7 and 19 August. Real-time PCR was negative in the first sample. Neutralization tests were positive for WNV on samples collected on 14 September.

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