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In October 2015, the Ministry of Health (MoH) of Brazil notified PAHO/WHO of an unusual increase in the number of cases of microcephaly among newborns in the state of Pernambuco, northeastern Brazil.

As of 17 November, a total of 399 cases of microcephaly were being investigated in seven states in the northeast of Brazil. Most of the cases were registered in Pernambuco state (268). Other states that reported microcephaly cases are Sergipe (44), Rio Grande do Norte (39), Paraiba (21), Piaui (10), Ceara (9) and Bahia (8).

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