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On 4 January 2016, the Ministry of Health (MoH) of Brazil provided PAHO/WHO with an epidemiological report regarding the increase of microcephaly cases in the country.

As of 2 January, 3,174 suspected cases of microcephaly, including 38 deaths, had been identified at the national level. The cases are distributed across 684 municipalities of 21 federal units. The Northeastern region continues to report the highest number of suspected cases.

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