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Full Santo Domingo Zika Sequences - Broad Institute


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LOCUS       KY014300               10659 bp    RNA     linear   VRL 21-OCT-2016
DEFINITION  Zika virus isolate Zika virus/H.sapiens-wt/DOM/2016/BB-0208-SER
            polyprotein gene, complete cds.
ACCESSION   KY014300
VERSION     KY014300.1
DBLINK      BioProject: PRJNA344504
            BioSample: SAMN05861584
KEYWORDS    .
SOURCE      Zika virus
  ORGANISM  Zika virus
            Viruses; ssRNA viruses; ssRNA positive-strand viruses, no DNA
            stage; Flaviviridae; Flavivirus.
REFERENCE   1  (bases 1 to 10659)
  AUTHORS   Baniecki,M.L., Barnes,K.G., Bosch,I., Freije,C.A., Gehrke,L.,
            Gladden-Young,A.D., Gnirke,A., Luo,C.Y., MacInnis,B.,
            Matranga,C.B., Metsky,H.C., Park,D.J., Qu,J., Sabeti,P.C.,
            Tomkins-Tinch,C.H., West,K.L., Winnicki,S., Wohl,S. and
            Yozwiak,N.L.
  TITLE     Direct Submission
  JOURNAL   Submitted (20-OCT-2016) Viral Genomics, Infectious Disease Program
            (Infectious Disease Initiative), Broad Institute, 75 Ames St,
            Cambridge, MA 02142, USA
COMMENT     ##Assembly-Data-START##
            Assembly Method       :: github.com/broadinstitute/viral-ngs v.
                                     v1.12.0-51-g8588fdb
            Assembly Name         :: DOM_2016_BB-0208_SER-1
            Coverage              :: 141x
            Sequencing Technology :: Illumina; Swift LC
            ##Assembly-Data-END##
FEATURES             Location/Qualifiers
     source          1..10659
                     /organism="Zika virus"
                     /mol_type="genomic RNA"
                     /isolate="Zika virus/H.sapiens-wt/DOM/2016/BB-0208-SER"
                     /isolation_source="serum"
                     /host="Homo sapiens"
                     /db_xref="taxon:64320"
                     /country="Dominican Republic: Santo Domingo"
                     /collection_date="20-Apr-2016"
                     /collected_by="Hospital General de la Plaza de la Salud,
                     Santo Domingo, Dominican Republic"
     5'UTR           <1..88
     CDS             89..10360
                     /note="contains structural and nonstructural proteins"
                     /codon_start=1
                     /product="polyprotein"
                     /protein_id="AOY08521.1"
                     /translation="MKNPKKKSGGFRIVNMLKRGVARVSPFGGLKRLPAGLLLGHGPI
                     RMVLAILAFLRFTAIKPSLGLINRWGSVGKKEAMEIIKKFKKDLAAMLRIINARKEKK
                     RRGADTSVGIVGLLLTTAMAAEVTRRGSAYYMYLDRNDAGEAISFPTTLGMNKCYIQI
                     MDLGHMCDATMSYECPMLDEGVEPDDVDCWCNTTSTWVVYGTCHHKKGEARRSRRAVT
                     LPSHSTRKLQTRSQTWLESREYTKHLIRVENWIFRNPGFALAAAAIAWLLGSSTSQKV
                     IYLVMILLIAPAYSIRCIGVSNRDFVEGMSGGTWVDVVLEHGGCVTVMAQDKPTVDIE
                     LVTTTVSNMAEVRSYCYEASISDMASDSRCPTQGEAYLDKQSDTQYVCKRTLVDRGWG
                     NGCGLFGKGSLVTCAKFACSKKMTGKSIQPENLEYRIMLSVHGSQHSGMIVNDTGHET
                     DENRAKVEITPNSPRAEATLGGFGSLGLDCEPRTGLDFSDLYYLTMNNKHWLVHKEWF
                     HDIPLPWHAGADTGTPHWNNKEALVEFKDAHAKRQTVVVLGSQEGAVHTALAGALEAE
                     MDGAKGRLSSGHLKCRLKMDKLRLKGVSYSLCTAAFTFTKIPAETLHGTVTVEVQYAG
                     TDGPCKVPAQMAVDMQTLTPVGRLITANPVITESTENSKMMLELDPPFGDSYIVIGVG
                     EKKITHHWHRSGSTIGKAFEATVRGAKRMAVLGDTAWDFGSVGGALNSLGKGIHQIFG
                     AAFKSLFGGMSWFSQILIGTLLMWLGLNTKNGSISLMCLALGGVLIFLSTAVSADVGC
                     SVDFSKKETRCGTGVFVYNDVEAWRDRYKYHPDSPRRLAAAVKQAWEDGICGISSVSR
                     MENIMWRSVEGELNAILEENGVQLTVVVGSVKNPMWRGPQRLPVPVNELPHGWKAWGK
                     SYFVRAAKTNNSFVVDGDTLKECPLKHRAWNSFLVEDHGFGVFHTSVWLKVREDYSLE
                     CDPAVIGTAVKGKEAVHSDLGYWIESEKNDTWRLKRAHLIEMKTCEWPKSHTLWTDGI
                     EESDLIIPKSLAGPLSHHNTREGYRTQMKGPWHSEELEIRFEECPGTKVHVEETCGTR
                     GPSLRSTTASGRVIEEWCCRECTMPPLSFRAKDGCWYGMEIRPRKEPESNLVRSVVTA
                     GSTDHMDHFSLGVLVILLMVQEGLKKRMTTKIIISTSMAVLVAMILGGFSMSDLAKLA
                     ILMGATFAEMNTGGDVAHLALIAAFKVRPALLVSFIFRANWTPRESMLLALASCLLQT
                     AISALEGDLMVLINGFALAWLAIRAMVVPRTDNITLAILAALTPLARGTLLVAWRAGL
                     ATCGGFMLLSLKGKGSVKKNLPFVMALGLTAVRLVDPINVVGLLLLTRSGKRSWPPSE
                     VLTAVGLICALAGGFAKADIEMAGPMAAVGLLIVSYVVSGKSVDMYIERAGDITWEKD
                     AEVTGNSPRLDVALDESGDFSLVEDDGPPMREIILKVVLMTICGMNPIAIPFAAGAWY
                     VYVKTGKRSGALWDVPAPKEVKKGETTDGVYRVMTRRLLGSTQVGVGVMQEGVFHTMW
                     HVTKGSALRSGEGRLDPYWGDVKQDLVSYCGPWKLDAAWDGHSEVQLLAVPPGERARN
                     IQTLPGIFKTKDGDIGAVALDYPAGTSGSPILDKCGRVIGLYGNGVVIKNGSYVSAIT
                     QGRREEETPVECFEPSMLKKKQLTVLDLHPGAGKTRRVLPEIVREAIKTRLRTVILAP
                     TRVVAAEMEEALRGLPVRYMTTAVNVTHSGTEIVDLMCHATFTSRLLQPIRVPNYNLY
                     IMDEAHFTDPSSIAARGYISTRVEMGEAAAIFMTATPPGTRDAFPDSNSPIMDTEVEV
                     PERAWSSGFDWVTDHSGKTVWFVPSVRNGNEIAACLTKAGKRVIQLSRKTFETEFQKT
                     KHQEWDFVVTTDISEMGANFKADRVIDSRRCLKPVILDGERVILAGPMPVTHASAAQR
                     RGRIGRNPNKPGDEYLYGGGCAETDEDHAHWLEARMLLDNIYLQDGLIASLYRPEADK
                     VAAIEGEFKLRTEQRKTFVELMKRGDLPVWLAYQVASAGITYTDRRWCFDGTTNNTIM
                     EDSVPAEVWTRHGEKRVLKPRWMDARVCSDHAALKSFKEFAAGKRGAAFGVMEALGTL
                     PGHMTERFQEAIDNLAVLMRAETGSRPYKAAAAQLPETLETIMLLGLLGTVSLGIFFV
                     LMRNKGIGKMGFGMVTLGASAWLMWLSEIEPARIACVLIVVFLLLVVLIPEPEKQRSP
                     QDNQMAIIIMVAVGLLGLITANELGWLERTKSDLSHLMGRREEGATIGFSMDIDLRPA
                     SAWAIYAALTTFITPAVQHAVTTSYNNYSLMAMATQAGVLFGMGKGMPFYAWDFGVPL
                     LMIGCYSQLTPLTLIVAIILLVAHYMYLIPGLQAAAARAAQKRTAAGIMKNPVVDGIV
                     VTDIDTMTIDPQVEKKMGQVLLIAVAVSSAILSRTAWGWGEAGALITAATSTLWEGSP
                     NKYWNSSTATSLCNIFRGSYLAGASLIYTVTRNAGLVKRRGGGTGETLGEKWKARLNQ
                     MSALEFYSYKKSGITEVCREEARRALKDGVATGGHAVSRGSAKLRWLVERGYLQPYGK
                     VIDLGCGRGGWSYYAATIRKVQEVKGYTKGGPGHEEPVLVQSYGWNIVRLKSGVDVFH
                     MAAEPCDTLLCDIGESSSSPEVEEARTLRVLSMVGDWLEKRPGAFCIKVLCPYTSTMM
                     ETLERLQRRYGGGLVRVPLSRNSTHEMYWVSGAKSNTIKSVSTTSQLLLGRMDGPRRP
                     VKYEEDVNLGSGTRAVVSCAEAPNMKIIGNRIERIRSEHAETWFFDENHPYRTWAYHG
                     SYEAPTQGSASSLVNGVVRLLSKPWDVVTGVTGIAMTDTTPYGQQRVFKEKVDTRVPD
                     PQEGTRQVMSMVSSWLWKELGKHKRPRVCTKEEFINKVRSNAALGAIFEEEKEWKTAV
                     EAVNDPRFWALVDKEREHHLRGECQSCVYNMMGKREKKQGEFGKAKGSRAIWYMWLGA
                     RFLEFEALGFLNEDHWMGRENSGGGVEGLGLQRLGYVLEEMSRIPGGRMYADDTAGWD
                     TRISRFDLENEALITNQMEKGHRALALAIIKYTYQNKVVKVLRPAEKGKTVMDIISRQ
                     DQRGSGQVVTYALNTFTNLVVQLIRNMEAEEVLEMQDLWLLRRSEKVTNWLQSNGWDR
                     LKRMAVSGDDCVVKPIDDRFAHALRFLNDMGKVRKDTQEWKPSTGWDNWEEVPFCSHH
                     FNKLHLKDGRSIVVPCRHQDELIGRARVSPGAGWSIRETACLAKSYAQMWQLLYFHRR
                     DLRLMANAICSSVPVDWVPTGRTTWSIHGKGEWMTIEDMLVVWNRVWIEENDHMEDKT
                     PVTKWTDIPYLGKREDLWCGSLIGHRPRTTWAENIKNTVNMVRRIIGEEEKYMDYLST
                     QVRYLGEEGSTPGVL"
     3'UTR           10361..10659
ORIGIN      
        1 tcagactgcg acagttcgag tttgaagcga aagctagcaa cagtatcaac aggttttatt
       61 ttggatttgg aaacgagagt ttctggtcat gaaaaaccca aaaaagaaat ccggaggatt
      121 ccggattgtc aatatgctaa aacgcggagt agcccgtgtg agcccctttg ggggcttgaa
      181 gaggctgcca gccggacttc tgctgggtca tgggcccatc aggatggtct tggcgattct
      241 agcctttttg agattcacgg caatcaagcc atcactgggt ctcatcaata gatggggttc
      301 agtggggaaa aaagaggcta tggaaataat aaagaagttc aagaaagatc tggctgccat
      361 gctgagaata atcaatgcta ggaaggagaa gaagagacga ggcgcagata ctagtgtcgg
      421 aattgttggc ctcctgctga ccacagctat ggcagcggag gtcactagac gtgggagtgc
      481 atactacatg tacttggaca gaaacgatgc tggggaggcc atatcttttc caaccacatt
      541 ggggatgaat aagtgttata tacagatcat ggatcttgga cacatgtgtg atgccaccat
      601 gagctatgaa tgccctatgc tggatgaggg ggtggaacca gatgacgtcg attgttggtg
      661 caacacgacg tcaacttggg ttgtgtacgg aacctgccat cacaaaaaag gtgaagcacg
      721 gagatctaga agagctgtga cgctcccctc ccattccact aggaagctgc aaacgcggtc
      781 gcaaacctgg ttggaatcaa gagaatacac aaagcacttg attagagtcg aaaattggat
      841 attcaggaac cctggcttcg cgttagcagc agctgccatc gcttggcttt tgggaagctc
      901 aacgagccaa aaagtcatat acttggtcat gatactgctg attgccccgg catacagcat
      961 caggtgcata ggagtcagca atagggactt tgtggaaggt atgtcaggtg ggacttgggt
     1021 tgatgttgtc ttggaacatg gaggttgtgt caccgtaatg gcacaggaca aaccgactgt
     1081 cgacatagag ctggttacaa caacagtcag caacatggcg gaggtgagat cctactgcta
     1141 tgaggcatca atatcagaca tggcttcgga cagccgctgc ccaacacaag gtgaagccta
     1201 ccttgacaag caatcagaca ctcaatatgt ctgcaaaaga acgttagtgg acagaggctg
     1261 gggaaatgga tgtggacttt ttggcaaagg gagcctggtg acatgcgcta agtttgcatg
     1321 ctccaagaaa atgaccggga agagcatcca gccagagaat ctggagtacc ggataatgct
     1381 gtcagttcat ggctcccagc acagtgggat gatcgttaat gacacaggac atgaaactga
     1441 tgagaataga gcgaaggttg agataacgcc caattcacca agagccgaag ccaccctggg
     1501 gggttttgga agcctaggac ttgattgtga accgaggaca ggccttgact tttcagattt
     1561 gtattacttg actatgaata acaagcactg gttggttcac aaggagtggt tccacgacat
     1621 tccattacct tggcacgctg gggcagacac cggaactcca cactggaaca acaaagaagc
     1681 actggtagag ttcaaggacg cacatgccaa aaggcaaact gtcgtggttc tagggagtca
     1741 agaaggagca gttcacacgg cccttgctgg agctctggag gctgagatgg atggtgcaaa
     1801 gggaaggctg tcctctggcc acttgaaatg tcgcctgaaa atggataaac ttagattgaa
     1861 gggcgtgtca tactccttgt gtaccgcagc gttcacattc accaagatcc cggctgaaac
     1921 actgcacggg acagtcacag tggaggtaca gtacgcaggg acagatggac cttgcaaggt
     1981 tccagctcag atggcggtgg acatgcaaac tctgacccca gttgggaggt tgataaccgc
     2041 caaccccgta atcactgaaa gcactgagaa ctctaagatg atgctggaac ttgatccacc
     2101 atttggggac tcttacattg tcataggagt cggggagaag aagatcaccc accactggca
     2161 caggagtggc agcaccattg gaaaagcatt tgaagccact gtgagaggtg ccaagagaat
     2221 ggcagtcttg ggagacacag cctgggactt tggatcagtt ggaggcgctc tcaactcatt
     2281 gggcaagggc atccatcaaa tttttggagc agctttcaaa tcattgtttg gaggaatgtc
     2341 ctggttctca caaatcctca ttggaacgtt gctgatgtgg ttgggtctga acacaaagaa
     2401 tggatctatt tccctcatgt gcttggcctt agggggagtg ttgatcttct tatccacagc
     2461 cgtctctgct gatgtggggt gctcggtgga cttctcaaag aaggagacga gatgcggtac
     2521 aggggtgttc gtctataacg acgttgaagc ctggagggac aggtacaagt accatcctga
     2581 ctccccccgt agattggcag cagcagtcaa gcaagcctgg gaagatggta tctgcgggat
     2641 ctcctctgtt tcaagaatgg aaaacatcat gtggagatca gtagaagggg agctcaatgc
     2701 aatcctggaa gagaatggag ttcaactgac ggtcgttgtg ggatctgtaa aaaaccccat
     2761 gtggagaggt ccacagagat tgcccgtgcc tgtgaacgag ctgccccacg gctggaaggc
     2821 ttgggggaaa tcgtacttcg ttagagcagc aaagacaaat aacagctttg tcgtggatgg
     2881 tgacacactg aaggaatgcc cactcaaaca tagagcatgg aacagctttc ttgtggagga
     2941 tcatgggttc ggggtatttc acactagtgt ctggctcaag gttagagaag attattcatt
     3001 agagtgtgat ccagccgtta ttggaacagc tgttaaggga aaggaggctg tacacagtga
     3061 tctaggctac tggattgaga gtgagaagaa tgacacatgg aggctgaaga gggcccatct
     3121 gatcgagatg aaaacatgtg aatggccaaa gtcccacaca ttgtggacag atggaataga
     3181 agagagtgat ctgatcatac ccaagtcttt agctgggcca ctcagccatc acaataccag
     3241 agagggctac aggacccaaa tgaaagggcc atggcacagt gaagagcttg aaattcggtt
     3301 tgaggaatgc ccaggcacta aggtccacgt ggaggaaaca tgtggaacaa gaggaccatc
     3361 tctgagatca accactgcaa gcggaagggt gatcgaggaa tggtgctgca gggagtgcac
     3421 aatgccccca ctgtcgttcc gggctaaaga tggctgttgg tatggaatgg agataaggcc
     3481 caggaaagaa ccagaaagca acttagtaag gtcagtggtg actgcaggat caactgatca
     3541 catggatcac ttctcccttg gagtgcttgt gattctgctc atggtgcagg aagggctgaa
     3601 gaagagaatg accacaaaga tcatcataag cacatcaatg gcagtgctgg tagctatgat
     3661 cctgggagga ttttcaatga gcgacctggc taagcttgca attttgatgg gcgccacctt
     3721 cgcggaaatg aacactggag gagatgtagc tcatctggcg ctgatagcgg cattcaaagt
     3781 cagaccagcg ttgctggtat ctttcatctt cagagctaat tggacacccc gtgaaagcat
     3841 gctgctggcc ttggcctcgt gtcttttgca aactgcgatc tccgccttgg aaggcgacct
     3901 gatggttctc atcaatggtt ttgctttggc ctggttggca atacgagcga tggttgttcc
     3961 acgcactgat aacatcacct tggcaatcct ggctgctctg acaccactgg cccggggcac
     4021 actgcttgtg gcgtggagag caggccttgc tacttgcggg gggtttatgc tcctctctct
     4081 gaagggaaaa ggcagtgtga agaagaactt accatttgtc atggccctgg gactaaccgc
     4141 tgtgaggctg gtcgacccca tcaacgtggt gggactgctg ttgctcacaa ggagtgggaa
     4201 gcggagctgg ccccctagcg aagtactcac agctgttggc ctgatatgcg cattggctgg
     4261 agggttcgcc aaggcagata tagagatggc tgggcccatg gccgcggtcg gtctgctaat
     4321 tgtcagttac gtggtctcag gaaagagtgt ggacatgtac attgaaagag caggtgacat
     4381 cacatgggaa aaagatgcgg aagtcactgg aaacagtccc cggctcgatg tggcgctaga
     4441 tgagagtggt gatttctccc tggtggagga tgacggtccc cccatgagag agatcatact
     4501 caaggtggtc ctgatgacca tctgtggcat gaacccaata gccataccct ttgcagctgg
     4561 agcgtggtac gtatacgtga agactggaaa aaggagtggt gctctatggg atgtgcctgc
     4621 tcccaaggaa gtaaaaaagg gggagaccac agatggagtg tacagagtaa tgactcgtag
     4681 actgctaggt tcaacacaag ttggagtggg agttatgcaa gagggggtct ttcacactat
     4741 gtggcacgtc acaaaaggat ccgcgctgag aagcggtgaa gggagacttg atccatactg
     4801 gggagatgtc aagcaggatc tggtgtcata ctgtggtcca tggaagctag atgccgcctg
     4861 ggacgggcac agcgaggtgc agctcttggc cgtgcccccc ggagagagag cgaggaacat
     4921 ccagactctg cccggaatat ttaagacaaa ggatggggac attggagcgg ttgcgctgga
     4981 ttacccagca ggaacttcag gatctccaat cctagacaag tgtgggagag tgataggact
     5041 ttatggcaat ggggtcgtga tcaaaaatgg gagttatgtt agtgccatca cccaagggag
     5101 gagggaggaa gagactcctg ttgagtgctt cgagccttcg atgctgaaga agaagcagct
     5161 aactgtctta gacttgcatc ctggagctgg gaaaaccagg agagttcttc ctgaaatagt
     5221 ccgtgaagct ataaaaacaa gactccgtac tgtgatctta gctccaacca gggttgtcgc
     5281 tgctgaaatg gaggaagccc ttagagggct tccagtgcgt tatatgacaa cagcagtcaa
     5341 tgtcacccat tctggaacag aaatcgtcga cttaatgtgc catgccacct tcacttcacg
     5401 tctactacag ccaatcagag tccccaacta taatctgtat attatggatg aggcccactt
     5461 cacagatccc tcaagtatag cagcaagagg atacatttca acaagggttg agatgggcga
     5521 ggcggctgcc atcttcatga ccgccacgcc accaggaacc cgtgacgcat ttccggactc
     5581 caactcacca attatggaca ccgaagtgga agtcccagag agagcctgga gctcaggctt
     5641 tgattgggtg acggatcatt ctggaaaaac agtttggttt gttccaagcg tgaggaacgg
     5701 caatgagatc gcagcttgtc tgacaaaggc tggaaaacgg gtcatacagc tcagcagaaa
     5761 gacttttgag acagagttcc agaaaacaaa acatcaagag tgggactttg tcgtgacaac
     5821 cgacatttca gagatgggcg ccaactttaa agctgaccgt gtcatagatt ccaggagatg
     5881 cctaaagccg gtcatacttg atggcgagag agtcattctg gctggaccca tgcctgtcac
     5941 acatgccagc gctgcccaga ggagggggcg cataggcagg aatcccaaca aacctggaga
     6001 tgagtatctg tatggaggtg ggtgcgcaga gactgacgaa gaccatgcac actggcttga
     6061 agcaagaatg ctccttgaca acatttacct ccaagatggc ctcatagcct cgctctatcg
     6121 acctgaggcc gacaaagtag cagccattga gggagagttc aagcttagga cggagcaaag
     6181 gaagaccttt gtggaactca tgaaaagagg agatcttcct gtttggctgg cctatcaggt
     6241 tgcatctgcc ggaataactt acacagatag aagatggtgc tttgatggca cgaccaacaa
     6301 caccataatg gaagacagtg tgccggcaga ggtgtggacc agacacggag agaaaagagt
     6361 gctcaaaccg aggtggatgg acgccagagt ttgttcagat catgcggccc tgaagtcatt
     6421 caaggagttt gccgctggga aaagaggagc ggcttttgga gtgatggaag ccctgggaac
     6481 actgccagga cacatgacag agagattcca ggaagccatt gacaacctcg ctgtgctcat
     6541 gcgggcagag actggaagca ggccttacaa agccgcggcg gcccaattgc cggagaccct
     6601 agagaccatt atgcttttgg ggttgctggg aacagtctcg ctgggaatct ttttcgtctt
     6661 gatgaggaac aagggcatag ggaagatggg ctttggaatg gtgactcttg gggccagcgc
     6721 atggctcatg tggctctcgg aaattgagcc agccagaatt gcatgtgtcc tcattgttgt
     6781 gttcctattg ctggtggtgc tcatacctga gccagaaaag caaagatctc cccaggacaa
     6841 ccaaatggca atcatcatca tggtagcagt aggtcttctg ggcttgatca ccgccaatga
     6901 actcggatgg ttggagagaa caaagagtga cctaagccat ctaatgggaa ggagagagga
     6961 gggagcaacc ataggattct caatggacat tgacctgcgg ccagcctcag cttgggccat
     7021 ctatgctgcc ttgacaactt tcattacccc agccgtccaa catgcagtga ccacttcata
     7081 caacaactac tccttaatgg cgatggccac gcaagctgga gtgttgtttg gtatgggcaa
     7141 agggatgcca ttctacgcat gggactttgg agtcccgctg ctaatgatag gttgctattc
     7201 acaattaaca cccctgaccc taatagtggc catcattttg ctcgtggcgc actacatgta
     7261 cttgatccca gggctgcagg ctgcagctgc gcgtgctgcc cagaagagaa cggcagctgg
     7321 catcatgaag aaccctgttg tggatggaat agtggtgact gacattgaca caatgacaat
     7381 tgacccccaa gtggagaaaa agatgggaca ggtgctactc atagcagtag ccgtctccag
     7441 cgccatactg tcgcggaccg cctgggggtg gggggaggct ggggccctga tcacagccgc
     7501 aacttccact ttgtgggaag gctctccgaa caagtactgg aactcctcta cagccacttc
     7561 actgtgtaac atttttaggg gaagttactt ggctggagct tctctaatct acacagtaac
     7621 aagaaacgct ggcttggtca agagacgtgg gggtggaaca ggagagaccc tgggagagaa
     7681 atggaaggcc cgcttgaacc agatgtcggc cctggagttc tactcctaca aaaagtcagg
     7741 catcaccgag gtgtgcagag aagaggcccg ccgcgccctc aaggacggtg tggcaacggg
     7801 aggccatgct gtgtcccgag gaagtgcaaa gctgagatgg ttggtggagc ggggatacct
     7861 gcagccctat ggaaaggtca ttgatcttgg atgtggcaga gggggctgga gttactacgc
     7921 cgccaccatc cgcaaagttc aagaagtgaa aggatacaca aaaggaggcc ctggtcatga
     7981 agaacccgtg ttggtgcaaa gctatgggtg gaacatagtc cgtctcaaga gtggggtgga
     8041 cgtctttcat atggcggctg agccgtgtga cacgttgctg tgtgacatag gtgagtcatc
     8101 atctagtcct gaagtggaag aagcacggac gctcagagtc ctctccatgg tgggggattg
     8161 gcttgaaaaa agaccaggag ccttttgtat aaaagtgttg tgcccataca ccagcactat
     8221 gatggaaacc ctggagcgac tgcagcgtag gtatggggga ggactggtca gagtgccact
     8281 ctcccgcaac tctacacatg agatgtactg ggtctctgga gcgaaaagca acaccataaa
     8341 aagtgtgtcc accacgagcc agctcctctt ggggcgcatg gacgggccta ggaggccagt
     8401 gaaatatgag gaggatgtga atctcggctc tggcacgcgg gctgtggtaa gctgcgctga
     8461 agctcccaac atgaagatca ttggtaaccg cattgaaagg atccgcagtg agcacgcgga
     8521 aacgtggttc tttgacgaga accacccata taggacatgg gcttaccatg gaagctatga
     8581 ggcccccaca caagggtcag catcctctct agtaaacggg gttgtcaggc tcctgtcaaa
     8641 accctgggat gtggtgactg gagtcacagg aatagccatg accgacacca caccgtatgg
     8701 tcagcaaaga gttttcaagg aaaaagtgga cactagggtg ccagaccccc aagaaggcac
     8761 tcgtcaggtt atgagcatgg tctcttcctg gttgtggaaa gagctaggca aacacaaacg
     8821 gccacgagtc tgtaccaaag aagagttcat caacaaggtt cgtagcaatg cagcattagg
     8881 ggcaatattt gaagaggaaa aagagtggaa gactgcagtg gaagctgtga acgatccaag
     8941 gttctgggct ctagtggaca aggaaagaga gcaccacctg agaggagagt gccagagttg
     9001 tgtgtacaac atgatgggaa aaagagaaaa gaaacaaggg gaatttggaa aggccaaggg
     9061 cagccgcgcc atctggtata tgtggctagg ggctagattt ctagagttcg aagcccttgg
     9121 attcttgaac gaggatcact ggatggggag agagaactca ggaggtggtg ttgaagggct
     9181 gggattacaa agactcggat atgtcctaga agagatgagt cgcataccag gaggaaggat
     9241 gtatgcagat gacactgctg gctgggatac ccgcatcagc aggtttgatc tagagaatga
     9301 agctctaatc accaaccaaa tggagaaagg gcacagggcc ttggcattgg ccataatcaa
     9361 gtacacatac caaaacaaag tggtaaaggt ccttagacca gctgaaaaag ggaaaacagt
     9421 tatggacatt atttcgagac aagaccaaag ggggagcgga caagttgtca cttacgctct
     9481 taacacattt accaacctag tggtgcaact cattcggaat atggaggctg aggaagttct
     9541 agagatgcaa gacttgtggc tgctgcggag gtcagagaaa gtgaccaact ggttgcagag
     9601 caacggatgg gataggctca aacgaatggc agtcagtgga gatgattgcg ttgtgaagcc
     9661 aattgatgat aggtttgcac atgccctcag gttcttgaat gatatgggaa aagttaggaa
     9721 ggacacacaa gagtggaaac cctcaactgg atgggacaac tgggaagaag ttccgttttg
     9781 ctcccaccac ttcaacaagc tccatctcaa ggacgggagg tccattgtgg ttccctgccg
     9841 ccaccaagat gaactgattg gccgggcccg cgtctctcca ggggcgggat ggagcatccg
     9901 ggagactgct tgcctagcaa aatcatatgc gcaaatgtgg cagctccttt atttccacag
     9961 aagggacctc cgactgatgg ccaatgccat ttgttcatct gtgccagttg actgggttcc
    10021 aactgggaga actacctggt caatccatgg aaagggagaa tggatgacca ttgaagacat
    10081 gcttgtggtg tggaacagag tgtggattga ggagaacgac cacatggaag acaagacccc
    10141 agttacgaaa tggacagaca ttccctattt gggaaaaagg gaagacttgt ggtgtggatc
    10201 tctcataggg cacagaccgc gcaccacctg ggctgagaac attaaaaaca cagtcaacat
    10261 ggtgcgcagg atcataggtg aggaagaaaa gtacatggac tacctatcca cccaagttcg
    10321 ctacttgggt gaagaagggt ctacacctgg agtgctgtaa gcaccaatct taatgttgtc
    10381 aggcctgcta gtcagccaca gctcggggaa agctgtgcag cctgtgaccc ccccaggaga
    10441 agctgggaaa ccaagcctat agtcaggccg agaacgccat ggcacggaag aagccatgct
    10501 gcctgtgagc ccctcagagg acactgagtc aaaaaacccc acgcgcttgg aggcgcagga
    10561 tgggaaaaga aggtggcgac cttccccacc cttcaatctg gggcctgaac tggagatcag
    10621 ctgtggatct ccagaagagg gactagtggt tagaggaga
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Sequences producing significant alignments:

Select:AllNone Selected:0

Sequences producing significant alignments:
Select for downloading or viewing reports Description Max score Total score Query cover E value Ident Accession
18525 18525 100% 0.0 100% KY014300.1
18471 18471 100% 0.0 99% KY014304.1
18465 18465 100% 0.0 99% KU853013.1
18465 18465 100% 0.0 99% KU853012.1
18462 18462 100% 0.0 99% KY014295.1
18462 18462 100% 0.0 99% LC190723.1
18462 18462 100% 0.0 99% KX842449.2
18456 18456 100% 0.0 99% KY014321.1
18453 18453 100% 0.0 99% KX673530.1
18447 18447 100% 0.0 99% KY014323.1
18447 18447 100% 0.0 99% KX922703.1
18447 18447 100% 0.0 99% KX838905.2
18447 18447 100% 0.0 99% KX832731.1
18446 18446 100% 0.0 99% KX922706.1
18444 18444 100% 0.0 99% KX922707.1
18444 18444 100% 0.0 99% KX922704.1
18438 18438 100% 0.0 99% KY014322.1
18438 18438 100% 0.0 99% KY014314.1
18438 18438 100% 0.0 99% KX838906.2
18438 18438 100% 0.0 99% KX838904.2
18435 18435 100% 0.0 99% KY014324.1
18435 18435 100% 0.0 99% KY014316.1
18428 18428 100% 0.0 99% KX922705.1
18420 18420 100% 0.0 99% KX922708.1
18417 18417 100% 0.0 99% KY014299.1
18375 18375 100% 0.0 99% KX447510.1
18372 18372 100% 0.0 99% KX280026.1
18366 18366 100% 0.0 99% KX447512.1
18366 18366 100% 0.0 99% KX369547.1
18366 18366 100% 0.0 99% KU509998.3
18363 18363 100% 0.0 99% KJ776791.2
18363 18363 100% 0.0 99% KX447509.1
18363 18363 100% 0.0 99% KU991811.1
18363 18363 100% 0.0 99% KU729217.2
18357 18357 100% 0.0 99% KX447513.1
18357 18357 100% 0.0 99% KX051563.1
18354 18354 100% 0.0 99% KX811222.1
18354 18354 100% 0.0 99% KX197205.1
18354 18354 100% 0.0 99% KX447515.1
18354 18354 100% 0.0 99% KX447511.1
18354 18354 100% 0.0 99% KU527068.1
18354 18354 100% 0.0 99% KU321639.1
18348 18348 100% 0.0 99% KX879604.1
18348 18348 100% 0.0 99% KX447514.1
18345 18345 100% 0.0 99% KX447516.1
18345 18345 100% 0.0 99% KU729218.1
18345 18345 100% 0.0 99% KU707826.1
18345 18345 100% 0.0 99% KU365779.1
18339 18339 100% 0.0 99% KX879603.1
18339 18339 100% 0.0 99% KX262887.1
18339 18339 100% 0.0 99% KX197192.1
18339 18339 100% 0.0 99% KU926310.1
18339 18339 100% 0.0 99% KU926309.1
18336 18336 100% 0.0 99% KU940228.1
18330 18330 100% 0.0 99% KX694534.1
18330 18330 100% 0.0 99% KX198135.1
18330 18330 100% 0.0 99% KU501217.1
18330 18330 100% 0.0 99% KU365780.1
18327 18327 100% 0.0 99% KY014303.1
18327 18327 100% 0.0 99% KU647676.1
18327 18327 100% 0.0 99% KU501216.1
18327 18327 100% 0.0 99% KU365777.1
18321 18321 100% 0.0 99% KY014297.1
18321 18321 100% 0.0 99% KX447517.1
18321 18321 100% 0.0 99% KU758877.1
18321 18321 100% 0.0 99% KX247646.1
18321 18321 100% 0.0 99% KX156776.1
18318 18318 100% 0.0 99% KX520666.1
18318 18318 100% 0.0 99% KX156774.1
18318 18318 99% 0.0 99% KU497555.1
18314 18314 100% 0.0 99% KY014327.1
18312 18312 100% 0.0 99% KU820897.5
18312 18312 100% 0.0 99% KX247632.1
18312 18312 100% 0.0 99% KX156775.1
18312 18312 100% 0.0 99% KX087102.1
18312 18312 100% 0.0 99% KU365778.1
18312 18312 100% 0.0 99% KU312312.1
18309 18309 100% 0.0 99% KY014315.1
18309 18309 100% 0.0 99% KU922960.1
18303 18303 100% 0.0 99% KY014296.1
18303 18303 100% 0.0 99% KX806557.2
18303 18303 100% 0.0 99% KX856011.1
18303 18303 100% 0.0 99% KX548902.1
18303 18303 100% 0.0 99% KX446951.1
18303 18303 100% 0.0 99% KU937936.1
18303 18303 100% 0.0 99% KU922923.1
18303 18303 100% 0.0 99% KU501215.1
18300 18300 100% 0.0 99% KX601168.1
18300 18300 100% 0.0 99% KX446950.1
18300 18300 100% 0.0 99% KX087101.2
18300 18300 100% 0.0 99% KU870645.1
18298 18298 100% 0.0 99% KX893855.1
18294 18294 100% 0.0 99% KX702400.1
18294 18294 100% 0.0 99% KX377337.1
18285 18285 100% 0.0 99% KX766029.1
18285 18285 100% 0.0 99% KU820898.1
18282 18282 100% 0.0 99% KX056898.1
18282 18282 100% 0.0 99% KU955590.1
18278 18278 100% 0.0 99% KX766028.1
18276 18276 100% 0.0 99% KU740184.2
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LOCUS       KY014303               10658 bp    RNA     linear   VRL 21-OCT-2016
DEFINITION  Zika virus isolate Zika virus/H.sapiens-wt/DOM/2016/BB-0127-SER
            polyprotein gene, complete cds.
ACCESSION   KY014303
VERSION     KY014303.1
DBLINK      BioProject: PRJNA344504
            BioSample: SAMN05861583
KEYWORDS    .
SOURCE      Zika virus
  ORGANISM  Zika virus
            Viruses; ssRNA viruses; ssRNA positive-strand viruses, no DNA
            stage; Flaviviridae; Flavivirus.
REFERENCE   1  (bases 1 to 10658)
  AUTHORS   Baniecki,M.L., Barnes,K.G., Bosch,I., Freije,C.A., Gehrke,L.,
            Gladden-Young,A.D., Gnirke,A., Luo,C.Y., MacInnis,B.,
            Matranga,C.B., Metsky,H.C., Park,D.J., Qu,J., Sabeti,P.C.,
            Tomkins-Tinch,C.H., West,K.L., Winnicki,S., Wohl,S. and
            Yozwiak,N.L.
  TITLE     Direct Submission
  JOURNAL   Submitted (20-OCT-2016) Viral Genomics, Infectious Disease Program
            (Infectious Disease Initiative), Broad Institute, 75 Ames St,
            Cambridge, MA 02142, USA
COMMENT     ##Assembly-Data-START##
            Assembly Method       :: github.com/broadinstitute/viral-ngs v.
                                     v1.12.0-51-g8588fdb
            Assembly Name         :: DOM_2016_BB-0127_SER-1
            Coverage              :: 231x
            Sequencing Technology :: Illumina; Swift LC
            ##Assembly-Data-END##
FEATURES             Location/Qualifiers
     source          1..10658
                     /organism="Zika virus"
                     /mol_type="genomic RNA"
                     /isolate="Zika virus/H.sapiens-wt/DOM/2016/BB-0127-SER"
                     /isolation_source="serum"
                     /host="Homo sapiens"
                     /db_xref="taxon:64320"
                     /country="Dominican Republic: Santo Domingo"
                     /collection_date="11-Apr-2016"
                     /collected_by="Hospital General de la Plaza de la Salud,
                     Santo Domingo, Dominican Republic"
     5'UTR           <1..88
     CDS             89..10360
                     /note="contains structural and nonstructural proteins"
                     /codon_start=1
                     /product="polyprotein"
                     /protein_id="AOY08524.1"
                     /translation="MKNPKKKSGGFRIVNMLKRGVARVSPFGGLKRLPAGLLLGHGPI
                     RMVLAILAFLRFTAIKPSLGLINRWGSVGKKEAMEIIKKFKKDLAAMLRIINARKEKK
                     RRGAETSVGIVGLLLTTAMAAEVTRRGSAYYMYLDRNDAGEAISFPTTLGMNKCYIQI
                     MDLGHMCDATMSYECPMLDEGVEPDDVDCWCNTTSTWVVYGTCHHKKGEARRSRRAVT
                     LPSHSTRKLQTRSQTWLESREYTKHLIRVENWIFRNPGFALAAAAIAWLLGSSTSQKV
                     IYLVMILLIAPAYSIRCIGVSNRDFVEGMSGGTWVDVVLEHGGCVTVMAQDKPTVDIE
                     LVTTTVSNMAEVRSYCYEASISDMASDSRCPTQGEAYLDKQSDTQYVCKRTLVDRGWG
                     NGCGLFGKGSLVTCAKFACSKKMTGKSIQPENLEYRIMLSVHGSQHSGMIVNDTGHET
                     DENRAKVEITPNSPRAEATLGGFGSLGLDCEPRTGLDFSDLYYLTMNNKHWLVHKEWF
                     HDIPLPWHAGADTGTPHWNNKEALVEFKDAHAKRQTVVVLGSQEGAVHTALAGALEAE
                     MDGAKGRLSSGHLKCRLKMDKLRLKGVSYSLCTAAFTFTKIPAETLHGTVTVEVQYAG
                     TDGPCKVPAQMAVDMQTLTPVGRLITANPVITESTENSKMMLELDPPFGDSYIVIGVG
                     EKKITHHWHRSGSTIGKAFEATVRGAKRMAVLGDTAWDFGSVGGALNSLGKGIHQIFG
                     AAFKSLFGGMSWFSQILIGTLLMWLGLNTKNGSISLMCLALGGVLIFLSTAVSADVGC
                     SVDFSKKETRCGTGVFVYNDVEAWRDRYKYHPDSPRRLAAAVKQAWEDGICGISSVSR
                     MENIMWRSVEGELNAILEENGVQLTVVVGSVKNPMWRGPQRLPVPVNELPHGWKAWGK
                     SYFVRAAKTNNSFVVDGDTLKECPLKHRAWNSFLVEDHGFGVFHTSVWLKVREDYSLE
                     CDPAVIGTAVKGKEAVHSDLGYWIESEKNDTWRLKRAHLIEMKTCEWPKSHTLWTDGI
                     EESDLIIPKSLAGPLSHHNTREGYRTQMKGPWHSEELEIRFEECPGTKVHVEETCGTR
                     GPSLRSTTASGRVIEEWCCRECTMPPLSFWAKDGCWYGMEIRPRKEPESNLVRSMVTA
                     GSTDHMDHFSLGVLVILLMVQEGLKKRMTTKIIISTSMAVLVAMILGGFSMSDLAKLA
                     ILMGATFAEMNTGGDVAHLALIAAFKVRPALLVSFIFRANWTPRESMLLALASCLLQT
                     AISALEGDLMVLINGFALAWLAIRAMVVPRTDNITLAILAALTPLTRGTLLVAWRAGL
                     ATCGGFMLLSLKGKGSVKKNLPFVMALGLTAVRLVDPINVVGLLLLTRSGKRSWPPSE
                     VLTAVGLICALAGGFAKADIEMAGPMAAVGLLIVSYVVSGKSVDMYIERAGDITWEKD
                     AEVTGNSPRLDVALDESGDFSLVEDDGPPMREIILKVVLMTICGMNPIAIPFAAGAWY
                     VYVKTGKRSGALWDVPAPKEVKKGETTDGVYRVMTRRLLGSTQVGVGVMQEGVFHTMW
                     HVTKGSALRSGEGRLDPYWGDVKQDLVSYCGPWKLDAAWDGHSEVQLLAVPPGERARN
                     IQTLPGIFKTKDGDIGAVALDYPAGTSGSPILDKCGRVIGLYGNGVVIKNGSYVSAIT
                     QGRREEETPVECFEPSMLKKKQLTVLDLHPGAGKTRRVLPEIVREAIKTRLRTVILAP
                     TRVVAAEMEEALRGLPVRYMTTAVNVTHSGTEIVDLMCHATFTSRLLQPIRVPNYNLY
                     IMDEAHFTDPSSIAARGYISTRVEMGEAAAIFMTATPPGTRDAFPDSNSPIMDTEVEV
                     PERAWSSGFDWVTDHSGKTVWFVPSVRNGNEIAACLTKAGKRVIQLSRKTFETEFQKT
                     KHQEWDFVVTTDISEMGANFKADRVIDSRRCLKPVILDGERVILAGPMPVTHASAAQR
                     RGRIGRNPNKPGDEYLYGGGCAETDEDHAHWLEARMLLDNIYLQDGLIASLYRPEADK
                     VAAIEGEFKLRTEQRKTFVELMKRGDLPVWLAYQVASAGITYTDRRWCFDGTTNNTIM
                     EDSVPAEVWTRHGEKRVLKPRWMDARVCSDHAALKSFKEFAAGKRGAAFGVMEALGTL
                     PGHMTERFQEAIDNLAVLMRAETGSRPYKAAAAQLPETLETIMLLGLLGTVSLGIFFV
                     LMRNKGIGKMGFGMVTLGASAWLMWLSEIEPARIACVLIVVFLLLVVLIPEPEKQRSP
                     QDNQMAIIIMVAVGLLGLITANELGWLERTKSDLSHLMGRREEGATIGFSMDIDLRPA
                     SAWAIYAALTTFITPAVQHAVTTSYNNYSLMAMATQAGVLFGMGKGMPFYAWDFGVPL
                     LMIGCYSQLTPLTLIVAIILLVAHYMYLIPGLQAAAARAAQKRTAAGIMKNPVVDGIV
                     VTDIDTMTIDPQVEKKMGQVLLIAVAVSSAILSRTAWGWGEAGALITAATSTLWEGSP
                     NKYWNSSTATSLCNIFRGSYLAGASLIYTVTRNAGLVKRRGGGTGETLGEKWKARLNQ
                     MSALEFYSYKKSGITEVCREEARRALKDGVATGGHAVSRGSAKLRWLVERGYLQPYGK
                     VIDLGCGRGGWSYYAATIRKVQEVKGYTKGGPGHEEPVLVQSYGWNIVRLKSGVDVFH
                     MAAEPCDTLLCDIGESSSSPEVEEARTLRVLSMVGDWLEKRPGAFCIKVLCPYTSTMM
                     ETLERLQRRYGGGLVRVPLSRNSTHEMYWVSGAKSNTIKSVSTTSQLLLGRMDGPRRP
                     VKYEEDVNLGSGTRAVVSCAEAPNMKIIGNRIERIRSEHAETWFFDENHPYRTWAYHG
                     SYEAPTQGSASSLINGVVRLLSKPWDVVTGVTGIAMTDTTPYGQQRVFKEKVDTRVPD
                     PQEGTRQVMSMVSSWLWKELGKHKRPRVCTKEEFINKVRSNAALGAIFEEEKEWKTAV
                     EAVNDPRFWALVDKEREHHLRGECQSCVYNMMGKREKKQGEFGKAKGSRAIWYMWLGA
                     RFLEFEALGFLNEDHWMGRENSGGGVEGLGLQRLGYVLEEMSRIPGGRMYADDTAGWD
                     TRISRFDLENEALITNQMEKGHRALALAIIKYTYQNKVVKVLRPAEKGKTVMDIISRQ
                     DQRGSGQVVTYALNTFTNLVVQLIRNMEAEEVLEMQDLWLLRRSEKVTNWLQSNGWDR
                     LKRMAVSGDDCVVKPIDDRFAHALRFLNDMGKVRKDTQEWKPSTGWDNWEEVPFCSHH
                     FNKLHLKDGRSIVVPCRHQDELIGRARVSPGAGWSIRETACLAKSYAQMWQLLYFHRR
                     DLRLMANAICSSVPVDWVPTGRTTWSIHGKGEWMTTEDMLVVWNRVWIEENDHMEDKT
                     PVAKWTDIPYLGKREDLWCGSLIGHRPRTTWAENIKNTVNMVRRIIGDEEKYMDYLST
                     QVRYLGEEGSTPGVL"
     3'UTR           10361..>10658
ORIGIN      
        1 tcagactgcg acagttcgag tttgaagcga aagctagcaa cagtatcaac aggttttatt
       61 ttggatttgg aaacgagagt ttctggtcat gaaaaaccca aaaaagaaat ccggaggatt
      121 ccggattgtc aatatgctaa aacgcggagt agcccgtgtg agcccctttg ggggcttgaa
      181 gaggctgcca gccggacttc tgctgggtca tgggcccatc aggatggtct tggcgattct
      241 agcctttttg agattcacgg caatcaagcc atcactgggt ctcatcaata gatggggttc
      301 agtggggaaa aaagaggcta tggaaataat aaagaagttc aagaaagatc tggctgccat
      361 gctgagaata atcaatgcta ggaaggagaa gaagagacga ggcgcagaaa ctagtgtcgg
      421 aattgttggc ctcctgctga ccacagctat ggcagcggag gtcactagac gtgggagtgc
      481 atactatatg tacttggaca gaaacgatgc tggggaggcc atatcttttc caaccacatt
      541 ggggatgaat aagtgttata tacagatcat ggatcttgga cacatgtgtg atgccaccat
      601 gagctatgaa tgccctatgc tggatgaggg ggtggaacca gatgacgtcg attgttggtg
      661 caacacgacg tcaacttggg ttgtgtacgg aacctgccat cacaaaaaag gtgaagcacg
      721 gagatctaga agagccgtga cgctcccctc ccattccact aggaagctgc aaacgcggtc
      781 gcaaacctgg ttggaatcaa gagaatacac aaagcacttg attagagtcg aaaattggat
      841 attcaggaac cctggtttcg ctttagcagc agctgccatc gcttggcttt tgggaagctc
      901 aacgagccaa aaagtcatat acttggtcat gatactgctg attgccccgg catacagcat
      961 caggtgcata ggagtcagca atagggactt tgtggaaggt atgtcaggtg ggacttgggt
     1021 tgatgttgtc ttggaacatg gaggttgtgt caccgtaatg gcacaggaca aaccgactgt
     1081 cgacatagag ctggttacaa caacagtcag caacatggcg gaggtaagat cctactgcta
     1141 tgaggcatca atatcagaca tggcttcgga cagccgctgc ccaacacaag gtgaagccta
     1201 ccttgacaag caatcagaca ctcaatatgt ctgcaaaaga acgttagtgg acagaggctg
     1261 gggaaatgga tgtggacttt ttggcaaagg gagcctggtg acatgcgcta agtttgcatg
     1321 ctccaagaaa atgaccggga agagcatcca gccagagaat ctggagtacc ggataatgtt
     1381 gtcagttcat ggctcccagc acagtgggat gatcgttaat gacacaggac atgaaactga
     1441 tgagaataga gcgaaggttg agataacgcc caattcacca agagccgaag ccaccctggg
     1501 gggttttgga agcctaggac ttgattgtga accgaggaca ggccttgact tttcagattt
     1561 gtattacttg acaatgaata acaagcactg gttggttcac aaggagtggt tccacgacat
     1621 tccattacct tggcacgctg gggcagacac cggaactcca cactggaaca acaaagaagc
     1681 actggtagag ttcaaggacg cacatgccaa aaggcaaact gtcgtggttc tagggagtca
     1741 agaaggagca gttcacacgg cccttgctgg agctctggag gctgagatgg atggtgcaaa
     1801 gggaaggctg tcctctggcc acttgaaatg tcgcctgaaa atggataaac ttagattgaa
     1861 gggcgtgtca tactccttgt gtaccgcagc gttcacattc accaagatcc cggctgaaac
     1921 actgcacggg acagtcacag tggaggtaca gtacgcaggg acagatggac cttgcaaggt
     1981 tccagctcag atggcggtgg acatgcaaac tctgacccca gttgggaggt tgataaccgc
     2041 taaccccgta atcactgaaa gcactgagaa ctctaagatg atgctggaac ttgatccacc
     2101 atttggggac tcttacattg tcataggagt cggggagaag aagatcaccc accactggca
     2161 caggagtggc agcaccattg gaaaagcatt tgaagccact gtgagaggtg ccaagagaat
     2221 ggcagtcttg ggagacacag cctgggactt tggatcagtt ggaggcgctc tcaactcatt
     2281 gggcaagggc atccatcaaa tttttggagc agctttcaaa tcattgtttg gaggaatgtc
     2341 ctggttctca caaattctca ttggaacgtt gctgatgtgg ttgggtctga acacaaagaa
     2401 tggatctatt tcccttatgt gcttggcctt agggggagtg ttgatcttct tatccacagc
     2461 cgtctctgct gatgtggggt gctcggtgga cttctcaaag aaggagacga gatgtggtac
     2521 aggggtgttc gtctataacg acgttgaagc ctggagggac aggtacaagt accatcctga
     2581 ctccccccgt agattggcag cagcagtcaa gcaagcctgg gaagatggta tctgcgggat
     2641 ctcctctgtt tcaagaatgg aaaacatcat gtggagatca gtagaagggg agctcaacgc
     2701 aatcctggaa gagaatggag ttcaactgac ggtcgttgtg ggatctgtaa aaaaccccat
     2761 gtggagaggt ccacagagat tgcccgtgcc tgtgaacgag ctgccccacg gctggaaggc
     2821 ttgggggaaa tcgtacttcg tcagagcagc aaagacaaat aacagctttg tcgtggatgg
     2881 tgacacactg aaggaatgcc cactcaaaca tagagcatgg aacagctttc ttgtggagga
     2941 tcatgggttc ggggtatttc acactagtgt ctggctcaag gttagagaag attattcatt
     3001 agagtgtgat ccagccgtta ttggaacagc tgttaaggga aaggaggctg tacacagtga
     3061 tctaggctac tggattgaga gtgagaagaa tgacacatgg aggctgaaga gggcccatct
     3121 gatcgagatg aaaacatgtg aatggccaaa gtcccacaca ttgtggacag atggaataga
     3181 agagagtgat ctgatcatac ccaagtcttt agctgggcca ctcagccatc acaataccag
     3241 agagggctac aggacccaaa tgaaagggcc atggcacagt gaagagcttg aaattcggtt
     3301 tgaggaatgc ccaggcacta aggtccacgt ggaggaaaca tgtggaacaa gaggaccatc
     3361 tctgagatca accactgcaa gcggaagggt gatcgaggaa tggtgctgca gggagtgcac
     3421 aatgccccca ctgtcgttct gggctaaaga tggctgttgg tatggaatgg agataaggcc
     3481 caggaaagaa ccagaaagca acttagtaag gtcaatggtg actgcaggat caactgatca
     3541 catggatcac ttctcccttg gagtgcttgt gattctgctc atggtgcagg aagggctgaa
     3601 gaagagaatg accacaaaga tcatcataag cacatcaatg gcagtgctgg tagctatgat
     3661 cctgggagga ttttcaatga gtgacctggc taagcttgca attttgatgg gtgccacctt
     3721 cgcggaaatg aacactggag gagatgtagc tcatctggcg ctgatagcgg cattcaaagt
     3781 cagaccagcg ttgctggtat ctttcatctt cagagctaat tggacacccc gtgaaagcat
     3841 gctgctggcc ttggcctcgt gtcttttgca aactgcgatc tccgccttgg agggcgacct
     3901 gatggttctc atcaatggtt ttgctttggc ctggttggca atacgagcga tggttgttcc
     3961 acgcactgac aacatcacct tggcaatcct ggctgctctg acaccactga cccggggcac
     4021 actgcttgtg gcgtggagag caggccttgc tacttgcggg gggtttatgc tcctctctct
     4081 gaagggaaaa ggcagtgtga agaagaactt accatttgtc atggccctgg gactaaccgc
     4141 tgtgaggctg gtcgacccca tcaacgtggt gggactgctg ttgctcacaa ggagtgggaa
     4201 gcggagctgg ccccctagcg aagtactcac agctgttggc ctgatatgcg cattggctgg
     4261 agggttcgcc aaggcagata tagagatggc tgggcccatg gccgcggtcg gtctgctaat
     4321 tgtcagttac gtggtctcag gaaagagtgt ggacatgtac attgaaagag caggtgacat
     4381 cacatgggaa aaagatgcgg aagtcactgg aaacagtccc cggctcgacg tggcgctaga
     4441 tgagagtggt gatttctccc tggtggagga tgacggtccc cccatgagag agatcatact
     4501 caaggtggtc ctgatgacca tctgtggcat gaacccaata gccataccct ttgcagctgg
     4561 agcgtggtac gtatacgtga agactggaaa aaggagtggt gctctatggg atgtgcctgc
     4621 tcccaaggaa gtaaaaaagg gggagaccac agatggagtg tacagagtaa tgactcgtag
     4681 actgctaggt tcaacacaag ttggagtggg agttatgcaa gagggggtct ttcacactat
     4741 gtggcacgtc acaaaaggat ccgcgctgag aagcggtgaa gggagacttg atccatactg
     4801 gggagatgtc aagcaggatc tggtgtcata ctgtggtcca tggaagctag atgccgcctg
     4861 ggacgggcac agcgaggtgc agctcttggc cgtgcccccc ggagagagag cgaggaacat
     4921 ccagactctg cccggaatat ttaagacaaa ggatggggac attggagcgg ttgcgctgga
     4981 ttacccagca ggaacttcag gatctccaat cctagacaag tgtgggagag tgataggact
     5041 ttatggcaat ggggtcgtga tcaaaaatgg gagttatgtt agtgccatca cccaagggag
     5101 gagggaggaa gagactcctg ttgagtgctt cgagccttcg atgctgaaga agaagcagct
     5161 aactgtctta gacttgcatc ctggagctgg gaaaaccagg agagttcttc ctgaaatagt
     5221 ccgtgaagcc ataaaaacaa gactccgtac tgtgatctta gctccaacca gggttgtcgc
     5281 tgctgaaatg gaggaagccc ttagagggct tccagtgcgt tatatgacaa cagcagtcaa
     5341 tgtcacccac tctggaacag aaatcgtcga cttaatgtgc catgccacct tcacttcacg
     5401 tctactgcag ccaatcagag tccccaacta taatctgtat attatggatg aggcccactt
     5461 cacagatccc tcaagtatag cagcaagagg atacatttca acaagggttg agatgggcga
     5521 ggcggctgcc atcttcatga ccgccacgcc accaggaacc cgtgacgcat ttccggactc
     5581 caactcacca attatggaca ccgaagtgga agtcccagag agagcctgga gctcaggctt
     5641 tgattgggtg acggatcatt ctggaaaaac agtttggttt gttccaagcg tgaggaacgg
     5701 caatgagatc gcagcttgtc tgacaaaggc tggaaaacgg gtcatacagc tcagcagaaa
     5761 gacttttgag acagagttcc agaaaacaaa acatcaagag tgggactttg tcgtgacaac
     5821 tgacatttca gagatgggcg ccaactttaa agctgaccgt gtcatagatt ccaggagatg
     5881 cctaaagccg gtcatacttg atggcgagag agtcattctg gctggaccca tgcctgtcac
     5941 acatgccagc gctgcccaga ggagggggcg cataggcagg aatcccaata aacctggaga
     6001 tgagtatctg tatggaggtg ggtgcgcaga gactgacgaa gaccatgcac actggcttga
     6061 agcaagaatg ctccttgaca atatttacct ccaagatggc ctcatagcct cgctctatcg
     6121 acctgaggcc gacaaagtag cagccattga gggagagttc aagcttagga cggagcaaag
     6181 gaagaccttt gtggaactca tgaaaagagg agatcttcct gtttggctgg cctatcaggt
     6241 tgcatctgcc ggaataacct acacagatag aagatggtgc tttgatggca cgaccaacaa
     6301 caccataatg gaagacagtg tgccggcaga ggtgtggacc agacacggag agaaaagagt
     6361 gctcaaaccg aggtggatgg acgccagagt ttgttcagat catgcggccc tgaagtcatt
     6421 caaggagttt gccgctggga aaagaggagc ggcttttgga gtgatggaag ccctgggaac
     6481 actgccagga cacatgacag agagattcca ggaagccatt gacaacctcg ctgtgctcat
     6541 gcgggcagag actggaagca ggccttacaa agccgcggcg gcccaattgc cggagaccct
     6601 agagaccatt atgcttttgg ggttgctggg aacagtctcg ctgggaatct ttttcgtctt
     6661 gatgaggaac aagggcatag ggaagatggg ctttggaatg gtgactcttg gggccagcgc
     6721 atggctcatg tggctctcgg aaattgagcc agccagaatt gcatgtgtcc tcattgttgt
     6781 gttcctattg ctggtggtgc tcatacctga gccagaaaag caaagatctc cccaggacaa
     6841 ccaaatggca atcatcatca tggtagcagt aggtcttctg ggcttgatta ccgccaatga
     6901 actcggatgg ttggagagaa caaagagtga cctaagccat ctaatgggaa ggagagagga
     6961 gggggcaacc ataggattct caatggacat tgacttgcgg ccagcctcag cttgggccat
     7021 ctatgctgcc ttgacaactt tcattacccc agccgtccaa catgcagtga ccacttcata
     7081 caacaactac tccttaatgg cgatggccac gcaagctgga gtgttgtttg gtatgggcaa
     7141 agggatgcca ttctacgcat gggactttgg agtcccgctg ctaatgatag gttgctactc
     7201 acaattaaca cccctgaccc taatagtggc catcattttg ctcgtggcgc actacatgta
     7261 cttgatccca gggctgcagg cagcagctgc gcgtgctgcc cagaagagaa cggcagctgg
     7321 catcatgaag aaccctgttg tggatggaat agtggtgact gacattgaca caatgacaat
     7381 tgacccccaa gtggagaaaa agatgggaca ggtgctactc atagcagtag ccgtctccag
     7441 cgccatactg tcgcggaccg cctgggggtg gggggaggct ggggccctga tcacagccgc
     7501 aacttccact ttgtgggaag gctctccgaa caagtactgg aactcctcta cagccacttc
     7561 actgtgtaac atttttaggg gaagttactt ggctggagct tctctaatct acacagtaac
     7621 aagaaacgct ggcttggtca agagacgtgg gggtggaaca ggagagaccc tgggagagaa
     7681 atggaaggcc cgcttgaacc agatgtcggc cctggagttc tactcctaca aaaagtcagg
     7741 catcaccgag gtgtgcagag aagaggcccg ccgcgccctc aaggacggtg tggcaacggg
     7801 aggccatgct gtgtcccgag gaagtgcaaa gctgagatgg ttggtggagc ggggatacct
     7861 gcagccctat ggaaaggtca ttgatcttgg atgtggcaga gggggctgga gttactacgc
     7921 cgccaccatc cgcaaagttc aagaagtgaa aggatacaca aaaggaggcc ctggtcatga
     7981 agaacccgtg ttggtgcaaa gctatgggtg gaacatagtc cgtcttaaga gtggggtgga
     8041 cgtctttcat atggcggctg agccgtgtga cacgttgctg tgtgacatag gtgagtcatc
     8101 atctagtcct gaagtggaag aagcacggac gctcagagtc ctctccatgg tgggggattg
     8161 gcttgaaaaa agaccaggag ccttttgtat aaaagtgttg tgcccataca ccagcactat
     8221 gatggaaacc ctggagcgac tgcagcgtag gtatggggga ggactggtca gagtgccact
     8281 ctcccgcaac tctacacatg agatgtactg ggtctctgga gcgaaaagca acaccataaa
     8341 aagtgtgtcc accacgagcc agctcctctt ggggcgcatg gacgggccta ggaggccagt
     8401 gaaatatgag gaggatgtga atctcggctc tggcacgcgg gctgtggtaa gctgcgctga
     8461 agctcccaac atgaagatca ttggtaaccg cattgaaagg atccgcagtg agcacgcgga
     8521 aacgtggttc tttgacgaga accacccata taggacatgg gcttaccatg gaagctatga
     8581 ggcccccaca caagggtcag cgtcctctct aataaacggg gttgtcaggc tcctgtcaaa
     8641 accctgggat gtggtgactg gagtcacagg aatagccatg accgacacca caccgtatgg
     8701 tcagcaaaga gttttcaagg aaaaagtgga cactagggtg ccagaccccc aagaaggcac
     8761 tcgtcaggtt atgagcatgg tctcttcctg gttgtggaaa gagctaggca aacacaaacg
     8821 gccacgagtc tgtaccaaag aagagttcat caacaaggtt cgtagcaatg cagcattagg
     8881 ggcaatattt gaagaggaaa aagagtggaa gactgcagtg gaagctgtga acgatccaag
     8941 gttctgggct ctagtggaca aggaaagaga gcaccacctg agaggagagt gccagagttg
     9001 tgtgtacaac atgatgggaa aaagagaaaa gaaacaaggg gaatttggaa aggccaaggg
     9061 cagccgcgcc atctggtata tgtggctagg ggctagattt ctagagttcg aagcccttgg
     9121 attcttgaac gaggatcact ggatggggag agagaactca ggaggtggtg ttgaagggct
     9181 gggattacaa agactcggat atgtcctaga agagatgagt cgcataccag gaggaaggat
     9241 gtatgcagat gacactgctg gctgggacac ccgcattagc aggtttgatc tggagaatga
     9301 agctctaatc accaaccaaa tggagaaagg gcacagggcc ttggcattgg ccataatcaa
     9361 gtacacatac caaaataaag tggtaaaggt ccttagacca gctgaaaaag ggaaaacagt
     9421 tatggacatt atttcgagac aagaccaaag ggggagcgga caagttgtca cttacgctct
     9481 taacacattt accaacctag tggtgcaact cattcggaat atggaggctg aggaagttct
     9541 agagatgcaa gacttgtggc tgctgcggag gtcagagaaa gtgaccaact ggttgcagag
     9601 caacggatgg gataggctca aacgaatggc agtcagtgga gatgattgcg ttgtgaagcc
     9661 aattgatgat aggtttgcac atgccctcag gttcttgaat gatatgggaa aagttaggaa
     9721 ggacacacaa gagtggaaac cctcaactgg atgggacaac tgggaagaag ttccgttttg
     9781 ctcccaccac ttcaacaagc tccatctcaa ggacgggagg tccattgtgg ttccctgccg
     9841 ccaccaagat gaactgattg gccgggcccg cgtctctcca ggggcgggat ggagcatccg
     9901 ggagactgct tgcctagcaa aatcatatgc gcaaatgtgg cagctccttt atttccacag
     9961 aagggacctc cgactgatgg ccaatgccat ttgttcatct gtgccagttg actgggttcc
    10021 aactgggaga actacctggt caatccatgg aaagggagaa tggatgacca ctgaagacat
    10081 gcttgtggtg tggaacagag tgtggattga ggagaacgac cacatggaag acaagacccc
    10141 agttgcgaaa tggacagaca ttccctattt gggaaaaagg gaagacttgt ggtgtggatc
    10201 tctcataggg cacagaccgc gcaccacctg ggctgagaac attaaaaaca cagtcaacat
    10261 ggtgcgcagg atcataggtg atgaagaaaa gtacatggac tacctatcca cccaagttcg
    10321 ctacttgggt gaagaagggt ctacacctgg agtgctgtaa gcaccaatct taatgttgtc
    10381 aggcctgcta gtcagccaca gcttggggaa agctgtgcag cctgtgaccc ccccaggaga
    10441 agctgggaaa ccaagcctat agtcaggccg agaacgccat ggcacggaag aagccatgct
    10501 gcctgtgagc ccctcagagg acactgagtc aaaaaacccc acgcgcttgg aggcgcagga
    10561 tgggaaaaga aggtggcgac cttccccacc cttcaatctg gggcctgaac tggagatcag
    10621 ctgtggatct ccagaagagg gactagtggt tagaggag
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Sequences producing significant alignments:

Select:AllNone Selected:0

Sequences producing significant alignments:
Select for downloading or viewing reports Description Max score Total score Query cover E value Ident Accession
18525 18525 100% 0.0 100% KY014303.1
18474 18474 100% 0.0 99% KX198135.1
18465 18465 100% 0.0 99% KX156776.1
18462 18462 100% 0.0 99% KX156774.1
18462 18462 100% 0.0 99% KU647676.1
18456 18456 100% 0.0 99% KU820897.5
18456 18456 100% 0.0 99% KX247646.1
18456 18456 100% 0.0 99% KX156775.1
18456 18456 100% 0.0 99% KX087102.1
18444 18444 100% 0.0 99% KU922960.1
18438 18438 100% 0.0 99% KU922923.1
18433 18433 100% 0.0 99% KX893855.1
18429 18429 100% 0.0 99% KX702400.1
18429 18429 100% 0.0 99% KX548902.1
18411 18411 100% 0.0 99% KX447510.1
18408 18408 100% 0.0 99% KU991811.1
18402 18402 100% 0.0 99% KX447512.1
18402 18402 100% 0.0 99% KX369547.1
18402 18402 100% 0.0 99% KU509998.3
18399 18399 100% 0.0 99% KJ776791.2
18399 18399 100% 0.0 99% KX447509.1
18393 18393 100% 0.0 99% KX447513.1
18390 18390 100% 0.0 99% KX197205.1
18390 18390 100% 0.0 99% KX447515.1
18390 18390 100% 0.0 99% KX447511.1
18390 18390 100% 0.0 99% KX280026.1
18390 18390 100% 0.0 99% KU321639.1
18384 18384 100% 0.0 99% KX447514.1
18384 18384 100% 0.0 99% KX051563.1
18381 18381 100% 0.0 99% KX447516.1
18381 18381 100% 0.0 99% KU729218.1
18381 18381 100% 0.0 99% KU707826.1
18381 18381 100% 0.0 99% KU365779.1
18375 18375 100% 0.0 99% KX262887.1
18375 18375 100% 0.0 99% KX197192.1
18372 18372 100% 0.0 99% KX811222.1
18372 18372 99% 0.0 99% KU497555.1
18366 18366 100% 0.0 99% KY014297.1
18366 18366 100% 0.0 99% KX879604.1
18366 18366 100% 0.0 99% KX694534.1
18366 18366 100% 0.0 99% KU758877.1
18366 18366 100% 0.0 99% KU926309.1
18366 18366 100% 0.0 99% KU365780.1
18363 18363 100% 0.0 99% KU940228.1
18363 18363 100% 0.0 99% KU365777.1
18357 18357 100% 0.0 99% KX879603.1
18357 18357 100% 0.0 99% KU501217.1
18357 18357 100% 0.0 99% KU365778.1
18357 18357 100% 0.0 99% KU312312.1
18354 18354 100% 0.0 99% KY014304.1
18354 18354 100% 0.0 99% KU729217.2
18354 18354 100% 0.0 99% KU527068.1
18354 18354 100% 0.0 99% KU501216.1
18350 18350 100% 0.0 99% KY014327.1
18348 18348 100% 0.0 99% KX447517.1
18348 18348 100% 0.0 99% KX247632.1
18348 18348 100% 0.0 99% KU937936.1
18348 18348 100% 0.0 99% KU501215.1
18345 18345 100% 0.0 99% KY014315.1
18345 18345 100% 0.0 99% KX601168.1
18345 18345 100% 0.0 99% KX520666.1
18345 18345 100% 0.0 99% KX087101.2
18339 18339 100% 0.0 99% KY014296.1
18339 18339 100% 0.0 99% KX806557.2
18339 18339 100% 0.0 99% KX856011.1
18339 18339 100% 0.0 99% KX446951.1
18339 18339 100% 0.0 99% KX377337.1
18339 18339 100% 0.0 99% KU926310.1
18339 18339 100% 0.0 99% KU820898.1
18336 18336 100% 0.0 99% KX446950.1
18336 18336 100% 0.0 99% KU870645.1
18330 18330 100% 0.0 99% KU853013.1
18330 18330 100% 0.0 99% KU853012.1
18327 18327 100% 0.0 99% KY014300.1
18327 18327 100% 0.0 99% LC190723.1
18327 18327 100% 0.0 99% KX056898.1
18327 18327 100% 0.0 99% KU955590.1
18323 18323 100% 0.0 99% KX766028.1
18321 18321 100% 0.0 99% KY014321.1
18321 18321 100% 0.0 99% KU740184.2
18321 18321 100% 0.0 99% KU761564.1
18318 18318 100% 0.0 99% KY014295.1
18318 18318 100% 0.0 99% KX842449.2
18312 18312 100% 0.0 99% KX766029.1
18309 18309 100% 0.0 99% KX922707.1
18309 18309 100% 0.0 99% KX673530.1
18309 18309 100% 0.0 99% KX117076.1
18305 18305 100% 0.0 99% KY014320.1
18305 18305 100% 0.0 99% KX922706.1
18303 18303 100% 0.0 99% KY014323.1
18303 18303 100% 0.0 99% KY014322.1
18303 18303 100% 0.0 99% KY014314.1
18303 18303 100% 0.0 99% KX922703.1
18303 18303 100% 0.0 99% KX838906.2
18303 18303 100% 0.0 99% KX838905.2
18303 18303 100% 0.0 99% KX832731.1
18300 18300 100% 0.0 99% KY014316.1
18300 18300 100% 0.0 99% KX922704.1
18300 18300 100% 0.0 99% KX185891.1
18300 18300 100% 0.0 99% KU963796.1
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LOCUS       KY014304               10659 bp    RNA     linear   VRL 21-OCT-2016
DEFINITION  Zika virus isolate Zika virus/H.sapiens-wt/DOM/2016/BB-0180-SER
            polyprotein gene, complete cds.
ACCESSION   KY014304
VERSION     KY014304.1
DBLINK      BioProject: PRJNA344504
            BioSample: SAMN05844989
KEYWORDS    .
SOURCE      Zika virus
  ORGANISM  Zika virus
            Viruses; ssRNA viruses; ssRNA positive-strand viruses, no DNA
            stage; Flaviviridae; Flavivirus.
REFERENCE   1  (bases 1 to 10659)
  AUTHORS   Baniecki,M.L., Barnes,K.G., Bosch,I., Freije,C.A., Gehrke,L.,
            Gladden-Young,A.D., Gnirke,A., Luo,C.Y., MacInnis,B.,
            Matranga,C.B., Metsky,H.C., Park,D.J., Qu,J., Sabeti,P.C.,
            Tomkins-Tinch,C.H., West,K.L., Winnicki,S., Wohl,S. and
            Yozwiak,N.L.
  TITLE     Direct Submission
  JOURNAL   Submitted (20-OCT-2016) Viral Genomics, Infectious Disease Program
            (Infectious Disease Initiative), Broad Institute, 75 Ames St,
            Cambridge, MA 02142, USA
COMMENT     ##Assembly-Data-START##
            Assembly Method       :: github.com/broadinstitute/viral-ngs v.
                                     v1.12.0-51-g8588fdb
            Assembly Name         :: DOM_2016_BB-0180_SER-1
            Coverage              :: 250x
            Sequencing Technology :: Illumina; Swift LC
            ##Assembly-Data-END##
FEATURES             Location/Qualifiers
     source          1..10659
                     /organism="Zika virus"
                     /mol_type="genomic RNA"
                     /isolate="Zika virus/H.sapiens-wt/DOM/2016/BB-0180-SER"
                     /isolation_source="serum"
                     /host="Homo sapiens"
                     /db_xref="taxon:64320"
                     /country="Dominican Republic: Santo Domingo"
                     /collection_date="18-Apr-2016"
                     /collected_by="Hospital General de la Plaza de la Salud,
                     Santo Domingo, Dominican Republic"
     5'UTR           <1..88
     CDS             89..10360
                     /note="contains structural and nonstructural proteins"
                     /codon_start=1
                     /product="polyprotein"
                     /protein_id="AOY08525.1"
                     /translation="MKNPKKKSGGFRIVNMLKRGVARVSPFGGLKRLPAGLLLGHGPI
                     RMVLAILAFLRFTAIKPSLGLINRWGSVGKKEAMEIIKKFKKDLAAMLRIINARKEKK
                     RRGADTSVGIVGLLLTTAMAAEVTRRGSAYYMYLDRNDAGEAISFPTTLGMNKCYIQI
                     MDLGHMCDATMSYECPMLDEGVEPDDVDCWCNTTSTWVVYGTCHHKKGEARRSRRAVT
                     LPSHSTRKLQTRSQTWLESREYTKHLIRVENWIFRNPGFALAAAAIAWLLGSSTSQKV
                     IYLVMILLIAPAYSIRCIGVSNRDFVEGMSGGTWVDVVLEHGGCVTVMAQDKPTVDIE
                     LVTTTVSNMAEVRSYCYEASISDMASDSRCPTQGEAYLDKQSDTQYVCKRTLVDRGWG
                     NGCGLFGKGSLVTCAKFACSKKMTGKSIQPENLEYRIMLSVHGSQHSGMIVNDTGHET
                     DENRAKVEITPNSPRAEATLGGFGSLGLDCEPRTGLDFSDLYYLTMNNKHWLVHKEWF
                     HDIPLPWHAGADTGTPHWNNKEALVEFKDAHAKRQTVVVLGSQEGAVHTALAGALEAE
                     MDGAKGRLSSGHLKCRLKMDKLRLKGVSYSLCTAAFTFTKIPAETLHGTVTVEVQYAG
                     TDGPCKVPAQMAVDMQTLTPVGRLITANPVITESTENSKMMLELDPPFGDSYIVIGVG
                     EKKITHHWHRSGSTIGKAFEATVRGAKRMAVLGDTAWDFGSVGGALNSLGKGIHQIFG
                     AAFKSLFGGMSWFSQILIGTLLMWLGLNTKNGSISLMCLALGGVLIFLSTAVSADVGC
                     SVDFSKKETRCGTGVFVYNDVEAWRDRYKYHPDSPRRLAAAVKQAWEDGICGISSVSR
                     MENIMWRSVEGELNAILEENGVQLTVVVGSVKNPMWRGPQRLPVPVNELPHGWKAWGK
                     SYFVRAAKTNNSFVVDGDTLKECPLKHRAWNSFLVEDHGFGVFHTSVWLKVREDYSLE
                     CDPAVIGTAVKGKEAVHSDLGYWIESEKNDTWRLKRAHLIEMKTCEWPKSHTLWTDGI
                     EESDLIIPKSLAGPLSHHNTREGYRTQMKGPWHSEELEIRFEECPGTKVHVEETCGTR
                     GPSLRSTTASGRVIEEWCCRECTMPPLSFRAKDGCWYGMEIRPRKEPESNLVRSVVTA
                     GSTDHMDHFSLGVLVILLMVQEGLKKRMTTKIIISTSMAVLVAMILGGFSMSDLAKLA
                     ILMGATFAEMNTGGDVAHLALIAAFKVRPALLVSFIFRANWTPRESMLLALASCLLQT
                     AISALEGDLMVLINGFALAWLAIRAMVVPRTDNITLAILAALTPLARGTLLVAWRAGL
                     ATCGGFMLLSLKGKGSVKKNLPFVMALGLTAVRLVDPINVVGLLLLTRSGKRSWPPSE
                     VLTAVGLICALAGGFAKADIEMAGPMAAVGLLIVSYVVSGKSVDMYIERAGDITWEKD
                     AEVTGNSPRLDVALDESGDFSLVEDDGPPMREIILKVVLMTICGMNPIAIPFAAGAWY
                     VYVKTGKRSGALWDVPAPKEVKKGETTDGVYRVMTRRLLGSTQVGVGVMQEGVFHTMW
                     HVTKGSALRSGEGRLDPYWGDVKQDLVSYCGPWKLDAAWDGHSEVQLLAVPPGERARN
                     IQTLPGIFKTKDGDIGAVALDYPAGTSGSPILDKCGRVIGLYGNGVVIKNGSYVSAIT
                     QGRREEETPVECFEPSMLKKKQLTVLDLHPGAGKTRRVLPEIVREAIKTRLRTVILAP
                     TRVVAAEMEEALRGLPVRYMTTAVNVTHSGTEIVDLMCHATFTSRLLQPIRVPNYNLY
                     IMDEAHFTDPSSIAARGYISTRVEMGEAAAIFMTATPPGTRDAFPDSNSPIMDTEVEV
                     PERAWSSGFDWVTDHSGKTVWFVPSVRNGNEIAACLTKAGKRVIQLSRKTFETEFQKT
                     KHQEWDFVVTTDISEMGANFKADRVIDSRRCLKPVILDGERVILAGPMPVTHASAAQR
                     RGRIGRNPNKPGDEYLYGGGCAETDEDHAHWLEARMLLDNIYLQDGLIASLYRPEADK
                     VAAIEGEFKLRTEQRKTFVELMKRGDLPVWLAYQVASAGITYTDRRWCFDGTTNNTIM
                     EDSVPAEVWTRHGEKRVLKPRWMDARVCSDHAALKSFKEFAAGKRGAAFGVMEALGTL
                     PGHMTERFQEAIDNLAVLMRAETGSRPYKAAAAQLPETLETIMLLGLLGTVSLGIFFV
                     LMRNKGIGKMGFGMVTLGASAWLMWLSEIEPARIACVLIVVFLLLVVLIPEPEKQRSP
                     QDNQMAIIIMVAVGLLGLITANELGWLERTKSDLSHLMGRREEGATIGFSMDIDLRPA
                     SAWAIYAALTTFITPAVQHAVTTSYNNYSLMAMATQAGVLFGMGKGMPFYAWDFGVPL
                     LMIGCYSQLTPLTLIVAIILLVAHYMYLIPGLQAAAARAAQKRTAAGIMKNPVVDGIV
                     VTDIDTMTIDPQVEKKMGQVLLIAVAVSSAILSRTAWGWGEAGALITAATSTLWEGSP
                     NKYWNSSTATSLCNIFRGSYLAGASLIYTVTRNAGLVKRRGGGTGETLGEKWKARLNQ
                     MSALEFYSYKKSGITEVCREEARRALKDGVATGGHAVSRGSAKLRWLVERGYLQPYGK
                     VIDLGCGRGGWSYYAATIRKVQEVKGYTKGGPGHEEPVLVQSYGWNIVRLKSGVDVFH
                     MAAEPCDTLLCDIGESSSSPEVEEARTLRVLSMVGDWLEKRPGAFCIKVLCPYTSTMM
                     ETLERLQRRYGGGLVRVPLSRNSTHEMYWVSGAKSNTIKSVSTTSQLLLGRMDGPRRP
                     VKYEEDVNLGSGTRAVVSCAEAPNMKIIGNRIERIRSEHAETWFVDENHPYRTWAYHG
                     SYEAPTQGSASSLVNGVVRLLSKPWDVVTGVTGIAMTDTTPYGQQRVFKEKVDTRVPD
                     PQEGTRQVMSMVSSWLWKELGKHKRPRVCTKEEFINKVRSNAALGAIFEEEKEWKTAV
                     EAVNDPRFWALVDKEREHHLRGECQSCVYNMMGKREKKQGEFGKAKGSRAIWYMWLGA
                     RFLEFEALGFLNEDHWMGRENSGGGVEGLGLQRLGYVLEEMSRIPGGRMYADDTAGWD
                     TRISRFDLENEALITNQMEKGHRALALAIIKYTYQNKVVKVLRPAEKGKTVMDIISRQ
                     DQRGSGQVVTYALNTFTNLVVQLIRNMEAEEVLEMQDLWLLRRSEKVTNWLQSNGWDR
                     LKRMAVSGDDCVVKPIDDRFAHALRFLNDMGKVRKDTQEWKPSTGWDNWEEVPFCSHH
                     FNKLHLKDGRSIVVPCRHQDELIGRARVSPGAGWSIRETACLAKSYAQMWQLLYFHRR
                     DLRLMANAICSSVPVDWVPTGRTTWSIHGKGEWMTTEDMLVVWNRVWIEENDHMEDKT
                     PVTKWTDIPYLGKREDLWCGSLIGHRPRTTWAENIKNTVNMVRRIIGEEEKYMDYLST
                     QVRYLGEEGSTPGVL"
     3'UTR           10361..10659
ORIGIN      
        1 tcagactgcg acagttcgag tttgaagcga aagctagcaa cagtatcaac aggttttatt
       61 ttggatttgg aaacgagagt ttctggtcat gaaaaaccca aaaaagaaat ccggaggatt
      121 ccggattgtc aatatgctaa aacgcggagt agcccgtgtg agcccctttg ggggcttgaa
      181 gaggctgcca gccggacttc tgctgggtca tgggcccatc aggatggtct tggcgattct
      241 agcctttttg agattcacgg caatcaagcc atcactgggt ctcatcaata gatggggttc
      301 agtggggaaa aaagaggcta tggaaataat aaagaagttc aagaaagatc tggctgccat
      361 gctgagaata atcaatgcta ggaaggagaa gaagagacga ggcgcagata ctagtgtcgg
      421 aattgttggc ctcctgctga ccacagctat ggcagcggag gtcactagac gtgggagtgc
      481 atactacatg tacttggaca gaaacgatgc tggggaggcc atatcttttc caaccacatt
      541 ggggatgaat aagtgttata tacagatcat ggatcttgga cacatgtgtg atgccaccat
      601 gagctatgaa tgccctatgc tggatgaggg ggtggaacca gatgacgtcg attgttggtg
      661 caacacgacg tcaacttggg ttgtgtacgg aacctgccat cacaaaaaag gtgaagcacg
      721 gagatctaga agagctgtga cgctcccctc ccattccact aggaagctgc aaacgcggtc
      781 gcaaacctgg ttggaatcaa gagaatacac aaagcacttg attagagtcg aaaattggat
      841 attcaggaac cctggcttcg cgttagcagc agctgccatc gcttggcttt tgggaagctc
      901 aacgagccaa aaagtcatat acttggtcat gatactgctg attgccccgg catacagcat
      961 caggtgcata ggagtcagca atagggactt tgtggaaggt atgtcaggtg ggacttgggt
     1021 tgatgttgtc ttggaacatg gaggttgtgt caccgtaatg gcacaggaca aaccgactgt
     1081 cgacatagag ctggttacaa caacagtcag caacatggcg gaggtaagat cctactgcta
     1141 tgaggcatca atatcagaca tggcttcgga cagccgctgc ccaacacaag gtgaagccta
     1201 ccttgacaag caatcagaca ctcaatatgt ctgcaaaaga acgttagtgg acagaggctg
     1261 gggaaatgga tgtggacttt ttggcaaagg gagcctggtg acatgcgcta agtttgcatg
     1321 ctccaagaaa atgaccggga agagcatcca gccagagaat ctggagtacc ggataatgct
     1381 gtcagttcat ggctcccagc acagtgggat gatcgttaat gacacaggac atgaaactga
     1441 tgagaataga gcgaaggttg agataacgcc caattcacca agagccgaag ccaccctggg
     1501 gggttttgga agcctaggac ttgattgtga accgaggaca ggccttgact tttcagattt
     1561 gtattacttg actatgaata acaagcactg gttggttcac aaggagtggt tccacgacat
     1621 tccattacct tggcacgctg gggcagacac cggaactcca cactggaaca acaaagaagc
     1681 actggtagag ttcaaggacg cacatgccaa aaggcaaact gtcgtggttc tagggagtca
     1741 agaaggagca gttcacacgg cccttgctgg agctctggag gctgagatgg atggtgcaaa
     1801 gggaaggctg tcctctggcc acttgaaatg tcgcctgaaa atggataaac ttagattgaa
     1861 gggcgtgtca tactccttgt gtaccgcagc gttcacattc accaagatcc cggctgaaac
     1921 actgcacggg acagtcacag tggaggtaca gtacgcaggg acagatggac cttgcaaggt
     1981 tccagctcag atggcggtgg acatgcaaac tctgacccca gttgggaggt tgataaccgc
     2041 caaccccgta atcactgaaa gcactgagaa ctctaagatg atgctggaac ttgatccacc
     2101 atttggggac tcttacattg tcataggagt cggggagaag aagatcaccc accactggca
     2161 caggagtggc agcaccattg gaaaagcatt tgaagccact gtgagaggtg ccaagagaat
     2221 ggcagtcttg ggagacacag cctgggactt tggatcagtt ggaggcgctc tcaactcatt
     2281 gggcaagggc atccatcaaa tttttggagc agctttcaaa tcattgtttg gaggaatgtc
     2341 ctggttctca caaatcctca ttggaacgtt gctgatgtgg ttgggtctga acacaaagaa
     2401 tggatctatt tccctcatgt gcttggcctt agggggagtg ttgatcttct tatccacagc
     2461 cgtctctgct gatgtggggt gctcggtgga cttctcaaag aaggagacga gatgcggtac
     2521 aggggtgttc gtctataacg acgttgaagc ctggagggac aggtacaagt accatcctga
     2581 ctccccccgt agattggcag cagcagtcaa gcaagcctgg gaagatggta tctgcgggat
     2641 ctcctctgtt tcaagaatgg aaaacatcat gtggagatca gtagaagggg agctcaatgc
     2701 aatcctggaa gagaatggag ttcaactgac ggtcgttgtg ggatctgtaa aaaaccccat
     2761 gtggagaggt ccacagagat tgcccgtgcc tgtgaacgag ctgccccacg gctggaaggc
     2821 ttgggggaaa tcgtacttcg ttagagcagc aaagacaaat aacagctttg tcgtggatgg
     2881 tgacacactg aaggaatgcc cactcaaaca tagagcatgg aacagctttc ttgtggagga
     2941 tcatgggttc ggggtatttc acactagtgt ctggctcaag gttagagaag attattcatt
     3001 agagtgtgat ccagccgtta ttggaacagc tgttaaggga aaggaggctg tacacagtga
     3061 tctaggctac tggattgaga gtgagaagaa tgacacatgg aggctgaaga gggcccatct
     3121 gatcgagatg aaaacatgtg aatggccaaa gtcccacaca ttgtggacag atggaataga
     3181 agagagtgat ctgatcatac ccaagtcttt agctgggcca ctcagccatc acaataccag
     3241 agagggctac aggacccaaa tgaaagggcc atggcacagt gaagagcttg aaattcggtt
     3301 tgaggaatgc ccaggcacta aggtccacgt ggaggaaaca tgtggaacaa gaggaccatc
     3361 tctgagatca accactgcaa gcggaagggt gatcgaggaa tggtgctgca gggagtgcac
     3421 aatgccccca ctgtcgttcc gggctaaaga tggctgttgg tatggaatgg agataaggcc
     3481 caggaaagaa ccagaaagca acttggtaag gtcagtggtg actgcaggat caactgatca
     3541 catggatcac ttctcccttg gagtgcttgt gattctgctc atggtgcagg aagggctgaa
     3601 gaagagaatg accacaaaga tcatcataag cacatcaatg gcagtgctgg tagctatgat
     3661 cctgggagga ttttcaatga gtgacctggc taagcttgca attttgatgg gtgccacctt
     3721 cgcggaaatg aacactggag gagatgtagc tcatctggcg ctgatagcgg cattcaaagt
     3781 cagaccagcg ttgctggtat ctttcatctt cagagctaat tggacacccc gtgaaagcat
     3841 gctgctggcc ttggcctcgt gtcttctgca aactgcgatc tccgccttgg aaggcgacct
     3901 gatggttctc atcaatggtt ttgctttggc ctggttggca atacgagcga tggttgttcc
     3961 acgcactgat aacatcacct tggcaatcct ggctgctctg acaccactgg cccggggcac
     4021 actgcttgtg gcgtggagag caggccttgc tacttgcggg gggtttatgc tcctctctct
     4081 gaagggaaaa ggcagtgtga agaagaactt accatttgtc atggccctgg gactaaccgc
     4141 tgtgaggctg gtcgacccca tcaacgtggt gggactgctg ttgctcacaa ggagtgggaa
     4201 gcggagctgg ccccctagcg aagtactcac agctgttggc ctgatatgcg cattggctgg
     4261 agggttcgcc aaggcagata tagagatggc tgggcccatg gccgcggtcg gtctgctaat
     4321 tgtcagttac gtggtctcag gaaagagtgt ggacatgtac attgaaagag caggtgacat
     4381 cacatgggaa aaagatgcgg aagtcactgg aaacagtccc cggctcgatg tggcgctaga
     4441 tgagagtggt gatttctccc tggtggagga tgacggtccc cccatgagag agatcatact
     4501 caaggtggtc ctgatgacca tctgtggcat gaacccaata gccataccct ttgcagctgg
     4561 agcgtggtac gtatacgtga agactggaaa aaggagtggt gctctatggg atgtgcctgc
     4621 tcccaaggaa gtaaaaaagg gggagaccac agatggagtg tacagagtaa tgactcgtag
     4681 actgctaggt tcaacacaag ttggagtggg agttatgcaa gagggggtct ttcacactat
     4741 gtggcacgtc acaaaaggat ccgcgctgag aagcggtgaa gggagacttg atccatactg
     4801 gggagatgtc aagcaggatc tggtgtcata ctgtggtcca tggaagctag atgccgcctg
     4861 ggacgggcac agcgaggtgc agctcttggc cgtgcccccc ggagagagag cgaggaacat
     4921 ccagactctg cccggaatat ttaagacaaa ggatggggac attggagcgg ttgcgctgga
     4981 ttacccagca ggaacttcag gatctccaat cctagacaag tgtgggagag tgataggact
     5041 ttatggcaat ggggtcgtga tcaaaaatgg gagttatgtt agtgccatca cccaagggag
     5101 gagggaggaa gagactcctg ttgagtgctt cgagccttcg atgctgaaga agaagcagct
     5161 aactgtctta gacttgcatc ctggagctgg gaaaaccagg agagttcttc ctgaaatagt
     5221 ccgtgaagct ataaaaacaa gactccgtac tgtgatctta gctccaacca gggttgtcgc
     5281 tgctgaaatg gaggaagccc ttagagggct tccagtgcgt tatatgacaa cagcagtcaa
     5341 tgtcacccat tctggaacag aaatcgtcga cttaatgtgc catgccacct tcacttcacg
     5401 tctactacag ccaatcagag tccccaacta taatctgtat attatggatg aggcccactt
     5461 cacagatccc tcaagtatag cagcaagagg atacatttca acaagggttg agatgggcga
     5521 ggcggctgcc atcttcatga ccgccacgcc accaggaacc cgtgacgcat ttccggactc
     5581 caactcacca attatggaca ccgaagtgga agtcccagag agagcctgga gctcaggctt
     5641 tgattgggtg acggatcatt ctggaaaaac agtttggttt gttccaagcg tgaggaacgg
     5701 caatgagatc gcagcttgtc tgacaaaggc tggaaaacgg gtcatacagc tcagcagaaa
     5761 gacttttgag acagagttcc agaaaacaaa acatcaagag tgggactttg tcgtgacaac
     5821 cgacatttca gagatgggcg ccaactttaa agctgaccgt gtcatagatt ccaggagatg
     5881 cctaaagccg gtcatacttg atggcgagag agtcattctg gctggaccca tgcctgtcac
     5941 acatgccagc gctgcccaga ggagggggcg cataggcagg aatcccaaca aacctggaga
     6001 tgagtatctg tatggaggtg ggtgcgcaga gactgacgaa gaccatgcac actggcttga
     6061 agcaagaatg ctccttgaca atatttacct ccaagatggc ctcatagcct cgctctatcg
     6121 acctgaggcc gacaaagtag cagccattga gggagagttc aagcttagga cggagcaaag
     6181 gaagaccttt gtggaactca tgaaaagagg agatcttcct gtttggctgg cctatcaggt
     6241 tgcatctgcc ggaataacct acacagatag aagatggtgc tttgatggca cgaccaacaa
     6301 caccataatg gaagacagtg tgccggcaga ggtgtggacc agacacggag agaaaagagt
     6361 gctcaaaccg aggtggatgg acgccagagt ttgttcagat catgcggccc tgaagtcatt
     6421 caaggagttt gccgctggga aaagaggagc ggcttttgga gtgatggaag ccctgggaac
     6481 actgccagga cacatgacag agagattcca ggaagccatt gacaacctcg ctgtgctcat
     6541 gcgggcagag actggaagca ggccttacaa agccgcggcg gcccaattgc cggagaccct
     6601 agagaccatt atgcttttgg ggttgctggg aacagtctcg ctgggaatct ttttcgtctt
     6661 gatgaggaac aagggcatag ggaagatggg ctttggaatg gtgactcttg gggccagcgc
     6721 atggctcatg tggctctcgg aaattgagcc agccagaatt gcatgtgtcc tcattgttgt
     6781 gttcctattg ctggtggtgc tcatacctga gccagaaaag caaagatctc cccaggacaa
     6841 ccaaatggca atcatcatca tggtagcagt aggtcttctg ggcttgatca ccgccaatga
     6901 actcggatgg ttggagagaa caaagagtga cctaagccat ctaatgggaa ggagagagga
     6961 gggagcaacc ataggattct caatggacat tgacctgcgg ccagcctcag cttgggccat
     7021 ctatgctgcc ttgacaactt tcattacccc agccgtccaa catgcagtga ccacttcata
     7081 caacaactac tccttaatgg cgatggccac gcaagctgga gtgttgtttg gtatgggcaa
     7141 agggatgcca ttctacgcat gggactttgg agtcccgctg ctaatgatag gttgctactc
     7201 acaattaaca cccctgaccc taatagtggc catcattttg ctcgtggcgc actacatgta
     7261 cttgatccca gggctgcagg cagcagctgc gcgtgctgcc cagaagagaa cggcagctgg
     7321 catcatgaag aaccctgttg tggatggaat agtggtgact gacattgaca caatgacaat
     7381 tgacccccaa gtggagaaaa agatgggaca ggtgctactc atagcagtag ccgtctccag
     7441 cgccatactg tcgcggaccg cctgggggtg gggggaggct ggggccctga tcacagccgc
     7501 aacttccact ttgtgggaag gctctccgaa caagtactgg aactcctcta cagccacttc
     7561 actgtgtaac atttttaggg gaagttactt ggctggagct tctctaatct acacagtaac
     7621 aagaaacgct ggcttggtca agagacgtgg gggtggaaca ggagagaccc tgggagagaa
     7681 atggaaggcc cgcttgaacc agatgtcggc cctggagttc tactcctaca aaaagtcagg
     7741 catcaccgag gtgtgcagag aagaggcccg ccgcgccctc aaggacggtg tggcaacggg
     7801 aggccatgct gtgtcccgag gaagtgcaaa gctgagatgg ttggtggagc ggggatacct
     7861 gcagccctat ggaaaggtca ttgatcttgg atgtggcaga gggggctgga gttactacgc
     7921 cgccaccatc cgcaaagttc aagaagtgaa aggatacaca aaaggaggcc ctggtcatga
     7981 agaacccgtg ttggtgcaaa gctatgggtg gaacatagtc cgtctcaaga gtggggtgga
     8041 cgtctttcat atggcggctg agccgtgtga cacgttgctg tgtgacatag gtgagtcatc
     8101 atctagtcct gaagtggaag aagcacggac gctcagagtc ctctccatgg tgggggattg
     8161 gcttgaaaaa agaccaggag ccttttgtat aaaagtgttg tgcccataca ccagcactat
     8221 gatggaaacc ctggagcgac tgcagcgtag gtatggggga ggactggtca gagtgccact
     8281 ctcccgcaac tctacacatg agatgtactg ggtctctgga gcgaaaagca acaccataaa
     8341 aagtgtgtcc accacgagcc agctcctctt ggggcgcatg gacgggccta ggaggccagt
     8401 gaaatatgag gaggatgtga atctcggctc tggcacgcgg gctgtggtaa gctgcgctga
     8461 agctcccaac atgaagatca ttggtaaccg cattgaaagg atccgcagtg agcacgcgga
     8521 aacgtggttc gttgacgaga accacccata taggacatgg gcttaccatg gaagctatga
     8581 ggcccccaca caagggtcag catcctctct agtaaacggg gttgtcaggc tcctgtcaaa
     8641 accctgggat gtggtgactg gagtcacagg aatagccatg accgacacca caccgtatgg
     8701 tcagcaaaga gttttcaagg aaaaagtgga cactagggtg ccagaccccc aagaaggcac
     8761 tcgtcaggtt atgagcatgg tctcttcctg gttgtggaaa gagctaggca aacacaaacg
     8821 gccacgagtc tgtaccaaag aagagttcat caacaaggtt cgtagcaatg cagcattagg
     8881 ggcaatattt gaagaggaaa aagagtggaa gactgcagtg gaagctgtga acgatccaag
     8941 gttctgggct ctagtggaca aggaaagaga gcaccacctg agaggagagt gccagagttg
     9001 tgtgtacaac atgatgggaa aaagagaaaa gaaacaaggg gaatttggaa aggccaaggg
     9061 cagccgcgcc atctggtata tgtggctagg ggctagattt ctagagttcg aagcccttgg
     9121 attcttgaac gaggatcact ggatggggag agagaactca ggaggtggtg ttgaagggct
     9181 gggattacaa agactcggat atgtcctaga agagatgagt cgcataccag gaggaaggat
     9241 gtatgcagat gacactgctg gctgggatac ccgcatcagc aggtttgatc tagagaatga
     9301 agctctaatc accaaccaaa tggagaaagg gcacagggcc ttggcattgg ccataatcaa
     9361 gtacacatac caaaataaag tggtaaaggt ccttagacca gctgaaaaag ggaaaacagt
     9421 tatggacatt atttcgagac aagaccaaag ggggagcgga caagttgtca cttacgctct
     9481 taacacattt accaacctag tggtgcaact cattcggaat atggaggctg aggaagttct
     9541 agagatgcaa gacttgtggc tgctgcggag gtcagagaaa gtgaccaact ggttgcagag
     9601 caacggatgg gataggctca aacgaatggc agtcagtgga gatgattgcg ttgtgaagcc
     9661 aattgatgat aggtttgcac atgccctcag gttcttgaat gatatgggaa aagttaggaa
     9721 ggacacacaa gagtggaaac cctcaactgg atgggacaac tgggaagaag ttccgttttg
     9781 ctcccaccac ttcaacaagc tccatctcaa ggacgggagg tccattgtgg ttccctgccg
     9841 ccaccaagat gaactgattg gccgggcccg cgtctctcca ggggcgggat ggagcatccg
     9901 ggagactgct tgcctagcaa aatcatatgc gcaaatgtgg cagctccttt atttccacag
     9961 aagggacctc cgactgatgg ccaatgccat ttgttcatct gtgccagttg actgggttcc
    10021 aactgggaga actacctggt caatccatgg aaagggagaa tggatgacca ctgaagacat
    10081 gcttgtggtg tggaacagag tgtggattga ggagaacgac cacatggaag acaagacccc
    10141 agttacgaaa tggacagaca ttccctattt gggaaaaagg gaagacttgt ggtgtggatc
    10201 tctcataggg cacagaccgc gcaccacctg ggctgagaac attaaaaaca cagtcaacat
    10261 ggtgcgcagg atcataggtg aggaagaaaa gtacatggac tacctatcca cccaagttcg
    10321 ctacttgggt gaagaagggt ctacacctgg agtgctgtaa gcaccaatct taatgttgtc
    10381 aggcctgcta gtcagccaca gcttggggaa agctgtgcag cctgtggccc ccccaggaga
    10441 agctgggaaa ccaagcctat agtcaggccg agaacgccat ggcacggaag aagccatgct
    10501 gcctgtgagc ccctcagagg acactgagtc aaaaaacccc acgcgcttgg aggcgcagga
    10561 tgggaaaaga aggtggcgac cttccccacc cttcaatctg gggcctgaac tggagatcag
    10621 ctgtggatct ccagaagagg gactagtggt tagaggaga
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Sequences producing significant alignments:

Select:AllNone Selected:0

Sequences producing significant alignments:
Select for downloading or viewing reports Description Max score Total score Query cover E value Ident Accession
18525 18525 100% 0.0 100% KY014304.1
18474 18474 100% 0.0 99% KU853013.1
18474 18474 100% 0.0 99% KU853012.1
18471 18471 100% 0.0 99% KY014300.1
18471 18471 100% 0.0 99% LC190723.1
18465 18465 100% 0.0 99% KY014321.1
18462 18462 100% 0.0 99% KY014295.1
18462 18462 100% 0.0 99% KX842449.2
18453 18453 100% 0.0 99% KX922707.1
18447 18447 100% 0.0 99% KY014323.1
18447 18447 100% 0.0 99% KY014322.1
18447 18447 100% 0.0 99% KY014314.1
18447 18447 100% 0.0 99% KX922703.1
18447 18447 100% 0.0 99% KX838906.2
18447 18447 100% 0.0 99% KX838905.2
18447 18447 100% 0.0 99% KX832731.1
18446 18446 100% 0.0 99% KX922706.1
18444 18444 100% 0.0 99% KY014316.1
18444 18444 100% 0.0 99% KX922704.1
18444 18444 100% 0.0 99% KX673530.1
18438 18438 100% 0.0 99% KX838904.2
18437 18437 100% 0.0 99% KX922705.1
18435 18435 100% 0.0 99% KY014324.1
18429 18429 100% 0.0 99% KX922708.1
18426 18426 100% 0.0 99% KY014299.1
18393 18393 100% 0.0 99% KX447510.1
18390 18390 100% 0.0 99% KX280026.1
18384 18384 100% 0.0 99% KX447512.1
18384 18384 100% 0.0 99% KX369547.1
18384 18384 100% 0.0 99% KU509998.3
18381 18381 100% 0.0 99% KJ776791.2
18381 18381 100% 0.0 99% KX447509.1
18381 18381 100% 0.0 99% KU991811.1
18381 18381 100% 0.0 99% KU729217.2
18375 18375 100% 0.0 99% KX447513.1
18372 18372 100% 0.0 99% KX811222.1
18372 18372 100% 0.0 99% KX197205.1
18372 18372 100% 0.0 99% KX447515.1
18372 18372 100% 0.0 99% KX447511.1
18372 18372 100% 0.0 99% KU321639.1
18366 18366 100% 0.0 99% KX879604.1
18366 18366 100% 0.0 99% KX447514.1
18366 18366 100% 0.0 99% KX051563.1
18363 18363 100% 0.0 99% KX447516.1
18363 18363 100% 0.0 99% KU729218.1
18363 18363 100% 0.0 99% KU707826.1
18363 18363 100% 0.0 99% KU527068.1
18363 18363 100% 0.0 99% KU365779.1
18357 18357 100% 0.0 99% KX879603.1
18357 18357 100% 0.0 99% KX262887.1
18357 18357 100% 0.0 99% KX197192.1
18357 18357 100% 0.0 99% KU926310.1
18357 18357 100% 0.0 99% KU926309.1
18354 18354 100% 0.0 99% KY014303.1
18354 18354 100% 0.0 99% KU940228.1
18348 18348 100% 0.0 99% KX694534.1
18348 18348 100% 0.0 99% KX198135.1
18348 18348 100% 0.0 99% KU501217.1
18348 18348 100% 0.0 99% KU365780.1
18345 18345 100% 0.0 99% KU647676.1
18345 18345 100% 0.0 99% KU501216.1
18345 18345 100% 0.0 99% KU365777.1
18339 18339 100% 0.0 99% KY014297.1
18339 18339 100% 0.0 99% KX447517.1
18339 18339 100% 0.0 99% KU758877.1
18339 18339 100% 0.0 99% KX247646.1
18339 18339 100% 0.0 99% KX156776.1
18336 18336 100% 0.0 99% KX520666.1
18336 18336 100% 0.0 99% KX156774.1
18336 18336 99% 0.0 99% KU497555.1
18332 18332 100% 0.0 99% KY014327.1
18330 18330 100% 0.0 99% KU820897.5
18330 18330 100% 0.0 99% KX247632.1
18330 18330 100% 0.0 99% KX156775.1
18330 18330 100% 0.0 99% KX087102.1
18330 18330 100% 0.0 99% KU365778.1
18330 18330 100% 0.0 99% KU312312.1
18327 18327 100% 0.0 99% KY014315.1
18327 18327 100% 0.0 99% KU922960.1
18321 18321 100% 0.0 99% KY014296.1
18321 18321 100% 0.0 99% KX806557.2
18321 18321 100% 0.0 99% KX856011.1
18321 18321 100% 0.0 99% KX548902.1
18321 18321 100% 0.0 99% KX446951.1
18321 18321 100% 0.0 99% KU937936.1
18321 18321 100% 0.0 99% KU922923.1
18321 18321 100% 0.0 99% KU501215.1
18318 18318 100% 0.0 99% KX601168.1
18318 18318 100% 0.0 99% KX446950.1
18318 18318 100% 0.0 99% KX087101.2
18318 18318 100% 0.0 99% KU870645.1
18316 18316 100% 0.0 99% KX893855.1
18312 18312 100% 0.0 99% KX702400.1
18312 18312 100% 0.0 99% KX377337.1
18303 18303 100% 0.0 99% KX766029.1
18303 18303 100% 0.0 99% KU820898.1
18300 18300 100% 0.0 99% KX056898.1
18300 18300 100% 0.0 99% KU955590.1
18296 18296 100% 0.0 99% KX766028.1
18294 18294 100% 0.0 99% KU740184.2
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LOCUS       KY014321               10643 bp    RNA     linear   VRL 21-OCT-2016
DEFINITION  Zika virus isolate Zika virus/H.sapiens-wt/DOM/2016/BB-0115-SER
            polyprotein gene, complete cds.
ACCESSION   KY014321
VERSION     KY014321.1
DBLINK      BioProject: PRJNA344504
            BioSample: SAMN05844988
KEYWORDS    .
SOURCE      Zika virus
  ORGANISM  Zika virus
            Viruses; ssRNA viruses; ssRNA positive-strand viruses, no DNA
            stage; Flaviviridae; Flavivirus.
REFERENCE   1  (bases 1 to 10643)
  AUTHORS   Baniecki,M.L., Barnes,K.G., Bosch,I., Freije,C.A., Gehrke,L.,
            Gladden-Young,A.D., Gnirke,A., Luo,C.Y., MacInnis,B.,
            Matranga,C.B., Metsky,H.C., Park,D.J., Qu,J., Sabeti,P.C.,
            Tomkins-Tinch,C.H., West,K.L., Winnicki,S., Wohl,S. and
            Yozwiak,N.L.
  TITLE     Direct Submission
  JOURNAL   Submitted (20-OCT-2016) Viral Genomics, Infectious Disease Program
            (Infectious Disease Initiative), Broad Institute, 75 Ames St,
            Cambridge, MA 02142, USA
COMMENT     ##Assembly-Data-START##
            Assembly Method       :: github.com/broadinstitute/viral-ngs v.
                                     v1.12.0-51-g8588fdb
            Assembly Name         :: DOM_2016_BB-0115_SER-1
            Coverage              :: 58x
            Sequencing Technology :: Illumina; Swift LC
            ##Assembly-Data-END##
FEATURES             Location/Qualifiers
     source          1..10643
                     /organism="Zika virus"
                     /mol_type="genomic RNA"
                     /isolate="Zika virus/H.sapiens-wt/DOM/2016/BB-0115-SER"
                     /isolation_source="serum"
                     /host="Homo sapiens"
                     /db_xref="taxon:64320"
                     /country="Dominican Republic: Santo Domingo"
                     /collection_date="11-Apr-2016"
                     /collected_by="Hospital General de la Plaza de la Salud,
                     Santo Domingo, Dominican Republic"
     5'UTR           <1..88
     CDS             89..10360
                     /note="contains structural and nonstructural proteins"
                     /codon_start=1
                     /product="polyprotein"
                     /protein_id="AOY08542.1"
                     /translation="MKNPKKKSGGFRIVNMLKRGVARVSPFGGLKRLPAGLLLGHGPI
                     RMVLAILAFLRFTAIKPSLGLINRWGSVGKKEAMEIIKKFKKDLAAMLRIINARKEKK
                     RRGADTSVGIVGLLLTTAMAAEVTRRGSAYYMYLDRNDAGEAISFPTTLGMNKCYIQI
                     MDLGHMCDATMSYECPMLDEGVEPDDVDCWCNTTSTWVVYGTCHHKKGEARRSRRAVT
                     LPSHSTRKLQTRSQTWLESREYTKHLIRVENWIFRNPGFALAAAAIAWLLGSSTSQKV
                     IYLVMILLIAPAYSIRCIGVSNRDFVEGMSGGTWVDVVLEHGGCVTVMAQDKPTVDIE
                     LVTTTVSNMAEVRSYCYEASISDMASDSRCPTQGEAYLDKQSDTQYVCKRTLVDRGWG
                     NGCGLFGKGSLVTCAKFACSKKMTGKSIQPENLEYRIMLSVHGSQHSGMIVNDTGHET
                     DENRAKVEITPNSPRAEATLGGFGSLGLDCEPRTGLDFSDLYYLTMNNKHWLVHKEWF
                     HDIPLPWHAGADTGTPHWNNKEALVEFKDAHAKRQTVVVLGSQEGAVHTALAGALEAE
                     MDGAKGRLSSGHLKCRLKMDKLRLKGVSYSLCTAAFTFTKIPAETLHGTVTVEVQYAG
                     TDGPCKVPAQMAVDMQTLTPVGRLITANPVITESTENSKMMLELDPPFGDSYIVIGVG
                     EKKITHHWHRSGSTIGKAFEATVRGAKRMAVLGDTAWDFGSVGGALNSLGKGIHQIFG
                     AAFKSLFGGMSWFSQILIGTLLMWLGLNTKNGSISLMCLALGGVLIFLSTAVSADVGC
                     SVDFSKKETRCGTGVFVYNDVEAWRDRYKYHPDSPRRLAAAVKQAWEDGICGISSVSR
                     MENIMWRSVEGELNAILEENGVQLTVVVGSVKNPMWRGPQRLPVPVNELPHGWKAWGK
                     SYFVRAAKTNNSFVVDGDTLKECPLKHRAWNSFLVEDHGFGVFHTSVWLKVREDYSLE
                     CDPAVIGTAVKGKEAVHSDLGYWIESEKNDTWRLKRAHLIEMKTCEWPKSHTLWTDGI
                     EESDLIIPKSLAGPLSHHNTREGYRTQMKGPWHSEELEIRFEECPGTKVHVEETCGTR
                     GPSLRSTTASGRVIEEWCCRECTMPPLSFRAKDGCWYGMEIRPRKEPESNLVRSVVTA
                     GSTDHMDHFSLGVLVILLMVQEGLKKRMTTKIIISTSMAVLVAMILGGFSMSDLAKLA
                     ILMGATFAEMNTGGDVAHLALIAAFKVRPALLVSFIFRANWTPRESMLLALASCLLQT
                     AISALEGDLMVLINGFALAWLAIRAMVVPRTDNITLAILAALTPLARGTLLVAWRAGL
                     ATCGGFMLLSLKGKGSVKKNLPFVMALGLTAVRLVDPINVVGLLLLTRSGKRSWPPSE
                     VLTAVGLICALAGGFAKADIEMAGPMAAVGLLIVSYVVSGKSVDMYIERAGDITWEKD
                     AEVTGNSPRLDVALDESGDFSLVEDDGPPMREIILKVVLMTICGMNPIAIPFAAGAWY
                     VYVKTGKRSGALWDVPAPKEAKKGETTDGVYRVMTRRLLGSTQVGVGVMQEGVFHTMW
                     HVTKGSALRSGEGRLDPYWGDVKQDLVSYCGPWKLDAAWDGHSEVQLLAVPPGERARN
                     IQTLPGIFKTKDGDIGAVALDYPAGTSGSPILDKCGRVIGLYGNGVVIKNGSYVSAIT
                     QGRREEETPVECFEPSMLKKKQLTVLDLHPGAGKTRRVLPEIVREAIKTRLRTVILAP
                     TRVVAAEMEEALRGLPVRYMTTAVNVTHSGTEIVDLMCHATFTSRLLQPIRVPNYNLY
                     IMDEAHFTDPSSIAARGYISTRVEMGEAAAIFMTATPPGTRDAFPDSNSPIMDTEVEV
                     PERAWSSGFDWVTDHSGKTVWFVPSVRNGNEIAACLTKAGKRVIQLSRKTFETEFQKT
                     KHQEWDFVVTTDISEMGANFKADRVIDSRRCLKPVILDGERVILAGPMPVTHASAAQR
                     RGRIGRNPNKPGDEYLYGGGCAETDEDHAHWLEARMLLDNIYLQDGLIASLYRPEADK
                     VAAIEGEFKLRTEQRKTFVELMKRGDLPVWLAYQVASAGITYTDRRWCFDGTTNNTIM
                     EDSVPAEVWTRHGEKRVLKPRWMDARVCSDHAALKSFKEFAAGKRGAAFGVMEALGTL
                     PGHMTERFQEAIDNLAVLMRAETGSRPYKAAAAQLPETLETIMLLGLLGTVSLGIFFV
                     LMRNKGIGKMGFGMVTLGASAWLMWLSEIEPARIACVLIVVFLLLVVLIPEPEKQRSP
                     QDNQMAIIIMVAVGLLGLITANELGWLERTKSDLSHLMGRREEGATIGFSMDIDLRPA
                     SAWAIYAALTTFITPAVQHAVTTSYNNYSLMAMATQAGVLFGMGKGMPFYAWDFGVPL
                     LMIGCYSQLTPLTLIVAIILLVAHYMYLIPGLQAAAARAAQKRTAAGIMKNPVVDGIV
                     VTDIDTMTIDPQVEKKMGQVLLIAVAVSSAILSRTAWGWGEAGALITAATSTLWEGSP
                     NKYWNSSTATSLCNIFRGSYLAGASLIYTVTRNAGLVKRRGGGTGETLGEKWKARLNQ
                     MSALEFYSYKKSGITEVCREEARRALKDGVATGGHAVSRGSAKLRWLVERGYLQPYGK
                     VIDLGCGRGGWSYYAATIRKVQEVKGYTKGGPGHEEPVLVQSYGWNIVRLKSGVDVFH
                     MAAEPCDTLLCDIGESSSSPEVEEARTLRVLSMVGDWLEKRPGAFCIKVLCPYTSTMM
                     ETLERLQRRYGGGLVRVPLSRNSTHEMYWVSGAKSNTIKSVSTTSQLLLGRMDGPRRP
                     VKYEEDVNLGSGTRAVVSCAEAPNMKIIGNRIERIRSEHAETWFFDENHPYRTWAYHG
                     SYEAPTQGSASSLVNGVVRLLSKPWDVVTGVTGIAMTDTTPYGQQRVFKEKVDTRVPD
                     PQEGTRQVMSMVSSWLWQELGKHKRPRVCTKEEFINKVRSNAALGAIFEEEKEWKTAV
                     EAVNDPRFWALVDKEREHHLRGECQSCVYNMMGKREKKQGEFGKAKGSRAIWYMWLGA
                     RFLEFEALGFLNEDHWMGRENSGGGVEGLGLQRLGYVLEEMSRIPGGRMYADDTAGWD
                     TRISRFDLENEALITNQMEKGHRALALAIIKYTYQNKVVKVLRPAEKGKTVMDIISRQ
                     DQRGSGQVVTYALNTFTNLVVQLIRNMEAEEVLEMQDLWLLRRSEKVTNWLQSNGWDR
                     LKRMAVSGDDCVVKPIDDRFAHALRFLNDMGKVRKDTQEWKPSTGWDNWEEVPFCSHH
                     FNKLHLKDGRSIVVPCRHQDELIGRARVSPGAGWSIRETACLAKSYAQMWQLLYFHRR
                     DLRLMANAICSSVPVDWVPTGRTTWSIHGKGEWMTTEDMLVVWNRVWIEENDHMEDKT
                     PVTKWTDIPYLGKREDLWCGSLIGHRPRTTWAENIKNTVNMVRRIIGEEEKYMDYLST
                     QVRYLGEEGSTPGVL"
     3'UTR           10361..>10643
ORIGIN      
        1 tcagactgcg acagttcgag tttgaagcga aagctagcaa cagtatcaac aggttttatt
       61 ttggatttgg aaacgagagt ttctggtcat gaaaaaccca aaaaagaaat ccggaggatt
      121 ccggattgtc aatatgctaa aacgcggagt agcccgtgtg agcccctttg ggggcttgaa
      181 gaggctgcca gccggacttc tgctgggtca tgggcccatc aggatggtct tggcgattct
      241 agcctttttg agattcacgg caatcaagcc atcactgggt ctcatcaata gatggggttc
      301 agtggggaaa aaagaggcta tggaaataat aaagaagttc aagaaagatc tggctgccat
      361 gctgagaata atcaatgcta ggaaggagaa gaagagacga ggcgcagata ctagtgtcgg
      421 aattgttggc ctcctgctga ccacagctat ggcagcggag gtcactagac gtgggagtgc
      481 atactacatg tacttggaca gaaacgatgc tggggaggcc atatcttttc caaccacatt
      541 ggggatgaat aagtgttata tacagatcat ggatcttgga cacatgtgtg atgccaccat
      601 gagctatgaa tgccctatgc tggatgaggg ggtggaacca gatgacgtcg attgttggtg
      661 caacacgacg tcaacttggg ttgtgtacgg aacctgccat cacaaaaaag gtgaagcacg
      721 gagatctaga agagctgtga cgctcccctc ccattccact aggaagctgc aaacgcggtc
      781 gcaaacctgg ttggaatcaa gagaatacac aaagcacttg attagagtcg aaaattggat
      841 attcaggaac cctggcttcg cgttagcagc agctgccatc gcttggcttt tgggaagctc
      901 aacgagccaa aaagtcatat acttggtcat gatactgctg attgccccgg catacagcat
      961 caggtgcata ggagtcagca atagggactt tgtggaaggt atgtcaggtg ggacttgggt
     1021 tgatgttgtc ttggaacatg gaggttgtgt caccgtaatg gcacaggaca aaccgactgt
     1081 cgacatagag ctggttacaa caacagtcag caacatggcg gaggtaagat cctactgcta
     1141 tgaggcatca atatcagaca tggcttcgga cagccgctgc ccaacacaag gtgaagccta
     1201 ccttgacaag caatcagaca ctcaatatgt ctgcaaaaga acgttagtgg acagaggctg
     1261 gggaaatgga tgtggacttt ttggcaaagg gagcctggtg acatgcgcta agtttgcatg
     1321 ctccaagaaa atgaccggga agagcatcca gccagagaat ctggagtacc ggataatgct
     1381 gtcagttcat ggctcccagc acagtggaat gatcgttaat gacacaggac atgaaactga
     1441 tgagaataga gcgaaggttg agataacgcc caattcacca agagccgaag ccaccctggg
     1501 gggttttgga agcctaggac ttgattgtga accgaggaca ggccttgact tttcagattt
     1561 gtattacttg actatgaata acaagcactg gttggttcac aaggagtggt tccacgacat
     1621 tccattacct tggcacgctg gggcagacac cggaactcca cactggaaca acaaagaagc
     1681 actggtagag ttcaaggacg cacatgccaa aaggcaaact gtcgtggttc tagggagtca
     1741 agaaggagca gttcacacgg cccttgctgg agctctggag gctgagatgg atggtgcaaa
     1801 gggaaggctg tcctctggcc acttgaaatg tcgcctgaaa atggataaac ttagattgaa
     1861 gggcgtgtca tactccttgt gtaccgcagc gttcacattc accaagatcc cggctgaaac
     1921 actgcacggg acagtcacag tggaggtaca gtacgcaggg acagatggac cttgcaaggt
     1981 tccagctcag atggcggtgg acatgcaaac tctgacccca gttgggaggt tgataaccgc
     2041 caaccccgta atcactgaaa gcactgagaa ctctaagatg atgctggaac ttgatccacc
     2101 atttggggac tcttacattg tcataggagt cggggagaag aagatcaccc accactggca
     2161 caggagtggc agcaccattg gaaaagcatt tgaagccact gtgagaggtg ccaagagaat
     2221 ggcagtcttg ggagacacag cctgggactt tggatcagtt ggaggcgctc tcaactcatt
     2281 gggcaagggc atccatcaaa tttttggagc agctttcaaa tcattgtttg gaggaatgtc
     2341 ctggttctca caaatcctca ttggaacgtt gctgatgtgg ttgggtctga acacaaagaa
     2401 tggatctatt tccctcatgt gcttggcctt agggggagtg ttgatcttct tatccacagc
     2461 cgtctctgct gatgtggggt gctcggtgga cttctcaaag aaggagacga gatgcggtac
     2521 aggggtgttc gtctataacg acgttgaagc ctggagggac aggtacaagt accatcctga
     2581 ctccccccgt agattggcag cagcagtcaa gcaagcctgg gaagatggta tctgcgggat
     2641 ctcctctgtt tcaagaatgg aaaacatcat gtggagatca gtagaagggg agctcaatgc
     2701 aatcctggaa gagaatggag ttcaactgac ggtcgttgtg ggatctgtaa aaaaccccat
     2761 gtggagaggt ccacagagat tgcccgtgcc tgtgaacgag ctgccccacg gctggaaggc
     2821 ttgggggaaa tcgtacttcg ttagagcagc aaagacaaat aacagctttg tcgtggatgg
     2881 tgacacactg aaggaatgcc cactcaaaca tagagcatgg aacagctttc ttgtggagga
     2941 tcatgggttc ggggtatttc acactagtgt ctggctcaag gttagagaag attattcatt
     3001 agagtgtgat ccagccgtta ttggaacagc tgttaaggga aaggaggctg tacacagtga
     3061 tctaggctac tggattgaga gtgagaagaa tgacacatgg aggctgaaga gggcccatct
     3121 gatcgagatg aaaacatgtg aatggccaaa gtcccacaca ttgtggacag atggaataga
     3181 agagagtgat ctgatcatac ccaagtcttt agctgggcca ctcagccatc acaataccag
     3241 agagggctac aggacccaaa tgaaagggcc atggcacagt gaagagcttg aaattcggtt
     3301 tgaggaatgc ccaggcacta aggtccacgt ggaggaaaca tgtggaacaa gaggaccatc
     3361 tctgagatca accactgcaa gcggaagggt gatcgaggaa tggtgctgca gggagtgcac
     3421 aatgccccca ctgtcgttcc gggctaaaga tggctgttgg tatggaatgg agataaggcc
     3481 caggaaagaa ccagaaagca acttagtaag gtcagtggtg actgcaggat caactgatca
     3541 catggatcac ttctcccttg gagtgcttgt gattctgctc atggtgcagg aagggctgaa
     3601 gaagagaatg accacaaaga tcatcataag cacatcaatg gcagtgctgg tagctatgat
     3661 cctgggagga ttttcaatga gtgacctggc taagcttgca attttgatgg gtgccacctt
     3721 cgcggaaatg aacactggag gagatgtagc tcatctggcg ctgatagcgg cattcaaagt
     3781 cagaccagcg ttgctggtat ctttcatctt cagagctaat tggacacccc gtgaaagcat
     3841 gctgctggcc ttggcctcgt gtcttttgca aactgcgatc tccgccttgg aaggcgacct
     3901 gatggttctc atcaatggtt ttgctttggc ctggttggca atacgagcga tggttgttcc
     3961 acgcactgat aacatcaccc tggcaatcct ggctgctctg acaccactgg cccggggcac
     4021 actgcttgtg gcgtggagag caggccttgc tacttgcggg gggtttatgc tcctctctct
     4081 gaagggaaaa ggcagtgtga agaagaactt accatttgtc atggccctgg gactaaccgc
     4141 tgtgaggctg gtcgacccca tcaacgtggt gggactgctg ttgctcacaa ggagtgggaa
     4201 gcggagctgg ccccctagcg aagtactcac agctgttggc ctgatatgcg cattggctgg
     4261 agggttcgcc aaggcagata tagagatggc tgggcccatg gccgcggtcg gtctgctaat
     4321 tgtcagttac gtggtctcag gaaagagtgt ggacatgtac attgaaagag caggtgacat
     4381 cacatgggaa aaagatgcgg aagtcactgg aaacagtccc cggctcgatg tggcgctaga
     4441 tgagagtggt gatttctccc tggtggagga tgacggtccc cccatgagag agatcatact
     4501 caaggtggtc ctgatgacca tctgtggcat gaacccaata gccataccct ttgcagctgg
     4561 agcgtggtac gtatacgtga agactggaaa aaggagtggt gctctatggg atgtgcctgc
     4621 tcccaaggaa gcaaaaaagg gggagaccac agatggagtg tacagagtaa tgactcgtag
     4681 actgctaggt tcaacacaag ttggagtggg agttatgcaa gaaggggtct ttcacactat
     4741 gtggcacgtc acaaaaggat ccgcgctgag aagcggtgaa gggagacttg atccatactg
     4801 gggagatgtc aagcaggatc tggtgtcata ctgtggtcca tggaagctag atgccgcctg
     4861 ggacgggcac agcgaggtgc agctcttggc cgtgcccccc ggagagagag cgaggaacat
     4921 ccagactctg cccggaatat ttaagacaaa ggatggggac attggagcgg ttgcgctgga
     4981 ttacccagca ggaacttcag gatctccaat cctagacaag tgtgggagag tgataggact
     5041 ttatggcaat ggggtcgtga tcaaaaatgg gagttatgtt agtgccatca cccaagggag
     5101 gagggaggaa gagactcctg ttgagtgctt cgagccttcg atgctgaaga agaagcagct
     5161 aactgtctta gacttgcatc ctggagctgg gaaaaccagg agagttcttc ctgaaatagt
     5221 ccgtgaagct ataaaaacaa gactccgtac tgtgatctta gctccaacca gggttgtcgc
     5281 tgctgaaatg gaggaagccc ttagagggct tccagtgcgt tatatgacaa cagcagtcaa
     5341 tgtcacccat tctggaacag aaatcgtcga cttaatgtgc catgccacct tcacttcacg
     5401 tctactacag ccaatcagag tccccaacta taatctgtat attatggatg aggcccactt
     5461 cacagatccc tcaagtatag cagcaagagg atacatttca acaagggttg agatgggcga
     5521 ggcggctgcc atcttcatga ccgccacgcc accaggaacc cgtgacgcat ttccggactc
     5581 caactcacca attatggaca ccgaagtgga agtcccagag agagcctgga gctcaggctt
     5641 tgattgggtg acggatcatt ctggaaaaac agtttggttt gttccaagcg tgaggaatgg
     5701 caatgagatc gcagcttgtc tgacaaaggc tggaaaacgg gtcatacagc tcagcagaaa
     5761 gacttttgag acagagttcc agaaaacaaa acatcaagag tgggactttg tcgtgacaac
     5821 cgacatttca gagatgggcg ccaactttaa agctgaccgt gtcatagatt ccaggagatg
     5881 cctaaagccg gtcatacttg atggcgagag agtcattctg gctggaccca tgcctgtcac
     5941 acatgccagc gctgcccaga ggagggggcg cataggcagg aatcccaaca aacctggaga
     6001 tgagtatctg tatggaggtg ggtgcgcaga gactgacgaa gaccatgcac actggcttga
     6061 agcaagaatg ctccttgaca atatttacct ccaagatggc ctcatagcct cgctctatcg
     6121 acctgaggcc gacaaagtag cagccattga gggagagttc aagcttagga cggagcaaag
     6181 gaagaccttt gtggaactca tgaaaagagg agatcttcct gtttggctgg cctatcaggt
     6241 tgcatctgcc ggaataactt acacagatag aagatggtgc tttgatggca cgaccaacaa
     6301 caccataatg gaagacagtg tgccggcaga ggtgtggacc agacacggag agaaaagagt
     6361 gctcaaaccg aggtggatgg acgccagagt ttgttcagat catgcggccc tgaagtcatt
     6421 caaggagttt gccgctggga aaagaggagc ggcttttgga gtgatggaag ccctgggaac
     6481 actgccagga cacatgacag agagattcca ggaagccatt gacaacctcg ctgtgctcat
     6541 gcgggcagag actggaagca ggccttacaa agccgcggcg gcccaattgc cggagaccct
     6601 agagaccatt atgcttttgg ggttgctggg aacagtctcg ctgggaatct ttttcgtctt
     6661 gatgaggaac aagggcatag ggaagatggg ctttggaatg gtgactcttg gggccagcgc
     6721 atggctcatg tggctctcgg aaattgagcc agccagaatt gcatgtgtcc tcattgttgt
     6781 gttcctattg ctggtggtgc tcatacctga gccagaaaag caaagatctc cccaggacaa
     6841 ccaaatggca atcatcatca tggtagcagt aggtcttctg ggcttgatca ccgccaatga
     6901 actcggatgg ttggagagaa caaagagtga cctaagccat ctaatgggaa ggagagagga
     6961 gggagcaacc ataggattct caatggacat tgacctgcgg ccagcctcag cttgggccat
     7021 ctatgctgcc ttgacaactt tcattacccc agccgtccaa catgcagtga ccacttcata
     7081 caacaactac tccttaatgg cgatggccac gcaagctgga gtgttgtttg gtatgggcaa
     7141 agggatgcca ttctacgcat gggactttgg agtcccgctg ctaatgatag gttgctactc
     7201 acaattaaca cccctgaccc taatagtggc catcattttg ctcgtggcgc actacatgta
     7261 cttgatccca gggctgcagg cagcagctgc gcgtgctgcc cagaagagaa cggcagctgg
     7321 catcatgaag aaccctgttg tggatggaat agtggtgact gacattgaca caatgacaat
     7381 tgacccccaa gtggagaaaa agatgggaca ggtgctactc atagcagtag ccgtctccag
     7441 cgccatactg tcgcggaccg cctgggggtg gggggaggct ggggccctga tcacagccgc
     7501 aacttccact ttgtgggaag gctctccgaa caagtactgg aactcctcta cagccacttc
     7561 actgtgtaac atttttaggg gaagttactt ggctggagct tctctaatct acacagtaac
     7621 aagaaacgct ggcttggtca agagacgtgg gggtggaaca ggagagaccc tgggagagaa
     7681 atggaaggcc cgcttgaacc agatgtcggc cctggagttc tactcctaca aaaagtcagg
     7741 catcaccgag gtgtgcagag aagaggcccg ccgcgccctc aaggacggtg tggcaacggg
     7801 aggccatgct gtgtcccgag gaagtgcaaa gctgagatgg ttggtggagc ggggatacct
     7861 gcagccctat ggaaaggtca ttgatcttgg atgtggcaga gggggctgga gttactacgc
     7921 cgccaccatc cgcaaagttc aagaagtgaa aggatacaca aaaggaggcc ctggtcatga
     7981 agaacccgtg ttggtgcaaa gctatgggtg gaacatagtc cgtctcaaga gtggggtgga
     8041 cgtctttcat atggcggctg agccgtgtga cacgttgctg tgtgacatag gtgagtcatc
     8101 atctagtcct gaagtggaag aagcacggac gctcagagtc ctctccatgg tgggggattg
     8161 gcttgaaaaa agaccaggag ccttttgtat aaaagtgttg tgcccataca ccagcactat
     8221 gatggaaacc ctggagcgac tgcagcgtag gtatggggga ggactggtca gagtgccact
     8281 ctcccgcaac tctacacatg agatgtactg ggtctctgga gcgaaaagca acaccataaa
     8341 aagtgtgtcc accacgagcc agctcctctt ggggcgcatg gacgggccta ggaggccagt
     8401 gaaatatgag gaggatgtga atctcggctc tggcacgcgg gctgtggtaa gctgcgctga
     8461 agctcccaac atgaagatca ttggtaaccg cattgaaagg atccgcagtg agcacgcgga
     8521 aacgtggttc tttgacgaga accacccata taggacatgg gcttaccatg gaagctatga
     8581 ggcccccaca caagggtcag catcctctct agtaaacggg gttgtcaggc tcctgtcaaa
     8641 accctgggat gtggtgactg gagtcacagg aatagccatg accgacacca caccgtatgg
     8701 tcagcaaaga gttttcaagg aaaaagtgga cactagggtg ccagaccccc aagaaggcac
     8761 tcgtcaggtt atgagcatgg tctcttcctg gttgtggcaa gagctaggca aacacaaacg
     8821 gccacgagtc tgtaccaaag aagagttcat caacaaggtt cgtagcaatg cagcattagg
     8881 ggcaatattt gaagaggaaa aagagtggaa gactgcagtg gaagctgtga acgatccaag
     8941 gttctgggct ctagtggaca aggaaagaga gcaccacctg agaggagagt gccagagttg
     9001 tgtgtacaac atgatgggaa aaagagaaaa gaaacaaggg gaatttggaa aggccaaggg
     9061 cagccgcgcc atctggtata tgtggctagg ggctagattt ctagagttcg aagcccttgg
     9121 attcttgaac gaggatcact ggatggggag agagaactca ggaggtggtg ttgaagggct
     9181 gggattacaa agactcggat atgtcctaga agagatgagt cgcataccag gaggaaggat
     9241 gtatgcagat gacactgctg gctgggatac ccgcatcagc aggtttgatc tagagaatga
     9301 agctctaatc accaaccaaa tggagaaagg gcacagggcc ttggcattgg ccataatcaa
     9361 gtacacatac caaaacaaag tggtaaaggt ccttagacca gctgaaaaag ggaaaacagt
     9421 tatggacatt atttcgagac aagaccaaag ggggagcgga caagttgtca cttacgctct
     9481 caacacattt accaacctag tggtgcaact cattcggaat atggaggctg aggaagttct
     9541 agagatgcaa gacttgtggc tgctgcggag gtcagagaaa gtgaccaact ggttgcagag
     9601 caacggatgg gataggctca aacgaatggc agtcagtgga gatgattgcg ttgtgaagcc
     9661 aattgatgat aggtttgcac atgccctcag gttcttgaat gatatgggaa aagttaggaa
     9721 ggacacacaa gagtggaaac cctcaactgg atgggacaac tgggaagaag ttccgttttg
     9781 ctcccaccac ttcaacaagc tccatctcaa ggacgggagg tccattgtgg ttccctgccg
     9841 ccaccaagat gaactgattg gccgggcccg cgtctctcca ggggcgggat ggagcatccg
     9901 ggagactgct tgcctagcaa aatcatatgc gcaaatgtgg cagctccttt atttccacag
     9961 aagggacctc cgattgatgg ccaatgccat ttgttcatct gtgccagttg actgggttcc
    10021 aactgggaga actacctggt caatccatgg aaagggagaa tggatgacca ctgaagacat
    10081 gcttgtggtg tggaacagag tgtggattga ggagaacgac cacatggaag acaagacccc
    10141 agttacgaaa tggacagaca ttccctattt gggaaaaagg gaagacttgt ggtgtggatc
    10201 tctcataggg cacagaccgc gcaccacctg ggctgagaac attaaaaaca cagtcaacat
    10261 ggtgcgcagg atcataggtg aggaagaaaa gtacatggac tacctatcca cccaagttcg
    10321 ctacttgggt gaagaagggt ctacacctgg agtgctgtaa gcaccaatct taatgttgtc
    10381 aggcctgcta gtcagccaca gcttggggaa agctgtgcag cctgtgaccc ccccaggaga
    10441 agctgggaaa ccaagcctat ggtcaggccg agaacgccat ggcacggaag aagccatgct
    10501 gcctgtgagc ccctcagagg acactgagtc aaaaaacccc acgcgcttgg aggcgcagga
    10561 tgggaaaaga aggtggcgac cttccccacc cttcaatctg gggcctgaac tggagatcag
    10621 ctgtggatct ccagaagagg gac
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