niman Posted November 11, 2016 Report Share Posted November 11, 2016 (edited) On November 4 an H5N8 warning was issued by FAO, citing a summer outbreak of H5N8 at Uvs Lake on the Mongolia / Siberian border and initial reports of H5N8 in India and Hungary (and three OI reports were published from these two countries on the same day. OIE were subsequently released for outbreaks in Poland, 2 more outbreaks in India, Germany, Austria, Switzerland, and Croatia. Sequences from the Tyva outbreak were released at GISAID (6 sequences from 5 species) and all had a poly-basic cleavage site of REKRRKR and were clade 2.3.4.4 (but distinct from the H5N8 sequences in Europe, Japan / South Korea, and North America (H5N1, H5N2, H5N8 in United States and Canada). However, the OIE report filed on 11/10/16 by Croatia notes that the poly-basic cleavage site in H5N8 in mute swans was RERRRKR signaling a lineage distinct from Tyva outbreak. Edited November 24, 2016 by niman Link to comment Share on other sites More sharing options...
niman Posted November 11, 2016 Author Report Share Posted November 11, 2016 Approximately ten swans died on the river Bidj but only two of them were available for laboratory testing. Organ samples were taken and submitted on 31 October to the Poultry centre of the Croatian Veterinary Institute. Avian influenza - subtype H5N8 was isolated. Nucleotide sequencing at the cleavage site of the hemagglutinin (HA) of the isolate revealed the multiple basic amino acid sequence "RERRRKR/GLF", which is consistent with highly pathogenic avian influenza. http://www.oie.int/wahis_2/public/wahid.php/Reviewreport/Review?page_refer=MapFullEventReport&reportid=21481 Link to comment Share on other sites More sharing options...
niman Posted November 11, 2016 Author Report Share Posted November 11, 2016 Highly pathogenic avian influenza, Croatia Information received on 10/11/2016 from Dr Tomislav Kiš, Assistant to Minister, Veterinary and Food Safety Directorate, Ministry of Agriculture, Zagreb, Croatia Summary Report type Immediate notification Date of start of the event 30/10/2016 Date of confirmation of the event 09/11/2016 Report date 10/11/2016 Date submitted to OIE 10/11/2016 Reason for notification New strain of a listed disease in the country Causal agent Highly pathogenic avian influenza virus Serotype H5N8 Nature of diagnosis Laboratory (basic), Laboratory (advanced) This event pertains to a defined zone within the country New outbreaks (1) Outbreak 1 River Bidj, Cerje, Županja, VUKOVARSKO-SRIJEMSKA Date of start of the outbreak 30/10/2016 Outbreak status Continuing (or date resolved not provided) Epidemiological unit Village Affected animals Species Susceptible Cases Deaths Destroyed Slaughtered Mute Swan:Cygnus olor(Anatidae) 10 10 0 0 Summary of outbreaks Total outbreaks: 1 Total animals affected Species Susceptible Cases Deaths Destroyed Slaughtered Mute Swan:Cygnus olor(Anatidae) 10 10 0 0 Outbreak statistics Species Apparent morbidity rate Apparent mortality rate Apparent case fatality rate Proportion susceptible animals lost* Mute Swan:Cygnus olor(Anatidae) ** ** 100.00% ** *Removed from the susceptible population through death, destruction and/or slaughter **Not calculated because of missing information Epidemiology Source of the outbreak(s) or origin of infection Unknown or inconclusive Epidemiological comments Approximately ten swans died on the river Bidj but only two of them were available for laboratory testing. Organ samples were taken and submitted on 31 October to the Poultry centre of the Croatian Veterinary Institute. Avian influenza - subtype H5N8 was isolated. Nucleotide sequencing at the cleavage site of the hemagglutinin (HA) of the isolate revealed the multiple basic amino acid sequence "RERRRKR/GLF", which is consistent with highly pathogenic avian influenza. Control measures Measures applied Vaccination prohibited No treatment of affected animals Measures to be applied No other measures Diagnostic test results Laboratory name and type Species Test Test date Result Croatian Veterinary Institute- Poultry Centre (National laboratory) Mute Swan reverse transcription - polymerase chain reaction (RT-PCR) 09/11/2016 Positive Future Reporting The event is continuing. Weekly follow-up reports will be submitted. Map of outbreak locations Link to comment Share on other sites More sharing options...
niman Posted November 11, 2016 Author Report Share Posted November 11, 2016 Link to comment Share on other sites More sharing options...
niman Posted November 11, 2016 Author Report Share Posted November 11, 2016 Map Update https://www.google.com/maps/d/edit?hl=en&hl=en&authuser=0&authuser=0&mid=1aNOepBDPUd0zdRnQE1UbSW8djsk&ll=46.39727358429026%2C11.468740940074895&z=5 Link to comment Share on other sites More sharing options...
niman Posted November 24, 2016 Author Report Share Posted November 24, 2016 On 11/11/2016 at 5:24 AM, niman said: On November 4 an H5N8 warning was issued by FAO, citing a summer outbreak of H5N8 at Uvs Lake on the Mongolia / Siberian border and initial reports of H5N8 in India and Hungary (and three OI reports were published from these two countries on the same day. OIE were subsequently released for outbreaks in Poland, 2 more outbreaks in India, Germany, Austria, Switzerland, and Croatia. Sequences from the Tyva outbreak were released at GISAID (6 sequences from 5 species) and all had a poly-basic cleavage site of REKRRKR and were clade 2.3.4.4 (but distinct from the H5N8 sequences in Europe, Japan / South Korea, and North America (H5N1, H5N2, H5N8 in United States and Canada). However, the OIE report filed on 11/10/16 by Croatia notes that the poly-basic cleavage site in H5N8 in mute swans was RERRRKR signaling a lineage distinct from Tyva outbreak. Two sets of H5N8 sequences from Mute Swans in Croatia have an REKRRKR cleavage site and are related to the Uvs Lake strain. Link to comment Share on other sites More sharing options...
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