H5N6 Confirmed At Akita Japan Zoo

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On 15th November 2016, one death case of Cygnus atratus (black swan) was found in the zoo and its sample was tested by antigen-capture kit with positive result for influenza A virus. On 17th November 2016, another death case of Cygnus atratus was found in the same facility and positive result was gained by antigen-capture kit. On 21st November 2016, the two dead cases were confirmed to be positive for H5N6 subtype influenza A virus.

http://www.oie.int/wahis_2/public/wahid.php/Reviewreport/Review?page_refer=MapFullEventReport&reportid=21608

[niman]

Highly pathogenic avian influenza, Japan

Information received on 22/11/2016 from Dr Kazuo Ito, Director, International Animal Health Affairs Office, Animal Health Division, Food Safety and Consumer Affairs Bureau, Ministry of Agriculture, Forestry and Fisheries, Tokyo, Japan

Summary

Report type	Immediate notification
Date of start of the event	15/11/2016
Date of confirmation of the event	21/11/2016
Report date	21/11/2016
Date submitted to OIE	22/11/2016
Reason for notification	Reoccurrence of a listed disease
Date of previous occurrence	17/02/2015
Manifestation of disease	Clinical disease
Causal agent	Highly pathogenic avian influenza virus
Serotype	H5N6
Nature of diagnosis	Clinical, Laboratory (basic), Laboratory (advanced)
This event pertains to	a defined zone within the country

New outbreaks (2)

Outbreak 1	Akita-shi, AKITA
Date of start of the outbreak	15/11/2016
Outbreak status	Resolved (15/11/2016)
Epidemiological unit	Zoo
Affected animals	Species Susceptible Cases Deaths Destroyed Slaughtered Black Swan:Cygnus atratus(Anatidae)   1 1 0 0

Outbreak 2	Akita-shi, AKITA
Date of start of the outbreak	17/11/2016
Outbreak status	Resolved (17/11/2016)
Epidemiological unit	Zoo
Affected animals	Species Susceptible Cases Deaths Destroyed Slaughtered Black Swan:Cygnus atratus(Anatidae)   1 1 0 0

Summary of outbreaks	Total outbreaks: 2
Total animals affected	Species Susceptible Cases Deaths Destroyed Slaughtered Black Swan:Cygnus atratus(Anatidae)   2 2 0 0
Outbreak statistics	Species Apparent morbidity rate Apparent mortality rate Apparent case fatality rate Proportion susceptible animals lost* Black Swan:Cygnus atratus(Anatidae) ** ** 100.00% **
*Removed from the susceptible population through death, destruction and/or slaughter
**Not calculated because of missing information

Epidemiology

Source of the outbreak(s) or origin of infection

Unknown or inconclusive

Epidemiological comments

On 15th November 2016, one death case of Cygnus atratus (black swan) was found in the zoo and its sample was tested by antigen-capture kit with positive result for influenza A virus. On 17th November 2016, another death case of Cygnus atratus was found in the same facility and positive result was gained by antigen-capture kit. On 21st November 2016, the two dead cases were confirmed to be positive for H5N6 subtype influenza A virus.

Control measures

Measures applied	Screening Vaccination prohibited No treatment of affected animals
Measures to be applied	No other measures

Diagnostic test results

Laboratory name and type	Species	Test	Test date	Result
Hokkaido University (OIE Reference Laboratory)	Black Swan	haemagglutination inhibition test (HIT)	19/11/2016	Positive
Hokkaido University (OIE Reference Laboratory)	Black Swan	neuraminidase inhibition assay	20/11/2016	Positive
Hokkaido University (OIE Reference Laboratory)	Black Swan	reverse transcription - polymerase chain reaction (RT-PCR)	19/11/2016	Positive
Hokkaido University (OIE Reference Laboratory)	Black Swan	reverse transcription - polymerase chain reaction (RT-PCR)	20/11/2016	Positive
Hokkaido University (OIE Reference Laboratory)	Black Swan	virus isolation	19/11/2016	Positive
Hokkaido University (OIE Reference Laboratory)	Black Swan	virus sequencing	21/11/2016	Positive

Future Reporting

The event is continuing. Weekly follow-up reports will be submitted.

Map of outbreak locations

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Map Update

https://www.google.com/maps/d/edit?hl=en&hl=en&authuser=0&authuser=0&mid=1qGSwDIT9mRts9KM-a2v5DRfRPnw&ll=39.67499263219223%2C140.07468597459103&z=12

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