niman Posted March 3, 2017 Report Posted March 3, 2017 The release of HPAI sequences (at GISAID) from birds or people linked to Guangdong, China has raised concerns. Currently four human sequences have been made public and all four have the same poly-basic cleavage site in H7 and the Tamiflu resistance marker in N9, R292K. This is in marked contrast to seven avian HPAI sequences and over 60 recent human LPAI H7N9 sequences, all of which are Tamiflu sensitive. This linkage between the resistance and human HPAI sequences was actively ignored at the recent WHO presser, even though the vast majority of the above sequences were generated by the WHO regional influenza center in Beijing, who was one of the two presenters at the presser. The presser noted that 7% of recent human sequences were Tamiflu resistant, but failed to note that 7% of the human sequences were HPAI and the frequency was the same as Tamiflu resistance because 100% of the human HPAI sequences had R282K and 0% of the LPAI H7N9 had this change (even though both populations were treated with Tamiflu). Although the presser was actively covered in subsequent media reports, the dramatic correlation between Tamiflu resistance and human HPAI was not cited, raising serious transparency concerns.
niman Posted March 3, 2017 Author Report Posted March 3, 2017 Podcast on WHO presser and comments on 7% Tamiflu resistance (R292K) http://recombinomics.co/thedrnimanshow/2017/03/030117.mp3
niman Posted March 3, 2017 Author Report Posted March 3, 2017 (edited) All of the above sequences were submitted to GISAID by the WHO influenza Center in Beijing. The first sequences (7 environmental and 2 human) have an HA size of 1695 (due to the polybasic cleavage site created by the insertion of 12 nucleotides). The next 60 sequence are human low path with an HA size of 1683. These sequences were from samples collected in late 2016 (Nov & Dec) and early 2017 (Jan). This sequences were made public prior to the WHO pressor on March 1. Edited March 3, 2017 by niman
niman Posted March 3, 2017 Author Report Posted March 3, 2017 Isolate name: A/Environment/Guangdong/C162811110/2016(H7,H9,N2,N9) Isolate ID: EPI_ISL_249316 Passage details/history: E1 Type: A Lineage: Sample information Collection date: 2016-11-07 Host Environment Additional host information: Location: China Additional location information: Guangdong Institute information Originating lab: Sample ID given by the sample provider: Address: Submitting lab: WHO Chinese National Influenza Center Sample ID given by the submitting laboratory: Authors: Address: WHO Chinese National Influenza Center Virology Institute, Chinese CDC 155 Changbai Road, Changping District, Beijing 102206 China Publication Publication In vivo antiviral resistance Phenotype Genotype Unspecified Antiviral resistance tested by experimental procedures Adamantanes: Unknown Oseltamivir: Unknown Zanamivir: Unknown Peramivir: Unknown Other: Unknown Additional information Antigenic characterization: Note: Sequence segment identifier length accession # INSDC Sequence HA A/Environment/Guangdong/C162811110/2016-HA 1695 EPI919627 NA A/Environment/Guangdong/C162811110/2016-NA 1398 EPI919626 Submitter information Submitter: Yang, Lei Submission Date: 2017-02-20 Last modifier: Yang, Lei Last modified: 2017-02-20 Address: WHO Chinese National Influenza Center Virology Institute, Chinese CDC 155 Changbai Road, Changping District, Beijing 102206 China
niman Posted March 3, 2017 Author Report Posted March 3, 2017 Isolate detail Isolate name: A/Environment/Guangdong/C16283219/2016(H7,H9,N2,N9) Isolate ID: EPI_ISL_249315 Passage details/history: E1 Type: A Lineage: Sample information Collection date: 2016-11-02 Host Environment Additional host information: Location: China Additional location information: Guangdong Institute information Originating lab: Sample ID given by the sample provider: Address: Submitting lab: WHO Chinese National Influenza Center Sample ID given by the submitting laboratory: Authors: Address: WHO Chinese National Influenza Center Virology Institute, Chinese CDC 155 Changbai Road, Changping District, Beijing 102206 China Publication Publication In vivo antiviral resistance Phenotype Genotype Unspecified Antiviral resistance tested by experimental procedures Adamantanes: Unknown Oseltamivir: Unknown Zanamivir: Unknown Peramivir: Unknown Other: Unknown Additional information Antigenic characterization: Note: Sequence segment identifier length accession # INSDC Sequence HA A/Environment/Guangdong/C16283219/2016-HA 1695 EPI919625 NA A/Environment/Guangdong/C16283219/2016-NA 1398 EPI919624 Submitter information Submitter: Yang, Lei Submission Date: 2017-02-20 Last modifier: Yang, Lei Last modified: 2017-02-20 Address: WHO Chinese National Influenza Center Virology Institute, Chinese CDC 155 Changbai Road, Changping District, Beijing 102206 China
niman Posted March 3, 2017 Author Report Posted March 3, 2017 Isolate detail Isolate name: A/Environment/Guangdong/C16283277/2016(H7,H9,N2,N9) Isolate ID: EPI_ISL_249314 Passage details/history: E1 Type: A Lineage: Sample information Collection date: 2016-12-07 Host Environment Additional host information: Location: China Additional location information: Guangdong Institute information Originating lab: Sample ID given by the sample provider: Address: Submitting lab: WHO Chinese National Influenza Center Sample ID given by the submitting laboratory: Authors: Address: WHO Chinese National Influenza Center Virology Institute, Chinese CDC 155 Changbai Road, Changping District, Beijing 102206 China Publication Publication In vivo antiviral resistance Phenotype Genotype Unspecified Antiviral resistance tested by experimental procedures Adamantanes: Unknown Oseltamivir: Unknown Zanamivir: Unknown Peramivir: Unknown Other: Unknown Additional information Antigenic characterization: Note: Sequence segment identifier length accession # INSDC Sequence HA A/Environment/Guangdong/C16283277/2016-HA 1695 EPI919623 NA A/Environment/Guangdong/C16283277/2016-NA 1398 EPI919622 Submitter information Submitter: Yang, Lei Submission Date: 2017-02-20 Last modifier: Yang, Lei Last modified: 2017-02-20 Address: WHO Chinese National Influenza Center Virology Institute, Chinese CDC 155 Changbai Road, Changping District, Beijing 102206 China
niman Posted March 3, 2017 Author Report Posted March 3, 2017 Isolate detail Isolate name: A/Environment/Guangdong/KGZ4048/2016(H7,H9,N2,N9) Isolate ID: EPI_ISL_249313 Passage details/history: E1 Type: A Lineage: Sample information Collection date: 2016-12-12 Host Environment Additional host information: Location: China Additional location information: Guangdong Institute information Originating lab: Sample ID given by the sample provider: Address: Submitting lab: WHO Chinese National Influenza Center Sample ID given by the submitting laboratory: Authors: Address: WHO Chinese National Influenza Center Virology Institute, Chinese CDC 155 Changbai Road, Changping District, Beijing 102206 China Publication Publication In vivo antiviral resistance Phenotype Genotype Unspecified Antiviral resistance tested by experimental procedures Adamantanes: Unknown Oseltamivir: Unknown Zanamivir: Unknown Peramivir: Unknown Other: Unknown Additional information Antigenic characterization: Note: Sequence segment identifier length accession # INSDC Sequence HA A/Environment/Guangdong/KGZ4048/2016-HA 1695 EPI919621 NA A/Environment/Guangdong/KGZ4048/2016-NA 1398 EPI919620 Submitter information Submitter: Yang, Lei Submission Date: 2017-02-20 Last modifier: Yang, Lei Last modified: 2017-02-20 Address: WHO Chinese National Influenza Center Virology Institute, Chinese CDC 155 Changbai Road, Changping District, Beijing 102206 China
niman Posted March 3, 2017 Author Report Posted March 3, 2017 Isolate detail Isolate name: A/Environment/Guangdong/KGZ4068/2016(H7,H9,N2,N9) Isolate ID: EPI_ISL_249312 Passage details/history: E1 Type: A Lineage: Sample information Collection date: 2016-12-12 Host Environment Additional host information: Location: China Additional location information: Guangdong Institute information Originating lab: Sample ID given by the sample provider: Address: Submitting lab: WHO Chinese National Influenza Center Sample ID given by the submitting laboratory: Authors: Address: WHO Chinese National Influenza Center Virology Institute, Chinese CDC 155 Changbai Road, Changping District, Beijing 102206 China Publication Publication In vivo antiviral resistance Phenotype Genotype Unspecified Antiviral resistance tested by experimental procedures Adamantanes: Unknown Oseltamivir: Unknown Zanamivir: Unknown Peramivir: Unknown Other: Unknown Additional information Antigenic characterization: Note: Sequence segment identifier length accession # INSDC Sequence HA A/Environment/Guangdong/KGZ4068/2016-HA 1695 EPI919619 NA A/Environment/Guangdong/KGZ4068/2016-NA 1398 EPI919618 Submitter information Submitter: Yang, Lei Submission Date: 2017-02-20 Last modifier: Yang, Lei Last modified: 2017-02-20 Address: WHO Chinese National Influenza Center Virology Institute, Chinese CDC 155 Changbai Road, Changping District, Beijing 102206 China
niman Posted March 3, 2017 Author Report Posted March 3, 2017 Isolate detail Isolate name: A/Environment/Guangdong/KGZ4075/2016(H7,H9,N2,N9) Isolate ID: EPI_ISL_249311 Passage details/history: E1 Type: A Lineage: Sample information Collection date: 2016-12-12 Host Environment Additional host information: Location: China Additional location information: Guangdong Institute information Originating lab: Sample ID given by the sample provider: Address: Submitting lab: WHO Chinese National Influenza Center Sample ID given by the submitting laboratory: Authors: Address: WHO Chinese National Influenza Center Virology Institute, Chinese CDC 155 Changbai Road, Changping District, Beijing 102206 China Publication Publication In vivo antiviral resistance Phenotype Genotype Unspecified Antiviral resistance tested by experimental procedures Adamantanes: Unknown Oseltamivir: Unknown Zanamivir: Unknown Peramivir: Unknown Other: Unknown Additional information Antigenic characterization: Note: Sequence segment identifier length accession # INSDC Sequence HA A/Environment/Guangdong/KGZ4075/2016-HA 1695 EPI919617 NA A/Environment/Guangdong/KGZ4075/2016-NA 1398 EPI919616 Submitter information Submitter: Yang, Lei Submission Date: 2017-02-20 Last modifier: Yang, Lei Last modified: 2017-02-20 Address: WHO Chinese National Influenza Center Virology Institute, Chinese CDC 155 Changbai Road, Changping District, Beijing 102206 China
niman Posted March 3, 2017 Author Report Posted March 3, 2017 Isolate detail Isolate name: A/Environment/Guangdong/C16283222/2016 Isolate ID: EPI_ISL_249310 Passage details/history: E1 Type: A / H7N9 Lineage: Sample information Collection date: 2016-11-07 Host Environment Additional host information: Location: China Additional location information: Guangdong Institute information Originating lab: Sample ID given by the sample provider: Address: Submitting lab: WHO Chinese National Influenza Center Sample ID given by the submitting laboratory: Authors: Address: WHO Chinese National Influenza Center Virology Institute, Chinese CDC 155 Changbai Road, Changping District, Beijing 102206 China Publication Publication In vivo antiviral resistance Phenotype Genotype Unspecified Antiviral resistance tested by experimental procedures Adamantanes: Unknown Oseltamivir: Unknown Zanamivir: Unknown Peramivir: Unknown Other: Unknown Additional information Antigenic characterization: Note: Sequence segment identifier length accession # INSDC Sequence PB2 A/Environment/Guangdong/C16283222/2016-PB2 2280 EPI919612 PB1 A/Environment/Guangdong/C16283222/2016-PB1 2274 EPI919613 PA A/Environment/Guangdong/C16283222/2016-PA 2151 EPI919611 HA A/Environment/Guangdong/C16283222/2016-HA 1695 EPI919615 NP A/Environment/Guangdong/C16283222/2016-NP 1497 EPI919608 NA A/Environment/Guangdong/C16283222/2016-NA 1398 EPI919614 MP A/Environment/Guangdong/C16283222/2016-MP 982 EPI919610 NS A/Environment/Guangdong/C16283222/2016-NS 838 EPI919609 Submitter information Submitter: Yang, Lei Submission Date: 2017-02-20 Last modifier: Yang, Lei Last modified: 2017-02-20 Address: WHO Chinese National Influenza Center Virology Institute, Chinese CDC 155 Changbai Road, Changping District, Beijing 102206 China
niman Posted March 3, 2017 Author Report Posted March 3, 2017 Isolate detail Isolate name: A/Guangdong/17SF003/2016 Isolate ID: EPI_ISL_249309 Passage details/history: E1 Type: A / H7N9 Lineage: Sample information Collection date: 2017-01-03 Host Human Additional host information: Zip code: Patient status: Last vaccinated: In-vivo pathogenicity test: Location: China Additional location information: Guangdong Patient age: 43 Year(s) Gender: Female Outbreak: Treatment: Specimen source: Institute information Originating lab: Sample ID given by the sample provider: Address: Submitting lab: WHO Chinese National Influenza Center Sample ID given by the submitting laboratory: Authors: Address: WHO Chinese National Influenza Center Virology Institute, Chinese CDC 155 Changbai Road, Changping District, Beijing 102206 China Publication Publication In vivo antiviral resistance Phenotype Genotype Unspecified Antiviral resistance tested by experimental procedures Adamantanes: Unknown Oseltamivir: Unknown Zanamivir: Unknown Peramivir: Unknown Other: Unknown Additional information Antigenic characterization: Note: Sequence segment identifier length accession # INSDC Sequence PB2 A/Guangdong/17SF003/2016-PB2 2280 EPI919604 PB1 A/Guangdong/17SF003/2016-PB1 2274 EPI919605 PA A/Guangdong/17SF003/2016-PA 2151 EPI919603 HA A/Guangdong/17SF003/2016-HA 1695 EPI919607 NP A/Guangdong/17SF003/2016-NP 1497 EPI919600 NA A/Guangdong/17SF003/2016-NA 1398 EPI919606 MP A/Guangdong/17SF003/2016-MP 982 EPI919602 NS A/Guangdong/17SF003/2016-NS 838 EPI919601 Submitter information Submitter: Yang, Lei Submission Date: 2017-02-20 Last modifier: Yang, Lei Last modified: 2017-02-21 Address: WHO Chinese National Influenza Center Virology Institute, Chinese CDC 155 Changbai Road, Changping District, Beijing 102206 China
niman Posted March 3, 2017 Author Report Posted March 3, 2017 Isolate detail Isolate name: A/Guangdong/17SF006/2017 Isolate ID: EPI_ISL_249308 Passage details/history: E1 Type: A / H7N9 Lineage: Sample information Collection date: 2017-01-12 Host Human Additional host information: Zip code: Patient status: Last vaccinated: In-vivo pathogenicity test: Location: China Additional location information: Guangdong Patient age: 57 Year(s) Gender: Male Outbreak: Treatment: Specimen source: Institute information Originating lab: Sample ID given by the sample provider: Address: Submitting lab: WHO Chinese National Influenza Center Sample ID given by the submitting laboratory: Authors: Address: WHO Chinese National Influenza Center Virology Institute, Chinese CDC 155 Changbai Road, Changping District, Beijing 102206 China Publication Publication In vivo antiviral resistance Phenotype Genotype Unspecified Antiviral resistance tested by experimental procedures Adamantanes: Unknown Oseltamivir: Unknown Zanamivir: Unknown Peramivir: Unknown Other: Unknown Additional information Antigenic characterization: Note: Sequence segment identifier length accession # INSDC Sequence PB2 A/Guangdong/17SF006/2017-PB2 2280 EPI919596 PB1 A/Guangdong/17SF006/2017-PB1 2274 EPI919597 PA A/Guangdong/17SF006/2017-PA 2151 EPI919595 HA A/Guangdong/17SF006/2017-HA 1695 EPI919599 NP A/Guangdong/17SF006/2017-NP 1497 EPI919592 NA A/Guangdong/17SF006/2017-NA 1398 EPI919598 MP A/Guangdong/17SF006/2017-MP 982 EPI919594 NS A/Guangdong/17SF006/2017-NS 838 EPI919593 Submitter information Submitter: Yang, Lei Submission Date: 2017-02-20 Last modifier: Yang, Lei Last modified: 2017-02-21 Address: WHO Chinese National Influenza Center Virology Institute, Chinese CDC 155 Changbai Road, Changping District, Beijing 102206 China
niman Posted March 3, 2017 Author Report Posted March 3, 2017 Isolate detail Isolate name: A/Fujian/54840/2016 Isolate ID: EPI_ISL_242901 Passage details/history: E1 Type: A / H7N9 Lineage: Sample information Collection date: 2016-11-16 Host Human Additional host information: Zip code: Patient status: Last vaccinated: In-vivo pathogenicity test: Location: China Additional location information: Fujian Patient age: 60 Year(s) Gender: Male Outbreak: Treatment: Specimen source: Institute information Originating lab: Sample ID given by the sample provider: Address: Submitting lab: WHO Chinese National Influenza Center Sample ID given by the submitting laboratory: Authors: Wang,Dayan; Zhou,Shumei; Li,Xiyan; Li,Xiaodan; Zhang,Ye; Bo,Hong; Shu,Yuelong Address: WHO Chinese National Influenza Center Virology Institute, Chinese CDC 155 Changbai Road, Changping District, Beijing 102206 China Publication Publication In vivo antiviral resistance Phenotype Genotype Unspecified Antiviral resistance tested by experimental procedures Adamantanes: Unknown Oseltamivir: Unknown Zanamivir: Unknown Peramivir: Unknown Other: Unknown Additional information Antigenic characterization: Note: Sequence segment identifier length accession # INSDC Sequence PB2 A_FUJIAN_54840_2016_NOV-PB2 2280 EPI888081 PB1 A_FUJIAN_54840_2016_NOV-PB1 2274 EPI888082 PA A_FUJIAN_54840_2016_NOV-PA 2151 EPI888080 HA A_FUJIAN_54840_2016_NOV-HA 1683 EPI888084 NP A_FUJIAN_54840_2016_NOV-NP 1497 EPI888077 NA A_FUJIAN_54840_2016_NOV-NA 1398 EPI888083 MP A_FUJIAN_54840_2016_NOV-MP 982 EPI888079 NS A_FUJIAN_54840_2016_NOV-NS 838 EPI888078 Submitter information Submitter: Yang, Lei Submission Date: 2017-01-25 Last modifier: Yang, Lei Last modified: 2017-01-25 Address: WHO Chinese National Influenza Center Virology Institute, Chinese CDC 155 Changbai Road, Changping District, Beijing 102206 China
niman Posted March 3, 2017 Author Report Posted March 3, 2017 Isolate detail Isolate name: A/Anhui/60926/2016 Isolate ID: EPI_ISL_242900 Passage details/history: E1 Type: A / H7N9 Lineage: Sample information Collection date: 2016-12-21 Host Human Additional host information: Zip code: Patient status: Last vaccinated: In-vivo pathogenicity test: Location: China Additional location information: Anhui Patient age: 66 Year(s) Gender: Female Outbreak: Treatment: Specimen source: Institute information Originating lab: Sample ID given by the sample provider: Address: Submitting lab: WHO Chinese National Influenza Center Sample ID given by the submitting laboratory: Authors: Wang,Dayan; Zhou,Shumei; Li,Xiyan; Li,Xiaodan; Zhang,Ye; Bo,Hong; Shu,Yuelong Address: WHO Chinese National Influenza Center Virology Institute, Chinese CDC 155 Changbai Road, Changping District, Beijing 102206 China Publication Publication In vivo antiviral resistance Phenotype Genotype Unspecified Antiviral resistance tested by experimental procedures Adamantanes: Unknown Oseltamivir: Unknown Zanamivir: Unknown Peramivir: Unknown Other: Unknown Additional information Antigenic characterization: Note: Sequence segment identifier length accession # INSDC Sequence PB2 A_ANHUI_60926_2016_DEC-PB2 2280 EPI888073 PB1 A_ANHUI_60926_2016_DEC-PB1 2274 EPI888074 PA A_ANHUI_60926_2016_DEC-PA 2151 EPI888072 HA A_ANHUI_60926_2016_DEC-HA 1683 EPI888076 NP A_ANHUI_60926_2016_DEC-NP 1497 EPI888069 NA A_ANHUI_60926_2016_DEC-NA 1398 EPI888075 MP A_ANHUI_60926_2016_DEC-MP 982 EPI888071 NS A_ANHUI_60926_2016_DEC-NS 838 EPI888070 Submitter information Submitter: Yang, Lei Submission Date: 2017-01-25 Last modifier: Yang, Lei Last modified: 2017-01-25 Address: WHO Chinese National Influenza Center Virology Institute, Chinese CDC 155 Changbai Road, Changping District, Beijing 102206 China
niman Posted March 3, 2017 Author Report Posted March 3, 2017 Isolate detail Isolate name: A/Jiangsu/60452/2016 Isolate ID: EPI_ISL_242899 Passage details/history: E1 Type: A / H7N9 Lineage: Sample information Collection date: 2016-12-19 Host Human Additional host information: Zip code: Patient status: Last vaccinated: In-vivo pathogenicity test: Location: China Additional location information: Jiangsu Patient age: 46 Year(s) Gender: Female Outbreak: Treatment: Specimen source: Institute information Originating lab: Sample ID given by the sample provider: Address: Submitting lab: WHO Chinese National Influenza Center Sample ID given by the submitting laboratory: Authors: Wang,Dayan; Zhou,Shumei; Li,Xiyan; Li,Xiaodan; Zhang,Ye; Bo,Hong; Shu,Yuelong Address: WHO Chinese National Influenza Center Virology Institute, Chinese CDC 155 Changbai Road, Changping District, Beijing 102206 China Publication Publication In vivo antiviral resistance Phenotype Genotype Unspecified Antiviral resistance tested by experimental procedures Adamantanes: Unknown Oseltamivir: Unknown Zanamivir: Unknown Peramivir: Unknown Other: Unknown Additional information Antigenic characterization: Note: Sequence segment identifier length accession # INSDC Sequence PB2 A_JIANGSU_60452_2016_DEC-PB2 2280 EPI888065 PB1 A_JIANGSU_60452_2016_DEC-PB1 2274 EPI888066 PA A_JIANGSU_60452_2016_DEC-PA 2151 EPI888064 HA A_JIANGSU_60452_2016_DEC-HA 1683 EPI888068 NP A_JIANGSU_60452_2016_DEC-NP 1497 EPI888061 NA A_JIANGSU_60452_2016_DEC-NA 1398 EPI888067 MP A_JIANGSU_60452_2016_DEC-MP 982 EPI888063 NS A_JIANGSU_60452_2016_DEC-NS 838 EPI888062 Submitter information Submitter: Yang, Lei Submission Date: 2017-01-25 Last modifier: Yang, Lei Last modified: 2017-01-25 Address: WHO Chinese National Influenza Center Virology Institute, Chinese CDC 155 Changbai Road, Changping District, Beijing 102206 China
niman Posted March 3, 2017 Author Report Posted March 3, 2017 Isolate detail Isolate name: A/Anhui/60935/2016 Isolate ID: EPI_ISL_242898 Passage details/history: E1 Type: A / H7N9 Lineage: Sample information Collection date: 2016-12-19 Host Human Additional host information: Zip code: Patient status: Last vaccinated: In-vivo pathogenicity test: Location: China Additional location information: Anhui Patient age: 37 Year(s) Gender: Female Outbreak: Treatment: Specimen source: Institute information Originating lab: Sample ID given by the sample provider: Address: Submitting lab: WHO Chinese National Influenza Center Sample ID given by the submitting laboratory: Authors: Wang,Dayan; Zhou,Shumei; Li,Xiyan; Li,Xiaodan; Zhang,Ye; Bo,Hong; Shu,Yuelong Address: WHO Chinese National Influenza Center Virology Institute, Chinese CDC 155 Changbai Road, Changping District, Beijing 102206 China Publication Publication In vivo antiviral resistance Phenotype Genotype Unspecified Antiviral resistance tested by experimental procedures Adamantanes: Unknown Oseltamivir: Unknown Zanamivir: Unknown Peramivir: Unknown Other: Unknown Additional information Antigenic characterization: Note: Sequence segment identifier length accession # INSDC Sequence PB2 A_ANHUI_60935_2016_DEC-PB2 2280 EPI888057 PB1 A_ANHUI_60935_2016_DEC-PB1 2274 EPI888058 PA A_ANHUI_60935_2016_DEC-PA 2151 EPI888056 HA A_ANHUI_60935_2016_DEC-HA 1683 EPI888060 NP A_ANHUI_60935_2016_DEC-NP 1497 EPI888053 NA A_ANHUI_60935_2016_DEC-NA 1398 EPI888059 MP A_ANHUI_60935_2016_DEC-MP 982 EPI888055 NS A_ANHUI_60935_2016_DEC-NS 838 EPI888054 Submitter information Submitter: Yang, Lei Submission Date: 2017-01-25 Last modifier: Yang, Lei Last modified: 2017-01-25 Address: WHO Chinese National Influenza Center Virology Institute, Chinese CDC 155 Changbai Road, Changping District, Beijing 102206 China
niman Posted March 3, 2017 Author Report Posted March 3, 2017 Isolate detail Isolate name: A/Anhui/60934/2016 Isolate ID: EPI_ISL_242897 Passage details/history: E1 Type: A / H7N9 Lineage: Sample information Collection date: 2016-12-19 Host Human Additional host information: Zip code: Patient status: Last vaccinated: In-vivo pathogenicity test: Location: China Additional location information: Anhui Patient age: 37 Year(s) Gender: Female Outbreak: Treatment: Specimen source: Institute information Originating lab: Sample ID given by the sample provider: Address: Submitting lab: WHO Chinese National Influenza Center Sample ID given by the submitting laboratory: Authors: Wang,Dayan; Zhou,Shumei; Li,Xiyan; Li,Xiaodan; Zhang,Ye; Bo,Hong; Shu,Yuelong Address: WHO Chinese National Influenza Center Virology Institute, Chinese CDC 155 Changbai Road, Changping District, Beijing 102206 China Publication Publication In vivo antiviral resistance Phenotype Genotype Unspecified Antiviral resistance tested by experimental procedures Adamantanes: Unknown Oseltamivir: Unknown Zanamivir: Unknown Peramivir: Unknown Other: Unknown Additional information Antigenic characterization: Note: Sequence segment identifier length accession # INSDC Sequence PB2 A_ANHUI_60934_2016_DEC-PB2 2280 EPI888049 PB1 A_ANHUI_60934_2016_DEC-PB1 2274 EPI888050 PA A_ANHUI_60934_2016_DEC-PA 2151 EPI888048 HA A_ANHUI_60934_2016_DEC-HA 1683 EPI888052 NP A_ANHUI_60934_2016_DEC-NP 1497 EPI888045 NA A_ANHUI_60934_2016_DEC-NA 1398 EPI888051 MP A_ANHUI_60934_2016_DEC-MP 982 EPI888047 NS A_ANHUI_60934_2016_DEC-NS 838 EPI888046 Submitter information Submitter: Yang, Lei Submission Date: 2017-01-25 Last modifier: Yang, Lei Last modified: 2017-01-25 Address: WHO Chinese National Influenza Center Virology Institute, Chinese CDC 155 Changbai Road, Changping District, Beijing 102206 China
niman Posted March 3, 2017 Author Report Posted March 3, 2017 Isolate detail Isolate name: A/Anhui/60933/2016 Isolate ID: EPI_ISL_242896 Passage details/history: E1 Type: A / H7N9 Lineage: Sample information Collection date: 2016-12-19 Host Human Additional host information: Zip code: Patient status: Last vaccinated: In-vivo pathogenicity test: Location: China Additional location information: Anhui Patient age: 66 Year(s) Gender: Male Outbreak: Treatment: Specimen source: Institute information Originating lab: Sample ID given by the sample provider: Address: Submitting lab: WHO Chinese National Influenza Center Sample ID given by the submitting laboratory: Authors: Wang,Dayan; Zhou,Shumei; Li,Xiyan; Li,Xiaodan; Zhang,Ye; Bo,Hong; Shu,Yuelong Address: WHO Chinese National Influenza Center Virology Institute, Chinese CDC 155 Changbai Road, Changping District, Beijing 102206 China Publication Publication In vivo antiviral resistance Phenotype Genotype Unspecified Antiviral resistance tested by experimental procedures Adamantanes: Unknown Oseltamivir: Unknown Zanamivir: Unknown Peramivir: Unknown Other: Unknown Additional information Antigenic characterization: Note: Sequence segment identifier length accession # INSDC Sequence PB2 A_ANHUI_60933_2016_DEC-PB2 2280 EPI888041 PB1 A_ANHUI_60933_2016_DEC-PB1 2274 EPI888042 PA A_ANHUI_60933_2016_DEC-PA 2151 EPI888040 HA A_ANHUI_60933_2016_DEC-HA 1683 EPI888044 NP A_ANHUI_60933_2016_DEC-NP 1497 EPI888037 NA A_ANHUI_60933_2016_DEC-NA 1398 EPI888043 MP A_ANHUI_60933_2016_DEC-MP 982 EPI888039 NS A_ANHUI_60933_2016_DEC-NS 838 EPI888038 Submitter information Submitter: Yang, Lei Submission Date: 2017-01-25 Last modifier: Yang, Lei Last modified: 2017-01-25 Address: WHO Chinese National Influenza Center Virology Institute, Chinese CDC 155 Changbai Road, Changping District, Beijing 102206 China
niman Posted March 3, 2017 Author Report Posted March 3, 2017 Isolate detail Isolate name: A/Anhui/60933/2016 Isolate ID: EPI_ISL_242896 Passage details/history: E1 Type: A / H7N9 Lineage: Sample information Collection date: 2016-12-19 Host Human Additional host information: Zip code: Patient status: Last vaccinated: In-vivo pathogenicity test: Location: China Additional location information: Anhui Patient age: 66 Year(s) Gender: Male Outbreak: Treatment: Specimen source: Institute information Originating lab: Sample ID given by the sample provider: Address: Submitting lab: WHO Chinese National Influenza Center Sample ID given by the submitting laboratory: Authors: Wang,Dayan; Zhou,Shumei; Li,Xiyan; Li,Xiaodan; Zhang,Ye; Bo,Hong; Shu,Yuelong Address: WHO Chinese National Influenza Center Virology Institute, Chinese CDC 155 Changbai Road, Changping District, Beijing 102206 China Publication Publication In vivo antiviral resistance Phenotype Genotype Unspecified Antiviral resistance tested by experimental procedures Adamantanes: Unknown Oseltamivir: Unknown Zanamivir: Unknown Peramivir: Unknown Other: Unknown Additional information Antigenic characterization: Note: Sequence segment identifier length accession # INSDC Sequence PB2 A_ANHUI_60933_2016_DEC-PB2 2280 EPI888041 PB1 A_ANHUI_60933_2016_DEC-PB1 2274 EPI888042 PA A_ANHUI_60933_2016_DEC-PA 2151 EPI888040 HA A_ANHUI_60933_2016_DEC-HA 1683 EPI888044 NP A_ANHUI_60933_2016_DEC-NP 1497 EPI888037 NA A_ANHUI_60933_2016_DEC-NA 1398 EPI888043 MP A_ANHUI_60933_2016_DEC-MP 982 EPI888039 NS A_ANHUI_60933_2016_DEC-NS 838 EPI888038 Submitter information Submitter: Yang, Lei Submission Date: 2017-01-25 Last modifier: Yang, Lei Last modified: 2017-01-25 Address: WHO Chinese National Influenza Center Virology Institute, Chinese CDC 155 Changbai Road, Changping District, Beijing 102206 China
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