Media Myth On Tamiflu Resistance In HPAI H7N9

niman · March 3, 2017

Isolate detail

Isolate name:

A/Anhui/60931/2016

Isolate ID:

EPI_ISL_242895

Passage details/history:

E1

Type:

A / H7N9

Lineage:

Sample information

Collection date:

2016-12-13

Host

Human

Additional host information:

Zip code:

Patient status:

Last vaccinated:

In-vivo pathogenicity test:

Location:

China

Additional location information:

Anhui

Patient age:

73 Year(s)

Gender:

Male

Outbreak:

Treatment:

Specimen source:

Institute information

Originating lab:

Sample ID given by the sample provider:

Address:

Submitting lab:

WHO Chinese National Influenza Center

Sample ID given by the submitting laboratory:

Authors:

Wang,Dayan;
Zhou,Shumei;
Li,Xiyan;
Li,Xiaodan;
Zhang,Ye;
Bo,Hong;
Shu,Yuelong

Address:

WHO Chinese National Influenza Center
Virology Institute, Chinese CDC
 155 Changbai Road, Changping District,  
Beijing 102206
China

Publication

In vivo antiviral resistance

Antiviral resistance tested by experimental procedures

Adamantanes:

Unknown

Oseltamivir:

Unknown

Zanamivir:

Unknown

Peramivir:

Unknown

Other:

Unknown

Additional information

Antigenic characterization:

Note:

Sequence

segment	identifier	length	accession #
PB2	A_ANHUI_60931_2016_DEC-PB2	2280	EPI888033
PB1	A_ANHUI_60931_2016_DEC-PB1	2274	EPI888034
PA	A_ANHUI_60931_2016_DEC-PA	2151	EPI888032
HA	A_ANHUI_60931_2016_DEC-HA	1683	EPI888036
NP	A_ANHUI_60931_2016_DEC-NP	1497	EPI888029
NA	A_ANHUI_60931_2016_DEC-NA	1398	EPI888035
MP	A_ANHUI_60931_2016_DEC-MP	982	EPI888031
NS	A_ANHUI_60931_2016_DEC-NS	838	EPI888030

Submitter information

Submitter:

Yang, Lei

Submission Date:

2017-01-25

Last modifier:

Yang, Lei

Last modified:

2017-01-25

Address:

WHO Chinese National Influenza Center
Virology Institute, Chinese CDC
 155 Changbai Road, Changping District,  
Beijing 102206
China

niman · March 3, 2017

Isolate detail

Isolate name:

A/Anhui/60932/2016

Isolate ID:

EPI_ISL_242894

Passage details/history:

E1

Type:

A / H7N9

Lineage:

Sample information

Collection date:

2016-12-19

Host

Human

Additional host information:

Zip code:

Patient status:

Last vaccinated:

In-vivo pathogenicity test:

Location:

China

Additional location information:

Anhui

Patient age:

60 Year(s)

Gender:

Male

Outbreak:

Treatment:

Specimen source:

Institute information

Originating lab:

Sample ID given by the sample provider:

Address:

Submitting lab:

WHO Chinese National Influenza Center

Sample ID given by the submitting laboratory:

Authors:

Wang,Dayan;
Zhou,Shumei;
Li,Xiyan;
Li,Xiaodan;
Zhang,Ye;
Bo,Hong;
Shu,Yuelong

Address:

WHO Chinese National Influenza Center
Virology Institute, Chinese CDC
 155 Changbai Road, Changping District,  
Beijing 102206
China

Publication

In vivo antiviral resistance

Antiviral resistance tested by experimental procedures

Adamantanes:

Unknown

Oseltamivir:

Unknown

Zanamivir:

Unknown

Peramivir:

Unknown

Other:

Unknown

Additional information

Antigenic characterization:

Note:

Sequence

segment	identifier	length	accession #
PB2	A_ANHUI_60932_2016_DEC-PB2	2280	EPI888025
PB1	A_ANHUI_60932_2016_DEC-PB1	2274	EPI888026
PA	A_ANHUI_60932_2016_DEC-PA	2151	EPI888024
HA	A_ANHUI_60932_2016_DEC-HA	1683	EPI888028
NP	A_ANHUI_60932_2016_DEC-NP	1497	EPI888021
NA	A_ANHUI_60932_2016_DEC-NA	1398	EPI888027
MP	A_ANHUI_60932_2016_DEC-MP	982	EPI888023
NS	A_ANHUI_60932_2016_DEC-NS	838	EPI888022

Submitter information

Submitter:

Yang, Lei

Submission Date:

2017-01-25

Last modifier:

Yang, Lei

Last modified:

2017-01-25

Address:

WHO Chinese National Influenza Center
Virology Institute, Chinese CDC
 155 Changbai Road, Changping District,  
Beijing 102206
China

niman · March 3, 2017

Isolate detail

Isolate name:

A/Anhui/60929/2016

Isolate ID:

EPI_ISL_242893

Passage details/history:

E1

Type:

A / H7N9

Lineage:

Sample information

Collection date:

2016-12-15

Host

Human

Additional host information:

Zip code:

Patient status:

Last vaccinated:

In-vivo pathogenicity test:

Location:

China

Additional location information:

Anhui

Patient age:

65 Year(s)

Gender:

Male

Outbreak:

Treatment:

Specimen source:

Institute information

Originating lab:

Sample ID given by the sample provider:

Address:

Submitting lab:

WHO Chinese National Influenza Center

Sample ID given by the submitting laboratory:

Authors:

Wang,Dayan;
Zhou,Shumei;
Li,Xiyan;
Li,Xiaodan;
Zhang,Ye;
Bo,Hong;
Shu,Yuelong

Address:

WHO Chinese National Influenza Center
Virology Institute, Chinese CDC
 155 Changbai Road, Changping District,  
Beijing 102206
China

Publication

In vivo antiviral resistance

Antiviral resistance tested by experimental procedures

Adamantanes:

Unknown

Oseltamivir:

Unknown

Zanamivir:

Unknown

Peramivir:

Unknown

Other:

Unknown

Additional information

Antigenic characterization:

Note:

Sequence

segment	identifier	length	accession #
PB2	A_ANHUI_60929_2016_DEC-PB2	2280	EPI888017
PB1	A_ANHUI_60929_2016_DEC-PB1	2274	EPI888018
PA	A_ANHUI_60929_2016_DEC-PA	2151	EPI888016
HA	A_ANHUI_60929_2016_DEC-HA	1683	EPI888020
NP	A_ANHUI_60929_2016_DEC-NP	1497	EPI888013
NA	A_ANHUI_60929_2016_DEC-NA	1398	EPI888019
MP	A_ANHUI_60929_2016_DEC-MP	982	EPI888015
NS	A_ANHUI_60929_2016_DEC-NS	838	EPI888014

Submitter information

Submitter:

Yang, Lei

Submission Date:

2017-01-25

Last modifier:

Yang, Lei

Last modified:

2017-01-25

Address:

WHO Chinese National Influenza Center
Virology Institute, Chinese CDC
 155 Changbai Road, Changping District,  
Beijing 102206
China

niman · March 3, 2017

Isolate detail

Isolate name:

A/Anhui/60925/2016

Isolate ID:

EPI_ISL_242891

Passage details/history:

E1

Type:

A / H7N9

Lineage:

Sample information

Collection date:

2016-12-21

Host

Human

Additional host information:

Zip code:

Patient status:

Last vaccinated:

In-vivo pathogenicity test:

Location:

China

Additional location information:

Anhui

Patient age:

66 Year(s)

Gender:

Female

Outbreak:

Treatment:

Specimen source:

Institute information

Originating lab:

Sample ID given by the sample provider:

Address:

Submitting lab:

WHO Chinese National Influenza Center

Sample ID given by the submitting laboratory:

Authors:

Wang,Dayan;
Zhou,Shumei;
Li,Xiyan;
Li,Xiaodan;
Zhang,Ye;
Bo,Hong;
Shu,Yuelong

Address:

WHO Chinese National Influenza Center
Virology Institute, Chinese CDC
 155 Changbai Road, Changping District,  
Beijing 102206
China

Publication

In vivo antiviral resistance

Antiviral resistance tested by experimental procedures

Adamantanes:

Unknown

Oseltamivir:

Unknown

Zanamivir:

Unknown

Peramivir:

Unknown

Other:

Unknown

Additional information

Antigenic characterization:

Note:

Sequence

segment	identifier	length	accession #
PB2	A_ANHUI_60925_2016_DEC-PB2	2280	EPI888001
PB1	A_ANHUI_60925_2016_DEC-PB1	2274	EPI888002
PA	A_ANHUI_60925_2016_DEC-PA	2151	EPI888000
HA	A_ANHUI_60925_2016_DEC-HA	1683	EPI888004
NP	A_ANHUI_60925_2016_DEC-NP	1497	EPI887997
NA	A_ANHUI_60925_2016_DEC-NA	1398	EPI888003
MP	A_ANHUI_60925_2016_DEC-MP	982	EPI887999
NS	A_ANHUI_60925_2016_DEC-NS	838	EPI887998

Submitter information

Submitter:

Yang, Lei

Submission Date:

2017-01-25

Last modifier:

Yang, Lei

Last modified:

2017-01-25

Address:

WHO Chinese National Influenza Center
Virology Institute, Chinese CDC
 155 Changbai Road, Changping District,  
Beijing 102206
China

niman · March 3, 2017

Isolate detail

Isolate name:

A/Anhui/60928/2016

Isolate ID:

EPI_ISL_242892

Passage details/history:

E1

Type:

A / H7N9

Lineage:

Sample information

Collection date:

2016-12-15

Host

Human

Additional host information:

Zip code:

Patient status:

Last vaccinated:

In-vivo pathogenicity test:

Location:

China

Additional location information:

Anhui

Patient age:

Gender:

Outbreak:

Treatment:

Specimen source:

Institute information

Originating lab:

Sample ID given by the sample provider:

Address:

Submitting lab:

WHO Chinese National Influenza Center

Sample ID given by the submitting laboratory:

Authors:

Wang,Dayan;
Zhou,Shumei;
Li,Xiyan;
Li,Xiaodan;
Zhang,Ye;
Bo,Hong;
Shu,Yuelong

Address:

WHO Chinese National Influenza Center
Virology Institute, Chinese CDC
 155 Changbai Road, Changping District,  
Beijing 102206
China

Publication

In vivo antiviral resistance

Antiviral resistance tested by experimental procedures

Adamantanes:

Unknown

Oseltamivir:

Unknown

Zanamivir:

Unknown

Peramivir:

Unknown

Other:

Unknown

Additional information

Antigenic characterization:

Note:

Sequence

segment	identifier	length	accession #
PB2	A_ANHUI_60928_2016_DEC-PB2	2280	EPI888009
PB1	A_ANHUI_60928_2016_DEC-PB1	2274	EPI888010
PA	A_ANHUI_60928_2016_DEC-PA	2151	EPI888008
HA	A_ANHUI_60928_2016_DEC-HA	1683	EPI888012
NP	A_ANHUI_60928_2016_DEC-NP	1497	EPI888005
NA	A_ANHUI_60928_2016_DEC-NA	1398	EPI888011
MP	A_ANHUI_60928_2016_DEC-MP	982	EPI888007
NS	A_ANHUI_60928_2016_DEC-NS	838	EPI888006

Submitter information

Submitter:

Yang, Lei

Submission Date:

2017-01-25

Last modifier:

Yang, Lei

Last modified:

2017-01-25

Address:

WHO Chinese National Influenza Center
Virology Institute, Chinese CDC
 155 Changbai Road, Changping District,  
Beijing 102206
China

niman · March 3, 2017

Isolate detail

Isolate name:

A/Anhui/60924/2016

Isolate ID:

EPI_ISL_242890

Passage details/history:

E1

Type:

A / H7N9

Lineage:

Sample information

Collection date:

2016-12-22

Host

Human

Additional host information:

Zip code:

Patient status:

Last vaccinated:

In-vivo pathogenicity test:

Location:

China

Additional location information:

Anhui

Patient age:

55 Year(s)

Gender:

Female

Outbreak:

Treatment:

Specimen source:

Institute information

Originating lab:

Sample ID given by the sample provider:

Address:

Submitting lab:

WHO Chinese National Influenza Center

Sample ID given by the submitting laboratory:

Authors:

Wang,Dayan;
Zhou,Shumei;
Li,Xiyan;
Li,Xiaodan;
Zhang,Ye;
Bo,Hong;
Shu,Yuelong

Address:

WHO Chinese National Influenza Center
Virology Institute, Chinese CDC
 155 Changbai Road, Changping District,  
Beijing 102206
China

Publication

In vivo antiviral resistance

Antiviral resistance tested by experimental procedures

Adamantanes:

Unknown

Oseltamivir:

Unknown

Zanamivir:

Unknown

Peramivir:

Unknown

Other:

Unknown

Additional information

Antigenic characterization:

Note:

Sequence

segment	identifier	length	accession #
PB2	A_ANHUI_60924_2016_DEC-PB2	2280	EPI887993
PB1	A_ANHUI_60924_2016_DEC-PB1	2274	EPI887994
PA	A_ANHUI_60924_2016_DEC-PA	2151	EPI887992
HA	A_ANHUI_60924_2016_DEC-HA	1683	EPI887996
NP	A_ANHUI_60924_2016_DEC-NP	1497	EPI887989
NA	A_ANHUI_60924_2016_DEC-NA	1398	EPI887995
MP	A_ANHUI_60924_2016_DEC-MP	982	EPI887991
NS	A_ANHUI_60924_2016_DEC-NS	838	EPI887990

Submitter information

Submitter:

Yang, Lei

Submission Date:

2017-01-25

Last modifier:

Yang, Lei

Last modified:

2017-01-25

Address:

WHO Chinese National Influenza Center
Virology Institute, Chinese CDC
 155 Changbai Road, Changping District,  
Beijing 102206
China

niman · March 3, 2017

Isolate detail

Isolate name:

A/Anhui/60927/2016

Isolate ID:

EPI_ISL_242889

Passage details/history:

E1

Type:

A / H7N9

Lineage:

Sample information

Collection date:

2016-12-18

Host

Human

Additional host information:

Zip code:

Patient status:

Last vaccinated:

In-vivo pathogenicity test:

Location:

China

Additional location information:

Anhui

Patient age:

53 Year(s)

Gender:

Male

Outbreak:

Treatment:

Specimen source:

Institute information

Originating lab:

Sample ID given by the sample provider:

Address:

Submitting lab:

WHO Chinese National Influenza Center

Sample ID given by the submitting laboratory:

Authors:

Wang,Dayan;
Zhou,Shumei;
Li,Xiyan;
Li,Xiaodan;
Zhang,Ye;
Bo,Hong;
Shu,Yuelong

Address:

WHO Chinese National Influenza Center
Virology Institute, Chinese CDC
 155 Changbai Road, Changping District,  
Beijing 102206
China

Publication

In vivo antiviral resistance

Antiviral resistance tested by experimental procedures

Adamantanes:

Unknown

Oseltamivir:

Unknown

Zanamivir:

Unknown

Peramivir:

Unknown

Other:

Unknown

Additional information

Antigenic characterization:

Note:

Sequence

segment	identifier	length	accession #
PB2	A_ANHUI_60927_2016_DEC-PB2	2280	EPI887985
PB1	A_ANHUI_60927_2016_DEC-PB1	2274	EPI887986
PA	A_ANHUI_60927_2016_DEC-PA	2151	EPI887984
HA	A_ANHUI_60927_2016_DEC-HA	1683	EPI887988
NP	A_ANHUI_60927_2016_DEC-NP	1497	EPI887981
NA	A_ANHUI_60927_2016_DEC-NA	1398	EPI887987
MP	A_ANHUI_60927_2016_DEC-MP	982	EPI887983
NS	A_ANHUI_60927_2016_DEC-NS	838	EPI887982

Submitter information

Submitter:

Yang, Lei

Submission Date:

2017-01-25

Last modifier:

Yang, Lei

Last modified:

2017-01-25

Address:

WHO Chinese National Influenza Center
Virology Institute, Chinese CDC
 155 Changbai Road, Changping District,  
Beijing 102206
China

niman · March 3, 2017

Isolate detail

Isolate name:

A/Guangdong/60061/2016

Isolate ID:

EPI_ISL_242888

Passage details/history:

E1

Type:

A / H7N9

Lineage:

Sample information

Collection date:

2016-12-13

Host

Human

Additional host information:

Zip code:

Patient status:

Last vaccinated:

In-vivo pathogenicity test:

Location:

China

Additional location information:

Guangdong

Patient age:

49 Year(s)

Gender:

Male

Outbreak:

Treatment:

Specimen source:

Institute information

Originating lab:

Guandong Centers for Disease Control

Sample ID given by the sample provider:

Address:

Guandong Centers for Disease Control
 176 Xingang Western Road ,  
Guangzhou 
China

Submitting lab:

WHO Chinese National Influenza Center

Sample ID given by the submitting laboratory:

Authors:

Wang,Dayan;
Zhou,Shumei;
Li,Xiyan;
Li,Xiaodan;
Zhang,Ye;
Bo,Hong;
Shu,Yuelong

Address:

WHO Chinese National Influenza Center
Virology Institute, Chinese CDC
 155 Changbai Road, Changping District,  
Beijing 102206
China

Publication

In vivo antiviral resistance

Antiviral resistance tested by experimental procedures

Adamantanes:

Unknown

Oseltamivir:

Unknown

Zanamivir:

Unknown

Peramivir:

Unknown

Other:

Unknown

Additional information

Antigenic characterization:

Note:

Sequence

segment	identifier	length	accession #
PB2	A_GUANGDONG_60061_2016_DEC-PB2	2280	EPI887977
PB1	A_GUANGDONG_60061_2016_DEC-PB1	2274	EPI887978
PA	A_GUANGDONG_60061_2016_DEC-PA	2151	EPI887976
HA	A_GUANGDONG_60061_2016_DEC-HA	1683	EPI887980
NP	A_GUANGDONG_60061_2016_DEC-NP	1497	EPI887973
NA	A_GUANGDONG_60061_2016_DEC-NA	1398	EPI887979
MP	A_GUANGDONG_60061_2016_DEC-MP	982	EPI887975
NS	A_GUANGDONG_60061_2016_DEC-NS	838	EPI887974

Submitter information

Submitter:

Yang, Lei

Submission Date:

2017-01-25

Last modifier:

Yang, Lei

Last modified:

2017-01-25

Address:

WHO Chinese National Influenza Center
Virology Institute, Chinese CDC
 155 Changbai Road, Changping District,  
Beijing 102206
China

niman · March 3, 2017

Isolate detail

Isolate name:

A/Jiangsu/60447/2016

Isolate ID:

EPI_ISL_242887

Passage details/history:

E1

Type:

A / H7N9

Lineage:

Sample information

Collection date:

2016-12-16

Host

Human

Additional host information:

Zip code:

Patient status:

Last vaccinated:

In-vivo pathogenicity test:

Location:

China

Additional location information:

Jiangsu

Patient age:

73 Year(s)

Gender:

Female

Outbreak:

Treatment:

Specimen source:

Institute information

Originating lab:

Sample ID given by the sample provider:

Address:

Submitting lab:

WHO Chinese National Influenza Center

Sample ID given by the submitting laboratory:

Authors:

Wang,Dayan;
Zhou,Shumei;
Li,Xiyan;
Li,Xiaodan;
Zhang,Ye;
Bo,Hong;
Shu,Yuelong

Address:

WHO Chinese National Influenza Center
Virology Institute, Chinese CDC
 155 Changbai Road, Changping District,  
Beijing 102206
China

Publication

In vivo antiviral resistance

Antiviral resistance tested by experimental procedures

Adamantanes:

Unknown

Oseltamivir:

Unknown

Zanamivir:

Unknown

Peramivir:

Unknown

Other:

Unknown

Additional information

Antigenic characterization:

Note:

Sequence

segment	identifier	length	accession #
PB2	A_JIANGSU_60447_2016_DEC-PB2	2280	EPI887969
PB1	A_JIANGSU_60447_2016_DEC-PB1	2274	EPI887970
PA	A_JIANGSU_60447_2016_DEC-PA	2151	EPI887968
HA	A_JIANGSU_60447_2016_DEC-HA	1683	EPI887972
NP	A_JIANGSU_60447_2016_DEC-NP	1497	EPI887965
NA	A_JIANGSU_60447_2016_DEC-NA	1398	EPI887971
MP	A_JIANGSU_60447_2016_DEC-MP	982	EPI887967
NS	A_JIANGSU_60447_2016_DEC-NS	838	EPI887966

Submitter information

Submitter:

Yang, Lei

Submission Date:

2017-01-25

Last modifier:

Yang, Lei

Last modified:

2017-01-25

Address:

WHO Chinese National Influenza Center
Virology Institute, Chinese CDC
 155 Changbai Road, Changping District,  
Beijing 102206
China

Admin · March 3, 2017

HEALTH

MAR 3 2017, 5:56 PM ET

CDC Concerned by H7N9 Bird Flu’s Sudden Spread in China

by MAGGIE FOX

A sudden surge in cases of H7N9 bird flu in China is a "cause for concern," the Centers for Disease Control and Prevention said Friday.

It's infected 460 people just since October, the CDC said in a report. "It's by far the largest epidemic wave since 2013," said CDC flu expert Dr. Tim Uyeki.

Image: Health officials in protective suits put a goose into a sack as part of preventive measures against the H7N9 bird flu at a poultry market in Zhuji — Health officials in protective suits put a goose into a sack as part of preventive measures against the H7N9 bird flu at a poultry market in Zhuji, Zhejiang province on Jan. 5, 2014. Reuters file

The CDC has been working on a vaccine against H7N9 just in case it's ever needed and is starting work on a second one now because it's started to mutate.

"It's a cause for concern, that's for sure," Uyeki told NBC News. "The surge in numbers of human H7N9 cases in China is definitely a concern."

The CDC issued a travel notice in January, cautioning travelers to China to stay away from live bird markets. Uyeki said travelers do not need to avoid China but they should be aware that poultry can spread the virus.

Related: WHO Says Watch Out for Bird Flu

Since 2013, H7N9 bird flu has infected 1,258 people, the CDC said. So 460 cases in just five months account for a third of all the cases over four years.

Earlier this week the World Health Organization held a meeting on H7N9 and then issued public reassurances, saying the virus did not appear to have changed in a way that would make it more likely to spread to people or to make it more dangerous to people.

Instead, the changes make the virus more dangerous to birds — which could be a good thing.

"These changes make the virus highly pathogenic in birds, meaning that it can cause some severe disease in birds," Dr. Wenqing Zhang, head of WHO's global influenza program, told reporters.

"Previously, H7N9 had only been observed to be 'low pathogenic' in birds, meaning the virus did not cause visible outbreaks of disease in birds," Zhang said.

If an avian influenza virus kills birds, it's bad for poultry farmers but it can give a warning that the virus is spreading. The problem with H7N9 has been that it does not make poultry sick, so it can spread among flocks without people knowing it.

Uyeki is worried that H7N9 has become more widespread in China, spreading silently and infecting more people because it's infecting more birds.

"You could have more cases of human infection even if the risk of poultry-to-human transmission has not changed," he said.

China has been publishing genetic sequences of the H7N9 virus in public databases, but it has not been sharing actual samples of the virus, so it's not possible for U.S. labs to test the virus themselves to see whether it's changed and if so, whether it's more dangerous.

But it's already dangerous. H7N9 is considered a moderate to high pandemic threat, although the CDC and WHO do not think an H7N9 pandemic is about to happen, or even that it is certain to happen.

Related: CDC Issues H7N9 Travel Warning

H7N9 is one of several strains of bird flu that officials are watching because they have the potential to cause a human pandemic.

So far, H7N9 doesn't seem to infect people easily and people who are infected do not seem to spread it to others much. But influenza viruses change quickly and unpredictably, and if one starts passing easily from one person to another it could spread.

"From what we understand, there have been no real changes in the epidemiology or mortality of hospitalized H7N9 cases," Uyeki said.

H7N9 can be deadly when people do get it. It kills more than 40 percent of people who get sick enough to go to the hospital.

Related: H7N9 has cost billions

"Early symptoms are similar to those of seasonal flu and may include fever, cough, sore throat, muscle aches and fatigue, loss of appetite, and runny or stuffy nose," CDC said.

It often progresses to pneumonia. And hospitals or clinics treating people infected with H7N9 need to take precautions to make sure patients do not infect anyone else.

"Clinicians should consider the possibility of avian influenza A (H7N9) virus infection in people presenting with respiratory illness within 10 days of travel to China, particularly if the patient reports exposure to birds or poultry markets," the CDC says.

The CDC and WHO are watching the spread of several bird flu viruses that are known to infect people, including H5N1 and H7N2.

Related: Vet Catches Bird Flu From Cats

"Although the current risk to the public's health from A(H7N9) viruses is low, among the 12 novel influenza A viruses evaluated ... A(H7N9) viruses have the highest risk score and are characterized as posing moderate-high potential pandemic risk," the CDC team said in the report released Friday.

http://www.nbcnews.com/health/health-news/cdc-concerned-h7n9-bird-flu-s-sudden-spread-china-n728946

niman · March 4, 2017

Isolate detail

Isolate name:

A/Jiangsu/60450/2016

Isolate ID:

EPI_ISL_242886

Passage details/history:

E1

Type:

A / H7N9

Lineage:

Sample information

Collection date:

2016-12-19

Host

Human

Additional host information:

Zip code:

Patient status:

Last vaccinated:

In-vivo pathogenicity test:

Location:

China

Additional location information:

Jiangsu

Patient age:

23 Year(s)

Gender:

Male

Outbreak:

Treatment:

Specimen source:

Institute information

Originating lab:

Sample ID given by the sample provider:

Address:

Submitting lab:

WHO Chinese National Influenza Center

Sample ID given by the submitting laboratory:

Authors:

Wang,Dayan;
Zhou,Shumei;
Li,Xiyan;
Li,Xiaodan;
Zhang,Ye;
Bo,Hong;
Shu,Yuelong

Address:

WHO Chinese National Influenza Center
Virology Institute, Chinese CDC
 155 Changbai Road, Changping District,  
Beijing 102206
China

Publication

In vivo antiviral resistance

Antiviral resistance tested by experimental procedures

Adamantanes:

Unknown

Oseltamivir:

Unknown

Zanamivir:

Unknown

Peramivir:

Unknown

Other:

Unknown

Additional information

Antigenic characterization:

Note:

Sequence

segment	identifier	length	accession #
PB2	A_JIANGSU_60450_2016_DEC-PB2	2280	EPI887961
PB1	A_JIANGSU_60450_2016_DEC-PB1	2274	EPI887962
PA	A_JIANGSU_60450_2016_DEC-PA	2151	EPI887960
HA	A_JIANGSU_60450_2016_DEC-HA	1683	EPI887964
NP	A_JIANGSU_60450_2016_DEC-NP	1497	EPI887957
NA	A_JIANGSU_60450_2016_DEC-NA	1398	EPI887963
MP	A_JIANGSU_60450_2016_DEC-MP	982	EPI887959
NS	A_JIANGSU_60450_2016_DEC-NS	838	EPI887958

Submitter information

Submitter:

Yang, Lei

Submission Date:

2017-01-25

Last modifier:

Yang, Lei

Last modified:

2017-01-25

Address:

WHO Chinese National Influenza Center
Virology Institute, Chinese CDC
 155 Changbai Road, Changping District,  
Beijing 102206
China

niman · March 4, 2017

Isolate detail

Isolate name:

A/Jiangsu/60451/2016

Isolate ID:

EPI_ISL_242885

Passage details/history:

E1

Type:

A / H7N9

Lineage:

Sample information

Collection date:

2016-12-19

Host

Human

Additional host information:

Zip code:

Patient status:

Last vaccinated:

In-vivo pathogenicity test:

Location:

China

Additional location information:

Jiangsu

Patient age:

73 Year(s)

Gender:

Male

Outbreak:

Treatment:

Specimen source:

Institute information

Originating lab:

Sample ID given by the sample provider:

Address:

Submitting lab:

WHO Chinese National Influenza Center

Sample ID given by the submitting laboratory:

Authors:

Wang,Dayan;
Zhou,Shumei;
Li,Xiyan;
Li,Xiaodan;
Zhang,Ye;
Bo,Hong;
Shu,Yuelong

Address:

WHO Chinese National Influenza Center
Virology Institute, Chinese CDC
 155 Changbai Road, Changping District,  
Beijing 102206
China

Publication

In vivo antiviral resistance

Antiviral resistance tested by experimental procedures

Adamantanes:

Unknown

Oseltamivir:

Unknown

Zanamivir:

Unknown

Peramivir:

Unknown

Other:

Unknown

Additional information

Antigenic characterization:

Note:

Sequence

segment	identifier	length	accession #
PB2	A_JIANGSU_60451_2016_DEC-PB2	2280	EPI887953
PB1	A_JIANGSU_60451_2016_DEC-PB1	2274	EPI887954
PA	A_JIANGSU_60451_2016_DEC-PA	2151	EPI887952
HA	A_JIANGSU_60451_2016_DEC-HA	1683	EPI887956
NP	A_JIANGSU_60451_2016_DEC-NP	1497	EPI887949
NA	A_JIANGSU_60451_2016_DEC-NA	1398	EPI887955
MP	A_JIANGSU_60451_2016_DEC-MP	982	EPI887951
NS	A_JIANGSU_60451_2016_DEC-NS	838	EPI887950

Submitter information

Submitter:

Yang, Lei

Submission Date:

2017-01-25

Last modifier:

Yang, Lei

Last modified:

2017-01-25

Address:

WHO Chinese National Influenza Center
Virology Institute, Chinese CDC
 155 Changbai Road, Changping District,  
Beijing 102206
China

niman · March 4, 2017

Isolate detail

Isolate name:

A/Anhui/60936/2016

Isolate ID:

EPI_ISL_242884

Passage details/history:

E1

Type:

A / H7N9

Lineage:

Sample information

Collection date:

2016-12-16

Host

Human

Additional host information:

Zip code:

Patient status:

Last vaccinated:

In-vivo pathogenicity test:

Location:

China

Additional location information:

Anhui

Patient age:

49 Year(s)

Gender:

Male

Outbreak:

Treatment:

Specimen source:

Institute information

Originating lab:

Sample ID given by the sample provider:

Address:

Submitting lab:

WHO Chinese National Influenza Center

Sample ID given by the submitting laboratory:

Authors:

Wang,Dayan;
Zhou,Shumei;
Li,Xiyan;
Li,Xiaodan;
Zhang,Ye;
Bo,Hong;
Shu,Yuelong

Address:

WHO Chinese National Influenza Center
Virology Institute, Chinese CDC
 155 Changbai Road, Changping District,  
Beijing 102206
China

Publication

In vivo antiviral resistance

Antiviral resistance tested by experimental procedures

Adamantanes:

Unknown

Oseltamivir:

Unknown

Zanamivir:

Unknown

Peramivir:

Unknown

Other:

Unknown

Additional information

Antigenic characterization:

Note:

Sequence

segment	identifier	length	accession #
PB2	A_ANHUI_60936_2016_DEC-PB2	2280	EPI887945
PB1	A_ANHUI_60936_2016_DEC-PB1	2274	EPI887946
PA	A_ANHUI_60936_2016_DEC-PA	2151	EPI887944
HA	A_ANHUI_60936_2016_DEC-HA	1683	EPI887948
NP	A_ANHUI_60936_2016_DEC-NP	1497	EPI887941
NA	A_ANHUI_60936_2016_DEC-NA	1398	EPI887947
MP	A_ANHUI_60936_2016_DEC-MP	982	EPI887943
NS	A_ANHUI_60936_2016_DEC-NS	838	EPI887942

Submitter information

Submitter:

Yang, Lei

Submission Date:

2017-01-25

Last modifier:

Yang, Lei

Last modified:

2017-01-25

Address:

WHO Chinese National Influenza Center
Virology Institute, Chinese CDC
 155 Changbai Road, Changping District,  
Beijing 102206
China

niman · March 4, 2017

Isolate detail

Isolate name:

A/Jiangsu/60454/2016

Isolate ID:

EPI_ISL_242883

Passage details/history:

E1

Type:

A / H7N9

Lineage:

Sample information

Collection date:

2016-11-25

Host

Human

Additional host information:

Zip code:

Patient status:

Last vaccinated:

In-vivo pathogenicity test:

Location:

China

Additional location information:

Jiangsu

Patient age:

64 Year(s)

Gender:

Male

Outbreak:

Treatment:

Specimen source:

Institute information

Originating lab:

Sample ID given by the sample provider:

Address:

Submitting lab:

WHO Chinese National Influenza Center

Sample ID given by the submitting laboratory:

Authors:

Wang,Dayan;
Zhou,Shumei;
Li,Xiyan;
Li,Xiaodan;
Zhang,Ye;
Bo,Hong;
Shu,Yuelong

Address:

WHO Chinese National Influenza Center
Virology Institute, Chinese CDC
 155 Changbai Road, Changping District,  
Beijing 102206
China

Publication

In vivo antiviral resistance

Antiviral resistance tested by experimental procedures

Adamantanes:

Unknown

Oseltamivir:

Unknown

Zanamivir:

Unknown

Peramivir:

Unknown

Other:

Unknown

Additional information

Antigenic characterization:

Note:

Sequence

segment	identifier	length	accession #
PB2	A_JIANGSU_60454_2016_NOV-PB2	2280	EPI887937
PB1	A_JIANGSU_60454_2016_NOV-PB1	2274	EPI887938
PA	A_JIANGSU_60454_2016_NOV-PA	2151	EPI887936
HA	A_JIANGSU_60454_2016_NOV-HA	1683	EPI887940
NP	A_JIANGSU_60454_2016_NOV-NP	1497	EPI887933
NA	A_JIANGSU_60454_2016_NOV-NA	1398	EPI887939
MP	A_JIANGSU_60454_2016_NOV-MP	982	EPI887935
NS	A_JIANGSU_60454_2016_NOV-NS	838	EPI887934

Submitter information

Submitter:

Yang, Lei

Submission Date:

2017-01-25

Last modifier:

Yang, Lei

Last modified:

2017-01-25

Address:

WHO Chinese National Influenza Center
Virology Institute, Chinese CDC
 155 Changbai Road, Changping District,  
Beijing 102206
China

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