niman Posted January 8, 2020 Report Share Posted January 8, 2020 Media reports in China and US are suggesting that a novel coronavirus is associated with the "mystery" pneumonia cases being reported in Wuhan. Link to comment Share on other sites More sharing options...
niman Posted January 8, 2020 Author Report Share Posted January 8, 2020 (edited) Report post (IP: 73.214.85.79) Posted 1 hour ago Wuhan pneumonia epidemic-related market closed, animal viscera scattered on street corners 2020 at 18:26 on January 1st From the test results obtained so far, there is a very small possibility that cannot be ruled out, but it is really very inclined not to be SARS coronavirus. The homology is very low, with less than 4% gene coverage, making it impossible to judge. Need to test again. https://k.sina.com.cn/article_1315590387_4e6a50f301900p0k6.html?from=news&subch=onews Edited January 8, 2020 by niman Link to comment Share on other sites More sharing options...
niman Posted January 8, 2020 Author Report Share Posted January 8, 2020 New Virus Discovered by Chinese Scientists Investigating Pneumonia Outbreak Latest tally of people sickened in Wuhan is 59, with seven in a critical condition Public-health officials in Bangkok hand out disease-monitoring information after performing thermal scans on passengers arriving from Wuhan, China, on Wednesday. Photo: Lauren DeCicca/Getty Images By Natasha Khan Updated Jan. 8, 2020 8:04 am ET Save print Text HONG KONG—Chinese scientists investigating a mystery illness that has sickened dozens in central China have discovered a new strain of coronavirus, a development that will test the country’s upgraded capabilities for dealing with unfamiliar infectious diseases. The novel coronavirus was genetically sequenced from a sample from one patient and subsequently found in some of the others affected in the city of Wuhan, according to people familiar with the findings. Chinese authorities haven’t concluded that the strain is the underlying cause of sickness in all the patients who have been isolated in Wuhan since the infection first broke out in early December, the people said. There are many known coronaviruses—some can cause ailments like common colds in humans, while others don’t affect humans at all. Some—such as severe acute respiratory syndrome, or SARS, in 2003—have led to deadly outbreaks, lending urgency to efforts to contain the current situation. High Alert Some past coronavirus outbreaks, such as SARS and MERS, have had high death rates. Yet, there is no suggestion this new illness would cause such issues so far. SARS MERS* 8,098 2,468 Cases Deaths 774 851 Death rate 9.6% 34.5% When 2002-2003 2012- Where first reported China Saudi Arabia *As of September 2019 Sources: Centers for Disease Control and Prevention, World Health Organization The number of reported cases of viral pneumonia in Wuhan, the capital of Hubei province, was 59 on Sunday, rising from 27 on Dec. 31, according to Wuhan’s Municipal Health Commission, with seven people in a critical condition. No deaths have been reported. The disease afflicting patients in Wuhan hasn’t been transmitted from human to human, and health-care workers have remained uninfected, according to city health officials as of Jan. 5, suggesting that what is sickening them is for now less virulent than SARS. Those ill in Wuhan are believed to have become sick through exposure to animals linked to a live seafood and animal market. Health experts say one risk is that the disease could become a bigger threat as tens of millions of Chinese travel around the country during the Lunar New Year holidays that begin in just over two weeks. Health authorities in Singapore and Hong Kong, cities that have direct flights from Wuhan, have issued alerts and quarantined patients travelling from the region who show signs of fever or breathing difficulties. In Hong Kong on Tuesday, the government said it was taking precautions against a “severe respiratory disease associated with a novel infectious agent” that it is seeking to make a statutory notifiable infectious disease, meaning doctors would need to report any suspected cases, and patients evading quarantine could be fined or jailed. A visitor walked past a large photo depicting the 2003 SARS epidemic at an exhibition, ‘40 Years Through the Lens,’ at the National Museum of China, in Beijing, September 2018. Photo: wu hong/EPA/Shutterstock The Chinese Center for Disease Control and Prevention is expected to make an announcement of its findings in the coming days, a person familiar with the matter said. The CDC couldn’t be reached for comment late Tuesday. China was criticized for initially covering up SARS, which was first detected in late 2002 but was disclosed only after it began spreading widely, eventually killing 774 people globally, according to the World Health Organization. Beijing overhauled the nation’s disease control after reviews found that initial failures to contain and isolate patients with SARS allowed it to proliferate across densely populated Southern China. The Wuhan outbreak will test how much has changed. “We learned a bitter lesson in 2003, and we do not want that to happen again,” said Alex Lam, chairman of advocacy group Hong Kong Patients’ Voices. “China should immediately release their findings so doctors across the world can better know how to tackle this illness.” Hong Kong’s department of health, citing information from China’s National Health Commission, said the cause of the cluster of pneumonia cases detected in Wuhan was still under investigation, but other known respiratory pathogens had been ruled out. The main clinical symptoms of those affected by the Wuhan outbreak are fever—with a few patients having difficulty breathing—and invasive lesions of both lungs, which show up on chest radiographs, the WHO said Sunday. A mourner wearing a mask to ward off SARS under an umbrella during the funeral of a SARS doctor in Hong Kong in 2003. Photo: bobby yip/Reuters It is unclear what the underlying source of the disease is, though the reported link to a wholesale fish and live animal market could indicate an exposure link to animals, the WHO said. Bats, for example, are known “reservoirs” for coronaviruses, and have been found to transmit the disease to humans through a third vector such as a civet cat, as scientists found in the case of SARS. The pattern of the unexplained pneumonia cases linked to the market selling seafood and also live game strongly suggests that this is a novel microbe jumping from animal to human, said K.Y. Yuen, Chair Professor of Infectious Diseases at the University of Hong Kong’s Faculty of Medicine. Researchers have determined that a large proportion of new infectious diseases in humans are transmitted via animals. Such illnesses are referred to as zoonoses. Two newer human coronaviruses, MERS-CoV and SARS-CoV, have been known to cause severe illness and death, according to the U.S. Centers for Disease Control. The Wuhan strain is similar to bat coronaviruses that were a precursor to SARS, according to a person familiar with the new findings. Given the marked advances in hospital isolation facilities, infection-control training and laboratory diagnostic capabilities in the past two decades, it is unlikely that this outbreak will lead to a major 2003-like epidemic, Mr. Yuen said. In Wuhan, which has China’s first Biosafety Level 4 laboratory—a specialized research laboratory that deals with potentially deadly infectious agents like Ebola—the market at the center of investigations has been shut down since Jan 1. In Hong Kong, badly hit by the SARS virus, which claimed 299 lives locally in 2003, residents have donned surgical masks on the streets and public transport in recent days, despite no local cases of the Wuhan infection being confirmed. —Stephanie Yang contributed to this article. Write to Natasha Khan at [email protected] https://www.wsj.com/articles/new-virus-discovered-by-chinese-scientists-investigating-pneumonia-outbreak-11578485668?mod=searchresults&page=1&pos=2 Link to comment Share on other sites More sharing options...
niman Posted January 8, 2020 Author Report Share Posted January 8, 2020 Hayes Luk @hayesluk · Jan 5 5th Jan Wuhan official report 1. 59 cases, 7 of them are severe, no ones are killed by the pneumonia. 2. SARS and MERS are now ruled out, not yet for novel #coronavirus. 3. No obvious #h2h evidence. Link to comment Share on other sites More sharing options...
niman Posted January 8, 2020 Author Report Share Posted January 8, 2020 Wuhan Municipal Health and Health Commission's briefing on the current pneumonia epidemic situation in our city Issuing authority: Wuhan City health committee | Published: 2019-12-31 13:38:05 | Hits: 73 223 | Font Size: Tai Zhong Small Recently, some medical institutions found that many of the pneumonia cases received were related to South China Seafood City. After receiving the report, the Municipal Health and Health Commission immediately launched a case search and retrospective investigation related to South China Seafood City in the city's medical and health institutions. Twenty-seven cases have been found , of which 7 are in serious condition, and the remaining cases are stable and controllable. Two patients are expected to be discharged in the near future. The clinical manifestations of the cases were mainly fever, a few patients had difficulty breathing, and chest radiographs showed bilateral lung infiltrative lesions. At present, all cases have been isolated for treatment, follow-up investigations and medical observations of close contacts are ongoing, and hygiene investigations and environmental sanitation disposals for South China Seafood City are ongoing. Wuhan organized consultations with clinical medical, epidemiological, and virological experts from Tongji Hospital, Provincial CDC, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan Infectious Diseases Hospital, and Wuhan CDC. According to the analysis of epidemiological investigations and preliminary laboratory tests, the above cases are considered to be viral pneumonia. Investigations so far have not revealed any apparent human-to-human transmission or infection by medical staff. Detection of the pathogen and investigation of the cause of the infection are ongoing. Viral pneumonia is more common in winter and spring, and can be spread or outbreak. The clinical manifestations are fever, soreness, dyspnea in a small part, and lung infiltration. Viral pneumonia is related to the virulence of the virus, the route of infection, and the age and immune status of the host. Viruses that cause viral pneumonia are common with influenza viruses, others are parainfluenza virus, cytomegalovirus, adenovirus, rhinovirus, and coronavirus. Confirmation depends on pathogenic tests, including virus isolation, serological tests, and viral antigen and nucleic acid tests. The disease is preventable and controllable, and indoor air circulation can be prevented to prevent closed and airless public places and crowded places. Masks can be worn when going out. Symptomatic treatment is the main clinical practice, and bed rest is required. If you have the above symptoms, especially the persistent fever, you should go to the medical institution in time. December 31, 2019 http://wjw.wuhan.gov.cn/front/web/showDetail/2019123108989 Link to comment Share on other sites More sharing options...
niman Posted January 8, 2020 Author Report Share Posted January 8, 2020 Wuhan Municipal Health and Health Commission's Report on Unexplained Viral Pneumonia Issuing authority: Wuhan City health committee | Published: 2020-01-03 17:00:42 | Hits: 46388 | Font Size: Tai Zhong Small Since December 2019 , our committee has carried out surveillance of respiratory diseases and related diseases, and found cases of viral pneumonia of unknown cause. The clinical manifestations of the cases are mainly fever, a few patients have difficulty breathing, and chest radiographs show bilateral lung infiltrative lesions. As of 8:00 on January 3, 2020, a total of 44 patients with unexplained diagnosis of viral pneumonia were found, of which 11 were critically ill, and the remaining patients' overall vital signs were stable. At present, all cases are receiving isolation treatment in Wuhan medical institutions. 121 close contacts have been tracked and medical observations have been tracked. The follow-up of close contacts is still in progress. An epidemiological survey showed that some cases were operating households in Wuhan South China Seafood City. As of now, preliminary investigations have shown no clear evidence of human-to-human transmission and no medical staff infections. Pathogen identification (including nucleic acid detection and virus isolation and culture) and cause tracing are ongoing, and common respiratory diseases such as influenza, avian influenza, and adenovirus infection have been ruled out. After the outbreak, the State and Provincial Health and Health Commission attached great importance to it and sent working groups and expert teams to Wuhan to guide the local epidemic response and disposal work. Wuhan Municipal Health and Health Commission has conducted relevant case searches and retrospective investigations in medical institutions throughout the city, and has completed the environmental sanitation disposal of South China Seafood City, and further hygiene investigations are ongoing. January 3, 2020 http://wjw.wuhan.gov.cn/front/web/showDetail/2020010309017 Link to comment Share on other sites More sharing options...
niman Posted January 8, 2020 Author Report Share Posted January 8, 2020 Wuhan Municipal Health Committee's report on unexplained viral pneumonia Issuing authority: Wuhan City health committee | Published: 2020-01-05 20:33:24 | Hits: 76737 | Font Size: Tai Zhong Small Since December 31, 2019, our committee has carried out search and retrospective investigation of viral pneumonia cases of unknown cause in the city. As of 8:00 on January 5, 2020, a total of 59 patients with unexplained diagnosis of viral pneumonia were reported in our city, including 7 critically ill patients, and the remaining patients' overall vital signs were stable. At present, all patients are being isolated in medical institutions in Wuhan Treatment, no deaths. Among the 59 patients, the earliest onset of the case was December 12, 2019, and the latest onset was December 29; 163 close contacts have been followed up for medical observation, and the follow-up of close contacts is still in progress . An epidemiological survey showed that some patients were operating households in Wuhan South China Seafood City (South China Seafood Wholesale Market). As of now, preliminary investigations have shown no clear evidence of human-to-human transmission and no medical staff infections. Respiratory pathogens such as influenza, avian influenza, adenovirus, infectious atypical pneumonia ( SARS) and the Middle East Respiratory Syndrome (MERS) have been excluded . Pathogen identification and cause tracing are still underway. At present, with the support of the state and Hubei Province, Wuhan has adopted the following main prevention and control measures: First, it is to treat patients with all its strength. The second is to carry out isolation treatment for all cases. The third is to continue to conduct relevant case searches and retrospective investigations in medical institutions throughout the city. The fourth is to carry out close contact tracking seriously, implement medical observation on the close contacts that have been tracked according to regulations, and have not found any abnormal symptoms such as fever. Fifth, we will take measures to suspend the market for South China Seafood City, and carry out environmental sanitation and further hygiene investigations. Sixth, actively carry out epidemiological investigations. Seventh, cooperate with the state and province to carry out pathogen identification (including nucleic acid detection and virus isolation and culture) and trace the cause of the cause, and the prevention and control work is proceeding in an orderly manner. Experts advise that the city is currently in the season of high incidence of infectious diseases in winter and spring. Citizens should pay attention to maintaining indoor air circulation, avoiding closed and airless public places and crowded places, and wear masks if necessary. If you have fever, respiratory infection symptoms, especially persistent fever, go to a medical institution in time. http://wjw.wuhan.gov.cn/front/web/showDetail/2020010509020 Link to comment Share on other sites More sharing options...
niman Posted January 8, 2020 Author Report Share Posted January 8, 2020 Pneumonia of unknown cause – China Disease outbreak news 5 January 2020 On 31 December 2019, the WHO China Country Office was informed of cases of pneumonia of unknown etiology (unknown cause) detected in Wuhan City, Hubei Province of China. As of 3 January 2020, a total of 44 patients with pneumonia of unknown etiology have been reported to WHO by the national authorities in China. Of the 44 cases reported, 11 are severely ill, while the remaining 33 patients are in stable condition. According to media reports, the concerned market in Wuhan was closed on 1 January 2020 for environmental sanitation and disinfection. The causal agent has not yet been identified or confirmed. On 1 January 2020, WHO requested further information from national authorities to assess the risk. National authorities report that all patients are isolated and receiving treatment in Wuhan medical institutions. The clinical signs and symptoms are mainly fever, with a few patients having difficulty in breathing, and chest radiographs showing invasive lesions of both lungs. According to the authorities, some patients were operating dealers or vendors in the Huanan Seafood market. Based on the preliminary information from the Chinese investigation team, no evidence of significant human-to-human transmission and no health care worker infections have been reported. Public Health Response National authorities have reported the following response measures: One hundred and twenty-one close contacts have been identified and are under medical observation; The follow-up of close contacts is ongoing; Pathogen identification and the tracing of the cause are underway; Wuhan Municipal Health Commission carried out active case finding, and retrospective investigations have been completed; Environmental sanitation and further hygiene investigations are under way. WHO is closely monitoring the situation and is in close contact with national authorities in China. WHO risk assessment There is limited information to determine the overall risk of this reported cluster of pneumonia of unknown etiology. The reported link to a wholesale fish and live animal market could indicate an exposure link to animals. The symptoms reported among the patients are common to several respiratory diseases, and pneumonia is common in the winter season; however, the occurrence of 44 cases of pneumonia requiring hospitalization clustered in space and time should be handled prudently. Wuhan city, with a population of 19 million, is the capital city of Hubei province, with a population of 58 million people. WHO has requested further information on the laboratory tests performed and the differential diagnoses considered. WHO advice Based on information provided by national authorities, WHO’s recommendations on public health measures and surveillance of influenza and severe acute respiratory infections still apply. WHO does not recommend any specific measures for travellers. In case of symptoms suggestive of respiratory illness either during or after travel, travellers are encouraged to seek medical attention and share travel history with their healthcare provider. WHO advises against the application of any travel or trade restrictions on China based on the current information available on this event. https://www.who.int/csr/don/05-january-2020-pneumonia-of-unkown-cause-china/en/ Link to comment Share on other sites More sharing options...
niman Posted January 8, 2020 Author Report Share Posted January 8, 2020 (edited) Just in Time for Lunar New Year, Another SARS-like Epidemic Is Brewing in China Scores of people in Wuhan and Hong Kong have been sent to hospitals because of a mystery respiratory ailment—and true to form, China is trying to keep it quiet. BY LAURIE GARRETT | JANUARY 8, 2020, 12:56 PM Public health officials run thermal scans on passengers arriving from Wuhan, China, at Suvarnabhumi Airport in Bangkok on Jan 8. LAUREN DECICCA/GETTY IMAGES Here we go again. A mysterious outbreak sickens people in China, causing panic in Hong Kong, Singapore, and Taiwan as the world awaits real information from Beijing. We have been here many times before, from deadly influenza epidemics in the 1990s to SARS in 2003, with more flus since and recently even a cluster of pneumonic plague cases. This time around, the story begins with a mysterious respiratory outbreak on Dec. 12 in the central Chinese city of Wuhan. It sent at least 59 people to isolation wards in infectious diseases hospitals, where seven are now said to be in critical condition. As is typical, Beijing has kept mum about the outbreak, aside from insisting that the scientists—including non-Chinese—toiling to identify the culprit microorganism need to maintain secrecy and that there is no evidence that it can be spread from person to person. In fact, the government delayed notifying anybody about the pneumonia outbreak until Wuhan city officials acknowledged it two weeks after its apparent onset. In part because of the delay, the disease spread—there have been at least 16 cases so far in restive Hong Kong and one putative case in Singapore—and Beijing has threatened to jail individuals who convey further information about the disease on social media. The government of Chinese President Xi Jinping is doing itself no favors by handling outbreaks in such a brutal and secretive fashion. The government of Chinese President Xi Jinping is doing itself no favors by handling outbreaks in such a brutal and secretive fashion. Regardless of whatever legitimate scientific inquiry may now be underway, the lack of transparency and domestic repression of so-called rumormongers simply fuel international suspicions of a cover-up, perhaps of a larger-than-admitted epidemic. Most of the news media worldwide has compared the Wuhan outbreak to the 2003 SARS (severe acute respiratory syndrome) epidemic, which spread from mainland China to nearly 30 nations, sickening upwards of 8,000 people, killing 774, and sowing panic around the world. China would do well to remember the lessons of that outbreak—particularly the humiliation its leaders suffered from anger across Asia—and open the lid on daily information on the Wuhan pneumonia investigation. And it had better do so before Jan. 25, the Lunar New Year, when millions of Chinese pass through the nation’s high-speed train hub of Wuhan on their way to celebrate the holiday with relatives. As of this writing, it seems that the new outbreak started in, or around, a very large indoor fish market in the city of Wuhan, which has a population of more than 11 million and is located south of Beijing in Hubei province. Whatever the precise origin, most of the subsequent infections have been in Wuhan. Two of China’s major rivers—the Yangtze and Han—flow through the city, making it one of China’s oldest and most important centers of commerce. It is also a hub in China’s vast high-speed railway system, which carries millions of passengers daily. In other words, the latest outbreak has not struck some remote outpost, as has been the case with other epidemics, including Ebola in the Democratic Republic of the Congo, but has arisen in a central hub in a country that is, itself, at the center of international trade and travel. The Medical Administration of Wuhan Municipal Health Committee first raised the alarm on Dec. 30, when it posted a red alert on its website, declaring an “urgent notice on the treatment of pneumonia of unknown cause.” Local reporters who called the Health Committee hotline were merely told that there was a pneumonia outbreak of unknown cause involving 27 patients, most of whom were connected in some way to the South China Seafood Market. The patients exhibited respiratory distress, reduced white blood cell counts, and high fevers, and they failed to improve with antibiotic treatment. A viral cause was suspected. On New Year’s Eve, Hubei provincial authorities put out a report announcing that an official inquiry concurred that “27 cases of viral pneumonia have been found, all of which were diagnosed with viral pneumonia/pulmonary infection. Of the 27 cases, seven were critically ill, and the remaining cases were controllable. Two of them improved and were expected to be discharged soon.” That night, Hong Kong authorities began tightening security, acknowledging that three travelers who had been in Wuhan had ended up in hospitals in the territory suffering respiratory distress. One woman was being treated in Princess Margaret Hospital, which managed many of the 2003 SARS cases. Along with Hong Kong, Singapore and Taiwan also began conducting temperature screenings at airports and train stations, hoping to spot feverish pneumonia carriers before they could spread whatever the mysterious disease might be. Then, on New Year’s Day, alleged medical documents appeared on Chinese social media and Twitter purporting to show that the outbreak was, in fact, caused by the SARS virus, which is a member of the coronavirus family. But by Jan. 3, Chinese authorities said they had ruled out several types of pneumonia, as well as SARS, noting that the mystery agent was not a coronavirus and bore less than 4 percent genetic similarity with SARS. Concern about another SARS epidemic was ill-placed, authorities said, and they arrested eight individuals from Wuhan, who now face severe punishments for “publishing false information on the internet without verification.” https://foreignpolicy.com/2020/01/08/lunar-new-year-hong-kong-pnuemonia-sars-epidemic-wuhan/ Edited January 8, 2020 by niman Link to comment Share on other sites More sharing options...
niman Posted January 8, 2020 Author Report Share Posted January 8, 2020 Wuhan pneumonia epidemic-related market closed, animal viscera scattered on street corners 2020 at 18:26 on January 1st Since December 2019, 27 unexplained pneumonia patients have appeared in Wuhan, most of which are business operators in South China Seafood City, Jianghan District, Wuhan. On January 1st, the South China Seafood Market posted a closing announcement, saying that environmental sanitation will be carried out. ↑ Closed Notice The announcement of the rest of the market was jointly issued by the Wuhan Jianghan District Market Supervision and Administration Bureau and the Jianghan District Health and Health Bureau. The announcement showed that "according to the provisions of the State Council's" Regulations on Public Health Emergencies "and other regulations and regulations The situation of pneumonia was reported. After research, it was decided that the South China Seafood Wholesale Market should be closed for environmental sanitation. We would like to actively cooperate with the merchants. The market opening time will be notified separately. "The payment time is January 1. ↑ Wuhan South China Seafood Wholesale Market The reporter called a merchant selling dry goods and seasonings in the market, saying that he had to “close” when he received a phone call from another merchant at 6 am. “I came late in the morning, unlike other seafood vendors.” The merchant said that if I did n’t open the door before the holiday, and I had to go back to my hometown Xinyang in advance to celebrate the New Year. The day before, the reporter visited the South China Seafood Market and found that there were abandoned rabbit heads and animal offal in the market. Many merchants confirmed that rabbits, pheasants and snakes were sold in the market. However, the reporter did not see the slaughter at the scene, and the surrounding merchants said that it had closed. Reporters visited South China seafood market Animal offal scattered on the street "Public patients with unexplained pneumonia in the South China Seafood Market in Wuhan have been aroused." The reporter found that a netizen named @ 万 谦 宠爱 _Yuki posted on Weibo that the South China seafood market had pheasants, snakes, marmots and other animals slaughtered and sold. The netizen said that he had been to the South China Seafood Market. Signboards like that are hanging brightly ... " ↑ Abandoned animal carcasses and internal organs at the end of Sixth Street, West District On the afternoon of December 31, the reporter visited the South China Seafood Market in Jianghan District, Wuhan City, and found that there were abandoned rabbit heads and animal offal scattered on the corner of Sixth Street in the western part of the market. The owner of a nearby stall said that there are several vendors selling game on Sixth Street, such as pheasants, snakes, and many other varieties. Iron cage. The stall owner was very alert to reporters asking if there were any game sales. At the entrance of the Western District, the reporter asked several stall sellers and shopkeepers selling dry goods where they could buy game, saying "Go inside." ↑ The "Selling Game" shop is located at Sixth Street, West Market, and is currently closed At around 4:30 pm, the reporter found in the market that several staff members of the Wuhan Centers for Disease Control and Prevention were wearing plain clothes, holding a list, and taking pictures of the merchant's signs separately. The staff refused to answer questions from reporters about whether they are investigating patient booths. Reporters found at least 15 people's names and phone numbers on the list from the staff. The reporter then asked a stall owner at the entrance of the Western District, a person named Li Mouhuan, who said that he was a "sell beast (game)" merchant in the market. ↑ The staff of CDC are investigating The reporter then verified the above statement with the relevant staff at the South China Seafood Market Management Office. A staff member said "no comment" and said that the relevant government departments had organized a meeting for them, and all the information issued by the relevant departments shall prevail. The investigation found that most of the pneumonia cases were from South China Seafood City operators. At present, related virus typing, isolation treatment, public opinion control, and terminal disinfection are underway. At present, all cases have been isolated for treatment, follow-up investigations and medical observations of close contacts are ongoing, and hygiene investigations and environmental sanitation disposals for South China Seafood City are ongoing. According to a virus research expert at the Medical Department of Wuhan University, in general, it is difficult to imagine pneumonia virus coming out of the seafood market. The most infectious diseases in the seafood market are hepatitis A and Vibrio parahaemolyticus infections, which are imported from the mouth. The expert said that even if there is, it is also a human reason, and has a smaller relationship with the seafood there. From the test results obtained so far, there is a very small possibility that cannot be ruled out, but it is really very inclined not to be SARS coronavirus. The homology is very low, with less than 4% gene coverage, making it impossible to judge. Need to test again. The expert said that in general, pneumonia pathogens are very rare in the pure seafood market. Generally, pneumonia can be caused. For example, SARS pathogens in 2003 "are more in wild animals." The expert reminded: during the high flu season, you should avoid going to crowded places, especially children and the elderly. At home, pay attention to ventilation and strengthen exercise. Recently, Class A and Class B have spread, and many primary and secondary schools have suspended classes. Influenza greatly reduces immunity and is also prone to co-infection and cause pneumonia. https://k.sina.com.cn/article_1315590387_4e6a50f301900p0k6.html?from=news&subch=onews Link to comment Share on other sites More sharing options...
niman Posted January 8, 2020 Author Report Share Posted January 8, 2020 Published Date: 2020-01-08 10:30:07 Subject: PRO/AH/EDR> Undiagnosed pneumonia - China (HU) (05): novel coronavirus identified Archive Number: 20200108.6877694 UNDIAGNOSED PNEUMONIA - CHINA (HUBEI) (05): NOVEL CORONAVIRUS IDENTIFIED ************************************************************************ A ProMED-mail posthttp://www.promedmail.org ProMED-mail is a program of the International Society for Infectious Diseaseshttp://www.isid.org Date: Wed 8 Jan 2019 Source: Wall Street Journalhttps://www.wsj.com/articles/new-virus-discovered-by-chinese-scientists-investigating-pneumonia-outbreak-11578485668 New Virus Discovered by Chinese Scientists Investigating Pneumonia Outbreak Latest tally of people sickened in Wuhan is 59, with 7 in a critical condition ---------------------------------------------- Chinese scientists investigating a mystery illness that has sickened dozens in central China have discovered a new strain of coronavirus, a development that will test the country's upgraded capabilities for dealing with unfamiliar infectious diseases. The novel coronavirus was genetically sequenced from a sample from 1 patient and subsequently found in some of the others affected in the city of Wuhan, according to people familiar with the findings. Chinese authorities haven't concluded that the strain is the underlying cause of sickness in all the patients who have been isolated in Wuhan since the infection 1st broke out in early December [2019], the people said. There are many known coronaviruses -- some can cause ailments like common colds in humans, while others don't affect humans at all. Some - such as severe acute respiratory syndrome, or SARS, in 2003 - have led to deadly outbreaks, lending urgency to efforts to contain the current situation. High Alert Some past coronavirus outbreaks, such as SARS and MERS, have had high death rates. Yet, there is no suggestion this new illness would cause such issues so far. SARS / MERS* ----------------------- Cases: 8098 / 2468 Deaths: 774 / 851 Death rate: 9.6% / 34.5% When: 2002-2003 / 2012- Where first reported: China / Saudi Arabia *As of September 2019 Sources: Centers for Disease Control and Prevention, World Health Organization The number of reported cases of viral pneumonia in Wuhan, the capital of Hubei province, was 59 on Sunday, rising from 27 on [31 Dec 2019], according to Wuhan's Municipal Health Commission, with 7 people in a critical condition. No deaths have been reported. The disease afflicting patients in Wuhan hasn't been transmitted from human to human, and health-care workers have remained uninfected, according to city health officials as of [5 Jan 2020], suggesting that what is sickening them is for now less virulent than SARS. Those ill in Wuhan are believed to have become sick through exposure to animals linked to a live seafood and animal market. Health experts say one risk is that the disease could become a bigger threat as tens of millions of Chinese travel around the country during the Lunar New Year holidays that begin in just over 2 weeks. Health authorities in Singapore and Hong Kong, cities that have direct flights from Wuhan, have issued alerts and quarantined patients travelling from the region who show signs of fever or breathing difficulties. In Hong Kong on Tuesday [7 Jan 2020], the government said it was taking precautions against a "severe respiratory disease associated with a novel infectious agent" that it is seeking to make a statutory notifiable infectious disease, meaning doctors would need to report any suspected cases, and patients evading quarantine could be fined or jailed. The Chinese Center for Disease Control and Prevention is expected to make an announcement of its findings in the coming days, a person familiar with the matter said. The CDC couldn't be reached for comment late Tuesday [7 Jan 2020]. China was criticized for initially covering up SARS, which was 1st detected in late 2002 but was disclosed only after it began spreading widely, eventually killing 774 people globally, according to the World Health Organization. Beijing overhauled the nation's disease control after reviews found that initial failures to contain and isolate patients with SARS allowed it to proliferate across densely populated Southern China. The Wuhan outbreak will test how much has changed. "We learned a bitter lesson in 2003, and we do not want that to happen again," said Alex Lam, chairman of advocacy group Hong Kong Patients' Voices. "China should immediately release their findings so doctors across the world can better know how to tackle this illness." Hong Kong's department of health, citing information from China's National Health Commission, said the cause of the cluster of pneumonia cases detected in Wuhan was still under investigation, but other known respiratory pathogens had been ruled out. The main clinical symptoms of those affected by the Wuhan outbreak are fever - with a few patients having difficulty breathing - and invasive lesions of both lungs, which show up on chest radiographs, the WHO said Sunday [5 Jan 2020]. It is unclear what the underlying source of the disease is, though the reported link to a wholesale fish and live animal market could indicate an exposure link to animals, the WHO said. Bats, for example, are known "reservoirs" for coronaviruses, and have been found to transmit the disease to humans through a third vector such as a civet cat, as scientists found in the case of SARS. The pattern of the unexplained pneumonia cases linked to the market selling seafood and also live game strongly suggests that this is a novel microbe jumping from animal to human, said K.Y. Yuen, Chair Professor of Infectious Diseases at the University of Hong Kong's Faculty of Medicine. Researchers have determined that a large proportion of new infectious diseases in humans are transmitted via animals. Such illnesses are referred to as zoonoses. 2 newer human coronaviruses, MERS-CoV and SARS-CoV, have been known to cause severe illness and death, according to the U.S. Centers for Disease Control. The Wuhan strain is similar to bat coronaviruses that were a precursor to SARS, according to a person familiar with the new findings. Given the marked advances in hospital isolation facilities, infection-control training and laboratory diagnostic capabilities in the past two decades, it is unlikely that this outbreak will lead to a major 2003-like epidemic, Mr. Yuen said. In Wuhan, which has China's 1st Biosafety Level 4 laboratory - a specialized research laboratory that deals with potentially deadly infectious agents like Ebola - the market at the center of investigations has been shut down since [1 Jan 2020]. In Hong Kong, badly hit by the SARS virus, which claimed 299 lives locally in 2003, residents have donned surgical masks on the streets and public transport in recent days, despite no local cases of the Wuhan infection being confirmed. [Byline: Natasha Khan] -- Communicated by: ProMED-mail Rapporteur Kunihiko Iizuka and Ryan McGinnis <[email protected]> [This is not a surprising finding for all of the reasons stated in previous posts (and speculated there as well). The well known coronaviruses are those that are responsible for the SARS (severe acute respiratory syndrome) and MERS (Middle Eastern Respiratory Syndrome) outbreaks in 2002-2003 and 2012 to the present respectively (see insert table in media report above. Coronaviruses belong to the subfamily _Coronavirinae_ in the family _Coronaviridae_, in the order _Nidovirales_. Coronaviruses are enveloped viruses with a positive-sense single-stranded RNA genome and with a nucleocapsid of composed of helical symmetry. There are other human coronaviruses that have been associated with mild upper respiratory symptoms (commonly referred to as the "common cold"). More information on this novel coronavirus from knowledgeable sources would be greatly appreciated. A map of China showing locations of major cities in China can be found at https://www.chinadiscovery.com/china-maps/city-maps.html. HealthMap/ProMED-mail map of Hubei Province, China: http://healthmap.org/promed/p/340. - Mod.MPP] See Also Undiagnosed pneumonia - China (HU) (04): Hong Kong surveillance 20200106.6874277 Undiagnosed pneumonia - China (HU) (03): updates, SARS, MERS ruled out, WHO, RFI 20200105.6872267 Undiagnosed pneumonia - China (02): (HU) updates, other country responses, RFI 20200103.6869668 Undiagnosed pneumonia - China (01): (HU) wildlife sales, market closed, RFI 20200102.6866757 2019 ---- Undiagnosed pneumonia - China (HU), RFI 20191230.6864153 .................................................lm/mpp/mlhttps://promedmail.org/promed-post/?id=20200108.6877694 Link to comment Share on other sites More sharing options...
niman Posted January 8, 2020 Author Report Share Posted January 8, 2020 WHO says mysterious illness in China likely being caused by new virus By HELEN BRANSWELL @HelenBranswell JANUARY 8, 2020 Health officials hand out disease monitoring information after performing thermal scans on passengers arriving in Bangkok from Wuhan, China.LAUREN DECICCA/GETTY IMAGES The World Health Organization confirmed on Wednesday that Chinese authorities believe a new coronavirus — from the family that produced SARS and MERS — may be the cause of mysterious pneumonia cases in the city of Wuhan. The Chinese government has not yet publicly stated that a coronavirus is the cause of the illness, which has infected at least 59 people. But the Wall Street Journal reported that was the case earlier Wednesday, citing unnamed sources. The WHO statement said that the virus can cause severe illness in some patients and does not “transmit readily” between people. Earlier statements from the Wuhan Municipal Health Authority have said there has been no person-to-person spread — a claim disease experts say is impossible to make at this stage in the outbreak. “Coronaviruses are a large family of viruses that range from the common cold to SARS. Some cause less-severe disease, some more severe. Some transmit easily from person to person, while others don’t,” the WHO said. The outbreak has been linked to a large seafood market which also sells live exotic animals. The market was closed on Jan. 1. This story will be updated. https://www.statnews.com/2020/01/08/who-says-mysterious-illness-in-china-likely-being-caused-by-new-virus/?utm_content=buffer5874a&utm_medium=social&utm_source=twitter&utm_campaign=twitter_organic Link to comment Share on other sites More sharing options...
niman Posted January 8, 2020 Author Report Share Posted January 8, 2020 WHO says mysterious illness in China likely being caused by new virus By HELEN BRANSWELL @HelenBranswell JANUARY 8, 2020 Health officials hand out disease monitoring information after performing thermal scans on passengers arriving in Bangkok from Wuhan, China.LAUREN DECICCA/GETTY IMAGES The World Health Organization confirmed on Wednesday that Chinese authorities believe a new coronavirus — from the family that produced SARS and MERS — may be the cause of mysterious pneumonia cases in the city of Wuhan. The Chinese government has not yet publicly stated that a coronavirus is the cause of the illness, which has infected at least 59 people. But the Wall Street Journal reported that was the case earlier Wednesday, citing unnamed sources. “Coronaviruses are a large family of viruses that range from the common cold to SARS. Some cause less-severe disease, some more severe. Some transmit easily from person to person, while others don’t,” the WHO statement said. The virus can cause severe illness in some patients, the agency said, adding that it does not “transmit readily” between people. Earlier statements from the Wuhan Municipal Health Authority said there has been no person-to-person spread — a claim disease experts say is impossible to make at this stage in the exploration of a new disease. “I don’t know how you know that at all,” said Matthew Frieman, a coronavirus expert at the University of Maryland School of Medicine. He noted the number of cases reported makes it seem unlikely that animal-to-human transmission is the only way this virus spread. The WHO said that as authorities home in on the cause — and develop better detection tools — the number of cases associated with this outbreak may rise. The fact that a coronavirus may be responsible will come as no surprise to the infectious diseases experts who have been watching the situation unfold. The type of illness and the fact that it is emerging in China — where a number of SARS-like and other coronaviruses have been isolated from bats — has pointed in that direction. Experts said it will now be important for China to share more information, including enough of a genetic sequence so that health facilities outside of China know what to look for when faced with a pneumonia case with a recent travel history to Wuhan. As it currently stands, Hong Kong is isolating any such cases until they can be tested for influenza, rhinoviruses, and other viruses that cause colds and flu. Given it is flu season in the Northern Hemisphere, telling countries to be on the look out for travelers with fevers and cold-like symptoms casts a very broad net. “It really behooves them to at least provide enough information to allow the global community to be ready to do testing,” said Ralph Baric, a coronavirus expert at the University of North Caroline. “Otherwise you’re just doing screening for fever — in the middle of respiratory disease season? Financial nightmare.” It will also be critical to figure out how the virus transmitted to people. The outbreak has been linked to a large seafood market that also sells live exotic animals for consumption. The market was closed and decontaminated on Jan. 1. Baric said investigations will be underway to identify which species — singular or plural — was infected in the market. “Understanding the reservoir is critical for eliminating that whole aspect of animal-to-human jump,” Frieman said. Identifying the reservoir of the virus will also require tracing the animals suspected of being infected back to their suppliers so that it can be determined whether other markets might also have received infected animals. During the 2003 SARS outbreak — in which more than 8,000 people were infected and nearly 800 died — the source of the virus was traced to palm civets that are eaten as a delicacy in parts of China. The Chinese government ordered a mass culling of the animals as part of its effort to stop the outbreak. News of the pneumonia cases first emerged on Dec. 30, when the local health authority told hospitals to be on the lookout for cases. The next day Chinese authorities informed the WHO that they were dealing with what looked like an outbreak caused by an unknown virus. In its most recent update, the Wuhan Municipal Health Authority said there had been 59 cases, seven of which were in critical condition. The statement said the first known case began showing signs of illness on Dec. 12 and the last case of illness onset was Dec. 29. About the Author Helen Branswell Senior Writer, Infectious Disease Helen Branswell covers issues broadly related to infectious diseases, including outbreaks, preparedness, research, and vaccine development. [email protected] @HelenBranswell https://www.statnews.com/2020/01/08/who-says-mysterious-illness-in-china-likely-being-caused-by-new-virus/?utm_content=buffer5874a&utm_medium=social&utm_source=twitter&utm_campaign=twitter_organic Link to comment Share on other sites More sharing options...
Admin Posted January 8, 2020 Report Share Posted January 8, 2020 Outbreak of Pneumonia of Unknown Etiology (PUE) in Wuhan, China Distributed via the CDC Health Alert Network January 8, 2020, 1615 ET (04:15 PM ET) CDCHAN-00424 Summary The Centers for Disease Control and Prevention (CDC) is closely monitoring a reported cluster of pneumonia of unknown etiology (PUE) with possible epidemiologic links to a large wholesale fish and live animal market in Wuhan City, Hubei Province, China. An outbreak investigation by local officials is ongoing in China; the World Health Organization (WHO) is the lead international public health agency. Currently, there are no known U.S. cases nor have cases been reported in countries other than China. CDC has established an Incident Management Structure to optimize domestic and international coordination if additional public health actions are required. This HAN Advisory informs state and local health departments and health care providers about this outbreak and requests that health care providers ask patients with severe respiratory disease about travel history to Wuhan City. Wuhan City is a major transportation hub about 700 miles south of Beijing with a population of more than 11 million people. Background According to a report from the Wuhan Municipal Health Commission, as of January 5, 2020, the national authorities in China have reported 59 patients with PUE to WHO. The patients had symptom onset dates from December 12 through December 29, 2019. Patients involved in the cluster reportedly have had fever, dyspnea, and bilateral lung infiltrates on chest radiograph. Of the 59 cases, seven are critically ill, and the remaining patients are in stable condition. No deaths have been reported and no health care providers have been reported to be ill. The Wuhan Municipal Health Commission has not reported human-to-human transmission. Reports indicate that some of the patients were vendors at the Wuhan South China Seafood City (South China Seafood Wholesale Market) where, in addition to seafood, chickens, bats, marmots, and other wild animals are sold, suggesting a possible zoonotic origin to the outbreak. The market has been closed for cleaning and disinfection. Local authorities have reported negative laboratory test results for seasonal influenza, avian influenza, adenovirus, severe acute respiratory syndrome-associated coronavirus (SARS-CoV), and Middle East respiratory syndrome coronavirus (MERS-CoV) among patients associated with this cluster. Additional laboratory testing is ongoing to determine the source of the outbreak. Health authorities are monitoring more than 150 contacts of patients for illness. CDC has issued a level 1 travel notice (“practice usual precautions”) for this destination. (https://wwwnc.cdc.gov/travel/notices/watch/pneumonia-china). On January 5, 2020, WHO posted an update on this situation, including an early risk assessment, which is available at: https://www.who.int/csr/don/05-january-2020-pneumonia-of-unkown-cause-china/en/external icon. Recommendations for Health Care Providers Providers should consider pneumonia related to the cluster for patients with severe respiratory symptoms who traveled to Wuhan since December 1, 2019 and had onset of illness within two weeks of returning, and who do not have another known diagnosis that would explain their illness. Providers should notify infection control personnel and local and state health departments immediately if any patients meet these criteria. State health departments should notify CDC after identifying a case under investigation by calling CDC’s Emergency Operations Center at (770) 488-7100. Multiple respiratory tract specimens should be collected from persons with infections suspected to be associated with this cluster, including nasopharyngeal, nasal, and throat swabs. Patients with severe respiratory disease also should have lower respiratory tract specimens collected, if possible. Consider saving urine, stool, serum, and respiratory pathology specimens if available. Although the etiology and transmissibility have yet to be determined, and to date, no human-to-human transmission has been reported and no health care providers have been reported ill, CDC currently recommends a cautious approach to symptomatic patients with a history of travel to Wuhan City. Such patients should be asked to wear a surgical mask as soon as they are identified and be evaluated in a private room with the door closed. Personnel entering the room to evaluate the patient should use contact precautions and wear an N95 disposable facepiece respirator. For patients admitted for inpatient care, contact and airborne isolation precautions, in addition to standard precautions, are recommended until further information becomes available. For additional information see: https://www.cdc.gov/infectioncontrol/guidelines/isolation/index.html. This guidance will be updated as more information becomes available. For More Information 1-800-CDC-INFOhttps://www.cdc.gov/cdc-info/index.html CDC’s Emergency Operations Center: 770-488-7100 https://emergency.cdc.gov/han/han00424.asp Link to comment Share on other sites More sharing options...
niman Posted January 9, 2020 Author Report Share Posted January 9, 2020 (edited) People's Daily, China @PDChina · 43m Experts say the previously unidentified pneumonia in Wuhan, central China's Hubei Province, which has had 59 confirmed cases, is believed to be a new type of coronavirus. Follow People's Daily, China @PDChina The largest newspaper in China Beijing, Chinapeople.cnJoined May 2011 4,594 Following 7M Followers Edited January 9, 2020 by niman Link to comment Share on other sites More sharing options...
Admin Posted January 9, 2020 Report Share Posted January 9, 2020 Wuhan unidentified virus pneumonia outbreak pathogen identified as new coronavirus 01-09 08:14Author: Shi Yingchun Source: CCTV News152 comments Abstract: [Preliminary identification of unexplained viral pneumonia pathogen in Wuhan as a new coronavirus] On the progress of the pathogenic identification of unexplained viral pneumonia epidemic in Wuhan, the reporter learned today from the expert group for preliminary assessment of pathogen detection results that as of 2020 At 21:00 on January 7th, a new type of coronavirus was detected in the laboratory, and the whole genome sequence of the virus was obtained. A total of 15 cases of positive results of the new type of coronavirus were detected by the nucleic acid detection method. The virus was isolated from a positive patient sample. Virus, showing typical coronavirus morphology under electron microscope. (CCTV News) Regarding the progress of the pathogenic identification of unexplained viral pneumonia epidemic in Wuhan, the reporter learned from the expert group of preliminary assessment of pathogenic test results today that as of 21:00 on January 7, 2020, a new type of coronavirus was detected in the laboratory and obtained The whole genome sequence of the virus was detected by nucleic acid detection method in a total of 15 cases of new coronavirus positive results. The virus was isolated from a positive patient sample and showed typical coronavirus appearance under electron microscope. The expert group believes that the pathogen of this unexplained case of viral pneumonia was initially identified as a new type of coronavirus. Tissue laboratories use genomic sequencing, nucleic acid detection, virus isolation, and other methods to etiologically detect samples from patients with alveolar lavage fluid, throat swabs, and blood. The expert group stated that the identification of the cause of an epidemic usually requires the following: (1) Suspicious pathogens must be found in patients, and pathogenic nucleic acids can be detected in clinical samples of patients; (2) The pathogen can be successfully isolated from the clinical sample of the patient; (3) Infecting host animals with isolated pathogens can cause the same disease symptoms. The patient's serum antibody titer during the recovery period increased four-fold, which can help identify the pathogen. Finding the nucleic acid, genomic and antibody evidence of the pathogen from the patient can be done in a short time. Scientific research, such as pathogen isolation and pathogenicity identification, can take weeks. The development of specific drugs and vaccines against a new pathogen may take years to complete. The expert group believes that the pathogen of this unexplained case of viral pneumonia is initially determined as a new type of coronavirus. The next step is to conduct expert research and judgement in combination with pathogenic research, epidemiological investigation and clinical manifestations. Coronaviruses are a group of pathogens that cause respiratory and intestinal diseases. There are many regularly arranged protrusions on the surface of this type of virus particle, and the entire virus particle is like an emperor's crown, hence the name "coronavirus". In addition to humans, coronaviruses can infect many mammals such as pigs, cattle, cats, dogs, marten, camels, bats, mice, hedgehogs, and various birds. So far, there are six known human coronaviruses. Four of these coronaviruses are more common in the population and are less pathogenic, generally causing only minor respiratory symptoms similar to the common cold. The other two coronaviruses—Severe Acute Respiratory Syndrome Coronavirus and Middle East Respiratory Syndrome Coronavirus, also known as SARS Coronavirus and MERS Coronavirus, can cause severe respiratory diseases. The new coronavirus that caused the epidemic is different from the human coronaviruses that have been discovered, and further understanding of the virus requires further scientific research. https://emwap.eastmoney.com/news/info/detail/202001091351309088 Link to comment Share on other sites More sharing options...
Admin Posted January 9, 2020 Report Share Posted January 9, 2020 Experts claim that the new coronavirus is unidentified in Wuhan 2020-01-09 09:45:59 Source: Xinhuanet Xinhua News Agency, Beijing, January 9 (Reporter Qu Ting) A few days ago, on the issue of the pathogenic identification of unexplained viral pneumonia epidemic in Wuhan, the reporter interviewed Xu Jianguo, the leader of the preliminary assessment of pathogenic test results and a member of the Chinese Academy of Engineering. He said that the expert group believed that the pathogen of this unexplained case of viral pneumonia was initially determined to be a new coronavirus. Question 1: At present, what progress has been made in the pathogenic identification of unexplained viral pneumonia in Wuhan? Xu Jianguo: As of 21:00 on January 7, 2020, a new coronavirus was detected in the laboratory, and the entire genome sequence of the virus was obtained. A total of 15 positive results of the new coronavirus were detected by nucleic acid detection methods. From 1 positive patient The virus was isolated from the samples and showed a typical coronavirus appearance under an electron microscope. The expert group believes that the pathogen of this unexplained case of viral pneumonia was initially identified as a new type of coronavirus. Question 2: How is the pathogen identification carried out? Xu Jianguo: The tissue laboratory used genomic sequencing, nucleic acid detection, virus isolation and other methods to perform pathogenic tests on patients' alveolar lavage fluid, throat swabs, blood and other samples. Question 3: What procedures are needed to identify the pathogen? Xu Jianguo: To confirm the cause of an epidemic disease, usually the following points must be met: (1) Suspicious pathogens must be found in patients, and pathogenic nucleic acids can be detected in clinical samples of patients; (2) From clinical samples of patients The pathogen can be successfully isolated; (3) The isolated pathogen can cause the same disease symptoms after infecting the host animal. The patient's serum antibody titer during the recovery period increased four-fold, which can help identify the pathogen. Finding the nucleic acid, genomic and antibody evidence of the pathogen from the patient can be done in a short time. Scientific research, such as pathogen isolation and pathogenicity identification, can take weeks. The development of specific drugs and vaccines against a new pathogen may take years to complete. Question 4: What is the next step? Xu Jianguo: The expert group believes that the pathogen of this unexplained case of viral pneumonia is initially determined as a new type of coronavirus. The next step is to conduct expert research and judgement in combination with etiology research, epidemiological investigation and clinical manifestations. Question 5: What is a coronavirus? Xu Jianguo: Coronavirus is a type of pathogen that mainly causes respiratory and intestinal diseases. There are many regularly arranged protrusions on the surface of this type of virus particle, and the entire virus particle is like an emperor's crown, hence the name "coronavirus". In addition to humans, coronaviruses can infect many mammals such as pigs, cattle, cats, dogs, marten, camels, bats, mice, hedgehogs, and various birds. So far, there are six known human coronaviruses. Four of these coronaviruses are more common in the population and are less pathogenic, generally causing only minor respiratory symptoms similar to the common cold. The other two coronaviruses—Severe Acute Respiratory Syndrome Coronavirus and Middle East Respiratory Syndrome Coronavirus, also known as SARS Coronavirus and MERS Coronavirus, can cause severe respiratory diseases. The new coronavirus that caused the epidemic is different from the human coronaviruses that have been discovered, and further understanding of the virus requires further scientific research. http://www.xinhuanet.com/2020-01/09/c_1125438971.htm Link to comment Share on other sites More sharing options...
niman Posted January 9, 2020 Author Report Share Posted January 9, 2020 The Wuhan strain is similar to bat coronaviruses that were a precursor to SARS, according to a person familiar with the new findings. Given the marked advances in hospital isolation facilities, infection-control training and laboratory diagnostic capabilities in the past two decades, it is unlikely that this outbreak will lead to a major 2003-like epidemic, Mr. Yuen said.In Wuhan, which has China's 1st Biosafety Level 4 laboratory - a specialized research laboratory that deals with potentially deadly infectious agents like Ebola - the market at the center of investigations has been shut down since [1 Jan 2020]. https://promedmail.org/promed-post/?id=20200108.6877694 Link to comment Share on other sites More sharing options...
niman Posted January 9, 2020 Author Report Share Posted January 9, 2020 China confirms new coronavirus as it investigates mysterious Wuhan illness A new strain from the family that caused Sars is identified in 15 patients South China Morning Post January 09, 2020 SHARETWEETFLIPBOARDEMAIL c60548da-3284-11ea-9400-58350050ee52imagehires104801.jpg The Wuhan Huanan Seafood Wholesale Market is closed and under guard after being linked to the mystery illness late last month. Photo: Simon Song Chinese scientists investigating a mystery illness that has infected dozens in the central city of Wuhan have said it is a new strain of coronavirus from the same family that caused the 2002-03 Sars epidemic. Laboratory tests have found a new type of coronavirus and the whole genome sequence of the new virus has been obtained, state broadcaster China Central Television (CCTV) reported on Thursday, citing a task force of experts. Virus checks conducted on all passengers arriving via Wuhan trains Fifteen patients had tested positive for the new coronavirus, the report stated. It said the virus had been isolated from one of the 15 patients and showed “typical coronavirus morphology” under electron microscope observation. “The pathogen of these unexplained cases of viral pneumonia was initially identified as a new type of coronavirus,” the report quoted the expert group as saying. There have been 59 reported cases of the mysterious virus in Wuhan since late December, some of them connected to a seafood market in which wild animals had been sold. The market has since been closed. Retrospective study identified that the first case had been identified on December 12 and the latest on December 29. No deaths have been reported and eight patients, no longer showing pneumonia symptoms, had been discharged from hospital by Wednesday. The Wuhan health authority has said that no human-to-human transmission has so far been detected. 59 people found with mysterious illness in Wuhan Coronaviruses can infect mammals such as pigs, cattle, cats, dogs, camels, bats and mice, as well as humans. Of the six previously known human coronaviruses, four were common and caused only minor respiratory symptoms similar to those of a cold. The other two were serious respiratory diseases: the Severe Acute Respiratory Syndrome (Sars) coronavirus that killed more than 700 people worldwide after originating in China, and the Middle East Respiratory Syndrome coronavirus that had caused 449 deaths by 2015. https://yp.scmp.com/news/china/article/115246/china-confirms-new-coronavirus-it-investigates-mysterious-wuhan-illness Link to comment Share on other sites More sharing options...
niman Posted January 9, 2020 Author Report Share Posted January 9, 2020 China’s Mystery Pneumonia Cases Are Linked to Novel Coronavirus By Kristen V Brown January 8, 2020, 5:59 PM EST Updated on January 8, 2020, 8:20 PM EST Further research is needed to identify pathogen, CCTV says Eight patients in Wuhan have been discharged from hospital Public health officials run thermal scans on passengers arriving from Wuhan, China at Suvarnabumi Airport in Bangkok, Thailand on Jan 8. Photographer: Lauren DeCicca/Getty Images A mysterious pneumonia outbreak that has sickened dozens in central China is linked to a previously unidentified coronavirus, China Central Television said. Further research is needed on the virus, which is different to the coronavirus that causes Severe Acute Respiratory Syndrome, or SARS, CCTV said, citing scientists’ early findings. The World Health Organization said earlier Thursday a novel virus may be the cause of the outbreak in Wuhan. ADVERTISING Scientist have speculated for days that a novel coronavirus might have caused the Wuhan outbreak as officials there ruled out other coronaviruses -- including SARS and MERS-CoV -- as well as influenza, avian influenza and adenovirus. Public health officials run thermal scans on passengers arriving from Wuhan, China at Suvarnabumi Airport in Bangkok, Thailand on Jan 8. Photographer: Lauren DeCicca/Getty Images The WHO said that more comprehensive information is needed to positively identify the pathogen. The virus doesn’t transmit readily between people, the WHO said, citing Chinese authorities. How China’s Mystery Illness Is and Isn’t Like SARS: QuickTake Dozens of people have been hospitalized in Wuhan since the first patient developed symptoms Dec. 12. Some patients worked at a seafood market where birds, snakes and rabbit organs were reportedly sold. There have been no reports of fatalities or health-care workers becoming infected, and CCTV said eight patients have been discharged from the hospital. The illness also doesn’t appear to be spreading outside Wuhan. While regions including Hong Kong and Singapore have reported illnesses from travelers who had been to Wuhan, none so far has shown a link to the pneumonia cluster. Coronaviruses are a large family of viruses that range from the common cold to SARS, the WHO said. Some cause less-severe disease, some more severe. Some transmit easily from person to person, while others don’t. “Disease X” -- a term used to denote a previously unknown disease -- is “one of the key health security risks in today’s world, and a priority for global monitoring,” said James M. Wilson, a pediatrician who has helped monitor health security threats for 25 years. Such diseases are often reported very late, after severe cases emerge, Wilson said. But since SARS, there has been a dramatic increase in access to sophisticated diagnostic testing, allowing for the early identification of viruses. In the Wuhan case, the Chinese may be dealing with a virus that is not as lethal as SARS, which killed almost 800 people about 17 years ago, or is in early stages of discovery before deaths have occurred, he said. — With assistance by Jason Gale, and Dong Lyu https://www.bloomberg.com/news/articles/2020-01-08/china-s-mystery-pneumonia-illness-may-be-linked-to-new-virus?utm_campaign=socialflow-organic&cmpid=socialflow-twitter-business&utm_medium=social&utm_content=business&utm_source=twitter Link to comment Share on other sites More sharing options...
niman Posted January 9, 2020 Author Report Share Posted January 9, 2020 1 hr interview TONIGHT at midnight ET on Wuhon Novel Coronavirus sequence in same class as SARS CoV Link to comment Share on other sites More sharing options...
niman Posted January 9, 2020 Author Report Share Posted January 9, 2020 Correction 1 hr interview TONIGHT at 11 ET (NOW) on Wuhon Novel Coronavirus sequence in same class as SARS CoV Link to comment Share on other sites More sharing options...
niman Posted January 9, 2020 Author Report Share Posted January 9, 2020 1 minute ago, niman said: Correction 1 hr interview TONIGHT at 11 ET (NOW) on Wuhon Novel Coronavirus sequence in same class as SARS CoV https://www.renseradio.com/listenlive.php Link to comment Share on other sites More sharing options...
Admin Posted January 9, 2020 Report Share Posted January 9, 2020 Infectious disease expert Lu Hongzhou: no need to panic about the emergence of new coronavirus January 9, 2020 10:31 Look at the news KNEWS Original title: Infectious disease expert Lu Hongzhou: New coronavirus appears without panic In the past few days, the epidemic of unexplained viral pneumonia in Wuhan has caught the attention of the whole society. After eight patients with unexplained viral pneumonia were cured and discharged from Wuhan, the good news came again on the morning of January 9 that the "true murder" of unexplained viral pneumonia in Wuhan had been found. According to authoritative media reports, the expert group believes that the pathogen of this unexplained case of viral pneumonia was initially determined to be a new type of coronavirus. Professor Lu Hongzhou, an infectious disease expert and secretary of the Party Committee of Shanghai Public Health Clinical Center affiliated to Fudan University, said that coronavirus infections are very common around the world, and the public need not panic. Coronaviruses are a group of pathogens that cause respiratory and intestinal diseases. There are many regularly arranged protrusions on the surface of this type of virus particle, and the entire virus particle is like an emperor's crown, hence the name "coronavirus". So far, there are six known human coronaviruses. Among them, HCoV-229E, HCoV-NL63, HCoV-OC43, and HCoV-HKU1 are mostly self-limiting after infection with the four coronaviruses. They are mainly caused by "common cold" symptoms such as nasal congestion, runny nose, and sneezing. Neurological complications. However, both SARS-CoV and MERS-CoV coronaviruses are highly pathogenic and can cause fatal pneumonia. The two coronaviruses have similar clinical features. They can have obvious systemic symptoms such as fever, headache, myalgia, and fatigue. In some cases, they can also start with gastrointestinal symptoms such as diarrhea, which can quickly progress to shortness of breath and progressive breathing. The manifestation of failure can also be accompanied by damage to other organ functions such as acute kidney injury. After coronavirus infection, treatment is mainly symptomatic and supportive. Combining with the new coronavirus appearing in Wuhan this time, Lu Hongzhou believes that it is necessary to strengthen the understanding of pneumonia of unknown origin, while satisfying: fever (underarm temperature ≥38 ° C); imaging characteristics of pneumonia; reduced or normal white blood cell count in early stages, or lymph Cell sorting counts were reduced; after a standardized antibacterial drug treatment for 3-5 days did not significantly improve the disease or showed progressive worsening of the four clinical features, it is necessary to consider unexplained pneumonia. If unexplained pneumonia is found, for a certain degree of time-space congregation of respiratory infectious diseases, the hospital should strengthen clinical triage to quickly find and report cases of unexplained pneumonia, and isolate and observe and treat suspected or confirmed cases; medical treatment Institutions and public health places should be adequately ventilated and clean, and a sustainable infection prevention and control infrastructure should be established; when diagnosing and treating related cases that may or may be diagnosed, or when conducting clinical testing and scientific research on related specimens, appropriate levels should be adopted Protective measures to further reduce the risk of transmission. Once patients with unexplained pneumonia have symptoms of severe respiratory infections, Lu Hongzhou reminded to adopt symptomatic supportive treatment such as ventilator mechanical ventilation and external membrane oxygenation (ECMO) according to the condition. When taking the drug, Lu Hongzhou suggested that broad-spectrum antiviral drugs still have no exact effect on coronavirus, and neuraminidase inhibitor oseltamivir is effective against influenza, but has no effect on coronavirus. In addition, in order to prevent viral pneumonia, it is necessary to enhance the awareness of health and health, to strengthen exercise, work regularly, and improve their immunity. Even if the weather is cold, you should pay attention to ventilation in your room and office. Ventilation can reduce the amount of virus in the air and thus reduce infection. Family or office colleagues are sick during the epidemic season. Others should pay attention to isolation to reduce the chance of infection. Viral pneumonia In the flu season, try to get to crowded places as little as possible; after going home by public transportation such as subways and buses, change your coat, wash your hands, and wash your nose. Lu Hongzhou suggested that the entire population is generally susceptible to influenza, and drug prevention cannot replace vaccination. Influenza vaccination is the most effective way to prevent influenza virus infection and its serious complications. http://news.sina.com.cn/c/2020-01-09/doc-iihnzahk2978652.shtml Link to comment Share on other sites More sharing options...
Admin Posted January 9, 2020 Report Share Posted January 9, 2020 Wuhan unexplained pneumonia epidemic will spread to other regions? Official response 2020-01-09 11:51:32 Source: China Network RTHK reporter: Regarding pneumonia of unknown cause in Wuhan, which has been determined to be a new type of coronavirus, what will each department do during the Spring Festival Transport to avoid the spread of immunity to other mainland cities and other countries? Thank you. Wanxiang East: As of now, none of the passengers mentioned by civil aviation have found the situation of pneumonia patients you mentioned. But we will keep a close watch and strengthen our links with the health sector. In addition, the planes of all transportation airlines in China are equipped with emergency medical kits, health and epidemic prevention kits, and the medical emergency response equipment at the airport is also very complete, so it can ensure effective ground-to-air connection for medical emergencies. In the event of a sudden illness while flying, airlines and airports can initiate emergency measures in time to ensure that passengers can be treated accordingly. Thank you! Li Wenxin: The railway department has paid close attention to the relevant situation. At present, the railway station cars have not received relevant epidemic reports. We will pay close attention to the prevention and control of transportation in accordance with national regulations, resolutely prevent the spread of the epidemic through railway stations, and do our best to maintain the health and safety of passengers. Thank you. Wang Yang: During the Spring Festival, there will be a large number of people gathering, and infectious diseases are easy to occur. The emergence of the epidemic may cause everyone to worry about traveling during the Spring Festival, especially in areas where people are concentrated and concentrated. Arrangement and deployment will focus on the disinfection monitoring and protection measures in areas with a large number of passenger trips, including transportation hubs, passenger stations, and cargo hub factories and stations. Winter is also a season of frequent flu. I would like to remind everyone to take personal protective measures to ensure that they can go home healthily and safely. Thank you. http://news.163.com/20/0109/11/F2ER7TQU0001899O.html Link to comment Share on other sites More sharing options...
Recommended Posts
Please sign in to comment
You will be able to leave a comment after signing in
Sign In Now