Molecular mechanism for antibody-dependent enhancement of coronavirus entry

[khs]

Antibody-dependent enhancement (ADE) occurs when antibodies facilitate viral entry into host cells and enhance viral infection in these cells (1, 2). ADE has been observed for a variety of viruses, most notably in flaviviruses (e.g., dengue virus) (3-6).

Peer reviewed paper:

https://www.docdroid.net/uVOql5p/jvi02015-19full.pdf

So it is potentially far worse the second time you get it, which makes it an extremely worrying virus considering it's potential r0 value.

Edited February 20, 2020 by khs

[Jonathan Fillion]

Approved but did not review the paper, don't have enough time maybe @niman can comment about accuracy of the paper.