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Molecular mechanism for antibody-dependent enhancement of coronavirus entry


khs

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Antibody-dependent enhancement (ADE) occurs when antibodies facilitate viral entry into host cells and enhance viral infection in these cells (1, 2). ADE has been observed for a variety of viruses, most notably in flaviviruses (e.g., dengue virus) (3-6).

Peer reviewed paper:

https://www.docdroid.net/uVOql5p/jvi02015-19full.pdf

So it is potentially far worse the second time you get it, which makes it an extremely worrying virus considering it's potential r0 value.

Edited by khs
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