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Partial 2015 Zika Seqs Chiapas Mexico Match Washington DC Patient B


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Posted (edited)

InDRE released two partial Zika sequences from 46M in Chiapas,Mexico collected Nov 30, 2015 which exactly matches sequence from fetal brain collected from Washington DC traveler (FB-GWUH/2016), infected while on vacation (Nov 2015) that included travel to Mexico and Guatemala.

Edited by niman
Posted
LOCUS       KU985087                 755 bp    RNA     linear   VRL 28-MAR-2016
DEFINITION  Zika virus isolate MEX/InDRE/Zika-2/2015 nonstructural protein 5
            gene, partial cds.
ACCESSION   KU985087
VERSION     KU985087.1  GI:1011619245
KEYWORDS    .
SOURCE      Zika virus
  ORGANISM  Zika virus
            Viruses; ssRNA viruses; ssRNA positive-strand viruses, no DNA
            stage; Flaviviridae; Flavivirus.
REFERENCE   1  (bases 1 to 755)
  AUTHORS   Diaz-Quinonez,J.A., Vazquez-Pichardo,M., Nunez-Leon,A.,
            Torres-Rodriguez,M.D.L.L., Escobar-Escamilla,N.,
            Wong-Arambula,C.E., Torres-Longoria,B., Lopez-Martinez,I.,
            Ruiz-Matus,C., Kuri-Morales,P.A. and Ramirez-Gonzalez,J.E.
  TITLE     Molecular characterization of Zika virus in Mexico
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 755)
  AUTHORS   Vazquez-Pichardo,M., Nunez-Leon,A., Torres-Rodriguez,M.L.,
            Rosales-Jimenez,C., Torres-Olmos,Y.A., Perez-Meza,R.,
            Aparicio-Antonio,A.M., Herrera-Bautista,R.M., Wong-Arambula,C.E.,
            Rodriguez-Maldonado,A.P., Del Mazo-Lopez,J.C.,
            Serrano-Gutierrez,S., Escobar-Escamilla,N., Torres-Longoria,B.,
            Gomez-Bustamante,A., Lopez-Martinez,I., Ramirez-Gonzalez,J.E. and
            Diaz-Quinonez,J.A.
  TITLE     Direct Submission
  JOURNAL   Submitted (28-MAR-2016) Biologia Molecular y Validacion de
            Tecnicas, Instituto de Diagnostico y Referencia Epidemiologicos
            (InDRE), Francisco de P. Miranda 177 Col. Lomas de Plateros,
            Mexico, DF 01480, Mexico
COMMENT     ##Assembly-Data-START##
            Sequencing Technology :: Sanger dideoxy sequencing
            ##Assembly-Data-END##
FEATURES             Location/Qualifiers
     source          1..755
                     /organism="Zika virus"
                     /mol_type="genomic RNA"
                     /isolate="MEX/InDRE/Zika-2/2015"
                     /isolation_source="Serum"
                     /host="Homo sapiens; 46 years old; male"
                     /db_xref="taxon:64320"
                     /country="Mexico: Chiapas"
                     /collection_date="30-Nov-2015"
     CDS             <1..>755
                     /codon_start=1
                     /product="nonstructural protein 5"
                     /protein_id="AMR96778.1"
                     /db_xref="GI:1011619246"
                     /translation="EALGFLNEDHWMGRENSGGGVEGLGLQRLGYVLEEMSCIPGGRM
                     YADDTAGWDTRISRFDLENEALITNQMEKGHRALALAIIKYTYQNKVVKVLRPAEKGK
                     TVMDIISRQDQRGSGQVVTYALNTFTNLVVQLIRNMEAEEVLEMQDLWLLRRSEKVTN
                     WLQSNGWDRLKRMAVSGDDCVVKPIDDRFAHALRFLNDMGKVRKDTQEWKPSTGWDNW
                     EEVPFCSHHFNKLHLKDGRSIVVPCRHQDELIGR"
ORIGIN      
        1 gaagcccttg gattcttgaa cgaggatcac tggatgggga gagagaactc aggaggtggt
       61 gttgaagggc tgggattaca aagactcgga tatgtcctag aagagatgag ttgcatacca
      121 ggaggaagga tgtatgcaga tgacactgct ggctgggaca cccgcatcag caggtttgat
      181 ctggagaatg aagctctaat caccaaccaa atggagaaag ggcacagggc cttggcattg
      241 gccataatca agtacacata ccaaaacaaa gtggtaaagg tccttagacc agctgaaaaa
      301 gggaaaacag ttatggacat tatttcgaga caagaccaaa gggggagcgg acaagttgtc
      361 acttacgctc ttaacacatt taccaaccta gtggtgcaac tcattcggaa tatggaggct
      421 gaggaagttc tagagatgca agacttgtgg ctgctgcgga ggtcagagaa agtgaccaac
      481 tggttgcaga gcaacggatg ggataggctc aaacgaatgg cagtcagtgg agatgattgc
      541 gttgtgaagc caattgatga taggtttgca catgccctca ggttcttgaa tgatatggga
      601 aaagttagga aggacacaca agagtggaaa ccctcaactg gatgggacaa ctgggaagaa
      661 gttccgtttt gctcccacca cttcaacaag ctccatctca aggacgggag gtccattgtg
      721 gttccctgcc gccaccaaga tgaactgatt ggccg
Posted
Sequences producing significant alignments:

Select:AllNone Selected:0

Sequences producing significant alignments:
Select for downloading or viewing reportsDescriptionMax scoreTotal scoreQuery coverE valueIdentAccession
13621362100%0.0100%KU985087.1
13621362100%0.0100%KU870645.1
13571357100%0.099%KU497555.1
13571357100%0.099%KU647676.1
13571357100%0.099%KU501217.1
13571357100%0.099%KU501216.1
13531353100%0.099%KU991811.1
13531353100%0.099%KU926310.1
13531353100%0.099%KU926309.1
13531353100%0.099%KU729217.2
13531353100%0.099%KU820897.1
13531353100%0.099%KU509998.1
13531353100%0.099%KU321639.1
13531353100%0.099%KM078936.1
13531353100%0.099%KJ776791.1
13501350100%0.099%KM078961.1
13481348100%0.099%KU940228.1
13481348100%0.099%KU940224.1
13481348100%0.099%KU922960.1
13481348100%0.099%KU922923.1
13481348100%0.099%KU853013.1
13481348100%0.099%KU853012.1
13481348100%0.099%KU707826.1
13481348100%0.099%KU527068.1
13481348100%0.099%KU501215.1
13481348100%0.099%KU365780.1
13481348100%0.099%KU365779.1
13481348100%0.099%KU365777.1
13481348100%0.099%KM078930.1
13461346100%0.099%KM078971.1
13461346100%0.099%KM078970.1
13461346100%0.099%KM078933.1
13441344100%0.099%KU955590.1
13441344100%0.099%KU820898.1
13441344100%0.099%KU740184.2
13441344100%0.099%KU729218.1
13441344100%0.099%KU761564.1
13441344100%0.099%KU365778.1
13441344100%0.099%KU312312.1
13441344100%0.099%KM078929.1
1341134198%0.099%KU556802.1
13301330100%0.099%KU955589.1
13301330100%0.099%KU866423.1
13301330100%0.099%KU820899.2
13301330100%0.099%KU744693.1
13301330100%0.099%KF993678.1
1328132898%0.099%KJ873160.1
13261326100%0.099%KU681081.3
13261326100%0.099%KU179098.1
13031303100%0.098%KU955593.1
13031303100%0.098%JN860885.1
12991299100%0.098%EU545988.1
12811281100%0.098%KU681082.3
1249124992%0.099%KJ873161.1
1240124091%0.099%KU232300.1
1231123190%0.099%KU232290.1
1229122991%0.099%KU232297.1
1220122089%0.099%KU232294.1
1218121890%0.099%KU232292.1
1214121489%0.099%KU232298.1
1211121189%0.099%KU232296.1
1211121189%0.099%KU232293.1
1205120588%0.099%KU232295.1
1195119588%0.099%KU232288.1
1191119187%0.099%KU232289.1
1187118787%0.099%KU232299.1
1186118688%0.099%KU232291.1
11641164100%0.094%HQ234499.1
1047104778%0.099%KM851039.1
1016101678%0.098%KM851038.1
969969100%0.088%KF268949.1
966966100%0.088%KU955594.1
966966100%0.088%KU720415.1
966966100%0.088%LC002520.1
966966100%0.088%HQ234498.1
966966100%0.088%AY632535.2
966966100%0.088%AF013415.1
960960100%0.088%DQ859059.1
957957100%0.088%KF383121.1
957957100%0.088%KF383119.1
948948100%0.088%KU955595.1
948948100%0.088%KU955592.1
948948100%0.088%KU955591.1
946946100%0.088%KF268950.1
946946100%0.088%KF268948.1
939939100%0.088%KF383116.1
933933100%0.087%KF383118.1
930930100%0.087%HQ234501.1
930930100%0.087%HQ234500.1
915915100%0.087%KF383117.1
901901100%0.087%KF383115.1
88888891%0.088%KF383103.1
88888891%0.088%KF383086.1
85685691%0.087%KF383104.1
85285291%0.087%KF383085.1
84784791%0.087%KF383106.1
84384391%0.087%KF383114.1
84384391%0.087%KF383107.1
84384391%0.087%KF383088.1
83883891%0.087%KF383087.1
82582591%0.086%KF383089.1
82082091%0.086%KF383101.1
82082091%0.086%KF383097.1
81681691%0.086%KF383099.1
81081091%0.086%KF383098.1
78978991%0.085%KF383084.1
78078091%0.085%KF383113.1
762762100%0.082%KF383120.1
64164191%6e-18081%KF383092.1
63963991%2e-17980%KF383093.1
63663691%3e-17880%KF383095.1
63063091%1e-17680%KF383091.1
61861845%7e-173100%KU867812.1
33172353%2e-8699%KU940227.1
Posted
LOCUS       KU985088                 360 bp    RNA     linear   VRL 28-MAR-2016
DEFINITION  Zika virus isolate MEX/InDRE/Zika-2/2015 envelope protein gene,
            partial cds.
ACCESSION   KU985088
VERSION     KU985088.1  GI:1011619266
KEYWORDS    .
SOURCE      Zika virus
  ORGANISM  Zika virus
            Viruses; ssRNA viruses; ssRNA positive-strand viruses, no DNA
            stage; Flaviviridae; Flavivirus.
REFERENCE   1  (bases 1 to 360)
  AUTHORS   Diaz-Quinonez,J.A., Vazquez-Pichardo,M., Nunez-Leon,A.,
            Torres-Rodriguez,M.D.L.L., Escobar-Escamilla,N.,
            Wong-Arambula,C.E., Torres-Longoria,B., Lopez-Martinez,I.,
            Ruiz-Matus,C., Kuri-Morales,P.A. and Ramirez-Gonzalez,J.E.
  TITLE     Molecular characterization of Zika virus in Mexico
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 360)
  AUTHORS   Vazquez-Pichardo,M., Nunez-Leon,A., Torres-Rodriguez,M.L.,
            Rosales-Jimenez,C., Torres-Olmos,Y.A., Perez-Meza,R.,
            Aparicio-Antonio,A.M., Herrera-Bautista,R.M., Wong-Arambula,C.E.,
            Rodriguez-Maldonado,A.P., Del Mazo-Lopez,J.C.,
            Serrano-Gutierrez,S., Escobar-Escamilla,N., Torres-Longoria,B.,
            Gomez-Bustamante,A., Lopez-Martinez,I., Ramirez-Gonzalez,J.E. and
            Diaz-Quinonez,J.A.
  TITLE     Direct Submission
  JOURNAL   Submitted (28-MAR-2016) Biologia Molecular y Validacion de
            Tecnicas, Instituto de Diagnostico y Referencia Epidemiologicos
            (InDRE), Francisco de P. Miranda 177 Col. Lomas de Plateros,
            Mexico, DF 01480, Mexico
COMMENT     ##Assembly-Data-START##
            Sequencing Technology :: Sanger dideoxy sequencing
            ##Assembly-Data-END##
FEATURES             Location/Qualifiers
     source          1..360
                     /organism="Zika virus"
                     /mol_type="genomic RNA"
                     /isolate="MEX/InDRE/Zika-2/2015"
                     /isolation_source="Serum"
                     /host="Homo sapiens; 46 years old; male"
                     /db_xref="taxon:64320"
                     /country="Mexico: Chiapas"
                     /collection_date="30-Nov-2015"
     CDS             <1..>360
                     /codon_start=2
                     /product="envelope protein"
                     /protein_id="AMR96779.1"
                     /db_xref="GI:1011619267"
                     /translation="RCPTQGEAYLDKQSDTQYVCKRTLVDRGWGNGCGLFGKGSLVTC
                     AKFACSKKMTGKSIQPENLEYRIMLSVHGSQHSGMIVNDTGHETDENRAKVEITPNSP
                     RAEATLGGFGSLGLDCEP"
ORIGIN      
        1 ccgctgccca acacaaggtg aagcctacct tgacaagcaa tcagacactc aatatgtctg
       61 caaaagaacg ttagtggaca gaggctgggg aaatggatgt ggactttttg gcaaagggag
      121 cctggtgaca tgcgctaagt ttgcatgctc caagaaaatg accgggaaga gcatccagcc
      181 agagaatctg gagtaccgga taatgctgtc agttcatggc tcccagcaca gtgggatgat
      241 cgttaatgac acaggacatg aaactgatga gaatagagcg aaggttgaga taacgcccaa
      301 ttcaccaaga gccgaagcca ccctgggggg ttttggaagc ctaggacttg attgtgaacc
Posted
Sequences producing significant alignments:

Select:AllNone Selected:0

Sequences producing significant alignments:
Select for downloading or viewing reportsDescriptionMax scoreTotal scoreQuery coverE valueIdentAccession
650650100%0.0100%KU991811.1
650650100%0.0100%KU985088.1
650650100%0.0100%KU940228.1
650650100%0.0100%KU940224.1
650650100%0.0100%KU955589.1
650650100%0.0100%KU870645.1
650650100%0.0100%KU926309.1
650650100%0.0100%KU866423.1
650650100%0.0100%KU820899.2
650650100%0.0100%KU729217.2
650650100%0.0100%KU729218.1
650650100%0.0100%KU681081.3
650650100%0.0100%KU527068.1
650650100%0.0100%KU501217.1
650650100%0.0100%KU501216.1
650650100%0.0100%KJ634273.1
650650100%0.0100%KJ776791.1
645645100%0.099%KU955590.1
645645100%0.099%KU926310.1
645645100%0.099%KU922960.1
645645100%0.099%KU922923.1
645645100%0.099%KU853013.1
645645100%0.099%KU853012.1
645645100%0.099%KU497555.1
645645100%0.099%KU646828.1
645645100%0.099%KU646827.1
645645100%0.099%KU647676.1
645645100%0.099%KU509998.1
645645100%0.099%KU365778.1
645645100%0.099%KU312315.1
645645100%0.099%KU312314.1
645645100%0.099%KU321639.1
641641100%3e-18099%KU820898.1
641641100%3e-18099%KU740184.2
641641100%3e-18099%KU820897.1
641641100%3e-18099%KU761564.1
641641100%3e-18099%KU707826.1
641641100%3e-18099%KU501215.1
641641100%3e-18099%KU365780.1
641641100%3e-18099%KU365779.1
641641100%3e-18099%KU365777.1
641641100%3e-18099%KU312313.1
641641100%3e-18099%KU312312.1
641641100%3e-18099%EU545988.1
636636100%1e-17899%KU955593.1
636636100%1e-17899%KU681082.3
636636100%1e-17899%KU744693.1
636636100%1e-17899%JN860885.1
632632100%1e-17799%KF993678.1

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