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Confirmed Microcephaly Cases In Brazil Increase To 1046


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MICROCEPHALY: study shows that Q1 may be at higher risk for pregnant women

    Data are from research conducted by the Ministry of Health and the US CDC in Paraiba. The new release are 4,046 cases microcephaly research, 1,046 confirmed and 1,814 discarded

    The case-control study in Paraíba shows preliminarily that mothers who had the Zika virus in the first trimester of pregnancy were more likely to have children with microcephaly. The Ministry of Health, in partnership with the Government of Paraiba and Center for Disease Control and Prevention of Diseases (CDC) of the United States, continues with the analysis of blood samples collected from the mothers and babies paraibanos. Only after this phase, the final results will be announced. The initial result of the study, presented in João Pessoa (PB), also found no association of microcephaly with the exhibition of products such as insecticides, for example.

    "It's part of this study to investigate people who were not affected by microcephaly. Only after processing the collected blood samples, comparing cases and controls, can we estimate more clearly the risk of being affected by the disease and Zika's relationship with microcephaly, "said the aide Surveillance Secretariat of Health the Ministry of Health, Eduardo Hage, highlighting the commitment of the teams in the field phase of the research. "The study gave an agile, ethical and effective manner. The teams have taken important steps in the search for answers to the problem that concerns the world, "the Secretary of Health Surveillance, Ministry of Health, Antonio Nardi.

    The research, which began on 22 February, featured the work of eight teams - composed by the institutions involved - who investigated the proportion of infants born with microcephaly associated with Zika, and the risk of virus infection in 56 municipalities state. Overall, respondents were 165 cases of mothers who had babies with microcephaly and 446 control (mothers and babies in the same area without microcephaly). Among the babies, 52% are female and 48% male, in the age group 0-7 months.

    NEW RELEASE  - In Brazil, 4,046 suspected cases of microcephaly are under investigation, according to a new report released on Tuesday (5) by the Ministry of Health since the beginning of the investigation, in October 2015, by 2. April - were 6,906 notifications in 1,307 municipalities of all units of the federation. Cases already completed, 1,814 have been discarded and 1,046 were confirmed to microcephaly and other nervous system disorders, suggestive of congenital infection.

    Of these, 170 have had laboratory confirmation to the Zika virus. In these cases, it performed specific laboratory test for the Zika virus. However, the Ministry of Health points out that this figure does not represent adequately the total number of cases related to the virus. That is, the folder considers that there was infection Zika most of the mothers who had babies with a final diagnosis of microcephaly.

    Until April 2, there were 227 deaths (fetal or neonatal) microcephaly suspects and / or alteration of the central nervous system after birth or during pregnancy (miscarriage or stillbirth). Of these, 51 were confirmed to microcephaly and / or alteration of the central nervous system. Other 148 are still under investigation and 28 were discarded.

    It should be noted that the Ministry of Health is investigating all cases of microcephaly and other disorders of the central nervous system, informed by the states, and the possible relationship with the Zika virus and other congenital infections. Microcephaly may be caused by, various infectious agents beyond Zika as Syphilis, Toxoplasmosis, Other Infectious Agents, Rubella, Cytomegalovirus and Herpes Viral.

    The Ministry of Health advises pregnant women to adopt measures to reduce the presence of Aedes aegypti, with the elimination of breeding sites, and protect themselves from mosquito exposure, keeping doors and closed or screened windows, wear pants and long-sleeved shirt and use repellents allowed for pregnant women.

    RESEARCH - Another study by a research group on the Zika epidemic (MERG) pointed out that 100 mothers of children with microcephaly interviews in the state of Pernambuco, 59 noted the presence of rash (rash) during pregnancy, common symptom in people infected by Zika virus. The research was published in a journal of the Center for Communicable Disease Control and Prevention (CDC), the United States.

    This group, specialist Oswaldo Cruz Pernambuco Foundation - Aggeu Magalhães Research Center (Fiocruz / CPqAM), the Pan American Health Organization / World Health Organization (PAHO / WHO), the Ministry of Health, the Institute of Medicine integral professor Fernando Figueira (IMIP), the Federal University of Pernambuco Federal University of Rio Grande do Sul, the Secretary of State of Pernambuco Health, the Federal Border South University, the University of Pernambuco, the Evaluation Institute of Technology Health and the London School of Hygiene & Tropical Medicine.

    Distribution of reported cases of microcephaly by UF until April 2, 2016

    Regions and Federative UnitsMicrocephaly cases and / or malformations suggestive of congenital infectionTotal accumulated 1of reported cases from 2015 to 2016
    researchconfirmed 2.3discarded 4
    Brazil4,0461,0461,8146906
    Alagoas7252131255
    Bahia663194134991
    Ceará24776114437
    Maranhão1356634235
    Paraíba386103364853
    Pernambuco1,0533034901,846
    Piauí317049150
    large northern river2908335408
    Sergipe1573117205
    Northeast3,0349781,3685,380
    Holy Spirit91418113
    Minas Gerais28two4676
    Rio de Janeiro2972162380
    Sao Paulo162 * 5094256
    Southeast region57827220825
    Acre301two33
    Amapátwo305
    Amazon111113
    For231024
    Rondônia53412
    Roraima * 6160016
    Tocantins116017133
    North region203924236
    Federal district143237
    Goiás82930121
    Mato Grosso1131471198
    Mato Grosso do Sul5two1118
    Midwest region20129144374
    Paraná512531
    Santa Catarina0033
    Rio Grande do Sul25two3057
    South region3035891

    Source: Health Departments of the States and the Federal District (updated data until 02/27/2016).

    1 Cumulative number of reported cases that met the definition of previous operating case (33 cm), and the definitions adopted in Surveillance Protocol (from 12/09/2015) that defined the Head Circumference 32 cm for newborns 37 or more weeks of gestation and other protocol definitions.
    2 present typical changes: indicative of congenital infection, such as intracranial calcifications, dilation of cerebral ventricles or changes in posterior fossa and other clinical signs observed by any imaging method or identification of Zika virus in laboratory tests.
    3 were confirmed 82 cases by specific laboratory criteria for Zika (PCR and serology technique) virus.
    4 Discarded have normal exams by presenting microcephaly and / or congenital malformations by non-infectious causes or does not meet the case definitions.
    * 5 As stated by the Epidemiological Surveillance Center "Prof. Alexandre Vranjac ", the State Secretary of Health of São Paulo, 162 cases are under investigation for congenital infection. Of these, 39 are possibly associated with infection by Zika virus, but have not yet been finalized investigations.
    * 6 Roraima data related to SE 12, until March 23. (Not updated). 
    Source: Health Departments of the States and the Federal District (updated data until 02/04/2016).


    Amanda Mendes Health Agency 
    Meeting the press 
    (61) 3315-3580 / 2745

    http://combateaedes.saude.gov.br/noticias/510-microcefalia-estudo-aponta-que-1-trimestre-pode-ser-de-maior-risco-para-gravidas

     

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