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Why are all COV 2 vaccines targeting the S? Why not the E?
Isn't that putting all eggs in same basket?
"Engineered knockout or deletion of the E gene has effects ranging from moderate124 to severe293,296 to lethal.105,428 Thus, although E is not always essential, it is critical for coronavirus infectivity"
Fields Virology 6th edition
"Data shows that E is involved in critical aspects of the viral life cycle and that CoVs lacking E make promising vaccine candidates"
Virology Journal Published: 27 May 2019
Coronavirus envelope protein: current knowledge
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