Christer Svensson

Total COVID-19 in Sweden is now 203 https://www.aftonbladet.se/nyheter/a/3Jgxj9/senaste-nytt-om-coronaviruset

Total up to 161 COVID-19 in Sweden https://www.expressen.se/nyheter/minst-3-000-testade-for-corona-i-sverige/

Covid-19 current total 137 cases in Sweden https://www.expressen.se/nyheter/ud-res-inte-till-norra-italien-eller-sydkorea/

COVID-19 cases rise to 94 in Sweden https://www.thelocal.se/20200305/latest-news-about-the-coronavirus-in-sweden-stockholm-gothenburg-orebro-varmland-skane-malmo-lund/amp

Currently 60 COVID-19 cases in Sweden https://www.expressen.se/nyheter/coronasiffrorna-okar-i-sverige-52-smittade/

6 new cases of COVID-19 For a total of 36 in Sweden https://www.expressen.se/nyheter/32-fall-av-coronaviruset-i-sverige/

Cases up by 6, new total is 30 in Sweden https://www.svt.se/nyheter/lokalt/stockholm/ytterligare-sex-bekraftade-coronafall-i-stockholm

Secret carriers of COVID-19 non-symptomatic children ? https://nypost.com/2020/03/02/ex-cdc-head-tom-frieden-says-kids-may-be-secret-coronavirus-carriers/?fbclid=IwAR02ygcSXSRsDeZ7PyskamSQaS3N7u1MJSY3XQ33PBPv5ArxuhjJv5okkSg https://pubs.rsna.org/doi/10.1148/radiol.2020200241

9 new cases of COVID-19 for a total of 24 cases in Sweden https://sverigesradio.se/sida/artikel.aspx?programid=83&artikel=7420297

Yet another COVID-19 case confirmed in Sweden returning from northern Italy https://live.aftonbladet.se/supernytt/news/5e5bd244d6297d00115719cf

As a comment and inquiry refering to this and earlier articles regarding pulmonary autopsy of COVID-19 patients showing obstructed alveoli https://www.globaltimes.cn/content/1181121.shtml Background It is suported by forensic autopsies that alveoli are blocked from effective gas exchange by the formation of mucus in COVID 19 and if I recall correctly other articles mention fibrinous plack formation in SARS hindering oxygen and carbon dioxide perfusion through the semipermeable membrane of the alveoli. A mucolytic treatment strategy For this reason it would in theory be valuable to be able to apply mucus and fibrin solvents "anticoagulants" for coagulatory complexes eg. fibrin and enzymes e.g. [amylase for splitting up mucus carbohydrates] etc. along the air path side to the alveoli [Non mebrane crossing Von vilibrandt factor antagonists] perhaps also on the airway side for solving mucus if extant if and only if these anticoagulants and enzymes, were of a kind that do not cross a semipermeable membrane. For instance [a non membrane crossing modified heparin like molecule ...] Something for Big Pharma to work on. also in conjunction with [ an aerosol mucal solvent treatment ] the manipulation of patient position utilising gravity to empty the visceral pleural sacs of disolved excess mucus fluid. as a hypothetical treatment strategy with the added benefit of bringing more blood and therefore also oxygen to the brain of a patient. Mucus hypersecretionEdit "In the lower respiratory tract excessive mucus production in the bronchi and bronchioles is known as mucus hypersecretion.[10] Chronic mucus hypersecretion results in the chronic productive cough of chronic bronchitis,[15] and is generally synonomous with this.[16] Excess mucus can narrow the airways, limit airflow, and accelerate a decline in lung function.[10]" wikipedia Regarding glycoproteins such as lactoferrin[1] "Binding of biotin-heparin to immobilized lactoferrin" The lactoferrin -heparin interaction may perhaps contribute to incresing mucus viscosity that may interfere with gas perfusion ? https://respiratory-research.biomedcentral.com/articles/10.1186/s12931-019-1239-z

One new COVID-19 case confirmed Stockholm Sweden Connected to female ex-Iran case https://www.expressen.se/nyheter/smittan-fanns-i-italien-utan-att-nagon-upptackte-det1/

4 new cases in Sweden https://epochtimes.se/Fyra-nya-fall-av-coronaviruset-i-Sverige?fbclid=IwAR07yLQjUF0PTen0g592DhZdtqRl9O1-5M3rl6dI3kbuvbdEZPkRcL_hYFo

https://www.sciencedirect.com/science/article/abs/pii/S0166354220300528?via%3Dihub

Contact tracing through antibody assay Duke-NUS @dukenus · 26 feb. "We're proud and happy to help," said Asst Prof Danielle Anderson from @dukenus ' Emerging Infectious Diseases programme. She elaborated how the team developed the #COVID19 serological test kit which helped the Singapore authorities with contact tracing. Contact tracing now possible via novel use of antibody assays https://mobile.twitter.com/dukenus/status/1232459030506786816?s=02 https://www.duke-nus.edu.sg/directory/detail/anderson-danielle-elizabeth

https://www.thelocal.se/20200227/five-new-cases-of-the-coronavirus-in-sweden/amp

Five new cases of COVID-19 in Sweden https://www.aftonbladet.se/nyheter/a/EW9eOA/fem-nya-coronafall-i-sverige-folkhalsomyndigheten-informerar

https://www.reuters.com/article/us-china-health-estonia-case/estonia-says-it-has-first-confirmed-coronavirus-case-tass-idUSKCN20L0L6?il=0

A reporter of the Danish television was confirmed COVID-19 positive https://nyheder.tv2.dk/samfund/2020-02-27-dansker-smittet-med-coronavirus

Noting that for instance Beta-corona viruses like MERS produce a viral load in urine "Low concentrations of the virus were detected in urine" https://link.springer.com/article/10.1007/s00705-014-1995-5?shared-article-renderer It should be of interest to quantify similarly the case for the presence of a COVID19 viral load in urine And possibly advise against the use of public urinoirs which may hypothetically act as aerosolisers.

Ease of spread: Public sanitation facilities may contribute to transmission https://www.bloombergquint.com/global-economics/fecal-transmission-may-be-behind-coronavirus-s-rapid-spread Also 2019-nCoV ACE2 receptor affinity is 10 to 20 fold that of SARS "Surprisingly, ACE2 bound to 2019-nCoV S ectodomain with ∼15 nM affinity, which is approximately 10- to 20-fold higher affinity than ACE2 binding to SARS-CoV S" "The high affinity of 2019-nCoV S for human ACE2 may contribute to the apparent ease with which 2019-nCoV can spread from human-to-human(1), however additional studies are needed to investigate this possibility." https://www.biorxiv.org/content/10.1101/2020.02.11.944462v1.full

https://www.thelocal.se/20200131/first-case-of-coronavirus-confirmed-in-jonkoping-sweden/amp in english

https://www.svd.se/bekraftat-fall-i-jonkoping-av-nya-coronaviruset

https://www.folkhalsomyndigheten.se/nyheter-och-press/nyhetsarkiv/2020/januari/bekraftat-fall-av-nytt-coronavirus-i-sverige/

First verified 2019-nCoV in Finland https://svenska.yle.fi/artikel/2020/01/29/thl-kinesisk-resenar-bekraftas-ha-coronaviruset-forsta-fallet-i-finland