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Ninth BA.2.86 Sequence from Gauteng South Africa


niman

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P323L/G671S mutation in NSP12 provides significant replication advantages in the upper respiratory tract to become prevalent relative to other strains in an in vivo competitive transmission assay with NSP12 wild-type (WT) or NSP12 mutant-containing reverse genetic (RG) SARS-CoV-2 viruses.

https://www.cell.com/cell-reports/fulltext/S2211-1247(23)01088-4?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS2211124723010884%3Fshowall%3Dtrue

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