Jon Schultz Posted March 24, 2020 Report Share Posted March 24, 2020 The coronavirus isn’t mutating quickly, suggesting a vaccine would offer lasting protection Dr. Niman, please comment on this story: https://www.washingtonpost.com/health/the-coronavirus-isnt-mutating-quickly-suggesting-a-vaccine-would-offer-lasting-protection/2020/03/24/406522d6-6dfd-11ea-b148-e4ce3fbd85b5_story.html Link to comment Share on other sites More sharing options...
J Enders Posted March 25, 2020 Report Share Posted March 25, 2020 I would certainly defer to Dr. Niman, but my understanding is that an RNA virus such as coronavirus is prone to error in replication i.e. mutation. This virus is highly transmissible and will therefore have achieved a large reservoir of hosts. A vaccine may work but may also introduce selection pressure such that mutations unfavorable to the hosts (humans) proliferate. Link to comment Share on other sites More sharing options...
Jon Schultz Posted March 25, 2020 Author Report Share Posted March 25, 2020 (edited) Thanks. What I would most like Dr. Niman to comment on is why most virologists, according to the article, aren't accepting the proposition that there are different strains with different severity and/or transmission characteristics. Dr. Niman seems convinced that the strain in Italy (and now other countries) is more deadly, whereas others are attributing the higher case fatality rate in Italy to other factors. Edited March 25, 2020 by Jon Schultz Link to comment Share on other sites More sharing options...
Jon Schultz Posted March 26, 2020 Author Report Share Posted March 26, 2020 Also, Dr. Niman, do you think one vaccine will work for both of the current two main lineages you described to Jeff Rense last night? And if they're only going to create one vaccine, do you think it's important that they base it on the "Italian strain"? Link to comment Share on other sites More sharing options...
niman Posted March 29, 2020 Report Share Posted March 29, 2020 On 3/24/2020 at 6:48 PM, Jon Schultz said: The coronavirus isn’t mutating quickly, suggesting a vaccine would offer lasting protection Dr. Niman, please comment on this story: https://www.washingtonpost.com/health/the-coronavirus-isnt-mutating-quickly-suggesting-a-vaccine-would-offer-lasting-protection/2020/03/24/406522d6-6dfd-11ea-b148-e4ce3fbd85b5_story.html Same comments were made for SARS. Coronaviruses recombine frequently and will quickly evolve away from a vaccine. Link to comment Share on other sites More sharing options...
Jon Schultz Posted April 15, 2020 Author Report Share Posted April 15, 2020 I imagine you've seen this article, Dr. Niman, but if not: https://www.scmp.com/news/china/science/article/3079678/coronavirus-mutation-threatens-race-develop-vaccine Coronavirus mutation could threaten the race to develop vaccine A strain found in India showed changes in the mechanism used to bind the virus to human cells which could render current research futile Researchers are targeting the same process that allowed Sars to infect people, but the mutation could upend their assumptions Link to comment Share on other sites More sharing options...
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