niman

https://coronavirus.iowa.gov/#CurrentStatus

USA/MD-MDH-1151/2021 2/9 Maryland matched 501.v2 with 3 AAs deleted in Spike protein, 3 AAs deleted in NSP6 map update https://www.google.com/maps/d/u/1/edit?mid=1aQDSL2LwQFbuoCAg_nIOPK8D-LIJ5MYd&ll=39.166673895309756%2C-76.72971723808188&z=10

USA/MD-MDH-1082/2021 2/20 Maryland matched 501.v2 with 3 AAs deleted in Spike protein, 3 AAs deleted in NSP6 map update https://www.google.com/maps/d/u/1/edit?mid=1aQDSL2LwQFbuoCAg_nIOPK8D-LIJ5MYd&ll=39.166673895309756%2C-76.72971723808188&z=10

USA/MD-MDH-1080/2021 2/19 Maryland matched 501.v2 with 3 AAs deleted in Spike protein, 3 AAs deleted in NSP6 map update https://www.google.com/maps/d/u/1/edit?mid=1aQDSL2LwQFbuoCAg_nIOPK8D-LIJ5MYd&ll=39.166673895309756%2C-76.72971723808188&z=10

Maryland Public Health Laboratory has released (at GISAID) three B.1.351 sequences collected Feb 9-20 USA/MD-MDH-1080/2021 2/19 Maryland USA/MD-MDH-1082/2021 2/20 Maryland USA/MD-MDH-1151/2021 2/9 Maryland

USA/OR-OHSU-UNK1004/2021 Douglas County Oregon USA/OR-CDC-2-3846542/2021 map update https://www.google.com/maps/d/u/1/edit?mid=1aQDSL2LwQFbuoCAg_nIOPK8D-LIJ5MYd&ll=42.92453375520405%2C-124.18127831196594&z=8

The P.1 variant described below has not been released. The assigned UNK number will be updated upon release. USA/OR-CDC-2-3846542/2021 USA/OR-OHSU-UNK1004/2021 Douglas County Oregon Dr. Bob Dannenhoffer, our Douglas County Public Health Officer, has confirmed the first positive case related to the COVID-19 P.1 variant in Douglas County. This cases marks the first case of the P.1 variant in Oregon, as well as the first case on the west coast of the United States. There have only been 10 other cases of the P.1 variant reported in the United States, in Minnesota (2), Florida (5), Oklahoma (1), Alaska (1) and Maryland (1). The P.1 variant confirmed last night from a swab sent to the U.S. Center for Disease Control (CDC) for genome sequence testing, appears to be related to business travel outside the United States to and from Brazil. http://www.douglascountyor.us/apps/media_room/coronavirus/press_releases/3-02-2021 DCCRT DAILY UPDATE COVID-19.pdf

USA/OR-KCL-21012586COV_06/2021 1/25 85M Sublimity matched B.1.1.7 variant with 3 AAs deleted in Spike protein, 3 AAs deleted in NSP 6 and Q27 stop codon in NS8. map update https://www.google.com/maps/d/u/1/edit?mid=1aQDSL2LwQFbuoCAg_nIOPK8D-LIJ5MYd&ll=44.64108793196928%2C-122.95661056506857&z=9

Kashi Clinical Laboratory has released (at GISAID) a UK variant (B.1.1.7) sequence collected Jan 25 USA/OR-KCL-21012586COV_06/2021 1/25 85M Sublimity

Discovered in a patient in Portland, it is similar to the U.K. strain but carries a mutation seen in variants of the virus being spread in South Africa, Brazil and New York City. This mutation has also already been observed in Britain. The mutation was in a sample scientists collected from an outbreak in a health care setting. Of the 13 samples analyzed, 10 were the U.K. strain and one was the new mutation. https://www.usnews.com/news/health-news/articles/2021-03-05/scientists-discover-mutation-of-uk-coronavirus-strain-in-oregon

Discovered in a patient in Portland, it is similar to the U.K. strain but carries a mutation seen in variants of the virus being spread in South Africa, Brazil and New York City. This mutation has also already been observed in Britain. The mutation was in a sample scientists collected from an outbreak in a health care setting. Of the 13 samples analyzed, 10 were the U.K. strain and one was the new mutation. https://www.usnews.com/news/health-news/articles/2021-03-05/scientists-discover-mutation-of-uk-coronavirus-strain-in-oregon

Discovered in a patient in Portland, it is similar to the U.K. strain but carries a mutation seen in variants of the virus being spread in South Africa, Brazil and New York City. This mutation has also already been observed in Britain. The mutation was in a sample scientists collected from an outbreak in a health care setting. Of the 13 samples analyzed, 10 were the U.K. strain and one was the new mutation. https://www.usnews.com/news/health-news/articles/2021-03-05/scientists-discover-mutation-of-uk-coronavirus-strain-in-oregon

USA/NY-PRL-2021_0210_04E07/2021 2/8 M New York City matched B.1.1.7 variant with 3 AAs deleted in Spike protein, 3 AAs deleted in NSP 6 and Q27 stop codon in NS8 (but this is a recombinant and has lost N501Y and A580D) Map Update https://www.google.com/maps/d/u/1/edit?mid=1aQDSL2LwQFbuoCAg_nIOPK8D-LIJ5MYd&ll=40.70750215419051%2C-73.94706679027408&z=12

PRI has released (at GISAID) a UK variant (B.1.1.7) sequence collected Feb 8 USA/NY-PRL-2021_0210_04E07/2021 2/8 M New York City

The researchers have so far found just a single case of this formidable combination, but genetic analysis suggested that the variant had been acquired in the community and did not arise in the patient. “We didn’t import this from elsewhere in the world — it occurred spontaneously,” said Brian O’Roak, a geneticist at Oregon Health and Science University who led the work. He and his colleagues participate in the Centers for Disease Control and Prevention’s effort to track variants, and they have deposited their results in databases shared by scientists. The variant originally identified in Britain, called B.1.1.7, has been spreading rapidly across the United States, and accounts for at least 2,500 cases in 46 states. This form of the virus is both more contagious, and more deadly, than the original version, and is expected to account for most infections in America in a few weeks. The new version that surfaced in Oregon has the same backbone, but also a mutation — E484K, or “Eek” — seen in variants of the virus circulating in South Africa, Brazil and New York City. Lab studies and clinical trials in South Africa indicate that the Eek mutation renders the current vaccines less effective by blunting the body’s immune response. (The vaccines still work, but the findings are worrying enough that Pfizer-BioNTech and Moderna have begun testing new versions of their vaccines designed to defeat the variant found in South Africa.) The B.1.1.7 variant with Eek also has emerged in Britain, designated as a “variant of concern” by scientists. But the virus identified in Oregon seems to have evolved independently, Dr. O’Roak said. Dr. O’Roak and his colleagues found the variant among coronavirus samples collected by the Oregon State Public Health Lab across the state, including some from an outbreak in a health care setting. Of the 13 test results they analyzed, 10 turned out to be B.1.1.7 alone, and one the combination. Other experts said the discovery was not surprising, because the Eek mutation has arisen in forms of the virus all over the world. But the mutation’s occurrence in B.1.1.7 is worth watching, they said. In Britain, this version of the variant accounts for a small number of cases. But by the time the combination evolved there, B.1.1.7 had already spread through the country. “We’re at the point where B.1.1.7 is just being introduced” into the United States, said Stacia Wyman, an expert in computational genomics at the University of California, Berkeley. “As it evolves, and as it slowly becomes the dominant thing, it could accumulate more mutations.” Viral mutations may enhance or weaken one another. For example, the variants identified in South Africa and Brazil contain many of the same mutations, including Eek. But the Brazilian version has a mutation, K417N, that is not present in the version from South Africa. In a study published Thursday in Nature, researchers compared antibody responses to all three variants of concern — the ones identified in Britain, South Africa and Brazil. Consistent with other studies, they found that the variant that pummeled South Africa is most resistant to antibodies produced by the immune system. But the variant circulating in Brazil was not as resistant, even though it carried the Eek mutation. “If you have the second mutation, you don’t see as bad an effect,” said Michael Diamond, a viral immunologist at Washington University in St. Louis, who led the study. It’s too early to say whether the variant in Oregon will behave like the ones in South Africa or Brazil. But the idea that other mutations could weaken Eek’s effect is “excellent news,” Dr. Wyman said. Over all, she said, the Oregon finding reinforces the need for people to continue to take precautions, like wearing a mask, until a substantial portion of the population is immunized. “People need to not freak out but to continue to be vigilant,” she said. “We can’t let down our guard yet while there’s still these more transmissible variants circulating.” Apoorva Mandavilli is a reporter focusing on science and global health. She is the 2019 winner of the Victor Cohn Prize for Excellence in Medical Science Reporting. @apoorva_nyc A version of this article appears in print on March 6, 2021, Section A, Page 6 of the New York edition with the headline: Variant Seen In Oregon Has Mutation Like in U.K.. Order Reprints | Today’s Paper | Subscribe

In Oregon, Scientists Find a Virus Variant With a Worrying Mutation In a single sample, geneticists discovered a version of the coronavirus first identified in Britain with a mutation originally reported in South Africa. By Apoorva Mandavilli March 5, 2021 Scientists in Oregon have spotted a homegrown version of a fast-spreading variant of the coronavirus that first surfaced in Britain — but now combined with a mutation that may make the variant less susceptible to vaccines. https://www.nytimes.com/2021/03/05/health/virus-oregon-variant.html

There are 524,903 confirmed COVID-19 patients in Missouri, including 8,762 deaths. https://www.kshb.com/news/coronavirus/covid-19-case-tracker-where-we-stand-in-mo-ks-nationwide Adair County 2,321 20 Andrew County 1,953 20 Atchison County 290 6 Audrain County 2,080 57 Barry County 3,048 52 Barton County 973 12 Bates County 1,087 23 Benton County 1,453 27 Bollinger County 1,188 17 Boone County 17,506 84 Buchanan County 7,119 172 Butler County 4,302 41 Caldwell County 641 11 Callaway County 4,502 45 Camden County 3,733 81 Cape Girardeau County 7,607 132 Carroll County 836 23 Carter County 424 9 Cass County 7,282 91 Cedar County 705 19 Chariton County 424 6 Christian County 7,005 80 Clark County 472 6 Clay County 9,623 151 Clinton County 1,529 65 Cole County 8,602 118 Cooper County 1,693 27 Crawford County 2,060 32 Dade County 420 14 Dallas County 830 24 Daviess County 587 11 DeKalb County 924 27 Dent County 822 17 Douglas County 772 26 Dunklin County 3,355 26 Franklin County 8,998 164 Gasconade County 883 41 Gentry County 734 21 Greene County 27,770 436 Grundy County 829 34 Harrison County 823 14 Henry County 1,750 37 Hickory County 467 13 Holt County 503 15 Howard County 725 7 Howell County 2,830 42 Iron County 465 5 Jackson County 30,257 388 Jasper County 14,909 273 Jefferson County 21,769 224 Johnson County 4,650 45 Knox County 179 2 Laclede County 2,929 66 Lafayette County 2,582 57 Lawrence County 2,764 76 Lewis County 631 10 Lincoln County 4,606 61 Linn County 548 12 Livingston County 1,331 37 McDonald County 2,459 31 Macon County 1,213 15 Madison County 1,348 16 Maries County 537 7 Marion County 2,652 42 Mercer County 179 2 Miller County 2,322 49 Mississippi County 1,660 30 Moniteau County 1,885 29 Monroe County 598 10 Montgomery County 568 10 Morgan County 1,632 42 New Madrid County 2,054 50 Newton County 5,243 83 Nodaway County 2,580 25 Oregon County 676 3 Osage County 1,408 14 Ozark County 552 16 Pemiscot County 1,628 38 Perry County 2,126 32 Pettis County 4,962 75 Phelps County 3,032 121 Pike County 1,490 22 Platte County 3,144 43 Polk County 2,182 31 Pulaski County 5,951 48 Putnam County 225 3 Ralls County 759 12 Randolph County 1,821 30 Ray County 1,522 25 Reynolds County 261 3 Ripley County 857 14 St. Charles County 35,621 442 St. Clair County 590 7 Ste. Genevieve County 1,738 18 St. Francois County 7,603 107 St. Louis County 89,030 2,018 Saline County 2,799 54 Schuyler County 277 5 Scotland County 263 3 Scott County 3,917 77 Shannon County 483 12 Shelby County 355 7 Stoddard County 3,085 62 Stone County 2,031 38 Sullivan County 748 14 Taney County 4,600 90 Texas County 1,545 22 Vernon County 1,397 38 Warren County 2,670 27 Washington County 2,122 48 Wayne County 821 11 Webster County 2,998 53 Worth County 143 1 Wright County 1,365 29 St. Louis city 19,986 428 Kansas City 37,090 528 Note: Positive cases and deaths reported by the Joplin Health Department are included with the Jasper County Health Department figures.

https://alaska-coronavirus-vaccine-outreach-alaska-dhss.hub.arcgis.com/

https://health.wyo.gov/publichealth/infectious-disease-epidemiology-unit/disease/novel-coronavirus/covid-19-map-and-statistics/

https://montana.maps.arcgis.com/apps/MapSeries/index.html?appid=7c34f3412536439491adcc2103421d4b

https://health.hawaii.gov/coronavirusdisease2019/

https://www.health.nd.gov/diseases-conditions/coronavirus/north-dakota-coronavirus-cases

New Cases 126 15,819 Total Currently Hospitalized 26 Hospitalized In ICU 4 Hospitalized Under Investigation 0 Percent Positive 7-day Avg. 1.6% People Tested 334,096 Total Tests 1,107,296 Recovered 13,145 83.1% of Cases Deaths 207 1.3% of Cases https://www.healthvermont.gov/covid-19/current-activity/vermont-dashboard

Cumulative COVID-19 Cases by County Download a csv file with the most recent cumulative case data by county. Download a csv file with historical case data by county and date. Maine COVID-19 Reopening Gating Metrics Cumulative COVID-19 Cases by ZIP Code Download a csv file with the most recent cumulative case data by zip code. Tables of COVID-19 Testing and Contact Tracing Data, Hospital Use, and Case Demographics View a Table of Contact Tracing (Sara Alert) Data Contact Tracing (Sara Alert) Data Number of Individuals Currently in Monitoring Total Number of Individuals Enrolled 2,643 57,629 Maine CDC updates contact tracing data weekly. Updated March 4, 2021 at 10:41 AM. https://www.maine.gov/dhhs/mecdc/infectious-disease/epi/airborne/coronavirus/data.shtml

New Hampshire 2019 Novel Coronavirus (COVID-19) Summary Report (data updated as of March 5, 2021- 9:00 AM) https://www.nh.gov/covid19/ Number of Persons with COVID-19 1 76,422 Recovered 73,004 (96%) Deaths Attributed to COVID-19 1,178 (2%) Total Current COVID-19 Cases 2,240 Current Hospitalizations 90 Total Persons Tested at Selected Laboratories, Polymerase Chain Reaction (PCR)2 631,445 Total Persons Tested at Selected Laboratories, Antibody Laboratory Tests2 37,863 Persons with Specimens Submitted to NH PHL 68,920 Persons with Test Pending at NH PHL3 271 1 Includes specimens positive at any laboratory and those confirmed by CDC confirmatory testing. 2 Includes specimens tested at the NH Public Health Laboratories (PHL), LabCorp, Quest, Dartmouth-Hitchcock Medical Center, Mako, certain hospital laboratories, the University of New Hampshire and their contracted laboratory, and those sent to CDC prior to NH PHL testing capacity. 3 Includes specimens received and awaiting testing at NH PHL. Does not include tests pending at commercial laboratories. The Latest Active Cases Data The Latest Active Cases Map The Latest Cumulative Cases Data The Latest Cumulative Cases Map NH DHHS Anno