niman

Sequences producing significant alignments: Select:AllNone Selected:0 AlignmentsDownloadGenBankGraphicsDistance tree of resultsShow/hide columns of the table presenting sequences producing significant alignments Sequences producing significant alignments: Select for downloading or viewing reports Description Max score Total score Query cover E value Ident Accession Select seq gb|KX838906.1| Zika virus isolate ZIKV/Aedes_aegypti/USA/2016/ZM3-7729 polyprotein gene, complete cds 18493 18493 100% 0.0 99% KX838906.1 Select seq gb|KX673530.1| Zika virus isolate PHE_semen_Guadeloupe, complete genome 18420 18420 100% 0.0 99% KX673530.1 Select seq gb|KU853013.1| Zika virus isolate Dominican Republic/2016/PD2, complete genome 18417 18417 100% 0.0 99% KU853013.1 Select seq gb|KU853012.1| Zika virus isolate Dominican Republic/2016/PD1, complete genome 18415 18415 100% 0.0 99% KU853012.1 Select seq gb|KX842449.1| Zika virus isolate ZIKV/Human/USA/2016/ZF10.UR-010 polyprotein gene, complete cds 18408 18408 100% 0.0 99% KX842449.1 Select seq gb|KX838905.1| Zika virus isolate ZIKV/Aedes_aegypti/USA/2016/ZM2-7719 polyprotein gene, complete cds 18402 18402 100% 0.0 99% KX838905.1 Select seq gb|KX838904.1| Zika virus isolate ZIKV/Aedes_aegypti/USA/2016/ZM1-7501 polyprotein gene, complete cds 18399 18399 100% 0.0 99% KX838904.1 Select seq gb|KX832731.1| Zika virus isolate ZIKV/Human/USA/2016/ZL2.SA-Hu0015 polyprotein gene, complete cds 18399 18399 100% 0.0 99% KX832731.1 Select seq gb|KX447510.1| Zika virus isolate 1_0049_PF polyprotein gene, complete cds 18327 18327 100% 0.0 99% KX447510.1 Select seq gb|KX280026.1| Zika virus isolate Paraiba_01, complete genome 18321 18321 100% 0.0 99% KX280026.1 Select seq gb|KU729217.2| Zika virus isolate BeH823339 polyprotein gene, complete cds 18321 18321 100% 0.0 99% KU729217.2 Select seq gb|KX447512.1| Zika virus isolate 1_0181_PF polyprotein gene, complete cds 18318 18318 100% 0.0 99% KX447512.1 Select seq gb|KX369547.1| Zika virus strain PF13/251013-18, complete genome 18318 18318 100% 0.0 99% KX369547.1 Select seq gb|KU509998.3| Zika virus strain Haiti/1225/2014, complete genome 18318 18318 100% 0.0 99% KU509998.3 Select seq gb|KJ776791.2| Zika virus strain H/PF/2013, complete genome 18312 18312 100% 0.0 99% KJ776791.2 Select seq gb|KX447509.1| Zika virus isolate 1_0087_PF polyprotein gene, complete cds 18312 18312 100% 0.0 99% KX447509.1 Select seq gb|KU991811.1| Zika virus isolate Brazil/2016/INMI1 polyprotein gene, complete cds 18312 18312 100% 0.0 99% KU991811.1 Select seq gb|KX447513.1| Zika virus isolate 1_0134_PF polyprotein gene, complete cds 18309 18309 100% 0.0 99% KX447513.1 Select seq gb|KX811222.1| Zika virus isolate Brazil_2015_MG, complete genome 18303 18303 100% 0.0 99% KX811222.1 Select seq gb|KX197205.1| Zika virus isolate 9, complete genome 18303 18303 100% 0.0 99% KX197205.1 Select seq gb|KX447515.1| Zika virus isolate 1_0030_PF polyprotein gene, complete cds 18303 18303 100% 0.0 99% KX447515.1 Select seq gb|KX447511.1| Zika virus isolate 1_0015_PF polyprotein gene, complete cds 18303 18303 100% 0.0 99% KX447511.1 Select seq gb|KU321639.1| Zika virus strain ZikaSPH2015, complete genome 18303 18303 100% 0.0 99% KU321639.1 Select seq gb|KX879604.1| Zika virus isolate SN089, complete genome 18300 18300 100% 0.0 99% KX879604.1 Select seq gb|KX447514.1| Zika virus isolate 1_0035_PF polyprotein gene, complete cds 18300 18300 100% 0.0 99% KX447514.1 Select seq gb|KX051563.1| Zika virus isolate Haiti/1/2016, complete genome 18300 18300 100% 0.0 99% KX051563.1 Select seq gb|KX447516.1| Zika virus isolate 1_0111_PF polyprotein gene, complete cds 18294 18294 100% 0.0 99% KX447516.1 Select seq gb|KU729218.1| Zika virus isolate BeH828305 polyprotein gene, complete cds 18294 18294 100% 0.0 99% KU729218.1 Select seq gb|KU707826.1| Zika virus isolate SSABR1, complete genome 18294 18294 100% 0.0 99% KU707826.1 Select seq gb|KU527068.1| Zika virus strain Natal RGN, complete genome 18294 18294 100% 0.0 99% KU527068.1 Select seq gb|KU365779.1| Zika virus strain BeH819966 polyprotein gene, complete cds 18294 18294 100% 0.0 99% KU365779.1 Select seq gb|KX879603.1| Zika virus isolate SN062, complete genome 18291 18291 100% 0.0 99% KX879603.1 Select seq gb|KX262887.1| Zika virus isolate 103451, complete genome 18291 18291 100% 0.0 99% KX262887.1 Select seq gb|KX197192.1| Zika virus isolate ZIKV/H.sapiens/Brazil/PE243/2015, complete genome 18291 18291 100% 0.0 99% KX197192.1 Select seq gb|KU926310.1| Zika virus isolate Rio-S1, complete genome 18291 18291 100% 0.0 99% KU926310.1 Select seq gb|KU926309.1| Zika virus isolate Rio-U1, complete genome 18291 18291 100% 0.0 99% KU926309.1 Select seq gb|KU940228.1| Zika virus isolate Bahia07, partial genome 18285 18285 100% 0.0 99% KU940228.1 Select seq gb|KX694534.1| Zika virus strain ZIKV/Homo sapiens/HND/R103451/2015, complete genome 18282 18282 100% 0.0 99% KX694534.1 Select seq gb|KX447517.1| Zika virus isolate 1_0038_PF polyprotein gene, complete cds 18282 18282 100% 0.0 99% KX447517.1 Select seq gb|KX247646.1| Zika virus isolate Zika virus/Homo sapiens/COL/UF-1/2016, complete genome 18282 18282 100% 0.0 99% KX247646.1 Select seq gb|KX198135.1| Zika virus strain ZIKV/Homo sapiens/PAN/BEI-259634_V4/2016, complete genome 18282 18282 100% 0.0 99% KX198135.1 Select seq gb|KX156776.1| Zika virus strain ZIKV/Homo sapiens/PAN/CDC-259364_V1-V2/2015, complete genome 18282 18282 100% 0.0 99% KX156776.1 Select seq gb|KU501217.1| Zika virus strain 8375 polyprotein gene, complete cds 18282 18282 100% 0.0 99% KU501217.1 Select seq gb|KU365780.1| Zika virus strain BeH815744 polyprotein gene, complete cds 18282 18282 100% 0.0 99% KU365780.1 Select seq gb|KX156774.1| Zika virus strain ZIKV/Homo sapiens/PAN/CDC-259359_V1-V3/2015, complete genome 18276 18276 100% 0.0 99% KX156774.1 Select seq gb|KU647676.1| Zika virus strain MRS_OPY_Martinique_PaRi_2015 polyprotein gene, complete cds 18276 18276 100% 0.0 99% KU647676.1 Select seq gb|KU501216.1| Zika virus strain 103344 polyprotein gene, complete cds 18276 18276 100% 0.0 99% KU501216.1 Select seq gb|KU365777.1| Zika virus strain BeH818995 polyprotein gene, complete cds 18276 18276 100% 0.0 99% KU365777.1 Select seq gb|KU820897.5| Zika virus isolate FLR polyprotein gene, complete cds 18273 18273 100% 0.0 99% KU820897.5 Select seq gb|KU758877.1| Zika virus isolate 17271 polyprotein gene, complete cds 18273 18273 100% 0.0 99% KU758877.1 Select seq gb|KX247632.1| Zika virus isolate MEX_I_7 polyprotein gene, complete cds 18273 18273 100% 0.0 99% KX247632.1 Select seq gb|KX156775.1| Zika virus strain ZIKV/Homo sapiens/PAN/CDC-259249_V1-V3/2015, complete genome 18273 18273 100% 0.0 99% KX156775.1 Select seq gb|KX087102.1| Zika virus strain ZIKV/Homo sapiens/COL/FLR/2015, complete genome 18273 18273 100% 0.0 99% KX087102.1 Select seq gb|KU497555.1| Zika virus isolate Brazil-ZKV2015, complete genome 18269 18269 99% 0.0 99% KU497555.1 Select seq gb|KX520666.1| Zika virus isolate HS-2015-BA-01 polyprotein gene, complete cds 18267 18267 100% 0.0 99% KX520666.1 Select seq gb|KX856011.1| Zika virus strain ZIKV/Aedes sp./MEX_I-44/2016, complete genome 18264 18264 100% 0.0 99% KX856011.1 Select seq gb|KX446951.1| Zika virus strain ZIKV/Aedes.sp/MEX/MEX_I-7/2016, complete genome 18264 18264 100% 0.0 99% KX446951.1 Select seq gb|KU501215.1| Zika virus strain PRVABC59, complete genome 18264 18264 100% 0.0 99% KU501215.1 Select seq gb|KU365778.1| Zika virus strain BeH819015 polyprotein gene, complete cds 18264 18264 100% 0.0 99% KU365778.1 Select seq gb|KU312312.1| Zika virus isolate Z1106033 polyprotein gene, complete cds 18264 18264 100% 0.0 99% KU312312.1 Select seq gb|KX601168.1| Zika virus strain ZIKV/Homo Sapiens/PRI/PRVABC59/2015, complete genome 18258 18258 100% 0.0 99% KX601168.1 Select seq gb|KX446950.1| Zika virus strain ZIKV/Aedes.sp/MEX/MEX_2-81/2016, complete genome 18258 18258 100% 0.0 99% KX446950.1 Select seq gb|KX087101.2| Zika virus strain ZIKV/Homo sapiens/PRI/PRVABC59/2015, complete genome 18258 18258 100% 0.0 99% KX087101.2 Select seq gb|KU922960.1| Zika virus isolate MEX/InDRE/Sm/2016, complete genome 18258 18258 100% 0.0 99% KU922960.1 Select seq gb|KX806557.1| Zika virus isolate TS17-2016, complete genome 18254 18254 100% 0.0 99% KX806557.1 Select seq gb|KX702400.1| Zika virus strain Zika virus/Homo sapiens/VEN/UF-1/2016, complete genome 18254 18254 100% 0.0 99% KX702400.1 Select seq gb|KX548902.1| Zika virus isolate ZIKV/COL/FCC00093/2015 polyprotein gene, complete cds 18254 18254 100% 0.0 99% KX548902.1 Select seq gb|KX377337.1| Zika virus strain PRVABC-59, complete genome 18254 18254 100% 0.0 99% KX377337.1 Select seq gb|KU937936.1| Zika virus isolate ZIKVNL00013 polyprotein gene, complete cds 18254 18254 100% 0.0 99% KU937936.1 Select seq gb|KU922923.1| Zika virus isolate MEX/InDRE/Lm/2016, complete genome 18254 18254 100% 0.0 99% KU922923.1 Select seq gb|KU870645.1| Zika virus isolate FB-GWUH-2016, complete genome 18249 18249 100% 0.0 99% KU870645.1 Select seq gb|KX766029.1| Zika virus isolate R116265, complete genome 18245 18245 100% 0.0 99% KX766029.1 Select seq gb|KU820898.1| Zika virus isolate GZ01 polyprotein gene, complete cds 18236 18236 100% 0.0 99% KU820898.1 Select seq gb|KX056898.1| Zika virus isolate Zika virus/GZ02/2016 polyprotein gene, complete cds 18231 18231 100% 0.0 99% KX056898.1 Select seq gb|KU955590.1| Zika virus isolate Z16019 polyprotein gene, complete cds 18231 18231 100% 0.0 99% KU955590.1 Select seq gb|KX766028.1| Zika virus isolate R114916, complete genome 18229 18229 100% 0.0 99% KX766028.1 Select seq gb|KU740184.2| Zika virus isolate GD01 polyprotein gene, complete cds 18227 18227 100% 0.0 99% KU740184.2 Select seq gb|KU761564.1| Zika virus isolate GDZ16001 polyprotein gene, complete cds 18227 18227 100% 0.0 99% KU761564.1 Select seq gb|KX117076.1| Zika virus isolate Zhejiang04, complete genome 18222 18222 100% 0.0 99% KX117076.1 Select seq gb|KX185891.1| Zika virus isolate Zika virus/CN/SZ02/2016 polyprotein gene, complete cds 18213 18213 100% 0.0 99% KX185891.1 Select seq gb|KU963796.1| Zika virus isolate SZ-WIV01 polyprotein gene, complete cds 18213 18213 100% 0.0 99% KU963796.1 Select seq gb|KX253996.1| Zika virus isolate ZKC2/2016, complete genome 18209 18209 100% 0.0 99% KX253996.1 Select seq gb|KU955589.1| Zika virus isolate Z16006 polyprotein gene, complete cds 18209 18209 100% 0.0 99% KU955589.1 Select seq gb|KU820899.2| Zika virus isolate ZJ03, complete genome 18209 18209 100% 0.0 99% KU820899.2 Select seq gb|KX266255.1| Zika virus isolate ZIKV_SMGC-1, complete genome 18206 18206 100% 0.0 99% KX266255.1 Select seq gb|KU866423.2| Zika virus isolate Zika virus/SZ01/2016/China polyprotein gene, complete cds 18204 18204 100% 0.0 99% KU866423.2 Select seq gb|KU940224.1| Zika virus isolate Bahia09, partial genome 18191 18191 99% 0.0 99% KU940224.1 Select seq gb|KU744693.1| Zika virus isolate VE_Ganxian, complete genome 18069 18069 100% 0.0 99% KU744693.1 Select seq gb|KX827309.1| Zika virus isolate ZKA-16-291 polyprotein gene, complete cds 18056 18056 100% 0.0 99% KX827309.1 Select seq gb|KX813683.1| Zika virus isolate ZKA-16-097 polyprotein gene, complete cds 18042 18042 100% 0.0 99% KX813683.1 Select seq gb|KU681081.3| Zika virus isolate Zika virus/H.sapiens-tc/THA/2014/SV0127- 14, complete genome 17988 17988 100% 0.0 99% KU681081.3 Select seq gb|KX694532.1| Zika virus strain ZIKV/Homo sapiens/THA/PLCal_ZV/2013, complete genome 17867 17867 100% 0.0 99% KX694532.1 Select seq gb|KU955593.1| Zika virus isolate Zika virus/H.sapiens-tc/KHM/2010/FSS13025, complete genome 17672 17672 100% 0.0 98% KU955593.1 Select seq gb|JN860885.1| Zika virus isolate FSS13025 polyprotein gene, partial cds 17672 17672 99% 0.0 98% JN860885.1 Select seq gb|KF993678.1| Zika virus strain PLCal_ZV from Canada polyprotein gene, partial cds 17634 17634 98% 0.0 99% KF993678.1 Select seq gb|EU545988.1| Zika virus polyprotein gene, complete cds 17526 17526 100% 0.0 98% EU545988.1 Select seq gb|KU681082.3| Zika virus isolate Zika virus/H.sapiens-tc/PHL/2012/CPC-0740, complete genome 17380 17380 100% 0.0 98% KU681082.3 Select seq gb|KX601167.1| Zika virus strain ZIKV/Aedes sp./MYS/P6-740/1966, complete genome 16361 16361 100% 0.0 95% KX601167.1 Select seq gb|KX694533.1| Zika virus strain ZIKV/Aedes aegypti/MYS/P6-740/1966, complete genome 16352 16352 100% 0.0 95% KX694533.1 Select seq gb|HQ234499.1| Zika virus isolate P6-740 polyprotein gene, partial cds 16352 16352 99% 0.0 95% HQ234499.1

LOCUS KX922708 10606 bp RNA linear VRL 05-OCT-2016 DEFINITION Zika virus isolate ZIKV/Aedes_aegypti/USA/2016/FL04M polyprotein gene, complete cds. ACCESSION KX922708 VERSION KX922708.1 GI:1071930520 DBLINK BioProject: PRJNA342539 BioSample: SAMN05853067 KEYWORDS . SOURCE Zika virus ORGANISM Zika virus Viruses; ssRNA viruses; ssRNA positive-strand viruses, no DNA stage; Flaviviridae; Flavivirus. REFERENCE 1 (bases 1 to 10606) AUTHORS Grubaugh,N., Paul,L., Porcelli,M., Vasquez,C., Gangavarupu,K., Oliveira,G., Robles-Sikisaka,R., Michael,S., Isern,S. and Andersen,K. TITLE Zika virus sequences from Florida, USA, 2016 JOURNAL Unpublished REFERENCE 2 (bases 1 to 10606) AUTHORS Grubaugh,N., Paul,L., Porcelli,M., Vasquez,C., Gangavarupu,K., Oliveira,G., Robles-Sikisaka,R., Michael,S., Isern,S. and Andersen,K. TITLE Direct Submission JOURNAL Submitted (29-SEP-2016) Department of Immunology and Microbial Science, The Scripps Research Institute, 10550 North Torrey Pines Road, IMM-210, La Jolla, CA 92037, USA COMMENT ##Assembly-Data-START## Assembly Method :: NovoAlign v. V3.04 Sequencing Technology :: Illumina ##Assembly-Data-END## FEATURES Location/Qualifiers source 1..10606 /organism="Zika virus" /mol_type="genomic RNA" /isolate="ZIKV/Aedes_aegypti/USA/2016/FL04M" /isolation_source="pool of 50 adult mosquitoes" /host="Aedes aegypti" /db_xref="taxon:64320" /country="USA: Miami, Florida" /collection_date="04-Sep-2016" CDS 81..10352 /codon_start=1 /product="polyprotein" /protein_id="AOS90225.1" /db_xref="GI:1071930521" /translation="MKNPKKKSGGFRIVNMLKRGVARVSPFGGLKRLPAGLLLGHGPI RMVLAILAFLRFTAIKPSLGLINRWGSVGKKEAMEIIKKFKKDLAAMLRIINARKEKK RRGADTSVGIVGLLLTTAMAAEVTRRGSAYYMYLDRNDAGEAISFPTTLGMNKCYIQI MDLGHMCDATMSYECPMLDEGVEPDDVDCWCNTTSTWVVYGTCHHKKGEARRSRRAVT LPSHSTRKLQTRSQTWLESREYTKHLIRVENWIFRNPGFALAAAAIAWLLGSSTSQKV IYLVMILLIAPAYSIRCIGVSNRDFVEGMSGGTWVDVVLEHGGCVTVMAQDKPTVDIE LVTTTVSNMAEVRSYCYEASISDMASDSRCPTQGEAYLDKQSDTQYVCKRTLVDRGWG NGCGLFGKGSLVTCAKFACSKKMTGKSIQPENLEYRIMLSVHGSQHSGMIVNDTGHET DENRAKVEITPNSPRAEATLGGFGSLGLDCEPRTGLDFSDLYYLTMNNKHWLVHKEWF HDIPLPWHAGADTGTPHWNNKEALVEFKDAHAKRQTVVVLGSQEGAVHTALAGALEAE MDGAKGRLSSGHLKCRLKMDKLRLKGVSYSLCTAAFTFTKIPAETLHGTVTVEVQYAG TDGPCKVPAQMAVDMQTLTPVGRLITANPVITESTENSKMMLELDPPFGDSYIVIGVG EKKITHHWHRSGSTIGKAFEATVRGAKRMAVLGDTAWDFGSVGGALNSLGKGIHQIFG AAFKSLFGGMSWFSQILIGTLLMWLGLNTKNGSISLMCLALGGVLIFLSTAVSADVGC SVDFSKKETRCGTGVFVYNDVEAWRDRYKYHPDSPRRLAAAVKQAWEDGICGISSVSR MENIMWRSVEGELNAILEENGVQLTVVVGSVKNPMWRGPQRLPVPVNELPHGWKAWGK SYFVRAAKTNNSFVVDGDTLKECPLKHRAWNSFLVEDHGFGVFHTSVWLKVREDYSLE CDPAVIGTAVKGKEAVHSDLGYWIESEKNDTWRLKRAHLIEMKTCEWPKSHTLWTDGI EESDLIIPKSLAGPLSHHNTREGYRTQMKGPWHSEELEIRFEECPGTKVHVEETCGTR GPSLRSTTASGRVIEEWCCRECTMPPLSFRAKDGCWYGMEIRPRKEPESNLVRSVVTA GSTDHMDHFSLGVLVILLMVQEGLKKRMTTKIIISTSMAVLVAMILGGFSMSDLAKLA ILMGATFAEMNTGGDVAHLALIAAFKVRPALLVSFIFRANWTPRESMLLALASCLLQT AISALEGDLMVLINGFALAWLAIRAMVVPRTDNITLAILAALTPLARGTLLVAWRAGL ATCGGFMLLSLKGKGSVKKNLPFVMALGLTAVRLVDPINVVGLLLLTRSGKRSWPPSE VLTAVGLICALAGGFAKADIEMAGPMAAVGLLIVSYVVSGKSVDMYIERAGDITWEKD AEVTGNSPRLDVALDESGDFSLVEDDGPPMREIILKVVLMTICGMNPIAIPFAAGAWY VYVKTGKRSGALWDVPAPKEVKKGETTDGVYRVMTRRLLGSTQVGVGVMQEGVFHTMW HVTKGSALRSGEGRLDPYWGDVKQDLVSYCGPWKLDAAWDGHSEVQLLAVPPGERARN IQTLPGIFKTKDGDIGAVALDYPAGTSGSPILDKCGRVIGLYGNGVVIKNGSYVSAIT QGRREEETPVECFEPSMLKKKQLTVLDLHPGAGKTRRVLPEIVREAIKTRLRTVILAP TRVVAAEMEEALRGLPVRYMTTAVNVTHSGTEIVDLMCHATFTSRLLQPIRVPNYNLY IMDEAHFTDPSSIAARGYISTRVEMGEAAAIFMTATPPGTRDAFPDSNSPIMDTEVEV PERAWSSGFDWVTDHSGKTVWFVPSVRNGNEIAACLTKAGKRVIQLSRKTFETEFQKT KHQEWDFVVTTDISEMGANFKADRVIDSRRCLKPVILDGERVILAGPMPVTHASAAQR RGRIGRNPNKPGDEYLYGGGCAETDEDHAHWLEARMLLDNIYLQDGLIASLYRPEADK VAAIEGEFKLRTEQRKTFVELMKRGDLPVWLAYQVASAGITYTDRRWCFDGTTNNTIM EDSVPAEVWTRHGEKRVLKPRWMDARVCSDHAALKSFKEFAAGKRGAAFGVMEALGTL PGHMTERFQEAIDNLAVLMRAETGSRPYKAAAAQLPETLETIMLLGLLGTVSLGIFFV LMRNKGIGKMGFGMVTLGASAWLMWLSEIEPARIACVLIVVFLLLVVLIPEPEKQRSP QDNQMAIIIMVAVGLLGLITANELGWLERTKSDLSHLMGRREEGATIGFSMDIDLRPA SAWAIYAALTTFITPAVQHAVTTSYNNYSLMAMATQAGVLFGMGKGMPFYAWDFGVPL LMIGCYSQLTPLTLIVAIILLVAHYMYLIPGLQAAAARAAQKRTAAGIMKNPVVDGIV VTDIDTMTIDPQVEKKMGQVLLIAVAVSSAILSRTAWGWGEAGALITAATSTLWEGSP NKYWNSSTATSLCNIFRGSYLAGASLIYTVTRNAGLVKRRGGGTGETLGEKWKARLNQ MSALEFYSYKKSGITEVCREEARRALKDGVATGGHAVSRGSAKLRWLVERGYLQPYGK VIDLGCGRGGWSYYAATIRKVQEVKGYTKGGPGHEEPVLVQSYGWNIVRLKSGVDVFH MAAEPCDTLLCDIGESSSSPEVEEARTLRVLSMVGDWLEKRPGAFCIKVLCPYTSTMM ETLERLQRRYGGGLVRVPLSRNSTHEMYWVSGAKSNTIKSVSTTSQLLLGRMDGPRRP VKYEEDVNLGSGTRAVVSCAEAPNMKIIGNRIERIRSEHAETWFFDENHPYRTWAYHG SYEAPTQGSASSLVNGVVRLLSKPWDVVTGVTGIAMTDTTPYGQQRVFKEKVDTRVPD PQEGTRQVMSMVSSWLWKELGKHKRPRVCTKEEFINKVRSNAALGAIFEEEKEWKTAV EAVNDPRFWALVDKEREHHLRGECQSCVYNMMGKREKKQGEFGKAKGSRAIWYMWLGA RFLEFEALGFLNEDHWMGRENSGGGVEGLGLQRLGYVLEEMSRIPGGRMYADDTAGWD TRISRFDLENEALITNQMEKGHRALALAIIKYTYQNKVVKVLRPAEKGKTVMDIISRQ DQRGSGQVVTYALNTFTNLVVQLIRNMEAEEVLEMQDLWLLRRSEKVTNWLQSNGWDR LKRMAVSGDDCVVKPIDDRFAHALRFLNDMGKVRKDTQEWKPSTGWDNWEEVPFCSHH FNKLHLKDGRSIVVPCRHQDELIGRARVSPGAGWSIRETACLAKSYAQMWQLLYFHRR DLRLMANAICSSVPVDWVPTGRTTWSIHGKGEWMTIEDMLVVWNRVWIEENDHMEDKT PVTKWTDIPYLGKREDLWCGSLIGHRPRTTWAENIKNTVNMVRRIIGEEEKYMDYLST QVRYLGEEGSTPGVL" ORIGIN 1 cgacagttcg agtttgaagc gaaagctagc aacagtatca acaggtttta ttttggattt 61 ggaaacgaga gtttctggtc atgaaaaacc caaaaaagaa atccggagga ttccggattg 121 tcaatatgct aaaacgcgga gtagcccgtg tgagcccctt tgggggcttg aagaggctgc 181 cagccggact tctgctgggt catgggccca tcaggatggt cttggcgatt ctagcctttt 241 tgagattcac ggcaatcaag ccatcactgg gtctcatcaa tagatggggt tcagtgggga 301 aaaaagaggc tatggaaata ataaagaagt tcaagaaaga tctggctgcc atgctgagaa 361 taatcaatgc taggaaggag aagaagagac gaggcgcaga tactagtgtc ggaattgttg 421 gcctcctgct gaccacagct atggcagcgg aggtcactag acgtgggagt gcatactaca 481 tgtacttgga cagaaacgat gctggggagg ccatatcttt tccaaccaca ttggggatga 541 ataagtgtta tatacagatc atggatcttg gacacatgtg tgatgccacc atgagctatg 601 aatgccctat gctggatgag ggggtggaac cagatgacgt cgattgttgg tgcaacacga 661 cgtcaacttg ggttgtgtac ggaacctgcc atcacaaaaa aggtgaagca cggagatcta 721 gaagagctgt gacgctcccc tcccattcca ctaggaagct gcaaacgcgg tcgcaaacct 781 ggttggaatc aagagaatac acaaagcact tgattagagt cgaaaattgg atattcagga 841 accctggctt cgcgttagca gcagctgcca tcgcttggct tttgggaagc tcaacgagcc 901 aaaaagtcat atacttggtc atgatactgc tgattgcccc ggcatacagc atcaggtgca 961 taggagtcag caatagggac tttgtggaag gtatgtcagg tgggacttgg gttgatgttg 1021 tcttggaaca tggaggttgt gtcaccgtaa tggcacagga caaaccgact gtcgacatag 1081 agctggttac aacaacagtc agcaacatgg cggaggtaag atcctactgc tatgaggcat 1141 caatatcaga catggcttcg gacagccgct gcccaacaca aggtgaagcc taccttgaca 1201 agcaatcaga cactcaatat gtctgcaaaa gaacgttagt ggacagaggc tggggaaatg 1261 gatgtggact ttttggcaaa gggagcctgg tgacatgcgc taagtttgca tgctccaaga 1321 aaatgaccgg gaagagcatc cagccagaga atctggagta ccggataatg ctgtcagttc 1381 atggctccca gcacagtggg atgatcgtta atgacacagg acatgaaact gatgagaata 1441 gagcgaaggt tgagataacg cccaattcac caagagccga agccaccctg gggggttttg 1501 gaagcctagg acttgattgt gaaccgagga caggccttga cttctcagat ttgtattact 1561 tgactatgaa taacaagcac tggttggttc acaaggagtg gttccacgac attccattac 1621 cttggcacgc tggggcagac accggaactc cacactggaa caacaaagaa gcactggtag 1681 agttcaagga cgcacatgcc aaaaggcaaa ctgtcgtggt tctagggagt caagaaggag 1741 cagttcacac ggcccttgct ggagctctgg aggctgagat ggatggtgca aagggaaggc 1801 tgtcctctgg ccacttgaaa tgtcgcctga aaatggataa acttagattg aagggcgtgt 1861 catactcctt gtgtaccgca gcgttcacat tcaccaagat cccggctgaa acactgcacg 1921 ggacagtcac agtggaggta cagtacgcag ggacagatgg accttgcaag gttccagctc 1981 agatggcggt ggacatgcaa actctgaccc cagttgggag gttgataacc gccaaccccg 2041 taatcactga aagcactgag aactctaaga tgatgctgga acttgatcca ccatttgggg 2101 actcttacat tgtcatagga gtcggggaga agaagatcac ccaccactgg cacaggagtg 2161 gcagcaccat tggaaaagca tttgaagcca ctgtgagagg tgccaagaga atggcagtct 2221 tgggagacac agcctgggac tttggatcag ttggaggcgc tctcaactca ttgggcaagg 2281 gcatccatca aatttttgga gcagctttca aatcattgtt tggaggaatg tcctggttct 2341 cacaaatcct cattggaacg ttgctgatgt ggttgggtct aaacacaaag aatggatcta 2401 tttccctcat gtgcttggcc ttagggggag tgctgatctt cttatccaca gccgtctctg 2461 ctgatgtggg gtgctcggtg gacttctcaa agaaggagac gagatgcggt acaggggtgt 2521 tcgtctataa cgacgttgaa gcctggaggg acaggtacaa gtaccatcct gactcccccc 2581 gtagattggc agcagcagtc aagcaagcct gggaagatgg tatctgcggg atctcctctg 2641 tttcaagaat ggaaaacatc atgtggagat cagtagaagg ggagctcaat gcaatcctgg 2701 aagagaatgg agttcaactg acggtcgttg tgggatctgt aaaaaacccc atgtggagag 2761 gtccacagag attgcccgtg cctgtgaacg agctgcccca cggctggaag gcttggggga 2821 aatcgtactt cgttagagca gcaaagacaa ataacagctt tgtcgtggat ggtgacacac 2881 tgaaggaatg cccactcaaa catagagcat ggaacagctt tcttgtggag gatcatgggt 2941 tcggggtatt ccacactagt gtctggctca aggttagaga agattattca ttagagtgtg 3001 atccagccgt tattggaaca gctgttaagg gaaaggaggc tgtacacagt gatctaggct 3061 actggattga gagtgagaag aatgacacat ggaggctgaa gagggcccat ctgatcgaga 3121 tgaaaacatg tgaatggcca aagtcccaca cattgtggac agatggaata gaagagagtg 3181 atctgatcat acccaagtct ttagctgggc cactcagcca tcacaatacc agagagggct 3241 acaggaccca aatgaaaggg ccatggcaca gtgaagagct tgaaattcgg tttgaggaat 3301 gcccaggcac taaggtccac gtggaggaaa catgtggaac aagaggacca tctctgagat 3361 caaccactgc aagcggaagg gtgatcgagg aatggtgctg cagggagtgc acaatgcccc 3421 cactgtcgtt ccgggctaaa gatggctgtt ggtatggaat ggagataagg cccaggaaag 3481 aaccagaaag caacttagta aggtcagtgg tgactgcagg atcaactgat cacatggatc 3541 acttctccct tggagtgctt gtgattctgc tcatggtgca ggaagggctg aagaagagaa 3601 tgaccacaaa gatcatcata agcacatcaa tggcagtgct ggtagctatg atcctgggag 3661 gattttcaat gagtgacctg gctaagcttg caatcttgat gggtgccacc ttcgcggaaa 3721 tgaacactgg aggagatgta gctcatctgg cgctgatagc ggcattcaaa gtcagaccag 3781 cgttgctggt atctttcatc ttcagagcta attggacacc ccgtgaaagc atgctgctgg 3841 ccttggcctc gtgtcttttg caaactgcga tctccgcctt ggaaggcgac ctgatggttc 3901 tcatcaatgg ttttgctttg gcctggttgg caatacgagc gatggttgtt ccacgcactg 3961 ataacatcac cttggcaatc ctggctgctc tgacaccact ggcccggggc acactgcttg 4021 tggcgtggag agcaggcctt gctacttgcg gggggtttat gctcctctct ctgaagggaa 4081 aaggcagtgt gaagaagaac ttaccatttg tcatggccct gggactaacc gctgtgagac 4141 tggtcgaccc catcaacgtg gtgggactgc tgttgctcac aaggagtggg aagcggagct 4201 ggccccctag cgaagtactc acagctgttg gcctgatatg cgcattggct ggagggttcg 4261 ccaaggcaga tatagagatg gctgggccca tggccgcggt cggtctgcta attgtcagtt 4321 acgtggtctc aggaaagagt gtggacatgt acattgaaag agcaggtgac atcacatggg 4381 aaaaagatgc ggaagtcact ggaaacagtc cccggctcga tgtggcgcta gatgagagtg 4441 gtgatttctc cctggtggag gatgacggtc cccccatgag agagatcata ctcaaggtgg 4501 tcctgatgac catctgtggc atgaacccaa tagccatacc ctttgcagct ggagcgtggt 4561 acgtatacgt gaagactgga aaaaggagtg gtgctctatg ggatgtgcct gctcccaagg 4621 aagtaaaaaa gggggagacc acagatggag tgtacagagt aatgactcgt agactgctag 4681 gttcaacaca agttggagtg ggagttatgc aagagggggt ctttcacact atgtggcacg 4741 tcacaaaagg atccgcgctg agaagcggtg aagggagact tgatccatac tggggagatg 4801 tcaagcagga tctggtgtca tactgtggtc catggaagct agatgccgcc tgggacgggc 4861 acagcgaggt gcagctcttg gccgtgcccc ccggagagag agcgaggaac atccagactc 4921 tgcccggaat atttaagaca aaggatgggg acattggagc ggttgcgctg gattacccag 4981 caggaacttc aggatctcca atcctagaca agtgtgggag agtgatagga ctttatggca 5041 atggggtcgt gatcaaaaat gggagttatg ttagtgccat cacccaaggg aggagggagg 5101 aagagactcc tgttgagtgc ttcgagcctt cgatgctgaa gaagaagcag ctaactgtct 5161 tagacttgca ccctggagct gggaaaacca ggagagttct tcctgaaata gtccgtgaag 5221 ctataaaaac aagactccgt actgtgatct tagctccaac cagggttgtc gctgctgaaa 5281 tggaggaagc ccttagaggg cttccagtgc gttatatgac aacagcagtc aatgtcaccc 5341 attctggaac agaaatcgtc gacttaatgt gccatgccac cttcacttca cgtctactac 5401 agccaatcag agtccccaac tataatctgt atattatgga tgaggcccac ttcacagatc 5461 cctcaagtat agcagcaaga ggatacattt caacaagggt tgagatgggc gaggcggctg 5521 ccatcttcat gaccgccacg ccaccaggaa cccgtgacgc atttccggac tccaactcac 5581 caattatgga caccgaagtg gaagtcccgg agagagcctg gagctcaggc tttgattggg 5641 tgacggatca ttctggaaaa acagtttggt ttgttccaag cgtgaggaac ggcaatgaga 5701 tcgcagcttg tctgacaaag gctggaaaac gggtcataca gctcagcaga aagacttttg 5761 agacagagtt ccagaaaaca aaacatcaag agtgggactt tgtcgtgaca accgacattt 5821 cagagatggg cgccaacttt aaagctgacc gtgtcataga ttccaggaga tgcctaaagc 5881 cggtcatact tgatggcgag agagtcattc tggctggacc catgcctgtc acacatgcca 5941 gcgctgccca gaggaggggg cgcataggca ggaatcccaa caaacctgga gatgagtatc 6001 tgtatggagg tgggtgcgca gagactgacg aagaccatgc acactggctt gaagcaagaa 6061 tgctccttga caatatttac ctccaagatg gcctcatagc ctcgctctat cgacctgagg 6121 ctgacaaagt agcagccatt gagggagagt tcaagcttag gacggagcaa aggaagacct 6181 ttgtggaact catgaaaaga ggagatcttc ctgtttggct ggcctatcag gttgcatctg 6241 ccggaataac ttacacagat agaagatggt gctttgatgg cacgaccaac aacaccataa 6301 tggaagacag tgtgccggca gaggtgtgga ccagacacgg agagaaaaga gtgctcaaac 6361 cgaggtggat ggacgccaga gtttgttcag atcatgcggc cctgaagtca ttcaaggagt 6421 ttgccgctgg gaaaagagga gcggcttttg gagtgatgga agccctggga acactgccag 6481 gacacatgac agagagattc caggaagcca ttgacaacct cgctgtgctc atgcgggcag 6541 agactggaag caggccttac aaagccgcgg cggcccaatt gccggagacc ctagagacca 6601 ttatgctttt ggggttgctg ggaacagtct cgctgggaat ctttttcgtc ttgatgagga 6661 acaagggcat agggaagatg ggctttggaa tggtgactct tggggccagc gcatggctca 6721 tgtggctctc ggaaattgag ccagccagaa ttgcatgtgt cctcattgtt gtgttcctat 6781 tgctggtggt gctcatacct gagccagaaa agcaaagatc tccccaggac aaccaaatgg 6841 caatcatcat catggtagca gtaggtcttc tgggcttgat caccgccaat gaactcggat 6901 ggttggagag aacaaagagt gacctaagcc atctaatggg aaggagagag gagggagcaa 6961 ccataggatt ctcaatggac attgacctgc ggccagcctc agcttgggcc atctatgctg 7021 ccttgacaac tttcattacc ccagccgtcc aacatgcagt gaccacttca tacaacaact 7081 actccttaat ggcgatggcc acgcaagctg gagtgttgtt tggtatgggc aaagggatgc 7141 cattctacgc atgggacttt ggagtcccgc tgctaatgat aggttgctac tcacaattaa 7201 cacccctgac cctaatagtg gccatcattt tgctcgtggc gcactacatg tacttgatcc 7261 cagggctgca ggcagcagct gcgcgtgctg cccagaagag aacggcagct ggcatcatga 7321 agaaccctgt tgtggatgga atagtggtga ctgacattga cacaatgaca attgaccccc 7381 aagtggagaa aaagatggga caggtgctac tcatagcagt agccgtctcc agcgccatac 7441 tgtcgcggac cgcctggggg tggggggagg ctggggccct gatcacagcc gcaacttcca 7501 ctttgtggga aggctctccg aacaagtact ggaactcctc tacagccact tcactgtgta 7561 acatttttag ggggagttac ttggctggag cttctctaat ctacacagta acaagaaacg 7621 ctggcttggt caagagacgt gggggtggaa caggagagac cctgggagag aaatggaagg 7681 cccgcttgaa ccagatgtcg gccctggagt tctactccta caaaaagtca ggcatcaccg 7741 aggtgtgcag agaagaggcc cgccgcgccc tcaaggacgg tgtggcaacg ggaggccatg 7801 ctgtgtcccg aggaagtgca aagctgagat ggttggtgga gcggggatac ctgcagccct 7861 atggaaaggt cattgatctt ggatgtggca gagggggctg gagttactac gccgccacca 7921 tccgcaaagt tcaagaagtg aaaggataca caaaaggagg ccctggtcat gaagaacctg 7981 tgttggtgca aagctatggg tggaacatag tccgtctcaa gagtggggtg gacgtctttc 8041 atatggcggc tgagccgtgt gacacgttgc tgtgtgacat aggtgagtca tcatctagtc 8101 ctgaagtgga agaagcacgg acgctcagag tcctctccat ggtgggggat tggcttgaaa 8161 aaagaccagg agccttttgt ataaaagtgt tgtgcccata caccagcact atgatggaaa 8221 ccttggagcg gctgcagcgt aggtatgggg gaggactggt cagagtgcca ctctcccgca 8281 actctacaca tgagatgtac tgggtctctg gagcgaaaag caacaccata aaaagtgtgt 8341 ccaccacgag ccagctcctc ttggggcgca tggacgggcc taggaggcca gtgaaatatg 8401 aggaggatgt gaatctcggc tctggcacgc gggctgtggt aagctgcgct gaagctccca 8461 acatgaagat cattggtaac cgcattgaaa ggatccgcag tgagcacgcg gaaacgtggt 8521 tctttgacga gaaccaccca tataggacat gggcttacca tggaagctat gaggccccta 8581 cacaagggtc agcatcctct ctagtaaacg gggttgtcag gctcctgtca aaaccctggg 8641 atgtggtgac tggagtcaca ggaatagcca tgaccgacac cacaccgtat ggtcagcaaa 8701 gagttttcaa ggaaaaagtg gacactaggg tgccagaccc ccaagaaggc actcgtcagg 8761 ttatgagcat ggtctcttcc tggttgtgga aagagctagg caaacacaaa cggccacgag 8821 tctgcaccaa agaagagttc atcaacaagg ttcgtagcaa tgcagcatta ggggcaatat 8881 ttgaagagga aaaagagtgg aagactgcag tggaagctgt gaacgatcca aggttctggg 8941 ctctagtgga caaggaaaga gagcaccacc tgagaggaga gtgccagagt tgtgtgtaca 9001 acatgatggg aaaaagagaa aagaaacaag gggaatttgg aaaggccaag ggcagccgcg 9061 ccatctggta tatgtggcta ggggctagat ttctagagtt cgaagccctt ggattcttga 9121 acgaggatca ctggatgggg agagagaact caggaggtgg tgttgaaggg ctgggattac 9181 aaagactcgg atatgtccta gaagagatga gtcgcatacc aggaggaagg atgtatgcag 9241 atgacactgc tggctgggat acccgcatca gcaggtttga tctagagaat gaagctctaa 9301 tcaccaacca aatggagaaa gggcacaggg ccttggcatt ggccataatc aagtacacat 9361 accaaaataa agtggtaaag gtccttagac cagctgaaaa agggaaaaca gttatggaca 9421 ttatttcgag acaagaccaa agggggagcg gacaagttgt cacttacgct cttaacacat 9481 ttaccaacct agtggtgcaa ctcattcgga atatggaggc tgaggaagtt ctagagatgc 9541 aagacttgtg gctgctgcgg aggtcagaga aagtgaccaa ctggttgcag agcaacggat 9601 gggataggct caaacgaatg gcagtcagtg gagatgattg cgttgtgaag ccaattgatg 9661 ataggtttgc acatgccctc aggttcttga atgatatggg aaaagttagg aaggacacac 9721 aagagtggaa accctcaact ggatgggaca actgggaaga agttccgttt tgctcccacc 9781 acttcaacaa gctccatctc aaggacggga ggtccattgt ggttccctgc cgccaccaag 9841 atgaactgat tggccgggcc cgcgtctctc caggggcggg atggagcatc cgggagactg 9901 cttgcctagc aaaatcatat gcgcaaatgt ggcagctcct ttatttccac agaagggacc 9961 tccgactgat ggccaatgcc atttgttcat ctgtgccagt tgactgggtt ccaactggga 10021 gaactacctg gtcaatccat ggaaagggag aatggatgac cattgaagac atgcttgtgg 10081 tgtggaacag agtgtggatt gaggagaacg accacatgga agacaagacc ccagttacga 10141 aatggacaga cattccctat ttgggaaaaa gggaagactt gtggtgtgga tctctcatag 10201 ggcacagacc gcgcaccacc tgggctgaga acattaaaaa cacagtcaac atggtgcgca 10261 ggatcatagg tgaggaagaa aagtacatgg actacctatc cacccaagtt cgttacttgg 10321 gtgaagaagg gtctacacct ggagtgctgt aagcaccaat cttaatgttg tcaggcctgc 10381 tagtcagcca cagcttgggg aaagctgtgc agcctgtgac ccccccagga gaagctggga 10441 aaccaagcct atagtcaggc cgagaacgcc atggcacgga agaagccatg ctgcctgtga 10501 gcccctcaga ggacactgag tcaaaaaacc ccacgcgctt ggaggcgcag gatgggaaaa 10561 gaaggtggcg accttcccca cccttcaatc tggggcctga actgga

Sequences producing significant alignments: Select:AllNone Selected:0 AlignmentsDownloadGenBankGraphicsDistance tree of resultsShow/hide columns of the table presenting sequences producing significant alignments Sequences producing significant alignments: Select for downloading or viewing reports Description Max score Total score Query cover E value Ident Accession Select seq gb|KU853013.1| Zika virus isolate Dominican Republic/2016/PD2, complete genome 18465 18465 100% 0.0 99% KU853013.1 Select seq gb|KU853012.1| Zika virus isolate Dominican Republic/2016/PD1, complete genome 18465 18465 100% 0.0 99% KU853012.1 Select seq gb|KX842449.1| Zika virus isolate ZIKV/Human/USA/2016/ZF10.UR-010 polyprotein gene, complete cds 18429 18429 100% 0.0 99% KX842449.1 Select seq gb|KX838905.1| Zika virus isolate ZIKV/Aedes_aegypti/USA/2016/ZM2-7719 polyprotein gene, complete cds 18426 18426 100% 0.0 99% KX838905.1 Select seq gb|KX838904.1| Zika virus isolate ZIKV/Aedes_aegypti/USA/2016/ZM1-7501 polyprotein gene, complete cds 18420 18420 100% 0.0 99% KX838904.1 Select seq gb|KX832731.1| Zika virus isolate ZIKV/Human/USA/2016/ZL2.SA-Hu0015 polyprotein gene, complete cds 18420 18420 100% 0.0 99% KX832731.1 Select seq gb|KX673530.1| Zika virus isolate PHE_semen_Guadeloupe, complete genome 18417 18417 100% 0.0 99% KX673530.1 Select seq gb|KX838906.1| Zika virus isolate ZIKV/Aedes_aegypti/USA/2016/ZM3-7729 polyprotein gene, complete cds 18408 18408 100% 0.0 99% KX838906.1 Select seq gb|KX447510.1| Zika virus isolate 1_0049_PF polyprotein gene, complete cds 18357 18357 100% 0.0 99% KX447510.1 Select seq gb|KX280026.1| Zika virus isolate Paraiba_01, complete genome 18354 18354 100% 0.0 99% KX280026.1 Select seq gb|KX447512.1| Zika virus isolate 1_0181_PF polyprotein gene, complete cds 18348 18348 100% 0.0 99% KX447512.1 Select seq gb|KX369547.1| Zika virus strain PF13/251013-18, complete genome 18348 18348 100% 0.0 99% KX369547.1 Select seq gb|KU509998.3| Zika virus strain Haiti/1225/2014, complete genome 18348 18348 100% 0.0 99% KU509998.3 Select seq gb|KJ776791.2| Zika virus strain H/PF/2013, complete genome 18345 18345 100% 0.0 99% KJ776791.2 Select seq gb|KX447509.1| Zika virus isolate 1_0087_PF polyprotein gene, complete cds 18345 18345 100% 0.0 99% KX447509.1 Select seq gb|KU991811.1| Zika virus isolate Brazil/2016/INMI1 polyprotein gene, complete cds 18345 18345 100% 0.0 99% KU991811.1 Select seq gb|KU729217.2| Zika virus isolate BeH823339 polyprotein gene, complete cds 18345 18345 100% 0.0 99% KU729217.2 Select seq gb|KX447513.1| Zika virus isolate 1_0134_PF polyprotein gene, complete cds 18339 18339 100% 0.0 99% KX447513.1 Select seq gb|KX811222.1| Zika virus isolate Brazil_2015_MG, complete genome 18336 18336 100% 0.0 99% KX811222.1 Select seq gb|KX197205.1| Zika virus isolate 9, complete genome 18336 18336 100% 0.0 99% KX197205.1 Select seq gb|KX447515.1| Zika virus isolate 1_0030_PF polyprotein gene, complete cds 18336 18336 100% 0.0 99% KX447515.1 Select seq gb|KX447511.1| Zika virus isolate 1_0015_PF polyprotein gene, complete cds 18336 18336 100% 0.0 99% KX447511.1 Select seq gb|KU321639.1| Zika virus strain ZikaSPH2015, complete genome 18336 18336 100% 0.0 99% KU321639.1 Select seq gb|KX879604.1| Zika virus isolate SN089, complete genome 18330 18330 100% 0.0 99% KX879604.1 Select seq gb|KX447514.1| Zika virus isolate 1_0035_PF polyprotein gene, complete cds 18330 18330 100% 0.0 99% KX447514.1 Select seq gb|KX051563.1| Zika virus isolate Haiti/1/2016, complete genome 18330 18330 100% 0.0 99% KX051563.1 Select seq gb|KX447516.1| Zika virus isolate 1_0111_PF polyprotein gene, complete cds 18327 18327 100% 0.0 99% KX447516.1 Select seq gb|KU729218.1| Zika virus isolate BeH828305 polyprotein gene, complete cds 18327 18327 100% 0.0 99% KU729218.1 Select seq gb|KU707826.1| Zika virus isolate SSABR1, complete genome 18327 18327 100% 0.0 99% KU707826.1 Select seq gb|KU527068.1| Zika virus strain Natal RGN, complete genome 18327 18327 100% 0.0 99% KU527068.1 Select seq gb|KU365779.1| Zika virus strain BeH819966 polyprotein gene, complete cds 18327 18327 100% 0.0 99% KU365779.1 Select seq gb|KX879603.1| Zika virus isolate SN062, complete genome 18321 18321 100% 0.0 99% KX879603.1 Select seq gb|KX262887.1| Zika virus isolate 103451, complete genome 18321 18321 100% 0.0 99% KX262887.1 Select seq gb|KX197192.1| Zika virus isolate ZIKV/H.sapiens/Brazil/PE243/2015, complete genome 18321 18321 100% 0.0 99% KX197192.1 Select seq gb|KU926310.1| Zika virus isolate Rio-S1, complete genome 18321 18321 100% 0.0 99% KU926310.1 Select seq gb|KU926309.1| Zika virus isolate Rio-U1, complete genome 18321 18321 100% 0.0 99% KU926309.1 Select seq gb|KU501217.1| Zika virus strain 8375 polyprotein gene, complete cds 18321 18321 100% 0.0 99% KU501217.1 Select seq gb|KU940228.1| Zika virus isolate Bahia07, partial genome 18318 18318 100% 0.0 99% KU940228.1 Select seq gb|KU501216.1| Zika virus strain 103344 polyprotein gene, complete cds 18318 18318 100% 0.0 99% KU501216.1 Select seq gb|KX694534.1| Zika virus strain ZIKV/Homo sapiens/HND/R103451/2015, complete genome 18312 18312 100% 0.0 99% KX694534.1 Select seq gb|KX198135.1| Zika virus strain ZIKV/Homo sapiens/PAN/BEI-259634_V4/2016, complete genome 18312 18312 100% 0.0 99% KX198135.1 Select seq gb|KU365780.1| Zika virus strain BeH815744 polyprotein gene, complete cds 18312 18312 100% 0.0 99% KU365780.1 Select seq gb|KU647676.1| Zika virus strain MRS_OPY_Martinique_PaRi_2015 polyprotein gene, complete cds 18309 18309 100% 0.0 99% KU647676.1 Select seq gb|KU365777.1| Zika virus strain BeH818995 polyprotein gene, complete cds 18309 18309 100% 0.0 99% KU365777.1 Select seq gb|KX447517.1| Zika virus isolate 1_0038_PF polyprotein gene, complete cds 18303 18303 100% 0.0 99% KX447517.1 Select seq gb|KU758877.1| Zika virus isolate 17271 polyprotein gene, complete cds 18303 18303 100% 0.0 99% KU758877.1 Select seq gb|KX247646.1| Zika virus isolate Zika virus/Homo sapiens/COL/UF-1/2016, complete genome 18303 18303 100% 0.0 99% KX247646.1 Select seq gb|KX156776.1| Zika virus strain ZIKV/Homo sapiens/PAN/CDC-259364_V1-V2/2015, complete genome 18303 18303 100% 0.0 99% KX156776.1 Select seq gb|KX520666.1| Zika virus isolate HS-2015-BA-01 polyprotein gene, complete cds 18300 18300 100% 0.0 99% KX520666.1 Select seq gb|KX156774.1| Zika virus strain ZIKV/Homo sapiens/PAN/CDC-259359_V1-V3/2015, complete genome 18300 18300 100% 0.0 99% KX156774.1 Select seq gb|KU497555.1| Zika virus isolate Brazil-ZKV2015, complete genome 18300 18300 99% 0.0 99% KU497555.1 Select seq gb|KU820897.5| Zika virus isolate FLR polyprotein gene, complete cds 18294 18294 100% 0.0 99% KU820897.5 Select seq gb|KX247632.1| Zika virus isolate MEX_I_7 polyprotein gene, complete cds 18294 18294 100% 0.0 99% KX247632.1 Select seq gb|KX156775.1| Zika virus strain ZIKV/Homo sapiens/PAN/CDC-259249_V1-V3/2015, complete genome 18294 18294 100% 0.0 99% KX156775.1 Select seq gb|KX087102.1| Zika virus strain ZIKV/Homo sapiens/COL/FLR/2015, complete genome 18294 18294 100% 0.0 99% KX087102.1 Select seq gb|KU365778.1| Zika virus strain BeH819015 polyprotein gene, complete cds 18294 18294 100% 0.0 99% KU365778.1 Select seq gb|KU312312.1| Zika virus isolate Z1106033 polyprotein gene, complete cds 18294 18294 100% 0.0 99% KU312312.1 Select seq gb|KU922960.1| Zika virus isolate MEX/InDRE/Sm/2016, complete genome 18291 18291 100% 0.0 99% KU922960.1 Select seq gb|KX856011.1| Zika virus strain ZIKV/Aedes sp./MEX_I-44/2016, complete genome 18285 18285 100% 0.0 99% KX856011.1 Select seq gb|KX806557.1| Zika virus isolate TS17-2016, complete genome 18285 18285 100% 0.0 99% KX806557.1 Select seq gb|KX548902.1| Zika virus isolate ZIKV/COL/FCC00093/2015 polyprotein gene, complete cds 18285 18285 100% 0.0 99% KX548902.1 Select seq gb|KX446951.1| Zika virus strain ZIKV/Aedes.sp/MEX/MEX_I-7/2016, complete genome 18285 18285 100% 0.0 99% KX446951.1 Select seq gb|KU937936.1| Zika virus isolate ZIKVNL00013 polyprotein gene, complete cds 18285 18285 100% 0.0 99% KU937936.1 Select seq gb|KU922923.1| Zika virus isolate MEX/InDRE/Lm/2016, complete genome 18285 18285 100% 0.0 99% KU922923.1 Select seq gb|KU501215.1| Zika virus strain PRVABC59, complete genome 18285 18285 100% 0.0 99% KU501215.1 Select seq gb|KX601168.1| Zika virus strain ZIKV/Homo Sapiens/PRI/PRVABC59/2015, complete genome 18282 18282 100% 0.0 99% KX601168.1 Select seq gb|KX446950.1| Zika virus strain ZIKV/Aedes.sp/MEX/MEX_2-81/2016, complete genome 18282 18282 100% 0.0 99% KX446950.1 Select seq gb|KX087101.2| Zika virus strain ZIKV/Homo sapiens/PRI/PRVABC59/2015, complete genome 18282 18282 100% 0.0 99% KX087101.2 Select seq gb|KU870645.1| Zika virus isolate FB-GWUH-2016, complete genome 18282 18282 100% 0.0 99% KU870645.1 Select seq gb|KX702400.1| Zika virus strain Zika virus/Homo sapiens/VEN/UF-1/2016, complete genome 18276 18276 100% 0.0 99% KX702400.1 Select seq gb|KX377337.1| Zika virus strain PRVABC-59, complete genome 18276 18276 100% 0.0 99% KX377337.1 Select seq gb|KX766029.1| Zika virus isolate R116265, complete genome 18267 18267 100% 0.0 99% KX766029.1 Select seq gb|KU820898.1| Zika virus isolate GZ01 polyprotein gene, complete cds 18267 18267 100% 0.0 99% KU820898.1 Select seq gb|KX056898.1| Zika virus isolate Zika virus/GZ02/2016 polyprotein gene, complete cds 18264 18264 100% 0.0 99% KX056898.1 Select seq gb|KU955590.1| Zika virus isolate Z16019 polyprotein gene, complete cds 18264 18264 100% 0.0 99% KU955590.1 Select seq gb|KX766028.1| Zika virus isolate R114916, complete genome 18260 18260 100% 0.0 99% KX766028.1 Select seq gb|KU740184.2| Zika virus isolate GD01 polyprotein gene, complete cds 18258 18258 100% 0.0 99% KU740184.2 Select seq gb|KU761564.1| Zika virus isolate GDZ16001 polyprotein gene, complete cds 18258 18258 100% 0.0 99% KU761564.1 Select seq gb|KX117076.1| Zika virus isolate Zhejiang04, complete genome 18254 18254 100% 0.0 99% KX117076.1 Select seq gb|KX185891.1| Zika virus isolate Zika virus/CN/SZ02/2016 polyprotein gene, complete cds 18245 18245 100% 0.0 99% KX185891.1 Select seq gb|KU963796.1| Zika virus isolate SZ-WIV01 polyprotein gene, complete cds 18245 18245 100% 0.0 99% KU963796.1 Select seq gb|KX253996.1| Zika virus isolate ZKC2/2016, complete genome 18240 18240 100% 0.0 99% KX253996.1 Select seq gb|KU955589.1| Zika virus isolate Z16006 polyprotein gene, complete cds 18240 18240 100% 0.0 99% KU955589.1 Select seq gb|KU820899.2| Zika virus isolate ZJ03, complete genome 18240 18240 100% 0.0 99% KU820899.2 Select seq gb|KX266255.1| Zika virus isolate ZIKV_SMGC-1, complete genome 18236 18236 100% 0.0 99% KX266255.1 Select seq gb|KU866423.2| Zika virus isolate Zika virus/SZ01/2016/China polyprotein gene, complete cds 18236 18236 100% 0.0 99% KU866423.2 Select seq gb|KU940224.1| Zika virus isolate Bahia09, partial genome 18222 18222 99% 0.0 99% KU940224.1 Select seq gb|KU744693.1| Zika virus isolate VE_Ganxian, complete genome 18101 18101 100% 0.0 99% KU744693.1 Select seq gb|KX827309.1| Zika virus isolate ZKA-16-291 polyprotein gene, complete cds 18078 18078 100% 0.0 99% KX827309.1 Select seq gb|KX813683.1| Zika virus isolate ZKA-16-097 polyprotein gene, complete cds 18065 18065 100% 0.0 99% KX813683.1 Select seq gb|KU681081.3| Zika virus isolate Zika virus/H.sapiens-tc/THA/2014/SV0127- 14, complete genome 18011 18011 100% 0.0 99% KU681081.3 Select seq gb|KX694532.1| Zika virus strain ZIKV/Homo sapiens/THA/PLCal_ZV/2013, complete genome 17897 17897 100% 0.0 99% KX694532.1 Select seq gb|KU955593.1| Zika virus isolate Zika virus/H.sapiens-tc/KHM/2010/FSS13025, complete genome 17704 17704 100% 0.0 98% KU955593.1 Select seq gb|JN860885.1| Zika virus isolate FSS13025 polyprotein gene, partial cds 17703 17703 99% 0.0 98% JN860885.1 Select seq gb|KF993678.1| Zika virus strain PLCal_ZV from Canada polyprotein gene, partial cds 17667 17667 98% 0.0 99% KF993678.1 Select seq gb|EU545988.1| Zika virus polyprotein gene, complete cds 17558 17558 100% 0.0 98% EU545988.1 Select seq gb|KU681082.3| Zika virus isolate Zika virus/H.sapiens-tc/PHL/2012/CPC-0740, complete genome 17411 17411 100% 0.0 98% KU681082.3 Select seq gb|KX601167.1| Zika virus strain ZIKV/Aedes sp./MYS/P6-740/1966, complete genome 16401 16401 100% 0.0 95% KX601167.1 Select seq gb|HQ234499.1| Zika virus isolate P6-740 polyprotein gene, partial cds 16393 16393 99% 0.0 95% HQ234499.1 Select seq gb|KX694533.1| Zika virus strain ZIKV/Aedes aegypti/MYS/P6-740/1966, complete genome 16392 16392 100% 0.0 95% KX694533.1

LOCUS KX922707 10609 bp RNA linear VRL 05-OCT-2016 DEFINITION Zika virus isolate ZIKV/Homo_sapiens/USA/2016/FL039U polyprotein gene, complete cds. ACCESSION KX922707 VERSION KX922707.1 GI:1071930518 DBLINK BioProject: PRJNA342539 BioSample: SAMN05853066 KEYWORDS . SOURCE Zika virus ORGANISM Zika virus Viruses; ssRNA viruses; ssRNA positive-strand viruses, no DNA stage; Flaviviridae; Flavivirus. REFERENCE 1 (bases 1 to 10609) AUTHORS Grubaugh,N., Tan,A., Gangavarupu,K., Oliveira,G., Robles-Sikisaka,R., Cone,M., Kopp,E., Hogan,K., Cannons,A., Michael,S., Isern,S. and Andersen,K. TITLE Zika virus sequences from Florida, USA, 2016 JOURNAL Unpublished REFERENCE 2 (bases 1 to 10609) AUTHORS Grubaugh,N., Tan,A., Gangavarupu,K., Oliveira,G., Robles-Sikisaka,R., Cone,M., Kopp,E., Hogan,K., Cannons,A., Michael,S., Isern,S. and Andersen,K. TITLE Direct Submission JOURNAL Submitted (29-SEP-2016) Department of Immunology and Microbial Science, The Scripps Research Institute, 10550 North Torrey Pines Road, IMM-210, La Jolla, CA 92037, USA COMMENT ##Assembly-Data-START## Assembly Method :: NovoAlign v. V3.04 Sequencing Technology :: Illumina ##Assembly-Data-END## FEATURES Location/Qualifiers source 1..10609 /organism="Zika virus" /mol_type="genomic RNA" /isolate="ZIKV/Homo_sapiens/USA/2016/FL039U" /isolation_source="urine" /host="Homo sapiens" /db_xref="taxon:64320" /country="USA: Florida" /collection_date="17-Aug-2016" CDS 81..10352 /codon_start=1 /product="polyprotein" /protein_id="AOS90224.1" /db_xref="GI:1071930519" /translation="MKNPKKKSGGFRIVNMLKRGVARVSPFGGLKRLPAGLLLGHGPI RMVLAILAFLRFTAIKPSLGLINRWGSVGKKEAMEIIKKFKKDLAAMLRIINARKEKK RRGADTSVGIVGLLLTTAMAAEVTRRGSAYYMYLDRNDAGEAISFPTTLGMNKCYIQI MDLGHMCDATMSYECPMLDEGVEPDDVDCWCNTTSTWVVYGTCHHKKGEARRSRRAVT LPSHSTRKLQTRSQTWLESREYTKHLIRVENWIFRNPGFALAAAAIAWLLGSSTSQKV IYLVMILLIAPAYSIRCIGVSNRDFVEGMSGGTWVDVVLEHGGCVTVMAQDKPTVDIE LVTTTVSNMAEVRSYCYEASISDMASDSRCPTQGEAYLDKQSDTQYVCKRTLVDRGWG NGCGLFGKGSLVTCAKFACSKKMTGKSIQPENLEYRIMLSVHGSQHSGMIVNDTGHET DENRAKVEITPNSPRAEATLGGFGSLGLDCEPRTGLDFSDLYYLTMNNKHWLVHKEWF HDIPLPWHAGADTGTPHWNNKEALVEFKDAHAKRQTVVVLGSQEGAVHTALAGALEAE MDGAKGRLSSGHLKCRLKMDKLRLKGVSYSLCTAAFTFTKIPAETLHGTVTVEVQYAG TDGPCKVPAQMAVDMQTLTPVGRLITANPVITESTENSKMMLELDPPFGDSYIVIGVG EKKITHHWHRSGSTIGKAFEATVRGAKRMAVLGDTAWDFGSVGGALNSLGKGIHQIFG AAFKSLFGGMSWFSQILIGTLLMWLGLNTKNGSISLMCLALGGVLIFLSTAVSADVGC SVDFSKKETRCGTGVFVYNDVEAWRDRYKYHPDSPRRLAAAVKQAWEDGICGISSVSR MENIMWRSVEGELNAILEENGVQLTVVVGSVKNPMWRGPQRLPVPVNELPHGWKAWGK SYFVRAAKTNNSFVVDGDTLKECPLKHRAWNSFLVEDHGFGVFHTSVWLKVREDYSLE CDPAVIGTAVKGKEAVHSDLGYWIESEKNDTWRLKRAHLIEMKTCEWPKSHTLWTDGI EESDLIIPKSLAGPLSHHNTREGYRTQMKGPWHSEELEIRFEECPGTKVHVEETCGTR GPSLRSTTASGRVIEEWCCRECTMPPLSFRAKDGCWYGMEIRPRKEPESNLVRSVVTA GSTDHMDHFSLGVLVILLMVQEGLKKRMTTKIIISTSMAVLVAMILGGFSMSDLAKLA ILMGATFAEMNTGGDVAHLALIAAFKVRPALLVSFIFRANWTPRESMLLALASCLLQT AISALEGDLMVLINGFALAWLAIRAMVVPRTDNITLAILAALTPLARGTLLVAWRAGL ATCGGFMLLSLKGKGSVKKNLPFVMALGLTAVRLVDPINVVGLLLLTRSGKRSWPPSE VLTAVGLICALAGGFAKADIEMAGPMAAVGLLIVSYVVSGKSVDMYIERAGDITWEKD AEVTGNSPRLDVALDESGDFSLVEDDGPPMREIILKVVLMTICGMNPIAIPFAAGAWY VYVKTGKRSGALWDVPAPKEVKKGETTDGVYRVMTRRLLGSTQVGVGVMQEGVFHTMW HVTKGSALRSGEGRLDPYWGDVKQDLVSYCGPWKLDAAWDGHSEVQLLAVPPGERARN IQTLPGIFKTKDGDIGAVALDYPAGTSGSPILDKCGRVIGLYGNGVVIKNGSYVSAIT QGRREEETPVECFEPSMLKKKQLTVLDLHPGAGKTRRVLPEIVREAIKTRLRTVILAP TRVVAAEMEEALRGLPVRYMTTAVNVTHSGTEIVDLMCHATFTSRLLQPIRVPNYNLY IMDEAHFTDPSSIAARGYISTRVEMGEAAAIFMTATPPGTRDAFPDSNSPIMDTEVEV PERAWSSGFDWVTDHSGKTVWFVPSVRNGNEIAACLTKAGKRVIQLSRKTFETEFQKT KHQEWDFVVTTDISEMGANFKADRVIDSRRCLKPVILDGERVILAGPMPVTHASAAQR RGRIGRNPNKPGDEYLYGGGCAETDEDHAHWLEARMLLDNIYLQDGLIASLYRPEADK VAAIEGEFKLRTEQRKTFVELMKRGDLPVWLAYQVASAGITYTDRRWCFDGTTNNTIM EDSVPAEVWTRHGEKRVLKPRWMDARVCSDHAALKSFKEFAAGKRGAAFGVMEALGTL PGHMTERFQEAIDNLAVLMRAETGSRPYKAAAAQLPETLETIMLLGLLGTVSLGIFFV LMRNKGIGKMGFGMVTLGASAWLMWLSEIEPARIACVLIVVFLLLVVLIPEPEKQRSP QDNQMAIIIMVAVGLLGLITANELGWLERTKSDLSHLMGRREEGATIGFSMDIDLRPA SAWAIYAALTTFITPAVQHAVTTSYNNYSLMAMATQAGVLFGMGKGMPFYAWDFGVPL LMIGCYSQLTPLTLIVAIILLVAHYMYLIPGLQAAAARAAQKRTAAGIMKNPVVDGIV VTDIDTMTIDPQVEKKMGQVLLIAVAVSSAILSRTAWGWGEAGALITAATSTLWEGSP NKYWNSSTATSLCNIFRGSYLAGASLIYTVTRNAGLVKRRGGGTGETLGEKWKARLNQ MSALEFYSYKKSGITEVCREEARRALKDGVATGGHAVSRGSAKLRWLVERGYLQPYGK VIDLGCGRGGWSYYAATIRKVQEVKGYTKGGPGHEEPVLVQSYGWNIVRLKSGVDVFH MAAEPCDTLLCDIGESSSSPEVEEARTLRVLSMVGDWLEKRPGAFCIKVLCPYTSTMM ETLERLQRRYGGGLVRVPLSRNSTHEMYWVSGAKSNTIKSVSTTSQLLLGRMDGPRRP VKYEEDVNLGSGTRAVVSCAEAPNMKIIGNRIERIRSEHAETWFFDENHPYRTWAYHG SYEAPTQGSASSLVNGVVRLLSKPWDVVTGVTGIAMTDTTPYGQQRVFKEKVDTRVPD PQEGTRQVMSMVSSWLWKELGKHKRPRVCTKEEFINKVRSNAALGAIFEEEKEWKTAV EAVNDPRFWALVDKEREHHLRGECQSCVYNMMGKREKKQGEFGKAKGSRAIWYMWLGA RFLEFEALGFLNEDHWMGRENSGGGVEGLGLQRLGYVLEEMSRIPGGRMYADDTAGWD TRISRFDLENEALITNQMEKGHRALALAIIKYTYQNKVVKVLRPAEKGKTVMDIISRQ DQRGSGQVVTYALNTFTNLVVQLIRNMEAEEVLEMQDLWLLRRSEKVTNWLQSNGWDR LKRMAVSGDDCVVKPIDDRFAHALRFLNDMGKVRKDTQEWKPSTGWDNWEEVPFCSHH FNKLHLKDGRSIVVPCRHQDELIGRARVSPGAGWSIRETACLAKSYAQMWQLLYFHRR DLRLMANAICSSVPVDWVPTGRTTWSIHGKGEWMTTEDMLVVWNRVWIEENDHMEDKT PVTKWTDIPYLGKREDLWCGSLIGHRPRTTWAENIKNTVNMVRRIIGEEEKYMDYLST QVRYLGEEGSTPGVL" ORIGIN 1 cgacagttcg agtttgaagc gaaagctagc aacagtatca acaggtttta ttttggattt 61 ggaaacgaga gtttctggtc atgaaaaacc caaaaaagaa atccggagga ttccggattg 121 tcaatatgct aaaacgcgga gtagcccgtg tgagcccctt tgggggcttg aagaggctgc 181 cagccggact tctgctgggt catgggccca tcaggatggt cttggcgatt ctagcctttt 241 tgagattcac ggcaatcaag ccatcactgg gtctcatcaa tagatggggt tcagtgggga 301 aaaaagaggc tatggaaata ataaagaagt tcaagaaaga tctggctgcc atgctgagaa 361 taatcaatgc taggaaggag aagaagagac gaggcgcaga tactagtgtc ggaattgttg 421 gcctcctgct gaccacagct atggcagcgg aggtcactag acgtgggagt gcatactaca 481 tgtacttgga cagaaacgat gctggggagg ccatatcttt tccaaccaca ttggggatga 541 ataagtgtta tatacagatc atggatcttg gacacatgtg tgatgccacc atgagctatg 601 aatgccctat gctggatgag ggggtggaac cagatgacgt cgattgttgg tgcaacacga 661 cgtcaacttg ggttgtgtac ggaacctgcc atcacaaaaa aggtgaagca cggagatcta 721 gaagagctgt gacgctcccc tcccattcca ctaggaagct gcaaacgcgg tcgcaaacct 781 ggttggaatc aagagaatac acaaagcact tgattagagt cgaaaattgg atattcagga 841 accctggctt cgcgttagca gcagctgcca tcgcttggct tttgggaagc tcaacgagcc 901 aaaaagtcat atacttggtc atgatactgc tgattgcccc ggcatacagc atcaggtgca 961 taggagtcag caatagggac tttgtggaag gtatgtcagg tgggacttgg gttgatgttg 1021 tcttggaaca tggaggttgt gtcaccgtaa tggcacagga caaaccgact gtcgacatag 1081 agctggttac aacaacagtc agcaacatgg cggaggtaag atcctactgc tatgaggcat 1141 caatatcaga catggcttcg gacagccgct gcccaacaca aggtgaagcc taccttgaca 1201 agcaatcaga cactcaatat gtctgcaaaa gaacgttagt ggacagaggc tggggaaatg 1261 gatgtggact ttttggcaaa gggagcctgg tgacatgcgc taagtttgca tgctccaaga 1321 aaatgaccgg gaagagcatc cagccagaga atctggagta ccggataatg ctgtcagttc 1381 atggctccca gcacagtggg atgatcgtta atgacacagg acatgaaact gatgagaata 1441 gagcgaaggt tgagataacg cccaattcac caagagccga agccaccctg gggggttttg 1501 gaagcctagg acttgattgt gaaccgagga caggccttga cttttcagat ttgtattact 1561 tgactatgaa taacaagcac tggttggttc acaaggagtg gttccacgac attccattac 1621 cttggcacgc tggggcagac accggaactc cacactggaa caacaaagaa gcactggtag 1681 agttcaagga cgcacatgcc aaaaggcaaa ctgtcgtggt tctagggagt caagaaggag 1741 cagttcacac ggcccttgct ggagctctgg aggctgagat ggatggtgca aagggaaggc 1801 tgtcctctgg ccacttgaaa tgtcgcctga aaatggataa acttagattg aagggcgtgt 1861 catactcctt gtgtaccgca gcgttcacat tcaccaagat cccggctgaa acactgcacg 1921 ggacagtcac agtggaggta cagtacgcag ggacagatgg accttgcaag gttccagctc 1981 agatggcggt ggacatgcaa actctgaccc cagttgggag gttgataacc gccaaccccg 2041 taatcactga aagcactgag aactctaaga tgatgctgga acttgatcca ccatttgggg 2101 actcttacat tgtcatagga gtcggggaga agaagatcac ccaccactgg cacaggagtg 2161 gcagcaccat tggaaaagca tttgaagcca ctgtgagagg tgccaagaga atggcagtct 2221 tgggagacac agcctgggac tttggatcag ttggaggcgc tctcaactca ttgggcaagg 2281 gcatccatca aatttttgga gcagctttca aatcattgtt tggaggaatg tcctggttct 2341 cacaaatcct cattggaacg ttgctgatgt ggttgggtct gaacacaaag aatggatcta 2401 tttccctcat gtgcttggcc ttagggggag tgttgatctt cttatccaca gccgtctctg 2461 ctgatgtggg gtgctcggtg gacttctcaa agaaggagac gagatgcggt acaggggtgt 2521 tcgtctataa cgacgttgaa gcctggaggg acaggtacaa gtaccatcct gactcccccc 2581 gtagattggc agcagcagtc aagcaagcct gggaagatgg tatctgcggg atctcctctg 2641 tttcaagaat ggaaaacatc atgtggagat cagtagaagg ggagctcaat gcaatcctgg 2701 aagagaatgg agttcaactg acggtcgttg tgggatctgt aaaaaacccc atgtggagag 2761 gtccacagag attgcccgtg cctgtgaacg agctgcccca cggctggaag gcttggggga 2821 aatcgtactt cgttagagca gcaaagacaa ataacagctt tgtcgtggat ggtgacacac 2881 tgaaggaatg cccactcaaa catagagcat ggaacagctt tcttgtggag gatcatgggt 2941 tcggggtatt tcacactagt gtctggctca aggttagaga agattattca ttagagtgtg 3001 atccagccgt tattggaaca gctgttaagg gaaaggaggc tgtacacagt gatctaggct 3061 actggattga gagtgagaag aatgacacat ggaggctgaa gagggcccat ctgatcgaga 3121 tgaaaacatg tgaatggcca aagtcccaca cattgtggac agatggaata gaagagagtg 3181 atctgatcat acccaagtct ttagctgggc cactcagcca ccacaatacc agagagggct 3241 ataggaccca aatgaaaggg ccatggcaca gtgaagagct tgaaattcgg tttgaggaat 3301 gcccaggcac taaggtccac gtggaggaaa catgtggaac aagaggacca tctctgagat 3361 caaccactgc aagcggaagg gtgatcgagg aatggtgctg cagggagtgc acaatgcccc 3421 cactgtcgtt ccgggctaaa gatggctgtt ggtatggaat ggagataagg cccaggaaag 3481 aaccagaaag caacttagta aggtcagtgg tgactgcagg atcaactgat cacatggatc 3541 acttctccct tggagtgctt gtgattctgc tcatggtgca ggaagggctg aagaagagaa 3601 tgaccacaaa gatcatcata agcacatcaa tggcagtgct ggtagctatg atcctgggag 3661 gattttcaat gagtgacctg gctaagcttg caattttgat gggtgccacc ttcgcggaaa 3721 tgaacactgg aggagatgta gctcatctgg cgctgatagc ggcattcaaa gtcagaccag 3781 cgttgctggt atctttcatc ttcagagcta attggacacc ccgtgaaagc atgctgctgg 3841 ccttggcctc gtgtcttttg caaactgcga tctccgcctt ggaaggcgac ctgatggttc 3901 tcatcaatgg ttttgctttg gcctggttgg caatacgagc gatggttgtt ccacgcactg 3961 ataacatcac cttggcaatc ctggctgctc tgacaccact ggcccggggc acactgcttg 4021 tggcgtggag agcaggcctt gctacttgcg gggggtttat gctcctctct ctgaagggaa 4081 aaggcagtgt gaagaagaac ttaccatttg tcatggccct gggactaacc gctgtgaggc 4141 tggtcgaccc catcaacgtg gtgggactgc tgttgctcac aaggagtggg aagcggagct 4201 ggccccctag cgaagtactc acagctgttg gcctgatatg cgcattggct ggagggttcg 4261 ccaaggcaga tatagagatg gctgggccca tggccgcagt cggtctgcta attgtcagtt 4321 acgtggtctc aggaaagagt gtggacatgt acattgaaag agcaggtgac atcacatggg 4381 aaaaagatgc ggaagtcact ggaaacagtc cccggctcga tgtggcgcta gatgagagtg 4441 gtgatttctc cctggtagag gatgacggtc cccccatgag agagatcata ctcaaggtgg 4501 tcctgatgac catctgtggc atgaacccaa tagccatacc ctttgcagct ggagcgtggt 4561 acgtatacgt gaagactgga aaaaggagtg gtgctctatg ggatgtgcct gctcccaagg 4621 aagtaaaaaa gggggagacc acagatggag tgtacagagt aatgactcgt agactgctag 4681 gttcaacaca agttggagtg ggagttatgc aagagggggt ctttcacact atgtggcacg 4741 tcacaaaagg atccgcgctg agaagcggtg aagggagact tgatccatac tggggagatg 4801 tcaagcagga tctggtgtca tactgtggtc catggaagct agatgccgcc tgggacgggc 4861 acagcgaggt gcagctcttg gccgtgcccc ccggagagag agcgaggaac atccagactc 4921 tgcccggaat atttaagaca aaggatgggg acattggagc ggttgcgctg gattacccag 4981 caggaacttc aggatctcca atcctagaca agtgtgggag agtgatagga ctttatggca 5041 atggggtcgt gatcaaaaat gggagttatg ttagtgccat cacccaaggg aggagggagg 5101 aagagactcc tgttgagtgc ttcgagcctt cgatgctgaa gaagaagcag ctaactgtct 5161 tagacttgca tcctggagct gggaaaacca ggagagttct tcctgaaata gtccgtgaag 5221 ctataaaaac aagactccgt actgtgatct tagctccaac cagggttgtc gctgctgaaa 5281 tggaggaagc ccttagaggg cttccagtgc gttatatgac aacagcagtc aatgtcaccc 5341 attctggaac agaaatcgtc gacttaatgt gccatgccac cttcacttca cgtctactac 5401 agccaatcag agtccccaac tataatctgt atattatgga tgaggcccac ttcacagatc 5461 cctcaagtat agcagcaaga ggatacattt caacaagggt tgagatgggc gaggcggctg 5521 ccatcttcat gaccgccacg ccaccaggaa cccgtgacgc atttccggac tccaactcac 5581 caattatgga caccgaagtg gaagtcccag agagagcctg gagctcaggc tttgattggg 5641 tgacggatca ctctggaaaa acagtttggt ttgttccaag cgtgaggaac ggcaatgaga 5701 tcgcagcttg tctgacaaag gctggaaaac gggtcataca gctcagcaga aagacttttg 5761 agacagagtt ccagaaaaca aaacatcaag agtgggactt tgtcgtgaca accgacattt 5821 cagagatggg cgccaacttt aaagctgacc gtgtcataga ttccaggaga tgcctaaagc 5881 cggtcatact tgatggcgag agagtcattc tggctggacc catgcctgtc acacatgcca 5941 gcgctgccca gaggaggggg cgcataggca ggaatcccaa caaacctgga gatgagtatc 6001 tgtatggagg tgggtgcgca gagactgacg aagaccatgc acactggctt gaagcaagaa 6061 tgctccttga caatatttac ctccaagatg gcctcatagc ctcgctctat cgacctgagg 6121 ccgacaaagt agcagccatt gagggagagt tcaagcttag gacggagcaa aggaagacct 6181 ttgtggaact catgaaaaga ggagatcttc ctgtttggct ggcctatcag gttgcatctg 6241 ccggaataac ttacacagat agaagatggt gctttgatgg cacgaccaac aacaccataa 6301 tggaagacag tgtgccggca gaggtgtgga ccagacacgg agagaaaaga gtgctcaaac 6361 cgaggtggat ggacgccaga gtttgttcag atcatgcggc cctgaagtca ttcaaggagt 6421 ttgccgctgg gaaaagagga gcggcttttg gagtgatgga agccctggga acactgccag 6481 gacacatgac agagagattc caggaagcca ttgacaacct cgctgtgctc atgcgggcag 6541 agactggaag caggccttac aaagccgcgg cggcccaatt gccggagacc ctagagacca 6601 ttatgctttt ggggttgctg ggaacagtct cgctgggaat ctttttcgtc ttgatgagga 6661 acaagggcat agggaagatg ggctttggaa tggtgactct tggggccagc gcatggctca 6721 tgtggctctc ggaaattgag ccagccagaa ttgcatgtgt cctcattgtt gtgttcctac 6781 tgctggtggt gctcatacct gagccagaaa agcaaagatc tccccaggac aaccaaatgg 6841 caatcatcat catggtagca gtaggtcttc tgggcttgat caccgccaat gaactcggat 6901 ggttggagag aacaaagagt gacctaagcc atctaatggg aaggagagag gagggagcaa 6961 ccataggatt ctcaatggac attgacctgc ggccagcctc agcttgggcc atctatgctg 7021 ccttgacaac tttcatcacc ccagccgtcc aacatgcagt gaccacttca tacaacaact 7081 actccttaat ggcgatggcc acgcaagctg gagtgttgtt tggtatgggc aaagggatgc 7141 cattctacgc atgggacttt ggagtcccgc tgctaatgat aggttgctac tcacaattaa 7201 cacccctgac cctaatagtg gccatcattt tgctcgtggc gcactacatg tacttgatcc 7261 cagggctgca ggcagcagct gcgcgtgctg cccagaagag aacggcagct ggcatcatga 7321 agaaccctgt tgtggatgga atagtggtga ctgacattga cacaatgaca attgaccccc 7381 aagtggagaa aaagatggga caggtgctac tcatagcagt agccgtctcc agcgccatac 7441 tgtcgcggac cgcctggggg tggggggagg ctggggccct gatcacagcc gcaacttcca 7501 ctttgtggga aggctctccg aacaagtact ggaactcctc tacagccact tcactgtgta 7561 acatttttag gggaagttac ttggctggag cttctctaat ctacacagta acaagaaacg 7621 ctggcttggt caagagacgt gggggtggaa caggagagac cctgggagag aaatggaagg 7681 cccgcttgaa ccagatgtcg gccctggagt tctactccta caaaaagtca ggcatcaccg 7741 aggtgtgcag agaagaggcc cgccgcgccc tcaaggacgg tgtggcaacg ggaggccatg 7801 ctgtgtcccg aggaagtgca aagctgagat ggttggtgga gcggggatac ctgcagccct 7861 atggaaaggt cattgatctt ggatgtggca gagggggctg gagttactac gccgccacca 7921 tccgcaaagt tcaagaagtg aaaggataca caaaaggagg ccctggtcat gaagaacccg 7981 tgttggtgca aagctatggg tggaacatag tccgtctcaa gagtggggtg gacgtctttc 8041 atatggcggc tgagccgtgt gacacgttgc tgtgtgacat aggcgagtca tcatctagtc 8101 ctgaagtcga agaagcacgg acgctcagag tcctctccat ggtgggggat tggcttgaaa 8161 aaagaccagg agccttttgt ataaaagtgt tgtgcccata caccagcact atgatggaaa 8221 ccctggagcg actgcagcgt aggtatgggg gaggactggt cagagtgcca ctctcccgca 8281 actctacaca tgagatgtac tgggtttctg gagcgaaaag caacaccata aaaagtgtgt 8341 ccaccacgag ccagctcctc ttggggcgca tggacgggcc taggaggcca gtgaaatatg 8401 aggaggatgt gaatctcggc tctggcacgc gggctgtggt aagctgcgct gaagctccca 8461 acatgaagat cattggtaac cgcattgaaa ggatccgcag tgagcacgcg gaaacgtggt 8521 tctttgacga gaaccaccca tataggacat gggcttacca tggaagctat gaggccccca 8581 cacaagggtc agcatcctct ctagtaaacg gggttgtcag gctcctgtca aaaccctggg 8641 atgtggtgac tggagtcaca ggaatagcca tgaccgacac cacaccgtat ggtcagcaaa 8701 gagttttcaa ggaaaaagtg gacactaggg tgccagaccc ccaagaaggc actcgtcagg 8761 ttatgagcat ggtctcttcc tggttgtgga aagagctagg caaacacaaa cggccacgag 8821 tctgtaccaa agaagagttc atcaacaagg ttcgtagcaa tgcagcatta ggggcaatat 8881 ttgaagagga aaaagagtgg aagactgcag tggaagctgt gaacgatcca aggttctggg 8941 ctctagtgga caaggaaaga gagcaccacc tgagaggaga gtgccagagt tgtgtgtaca 9001 acatgatggg aaaaagagaa aagaaacaag gggaatttgg aaaggccaag ggcagccgcg 9061 ccatctggta tatgtggcta ggggctagat ttctagagtt cgaagccctt ggattcttga 9121 acgaggatca ctggatgggg agagagaact caggaggtgg tgttgaaggg ctgggattac 9181 aaagactcgg atatgtccta gaagagatga gtcgcatacc aggaggaagg atgtatgcag 9241 atgacactgc tggctgggat acccgcatca gcaggtttga tctagagaat gaagctctaa 9301 tcaccaacca aatggagaaa gggcacaggg ccttggcatt ggccataatc aagtacacat 9361 accaaaacaa agtggtaaag gtccttagac cagctgaaaa agggaaaaca gttatggaca 9421 ttatttcgag acaagaccaa agggggagcg gacaagtcgt cacttacgct cttaacacat 9481 ttaccaacct agtggtgcaa ctcattcgga atatggaggc tgaggaagtt ctagagatgc 9541 aagacttgtg gctgctgcgg aggtcagaga aagtgaccaa ctggttgcag agcaacggat 9601 gggataggct caaacgaatg gcagtcagtg gagatgattg cgttgtgaag ccaattgatg 9661 ataggtttgc acatgccctc aggttcttga atgatatggg aaaagttagg aaggacacac 9721 aagagtggaa accctcaact ggatgggaca actgggaaga agttccgttt tgctcccacc 9781 acttcaacaa gctccatctc aaggacggga ggtccattgt ggttccctgc cgccaccaag 9841 atgaactgat tggccgggcc cgcgtctctc caggggcggg atggagcatc cgggagactg 9901 cttgcctagc aaaatcatat gcgcaaatgt ggcagctcct ttatttccac agaagggacc 9961 tccgactgat ggccaatgcc atttgttcat ctgtgccagt tgactgggtt ccaactggga 10021 gaactacctg gtcaatccat ggaaagggag aatggatgac cactgaagac atgcttgtgg 10081 tgtggaacag agtgtggatt gaggagaacg accacatgga agacaagacc ccagttacga 10141 aatggacaga cattccctat ttgggaaaaa gggaagactt gtggtgtgga tctctcatag 10201 ggcacagacc gcgcaccacc tgggctgaga acattaaaaa cacagtcaac atggtgcgca 10261 ggatcatagg tgaggaagaa aagtacatgg actacctatc cacccaagtt cgctacttgg 10321 gtgaagaagg gtctacacct ggagtgctgt aagcaccaat cttaatgttg tcaggcctgc 10381 tagtcagcca cagcttgggg aaagctgtgc agcctgtgac ccccccagga gaagctggga 10441 aaccaagcct atagtcaggc cgagaacgcc atggcacgga agaagccatg ctgcctgtga 10501 gcccctcaga ggacactgag tcaaaaaacc ccacgcgctt ggaggcgcag gatgggaaaa 10561 gaaggtggcg accttcccca cccttcaatc tggggcctga actggagat

Sequences producing significant alignments: Select:AllNone Selected:0 AlignmentsDownloadGenBankGraphicsDistance tree of resultsShow/hide columns of the table presenting sequences producing significant alignments Sequences producing significant alignments: Select for downloading or viewing reports Description Max score Total score Query cover E value Ident Accession Select seq gb|KX842449.1| Zika virus isolate ZIKV/Human/USA/2016/ZF10.UR-010 polyprotein gene, complete cds 18503 18503 100% 0.0 99% KX842449.1 Select seq gb|KX832731.1| Zika virus isolate ZIKV/Human/USA/2016/ZL2.SA-Hu0015 polyprotein gene, complete cds 18494 18494 100% 0.0 99% KX832731.1 Select seq gb|KX838905.1| Zika virus isolate ZIKV/Aedes_aegypti/USA/2016/ZM2-7719 polyprotein gene, complete cds 18491 18491 100% 0.0 99% KX838905.1 Select seq gb|KX838904.1| Zika virus isolate ZIKV/Aedes_aegypti/USA/2016/ZM1-7501 polyprotein gene, complete cds 18485 18485 100% 0.0 99% KX838904.1 Select seq gb|KU853013.1| Zika virus isolate Dominican Republic/2016/PD2, complete genome 18440 18440 100% 0.0 99% KU853013.1 Select seq gb|KU853012.1| Zika virus isolate Dominican Republic/2016/PD1, complete genome 18440 18440 100% 0.0 99% KU853012.1 Select seq gb|KX673530.1| Zika virus isolate PHE_semen_Guadeloupe, complete genome 18419 18419 100% 0.0 99% KX673530.1 Select seq gb|KX838906.1| Zika virus isolate ZIKV/Aedes_aegypti/USA/2016/ZM3-7729 polyprotein gene, complete cds 18410 18410 100% 0.0 99% KX838906.1 Select seq gb|KX447510.1| Zika virus isolate 1_0049_PF polyprotein gene, complete cds 18350 18350 100% 0.0 99% KX447510.1 Select seq gb|KX280026.1| Zika virus isolate Paraiba_01, complete genome 18346 18346 100% 0.0 99% KX280026.1 Select seq gb|KX447512.1| Zika virus isolate 1_0181_PF polyprotein gene, complete cds 18341 18341 100% 0.0 99% KX447512.1 Select seq gb|KX369547.1| Zika virus strain PF13/251013-18, complete genome 18341 18341 100% 0.0 99% KX369547.1 Select seq gb|KU509998.3| Zika virus strain Haiti/1225/2014, complete genome 18341 18341 100% 0.0 99% KU509998.3 Select seq gb|KJ776791.2| Zika virus strain H/PF/2013, complete genome 18337 18337 100% 0.0 99% KJ776791.2 Select seq gb|KX447509.1| Zika virus isolate 1_0087_PF polyprotein gene, complete cds 18337 18337 100% 0.0 99% KX447509.1 Select seq gb|KU991811.1| Zika virus isolate Brazil/2016/INMI1 polyprotein gene, complete cds 18337 18337 100% 0.0 99% KU991811.1 Select seq gb|KU729217.2| Zika virus isolate BeH823339 polyprotein gene, complete cds 18337 18337 100% 0.0 99% KU729217.2 Select seq gb|KX447513.1| Zika virus isolate 1_0134_PF polyprotein gene, complete cds 18332 18332 100% 0.0 99% KX447513.1 Select seq gb|KX811222.1| Zika virus isolate Brazil_2015_MG, complete genome 18328 18328 100% 0.0 99% KX811222.1 Select seq gb|KX197205.1| Zika virus isolate 9, complete genome 18328 18328 100% 0.0 99% KX197205.1 Select seq gb|KX447515.1| Zika virus isolate 1_0030_PF polyprotein gene, complete cds 18328 18328 100% 0.0 99% KX447515.1 Select seq gb|KX447511.1| Zika virus isolate 1_0015_PF polyprotein gene, complete cds 18328 18328 100% 0.0 99% KX447511.1 Select seq gb|KU321639.1| Zika virus strain ZikaSPH2015, complete genome 18328 18328 100% 0.0 99% KU321639.1 Select seq gb|KX879604.1| Zika virus isolate SN089, complete genome 18323 18323 100% 0.0 99% KX879604.1 Select seq gb|KX447514.1| Zika virus isolate 1_0035_PF polyprotein gene, complete cds 18323 18323 100% 0.0 99% KX447514.1 Select seq gb|KX051563.1| Zika virus isolate Haiti/1/2016, complete genome 18323 18323 100% 0.0 99% KX051563.1 Select seq gb|KX447516.1| Zika virus isolate 1_0111_PF polyprotein gene, complete cds 18319 18319 100% 0.0 99% KX447516.1 Select seq gb|KU729218.1| Zika virus isolate BeH828305 polyprotein gene, complete cds 18319 18319 100% 0.0 99% KU729218.1 Select seq gb|KU707826.1| Zika virus isolate SSABR1, complete genome 18319 18319 100% 0.0 99% KU707826.1 Select seq gb|KU527068.1| Zika virus strain Natal RGN, complete genome 18319 18319 100% 0.0 99% KU527068.1 Select seq gb|KU365779.1| Zika virus strain BeH819966 polyprotein gene, complete cds 18319 18319 100% 0.0 99% KU365779.1 Select seq gb|KX879603.1| Zika virus isolate SN062, complete genome 18314 18314 100% 0.0 99% KX879603.1 Select seq gb|KX262887.1| Zika virus isolate 103451, complete genome 18314 18314 100% 0.0 99% KX262887.1 Select seq gb|KX197192.1| Zika virus isolate ZIKV/H.sapiens/Brazil/PE243/2015, complete genome 18314 18314 100% 0.0 99% KX197192.1 Select seq gb|KU926310.1| Zika virus isolate Rio-S1, complete genome 18314 18314 100% 0.0 99% KU926310.1 Select seq gb|KU926309.1| Zika virus isolate Rio-U1, complete genome 18314 18314 100% 0.0 99% KU926309.1 Select seq gb|KU940228.1| Zika virus isolate Bahia07, partial genome 18310 18310 100% 0.0 99% KU940228.1 Select seq gb|KX694534.1| Zika virus strain ZIKV/Homo sapiens/HND/R103451/2015, complete genome 18305 18305 100% 0.0 99% KX694534.1 Select seq gb|KX198135.1| Zika virus strain ZIKV/Homo sapiens/PAN/BEI-259634_V4/2016, complete genome 18305 18305 100% 0.0 99% KX198135.1 Select seq gb|KU647676.1| Zika virus strain MRS_OPY_Martinique_PaRi_2015 polyprotein gene, complete cds 18305 18305 100% 0.0 99% KU647676.1 Select seq gb|KU501217.1| Zika virus strain 8375 polyprotein gene, complete cds 18305 18305 100% 0.0 99% KU501217.1 Select seq gb|KU365780.1| Zika virus strain BeH815744 polyprotein gene, complete cds 18305 18305 100% 0.0 99% KU365780.1 Select seq gb|KU501216.1| Zika virus strain 103344 polyprotein gene, complete cds 18301 18301 100% 0.0 99% KU501216.1 Select seq gb|KU365777.1| Zika virus strain BeH818995 polyprotein gene, complete cds 18301 18301 100% 0.0 99% KU365777.1 Select seq gb|KX447517.1| Zika virus isolate 1_0038_PF polyprotein gene, complete cds 18296 18296 100% 0.0 99% KX447517.1 Select seq gb|KU758877.1| Zika virus isolate 17271 polyprotein gene, complete cds 18296 18296 100% 0.0 99% KU758877.1 Select seq gb|KX247646.1| Zika virus isolate Zika virus/Homo sapiens/COL/UF-1/2016, complete genome 18296 18296 100% 0.0 99% KX247646.1 Select seq gb|KX156776.1| Zika virus strain ZIKV/Homo sapiens/PAN/CDC-259364_V1-V2/2015, complete genome 18296 18296 100% 0.0 99% KX156776.1 Select seq gb|KX520666.1| Zika virus isolate HS-2015-BA-01 polyprotein gene, complete cds 18292 18292 100% 0.0 99% KX520666.1 Select seq gb|KX156774.1| Zika virus strain ZIKV/Homo sapiens/PAN/CDC-259359_V1-V3/2015, complete genome 18292 18292 100% 0.0 99% KX156774.1 Select seq gb|KU497555.1| Zika virus isolate Brazil-ZKV2015, complete genome 18292 18292 99% 0.0 99% KU497555.1 Select seq gb|KU820897.5| Zika virus isolate FLR polyprotein gene, complete cds 18287 18287 100% 0.0 99% KU820897.5 Select seq gb|KX247632.1| Zika virus isolate MEX_I_7 polyprotein gene, complete cds 18287 18287 100% 0.0 99% KX247632.1 Select seq gb|KX156775.1| Zika virus strain ZIKV/Homo sapiens/PAN/CDC-259249_V1-V3/2015, complete genome 18287 18287 100% 0.0 99% KX156775.1 Select seq gb|KX087102.1| Zika virus strain ZIKV/Homo sapiens/COL/FLR/2015, complete genome 18287 18287 100% 0.0 99% KX087102.1 Select seq gb|KU922960.1| Zika virus isolate MEX/InDRE/Sm/2016, complete genome 18287 18287 100% 0.0 99% KU922960.1 Select seq gb|KU365778.1| Zika virus strain BeH819015 polyprotein gene, complete cds 18287 18287 100% 0.0 99% KU365778.1 Select seq gb|KU312312.1| Zika virus isolate Z1106033 polyprotein gene, complete cds 18287 18287 100% 0.0 99% KU312312.1 Select seq gb|KU922923.1| Zika virus isolate MEX/InDRE/Lm/2016, complete genome 18283 18283 100% 0.0 99% KU922923.1 Select seq gb|KX856011.1| Zika virus strain ZIKV/Aedes sp./MEX_I-44/2016, complete genome 18278 18278 100% 0.0 99% KX856011.1 Select seq gb|KX806557.1| Zika virus isolate TS17-2016, complete genome 18278 18278 100% 0.0 99% KX806557.1 Select seq gb|KX548902.1| Zika virus isolate ZIKV/COL/FCC00093/2015 polyprotein gene, complete cds 18278 18278 100% 0.0 99% KX548902.1 Select seq gb|KX446951.1| Zika virus strain ZIKV/Aedes.sp/MEX/MEX_I-7/2016, complete genome 18278 18278 100% 0.0 99% KX446951.1 Select seq gb|KU937936.1| Zika virus isolate ZIKVNL00013 polyprotein gene, complete cds 18278 18278 100% 0.0 99% KU937936.1 Select seq gb|KU501215.1| Zika virus strain PRVABC59, complete genome 18278 18278 100% 0.0 99% KU501215.1 Select seq gb|KX601168.1| Zika virus strain ZIKV/Homo Sapiens/PRI/PRVABC59/2015, complete genome 18274 18274 100% 0.0 99% KX601168.1 Select seq gb|KX446950.1| Zika virus strain ZIKV/Aedes.sp/MEX/MEX_2-81/2016, complete genome 18274 18274 100% 0.0 99% KX446950.1 Select seq gb|KX087101.2| Zika virus strain ZIKV/Homo sapiens/PRI/PRVABC59/2015, complete genome 18274 18274 100% 0.0 99% KX087101.2 Select seq gb|KU870645.1| Zika virus isolate FB-GWUH-2016, complete genome 18274 18274 100% 0.0 99% KU870645.1 Select seq gb|KX702400.1| Zika virus strain Zika virus/Homo sapiens/VEN/UF-1/2016, complete genome 18269 18269 100% 0.0 99% KX702400.1 Select seq gb|KX377337.1| Zika virus strain PRVABC-59, complete genome 18269 18269 100% 0.0 99% KX377337.1 Select seq gb|KX766029.1| Zika virus isolate R116265, complete genome 18260 18260 100% 0.0 99% KX766029.1 Select seq gb|KU820898.1| Zika virus isolate GZ01 polyprotein gene, complete cds 18260 18260 100% 0.0 99% KU820898.1 Select seq gb|KX056898.1| Zika virus isolate Zika virus/GZ02/2016 polyprotein gene, complete cds 18256 18256 100% 0.0 99% KX056898.1 Select seq gb|KU955590.1| Zika virus isolate Z16019 polyprotein gene, complete cds 18256 18256 100% 0.0 99% KU955590.1 Select seq gb|KX766028.1| Zika virus isolate R114916, complete genome 18253 18253 100% 0.0 99% KX766028.1 Select seq gb|KU740184.2| Zika virus isolate GD01 polyprotein gene, complete cds 18251 18251 100% 0.0 99% KU740184.2 Select seq gb|KU761564.1| Zika virus isolate GDZ16001 polyprotein gene, complete cds 18251 18251 100% 0.0 99% KU761564.1 Select seq gb|KX117076.1| Zika virus isolate Zhejiang04, complete genome 18247 18247 100% 0.0 99% KX117076.1 Select seq gb|KX185891.1| Zika virus isolate Zika virus/CN/SZ02/2016 polyprotein gene, complete cds 18238 18238 100% 0.0 99% KX185891.1 Select seq gb|KU963796.1| Zika virus isolate SZ-WIV01 polyprotein gene, complete cds 18238 18238 100% 0.0 99% KU963796.1 Select seq gb|KX253996.1| Zika virus isolate ZKC2/2016, complete genome 18233 18233 100% 0.0 99% KX253996.1 Select seq gb|KU955589.1| Zika virus isolate Z16006 polyprotein gene, complete cds 18233 18233 100% 0.0 99% KU955589.1 Select seq gb|KU820899.2| Zika virus isolate ZJ03, complete genome 18233 18233 100% 0.0 99% KU820899.2 Select seq gb|KX266255.1| Zika virus isolate ZIKV_SMGC-1, complete genome 18229 18229 100% 0.0 99% KX266255.1 Select seq gb|KU866423.2| Zika virus isolate Zika virus/SZ01/2016/China polyprotein gene, complete cds 18229 18229 100% 0.0 99% KU866423.2 Select seq gb|KU940224.1| Zika virus isolate Bahia09, partial genome 18215 18215 99% 0.0 99% KU940224.1 Select seq gb|KU744693.1| Zika virus isolate VE_Ganxian, complete genome 18094 18094 100% 0.0 99% KU744693.1 Select seq gb|KX827309.1| Zika virus isolate ZKA-16-291 polyprotein gene, complete cds 18071 18071 100% 0.0 99% KX827309.1 Select seq gb|KX813683.1| Zika virus isolate ZKA-16-097 polyprotein gene, complete cds 18058 18058 100% 0.0 99% KX813683.1 Select seq gb|KU681081.3| Zika virus isolate Zika virus/H.sapiens-tc/THA/2014/SV0127- 14, complete genome 18004 18004 100% 0.0 99% KU681081.3 Select seq gb|KX694532.1| Zika virus strain ZIKV/Homo sapiens/THA/PLCal_ZV/2013, complete genome 17881 17881 100% 0.0 99% KX694532.1 Select seq gb|KU955593.1| Zika virus isolate Zika virus/H.sapiens-tc/KHM/2010/FSS13025, complete genome 17697 17697 100% 0.0 98% KU955593.1 Select seq gb|JN860885.1| Zika virus isolate FSS13025 polyprotein gene, partial cds 17695 17695 99% 0.0 98% JN860885.1 Select seq gb|KF993678.1| Zika virus strain PLCal_ZV from Canada polyprotein gene, partial cds 17650 17650 98% 0.0 99% KF993678.1 Select seq gb|EU545988.1| Zika virus polyprotein gene, complete cds 17542 17542 100% 0.0 98% EU545988.1 Select seq gb|KU681082.3| Zika virus isolate Zika virus/H.sapiens-tc/PHL/2012/CPC-0740, complete genome 17394 17394 100% 0.0 98% KU681082.3 Select seq gb|KX601167.1| Zika virus strain ZIKV/Aedes sp./MYS/P6-740/1966, complete genome 16372 16372 100% 0.0 95% KX601167.1 Select seq gb|KX694533.1| Zika virus strain ZIKV/Aedes aegypti/MYS/P6-740/1966, complete genome 16363 16363 100% 0.0 95% KX694533.1 Select seq gb|HQ234499.1| Zika virus isolate P6-740 polyprotein gene, partial cds 16363 16363 99% 0.0 95% HQ234499.1

LOCUS KX922706 10610 bp RNA linear VRL 05-OCT-2016 DEFINITION Zika virus isolate ZIKV/Homo_sapiens/USA/2016/FL038U polyprotein gene, complete cds. ACCESSION KX922706 VERSION KX922706.1 GI:1071930516 DBLINK BioProject: PRJNA342539 BioSample: SAMN05853065 KEYWORDS . SOURCE Zika virus ORGANISM Zika virus Viruses; ssRNA viruses; ssRNA positive-strand viruses, no DNA stage; Flaviviridae; Flavivirus. REFERENCE 1 (bases 1 to 10610) AUTHORS Grubaugh,N., Tan,A., Gangavarupu,K., Oliveira,G., Robles-Sikisaka,R., Cone,M., Kopp,E., Hogan,K., Cannons,A., Michael,S., Isern,S. and Andersen,K. TITLE Zika virus sequences from Florida, USA, 2016 JOURNAL Unpublished REFERENCE 2 (bases 1 to 10610) AUTHORS Grubaugh,N., Tan,A., Gangavarupu,K., Oliveira,G., Robles-Sikisaka,R., Cone,M., Kopp,E., Hogan,K., Cannons,A., Michael,S., Isern,S. and Andersen,K. TITLE Direct Submission JOURNAL Submitted (29-SEP-2016) Department of Immunology and Microbial Science, The Scripps Research Institute, 10550 North Torrey Pines Road, IMM-210, La Jolla, CA 92037, USA COMMENT ##Assembly-Data-START## Assembly Method :: NovoAlign v. V3.04 Sequencing Technology :: Illumina ##Assembly-Data-END## FEATURES Location/Qualifiers source 1..10610 /organism="Zika virus" /mol_type="genomic RNA" /isolate="ZIKV/Homo_sapiens/USA/2016/FL038U" /isolation_source="urine" /host="Homo sapiens" /db_xref="taxon:64320" /country="USA: Miami, Florida" /collection_date="04-Aug-2016" CDS 82..10353 /codon_start=1 /product="polyprotein" /protein_id="AOS90223.1" /db_xref="GI:1071930517" /translation="MKNPKKKSGGFRIVNMLKRGVARVSPFGGLKRLPAGLLLGHGPI RMVLAILAFLRFTAIKPSLGLINRWGSVGKKEAMEIIKKFKKDLAAMLRIINARKEKK RRGADTSVGIVGLLLTTAMAAEVTRRGSAYYMYLDRNDAGEAISFPTTLGMNKCYIQI MDLGHMCDATMSYECPMLDEGVEPDDVDCWCNTTSTWVVYGTCHHKKGEARRSRRAVT LPSHSTRKLQTRSQTWLESREYTKHLIRVENWIFRNPGFALAAAAIAWLLGSSTSQKV IYLVMILLIAPAYSIRCIGVSNRDFVEGMSGGTWVDVVLEHGGCVTVMAQDKPTVDIE LVTTTVSNMAEVRSYCYEASISDMASDSRCPTQGEAYLDKQSDTQYVCKRTLVDRGWG NGCGLFGKGSLVTCAKFACSKKMTGKSIQPENLEYRIMLSVHGSQHSGMIVNDTGHET DENRAKVEITPNSPRAEATLGGFGSLGLDCEPRTGLDFSDLYYLTMNNKHWLVHKEWF HDIPLPWHAGADTGTPHWNNKEALVEFKDAHAKRQTVVVLGSQEGAVHTALAGALEAE MDGAKGRLSSGHLKCRLKMDKLRLKGVSYSLCTAAFTFTKIPAETLHGTVTVEVQYAG TDGPCKVPAQMAVDMQTLTPVGRLITANPVITESTENSKMMLELDPPFGDSYIVIGVG EKKITHHWHRSGSTIGKAFEATVRGAKRMAVLGDTAWDFGSVGGALNSLGKGIHQIFG AAFKSLFGGMSWFSQILIGTLLMWLGLNTKNGSISLMCLALGGVLIFLSTAVSADVGC SVDFSKKETRCGTGVFVYNDVEAWRDRYKYHPDSPRRLAAAVKQAWEDGICGISSVSR MENIMWRSVEGELNAILEENGVQLTVVVGSVKNPMWRGPQRLPVPVNELPHGWKAWGK SYFVRAAKTNNSFVVDGDTLKECPLKHRAWNSFLVEDHGFGVFHTSVWLKVREDYSLE CDPAVIGTAVKGKEAVHSDLGYWIESEKNDTWRLKRAHLIEMKTCEWPKSHTLWTDGI EESDLIIPKSLAGPLSHHNTREGYRTQMKGPWHSEELEIRFEECPGTKVHVEETCGTR GPSLRSTTASGRVIEEWCCRECTMPPLSFRAKDGCWYGMEIRPRKEPESNLVRSVVTA GSTDHMDHFSLGVLVILLMVQEGLKKRMTTKIIISTSMAVLVAMILGGFSMSDLAKLA ILMGATFAEMNTGGDVAHLALIAAFKVRPALLVSFIFRANWTPRESMLLALASCLLQT AISALEGDLMVLINGFALAWLAIRAMVVPRTDNITLAILAALTPLARGTLLVAWRAGL ATCGGFMLLSLKGKGSVKKNLPFVMALGLTAVRLVDPINVVGLLLLTRSGKRSWPPSE VLTAVGLICALAGGFAKADIEMAGPMAAVGLLIVSYVVSGKSVDMYIERAGDITWEKD AEVTGNSPRLDVALDESGDFSLVEDDGPPMREIILKVVLMTICGMNPIAIPFAAGAWY VYVKTGKRSGALWDVPAPKEVKKGETTDGVYRVMTRRLLGSTQVGVGVMQEGVFHTMW HVTKGSALRSGEGRLDPYWGDVKQDLVSYCGPWKLDAAWDGHSEVQLLAVPPGERARN IQTLPGIFKTKDGDIGAVALDYPAGTSGSPILDKCGRVIGLYGNGVVIKNGSYVSAIT QGRREEETPVECFEPSMLKKKQLTVLDLHPGAGKTRRVLPEIVREAIKTRLRTVILAP TRVVAAEMEEALRGLPVRYMTTAVNVTHSGTEIVDLMCHATFTSRLLQPIRVPNYNLY IMDEAHFTDPSSIAARGYISTRVEMGEAAAIFMTATPPGTRDAFPDSNSPIMDTEVEV PERAWSSGFDWVTDHSGKTVWFVPSVRNGNEIAACLTKAGKRVIQLSRKTFETEFQKT KHQEWDFVVTTDISEMGANFKADRVIDSRRCLKPVILDGERVILAGPMPVTHASAAQR RGRIGRNPNKPGDEYLYGGGCAETDEDHAHWLEARMLLDNIYLQDGLIASLYRPEADK VAAIEGEFKLRTEQRKTFVELMKRGDLPVWLAYQVASAGIAYTDRRWCFDGTTNNTIM EDSVPAEVWTRHGEKRVLKPRWMDARVCSDHAALKSFKEFAAGKRGAAFGVMEALGTL PGHMTERFQEAIDNLAVLMRAETGSRPYKAAAAQLPETLETIMLLGLLGTVSLGIFFV LMRNKGIGKMGFGMVTLGASAWLMWLSEIEPARIACVLIVVFLLLVVLIPEPEKQRSP QDNQMAIIIMVAVGLLGLITANELGWLERTKSDLSHLMGRREEGATIGFSMDIDLRPA SAWAIYAALTTFITPAVQHAVTTSYNNYSLMAMATQAGVLFGMGKGMPFYAWDFGVPL LMIGCYSQLTPLTLIVAIILLVAHYMYLIPGLQAAAARAAQKRTAAGIMKNPVVDGIV VTDIDTMTIDPQVEKKMGQVLLIAVAVSSAILSRTAWGWGEAGALITAATSTLWEGSP NNYWNSSTATSLCNIFRGSYLAGASLIYTVTRNAGLVKRRGGGTGETLGEKWKARLNQ MSALEFYSYKKSGITEVCREEARRALKDGVATGGHAVSRGSAKLRWLVERGYLQPYGK VIDLGCGRGGWSYYAATIRKVQEVKGYTKGGPGHEEPVLVQSYGWNIVRLKSGVDVFH MAAEPCDTLLCDIGESSSSPEVEEARTLRVLSMVGDWLEKRPGAFCIKVLCPYTSTMM ETLERLQRRYGGGLVRVPLSRNSTHEMYWVSGAKSNTIKSVSTTSQLLLGRMDGPRRP VKYEEDVNLGSGTRAVVSCAEAPNMKIIGNRIERIRSEHAETWFFDENHPYRTWAYHG SYEAPTQGSASSLVNGVVRLLSKPWDVVTGVTGIAMTDTTPYGQQRVFKEKVDTRVPD PQEGTRQVMSMVSSWLWKELGKHKRPRVCTKEEFINKVRSNAALGAIFEEEKEWKTAV EAVNDPRFWALVDKEREHHLRGECQSCVYNMMGKREKKQGEFGKAKGSRAIWYMWLGA RFLEFEALGFLNEDHWMGRENSGGGVEGLGLQRLGYVLEEMSRIPGGRMYADDTAGWD TRISRFDLENEALITNQMEKGHRALALAIIKYTYQNKVVKVLRPAEKGKTVMDIISRQ DQRGSGQVVTYALNTFTNLVVQLIRNMEAEEVLEMQDLWLLRRSEKVTNWLQSNGWDR LKRMAVSGDDCVVKPIDDRFAHALRFLNDMGKVRKDTQEWKPSTGWDNWEEVPFCSHH FNKLHLKDGRSIVVPCRHQDELIGRARVSPGAGWSIRETACLAKSYAQMWQLLYFHRR DLRLMANAICSSVPVDWVPTGRTTWSIHGKGEWMTIEDMLVVWNRVWIEENDHMEDKT PVTKWTDIPYLGKREDLWCGSLIGHRPRTTWAENIKNTVNMVRRIIGEEEKYMDYLST QVRYLGEEGSTPGVL" ORIGIN 1 gcgacagttc gagtttgaag cgaaagctag caacagtatc aacaggtttt attttggatt 61 tggaaacgag agtttctggt catgaaaaac ccaaaaaaga aatccggagg attccggatt 121 gtcaatatgc taaaacgcgg agtagcccgt gtgagcccct ttgggggctt gaagaggctg 181 ccagccggac ttctgctggg tcatgggccc atcaggatgg tcttggcgat tctagccttt 241 ttgagattca cggcaatcaa gccatcactg ggtctcatca atagatgggg ttcagtgggg 301 aaaaaagagg ctatggaaat aataaagaag ttcaagaaag atctggctgc catgctgaga 361 ataatcaatg ctaggaagga gaagaagaga cgaggcgcag atactagtgt cggaattgtt 421 ggcctcctgc tgaccacagc tatggcagcg gaggtcacta gacgtgggag tgcatactac 481 atgtacttgg acagaaacga tgctggggag gccatatctt tcccaaccac attggggatg 541 aataagtgtt atatacagat catggatctt ggacacatgt gtgatgccac catgagctat 601 gaatgcccta tgctggatga gggggtggaa ccagatgacg tcgattgttg gtgcaacacg 661 acgtcaactt gggttgtgta cggaacctgc catcacaaaa aaggtgaagc acggagatct 721 agaagagctg tgacgctccc ctcccattcc actaggaagc tgcaaacgcg gtcgcaaacc 781 tggttggaat caagagaata cacaaagcac ttgattagag tcgaaaattg gatattcagg 841 aaccctggct tcgcgttagc agcagctgcc atcgcttggc ttttgggaag ctcaacgagc 901 caaaaagtta tatacttggt catgatactg ctgattgccc cggcatacag catcaggtgc 961 ataggagtca gcaataggga ctttgtggaa ggtatgtcag gtgggacttg ggttgatgtt 1021 gtcttggaac atggaggctg tgtcaccgta atggcacagg acaaaccgac tgtcgacata 1081 gagctggtta caacaacagt cagcaacatg gcggaggtaa gatcctactg ctatgaggca 1141 tcaatatcag acatggcttc ggacagccgc tgcccaacac aaggtgaagc ctaccttgac 1201 aagcaatcag acactcaata tgtctgcaaa agaacgttag tggacagagg ctggggaaat 1261 ggatgtggac tttttggcaa agggagcctg gtgacatgcg ctaagtttgc atgctccaag 1321 aaaatgaccg ggaagagcat ccagccagag aatctggagt accggataat gctgtcagtt 1381 catggctccc agcacagtgg gatgatcgtt aatgacacag gacatgaaac tgatgagaat 1441 agagcgaagg ttgagataac gcccaattca ccaagagccg aagccaccct ggggggtttt 1501 ggaagcctag gactggattg tgaaccgagg acaggccttg acttttcaga tttgtattac 1561 ttgactatga ataacaagca ctggttggtt cacaaggagt ggttccacga cattccatta 1621 ccttggcacg ctggggcaga caccggaact ccacactgga acaacaaaga agcactggta 1681 gagttcaagg acgcacatgc caaaaggcaa actgtcgtgg ttctagggag tcaagaagga 1741 gcagttcaca cggcccttgc tggagctctg gaggctgaga tggatggtgc aaagggaagg 1801 ctgtcctctg gccacttgaa atgtcgcctg aaaatggata aacttagatt gaagggcgtg 1861 tcatactcct tgtgtaccgc agcgttcaca ttcaccaaga tcccggctga aacactgcac 1921 gggacagtca cagtggaggt acagtacgca gggacagatg gaccttgcaa ggttccagct 1981 cagatggcgg tggacatgca aactctgacc ccagttggga ggttgataac cgccaacccc 2041 gtaatcactg aaagcactga gaactctaag atgatgctgg aacttgatcc accatttggg 2101 gactcttaca ttgtcatagg agtcggggag aagaagatca cccaccactg gcacaggagt 2161 ggcagcacca ttggaaaagc atttgaagcc actgtgagag gtgccaagag aatggcagtc 2221 ttgggagata cagcctggga ctttggatca gttggaggcg ctctcaactc attgggcaag 2281 ggcatccatc aaatttttgg agcagctttc aaatcattgt ttggaggaat gtcctggttc 2341 tcacaaatcc tcattggaac gttgctgatg tggttgggtc tgaacacaaa gaatggatct 2401 atttccctca tgtgcttggc cttaggggga gtgttgatct tcttatccac agccgtctct 2461 gctgatgtgg ggtgctcggt ggacttctca aagaaggaga cgagatgcgg tacaggggtg 2521 ttcgtctata acgacgttga agcctggagg gacaggtaca agtaccatcc tgactccccc 2581 cgtagattgg cagcagcagt caagcaagcc tgggaagatg gtatctgcgg gatctcctct 2641 gtttcaagaa tggaaaacat catgtggaga tcagtagaag gggagctcaa tgcaatcctg 2701 gaagagaatg gagttcaact gacggtcgtt gtgggatctg taaaaaaccc catgtggaga 2761 ggtccacaga gattgcccgt gcctgtgaac gagctgcccc acggctggaa ggcttggggg 2821 aaatcgtact tcgttagagc agcaaagaca aataacagct ttgtcgtgga tggtgacaca 2881 ctgaaggaat gcccactcaa acatagagca tggaacagct ttcttgtgga ggatcatggg 2941 ttcggggtat ttcacactag tgtctggctc aaggttagag aagattattc attagagtgt 3001 gatccagccg ttattggaac agctgttaag ggaaaggagg ctgtacacag tgatctaggc 3061 tactggattg agagtgagaa gaatgacaca tggaggctga agagggccca tctgatcgag 3121 atgaaaacat gtgaatggcc aaagtcccac acattgtgga cagatggaat agaagagagt 3181 gatctgatca tacccaagtc tttagctggg ccactcagcc atcacaatac cagagagggc 3241 tacaggaccc aaatgaaagg gccatggcac agtgaagagc ttgaaattcg gtttgaggaa 3301 tgcccaggca ctaaggtcca cgtggaggaa acatgtggaa caagaggacc atctctgaga 3361 tcaaccactg caagcggaag ggtgatcgag gaatggtgct gcagggagtg cacaatgccc 3421 ccactgtcgt tccgggctaa agatggctgt tggtatggaa tggagataag gcccaggaaa 3481 gaaccagaaa gcaacttagt aaggtcagtg gtgactgcag gatcaactga tcacatggat 3541 cacttctccc ttggagtgct tgtgattctg ctcatggtgc aggaagggct gaagaagaga 3601 atgaccacaa agatcatcat aagcacatca atggcagtgc tggtagctat gatcctggga 3661 ggattttcaa tgagtgacct ggctaagctt gcaattttga tgggtgccac cttcgcggaa 3721 atgaacactg gaggagatgt agctcatctg gcgctgatag cggcattcaa agtcagacca 3781 gcgttgctgg tatctttcat cttcagagct aattggacac cccgtgaaag catgctgctg 3841 gccttggcct cgtgtctttt gcaaactgcg atctccgcct tggaaggcga cctgatggtt 3901 ctcatcaatg gttttgcttt ggcctggttg gcaatacgag cgatggttgt tccacgcact 3961 gataacatca ccttggcaat cctggctgct ctgacaccac tggcccgggg cacactgctt 4021 gtggcgtgga gagcaggcct tgctacttgc ggggggttta tgctcctctc tctgaaggga 4081 aaaggcagtg tgaagaagaa cttaccattt gtcatggccc tgggactaac cgctgtgagg 4141 ctggtcgacc ccatcaacgt ggtgggactg ctgttgctca caaggagtgg gaagcggagc 4201 tggcccccta gcgaagtact cacagctgtt ggcctgatat gcgcattggc tggagggttc 4261 gccaaggcag atatagagat ggctgggccc atggccgcgg tcggtctgct aattgtcagt 4321 tacgtggtct caggaaagag tgtggacatg tacattgaaa gagcaggtga catcacatgg 4381 gaaaaagatg cggaagtcac tggaaacagt ccccggctcg aygtggcgct agatgagagt 4441 ggtgatttct ccctggtgga ggatgacggt ccccccatga gagagatcat actcaaggtg 4501 gtcctgatga ccatctgtgg catgaaccca atagccatac cctttgcagc tggagcgtgg 4561 tacgtatacg tgaagactgg aaaaaggagt ggtgctctat gggatgtgcc tgctcccaag 4621 gaagtaaaaa agggggagac cacagatgga gtgtacagag taatgactcg tagactgcta 4681 ggttcaacac aagttggagt gggagttatg caagaggggg tctttcacac tatgtggcac 4741 gtcacaaaag gatccgcgct gagaagcggt gaagggagac ttgatccata ctggggagat 4801 gtcaagcagg atctggtgtc atactgtggt ccatggaagc tagatgccgc ctgggacggg 4861 cacagcgagg tgcagctctt ggccgtgccc cccggagaga gagcgaggaa catccagact 4921 ctgcccggaa tatttaagac aaaggatggg gacattggag cggttgcgct ggattaccca 4981 gcaggaactt caggatctcc aatcctagac aagtgtggga gagtgatagg actttatggc 5041 aatggggtcg tgatcaaaaa tgggagttat gttagtgcca tcacccaagg gaggagggag 5101 gaagagactc ctgttgagtg cttcgagcct tcgatgctga agaagaagca gctaactgtc 5161 ttagacttgc atcctggagc tgggaaaacc aggagagttc ttcctgaaat agtccgtgaa 5221 gctataaaaa caagactccg tactgtgatc ttagctccaa ccagggttgt cgctgctgaa 5281 atggaggaag cccttagagg gcttccagtg cgttatatga caacagcagt caatgtcacc 5341 cattctggaa cagaaatcgt cgacttaatg tgccatgcca ccttcacttc acgtctacta 5401 cagccaatca gagtccccaa ctataatctg tatattatgg atgaggccca cttcacagat 5461 ccctcaagta tagcagcaag aggatacatt tcaacaaggg ttgagatggg cgaggcggct 5521 gccatcttca tgaccgccac gccaccagga acccgtgacg catttccgga ctccaactca 5581 ccaattatgg acaccgaagt ggaagtccca gagagagcct ggagctcagg ctttgattgg 5641 gtgacggatc attctggaaa aacagtttgg tttgttccaa gcgtgaggaa cggcaatgag 5701 atcgcagctt gtctgacaaa ggctggaaaa cgggtcatac agctcagcag aaagactttt 5761 gagacagagt tccagaaaac aaaacatcaa gagtgggact ttgtcgtgac aaccgacatt 5821 tcagagatgg gcgccaactt taaagctgac cgtgtcatag attccaggag atgcctaaag 5881 ccggtcatac ttgatggcga gagagtcatt ctggctggac ccatgcctgt cacacatgcc 5941 agcgctgccc agaggagggg gcgcataggc aggaatccca acaaacctgg agatgagtat 6001 ctgtatggag gtgggtgcgc agagactgac gaagaccatg cacactggct tgaagcaaga 6061 atgctccttg acaatattta cctccaagat ggcctcatag cctcgctcta tcgacctgag 6121 gccgacaaag tagcagccat tgagggagag ttcaagctta ggacggagca aaggaagacc 6181 tttgtggaac tcatgaaaag aggagatctt cctgtttggc tggcctacca ggttgcatct 6241 gccggaatag cttacacaga tagaagatgg tgctttgatg gcacgaccaa caacaccata 6301 atggaagaca gtgtgccggc agaggtgtgg accagacacg gagagaaaag agtgctcaaa 6361 ccgaggtgga tggacgccag agtttgttca gatcatgcgg ccctgaagtc attcaaggag 6421 tttgccgctg ggaaaagagg agcggctttt ggagtgatgg aagccctggg aacactgcca 6481 ggacacatga cagagagatt ccaggaagcc attgacaacc tcgctgtgct catgcgggca 6541 gagactggaa gcaggcctta caaagccgcg gcggcccaat tgccggagac cctagagacc 6601 attatgcttt tggggttgct gggaacagtc tcgctgggaa tctttttcgt cttgatgagg 6661 aacaagggca tagggaagat gggctttgga atggtgactc ttggggccag cgcatggctc 6721 atgtggctct cggaaattga gccagccaga attgcatgtg tcctcattgt tgtgttccta 6781 ttgctggtgg tgctcatacc tgagccagaa aagcaaagat ctccccagga caaccaaatg 6841 gcaatcatca tcatggtagc agtaggtctt ctaggcttga tcaccgccaa tgaactcgga 6901 tggttggaga gaacaaagag tgacctaagc catctaatgg gaaggagaga ggagggagca 6961 accataggat tctcaatgga cattgacctg cggccagcct cagcttgggc catctatgct 7021 gccttgacaa ctttcattac cccagccgtc caacatgcag tgaccacttc atacaacaac 7081 tactccttaa tggcgatggc cacgcaagct ggagtgttgt ttggtatggg caaagggatg 7141 ccattctacg catgggactt tggagtcccg ctgctaatga taggttgcta ctcacaatta 7201 acacccctga ccctaatagt ggccatcatt ttgctcgtgg cgcactacat gtacttgatc 7261 ccagggctgc aggcagcagc tgcgcgtgct gcccagaaga gaacggcagc tggcatcatg 7321 aagaaccctg ttgtggatgg aatagtggtg actgacattg acacaatgac aattgacccc 7381 caagtggaga aaaagatggg acaggtgcta ctcatagcag tagccgtctc cagcgccata 7441 ctgtcgcgga ccgcctgggg gtggggggag gctggggccc tgatcacagc cgcaacttcc 7501 actttgtggg aaggctctcc gaacaattac tggaactcct ctacagccac ttcactgtgt 7561 aacattttta ggggaagtta cttggctgga gcttctctaa tctacacagt aacaagaaac 7621 gctggcttgg tcaagagacg tgggggtgga acaggagaga ccctgggaga gaaatggaag 7681 gcccgcttga accagatgtc ggccctggag ttctactcct acaaaaagtc aggcatcacc 7741 gaggtgtgca gagaagaggc ccgccgcgcc ctcaaggacg gtgtggcaac gggaggccat 7801 gctgtgtccc gaggaagtgc aaagctgaga tggttggtgg agcggggata cctgcagccc 7861 tatggaaagg tcattgatct tggatgtggc agagggggct ggagttacta cgccgccacc 7921 atccgcaaag ttcaagaagt gaaaggatac acaaaaggag gccctggtca tgaagaaccc 7981 gtgttggtgc aaagctatgg gtggaacata gtccgtctca agagtggggt ggacgtcttt 8041 catatggcgg ctgagccgtg tgacacgttg ctatgtgaca taggtgagtc atcatctagt 8101 cctgaagtgg aagaagcacg gacgctcaga gtcctctcca tggtggggga ttggcttgaa 8161 aaaagaccag gagccttttg tataaaagtg ttgtgcccat acaccagcac tatgatggaa 8221 accctggagc gactgcagcg taggtatggg ggaggactgg tcagagtgcc actctcccgc 8281 aactctacac atgagatgta ctgggtctct ggagcgaaaa gcaacaccat aaaaagtgtg 8341 tccaccacga gccagctcct cttggggcgc atggacgggc ctaggaggcc agtgaaatat 8401 gaggaggatg tgaatctcgg ctctggcacg cgggctgtgg taagctgcgc tgaagctccc 8461 aacatgaaga tcattggtaa ccgcattgaa aggatccgca gtgagcacgc ggaaacgtgg 8521 ttctttgacg agaaccaccc atataggaca tgggcttacc atggaagcta tgaggccccc 8581 acacaagggt cagcatcctc tctagtaaac ggggttgtca ggctcctgtc aaaaccctgg 8641 gatgtggtga ctggagtcac aggaatagcc atgaccgaca ccacaccgta tggtcagcaa 8701 agagttttca aggaaaaagt ggacactagg gtgccagacc cccaagaagg cactcgtcag 8761 gttatgagca tggtctcttc ctggttgtgg aaagagctag gcaaacacaa acggccacga 8821 gtctgtacca aagaagagtt catcaacaag gttcgtagca atgcagcatt aggggcaata 8881 tttgaagagg aaaaagagtg gaagactgca gtggaagctg tgaacgatcc aaggttctgg 8941 gctctagtgg acaaggaaag agagcaccac ctgagaggag agtgccagag ttgtgtgtac 9001 aacatgatgg gaaaaagaga aaagaaacaa ggggaatttg gaaaggccaa gggcagccgc 9061 gccatctggt atatgtggct aggggctaga tttctagagt tcgaagccct tggattcttg 9121 aacgaggatc actggatggg gagagagaac tcaggaggtg gtgttgaagg gctgggatta 9181 caaagactcg gatatgtcct agaagagatg agtcgcatac caggaggaag gatgtatgca 9241 gatgacactg ctggctggga tacccgcatc agcaggtttg atctagagaa tgaagctcta 9301 atcaccaacc aaatggagaa agggcacagg gccttggcat tggccataat caagtacaca 9361 taccaaaaca aagtggtaaa ggtccttaga ccagctgaaa aagggaaaac agttatggac 9421 attatttcga gacaagacca aagggggagc ggacaagttg tcacttacgc tcttaacaca 9481 tttaccaacc tagtggtgca actcattcgg aatatggagg ctgaggaagt tctagagatg 9541 caagacttgt ggctgctgcg gaggtcagag aaagtgacca actggttgca gagcaacgga 9601 tgggataggc tcaaacgaat ggcagtcagt ggagatgatt gcgttgtgaa gccaattgat 9661 gataggtttg cacatgccct caggttcttg aatgatatgg gaaaagttag gaaggacaca 9721 caagagtgga aaccctcaac tggatgggac aactgggaag aagttccgtt ttgctcccac 9781 cacttcaaca agctccatct caaggacggg aggtccattg tggttccctg ccgccaccaa 9841 gatgaactga ttggccgggc ccgcgtctct ccaggggcgg gatggagcat ccgggagact 9901 gcttgcctag caaaatcata tgcgcaaatg tggcagctcc tttatttcca cagaagggac 9961 ctccgactga tggccaatgc catttgttca tctgtgccag ttgactgggt tccaactggg 10021 agaactacct ggtcaatcca tggaaaggga gaatggatga ccattgaaga catgcttgtg 10081 gtgtggaaca gagtgtggat tgaggagaac gaccacatgg aagacaagac cccagttacg 10141 aaatggacag acattcccta tttgggaaaa agggaagact tgtggtgtgg atctctcata 10201 gggcacagac cgcgcaccac ctgggctgag aacattaaaa acacagtcaa catggtgcgc 10261 aggatcatag gtgaggaaga aaagtacatg gactacctat ccacccaagt ccgctacttg 10321 ggtgaagaag ggtctacacc tggagtgctg taagcaccaa tcttaatgtt gtcaggcctg 10381 ctagtcagcc acagcttggg gaaagctgtg cagcctgtga cccccccagg agaagctggg 10441 aaaccaagcc tatagtcagg ccgagaacgc catggcacgg aagaagccat gctgcctgtg 10501 agcccctcag aggacactga gtcaaaaaac cccacgcgct tggaggcgca ggatgggaaa 10561 agaaggtggc gaccttcccc acccttcaat ctggggcctg aactggagat

Sequences producing significant alignments: Select:AllNone Selected:0 AlignmentsDownloadGenBankGraphicsDistance tree of resultsShow/hide columns of the table presenting sequences producing significant alignments Sequences producing significant alignments: Select for downloading or viewing reports Description Max score Total score Query cover E value Ident Accession Select seq gb|KX838906.1| Zika virus isolate ZIKV/Aedes_aegypti/USA/2016/ZM3-7729 polyprotein gene, complete cds 18500 18500 100% 0.0 99% KX838906.1 Select seq gb|KX673530.1| Zika virus isolate PHE_semen_Guadeloupe, complete genome 18428 18428 100% 0.0 99% KX673530.1 Select seq gb|KU853013.1| Zika virus isolate Dominican Republic/2016/PD2, complete genome 18422 18422 100% 0.0 99% KU853013.1 Select seq gb|KU853012.1| Zika virus isolate Dominican Republic/2016/PD1, complete genome 18422 18422 100% 0.0 99% KU853012.1 Select seq gb|KX842449.1| Zika virus isolate ZIKV/Human/USA/2016/ZF10.UR-010 polyprotein gene, complete cds 18413 18413 100% 0.0 99% KX842449.1 Select seq gb|KX838905.1| Zika virus isolate ZIKV/Aedes_aegypti/USA/2016/ZM2-7719 polyprotein gene, complete cds 18410 18410 100% 0.0 99% KX838905.1 Select seq gb|KX838904.1| Zika virus isolate ZIKV/Aedes_aegypti/USA/2016/ZM1-7501 polyprotein gene, complete cds 18404 18404 100% 0.0 99% KX838904.1 Select seq gb|KX832731.1| Zika virus isolate ZIKV/Human/USA/2016/ZL2.SA-Hu0015 polyprotein gene, complete cds 18404 18404 100% 0.0 99% KX832731.1 Select seq gb|KX447510.1| Zika virus isolate 1_0049_PF polyprotein gene, complete cds 18332 18332 100% 0.0 99% KX447510.1 Select seq gb|KX280026.1| Zika virus isolate Paraiba_01, complete genome 18328 18328 100% 0.0 99% KX280026.1 Select seq gb|KU729217.2| Zika virus isolate BeH823339 polyprotein gene, complete cds 18328 18328 100% 0.0 99% KU729217.2 Select seq gb|KX447512.1| Zika virus isolate 1_0181_PF polyprotein gene, complete cds 18323 18323 100% 0.0 99% KX447512.1 Select seq gb|KX369547.1| Zika virus strain PF13/251013-18, complete genome 18323 18323 100% 0.0 99% KX369547.1 Select seq gb|KU509998.3| Zika virus strain Haiti/1225/2014, complete genome 18323 18323 100% 0.0 99% KU509998.3 Select seq gb|KJ776791.2| Zika virus strain H/PF/2013, complete genome 18319 18319 100% 0.0 99% KJ776791.2 Select seq gb|KX447509.1| Zika virus isolate 1_0087_PF polyprotein gene, complete cds 18319 18319 100% 0.0 99% KX447509.1 Select seq gb|KU991811.1| Zika virus isolate Brazil/2016/INMI1 polyprotein gene, complete cds 18319 18319 100% 0.0 99% KU991811.1 Select seq gb|KX447513.1| Zika virus isolate 1_0134_PF polyprotein gene, complete cds 18314 18314 100% 0.0 99% KX447513.1 Select seq gb|KX811222.1| Zika virus isolate Brazil_2015_MG, complete genome 18310 18310 100% 0.0 99% KX811222.1 Select seq gb|KX197205.1| Zika virus isolate 9, complete genome 18310 18310 100% 0.0 99% KX197205.1 Select seq gb|KX447515.1| Zika virus isolate 1_0030_PF polyprotein gene, complete cds 18310 18310 100% 0.0 99% KX447515.1 Select seq gb|KX447511.1| Zika virus isolate 1_0015_PF polyprotein gene, complete cds 18310 18310 100% 0.0 99% KX447511.1 Select seq gb|KU321639.1| Zika virus strain ZikaSPH2015, complete genome 18310 18310 100% 0.0 99% KU321639.1 Select seq gb|KX879604.1| Zika virus isolate SN089, complete genome 18305 18305 100% 0.0 99% KX879604.1 Select seq gb|KX447514.1| Zika virus isolate 1_0035_PF polyprotein gene, complete cds 18305 18305 100% 0.0 99% KX447514.1 Select seq gb|KX051563.1| Zika virus isolate Haiti/1/2016, complete genome 18305 18305 100% 0.0 99% KX051563.1 Select seq gb|KU707826.1| Zika virus isolate SSABR1, complete genome 18305 18305 100% 0.0 99% KU707826.1 Select seq gb|KU365779.1| Zika virus strain BeH819966 polyprotein gene, complete cds 18305 18305 100% 0.0 99% KU365779.1 Select seq gb|KX447516.1| Zika virus isolate 1_0111_PF polyprotein gene, complete cds 18301 18301 100% 0.0 99% KX447516.1 Select seq gb|KX262887.1| Zika virus isolate 103451, complete genome 18301 18301 100% 0.0 99% KX262887.1 Select seq gb|KU926309.1| Zika virus isolate Rio-U1, complete genome 18301 18301 100% 0.0 99% KU926309.1 Select seq gb|KU729218.1| Zika virus isolate BeH828305 polyprotein gene, complete cds 18301 18301 100% 0.0 99% KU729218.1 Select seq gb|KU527068.1| Zika virus strain Natal RGN, complete genome 18301 18301 100% 0.0 99% KU527068.1 Select seq gb|KX879603.1| Zika virus isolate SN062, complete genome 18296 18296 100% 0.0 99% KX879603.1 Select seq gb|KX197192.1| Zika virus isolate ZIKV/H.sapiens/Brazil/PE243/2015, complete genome 18296 18296 100% 0.0 99% KX197192.1 Select seq gb|KU926310.1| Zika virus isolate Rio-S1, complete genome 18296 18296 100% 0.0 99% KU926310.1 Select seq gb|KX694534.1| Zika virus strain ZIKV/Homo sapiens/HND/R103451/2015, complete genome 18292 18292 100% 0.0 99% KX694534.1 Select seq gb|KU940228.1| Zika virus isolate Bahia07, partial genome 18292 18292 100% 0.0 99% KU940228.1 Select seq gb|KU501217.1| Zika virus strain 8375 polyprotein gene, complete cds 18292 18292 100% 0.0 99% KU501217.1 Select seq gb|KU365780.1| Zika virus strain BeH815744 polyprotein gene, complete cds 18292 18292 100% 0.0 99% KU365780.1 Select seq gb|KX198135.1| Zika virus strain ZIKV/Homo sapiens/PAN/BEI-259634_V4/2016, complete genome 18287 18287 100% 0.0 99% KX198135.1 Select seq gb|KU501216.1| Zika virus strain 103344 polyprotein gene, complete cds 18287 18287 100% 0.0 99% KU501216.1 Select seq gb|KU365777.1| Zika virus strain BeH818995 polyprotein gene, complete cds 18287 18287 100% 0.0 99% KU365777.1 Select seq gb|KU758877.1| Zika virus isolate 17271 polyprotein gene, complete cds 18283 18283 100% 0.0 99% KU758877.1 Select seq gb|KX247632.1| Zika virus isolate MEX_I_7 polyprotein gene, complete cds 18283 18283 100% 0.0 99% KX247632.1 Select seq gb|KU647676.1| Zika virus strain MRS_OPY_Martinique_PaRi_2015 polyprotein gene, complete cds 18283 18283 100% 0.0 99% KU647676.1 Select seq gb|KX447517.1| Zika virus isolate 1_0038_PF polyprotein gene, complete cds 18278 18278 100% 0.0 99% KX447517.1 Select seq gb|KX247646.1| Zika virus isolate Zika virus/Homo sapiens/COL/UF-1/2016, complete genome 18278 18278 100% 0.0 99% KX247646.1 Select seq gb|KX156776.1| Zika virus strain ZIKV/Homo sapiens/PAN/CDC-259364_V1-V2/2015, complete genome 18278 18278 100% 0.0 99% KX156776.1 Select seq gb|KX856011.1| Zika virus strain ZIKV/Aedes sp./MEX_I-44/2016, complete genome 18274 18274 100% 0.0 99% KX856011.1 Select seq gb|KX520666.1| Zika virus isolate HS-2015-BA-01 polyprotein gene, complete cds 18274 18274 100% 0.0 99% KX520666.1 Select seq gb|KX446951.1| Zika virus strain ZIKV/Aedes.sp/MEX/MEX_I-7/2016, complete genome 18274 18274 100% 0.0 99% KX446951.1 Select seq gb|KX156774.1| Zika virus strain ZIKV/Homo sapiens/PAN/CDC-259359_V1-V3/2015, complete genome 18274 18274 100% 0.0 99% KX156774.1 Select seq gb|KU497555.1| Zika virus isolate Brazil-ZKV2015, complete genome 18274 18274 99% 0.0 99% KU497555.1 Select seq gb|KU501215.1| Zika virus strain PRVABC59, complete genome 18274 18274 100% 0.0 99% KU501215.1 Select seq gb|KU365778.1| Zika virus strain BeH819015 polyprotein gene, complete cds 18274 18274 100% 0.0 99% KU365778.1 Select seq gb|KU312312.1| Zika virus isolate Z1106033 polyprotein gene, complete cds 18274 18274 100% 0.0 99% KU312312.1 Select seq gb|KU820897.5| Zika virus isolate FLR polyprotein gene, complete cds 18269 18269 100% 0.0 99% KU820897.5 Select seq gb|KX601168.1| Zika virus strain ZIKV/Homo Sapiens/PRI/PRVABC59/2015, complete genome 18269 18269 100% 0.0 99% KX601168.1 Select seq gb|KX446950.1| Zika virus strain ZIKV/Aedes.sp/MEX/MEX_2-81/2016, complete genome 18269 18269 100% 0.0 99% KX446950.1 Select seq gb|KX087101.2| Zika virus strain ZIKV/Homo sapiens/PRI/PRVABC59/2015, complete genome 18269 18269 100% 0.0 99% KX087101.2 Select seq gb|KX156775.1| Zika virus strain ZIKV/Homo sapiens/PAN/CDC-259249_V1-V3/2015, complete genome 18269 18269 100% 0.0 99% KX156775.1 Select seq gb|KX087102.1| Zika virus strain ZIKV/Homo sapiens/COL/FLR/2015, complete genome 18269 18269 100% 0.0 99% KX087102.1 Select seq gb|KX377337.1| Zika virus strain PRVABC-59, complete genome 18265 18265 100% 0.0 99% KX377337.1 Select seq gb|KU937936.1| Zika virus isolate ZIKVNL00013 polyprotein gene, complete cds 18265 18265 100% 0.0 99% KU937936.1 Select seq gb|KU922960.1| Zika virus isolate MEX/InDRE/Sm/2016, complete genome 18265 18265 100% 0.0 99% KU922960.1 Select seq gb|KX806557.1| Zika virus isolate TS17-2016, complete genome 18260 18260 100% 0.0 99% KX806557.1 Select seq gb|KX548902.1| Zika virus isolate ZIKV/COL/FCC00093/2015 polyprotein gene, complete cds 18260 18260 100% 0.0 99% KX548902.1 Select seq gb|KU870645.1| Zika virus isolate FB-GWUH-2016, complete genome 18260 18260 100% 0.0 99% KU870645.1 Select seq gb|KU922923.1| Zika virus isolate MEX/InDRE/Lm/2016, complete genome 18260 18260 100% 0.0 99% KU922923.1 Select seq gb|KX766029.1| Zika virus isolate R116265, complete genome 18256 18256 100% 0.0 99% KX766029.1 Select seq gb|KX702400.1| Zika virus strain Zika virus/Homo sapiens/VEN/UF-1/2016, complete genome 18251 18251 100% 0.0 99% KX702400.1 Select seq gb|KU820898.1| Zika virus isolate GZ01 polyprotein gene, complete cds 18247 18247 100% 0.0 99% KU820898.1 Select seq gb|KX056898.1| Zika virus isolate Zika virus/GZ02/2016 polyprotein gene, complete cds 18242 18242 100% 0.0 99% KX056898.1 Select seq gb|KU955590.1| Zika virus isolate Z16019 polyprotein gene, complete cds 18242 18242 100% 0.0 99% KU955590.1 Select seq gb|KX766028.1| Zika virus isolate R114916, complete genome 18240 18240 100% 0.0 99% KX766028.1 Select seq gb|KU740184.2| Zika virus isolate GD01 polyprotein gene, complete cds 18238 18238 100% 0.0 99% KU740184.2 Select seq gb|KU761564.1| Zika virus isolate GDZ16001 polyprotein gene, complete cds 18238 18238 100% 0.0 99% KU761564.1 Select seq gb|KX117076.1| Zika virus isolate Zhejiang04, complete genome 18229 18229 100% 0.0 99% KX117076.1 Select seq gb|KX185891.1| Zika virus isolate Zika virus/CN/SZ02/2016 polyprotein gene, complete cds 18220 18220 100% 0.0 99% KX185891.1 Select seq gb|KU963796.1| Zika virus isolate SZ-WIV01 polyprotein gene, complete cds 18220 18220 100% 0.0 99% KU963796.1 Select seq gb|KX253996.1| Zika virus isolate ZKC2/2016, complete genome 18215 18215 100% 0.0 99% KX253996.1 Select seq gb|KU955589.1| Zika virus isolate Z16006 polyprotein gene, complete cds 18215 18215 100% 0.0 99% KU955589.1 Select seq gb|KU820899.2| Zika virus isolate ZJ03, complete genome 18215 18215 100% 0.0 99% KU820899.2 Select seq gb|KX266255.1| Zika virus isolate ZIKV_SMGC-1, complete genome 18211 18211 100% 0.0 99% KX266255.1 Select seq gb|KU866423.2| Zika virus isolate Zika virus/SZ01/2016/China polyprotein gene, complete cds 18211 18211 100% 0.0 99% KU866423.2 Select seq gb|KU940224.1| Zika virus isolate Bahia09, partial genome 18197 18197 99% 0.0 99% KU940224.1 Select seq gb|KU744693.1| Zika virus isolate VE_Ganxian, complete genome 18080 18080 100% 0.0 99% KU744693.1 Select seq gb|KX827309.1| Zika virus isolate ZKA-16-291 polyprotein gene, complete cds 18071 18071 100% 0.0 99% KX827309.1 Select seq gb|KX813683.1| Zika virus isolate ZKA-16-097 polyprotein gene, complete cds 18058 18058 100% 0.0 99% KX813683.1 Select seq gb|KU681081.3| Zika virus isolate Zika virus/H.sapiens-tc/THA/2014/SV0127- 14, complete genome 18013 18013 100% 0.0 99% KU681081.3 Select seq gb|KX694532.1| Zika virus strain ZIKV/Homo sapiens/THA/PLCal_ZV/2013, complete genome 17890 17890 100% 0.0 99% KX694532.1 Select seq gb|KU955593.1| Zika virus isolate Zika virus/H.sapiens-tc/KHM/2010/FSS13025, complete genome 17697 17697 100% 0.0 98% KU955593.1 Select seq gb|JN860885.1| Zika virus isolate FSS13025 polyprotein gene, partial cds 17695 17695 99% 0.0 98% JN860885.1 Select seq gb|KF993678.1| Zika virus strain PLCal_ZV from Canada polyprotein gene, partial cds 17659 17659 98% 0.0 99% KF993678.1 Select seq gb|EU545988.1| Zika virus polyprotein gene, complete cds 17551 17551 100% 0.0 98% EU545988.1 Select seq gb|KU681082.3| Zika virus isolate Zika virus/H.sapiens-tc/PHL/2012/CPC-0740, complete genome 17403 17403 100% 0.0 98% KU681082.3 Select seq gb|KX601167.1| Zika virus strain ZIKV/Aedes sp./MYS/P6-740/1966, complete genome 16384 16384 100% 0.0 95% KX601167.1 Select seq gb|HQ234499.1| Zika virus isolate P6-740 polyprotein gene, partial cds 16377 16377 99% 0.0 95% HQ234499.1 Select seq gb|KX694533.1| Zika virus strain ZIKV/Aedes aegypti/MYS/P6-740/1966, complete genome 16375 16375 100% 0.0 95% KX694533.1

LOCUS KX922705 10609 bp RNA linear VRL 05-OCT-2016 DEFINITION Zika virus isolate ZIKV/Homo_sapiens/USA/2016/FL032U polyprotein gene, complete cds. ACCESSION KX922705 VERSION KX922705.1 GI:1071930514 DBLINK BioProject: PRJNA342539 BioSample: SAMN05853064 KEYWORDS . SOURCE Zika virus ORGANISM Zika virus Viruses; ssRNA viruses; ssRNA positive-strand viruses, no DNA stage; Flaviviridae; Flavivirus. REFERENCE 1 (bases 1 to 10609) AUTHORS Grubaugh,N., Tan,A., Gangavarupu,K., Oliveira,G., Robles-Sikisaka,R., Cone,M., Kopp,E., Hogan,K., Cannons,A., Michael,S., Isern,S. and Andersen,K. TITLE Zika virus sequences from Florida, USA, 2016 JOURNAL Unpublished REFERENCE 2 (bases 1 to 10609) AUTHORS Grubaugh,N., Tan,A., Gangavarupu,K., Oliveira,G., Robles-Sikisaka,R., Cone,M., Kopp,E., Hogan,K., Cannons,A., Michael,S., Isern,S. and Andersen,K. TITLE Direct Submission JOURNAL Submitted (29-SEP-2016) Department of Immunology and Microbial Science, The Scripps Research Institute, 10550 North Torrey Pines Road, IMM-210, La Jolla, CA 92037, USA COMMENT ##Assembly-Data-START## Assembly Method :: NovoAlign v. V3.04 Sequencing Technology :: Illumina ##Assembly-Data-END## FEATURES Location/Qualifiers source 1..10609 /organism="Zika virus" /mol_type="genomic RNA" /isolate="ZIKV/Homo_sapiens/USA/2016/FL032U" /isolation_source="urine" /host="Homo sapiens" /db_xref="taxon:64320" /country="USA: Miami, Florida" /collection_date="29-Jul-2016" CDS 81..10352 /codon_start=1 /product="polyprotein" /protein_id="AOS90222.1" /db_xref="GI:1071930515" /translation="MKNPKKKSGGFRIVNMLKRGVARVSPFGGLKRLPAGLLLGHGPI RMVLAILAFLRFTAIKPSLGLINRWGSVGKKEAMEIIKKFKKDLAAMLRIINARKEKK RRGADTSVGIVGLLLTTAMAAEVTRRGSAYYMYLDRNDAGEAISFPTTLGMNKCYIQI MDLGHMCDATMSYECPMLDEGVEPDDVDCWCNTTSTWVVYGTCHHKKGEARRSRRAVT LPSHSTRKLQTRSQTWLESREYTKHLIRVENWIFRNPGFALAAAAIAWLLGSSTSQKV IYLVMILLIAPAYSIRCIGVSNRDFVEGMSGGTWVDVVLEHGGCVTVMAQDKPTVDIE LVTTTVSNMAEVRSYCYEASISDMASDSRCPTQGEAYLDKQSDTQYVCKRTLVDRGWG NGCGLFGKGSLVTCAKFACSKKMTGKSIQPENLEYRIMLSVHGSQHSGMIVNDTGHET DENRAKVEITPNSPRAEATLGGFGSLGLDCEPRTGLDFSDLYYLTMNNKHWLVHKEWF HDIPLPWHAGADTGTPHWNNKEALVEFKDAHAKRQTVVVLGSQEGAVHTALAGALEAE MDGAKGRLSSGHLKCRLKMDKLRLKGVSYSLCTAAFTFTKIPAETLHGTVTVEVQYAG TDGPCKVPAQMAVDMQTLTPVGRLITANPVITESTENSKMMLELDPPFGDSYIVIGVG EKKITHHWHRSGSTIGKAFEATVRGAKRMAVLGDTAWDFGSVGGALNSLGKGIHQIFG AAFKSLFGGMSWFSQILIGTLLMWLGLNTKNGSISLMCLALGGVLIFLSTAVSADVGC SVDFSKKETRCGTGVFVYNDVEAWRDRYKYHPDSPRRLAAAVKQAWEDGICGISSVSR MENIMWRSVEGELNAILEENGVQLTVVVGSVKNPMWRGPQRLPVPVNELPHGWKAWGK SYFVRAAKTNNSFVVDGDTLKECPLKHRAWNSFLVEDHGFGVFHTSVWLKVREDYSLE CDPAVIGTAVKGKEAVHSDLGYWIESEKNDTWRLKRAHLIEMKTCEWPKSHTLWTDGI EESDLIIPKSLAGPLSHHNTREGYRTQMKGPWHSEELEIRFEECPGTKVHVEETCGTR GPSLRSTTASGRVIEEWCCRECTMPPLSFRAKDGCWYGMEIRPRKEPESNLVRSVVTA GSTDHMDHFSLGVLVILLMVQEGLKKRMTTKIIISTSMAVLVAMILGGFSMSDLAKLA ILMGATFAEMNTGGDVAHLALIAAFKVRPALLVSFIFRANWTPRESMLLALASCLLQT AISALEGDLMVLINGFALAWLAIRAMVVPRTDNITLAILAALTPLARGTLLVAWRAGL ATCGGFMLLSLKGKGSVKKNLPFVMALGLTAVRLVDPINVVGLLLLTRSGKRSWPPSE VLTAVGLICALAGGFAKADIEMAGPMAAVGLLIVSYVVSGKSVDMYIERAGDITWEKD AEVTGNSPRLDVALDESGDFSLVEDDGPPMREIILKVVLMTICGMNPIAIPFAAGAWY VYVKTGKRSGALWDVPAPKEVKKGETTDGVYRVMTRRLLGSTQVGVGVMQEGVFHTMW HVTKGSALRSGEGRLDPYWGDVKQDLVSYCGPWKLDAAWDGHSEVQLLAVPPGERARN IQTLPGIFKTKDGDIGAVALDYPAGTSGSPILDKCGRVIGLYGNGVVIKNGSYVSAIT QGRREEETPVECFEPSMLKKKQLTVLDLHPGAGKTRRVLPEIVREAIKTRLRTVILAP TRVVAAEMEEALRGLPVRYMTTAVNVTHSGTEIVDLMCHATFTSRLLQPIRVPNYNLY IMDEAHFTDPSSIAARGYISTRVEMGEAAAIFMTATPPGTRDAFPDSNSPIMDTEVEV PERAWSSGFDWVTDHSGKTVWFVPSVRNGNEIAACLTKAGKRVIQLSRKTFETEFQKT KHQEWDFVVTTDISEMGANFKADRVIDSRRCLKPVILDGERVILAGPMPVTHASAAQR RGRIGRNPNKPGDEYLYGGGCAETDEDHAHWLEARMLLDNIYLQDGLIASLYRPEADK VAAIEGEFKLRTEQRKTFVELMKRGDLPVWLAYQVASAGITYTDRRWCFDGTTNNTIM EDSVPAEVWTRHGEKRVLKPRWMDARVCSDHAALKSFKEFAAGKRGAAFGVMEALGTL PGHMTERFQEAIDNLAVLMRAETGSRPYKAAAAQLPETLETIMLLGLLGTVSLGIFFV LMRNKGIGKMGFGMVTLGASAWLMWLSEIEPARIACVLIVVFLLLVVLIPEPEKQRSP QDNQMAIIIMVAVGLLGLITANELGWLERTKSDLSHLMGRREEGATIGFSMDIDLRPA SAWAIYAALTTFITPAVQHAVTTSYNNYSLMAMATQAGVLFGMGKGMPFYAWDFGVPL LMIGCYSQLTPLTLIVAIILLVAHYMYLIPGLQAAAARAAQKRTAAGIMKNPVVDGIV VTDIDTMTIDPQVEKKMGQVLLIAVAVSSAILSRTAWGWGEAGALITAATSTLWEGSP NKYWNSSTATSLCNIFRGSYLAGASLIYTVTRNAGLVKRRGGGTGETLGEKWKARLNQ MSALEFYSYKKSGITEVCREEARRALKDGVATGGHAVSRGSAKLRWLVERGYLQPYGK VIDLGCGRGGWSYYAATIRKVQEVKGYTKGGPGHEEPVLVQSYGWNIVRLKSGVDVFH MAAEPCDTLLCDIGESSSSPEVEEARTLRVLSMVGDWLEKRPGAFCIKVLCPYTSTMM ETLERLQRRYGGGLVRVPLSRNSTHEMYWVSGAKSNTIKSVSTTSQLLLGRMDGPRRP VKYEEDVNLGSGTRAVVSCAEAPNMKIIGNRIERIRSEHAETWFFDENHPYRTWAYHG SYEAPTQGSASSLVNGVVRLLSKPWDVVTGVTGIAMTDTTPYGQQRVFKEKVDTRVPD PQEGTRQVMSMVSSWLWKELGKHKRPRVCTKEEFINKVRSNAALGAIFEEEKEWKTAV EAVNDPRFWALVDKEREHHLRGECQSCVYNMMGKREKKQGEFGKAKGSRAIWYMWLGA RFLEFEALGFLNEDHWMGRENSGGGVEGLGLQRLGYVLEEMSRIPGGRMYADDTAGWD TRISRFDLENEALITNQMEKGHRALALAIIKYTYQNKVVKVLRPAEKGKTVMDIISRQ DQRGSGQVVTYALNTFTNLVVQLIRNMEAEEVLEMQDLWLLRRSEKVTNWLQSNGWDR LKRMAVSGDDCVVKPIDDRFAHALRFLNDMGKVRKDTQEWKPSTGWDNWEEVPFCSHH FNKLHLKDGRSIVVPCRHQDELIGRARVSPGAGWSIRETACLAKSYAQMWQLLYFHRR DLRLMANAICSSVPVDWVPTGRTTWSIHGKGEWMTIEDMLVVWNRVWIEENDHMEDKT PVTKWTDIPYLGKREDLWCGSLIGHRPRTTWAENIKNTVNMVRRIIGEEEKYMDYLST QVRYLGEEGSTPGVL" ORIGIN 1 cgacagttcg agtttgaagc gaaagctagc aacagtatca acaggtttta ttttggattt 61 ggaaacgaga gtttctggtc atgaaaaacc caaaaaagaa atccggagga ttccggattg 121 tcaatatgct aaaacgcgga gtagcccgtg tgagcccctt tgggggcttg aagaggctgc 181 cagccggact tctgctgggt catgggccca tcaggatggt cttggcgatt ctagcctttt 241 tgagattcac ggcaatcaag ccatcactgg gtctcatcaa tagatggggt tcagtgggga 301 aaaaagaggc tatggaaata ataaagaagt tcaagaaaga tctggctgcc atgctgagaa 361 taatcaatgc taggaaggag aagaagagac gaggcgcaga tactagtgtc ggaattgttg 421 gcctcctgct gaccacagct atggcagcgg aggtcactag acgtgggagt gcatactaca 481 tgtacttgga cagaaacgat gctggggagg ccatatcttt tccaaccaca ttggggatga 541 ataagtgtta tatacagatc atggatcttg gacacatgtg tgatgccacc atgagctatg 601 aatgccctat gctggatgag ggggtggaac cagatgacgt cgattgttgg tgcaacacga 661 cgtcaacttg ggttgtgtac ggaacctgcc atcacaaaaa aggtgaagca cggagatcta 721 gaagagctgt gacgctcccc tcccattcca ctaggaagct gcaaacgcgg tcgcaaacct 781 ggttggaatc aagagaatac acaaagcact tgattagagt cgaaaattgg atattcagga 841 accctggctt cgcgttagca gcagctgcca tcgcttggct tttgggaagc tcaacgagcc 901 aaaaagtcat atacttggtc atgatactgc tgattgcccc ggcatacagc atcaggtgca 961 taggagtcag caatagggac tttgtggaag gtatgtcagg tgggacttgg gttgatgttg 1021 tcttggaaca tggaggttgt gtcaccgtaa tggcacagga caaaccgact gtcgacatag 1081 agctggttac aacaacagtc agcaacatgg cggaggtaag atcctactgc tatgaggcat 1141 caatatcaga catggcttcg gacagccgct gcccaacaca aggtgaagcc taccttgaca 1201 agcaatcaga cactcaatat gtctgcaaaa gaacgttagt ggacagaggc tggggaaatg 1261 gatgtggact ttttggcaaa gggagcctgg tgacatgcgc taagtttgca tgctccaaga 1321 aaatgaccgg gaagagcatc cagccagaga atctggagta ccggataatg ctgtcagttc 1381 atggctccca gcacagtggg atgatcgtta atgacacagg acatgaaact gatgagaata 1441 gagcgaaggt tgagataacg cccaattcac caagagccga agccaccctg gggggttttg 1501 gaagcctagg acttgattgt gaaccgagga caggccttga cttctcagat ttgtattact 1561 tgactatgaa taacaagcac tggttggttc acaaggagtg gttccacgac attccattac 1621 cttggcacgc tggggcagac accggaactc cacactggaa caacaaagaa gcactggtag 1681 agttcaagga cgcacatgcc aaaaggcaaa ctgtcgtggt tctagggagt caagaaggag 1741 cagttcacac ggcccttgct ggagctctgg aggctgagat ggatggtgca aagggaaggc 1801 tgtcctctgg ccacttgaaa tgtcgcctga aaatggataa acttagattg aagggcgtgt 1861 catactcctt gtgtaccgca gcgttcacat tcaccaagat cccggctgaa acactgcacg 1921 ggacagtcac agtggaggta cagtacgcag ggacagatgg accttgcaag gttccagctc 1981 agatggcggt ggacatgcaa actctgaccc cagttgggag gttgataacc gccaaccccg 2041 taatcactga aagcactgag aactctaaga tgatgctgga acttgatcca ccatttgggg 2101 actcttacat tgtcatagga gtcggggaga agaagatcac ccaccactgg cacaggagtg 2161 gcagcaccat tggaaaagca tttgaagcca ctgtgagagg tgccaagaga atggcagtct 2221 tgggagacac agcctgggac tttggatcag ttggaggcgc tctcaactca ttgggcaagg 2281 gcatccatca aatttttgga gcagctttca aatcattgtt tggaggaatg tcctggttct 2341 cacaaatcct cattggaacg ttgctgatgt ggttgggtct gaacacaaag aatggatcta 2401 tttccctcat gtgcttggcc ttagggggag tgctgatctt cttatccaca gccgtctctg 2461 ctgatgtggg gtgctcggtg gacttctcaa agaaggagac gagatgcggt acaggggtgt 2521 tcgtctataa cgacgttgaa gcctggaggg acaggtacaa gtaccatcct gactcccccc 2581 gtagattggc agcagcagtc aagcaagcct gggaagatgg tatctgcggg atctcctctg 2641 tttcaagaat ggaaaacatc atgtggagat cagtagaagg ggagctcaat gcaatcctgg 2701 aagagaatgg agttcaactg acggtcgttg tgggatctgt aaaaaacccc atgtggagag 2761 gtccacagag attgcccgtg cctgtgaacg agctgcccca cggctggaag gcttggggga 2821 aatcgtactt cgttagagca gcaaagacaa ataacagctt tgtcgtggat ggtgacacac 2881 tgaaggaatg cccactcaaa catagagcat ggaacagctt tcttgtggag gatcatgggt 2941 tcggggtatt ccacactagt gtctggctca aggttagaga agattattca ttagagtgtg 3001 atccagccgt tattggaaca gctgttaagg gaaaggaggc tgtacacagt gatctaggct 3061 actggattga gagtgagaag aatgacacat ggaggctgaa gagggcccat ctgatcgaga 3121 tgaaaacatg tgaatggcca aagtcccaca cattgtggac agatggaata gaagagagtg 3181 atctgatcat acccaagtct ttagctgggc cactcagcca tcacaatacc agagagggct 3241 acaggaccca aatgaaaggg ccatggcaca gtgaagagct tgaaattcgg tttgaggaat 3301 gcccaggcac taaggtccac gtggaggaaa catgtggaac aagaggacca tctctgagat 3361 caaccactgc aagcggaagg gtgatcgagg aatggtgctg cagggagtgc acaatgcccc 3421 cactgtcgtt ccgggctaaa gatggctgtt ggtatggaat ggagataagg cccaggaaag 3481 aaccagaaag caacttagta aggtcagtgg tgactgcagg atcaactgat cacatggatc 3541 acttctccct tggagtgctt gtgattctgc tcatggtgca ggaagggctg aagaagagaa 3601 tgaccacaaa gatcatcata agcacatcaa tggcagtgct ggtagctatg atcctgggag 3661 gattttcaat gagtgacctg gctaagcttg caattttgat gggtgccacc ttcgcggaaa 3721 tgaacactgg aggagatgta gctcatctgg cgctgatagc ggcattcaaa gtcagaccag 3781 cgttgctggt atctttcatc ttcagagcta attggacacc ccgtgaaagc atgctgctgg 3841 ccttggcctc gtgtcttttg caaactgcga tctccgcctt ggaaggcgac ctgatggttc 3901 tcatcaatgg ttttgctttg gcctggttgg caatacgagc gatggttgtt ccacgcactg 3961 ataacatcac cttggcaatc ctggctgctc tgacaccact ggcccggggc acactgcttg 4021 tggcgtggag agcaggcctt gctacttgcg gggggtttat gctcctctct ctgaagggaa 4081 aaggcagtgt gaagaagaac ttaccatttg tcatggccct gggactaacc gctgtgagac 4141 tggtcgaccc catcaacgtg gtgggactgc tgttgctcac aaggagtggg aagcggagct 4201 ggccccctag cgaagtactc acagctgttg gcctgatatg cgcattggct ggagggttcg 4261 ccaaggcaga tatagagatg gctgggccca tggccgcggt cggtctgcta attgtcagtt 4321 acgtggtctc aggaaagagt gtggacatgt acattgaaag agcaggtgac atcacatggg 4381 aaaaagatgc ggaagtcact ggaaacagtc cccggctcga tgtggcgcta gatgagagtg 4441 gtgatttctc cctggtggag gatgacggtc cccccatgag agagatcata ctcaaggtgg 4501 tcctgatgac catctgtggc atgaacccaa tagccatacc ctttgcagct ggagcgtggt 4561 acgtatacgt gaagactgga aaaaggagtg gtgctctatg ggatgtgcct gctcccaagg 4621 aagtaaaaaa gggggagacc acagatggag tgtacagagt aatgactcgt agactgctag 4681 gttcaacaca agttggagtg ggagttatgc aagagggggt ctttcacact atgtggcacg 4741 tcacaaaagg atccgcgctg agaagcggtg aagggagact tgatccatac tggggagatg 4801 tcaagcagga tctggtgtca tactgtggtc catggaagct agatgccgcc tgggacgggc 4861 acagcgaggt gcagctcttg gccgtgcccc ccggagagag agcgaggaac atccagactc 4921 tgcccggaat atttaagaca aaggatgggg acattggagc ggttgcgctg gattacccag 4981 caggaacttc aggatctcca atcctagaca agtgtgggag agtgatagga ctttatggca 5041 atggggtcgt gatcaaaaat gggagttatg ttagtgccat cacccaaggg aggagggagg 5101 aagagactcc tgttgagtgc ttcgagcctt cgatgctgaa gaagaagcag ctaactgtct 5161 tagacttgca ccctggagct gggaaaacca ggagagttct tcctgaaata gtccgtgaag 5221 ctataaaaac aagactccgt actgtgatct tagctccaac cagggttgtc gctgctgaaa 5281 tggaggargc ccttagaggg cttccagtgc gttatatgac aacagcagtc aatgtcaccc 5341 attctgggac agaaatcgtt gacttaatgt gccatgccac cttcacttca cgtctactac 5401 agccaatcag agtccccaac tataatctgt atattatgga tgaggcccac ttcacagatc 5461 cctcaagtat agcagcaaga ggatacattt caacaagggt tgagatgggc gaggcggctg 5521 ccatcttcat gaccgccacg ccaccaggaa cccgtgacgc atttccggac tccaactcac 5581 caattatgga caccgaagtg gaagtcccag agagagcctg gagctcaggc tttgattggg 5641 tgacggatca ttctggaaaa acagtttggt ttgttccaag cgtgaggaac ggcaatgaga 5701 tcgcagcttg tctgacaaag gctggaaaac gggtcataca gctcagcaga aagacttttg 5761 agacagagtt ccagaaaaca aaacatcaag agtgggactt tgtcgtgaca accgacattt 5821 cagagatggg cgccaacttt aaagctgacc gtgtcataga ttccaggaga tgcctaaagc 5881 cggtcatact tgatggcgag agagtcattc tggctggacc catgcctgtc acacatgcca 5941 gcgctgccca gaggaggggg cgcataggca ggaatcccaa caaacctgga gatgagtatc 6001 tgtatggagg tgggtgcgca gagactgacg aagaccatgc acactggctt gaagcaagaa 6061 tgctccttga caatatttac ctccaagatg gcctcatagc ctcgctctat cgacctgagg 6121 ccgacaaagt agcagccatt gagggagagt tcaagcttag gacggagcaa aggaagacct 6181 ttgtggaact catgaaaaga ggagatcttc ctgtttggct ggcctatcag gttgcatctg 6241 ccggaataac ttacacagat agaagatggt gctttgatgg cacgaccaac aacaccataa 6301 tggaagacag tgtgccggca gaggtgtgga ccagacacgg agagaaaaga gtgctcaaac 6361 cgaggtggat ggacgccaga gtttgttcag atcatgcggc cctgaagtca ttcaaggagt 6421 ttgccgctgg gaaaagagga gcggcttttg gagtgatgga agccctggga acactgccag 6481 gacacatgac agagagattc caggaagcca ttgacaacct cgctgtgctc atgcgggcag 6541 agactggaag caggccttac aaagccgcgg cggcccaatt gccggagacc ctagagacca 6601 ttatgctttt ggggttgctg ggaacagtct cgctgggaat ctttttcgtc ttgatgagga 6661 acaagggcat agggaagatg ggctttggaa tggtgactct tggggccagc gcatggctca 6721 tgtggctctc ggaaattgag ccagccagaa ttgcatgtgt cctcattgtt gtgttcctat 6781 tgctggtggt gctcatacct gagccagaaa agcaaagatc tccccaggac aaccaaatgg 6841 caatcatcat catggtagca gtaggtcttc tgggcttgat caccgccaat gaactcggat 6901 ggttggagag aacaaagagt gacctaagcc atctaatggg aaggagagag gagggagcaa 6961 ccataggatt ctcaatggac attgacctgc ggccagcctc agcttgggcc atctatgctg 7021 ccttgacaac tttcattacc ccagccgtcc aacatgcagt gaccacttca tacaacaact 7081 actccttaat ggcgatggcc acgcaagctg gagtgttgtt tggtatgggc aaagggatgc 7141 cattctacgc atgggacttt ggagtcccgc tgctaatgat aggttgctac tcacaattaa 7201 cacccctgac cctaatagtg gccatcattt tgctcgtggc gcactacatg tacttgatcc 7261 cagggctgca ggcagcagct gcgcgtgctg cccagaagag aacggcagct ggcatcatga 7321 agaaccctgt tgtggatgga atagtggtga ctgacattga cacaatgaca attgaccccc 7381 aagtggagaa aaagatggga caggtgctac tcatagcagt agccgtctcc agcgccatac 7441 tgtcgcggac cgcctggggg tggggggagg ctggggccct gatcacagcc gcaacttcca 7501 ctttgtggga aggctctccg aacaagtact ggaactcctc tacagccact tcactgtgta 7561 acatttttag ggggagttac ttggctggag cttctctaat ctacacagta acaagaaacg 7621 ctggcttggt caagagacgt gggggtggaa caggagagac cctgggagag aaatggaagg 7681 cccgcttgaa ccagatgtcg gccctggagt tctactccta caaaaagtca ggcatcaccg 7741 aggtgtgcag agaagaggcc cgccgcgccc tcaaggacgg tgtggcaacg ggaggccatg 7801 ctgtgtcccg aggaagtgca aagctgagat ggttggtgga gcggggatac ctgcagccct 7861 atggaaaggt cattgatctt ggatgtggca gagggggctg gagttactac gccgccacca 7921 tccgcaaagt tcaagaagtg aaaggataca caaaaggagg ccctggtcat gaagaacctg 7981 tgttggtgca aagctatggg tggaacatag tccgtctcaa gagtggggtg gacgtctttc 8041 atatggcggc tgagccgtgt gacacgttgc tgtgtgacat aggtgagtca tcatctagtc 8101 ctgaagtgga agaagcacgg acgctcagag tcctctccat ggtgggggat tggcttgaaa 8161 aaagaccagg agccttttgt ataaaagtgt tgtgcccata caccagcact atgatggaaa 8221 ccttggagcg gctgcagcgt aggtatgggg gaggactggt cagagtgcca ctctcccgca 8281 actctacaca tgagatgtac tgggtctctg gagcgaaaag caacaccata aaaagtgtgt 8341 ccaccacgag ccagctcctc ttggggcgca tggacgggcc taggaggcca gtgaaatatg 8401 aggaggatgt gaatctcggc tctggcacgc gggctgtggt aagctgcgct gaagctccca 8461 acatgaagat cattggtaac cgcattgaaa ggatccgcag tgagcacgcg gaaacgtggt 8521 tctttgacga gaaccaccca tataggacat gggcttacca tggaagctat gaggccccta 8581 cacaagggtc agcatcctct ctagtaaacg gggttgtcag gctcctgtca aaaccctggg 8641 atgtggtgac tggagtcaca ggaatagcca tgaccgacac cacaccgtat ggtcagcaaa 8701 gagttttcaa ggaaaaagtg gacactaggg tgccagaccc ccaagaaggc actcgtcagg 8761 ttatgagcat ggtctcttcc tggttgtgga aagagctagg caaacacaaa cggccacgag 8821 tctgcaccaa agaagagttc atcaacaagg ttcgtagcaa tgcagcatta ggggcaatat 8881 ttgaagagga aaaagagtgg aagactgcag tggaagctgt gaacgatcca aggttctggg 8941 ctctagtgga caaggaaaga gagcaccacc tgagaggaga gtgccagagt tgtgtgtaca 9001 acatgatggg aaaaagagaa aagaaacaag gggaatttgg aaaggccaag ggcagccgcg 9061 ccatctggta tatgtggcta ggggctagat ttctagagtt cgaagccctt ggattcttga 9121 acgaggatca ctggatgggg agagagaact caggaggtgg tgttgaaggg ctgggattac 9181 aaagactcgg atatgtccta gaagagatga gtcgcatacc aggaggaagg atgtatgcag 9241 atgacactgc tggctgggat acccgcatca gcaggtttga tctagagaat gaagctctaa 9301 tcaccaacca aatggagaag gggcacaggg ccttggcatt ggccataatc aagtacacat 9361 accaaaataa agtggtaaag gtccttagac cagctgaaaa agggaaaaca gttatggaca 9421 ttatttcgag acaagaccaa agggggagcg gacaagttgt cacttacgct cttaacacat 9481 ttaccaacct agtggtgcaa ctcattcgga atatggaggc tgaggaagtt ctagagatgc 9541 aagacttgtg gctgctgcgg aggtcagaga aagtgaccaa ctggttgcag agcaacggat 9601 gggataggct caaacgaatg gcagtcagtg gagatgattg cgttgtgaag ccaattgatg 9661 ataggtttgc acatgccctc aggttcttga atgatatggg aaaagttagg aaggacacac 9721 aagagtggaa accctcaact ggatgggaca actgggaaga agttccgttt tgctcccacc 9781 acttcaacaa gctccatctc aaggacggga ggtccattgt ggttccctgc cgccaccaag 9841 atgaactgat tggccgggcc cgcgtctctc caggggcggg atggagcatc cgggagactg 9901 cttgcctagc aaaatcatat gcgcaaatgt ggcagctcct ttatttccac agaagggacc 9961 tccgactgat ggccaatgcc atttgttcat ctgtgccagt tgactgggtt ccaactggga 10021 gaactacctg gtcaatccat ggaaagggag aatggatgac cattgaagac atgcttgtgg 10081 tgtggaacag agtgtggatt gaggagaacg accacatgga agacaagacc ccagttacga 10141 aatggacaga cattccctat ttgggaaaaa gggaagactt gtggtgtgga tctctcatag 10201 ggcacagacc gcgcaccacc tgggctgaga acattaaaaa cacagtcaac atggtgcgca 10261 ggatcatagg tgaggaagaa aagtacatgg actacctatc cacccaagtt cgctacttgg 10321 gtgaagaagg gtctacacct ggagtgctgt aagcaccaat cttaatgttg tcaggcctgc 10381 tagtcagcca cagcttgggg aaagctgtgc agcctgtgac ccccccagga gaagctggga 10441 aaccaagcct atagtcaggc cgagaacgcc atggcacgga agaagccatg ctgcctgtga 10501 gcccctcaga ggacactgag tcaaaaaacc ccacgcgctt ggaggcgcag gatgggaaaa 10561 gaaggtggcg accttcccca cccttcaatc tggggcctga actggagat

Sequences producing significant alignments: Select:AllNone Selected:0 AlignmentsDownloadGenBankGraphicsDistance tree of resultsShow/hide columns of the table presenting sequences producing significant alignments Sequences producing significant alignments: Select for downloading or viewing reports Description Max score Total score Query cover E value Ident Accession Select seq gb|KX842449.1| Zika virus isolate ZIKV/Human/USA/2016/ZF10.UR-010 polyprotein gene, complete cds 18502 18502 100% 0.0 99% KX842449.1 Select seq gb|KX832731.1| Zika virus isolate ZIKV/Human/USA/2016/ZL2.SA-Hu0015 polyprotein gene, complete cds 18493 18493 100% 0.0 99% KX832731.1 Select seq gb|KX838905.1| Zika virus isolate ZIKV/Aedes_aegypti/USA/2016/ZM2-7719 polyprotein gene, complete cds 18489 18489 100% 0.0 99% KX838905.1 Select seq gb|KX838904.1| Zika virus isolate ZIKV/Aedes_aegypti/USA/2016/ZM1-7501 polyprotein gene, complete cds 18484 18484 100% 0.0 99% KX838904.1 Select seq gb|KU853013.1| Zika virus isolate Dominican Republic/2016/PD2, complete genome 18438 18438 100% 0.0 99% KU853013.1 Select seq gb|KU853012.1| Zika virus isolate Dominican Republic/2016/PD1, complete genome 18438 18438 100% 0.0 99% KU853012.1 Select seq gb|KX673530.1| Zika virus isolate PHE_semen_Guadeloupe, complete genome 18417 18417 100% 0.0 99% KX673530.1 Select seq gb|KX838906.1| Zika virus isolate ZIKV/Aedes_aegypti/USA/2016/ZM3-7729 polyprotein gene, complete cds 18408 18408 100% 0.0 99% KX838906.1 Select seq gb|KX447510.1| Zika virus isolate 1_0049_PF polyprotein gene, complete cds 18348 18348 100% 0.0 99% KX447510.1 Select seq gb|KX280026.1| Zika virus isolate Paraiba_01, complete genome 18345 18345 100% 0.0 99% KX280026.1 Select seq gb|KX447512.1| Zika virus isolate 1_0181_PF polyprotein gene, complete cds 18339 18339 100% 0.0 99% KX447512.1 Select seq gb|KX369547.1| Zika virus strain PF13/251013-18, complete genome 18339 18339 100% 0.0 99% KX369547.1 Select seq gb|KU509998.3| Zika virus strain Haiti/1225/2014, complete genome 18339 18339 100% 0.0 99% KU509998.3 Select seq gb|KJ776791.2| Zika virus strain H/PF/2013, complete genome 18336 18336 100% 0.0 99% KJ776791.2 Select seq gb|KX447509.1| Zika virus isolate 1_0087_PF polyprotein gene, complete cds 18336 18336 100% 0.0 99% KX447509.1 Select seq gb|KU991811.1| Zika virus isolate Brazil/2016/INMI1 polyprotein gene, complete cds 18336 18336 100% 0.0 99% KU991811.1 Select seq gb|KU729217.2| Zika virus isolate BeH823339 polyprotein gene, complete cds 18336 18336 100% 0.0 99% KU729217.2 Select seq gb|KX447513.1| Zika virus isolate 1_0134_PF polyprotein gene, complete cds 18330 18330 100% 0.0 99% KX447513.1 Select seq gb|KX811222.1| Zika virus isolate Brazil_2015_MG, complete genome 18327 18327 100% 0.0 99% KX811222.1 Select seq gb|KX197205.1| Zika virus isolate 9, complete genome 18327 18327 100% 0.0 99% KX197205.1 Select seq gb|KX447515.1| Zika virus isolate 1_0030_PF polyprotein gene, complete cds 18327 18327 100% 0.0 99% KX447515.1 Select seq gb|KX447511.1| Zika virus isolate 1_0015_PF polyprotein gene, complete cds 18327 18327 100% 0.0 99% KX447511.1 Select seq gb|KU321639.1| Zika virus strain ZikaSPH2015, complete genome 18327 18327 100% 0.0 99% KU321639.1 Select seq gb|KX879604.1| Zika virus isolate SN089, complete genome 18321 18321 100% 0.0 99% KX879604.1 Select seq gb|KX447514.1| Zika virus isolate 1_0035_PF polyprotein gene, complete cds 18321 18321 100% 0.0 99% KX447514.1 Select seq gb|KX051563.1| Zika virus isolate Haiti/1/2016, complete genome 18321 18321 100% 0.0 99% KX051563.1 Select seq gb|KX447516.1| Zika virus isolate 1_0111_PF polyprotein gene, complete cds 18318 18318 100% 0.0 99% KX447516.1 Select seq gb|KU729218.1| Zika virus isolate BeH828305 polyprotein gene, complete cds 18318 18318 100% 0.0 99% KU729218.1 Select seq gb|KU707826.1| Zika virus isolate SSABR1, complete genome 18318 18318 100% 0.0 99% KU707826.1 Select seq gb|KU527068.1| Zika virus strain Natal RGN, complete genome 18318 18318 100% 0.0 99% KU527068.1 Select seq gb|KU365779.1| Zika virus strain BeH819966 polyprotein gene, complete cds 18318 18318 100% 0.0 99% KU365779.1 Select seq gb|KX879603.1| Zika virus isolate SN062, complete genome 18312 18312 100% 0.0 99% KX879603.1 Select seq gb|KX262887.1| Zika virus isolate 103451, complete genome 18312 18312 100% 0.0 99% KX262887.1 Select seq gb|KX197192.1| Zika virus isolate ZIKV/H.sapiens/Brazil/PE243/2015, complete genome 18312 18312 100% 0.0 99% KX197192.1 Select seq gb|KU926310.1| Zika virus isolate Rio-S1, complete genome 18312 18312 100% 0.0 99% KU926310.1 Select seq gb|KU926309.1| Zika virus isolate Rio-U1, complete genome 18312 18312 100% 0.0 99% KU926309.1 Select seq gb|KU940228.1| Zika virus isolate Bahia07, partial genome 18309 18309 100% 0.0 99% KU940228.1 Select seq gb|KX694534.1| Zika virus strain ZIKV/Homo sapiens/HND/R103451/2015, complete genome 18303 18303 100% 0.0 99% KX694534.1 Select seq gb|KX198135.1| Zika virus strain ZIKV/Homo sapiens/PAN/BEI-259634_V4/2016, complete genome 18303 18303 100% 0.0 99% KX198135.1 Select seq gb|KU501217.1| Zika virus strain 8375 polyprotein gene, complete cds 18303 18303 100% 0.0 99% KU501217.1 Select seq gb|KU365780.1| Zika virus strain BeH815744 polyprotein gene, complete cds 18303 18303 100% 0.0 99% KU365780.1 Select seq gb|KU647676.1| Zika virus strain MRS_OPY_Martinique_PaRi_2015 polyprotein gene, complete cds 18300 18300 100% 0.0 99% KU647676.1 Select seq gb|KU501216.1| Zika virus strain 103344 polyprotein gene, complete cds 18300 18300 100% 0.0 99% KU501216.1 Select seq gb|KU365777.1| Zika virus strain BeH818995 polyprotein gene, complete cds 18300 18300 100% 0.0 99% KU365777.1 Select seq gb|KX447517.1| Zika virus isolate 1_0038_PF polyprotein gene, complete cds 18294 18294 100% 0.0 99% KX447517.1 Select seq gb|KU758877.1| Zika virus isolate 17271 polyprotein gene, complete cds 18294 18294 100% 0.0 99% KU758877.1 Select seq gb|KX247646.1| Zika virus isolate Zika virus/Homo sapiens/COL/UF-1/2016, complete genome 18294 18294 100% 0.0 99% KX247646.1 Select seq gb|KX156776.1| Zika virus strain ZIKV/Homo sapiens/PAN/CDC-259364_V1-V2/2015, complete genome 18294 18294 100% 0.0 99% KX156776.1 Select seq gb|KX520666.1| Zika virus isolate HS-2015-BA-01 polyprotein gene, complete cds 18291 18291 100% 0.0 99% KX520666.1 Select seq gb|KX156774.1| Zika virus strain ZIKV/Homo sapiens/PAN/CDC-259359_V1-V3/2015, complete genome 18291 18291 100% 0.0 99% KX156774.1 Select seq gb|KU497555.1| Zika virus isolate Brazil-ZKV2015, complete genome 18291 18291 99% 0.0 99% KU497555.1 Select seq gb|KU820897.5| Zika virus isolate FLR polyprotein gene, complete cds 18285 18285 100% 0.0 99% KU820897.5 Select seq gb|KX247632.1| Zika virus isolate MEX_I_7 polyprotein gene, complete cds 18285 18285 100% 0.0 99% KX247632.1 Select seq gb|KX156775.1| Zika virus strain ZIKV/Homo sapiens/PAN/CDC-259249_V1-V3/2015, complete genome 18285 18285 100% 0.0 99% KX156775.1 Select seq gb|KX087102.1| Zika virus strain ZIKV/Homo sapiens/COL/FLR/2015, complete genome 18285 18285 100% 0.0 99% KX087102.1 Select seq gb|KU365778.1| Zika virus strain BeH819015 polyprotein gene, complete cds 18285 18285 100% 0.0 99% KU365778.1 Select seq gb|KU312312.1| Zika virus isolate Z1106033 polyprotein gene, complete cds 18285 18285 100% 0.0 99% KU312312.1 Select seq gb|KU922960.1| Zika virus isolate MEX/InDRE/Sm/2016, complete genome 18282 18282 100% 0.0 99% KU922960.1 Select seq gb|KX856011.1| Zika virus strain ZIKV/Aedes sp./MEX_I-44/2016, complete genome 18276 18276 100% 0.0 99% KX856011.1 Select seq gb|KX806557.1| Zika virus isolate TS17-2016, complete genome 18276 18276 100% 0.0 99% KX806557.1 Select seq gb|KX548902.1| Zika virus isolate ZIKV/COL/FCC00093/2015 polyprotein gene, complete cds 18276 18276 100% 0.0 99% KX548902.1 Select seq gb|KX446951.1| Zika virus strain ZIKV/Aedes.sp/MEX/MEX_I-7/2016, complete genome 18276 18276 100% 0.0 99% KX446951.1 Select seq gb|KU937936.1| Zika virus isolate ZIKVNL00013 polyprotein gene, complete cds 18276 18276 100% 0.0 99% KU937936.1 Select seq gb|KU922923.1| Zika virus isolate MEX/InDRE/Lm/2016, complete genome 18276 18276 100% 0.0 99% KU922923.1 Select seq gb|KU501215.1| Zika virus strain PRVABC59, complete genome 18276 18276 100% 0.0 99% KU501215.1 Select seq gb|KX601168.1| Zika virus strain ZIKV/Homo Sapiens/PRI/PRVABC59/2015, complete genome 18273 18273 100% 0.0 99% KX601168.1 Select seq gb|KX446950.1| Zika virus strain ZIKV/Aedes.sp/MEX/MEX_2-81/2016, complete genome 18273 18273 100% 0.0 99% KX446950.1 Select seq gb|KX087101.2| Zika virus strain ZIKV/Homo sapiens/PRI/PRVABC59/2015, complete genome 18273 18273 100% 0.0 99% KX087101.2 Select seq gb|KU870645.1| Zika virus isolate FB-GWUH-2016, complete genome 18273 18273 100% 0.0 99% KU870645.1 Select seq gb|KX702400.1| Zika virus strain Zika virus/Homo sapiens/VEN/UF-1/2016, complete genome 18267 18267 100% 0.0 99% KX702400.1 Select seq gb|KX377337.1| Zika virus strain PRVABC-59, complete genome 18267 18267 100% 0.0 99% KX377337.1 Select seq gb|KX766029.1| Zika virus isolate R116265, complete genome 18258 18258 100% 0.0 99% KX766029.1 Select seq gb|KU820898.1| Zika virus isolate GZ01 polyprotein gene, complete cds 18258 18258 100% 0.0 99% KU820898.1 Select seq gb|KX056898.1| Zika virus isolate Zika virus/GZ02/2016 polyprotein gene, complete cds 18254 18254 100% 0.0 99% KX056898.1 Select seq gb|KU955590.1| Zika virus isolate Z16019 polyprotein gene, complete cds 18254 18254 100% 0.0 99% KU955590.1 Select seq gb|KX766028.1| Zika virus isolate R114916, complete genome 18251 18251 100% 0.0 99% KX766028.1 Select seq gb|KU740184.2| Zika virus isolate GD01 polyprotein gene, complete cds 18249 18249 100% 0.0 99% KU740184.2 Select seq gb|KU761564.1| Zika virus isolate GDZ16001 polyprotein gene, complete cds 18249 18249 100% 0.0 99% KU761564.1 Select seq gb|KX117076.1| Zika virus isolate Zhejiang04, complete genome 18245 18245 100% 0.0 99% KX117076.1 Select seq gb|KX185891.1| Zika virus isolate Zika virus/CN/SZ02/2016 polyprotein gene, complete cds 18236 18236 100% 0.0 99% KX185891.1 Select seq gb|KU963796.1| Zika virus isolate SZ-WIV01 polyprotein gene, complete cds 18236 18236 100% 0.0 99% KU963796.1 Select seq gb|KX253996.1| Zika virus isolate ZKC2/2016, complete genome 18231 18231 100% 0.0 99% KX253996.1 Select seq gb|KU955589.1| Zika virus isolate Z16006 polyprotein gene, complete cds 18231 18231 100% 0.0 99% KU955589.1 Select seq gb|KU820899.2| Zika virus isolate ZJ03, complete genome 18231 18231 100% 0.0 99% KU820899.2 Select seq gb|KX266255.1| Zika virus isolate ZIKV_SMGC-1, complete genome 18227 18227 100% 0.0 99% KX266255.1 Select seq gb|KU866423.2| Zika virus isolate Zika virus/SZ01/2016/China polyprotein gene, complete cds 18227 18227 100% 0.0 99% KU866423.2 Select seq gb|KU940224.1| Zika virus isolate Bahia09, partial genome 18213 18213 99% 0.0 99% KU940224.1 Select seq gb|KU744693.1| Zika virus isolate VE_Ganxian, complete genome 18092 18092 100% 0.0 99% KU744693.1 Select seq gb|KX827309.1| Zika virus isolate ZKA-16-291 polyprotein gene, complete cds 18069 18069 100% 0.0 99% KX827309.1 Select seq gb|KX813683.1| Zika virus isolate ZKA-16-097 polyprotein gene, complete cds 18056 18056 100% 0.0 99% KX813683.1 Select seq gb|KU681081.3| Zika virus isolate Zika virus/H.sapiens-tc/THA/2014/SV0127- 14, complete genome 18002 18002 100% 0.0 99% KU681081.3 Select seq gb|KX694532.1| Zika virus strain ZIKV/Homo sapiens/THA/PLCal_ZV/2013, complete genome 17879 17879 100% 0.0 99% KX694532.1 Select seq gb|KU955593.1| Zika virus isolate Zika virus/H.sapiens-tc/KHM/2010/FSS13025, complete genome 17695 17695 100% 0.0 98% KU955593.1 Select seq gb|JN860885.1| Zika virus isolate FSS13025 polyprotein gene, partial cds 17694 17694 99% 0.0 98% JN860885.1 Select seq gb|KF993678.1| Zika virus strain PLCal_ZV from Canada polyprotein gene, partial cds 17649 17649 98% 0.0 99% KF993678.1 Select seq gb|EU545988.1| Zika virus polyprotein gene, complete cds 17540 17540 100% 0.0 98% EU545988.1 Select seq gb|KU681082.3| Zika virus isolate Zika virus/H.sapiens-tc/PHL/2012/CPC-0740, complete genome 17392 17392 100% 0.0 98% KU681082.3 Select seq gb|KX601167.1| Zika virus strain ZIKV/Aedes sp./MYS/P6-740/1966, complete genome 16365 16365 100% 0.0 95% KX601167.1 Select seq gb|HQ234499.1| Zika virus isolate P6-740 polyprotein gene, partial cds 16357 16357 99% 0.0 95% HQ234499.1 Select seq gb|KX694533.1| Zika virus strain ZIKV/Aedes aegypti/MYS/P6-740/1966, complete genome 16356 16356 100% 0.0 95% KX694533.1

LOCUS KX922704 10609 bp RNA linear VRL 05-OCT-2016 DEFINITION Zika virus isolate ZIKV/Homo_sapiens/USA/2016/FL030U polyprotein gene, complete cds. ACCESSION KX922704 VERSION KX922704.1 GI:1071930512 DBLINK BioProject: PRJNA342539 BioSample: SAMN05853063 KEYWORDS . SOURCE Zika virus ORGANISM Zika virus Viruses; ssRNA viruses; ssRNA positive-strand viruses, no DNA stage; Flaviviridae; Flavivirus. REFERENCE 1 (bases 1 to 10609) AUTHORS Grubaugh,N., Tan,A., Gangavarupu,K., Oliveira,G., Robles-Sikisaka,R., Cone,M., Kopp,E., Hogan,K., Cannons,A., Michael,S., Isern,S. and Andersen,K. TITLE Zika virus sequences from Florida, USA, 2016 JOURNAL Unpublished REFERENCE 2 (bases 1 to 10609) AUTHORS Grubaugh,N., Tan,A., Gangavarupu,K., Oliveira,G., Robles-Sikisaka,R., Cone,M., Kopp,E., Hogan,K., Cannons,A., Michael,S., Isern,S. and Andersen,K. TITLE Direct Submission JOURNAL Submitted (29-SEP-2016) Department of Immunology and Microbial Science, The Scripps Research Institute, 10550 North Torrey Pines Road, IMM-210, La Jolla, CA 92037, USA COMMENT ##Assembly-Data-START## Assembly Method :: NovoAlign v. V3.04 Sequencing Technology :: Illumina ##Assembly-Data-END## FEATURES Location/Qualifiers source 1..10609 /organism="Zika virus" /mol_type="genomic RNA" /isolate="ZIKV/Homo_sapiens/USA/2016/FL030U" /isolation_source="urine" /host="Homo sapiens" /db_xref="taxon:64320" /country="USA: Miami, Florida" /collection_date="31-Jul-2016" CDS 81..10352 /codon_start=1 /product="polyprotein" /protein_id="AOS90221.1" /db_xref="GI:1071930513" /translation="MKNPKKKSGGFRIVNMLKRGVARVSPFGGLKRLPAGLLLGHGPI RMVLAILAFLRFTAIKPSLGLINRWGSVGKKEAMEIIKKFKKDLAAMLRIINARKEKK RRGADTSVGIVGLLLTTAMAAEVTRRGSAYYMYLDRNDAGEAISFPTTLGMNKCYIQI MDLGHMCDATMSYECPMLDEGVEPDDVDCWCNTTSTWVVYGTCHHKKGEARRSRRAVT LPSHSTRKLQTRSQTWLESREYTKHLIRVENWIFRNPGFALAAAAIAWLLGSSTSQKV IYLVMILLIAPAYSIRCIGVSNRDFVEGMSGGTWVDVVLEHGGCVTVMAQDKPTVDIE LVTTTVSNMAEVRSYCYEASISDMASDSRCPTQGEAYLDKQSDTQYVCKRTLVDRGWG NGCGLFGKGSLVTCAKFACSKKMTGKSIQPENLEYRIMLSVHGSQHSGMIVNDTGHET DENRAKVEITPNSPRAEATLGGFGSLGLDCEPRTGLDFSDLYYLTMNNKHWLVHKEWF HDIPLPWHAGADTGTPHWNNKEALVEFKDAHAKRQTVVVLGSQEGAVHTALAGALEAE MDGAKGRLSSGHLKCRLKMDKLRLKGVSYSLCTAAFTFTKIPAETLHGTVTVEVQYAG TDGPCKVPAQMAVDMQTLTPVGRLITANPVITESTENSKMMLELDPPFGDSYIVIGVG EKKITHHWHRSGSTIGKAFEATVRGAKRMAVLGDTAWDFGSVGGALNSLGKGIHQIFG AAFKSLFGGMSWFSQILIGTLLMWLGLNTKNGSISLMCLALGGVLIFLSTAVSADVGC SVDFSKKETRCGTGVFVYNDVEAWRDRYKYHPDSPRRLAAAVKQAWEDGICGISSVSR MENIMWRSVEGELNAILEENGVQLTVVVGSVKNPMWRGPQRLPVPVNELPHGWKAWGK SYFVRAAKTNNSFVVDGDTLKECPLKHRAWNSFLVEDHGFGVFHTSVWLKVREDYSLE CDPAVIGTAVKGKEAVHSDLGYWIESEKNDTWRLKRAHLIEMKTCEWPKSHTLWTDGI EESDLIIPKSLAGPLSHHNTREGYRTQMKGPWHSEELEIRFEECPGTKVHVEETCGTR GPSLRSTTASGRVIEEWCCRECTMPPLSFRAKDGCWYGMEIRPRKEPESNLVRSVVTA GSTDHMDHFSLGVLVILLMVQEGLKKRMTTKIIISTSMAVLVAMILGGFSMSDLAKLA ILMGATFAEMNTGGDVAHLALIAAFKVRPALLVSFIFRANWTPRESMLLALASCLLQT AISALEGDLMVLINGFALAWLAIRAMVVPRTDNITLAILAALTPLARGTLLVAWRAGL ATCGGFMLLSLKGKGSVKKNLPFVMALGLTAVRLVDPINVVGLLLLTRSGKRSWPPSE VLTAVGLICALAGGFAKADIEMAGPMAAVGLLIVSYVVSGKSVDMYIERAGDITWEKD AEVTGNSPRLDVALDESGDFSLVEDDGPPMREIILKVVLMTICGMNPIAIPFAAGAWY VYVKTGKRSGALWDVPAPKEVKKGETTDGVYRVMTRRLLGSTQVGVGVMQEGVFHTMW HVTKGSALRSGEGRLDPYWGDVKQDLVSYCGPWKLDAAWDGHSEVQLLAVPPGERARN IQTLPGIFKTKDGDIGAVALDYPAGTSGSPILDKCGRVIGLYGNGVVIKNGSYVSAIT QGRREEETPVECFEPSMLKKKQLTVLDLHPGAGKTRRVLPEIVREAIKTRLRTVILAP TRVVAAEMEEALRGLPVRYMTTAVNVTHSGTEIVDLMCHATFTSRLLQPIRVPNYNLY IMDEAHFTDPSSIAARGYISTRVEMGEAAAIFMTATPPGTRDAFPDSNSPIMDTEVEV PERAWSSGFDWVTDHSGKTVWFVPSVRNGNEIAACLTKAGKRVIQLSRKTFETEFQKT KHQEWDFVVTTDISEMGANFKADRVIDSRRCLKPVILDGERVILAGPMPVTHASAAQR RGRIGRNPNKPGDEYLYGGGCAETDEDHAHWLEARMLLDNIYLQDGLIASLYRPEADK VAAIEGEFKLRTEQRKTFVELMKRGDLPVWLAYQVASAGITYTDRRWCFDGTTNNTIM EDSVPAEVWTRHGEKRVLKPRWMDARVCSDHAALKSFKEFAAGKRGAAFGVMEALGTL PGHMTERFQEAIDNLAVLMRAETGSRPYKAAAAQLPETLETIMLLGLLGTVSLGIFFV LMRNKGIGKMGFGMVTLGASAWLMWLSEIEPARIACVLIVVFLLLVVLIPEPEKQRSP QDNQMAIIIMVAVGLLGLITANELGWLERTKSDLSHLMGRREEGATIGFSMDIDLRPA SAWAIYAALTTFITPAVQHAVTTSYNNYSLMAMATQAGVLFGMGKGMPFYAWDFGVPL LMIGCYSQLTPLTLIVAIILLVAHYMYLIPGLQAAAARAAQKRTAAGIMKNPVVDGIV VTDIDTMTIDPQVEKKMGQVLLIAVAVSSAILSRTAWGWGEAGALITAATSTLWEGSP NKYWNSSTATSLCNIFRGSYLAGASLIYTVTRNAGLVKRRGGGTGETLGEKWKARLNQ MSALEFYSYKKSGITEVCREEARRALKDGVATGGHAVSRGSAKLRWLVERGYLQPYGK VIDLGCGRGGWSYYAATIRKVQEVKGYTKGGPGHEEPVLVQSYGWNIVRLKSGVDVFH MAAEPCDTLLCDIGESSSSPEVEEARTLRVLSMVGDWLEKRPGAFCIKVLCPYTSTMM ETLERLQRRYGGGLVRVPLSRNSTHEMYWVSGAKSNTIKSVSTTSQLLLGRMDGPRRP VKYEEDVNLGSGTRAVVSCAEAPNMKIIGNRIERIRSEHAETWFFDENHPYRTWAYHG SYEAPTQGSASSLVNGVVRLLSKPWDVVTGVTGIAMTDTTPYGQQRVFKEKVDTRVPD PQEGTRQVMSMVSSWLWKELGKHKRPRVCTKEEFINKVRSNAALGAIFEEEKEWKTAV EAVNDPRFWALVDKEREHHLRGECQSCVYNMMGKREKKQGEFGKAKGSRAIWYMWLGA RFLEFEALGFLNEDHWMGRENSGGGVEGLGLQRLGYVLEEMSRIPGGRMYADDTAGWD TRISRFDLENEALITNQMEKGHRALALAIIKYTYQNKVVKVLRPAEKGKTVMDIISRQ DQRGSGQVVTYALNTFTNLVVQLIRNMEAEEVLEMQDLWLLRRSEKVTNWLQSNGWDR LKRMAVSGDDCVVKPIDDRFAHALRFLNDMGKVRKDTQEWKPSTGWDNWEEVPFCSHH FNKLHLKDGRSIVVPCRHQDELIGRARVSPGAGWSIRETACLAKSYAQMWQLLYFHRR DLRLMANAICSSVPVDWVPTGRTTWSIHGKGEWMTIEDMLVVWNRVWIEENDHMEDKT PVTKWTDIPYLGKREDLWCGSLIGHRPRTTWAENIKNTVNMVRRIIGEEEKYMDYLST QVRYLGEEGSTPGVL" ORIGIN 1 cgacagttcg agtttgaagc gaaagctagc aacagtatca acaggtttta ttttggattt 61 ggaaacgaga gtttctggtc atgaaaaacc caaaaaagaa atccggagga ttccggattg 121 tcaatatgct aaaacgcgga gtagcccgtg tgagcccctt tgggggcttg aagaggctgc 181 cagccggact tctgctgggt catgggccca tcaggatggt cttggcgatt ctagcctttt 241 tgagattcac ggcaatcaag ccatcactgg gtctcatcaa tagatggggt tcagtgggga 301 aaaaagaggc tatggaaata ataaagaagt tcaagaaaga tctggctgcc atgctgagaa 361 taatcaatgc taggaaggag aagaagagac gaggcgcaga tactagtgtc ggaattgttg 421 gcctcctgct gaccacagct atggcagcgg aggtcactag acgtgggagt gcatactaca 481 tgtacttgga cagaaacgat gctggggagg ccatatcttt cccaaccaca ttggggatga 541 ataagtgtta tatacagatc atggatcttg gacacatgtg tgatgccacc atgagctatg 601 aatgccctat gctggatgag ggggtggaac cagatgacgt cgattgttgg tgcaacacga 661 cgtcaacttg ggttgtgtac ggaacctgcc atcacaaaaa aggtgaagca cggagatcta 721 gaagagctgt gacgctcccc tcccattcca ctaggaagct gcaaacgcgg tcgcaaacct 781 ggttggaatc aagagaatac acaaagcact tgattagagt cgaaaattgg atattcagga 841 accctggctt cgcgttagca gcagctgcca tcgcttggct tttgggaagc tcaacgagcc 901 aaaaagttat atacttggtc atgatactgc tgattgcccc ggcatacagc atcaggtgca 961 taggagtcag caatagggac tttgtggaag gtatgtcagg tgggacttgg gttgatgttg 1021 tcttggaaca tggaggctgt gtcaccgtaa tggcacagga caaaccgact gtcgacatag 1081 agctggttac aacaacagtc agcaacatgg cggaggtaag atcctactgc tatgaggcat 1141 caatatcaga catggcttcg gacagccgct gcccaacaca aggtgaagcc taccttgaca 1201 agcaatcaga cactcaatat gtctgcaaaa gaacgttagt ggacagaggc tggggaaatg 1261 gatgtggact ttttggcaaa gggagcctgg tgacatgcgc taagtttgca tgctccaaga 1321 aaatgaccgg gaagagcatc cagccagaga atctggagta ccggataatg ctgtcagttc 1381 atggctccca gcacagtggg atgatcgtta atgacacagg acatgaaact gatgagaata 1441 gagcgaaggt tgagataacg cccaattcac caagagccga agccaccctg gggggttttg 1501 gaagcctagg actggattgt gaaccgagga caggccttga cttttcagat ttgtattact 1561 tgactatgaa taacaagcac tggttggttc acaaggagtg gttccacgac attccattac 1621 cttggcacgc tggggcagac accggaactc cacactggaa caacaaagaa gcactggtag 1681 agttcaagga cgcacatgcc aaaaggcaaa ctgtcgtggt tctagggagt caagaaggag 1741 cagttcacac ggcccttgct ggagctctgg aggctgagat ggatggtgca aagggaaggc 1801 tgtcctctgg ccacttgaaa tgtcgcctga aaatggataa acttagattg aagggcgtgt 1861 catactcctt gtgtaccgca gcgttcacat tcaccaagat cccggctgaa acactgcacg 1921 ggacagtcac agtggaggta cagtacgcag ggacagatgg accttgcaag gttccagctc 1981 agatggcggt ggacatgcaa actctgaccc cagttgggag gttgataacc gccaaccccg 2041 taatcactga aagcactgag aactctaaga tgatgctgga acttgatcca ccatttgggg 2101 actcttacat tgtcatagga gtcggggaga agaagatcac ccaccactgg cacaggagtg 2161 gcagcaccat tggaaaagca tttgaagcca ctgtgagagg tgccaagaga atggcagtct 2221 tgggagatac agcctgggac tttggatcag ttggaggcgc tctcaactca ttgggcaagg 2281 gcatccatca aatttttgga gcagctttca aatcattgtt tggaggaatg tcctggttct 2341 cacaaatcct cattggaacg ttgctgatgt ggttgggtct gaacacaaag aatggatcta 2401 tttccctcat gtgcttggcc ttagggggag tgttgatctt cttatccaca gccgtctctg 2461 ctgatgtggg gtgctcggtg gacttctcaa agaaggagac gagatgcggt acaggggtgt 2521 tcgtctataa cgacgttgaa gcctggaggg acaggtacaa gtaccatcct gactcccccc 2581 gtagattggc agcagcagtc aagcaagcct gggaagatgg tatctgcggg atctcctctg 2641 tttcaagaat ggaaaacatc atgtggagat cagtagaagg ggagctcaat gcaatcctgg 2701 aagagaatgg agttcaactg acggtcgttg tgggatctgt aaaaaacccc atgtggagag 2761 gtccacagag attgcccgtg cctgtgaacg agctgcccca cggctggaag gcttggggga 2821 aatcgtactt cgttagagca gcaaagacaa ataacagctt tgtcgtggat ggtgacacac 2881 tgaaggaatg cccactcaaa catagagcat ggaacagctt tcttgtggag gatcatgggt 2941 tcggggtatt tcacactagt gtctggctca aggttagaga agattattca ttagagtgtg 3001 atccagccgt tattggaaca gctgttaagg gaaaggaggc tgtacacagt gatctaggct 3061 actggattga gagtgagaag aatgacacat ggaggctgaa gagggcccat ctgatcgaga 3121 tgaaaacatg tgaatggcca aagtcccaca cattgtggac agatggaata gaagagagtg 3181 atctgatcat acccaagtct ttagctgggc cactcagcca tcacaatacc agagagggct 3241 acaggaccca aatgaaaggg ccatggcaca gtgaagagct tgaaattcgg tttgaggaat 3301 gcccaggcac taaggtccac gtggaggaaa catgtggaac aagaggacca tctctgagat 3361 caaccactgc aagcggaagg gtgatcgagg aatggtgctg cagggagtgc acaatgcccc 3421 cactgtcgtt ccgggctaaa gatggctgtt ggtatggaat ggagataagg cccaggaaag 3481 aaccagaaag caacttagta aggtcagtgg tgactgcagg atcaactgat cacatggatc 3541 acttctccct tggagtgctt gtgattctgc tcatggtgca ggaagggctg aagaagagaa 3601 tgaccacaaa gatcatcata agcacatcaa tggcagtgct ggtagctatg atcctgggag 3661 gattttcaat gagtgacctg gctaagcttg caattttgat gggtgccacc ttcgcggaaa 3721 tgaacactgg aggagatgta gctcatctgg cgctgatagc ggcattcaaa gtcagaccag 3781 cgttgctggt atctttcatc ttcagagcta attggacacc ccgtgaaagc atgctgctgg 3841 ccttggcctc gtgtcttttg caaactgcga tctccgcctt ggaaggcgac ctgatggttc 3901 tcatcaatgg ttttgctttg gcctggttgg caatacgagc gatggttgtt ccacgcactg 3961 ataacatcac cttggcaatc ctggctgctc tgacaccact ggcccggggc acactgcttg 4021 tggcgtggag agcaggcctt gctacttgcg gggggtttat gctcctctct ctgaagggaa 4081 aaggcagtgt gaagaagaac ttaccatttg tcatggccct gggactaacc gctgtgaggc 4141 tggtcgaccc catcaacgtg gtgggactgc tgttgctcac aaggagtggg aagcggagct 4201 ggccccctag cgaagtactc acagctgttg gcctgatatg cgcattggct ggagggttcg 4261 ccaaggcaga tatagagatg gctgggccca tggccgcggt cggtctgcta attgtcagtt 4321 acgtggtctc aggaaagagt gtggacatgt acattgaaag agcaggtgac atcacatggg 4381 aaaaagatgc ggaagtcact ggaaacagtc cccggctcga tgtggcgcta gatgagagtg 4441 gtgatttctc cctggtggag gatgacggtc cccccatgag agagatcata ctcaaggtgg 4501 tcctgatgac catctgtggc atgaacccaa tagccatacc ctttgcagct ggagcgtggt 4561 acgtatacgt gaagactgga aaaaggagtg gtgctctatg ggatgtgcct gctcccaagg 4621 aagtaaaaaa gggggagacc acagatggag tgtacagagt aatgactcgt agactgctag 4681 gttcaacaca agttggagtg ggagttatgc aagagggggt ctttcacact atgtggcacg 4741 tcacaaaagg atccgcgctg agaagcggtg aagggagact tgatccatac tggggagatg 4801 tcaagcagga tctggtgtca tactgtggtc catggaagct agatgccgcc tgggacgggc 4861 acagcgaggt gcagctcttg gccgtgcccc ccggagagag agcgaggaac atccagactc 4921 tgcccggaat atttaagaca aaggatgggg acattggagc ggttgcgctg gattacccag 4981 caggaacttc aggatcccca atcctagaca agtgtgggag agtgatagga ctttatggca 5041 atggggtcgt gatcaaaaat gggagttatg ttagtgccat cacccaaggg aggagggagg 5101 aagagactcc tgttgagtgc ttcgagcctt cgatgctgaa gaagaagcag ctaactgtct 5161 tagacttgca tcctggagct ggaaaaacca ggagagttct tcctgaaata gtccgtgaag 5221 ctataaaaac aagactccgt actgtgatct tagctccaac cagggttgtc gctgctgaaa 5281 tggaggaagc ccttagaggg cttccagtgc gttatatgac aacagcagtc aatgtcaccc 5341 attctggaac agaaatcgtc gacttaatgt gccatgccac cttcacttca cgtctactac 5401 agccaatcag agtccccaac tataatctgt atattatgga tgaggcccac ttcacagatc 5461 cctcaagtat agcagcaaga ggatacattt caacaagggt tgagatgggc gaggcggctg 5521 ccatcttcat gaccgccacg ccaccaggaa cccgtgacgc atttccggac tccaactcac 5581 caattatgga caccgaagtg gaagtcccag agagagcctg gagctcaggc tttgattggg 5641 tgacggatca ttctggaaaa acagtttggt ttgttccaag cgtgaggaac ggcaatgaga 5701 tcgcagcttg tctgacaaag gctggaaaac gggtcataca gctcagcaga aagacttttg 5761 agacagagtt ccagaaaaca aaacatcaag agtgggactt tgtcgtgaca accgacattt 5821 cagagatggg cgccaacttt aaagctgacc gtgtcataga ttccaggaga tgcctaaagc 5881 cggtcatact tgatggcgag agagtcattc tggctggacc catgcctgtc acacatgcca 5941 gcgctgccca gaggaggggg cgcataggca ggaatcccaa caaacctgga gatgagtatc 6001 tgtatggagg tgggtgcgca gagactgacg aagaccatgc acactggctt gaagcaagaa 6061 tgctccttga caatatttac ctccaagatg gcctcatagc ctcgctctat cgacctgagg 6121 ccgacaaagt agcagccatt gagggagagt tcaagcttag gacggagcaa aggaagacct 6181 ttgtggaact catgaaaaga ggagatcttc ctgtttggct ggcctatcag gttgcatctg 6241 ccggaataac ttacacagat agaagatggt gctttgatgg cacgaccaac aacaccataa 6301 tggaagacag tgtgccggca gaggtgtgga ccagacacgg agagaaaaga gtgctcaaac 6361 cgaggtggat ggacgccaga gtttgttcag atcatgcggc cctgaagtca ttcaaggagt 6421 ttgccgctgg gaaaagagga gcggcttttg gagtgatgga agccctggga acactgccag 6481 gacacatgac agagagattc caggaagcca ttgacaacct cgctgtgctc atgcgggcag 6541 agactggaag caggccttac aaagccgcgg cggcccaatt gccggagacc ctagagacca 6601 ttatgctttt ggggttgctg ggaacagtct cgctgggaat ctttttcgtc ttgatgagga 6661 acaagggcat agggaagatg ggctttggaa tggtgactct tggggccagc gcatggctca 6721 tgtggctctc ggaaattgag ccagccagaa ttgcatgtgt cctcattgtt gtgttcctat 6781 tgctggtggt gctcatacct gagccagaaa agcaaagatc tccccaggac aaccaaatgg 6841 caatcatcat catggtagca gtaggtcttc taggcttgat caccgccaat gaactcggat 6901 ggttggagag aacaaagagt gacctaagcc atctaatggg aaggagagag gagggagcaa 6961 ccataggatt ctcaatggac attgacctgc ggccagcctc agcttgggcc atctatgctg 7021 ccttgacaac tttcattacc ccagccgtcc aacatgcagt gaccacttca tacaacaact 7081 actccttaat ggcgatggcc acgcaagctg gagtgttgtt tggtatgggc aaagggatgc 7141 cattctacgc atgggacttt ggagtcccgc tgctaatgat aggttgctac tcacaattga 7201 cacccctgac cctaatagtg gccatcattt tgctcgtggc gcactacatg tacttgatcc 7261 cagggctgca ggcagcagct gcgcgtgctg cccagaagag aacggcagct ggcatcatga 7321 agaaccctgt tgtggatgga atagtggtga ctgacattga cacaatgaca attgaccccc 7381 aagtggagaa aaagatggga caggtgctac tcatagcagt agccgtctcc agcgccatac 7441 tgtcgcggac cgcctggggg tggggggagg ctggggccct gatcacagcc gcaacttcca 7501 ctttgtggga aggctctccg aacaagtact ggaactcctc tacagccact tcactgtgta 7561 acatttttag gggaagttac ttggctggag cttctctaat ctacacagta acaagaaacg 7621 ctggcttggt caagagacgt gggggtggaa caggagagac cctgggagag aaatggaagg 7681 cccgcttgaa ccagatgtcg gccctggagt tctactccta caaaaagtca ggcatcaccg 7741 aggtgtgcag agaagaggcc cgccgcgccc tcaaggacgg tgtggcaacg ggaggccatg 7801 ctgtgtcccg aggaagtgca aagctgagat ggttggtgga gcggggatac ctgcagccct 7861 atggaaaggt cattgatctt ggatgtggca gagggggctg gagttactac gccgccacca 7921 tccgcaaagt tcaagaagtg aaaggataca caaaaggagg ccctggtcat gaagaacccg 7981 tgttggtgca aagctatggg tggaacatag tccgtctcaa gagtggggtg gacgtctttc 8041 atatggcggc tgagccgtgt gacacgttgc tatgtgacat aggtgagtca tcatctagtc 8101 ctgaagtgga agaagcacgg acgctcagag tcctctccat ggtgggggat tggcttgaaa 8161 aaagaccagg agccttttgt ataaaagtgt tgtgcccata caccagcact atgatggaaa 8221 ccctggagcg actgcagcgt aggtatgggg gaggactggt cagagtgcca ctctcccgca 8281 actctacaca tgagatgtac tgggtctctg gagcgaaaag caacaccata aaaagtgtgt 8341 ccaccacgag ccagctcctc ttggggcgca tggacgggcc taggaggcca gtgaaatatg 8401 aggaggatgt gaatctcggc tctggcacgc gggctgtggt aagctgcgct gaagctccca 8461 acatgaagat cattggtaac cgcattgaaa ggatccgcag tgagcacgcg gaaacgtggt 8521 tctttgacga gaaccaccca tataggacat gggcttacca tggaagctat gaggccccca 8581 cacaagggtc agcatcctct ctagtaaacg gggttgtcag gctcctgtca aaaccctggg 8641 atgtggtgac tggagtcaca ggaatagcca tgaccgacac cacaccgtat ggtcagcaaa 8701 gagttttcaa ggaaaaagtg gacactaggg tgccagaccc ccaagaaggc actcgtcagg 8761 ttatgagcat ggtctcttcc tggttgtgga aagagctagg caaacacaaa cggccacgag 8821 tctgtaccaa agaagagttc atcaacaagg ttcgtagcaa tgcagcatta ggggcaatat 8881 ttgaagagga aaaagagtgg aagactgcag tggaagctgt gaacgatcca aggttctggg 8941 ctctagtgga caaggaaaga gagcaccacc tgagaggaga gtgccagagt tgtgtgtaca 9001 acatgatggg aaaaagagaa aagaaacaag gggaatttgg aaaggccaag ggcagccgcg 9061 ccatctggta tatgtggcta ggggctagat ttctagagtt cgaagccctt ggattcttga 9121 acgaggatca ctggatgggg agagagaact caggaggtgg tgttgaaggg ctgggattac 9181 aaagactcgg atatgtccta gaagagatga gtcgcatacc aggaggaagg atgtatgcag 9241 atgacactgc tggctgggat acccgcatca gcaggtttga tctagagaat gaagctctaa 9301 tcaccaacca aatggagaaa gggcacaggg ccttggcatt ggccataatc aagtacacat 9361 accaaaacaa agtggtaaag gtccttagac cagctgaaaa agggaaaaca gttatggaca 9421 ttatttcgag acaagaccaa agggggagcg gacaagttgt cacttacgct cttaacacat 9481 ttaccaacct agtggtgcaa ctcattcgga atatggaggc tgaggaagtt ctagagatgc 9541 aagacttgtg gctgctgcgg aggtcagaga aagtgaccaa ctggttgcag agcaacggat 9601 gggataggct caaacgaatg gcagtcagtg gagatgattg cgttgtgaag ccaattgatg 9661 ataggtttgc acatgccctc aggttcttga atgatatggg aaaagttagg aaggacacac 9721 aagagtggaa accctcaact ggatgggaca actgggaaga agttccgttt tgctcccacc 9781 acttcaacaa gctccatctc aaggatggga ggtccattgt ggttccctgc cgccaccaag 9841 atgaactgat tggccgggcc cgcgtctctc caggggcggg atggagcatc cgggagactg 9901 cttgcctagc aaaatcatat gcgcaaatgt ggcagctcct ttatttccac agaagggacc 9961 tccgactgat ggccaatgcc atttgttcat ctgtgccagt tgactgggtt ccaactggga 10021 gaactacctg gtcaatccat ggaaagggag aatggatgac cattgaagac atgcttgtgg 10081 tgtggaacag agtgtggatt gaggagaacg accacatgga agacaagacc ccagttacga 10141 aatggacaga cattccctat ttgggaaaaa gggaagactt gtggtgtgga tctctcatag 10201 ggcacagacc gcgcaccacc tgggctgaga acattaaaaa cacagtcaac atggtgcgca 10261 ggatcatagg tgaggaagaa aagtacatgg actacctatc cacccaagtc cgctacttgg 10321 gtgaagaagg gtctacacct ggagtgctgt aagcaccaat cttaatgttg tcaggcctgc 10381 tagtcagcca cagcttgggg aaagctgtgc agcctgtgac ccccccagga gaagctggga 10441 aaccaagcct atagtcaggc cgagaacgcc atggcacgga agaagccatg ctgcctgtga 10501 gcccctcaga ggacactgag tcaaaaaacc ccacgcgctt ggaggcgcag gatgggaaaa 10561 gaaggtggcg accttcccca cccttcaatc tggggcctga actggagat

Sequences producing significant alignments: Select:AllNone Selected:0 AlignmentsDownloadGenBankGraphicsDistance tree of resultsShow/hide columns of the table presenting sequences producing significant alignments Sequences producing significant alignments: Select for downloading or viewing reports Description Max score Total score Query cover E value Ident Accession Select seq gb|KX842449.1| Zika virus isolate ZIKV/Human/USA/2016/ZF10.UR-010 polyprotein gene, complete cds 18507 18507 100% 0.0 99% KX842449.1 Select seq gb|KX838905.1| Zika virus isolate ZIKV/Aedes_aegypti/USA/2016/ZM2-7719 polyprotein gene, complete cds 18502 18502 100% 0.0 99% KX838905.1 Select seq gb|KX832731.1| Zika virus isolate ZIKV/Human/USA/2016/ZL2.SA-Hu0015 polyprotein gene, complete cds 18498 18498 100% 0.0 99% KX832731.1 Select seq gb|KX838904.1| Zika virus isolate ZIKV/Aedes_aegypti/USA/2016/ZM1-7501 polyprotein gene, complete cds 18489 18489 100% 0.0 99% KX838904.1 Select seq gb|KU853013.1| Zika virus isolate Dominican Republic/2016/PD2, complete genome 18444 18444 100% 0.0 99% KU853013.1 Select seq gb|KU853012.1| Zika virus isolate Dominican Republic/2016/PD1, complete genome 18442 18442 100% 0.0 99% KU853012.1 Select seq gb|KX673530.1| Zika virus isolate PHE_semen_Guadeloupe, complete genome 18420 18420 100% 0.0 99% KX673530.1 Select seq gb|KX838906.1| Zika virus isolate ZIKV/Aedes_aegypti/USA/2016/ZM3-7729 polyprotein gene, complete cds 18411 18411 100% 0.0 99% KX838906.1 Select seq gb|KX447510.1| Zika virus isolate 1_0049_PF polyprotein gene, complete cds 18354 18354 100% 0.0 99% KX447510.1 Select seq gb|KX280026.1| Zika virus isolate Paraiba_01, complete genome 18348 18348 100% 0.0 99% KX280026.1 Select seq gb|KX447512.1| Zika virus isolate 1_0181_PF polyprotein gene, complete cds 18345 18345 100% 0.0 99% KX447512.1 Select seq gb|KX369547.1| Zika virus strain PF13/251013-18, complete genome 18345 18345 100% 0.0 99% KX369547.1 Select seq gb|KU509998.3| Zika virus strain Haiti/1225/2014, complete genome 18345 18345 100% 0.0 99% KU509998.3 Select seq gb|KJ776791.2| Zika virus strain H/PF/2013, complete genome 18339 18339 100% 0.0 99% KJ776791.2 Select seq gb|KX447509.1| Zika virus isolate 1_0087_PF polyprotein gene, complete cds 18339 18339 100% 0.0 99% KX447509.1 Select seq gb|KU991811.1| Zika virus isolate Brazil/2016/INMI1 polyprotein gene, complete cds 18339 18339 100% 0.0 99% KU991811.1 Select seq gb|KU729217.2| Zika virus isolate BeH823339 polyprotein gene, complete cds 18339 18339 100% 0.0 99% KU729217.2 Select seq gb|KX447513.1| Zika virus isolate 1_0134_PF polyprotein gene, complete cds 18336 18336 100% 0.0 99% KX447513.1 Select seq gb|KX811222.1| Zika virus isolate Brazil_2015_MG, complete genome 18330 18330 100% 0.0 99% KX811222.1 Select seq gb|KX197205.1| Zika virus isolate 9, complete genome 18330 18330 100% 0.0 99% KX197205.1 Select seq gb|KX447515.1| Zika virus isolate 1_0030_PF polyprotein gene, complete cds 18330 18330 100% 0.0 99% KX447515.1 Select seq gb|KX447511.1| Zika virus isolate 1_0015_PF polyprotein gene, complete cds 18330 18330 100% 0.0 99% KX447511.1 Select seq gb|KU321639.1| Zika virus strain ZikaSPH2015, complete genome 18330 18330 100% 0.0 99% KU321639.1 Select seq gb|KX879604.1| Zika virus isolate SN089, complete genome 18327 18327 100% 0.0 99% KX879604.1 Select seq gb|KX447514.1| Zika virus isolate 1_0035_PF polyprotein gene, complete cds 18327 18327 100% 0.0 99% KX447514.1 Select seq gb|KX051563.1| Zika virus isolate Haiti/1/2016, complete genome 18327 18327 100% 0.0 99% KX051563.1 Select seq gb|KX447516.1| Zika virus isolate 1_0111_PF polyprotein gene, complete cds 18321 18321 100% 0.0 99% KX447516.1 Select seq gb|KU729218.1| Zika virus isolate BeH828305 polyprotein gene, complete cds 18321 18321 100% 0.0 99% KU729218.1 Select seq gb|KU707826.1| Zika virus isolate SSABR1, complete genome 18321 18321 100% 0.0 99% KU707826.1 Select seq gb|KU527068.1| Zika virus strain Natal RGN, complete genome 18321 18321 100% 0.0 99% KU527068.1 Select seq gb|KU365779.1| Zika virus strain BeH819966 polyprotein gene, complete cds 18321 18321 100% 0.0 99% KU365779.1 Select seq gb|KX879603.1| Zika virus isolate SN062, complete genome 18318 18318 100% 0.0 99% KX879603.1 Select seq gb|KX262887.1| Zika virus isolate 103451, complete genome 18318 18318 100% 0.0 99% KX262887.1 Select seq gb|KX197192.1| Zika virus isolate ZIKV/H.sapiens/Brazil/PE243/2015, complete genome 18318 18318 100% 0.0 99% KX197192.1 Select seq gb|KU926310.1| Zika virus isolate Rio-S1, complete genome 18318 18318 100% 0.0 99% KU926310.1 Select seq gb|KU926309.1| Zika virus isolate Rio-U1, complete genome 18318 18318 100% 0.0 99% KU926309.1 Select seq gb|KU940228.1| Zika virus isolate Bahia07, partial genome 18312 18312 100% 0.0 99% KU940228.1 Select seq gb|KX694534.1| Zika virus strain ZIKV/Homo sapiens/HND/R103451/2015, complete genome 18309 18309 100% 0.0 99% KX694534.1 Select seq gb|KX198135.1| Zika virus strain ZIKV/Homo sapiens/PAN/BEI-259634_V4/2016, complete genome 18309 18309 100% 0.0 99% KX198135.1 Select seq gb|KU501217.1| Zika virus strain 8375 polyprotein gene, complete cds 18309 18309 100% 0.0 99% KU501217.1 Select seq gb|KU365780.1| Zika virus strain BeH815744 polyprotein gene, complete cds 18309 18309 100% 0.0 99% KU365780.1 Select seq gb|KU647676.1| Zika virus strain MRS_OPY_Martinique_PaRi_2015 polyprotein gene, complete cds 18303 18303 100% 0.0 99% KU647676.1 Select seq gb|KU501216.1| Zika virus strain 103344 polyprotein gene, complete cds 18303 18303 100% 0.0 99% KU501216.1 Select seq gb|KU365777.1| Zika virus strain BeH818995 polyprotein gene, complete cds 18303 18303 100% 0.0 99% KU365777.1 Select seq gb|KX447517.1| Zika virus isolate 1_0038_PF polyprotein gene, complete cds 18300 18300 100% 0.0 99% KX447517.1 Select seq gb|KU758877.1| Zika virus isolate 17271 polyprotein gene, complete cds 18300 18300 100% 0.0 99% KU758877.1 Select seq gb|KX247646.1| Zika virus isolate Zika virus/Homo sapiens/COL/UF-1/2016, complete genome 18300 18300 100% 0.0 99% KX247646.1 Select seq gb|KX156776.1| Zika virus strain ZIKV/Homo sapiens/PAN/CDC-259364_V1-V2/2015, complete genome 18300 18300 100% 0.0 99% KX156776.1 Select seq gb|KU497555.1| Zika virus isolate Brazil-ZKV2015, complete genome 18296 18296 99% 0.0 99% KU497555.1 Select seq gb|KX520666.1| Zika virus isolate HS-2015-BA-01 polyprotein gene, complete cds 18294 18294 100% 0.0 99% KX520666.1 Select seq gb|KX156774.1| Zika virus strain ZIKV/Homo sapiens/PAN/CDC-259359_V1-V3/2015, complete genome 18294 18294 100% 0.0 99% KX156774.1 Select seq gb|KU820897.5| Zika virus isolate FLR polyprotein gene, complete cds 18291 18291 100% 0.0 99% KU820897.5 Select seq gb|KX247632.1| Zika virus isolate MEX_I_7 polyprotein gene, complete cds 18291 18291 100% 0.0 99% KX247632.1 Select seq gb|KX156775.1| Zika virus strain ZIKV/Homo sapiens/PAN/CDC-259249_V1-V3/2015, complete genome 18291 18291 100% 0.0 99% KX156775.1 Select seq gb|KX087102.1| Zika virus strain ZIKV/Homo sapiens/COL/FLR/2015, complete genome 18291 18291 100% 0.0 99% KX087102.1 Select seq gb|KU365778.1| Zika virus strain BeH819015 polyprotein gene, complete cds 18291 18291 100% 0.0 99% KU365778.1 Select seq gb|KU312312.1| Zika virus isolate Z1106033 polyprotein gene, complete cds 18291 18291 100% 0.0 99% KU312312.1 Select seq gb|KU922960.1| Zika virus isolate MEX/InDRE/Sm/2016, complete genome 18285 18285 100% 0.0 99% KU922960.1 Select seq gb|KX856011.1| Zika virus strain ZIKV/Aedes sp./MEX_I-44/2016, complete genome 18282 18282 100% 0.0 99% KX856011.1 Select seq gb|KX806557.1| Zika virus isolate TS17-2016, complete genome 18282 18282 100% 0.0 99% KX806557.1 Select seq gb|KX548902.1| Zika virus isolate ZIKV/COL/FCC00093/2015 polyprotein gene, complete cds 18282 18282 100% 0.0 99% KX548902.1 Select seq gb|KX446951.1| Zika virus strain ZIKV/Aedes.sp/MEX/MEX_I-7/2016, complete genome 18282 18282 100% 0.0 99% KX446951.1 Select seq gb|KU937936.1| Zika virus isolate ZIKVNL00013 polyprotein gene, complete cds 18282 18282 100% 0.0 99% KU937936.1 Select seq gb|KU922923.1| Zika virus isolate MEX/InDRE/Lm/2016, complete genome 18282 18282 100% 0.0 99% KU922923.1 Select seq gb|KU501215.1| Zika virus strain PRVABC59, complete genome 18282 18282 100% 0.0 99% KU501215.1 Select seq gb|KX601168.1| Zika virus strain ZIKV/Homo Sapiens/PRI/PRVABC59/2015, complete genome 18276 18276 100% 0.0 99% KX601168.1 Select seq gb|KX446950.1| Zika virus strain ZIKV/Aedes.sp/MEX/MEX_2-81/2016, complete genome 18276 18276 100% 0.0 99% KX446950.1 Select seq gb|KX087101.2| Zika virus strain ZIKV/Homo sapiens/PRI/PRVABC59/2015, complete genome 18276 18276 100% 0.0 99% KX087101.2 Select seq gb|KU870645.1| Zika virus isolate FB-GWUH-2016, complete genome 18276 18276 100% 0.0 99% KU870645.1 Select seq gb|KX702400.1| Zika virus strain Zika virus/Homo sapiens/VEN/UF-1/2016, complete genome 18273 18273 100% 0.0 99% KX702400.1 Select seq gb|KX377337.1| Zika virus strain PRVABC-59, complete genome 18273 18273 100% 0.0 99% KX377337.1 Select seq gb|KX766029.1| Zika virus isolate R116265, complete genome 18264 18264 100% 0.0 99% KX766029.1 Select seq gb|KU820898.1| Zika virus isolate GZ01 polyprotein gene, complete cds 18264 18264 100% 0.0 99% KU820898.1 Select seq gb|KX056898.1| Zika virus isolate Zika virus/GZ02/2016 polyprotein gene, complete cds 18258 18258 100% 0.0 99% KX056898.1 Select seq gb|KU955590.1| Zika virus isolate Z16019 polyprotein gene, complete cds 18258 18258 100% 0.0 99% KU955590.1 Select seq gb|KX766028.1| Zika virus isolate R114916, complete genome 18256 18256 100% 0.0 99% KX766028.1 Select seq gb|KU740184.2| Zika virus isolate GD01 polyprotein gene, complete cds 18254 18254 100% 0.0 99% KU740184.2 Select seq gb|KU761564.1| Zika virus isolate GDZ16001 polyprotein gene, complete cds 18254 18254 100% 0.0 99% KU761564.1 Select seq gb|KX117076.1| Zika virus isolate Zhejiang04, complete genome 18249 18249 100% 0.0 99% KX117076.1 Select seq gb|KX185891.1| Zika virus isolate Zika virus/CN/SZ02/2016 polyprotein gene, complete cds 18240 18240 100% 0.0 99% KX185891.1 Select seq gb|KU963796.1| Zika virus isolate SZ-WIV01 polyprotein gene, complete cds 18240 18240 100% 0.0 99% KU963796.1 Select seq gb|KX253996.1| Zika virus isolate ZKC2/2016, complete genome 18236 18236 100% 0.0 99% KX253996.1 Select seq gb|KU955589.1| Zika virus isolate Z16006 polyprotein gene, complete cds 18236 18236 100% 0.0 99% KU955589.1 Select seq gb|KU820899.2| Zika virus isolate ZJ03, complete genome 18236 18236 100% 0.0 99% KU820899.2 Select seq gb|KX266255.1| Zika virus isolate ZIKV_SMGC-1, complete genome 18233 18233 100% 0.0 99% KX266255.1 Select seq gb|KU866423.2| Zika virus isolate Zika virus/SZ01/2016/China polyprotein gene, complete cds 18231 18231 100% 0.0 99% KU866423.2 Select seq gb|KU940224.1| Zika virus isolate Bahia09, partial genome 18218 18218 99% 0.0 99% KU940224.1 Select seq gb|KU744693.1| Zika virus isolate VE_Ganxian, complete genome 18096 18096 100% 0.0 99% KU744693.1 Select seq gb|KX827309.1| Zika virus isolate ZKA-16-291 polyprotein gene, complete cds 18074 18074 100% 0.0 99% KX827309.1 Select seq gb|KX813683.1| Zika virus isolate ZKA-16-097 polyprotein gene, complete cds 18060 18060 100% 0.0 99% KX813683.1 Select seq gb|KU681081.3| Zika virus isolate Zika virus/H.sapiens-tc/THA/2014/SV0127- 14, complete genome 18006 18006 100% 0.0 99% KU681081.3 Select seq gb|KX694532.1| Zika virus strain ZIKV/Homo sapiens/THA/PLCal_ZV/2013, complete genome 17885 17885 100% 0.0 99% KX694532.1 Select seq gb|KU955593.1| Zika virus isolate Zika virus/H.sapiens-tc/KHM/2010/FSS13025, complete genome 17708 17708 100% 0.0 98% KU955593.1 Select seq gb|JN860885.1| Zika virus isolate FSS13025 polyprotein gene, partial cds 17708 17708 99% 0.0 98% JN860885.1 Select seq gb|KF993678.1| Zika virus strain PLCal_ZV from Canada polyprotein gene, partial cds 17652 17652 98% 0.0 99% KF993678.1 Select seq gb|EU545988.1| Zika virus polyprotein gene, complete cds 17544 17544 100% 0.0 98% EU545988.1 Select seq gb|KU681082.3| Zika virus isolate Zika virus/H.sapiens-tc/PHL/2012/CPC-0740, complete genome 17398 17398 100% 0.0 98% KU681082.3 Select seq gb|KX601167.1| Zika virus strain ZIKV/Aedes sp./MYS/P6-740/1966, complete genome 16370 16370 100% 0.0 95% KX601167.1 Select seq gb|KX694533.1| Zika virus strain ZIKV/Aedes aegypti/MYS/P6-740/1966, complete genome 16361 16361 100% 0.0 95% KX694533.1 Select seq gb|HQ234499.1| Zika virus isolate P6-740 polyprotein gene, partial cds 16361 16361 99% 0.0 95% HQ234499.1

LOCUS KX922703 10365 bp RNA linear VRL 05-OCT-2016 DEFINITION Zika virus isolate ZIKV/Homo_sapiens/USA/2016/FL021U polyprotein gene, complete cds. ACCESSION KX922703 VERSION KX922703.1 GI:1071930510 DBLINK BioProject: PRJNA342539 BioSample: SAMN05853061 KEYWORDS . SOURCE Zika virus ORGANISM Zika virus Viruses; ssRNA viruses; ssRNA positive-strand viruses, no DNA stage; Flaviviridae; Flavivirus. REFERENCE 1 (bases 1 to 10365) AUTHORS Grubaugh,N., Tan,A., Gangavarupu,K., Oliveira,G., Robles-Sikisaka,R., Cone,M., Kopp,E., Hogan,K., Cannons,A., Michael,S., Isern,S. and Andersen,K. TITLE Zika virus sequences from Florida, USA, 2016 JOURNAL Unpublished REFERENCE 2 (bases 1 to 10365) AUTHORS Grubaugh,N., Tan,A., Gangavarupu,K., Oliveira,G., Robles-Sikisaka,R., Cone,M., Kopp,E., Hogan,K., Cannons,A., Michael,S., Isern,S. and Andersen,K. TITLE Direct Submission JOURNAL Submitted (29-SEP-2016) Department of Immunology and Microbial Science, The Scripps Research Institute, 10550 North Torrey Pines Road, IMM-210, La Jolla, CA 92037, USA COMMENT ##Assembly-Data-START## Assembly Method :: NovoAlign v. V3.04 Sequencing Technology :: Illumina ##Assembly-Data-END## FEATURES Location/Qualifiers source 1..10365 /organism="Zika virus" /mol_type="genomic RNA" /isolate="ZIKV/Homo_sapiens/USA/2016/FL021U" /isolation_source="urine" /host="Homo sapiens" /db_xref="taxon:64320" /country="USA: Miami, Florida" /collection_date="09-Jul-2016" CDS 82..10353 /codon_start=1 /product="polyprotein" /protein_id="AOS90220.1" /db_xref="GI:1071930511" /translation="MKNPKKKSGGFRIVNMLKRGVARVSPFGGLKRLPAGLLLGHGPI RMVLAILAFLRFTAIKPSLGLINRWGSVGKKEAMEIIKKFKKDLAAMLRIINARKEKK RRGADTSVGIVGLLLTTAMAAEVTRRGSAYYMYLDRNDAGEAISFPTTLGMNKCYIQI MDLGHMCDATMSYECPMLDEGVEPDDVDCWCNTTSTWVVYGTCHHKKGEARRSRRAVT LPSHSTRKLQTRSQTWLESREYTKHLIRVENWIFRNPGFALAAAAIAWLLGSSTSQKV IYLVMILLIAPAYSIRCIGVSNRDFVEGMSGGTWVDVVLEHGGCVTVMAQDKPTVDIE LVTTTVSNMAEVRSYCYEASISDMASDSRCPTQGEAYLDKQSDTQYVCKRTLVDRGWG NGCGLFGKGSLVTCAKFACSKKMTGKSIQPENLEYRIMLSVHGSQHSGMIVNDTGHET DENRAKVEITPNSPRAEATLGGFGSLGLDCEPRTGLDFSDLYYLTMNNKHWLVHKEWF HDIPLPWHAGADTGTPHWNNKEALVEFKDAHAKRQTVVVLGSQEGAVHTALAGALEAE MDGAKGRLSSGHLKCRLKMDKLRLKGVSYSLCTAAFTFTKIPAETLHGTVTVEVQYAG TDGPCKVPAQMAVDMQTLTPVGRLITANPVITESTENSKMMLELDPPFGDSYIVIGVG EKKITHHWHRSGSTIGKAFEATVRGAKRMAVLGDTAWDFGSVGGALNSLGKGIHQIFG AAFKSLFGGMSWFSQILIGTLLMWLGLNTKNGSISLMCLALGGVLIFLSTAVSADVGC SVDFSKKETRCGTGVFVYNDVEAWRDRYKYHPDSPRRLAAAVKQAWEDGICGISSVSR MENIMWRSVEGELNAILEENGVQLTVVVGSVKNPMWRGPQRLPVPVNELPHGWKAWGK SYFVRAAKTNNSFVVDGDTLKECPLKHRAWNSFLVEDHGFGVFHTSVWLKVREDYSLE CDPAVIGTAVKGKEAVHSDLGYWIESEKNDTWRLKRAHLIEMKTCEWPKSHTLWTDGI EESDLIIPKSLAGPLSHHNTREGYRTQMKGPWHSEELEIRFEECPGTKVHVEETCGTR GPSLRSTTASGRVIEEWCCRECTMPPLSFRAKDGCWYGMEIRPRKEPESNLVRSVVTA GSTDHMDHFSLGVLVILLMVQEGLKKRMTTKIIISTSMAVLVAMILGGFSMGDLAKLA ILMGATFAEMNTGGDVAHLALIAAFKVRPALLVSFIFRANWTPRESMLLALASCLLQT AISALEGDLMVLINGFALAWLAIRAMVVPRTDNITLAILAALTPLARGTLLVAWRAGL ATCGGFMLLSLKGKGSVKKNLPFVMALGLTAVRLVDPINVVGLLLLTRSGKRSWPPSE VLTAVGLICALAGGFAKADIEMAGPMAAVGLLIVSYVVSGKSVDMYIERAGDITWEKD AEVTGNSPRLDVALDESGDFSLVEDDGPPMREIILKVVLMTICGMNPIAIPFAAGAWY VYVKTGKRSGALWDVPAPKEVKKGETTDGVYRVMTRRLLGSTQVGVGVMQEGVFHTMW HVTKGSALRSGEGRLDPYWGDVKQDLVSYCGPWKLDAAWDGHSEVQLLAVPPGERARN IQTLPGIFKTKDGDIGAVALDYPAGTSGSPILDKCGRVIGLYGNGVVIKNGSYVSAIT QGRREEETPVECFEPSMLKKKQLTVLDLHPGAGKTRRVLPEIVREAIKTRLRTVILAP TRVVAAEMEEALRGLPVRYMTTAVNVTHSGTEIVDLMCHATFTSRLLQPIRVPNYNLY IMDEAHFTDPSSIAARGYISTRVEMGEAAAIFMTATPPGTRDAFPDSNSPIMDTEVEV PERAWSSGFDWVTDHSGKTVWFVPSVRNGNEIAACLTKAGKRVIQLSRKTFETEFQKT KHQEWDFVVTTDISEMGANFKADRVIDSRRCLKPVILDGERVILAGPMPVTHASAAQR RGRIGRNPNKPGDEYLYGGGCAETDEDHAHWLEARMLLDNIYLQDGLIASLYRPEADK VAAIEGEFKLRTEQRKTFVELMKRGDLPVWLAYQVASAGITYTDRRWCFDGTTNNTIM EDSVPAEVWTRHGEKRVLKPRWMDARVCSDHAALKSFKEFAAGKRGAAFGVMEALGTL PGHMTERFQEAIDNLAVLMRAETGSRPYKAAAAQLPETLETIMLLGLLGTVSLGIFFV LMRNKGIGKMGFGMVTLGASAWLMWLSEIEPARIACVLIVVFLLLVVLIPEPEKQRSP QDNQMAIIIMVAVGLLGLITANELGWLERTKSDLSHLMGRREEGATIGFSMDIDLRPA SAWAIYAALTTFITPAVQHAVTTSYNNYSLMAMATQAGVLFGMGKGMPFYAWDFGVPL LMIGCYSQLTPLTLIVAIILLVAHYMYLIPGLQAAAARAAQKRTAAGIMKNPVVDGIV VTDIDTMTIDPQVEKKMGQVLLIAVAVSSAILSRTAWGWGEAGALITAATSTLWEGSP NKYWNSSTATSLCNIFRGSYLAGASLIYTVTRNAGLVKRRGGGTGETLGEKWKARLNQ MSALEFYSYKKSGITEVCREEARRALKDGVATGGHAVSRGSAKLRWLVERGYLQPYGK VIDLGCGRGGWSYYAATIRKVQEVKGYTKGGPGHEEPVLVQSYGWNIVRLKSGVDVFH MAAEPCDTLLCDIGESSSSPEVEEARTLRVLSMVGDWLEKRPGAFCIKVLCPYTSTMM ETLERLQRRYGGGLVRVPLSRNSTHEMYWVSGAKSNTIKSVSTTSQLLLGRMDGPRRP VKYEEDVNLGSGTRAVVSCAEAPNMKIIGNRIERIRSEHAETWFFDENHPYRTWAYHG SYEAPTQGSASSLVNGVVRLLSKPWDVVTGVTGIAMTDTTPYGQQRVFKEKVDTRVPD PQEGTRQVMSMVSSWLWKELGKHKRPRVCTKEEFINKVRSNAALGAIFEEEKEWKTAV EAVNDPRFWALVDKEREHHLRGECQSCVYNMMGKREKKQGEFGKAKGSRAIWYMWLGA RFLEFEALGFLNEDHWMGRENSGGGVEGLGLQRLGYVLEEMSRIPGGRMYADDTAGWD TRISRFDLENEALITNQMEKGHRALALAIIKYTYQNKVVKVLRPAEKGKTVMDIISRQ DQRGSGQVVTYALNTFTNLVVQLIRNMEAEEVLEMQDLWLLRRSEKVTNWLQSNGWDR LKRMAVSGDDCVVKPIDDRFAHALRFLNDMGKVRKDTQEWKPSTGWDNWEEVPFCSHH FNKLHLKDGRSIVVPCRHQDELIGRARVSPGAGWSIRETACLAKSYAQMWQLLYFHRR DLRLMANAICSSVPVDWVPTGRTTWSIHGKGEWMTIEDMLVVWNRVWIEENDHMEDKT PVTKWTDIPYLGKREDLWCGSLIGHRPRTTWAENIKNTVNMVRRIIGEEEKYMDYLST QVRYLGEEGSTPGVL" ORIGIN 1 gcgacagttc gagtttgaag cgaaagctag caacagtatc aacaggtttt attttggatt 61 tggaaacgag agtttctggt catgaaaaac ccaaaaaaga aatccggagg attccggatt 121 gtcaatatgc taaaacgcgg agtagcccgt gtgagcccct ttgggggctt gaagaggctg 181 ccagccggac ttctgctggg tcatgggccc atcaggatgg tcttggcgat tctagccttt 241 ttgagattca cggcaatcaa gccatcactg ggtctcatca atagatgggg ttcagtgggg 301 aaaaaagagg ctatggaaat aataaagaag ttcaagaaag atctggctgc catgctgaga 361 ataatcaatg ctaggaagga gaagaagaga cgaggcgcag atactagtgt cggaattgtt 421 ggcctcctgc tgaccacagc tatggcagcg gaggtcacta gacgtgggag tgcatactac 481 atgtacttgg acagaaacga tgctggggag gccatatctt tcccaaccac attggggatg 541 aataagtgtt atatacagat catggatctt ggacacatgt gtgatgccac catgagctat 601 gaatgcccta tgctggatga gggggtggaa ccagatgacg tcgattgttg gtgcaacacg 661 acgtcaactt gggttgtgta cggaacctgc catcacaaaa aaggtgaagc acggagatct 721 agaagagctg tgacgctccc ctcccattcc actaggaagc tgcaaacgcg gtcgcaaacc 781 tggttggaat caagagaata cacaaagcac ttgattagag tcgaaaattg gatattcagg 841 aaccctggct tcgcgttagc agcagctgcc atcgcttggc ttttgggaag ctcaacgagc 901 caaaaagtta tatacttggt catgatactg ctgattgccc cggcatacag catcaggtgc 961 ataggagtca gcaataggga ctttgtggaa ggtatgtcag gtgggacttg ggttgatgtt 1021 gtcttggaac atggaggctg tgtcaccgta atggcacagg acaaaccgac tgtcgacata 1081 gagctggtta caacaacagt cagcaacatg gcggaggtaa gatcctactg ctatgaggca 1141 tcaatatcag acatggcttc ggacagccgc tgcccaacac aaggtgaagc ctaccttgac 1201 aagcaatcag acactcaata tgtctgcaaa agaacgttag tggacagagg ctggggaaat 1261 ggatgtggac tttttggcaa agggagcctg gtgacatgcg ctaagtttgc atgctccaag 1321 aaaatgaccg ggaagagcat ccagccagag aatctggagt accggataat gctgtcagtt 1381 catggctccc agcacagtgg gatgatcgtt aatgacacag gacatgaaac tgatgagaat 1441 agagcgaagg ttgagataac gcccaattca ccaagagccg aagccaccct ggggggtttt 1501 ggaagcctag gactggattg tgaaccgagg acaggccttg acttttcaga tttgtattac 1561 ttgactatga ataacaagca ctggttggtt cacaaggagt ggttccacga cattccatta 1621 ccttggcacg ctggggcaga caccggaact ccacactgga acaacaaaga agcactggta 1681 gagttcaagg acgcacatgc caaaaggcaa actgtcgtgg ttctagggag tcaagaagga 1741 gcagttcaca cggcccttgc tggagctctg gaggctgaga tggatggtgc aaagggaagg 1801 ctgtcctctg gccacttgaa atgtcgcctg aaaatggata aacttagatt gaagggcgtg 1861 tcatactcct tgtgtaccgc agcgttcaca ttcaccaaga tcccggctga aacactgcac 1921 gggacagtca cagtggaggt acagtacgca gggacagatg gaccttgcaa ggttccagct 1981 cagatggcgg tggacatgca aactctgacc ccagttggga ggttgataac cgccaacccc 2041 gtaatcactg aaagcactga gaactctaag atgatgctgg aacttgatcc accatttggg 2101 gactcttaca ttgtcatagg agtcggggag aagaagatca cccaccactg gcacaggagt 2161 ggcagcacca ttggaaaagc atttgaagcc actgtgagag gtgccaagag aatggcagtc 2221 ttgggagata cagcctggga ctttggatca gttggaggcg ctctcaactc attgggcaag 2281 ggcatccatc aaatttttgg agcagctttc aaatcattgt ttggaggaat gtcctggttc 2341 tcacaaatcc tcattggaac gttgctgatg tggttgggtc tgaacacaaa gaatggatct 2401 atttccctca tgtgcttggc cttaggggga gtgttgatct tcttatccac agccgtctct 2461 gctgatgtgg ggtgctcggt ggacttctca aagaaggaga cgagatgcgg tacaggggtg 2521 ttcgtctata acgacgttga agcctggagg gacaggtaca agtaccatcc tgactccccc 2581 cgtagattgg cagcagcagt caagcaagcc tgggaagatg gtatctgcgg gatctcctct 2641 gtttcaagaa tggaaaacat catgtggaga tcagtagaag gggagctcaa tgcaatcctg 2701 gaagagaatg gagttcaact gacggtcgtt gtgggatctg taaaaaaccc catgtggaga 2761 ggtccacaga gattgcccgt gcctgtgaac gagctgcccc acggctggaa ggcttggggg 2821 aaatcgtact tcgttagagc agcaaagaca aataacagct ttgtcgtgga tggtgacaca 2881 ctgaaggaat gcccactcaa acatagagca tggaacagct ttcttgtgga ggatcatggg 2941 ttcggggtat ttcacactag tgtctggctc aaggttagag aagattattc attagagtgt 3001 gatccagccg ttattggaac agctgttaag ggaaaggagg ctgtacacag tgatctaggc 3061 tactggattg agagtgagaa gaatgacaca tggaggctga agagggccca tctgatcgag 3121 atgaaaacat gtgaatggcc aaagtcccac acattgtgga cagatggaat agaagagagt 3181 gatctgatca tacccaagtc tttagctggg ccactcagcc atcacaatac cagagagggc 3241 tacaggaccc aaatgaaagg gccatggcac agtgaagagc ttgaaattcg gtttgaggaa 3301 tgcccaggca ctaaggtcca cgtggaggaa acatgtggaa caagaggacc atctctgaga 3361 tcaaccactg caagcggaag ggtgatcgag gaatggtgct gcagggagtg cacaatgccc 3421 ccactgtcgt tccgggctaa agatggctgt tggtatggaa tggagataag gcccaggaaa 3481 gaaccagaaa gcaacttagt aaggtcagtg gtgactgcag gatcaactga tcacatggat 3541 cacttctccc ttggagtgct tgtgattctg ctcatggtgc aggaagggct gaagaagaga 3601 atgaccacaa agatcatcat aagcacatca atggcagtgc tggtagctat gatcctggga 3661 ggattttcaa tgggtgacct ggctaagctt gcaattttga tgggtgccac cttcgcggaa 3721 atgaacactg gaggagatgt agctcatctg gcgctgatag cggcattcaa agtcagacca 3781 gcgttgctgg tatctttcat cttcagagct aattggacac cccgtgaaag catgctgctg 3841 gccttggcct cgtgtctttt gcaaactgcg atctccgcct tggaaggcga cctgatggtt 3901 ctcatcaatg gttttgcttt ggcctggttg gcaatacgag cgatggttgt tccacgcact 3961 gataacatca ccttggcaat cctggctgct ctgacaccac tggcccgggg cacactgctt 4021 gtggcgtgga gagcaggcct tgctacttgc ggggggttta tgctcctctc tctgaaggga 4081 aaaggcagtg tgaagaagaa cttaccattt gtcatggccc tgggactaac cgctgtgagg 4141 ctggtcgacc ccatcaacgt ggtgggactg ctgttgctca caaggagtgg gaagcggagc 4201 tggcccccta gcgaagtact cacagctgtt ggcctgatat gcgcattggc tggagggttc 4261 gccaaggcag atatagagat ggctgggccc atggccgcgg tcggtctgct aattgtcagt 4321 tacgtggtct caggaaagag tgtggacatg tacattgaaa gagcaggtga catcacatgg 4381 gaaaaagatg cggaagtcac tggaaacagt ccccggctcg atgtggcgct agatgagagt 4441 ggtgatttct ccctggtgga ggatgacggt ccccccatga gagagatcat actcaaggtg 4501 gtcctgatga ccatctgtgg catgaaccca atagccatac cctttgcagc tggagcgtgg 4561 tacgtatacg tgaagactgg aaaaaggagt ggtgctctat gggatgtgcc tgctcccaag 4621 gaagtaaaaa agggggagac cacagatgga gtgtacagag taatgactcg tagactgcta 4681 ggttcaacac aagttggagt gggagttatg caagaggggg tctttcacac tatgtggcac 4741 gtcacaaaag gatccgcgct gagaagcggt gaagggagac ttgatccata ctggggagat 4801 gtcaagcagg atctggtgtc atactgtggt ccatggaagc tagatgccgc ctgggacggg 4861 cacagcgagg tgcagctctt ggccgtgccc cccggagaga gagcgaggaa catccagact 4921 ctgcccggaa tatttaagac aaaggatggg gacattggag cggttgcgct ggattaccca 4981 gcaggaactt caggatctcc aatcctagac aagtgtggga gagtgatagg actttatggc 5041 aatggggtcg tgatcaaaaa tgggagttat gttagtgcca tcacccaagg gaggagggag 5101 gaagagactc ctgttgagtg cttcgagcct tcgatgctga agaagaagca gctaactgtc 5161 ttagacttgc atcctggagc tgggaaaacc aggagagttc ttcctgaaat agtccgtgaa 5221 gctataaaaa caagactccg tactgtgatc ttagctccaa ccagggttgt cgctgctgaa 5281 atggaggaag cccttagagg gcttccagtg cgttatatga caacagcagt caatgtcacc 5341 cattctggaa cagaaatcgt cgacttaatg tgccatgcca ccttcacttc acgtctacta 5401 cagccaatca gagtccccaa ctataatctg tatattatgg atgaggccca cttcacagat 5461 ccctcaagta tagcagcaag aggatacatt tcaacaaggg ttgagatggg cgaggcggct 5521 gccatcttca tgaccgccac gccaccagga acccgtgacg catttccgga ctccaactca 5581 ccaattatgg acaccgaagt ggaagtccca gagagagcct ggagctcagg ctttgattgg 5641 gtgacggatc attctggaaa aacagtttgg tttgttccaa gcgtgaggaa cggcaatgag 5701 atcgcagctt gtctgacaaa ggctggaaaa cgggtcatac agctcagcag aaagactttt 5761 gagacagagt tccagaaaac aaaacatcaa gagtgggact ttgtcgtgac aaccgacatt 5821 tcagagatgg gcgccaactt taaagctgac cgtgtcatag attccaggag atgcctaaag 5881 ccggtcatac ttgatggcga gagagtcatt ctggctggac ccatgcctgt cacacatgcc 5941 agcgctgccc agaggagggg gcgcataggc aggaatccca acaaacctgg agatgagtat 6001 ctgtatggag gtgggtgcgc agagactgac gaagaccatg cacactggct tgaagcaaga 6061 atgctccttg acaatattta cctccaagat ggcctcatag cctcgctcta tcgacctgag 6121 gccgacaaag tagcagccat tgagggagag ttcaagctta ggacggagca aaggaagacc 6181 tttgtggaac tcatgaaaag aggagatctt cctgtttggc tggcctatca ggttgcatct 6241 gccggaataa cttacacaga tagaagatgg tgctttgatg gcacgaccaa caacaccata 6301 atggaagaca gtgtgccggc agaggtgtgg accagacacg gagagaaaag agtgctcaaa 6361 ccgaggtgga tggacgccag agtttgttca gatcatgcgg ccctgaagtc attcaaggag 6421 tttgccgctg ggaaaagagg agcggctttt ggagtgatgg aagccctggg aacactgcca 6481 ggacacatga cagagagatt ccaggaagcc attgacaacc tcgctgtgct catgcgggca 6541 gagactggaa gcaggcctta caaagccgcg gcggcccaat tgccggagac cctagagacc 6601 attatgcttt tggggttgct gggaacagtc tcgctgggaa tctttttcgt cttgatgagg 6661 aacaagggca tagggaagat gggctttgga atggtgactc ttggggccag cgcatggctc 6721 atgtggctct cggaaattga gccagccaga attgcatgtg tcctcattgt tgtgttccta 6781 ttgctggtgg tgctcatacc tgagccagaa aagcaaagat ctccccagga caaccaaatg 6841 gcaatcatca tcatggtagc agtaggtctt ctaggcttga tcaccgccaa tgaactcgga 6901 tggttggaga gaacaaagag tgacctaagc catctaatgg gaaggagaga ggagggagca 6961 accataggat tctcaatgga cattgacctg cggccagcct cagcttgggc catctatgct 7021 gccttgacaa ctttcattac cccagccgtc caacatgcag tgaccacttc atacaacaac 7081 tactccttaa tggcgatggc cacgcaagct ggagtgttgt ttggtatggg caaagggatg 7141 ccattctacg catgggactt tggagtcccg ctgctaatga taggttgcta ctcacaatta 7201 acacccctga ccctaatagt ggccatcatt ttgctcgtgg cgcactacat gtacttgatc 7261 ccagggctgc aggcagcagc tgcgcgtgct gcccagaaga gaacggcagc tggcatcatg 7321 aagaaccctg ttgtggatgg aatagtggtg actgacattg acacaatgac aattgacccc 7381 caagtggaga aaaagatggg acaggtgcta ctcatagcag tagccgtctc cagcgccata 7441 ctgtcgcgga ccgcctgggg gtggggggag gctggggccc tgatcacagc cgcaacttcc 7501 actttgtggg aaggctctcc gaacaagtac tggaactcct ctacagccac ttcactgtgt 7561 aacattttta ggggaagtta cttggctgga gcttctctaa tctacacagt aacaagaaac 7621 gctggcttgg tcaagagacg tgggggtgga acaggagaga ccctgggaga gaaatggaag 7681 gcccgcttga accagatgtc ggccctggag ttctactcct acaaaaagtc aggcatcacc 7741 gaggtgtgca gagaagaggc ccgccgcgcc ctcaaggacg gtgtggcaac gggaggccat 7801 gctgtgtccc gaggaagtgc aaagctgaga tggttggtgg agcggggata cctgcagccc 7861 tatggaaagg tcattgatct tggatgtggc agagggggct ggagttacta cgccgccacc 7921 atccgcaaag ttcaagaagt gaaaggatac acaaaaggag gccctggtca tgaagaaccc 7981 gtgttggtgc aaagctatgg gtggaacata gtccgtctca agagtggggt ggacgtcttt 8041 catatggcgg ctgagccgtg tgacacgttg ctatgtgaca taggtgagtc atcatctagt 8101 cctgaagtgg aagaagcacg gacgctcaga gtcctctcca tggtggggga ttggcttgaa 8161 aaaagaccag gagccttttg tataaaagtg ttgtgcccat acaccagcac tatgatggaa 8221 accctggagc gactgcagcg taggtatggg ggaggactgg tcagagtgcc actctcccgc 8281 aactctacac atgagatgta ctgggtctct ggagcgaaaa gcaacaccat aaaaagtgtg 8341 tccaccacga gccagctcct cttggggcgc atggacgggc ctaggaggcc agtgaaatat 8401 gaggaggatg tgaatctcgg ctctggcacg cgggctgtgg taagctgcgc tgaagctccc 8461 aacatgaaga tcattggtaa ccgcattgaa aggatccgca gtgagcacgc ggaaacgtgg 8521 ttctttgacg agaaccaccc atataggaca tgggcttacc atggaagcta tgaggccccc 8581 acacaagggt cagcatcctc tctagtaaac ggggttgtca ggctcctgtc aaaaccctgg 8641 gatgtggtga ctggagtcac aggaatagcc atgaccgaca ccacaccgta tggtcagcaa 8701 agagttttca aggaaaaagt ggacactagg gtgccagacc cccaagaagg cactcgtcag 8761 gttatgagca tggtctcttc ctggttgtgg aaagagctag gcaaacacaa acggccacga 8821 gtctgtacca aagaagagtt catcaacaag gttcgtagca acgcagcatt aggggcaata 8881 tttgaagagg aaaaagagtg gaagactgca gtggaagctg tgaacgatcc aaggttctgg 8941 gctctagtgg acaaggaaag agagcaccac ctgagaggag agtgccagag ttgtgtgtac 9001 aacatgatgg gaaaaagaga aaagaaacaa ggggaatttg gaaaggccaa gggcagccgc 9061 gccatctggt atatgtggct aggggctaga tttctagagt tcgaagccct tggattcttg 9121 aacgaggatc actggatggg gagagagaac tcaggaggtg gtgttgaagg gctgggatta 9181 caaagactcg gatatgtcct agaagagatg agtcgcatac caggaggaag gatgtatgca 9241 gatgacactg ctggctggga tacccgcatc agcaggtttg atctagagaa tgaagctcta 9301 atcaccaacc aaatggagaa agggcacagg gccttggcat tggccataat caagtacaca 9361 taccaaaaca aagtggtaaa ggtccttaga ccagctgaaa aagggaaaac agttatggac 9421 attatttcga gacaagacca aagggggagc ggacaagttg tcacttacgc tcttaacaca 9481 tttaccaacc tagtggtgca actcattcgg aatatggagg ctgaggaagt tctagagatg 9541 caagacttgt ggctgctgcg gaggtcagag aaagtgacca actggttgca gagcaacgga 9601 tgggataggc tcaaacgaat ggcagtcagt ggagatgatt gcgttgtgaa gccaattgat 9661 gataggtttg cacatgccct caggttcttg aatgatatgg gaaaagttag gaaggacaca 9721 caagagtgga aaccctcaac tggatgggac aactgggaag aagttccgtt ttgctcccac 9781 cacttcaaca agctccatct caaggacggg aggtccattg tggttccctg ccgccaccaa 9841 gatgaactga ttggtcgggc ccgcgtctct ccaggggcgg gatggagcat ccgggagact 9901 gcttgcctag caaaatcata tgcgcaaatg tggcagctcc tttatttcca cagaagggac 9961 ctccgactga tggccaatgc catttgttca tctgtgccag ttgactgggt tccaactggg 10021 agaactacct ggtcaatcca tggaaaggga gaatggatga ccattgaaga catgcttgtg 10081 gtgtggaaca gagtgtggat tgaggagaac gaccacatgg aagacaagac cccagttacg 10141 aaatggacag acattcccta tttgggaaaa agggaagact tgtggtgtgg atctctcata 10201 gggcacagac cgcgcaccac ctgggctgag aacattaaaa acacagtcaa catggtgcgc 10261 aggatcatag gtgaggaaga aaagtacatg gactacctat ccacccaagt ccgctacttg 10321 ggtgaagaag ggtctacacc tggagtgctg taagcaccaa tctta

1. Zika virus isolate ZIKV/Homo_sapiens/USA/2016/FL021U polyprotein gene, complete cds 10,365 bp linear RNA Accession: KX922703.1 GI: 1071930510 GenBankFASTAGraphics Select item 10719305122. Zika virus isolate ZIKV/Homo_sapiens/USA/2016/FL030U polyprotein gene, complete cds 10,609 bp linear RNA Accession: KX922704.1 GI: 1071930512 GenBankFASTAGraphics Select item 10719305143. Zika virus isolate ZIKV/Homo_sapiens/USA/2016/FL032U polyprotein gene, complete cds 10,609 bp linear RNA Accession: KX922705.1 GI: 1071930514 GenBankFASTAGraphics Select item 10719305164. Zika virus isolate ZIKV/Homo_sapiens/USA/2016/FL038U polyprotein gene, complete cds 10,610 bp linear RNA Accession: KX922706.1 GI: 1071930516 GenBankFASTAGraphics Select item 10719305185. Zika virus isolate ZIKV/Homo_sapiens/USA/2016/FL039U polyprotein gene, complete cds 10,609 bp linear RNA Accession: KX922707.1 GI: 1071930518 GenBankFASTAGraphics Select item 10719305206. Zika virus isolate ZIKV/Aedes_aegypti/USA/2016/FL04M polyprotein gene, complete cds 10,606 bp linear RNA Accession: KX922708.1 GI: 1071930520 GenBankFASTAGraphics

Correspondence with Broad sequences Broad ID Scripps ID USA_2016_FL-010_URI ZF10 USA_2016_FL-030_URI ZF30 USA_2016_FL-032_URI ZF32 USA_2016_FL-038_URI ZF38 USA_2016_FL-039_URI ZF39 USA_2016_FL-01_MOS ZM1 USA_2016_FL-02_MOS ZM2 USA_2016_FL-03_MOS ZM3 USA_2016_FL-04_MOS ZM4

Sequence MetaData Scripps ID Patient ID Sample type Quality score % Coverage Average Depth Onset Collection Days post onset Local or travel Location of infection GE/ul RNA GE/mL sample Sequencing status Consensus name Merged Bam File ZF1 001 Saliva *** 99.71 46616.27 2016.03.18 2016.03.22 4 Travel Martinique 11 3.3E+03 coding-complete ZF1_01Sa_XX_2016-03-22 usa_ex_martinique ZF1.c1.Sa.a1.l1.l3.l4.r1 ZF8 008 Urine *** 90.07 35012.49 2016.06.15 2016.06.21 6 Travel Puerto Rico 4 1.1E+03 coding-complete ZF8_08U_XX_2016-06-21 usa_ex_puerto_rico ZF8.c1.UR.a1.l1.l2.r1 ZF10 010 Urine **** 97.69 55330.48 2016.06.17 2016.06.22 5 Local? USA 213 6.1E+04 coding-complete ZF10_10U_KX842499 2016-06-22 usa_ex_USA ZF10.c1.UR.a1.l1.r1 ZF16 016 Urine *** 99.88 75158.72 2016.06.28 2016.07.03 5 Travel Puerto Rico 14 4.0E+03 coding-complete ZF16_16U_XX_2016-07-03 usa_ex_puerto_rico ZF16.c1.UR.a1.l1.l2.l3.l4.l5.r1 ZF21 021 Urine *** 97.45 52361.36 2016.07.09 2016.07.19 10 Local USA 50 1.4E+04 coding-complete ZF21_21U_XX_2016-07-19 usa ZF21.c1.UR.a1.l1.l2.l3.r1 ZF22 022 Urine *** 97.77 51135.60 2016.07.16 2016.07.16 6 Local USA 11 3.0E+03 coding-complete ZF22_22U_XX_2016-07-16 usa ZF22.c1.UR.a1.l1.l2.l3.l4.r1 ZF30 030 Urine *** 99.75 57779.63 2016.07.31 2016.08.02 2 Local USA 36 1.0E+04 coding-complete ZF30_30U_XX_2016-08-02 usa ZF30.c1.UR.a1.l1.l2.l3.r1 ZF32 032 Urine *** 99.75 51483.94 2016.07.29 2016.08.05 7 Local USA 75 2.1E+04 coding-complete ZF32_32U_XX_2016-08-05 usa ZF32.c1.UR.a1.l1.l2.l3.r1 ZF38 038 Urine *** 99.76 81750.77 2016.08.04 2016.08.05 1 Local USA 38 1.1E+04 coding-complete ZF38_38U_XX_2016-08-05 usa ZF38.c1.UR.a1.l1.l2.l3.l4.r1 ZF39 039 Urine **** 99.75 70253.99 2016.08.12 2016.08.17 5 Local USA 1276 3.6E+05 coding-complete ZF39_39U_XX_2016-08-17 usa ZF39.c1.UR.a1.l1.l2.l3.r1 ZL2 Hu0015 Saliva *** 99.75 89934.25 2016.08.19 2016.08.24 5 Local USA 38 21610.23 coding-complete ZL2_Hu0015_KX832731 2016-08-22 usa ZL2.c1.SA.a1.l1.l2.r1 ZM1 7501 Mosquito **** 99.75 141038.31 2016.08.22 Local USA 4563 9.1E+06 coding-complete Ae-aegypti_ZM1_7501_KX838904_2016-08-22_usa ZM1.c1.MO.a1.l1.l2.r1 ZM2 7719 Mosquito **** 99.74 137263.85 2016.08.23 Local USA 279 5.6E+05 coding-complete Ae-aegypti_ZM2_7719_KX838905_2016-08-23_usa ZM2.c1.MO.a1.l1.l2.r1 ZM3 7727 Mosquito **** 99.83 139787.57 2016.08.23 Local USA 22549 4.5E+07 coding-complete Ae-aegypti_ZM3_7727_KX838906_2016-08-23_usa ZM3.c1.MO.a1.l1.l2.r1 ZM4 16-10416 Mosquito **** 99.72 45505.39 2016.09.04 Local USA 102 4.4E+04 coding-complete Ae-aegypti_ZM4_16-10416_XX_2016-09-04_usa ZM4.c1.MO.a1.l1.l2.r1 ZM5 16-3125 Mosquito ** 96.63 5365.36 2016.09.09 Local USA 447 1.9E+05 missing part of 5' Ae-aegypti_ZM5_16-3125_XX_2016-09-09_usa ZM5.c1.MO.a1.l1.l2.r1 ZC188 423568715 Serum **** 98.26 29394.90 2016.01.16 Columbia 36 1.5E+04 coding-complete ZC188_423568715_XX_2016-01-16_colombia ZC188.c1.SR.a1.l3.l4.r1 ZC192 423401315 Serum **** 98.36 30396.29 2016.01.07 Columbia 39 1.7E+04 coding-complete ZC192_423401315_XX_2016-01-07_colombia ZC192.c1.SR.a1.l3.l4.r1 ZC204 424439915 Serum **** 99.74 29003.25 2016.01.06 Columbia 48 2.1E+04 coding-complete ZC204_424439915_XX_2016-01-05_colombia ZC204.c1.SR.a1.l1.l2.r1 ZC207 423217515 Serum **** 96.68 19477.70 2016.01.09 Columbia 16 6.7E+04 coding-complete ZC207_423217515_XX_2016-01-09_colombia ZC207.c1.SR.a1.l1.l2.r1 Quality **** Complete coding sequence, no apparent contamination in aligned bam file *** Complete coding sequence, some contamination in aligned bam file (confident in consensus) ** Partial coding sequence, no apparent contamination in aligned bam file * Partial coding sequence, some contamination in aligned bam file https://github.com/andersen-lab/zika-florida/tree/master/consensus_sequences

Most of the Florida Zika sequences posted at the Andersen lab at Scripps Clinic are now published at Genbak. Included is ZM4 (fourth Miami Beach sequence from mosquito batches) and ZF39 (sequence from Pinellas case, who had no recent travel outside of Pinellas or Hillsborough Counties.

Sequences producing significant alignments: Select:AllNone Selected:0 AlignmentsDownloadGenBankGraphicsDistance tree of resultsShow/hide columns of the table presenting sequences producing significant alignments Sequences producing significant alignments: Select for downloading or viewing reports Description Max score Total score Query cover E value Ident Accession Select seq gb|KX838906.1| Zika virus isolate ZIKV/Aedes_aegypti/USA/2016/ZM3-7729 polyprotein gene, complete cds 18493 18493 100% 0.0 99% KX838906.1 Select seq gb|KX673530.1| Zika virus isolate PHE_semen_Guadeloupe, complete genome 18420 18420 100% 0.0 99% KX673530.1 Select seq gb|KU853013.1| Zika virus isolate Dominican Republic/2016/PD2, complete genome 18417 18417 100% 0.0 99% KU853013.1 Select seq gb|KU853012.1| Zika virus isolate Dominican Republic/2016/PD1, complete genome 18415 18415 100% 0.0 99% KU853012.1 Select seq gb|KX842449.1| Zika virus isolate ZIKV/Human/USA/2016/ZF10.UR-010 polyprotein gene, complete cds 18408 18408 100% 0.0 99% KX842449.1 Select seq gb|KX838905.1| Zika virus isolate ZIKV/Aedes_aegypti/USA/2016/ZM2-7719 polyprotein gene, complete cds 18402 18402 100% 0.0 99% KX838905.1 Select seq gb|KX838904.1| Zika virus isolate ZIKV/Aedes_aegypti/USA/2016/ZM1-7501 polyprotein gene, complete cds 18399 18399 100% 0.0 99% KX838904.1 Select seq gb|KX832731.1| Zika virus isolate ZIKV/Human/USA/2016/ZL2.SA-Hu0015 polyprotein gene, complete cds 18399 18399 100% 0.0 99% KX832731.1 Select seq gb|KX447510.1| Zika virus isolate 1_0049_PF polyprotein gene, complete cds 18327 18327 100% 0.0 99% KX447510.1 Select seq gb|KX280026.1| Zika virus isolate Paraiba_01, complete genome 18321 18321 100% 0.0 99% KX280026.1 Select seq gb|KU729217.2| Zika virus isolate BeH823339 polyprotein gene, complete cds 18321 18321 100% 0.0 99% KU729217.2 Select seq gb|KX447512.1| Zika virus isolate 1_0181_PF polyprotein gene, complete cds 18318 18318 100% 0.0 99% KX447512.1 Select seq gb|KX369547.1| Zika virus strain PF13/251013-18, complete genome 18318 18318 100% 0.0 99% KX369547.1 Select seq gb|KU509998.3| Zika virus strain Haiti/1225/2014, complete genome 18318 18318 100% 0.0 99% KU509998.3 Select seq gb|KJ776791.2| Zika virus strain H/PF/2013, complete genome 18312 18312 100% 0.0 99% KJ776791.2 Select seq gb|KX447509.1| Zika virus isolate 1_0087_PF polyprotein gene, complete cds 18312 18312 100% 0.0 99% KX447509.1 Select seq gb|KU991811.1| Zika virus isolate Brazil/2016/INMI1 polyprotein gene, complete cds 18312 18312 100% 0.0 99% KU991811.1 Select seq gb|KX447513.1| Zika virus isolate 1_0134_PF polyprotein gene, complete cds 18309 18309 100% 0.0 99% KX447513.1 Select seq gb|KX811222.1| Zika virus isolate Brazil_2015_MG, complete genome 18303 18303 100% 0.0 99% KX811222.1 Select seq gb|KX197205.1| Zika virus isolate 9, complete genome 18303 18303 100% 0.0 99% KX197205.1 Select seq gb|KX447515.1| Zika virus isolate 1_0030_PF polyprotein gene, complete cds 18303 18303 100% 0.0 99% KX447515.1 Select seq gb|KX447511.1| Zika virus isolate 1_0015_PF polyprotein gene, complete cds 18303 18303 100% 0.0 99% KX447511.1 Select seq gb|KU321639.1| Zika virus strain ZikaSPH2015, complete genome 18303 18303 100% 0.0 99% KU321639.1 Select seq gb|KX879604.1| Zika virus isolate SN089, complete genome 18300 18300 100% 0.0 99% KX879604.1 Select seq gb|KX447514.1| Zika virus isolate 1_0035_PF polyprotein gene, complete cds 18300 18300 100% 0.0 99% KX447514.1 Select seq gb|KX051563.1| Zika virus isolate Haiti/1/2016, complete genome 18300 18300 100% 0.0 99% KX051563.1 Select seq gb|KX447516.1| Zika virus isolate 1_0111_PF polyprotein gene, complete cds 18294 18294 100% 0.0 99% KX447516.1 Select seq gb|KU729218.1| Zika virus isolate BeH828305 polyprotein gene, complete cds 18294 18294 100% 0.0 99% KU729218.1 Select seq gb|KU707826.1| Zika virus isolate SSABR1, complete genome 18294 18294 100% 0.0 99% KU707826.1 Select seq gb|KU527068.1| Zika virus strain Natal RGN, complete genome 18294 18294 100% 0.0 99% KU527068.1 Select seq gb|KU365779.1| Zika virus strain BeH819966 polyprotein gene, complete cds 18294 18294 100% 0.0 99% KU365779.1 Select seq gb|KX879603.1| Zika virus isolate SN062, complete genome 18291 18291 100% 0.0 99% KX879603.1 Select seq gb|KX262887.1| Zika virus isolate 103451, complete genome 18291 18291 100% 0.0 99% KX262887.1 Select seq gb|KX197192.1| Zika virus isolate ZIKV/H.sapiens/Brazil/PE243/2015, complete genome 18291 18291 100% 0.0 99% KX197192.1 Select seq gb|KU926310.1| Zika virus isolate Rio-S1, complete genome 18291 18291 100% 0.0 99% KU926310.1 Select seq gb|KU926309.1| Zika virus isolate Rio-U1, complete genome 18291 18291 100% 0.0 99% KU926309.1 Select seq gb|KU940228.1| Zika virus isolate Bahia07, partial genome 18285 18285 100% 0.0 99% KU940228.1 Select seq gb|KX694534.1| Zika virus strain ZIKV/Homo sapiens/HND/R103451/2015, complete genome 18282 18282 100% 0.0 99% KX694534.1 Select seq gb|KX447517.1| Zika virus isolate 1_0038_PF polyprotein gene, complete cds 18282 18282 100% 0.0 99% KX447517.1 Select seq gb|KX247646.1| Zika virus isolate Zika virus/Homo sapiens/COL/UF-1/2016, complete genome 18282 18282 100% 0.0 99% KX247646.1 Select seq gb|KX198135.1| Zika virus strain ZIKV/Homo sapiens/PAN/BEI-259634_V4/2016, complete genome 18282 18282 100% 0.0 99% KX198135.1 Select seq gb|KX156776.1| Zika virus strain ZIKV/Homo sapiens/PAN/CDC-259364_V1-V2/2015, complete genome 18282 18282 100% 0.0 99% KX156776.1 Select seq gb|KU501217.1| Zika virus strain 8375 polyprotein gene, complete cds 18282 18282 100% 0.0 99% KU501217.1 Select seq gb|KU365780.1| Zika virus strain BeH815744 polyprotein gene, complete cds 18282 18282 100% 0.0 99% KU365780.1 Select seq gb|KX156774.1| Zika virus strain ZIKV/Homo sapiens/PAN/CDC-259359_V1-V3/2015, complete genome 18276 18276 100% 0.0 99% KX156774.1 Select seq gb|KU647676.1| Zika virus strain MRS_OPY_Martinique_PaRi_2015 polyprotein gene, complete cds 18276 18276 100% 0.0 99% KU647676.1 Select seq gb|KU501216.1| Zika virus strain 103344 polyprotein gene, complete cds 18276 18276 100% 0.0 99% KU501216.1 Select seq gb|KU365777.1| Zika virus strain BeH818995 polyprotein gene, complete cds 18276 18276 100% 0.0 99% KU365777.1 Select seq gb|KU820897.5| Zika virus isolate FLR polyprotein gene, complete cds 18273 18273 100% 0.0 99% KU820897.5 Select seq gb|KU758877.1| Zika virus isolate 17271 polyprotein gene, complete cds 18273 18273 100% 0.0 99% KU758877.1 Select seq gb|KX247632.1| Zika virus isolate MEX_I_7 polyprotein gene, complete cds 18273 18273 100% 0.0 99% KX247632.1 Select seq gb|KX156775.1| Zika virus strain ZIKV/Homo sapiens/PAN/CDC-259249_V1-V3/2015, complete genome 18273 18273 100% 0.0 99% KX156775.1 Select seq gb|KX087102.1| Zika virus strain ZIKV/Homo sapiens/COL/FLR/2015, complete genome 18273 18273 100% 0.0 99% KX087102.1 Select seq gb|KU497555.1| Zika virus isolate Brazil-ZKV2015, complete genome 18269 18269 99% 0.0 99% KU497555.1 Select seq gb|KX520666.1| Zika virus isolate HS-2015-BA-01 polyprotein gene, complete cds 18267 18267 100% 0.0 99% KX520666.1 Select seq gb|KX856011.1| Zika virus strain ZIKV/Aedes sp./MEX_I-44/2016, complete genome 18264 18264 100% 0.0 99% KX856011.1 Select seq gb|KX446951.1| Zika virus strain ZIKV/Aedes.sp/MEX/MEX_I-7/2016, complete genome 18264 18264 100% 0.0 99% KX446951.1 Select seq gb|KU501215.1| Zika virus strain PRVABC59, complete genome 18264 18264 100% 0.0 99% KU501215.1 Select seq gb|KU365778.1| Zika virus strain BeH819015 polyprotein gene, complete cds 18264 18264 100% 0.0 99% KU365778.1 Select seq gb|KU312312.1| Zika virus isolate Z1106033 polyprotein gene, complete cds 18264 18264 100% 0.0 99% KU312312.1 Select seq gb|KX601168.1| Zika virus strain ZIKV/Homo Sapiens/PRI/PRVABC59/2015, complete genome 18258 18258 100% 0.0 99% KX601168.1 Select seq gb|KX446950.1| Zika virus strain ZIKV/Aedes.sp/MEX/MEX_2-81/2016, complete genome 18258 18258 100% 0.0 99% KX446950.1 Select seq gb|KX087101.2| Zika virus strain ZIKV/Homo sapiens/PRI/PRVABC59/2015, complete genome 18258 18258 100% 0.0 99% KX087101.2 Select seq gb|KU922960.1| Zika virus isolate MEX/InDRE/Sm/2016, complete genome 18258 18258 100% 0.0 99% KU922960.1 Select seq gb|KX806557.1| Zika virus isolate TS17-2016, complete genome 18254 18254 100% 0.0 99% KX806557.1 Select seq gb|KX702400.1| Zika virus strain Zika virus/Homo sapiens/VEN/UF-1/2016, complete genome 18254 18254 100% 0.0 99% KX702400.1 Select seq gb|KX548902.1| Zika virus isolate ZIKV/COL/FCC00093/2015 polyprotein gene, complete cds 18254 18254 100% 0.0 99% KX548902.1 Select seq gb|KX377337.1| Zika virus strain PRVABC-59, complete genome 18254 18254 100% 0.0 99% KX377337.1 Select seq gb|KU937936.1| Zika virus isolate ZIKVNL00013 polyprotein gene, complete cds 18254 18254 100% 0.0 99% KU937936.1 Select seq gb|KU922923.1| Zika virus isolate MEX/InDRE/Lm/2016, complete genome 18254 18254 100% 0.0 99% KU922923.1 Select seq gb|KU870645.1| Zika virus isolate FB-GWUH-2016, complete genome 18249 18249 100% 0.0 99% KU870645.1 Select seq gb|KX766029.1| Zika virus isolate R116265, complete genome 18245 18245 100% 0.0 99% KX766029.1 Select seq gb|KU820898.1| Zika virus isolate GZ01 polyprotein gene, complete cds 18236 18236 100% 0.0 99% KU820898.1 Select seq gb|KX056898.1| Zika virus isolate Zika virus/GZ02/2016 polyprotein gene, complete cds 18231 18231 100% 0.0 99% KX056898.1 Select seq gb|KU955590.1| Zika virus isolate Z16019 polyprotein gene, complete cds 18231 18231 100% 0.0 99% KU955590.1 Select seq gb|KX766028.1| Zika virus isolate R114916, complete genome 18229 18229 100% 0.0 99% KX766028.1 Select seq gb|KU740184.2| Zika virus isolate GD01 polyprotein gene, complete cds 18227 18227 100% 0.0 99% KU740184.2 Select seq gb|KU761564.1| Zika virus isolate GDZ16001 polyprotein gene, complete cds 18227 18227 100% 0.0 99% KU761564.1 Select seq gb|KX117076.1| Zika virus isolate Zhejiang04, complete genome 18222 18222 100% 0.0 99% KX117076.1 Select seq gb|KX185891.1| Zika virus isolate Zika virus/CN/SZ02/2016 polyprotein gene, complete cds 18213 18213 100% 0.0 99% KX185891.1 Select seq gb|KU963796.1| Zika virus isolate SZ-WIV01 polyprotein gene, complete cds 18213 18213 100% 0.0 99% KU963796.1 Select seq gb|KX253996.1| Zika virus isolate ZKC2/2016, complete genome 18209 18209 100% 0.0 99% KX253996.1 Select seq gb|KU955589.1| Zika virus isolate Z16006 polyprotein gene, complete cds 18209 18209 100% 0.0 99% KU955589.1 Select seq gb|KU820899.2| Zika virus isolate ZJ03, complete genome 18209 18209 100% 0.0 99% KU820899.2 Select seq gb|KX266255.1| Zika virus isolate ZIKV_SMGC-1, complete genome 18206 18206 100% 0.0 99% KX266255.1 Select seq gb|KU866423.2| Zika virus isolate Zika virus/SZ01/2016/China polyprotein gene, complete cds 18204 18204 100% 0.0 99% KU866423.2 Select seq gb|KU940224.1| Zika virus isolate Bahia09, partial genome 18191 18191 99% 0.0 99% KU940224.1 Select seq gb|KU744693.1| Zika virus isolate VE_Ganxian, complete genome 18069 18069 100% 0.0 99% KU744693.1 Select seq gb|KX827309.1| Zika virus isolate ZKA-16-291 polyprotein gene, complete cds 18056 18056 100% 0.0 99% KX827309.1 Select seq gb|KX813683.1| Zika virus isolate ZKA-16-097 polyprotein gene, complete cds 18042 18042 100% 0.0 99% KX813683.1 Select seq gb|KU681081.3| Zika virus isolate Zika virus/H.sapiens-tc/THA/2014/SV0127- 14, complete genome 17988 17988 100% 0.0 99% KU681081.3 Select seq gb|KX694532.1| Zika virus strain ZIKV/Homo sapiens/THA/PLCal_ZV/2013, complete genome 17867 17867 100% 0.0 99% KX694532.1 Select seq gb|KU955593.1| Zika virus isolate Zika virus/H.sapiens-tc/KHM/2010/FSS13025, complete genome 17672 17672 100% 0.0 98% KU955593.1 Select seq gb|JN860885.1| Zika virus isolate FSS13025 polyprotein gene, partial cds 17672 17672 99% 0.0 98% JN860885.1 Select seq gb|KF993678.1| Zika virus strain PLCal_ZV from Canada polyprotein gene, partial cds 17634 17634 98% 0.0 99% KF993678.1 Select seq gb|EU545988.1| Zika virus polyprotein gene, complete cds 17526 17526 100% 0.0 98% EU545988.1 Select seq gb|KU681082.3| Zika virus isolate Zika virus/H.sapiens-tc/PHL/2012/CPC-0740, complete genome 17380 17380 100% 0.0 98% KU681082.3 Select seq gb|KX601167.1| Zika virus strain ZIKV/Aedes sp./MYS/P6-740/1966, complete genome 16361 16361 100% 0.0 95% KX601167.1 Select seq gb|KX694533.1| Zika virus strain ZIKV/Aedes aegypti/MYS/P6-740/1966, complete genome 16352 16352 100% 0.0 95% KX694533.1 Select seq gb|HQ234499.1| Zika virus isolate P6-740 polyprotein gene, partial cds 16352 16352 99% 0.0 95% HQ234499.1

LOCUS KX922708 10606 bp RNA linear VRL 05-OCT-2016 DEFINITION Zika virus isolate ZIKV/Aedes_aegypti/USA/2016/FL04M polyprotein gene, complete cds. ACCESSION KX922708 VERSION KX922708.1 GI:1071930520 DBLINK BioProject: PRJNA342539 BioSample: SAMN05853067 KEYWORDS . SOURCE Zika virus ORGANISM Zika virus Viruses; ssRNA viruses; ssRNA positive-strand viruses, no DNA stage; Flaviviridae; Flavivirus. REFERENCE 1 (bases 1 to 10606) AUTHORS Grubaugh,N., Paul,L., Porcelli,M., Vasquez,C., Gangavarupu,K., Oliveira,G., Robles-Sikisaka,R., Michael,S., Isern,S. and Andersen,K. TITLE Zika virus sequences from Florida, USA, 2016 JOURNAL Unpublished REFERENCE 2 (bases 1 to 10606) AUTHORS Grubaugh,N., Paul,L., Porcelli,M., Vasquez,C., Gangavarupu,K., Oliveira,G., Robles-Sikisaka,R., Michael,S., Isern,S. and Andersen,K. TITLE Direct Submission JOURNAL Submitted (29-SEP-2016) Department of Immunology and Microbial Science, The Scripps Research Institute, 10550 North Torrey Pines Road, IMM-210, La Jolla, CA 92037, USA COMMENT ##Assembly-Data-START## Assembly Method :: NovoAlign v. V3.04 Sequencing Technology :: Illumina ##Assembly-Data-END## FEATURES Location/Qualifiers source 1..10606 /organism="Zika virus" /mol_type="genomic RNA" /isolate="ZIKV/Aedes_aegypti/USA/2016/FL04M" /isolation_source="pool of 50 adult mosquitoes" /host="Aedes aegypti" /db_xref="taxon:64320" /country="USA: Miami, Florida" /collection_date="04-Sep-2016" CDS 81..10352 /codon_start=1 /product="polyprotein" /protein_id="AOS90225.1" /db_xref="GI:1071930521" /translation="MKNPKKKSGGFRIVNMLKRGVARVSPFGGLKRLPAGLLLGHGPI RMVLAILAFLRFTAIKPSLGLINRWGSVGKKEAMEIIKKFKKDLAAMLRIINARKEKK RRGADTSVGIVGLLLTTAMAAEVTRRGSAYYMYLDRNDAGEAISFPTTLGMNKCYIQI MDLGHMCDATMSYECPMLDEGVEPDDVDCWCNTTSTWVVYGTCHHKKGEARRSRRAVT LPSHSTRKLQTRSQTWLESREYTKHLIRVENWIFRNPGFALAAAAIAWLLGSSTSQKV IYLVMILLIAPAYSIRCIGVSNRDFVEGMSGGTWVDVVLEHGGCVTVMAQDKPTVDIE LVTTTVSNMAEVRSYCYEASISDMASDSRCPTQGEAYLDKQSDTQYVCKRTLVDRGWG NGCGLFGKGSLVTCAKFACSKKMTGKSIQPENLEYRIMLSVHGSQHSGMIVNDTGHET DENRAKVEITPNSPRAEATLGGFGSLGLDCEPRTGLDFSDLYYLTMNNKHWLVHKEWF HDIPLPWHAGADTGTPHWNNKEALVEFKDAHAKRQTVVVLGSQEGAVHTALAGALEAE MDGAKGRLSSGHLKCRLKMDKLRLKGVSYSLCTAAFTFTKIPAETLHGTVTVEVQYAG TDGPCKVPAQMAVDMQTLTPVGRLITANPVITESTENSKMMLELDPPFGDSYIVIGVG EKKITHHWHRSGSTIGKAFEATVRGAKRMAVLGDTAWDFGSVGGALNSLGKGIHQIFG AAFKSLFGGMSWFSQILIGTLLMWLGLNTKNGSISLMCLALGGVLIFLSTAVSADVGC SVDFSKKETRCGTGVFVYNDVEAWRDRYKYHPDSPRRLAAAVKQAWEDGICGISSVSR MENIMWRSVEGELNAILEENGVQLTVVVGSVKNPMWRGPQRLPVPVNELPHGWKAWGK SYFVRAAKTNNSFVVDGDTLKECPLKHRAWNSFLVEDHGFGVFHTSVWLKVREDYSLE CDPAVIGTAVKGKEAVHSDLGYWIESEKNDTWRLKRAHLIEMKTCEWPKSHTLWTDGI EESDLIIPKSLAGPLSHHNTREGYRTQMKGPWHSEELEIRFEECPGTKVHVEETCGTR GPSLRSTTASGRVIEEWCCRECTMPPLSFRAKDGCWYGMEIRPRKEPESNLVRSVVTA GSTDHMDHFSLGVLVILLMVQEGLKKRMTTKIIISTSMAVLVAMILGGFSMSDLAKLA ILMGATFAEMNTGGDVAHLALIAAFKVRPALLVSFIFRANWTPRESMLLALASCLLQT AISALEGDLMVLINGFALAWLAIRAMVVPRTDNITLAILAALTPLARGTLLVAWRAGL ATCGGFMLLSLKGKGSVKKNLPFVMALGLTAVRLVDPINVVGLLLLTRSGKRSWPPSE VLTAVGLICALAGGFAKADIEMAGPMAAVGLLIVSYVVSGKSVDMYIERAGDITWEKD AEVTGNSPRLDVALDESGDFSLVEDDGPPMREIILKVVLMTICGMNPIAIPFAAGAWY VYVKTGKRSGALWDVPAPKEVKKGETTDGVYRVMTRRLLGSTQVGVGVMQEGVFHTMW HVTKGSALRSGEGRLDPYWGDVKQDLVSYCGPWKLDAAWDGHSEVQLLAVPPGERARN IQTLPGIFKTKDGDIGAVALDYPAGTSGSPILDKCGRVIGLYGNGVVIKNGSYVSAIT QGRREEETPVECFEPSMLKKKQLTVLDLHPGAGKTRRVLPEIVREAIKTRLRTVILAP TRVVAAEMEEALRGLPVRYMTTAVNVTHSGTEIVDLMCHATFTSRLLQPIRVPNYNLY IMDEAHFTDPSSIAARGYISTRVEMGEAAAIFMTATPPGTRDAFPDSNSPIMDTEVEV PERAWSSGFDWVTDHSGKTVWFVPSVRNGNEIAACLTKAGKRVIQLSRKTFETEFQKT KHQEWDFVVTTDISEMGANFKADRVIDSRRCLKPVILDGERVILAGPMPVTHASAAQR RGRIGRNPNKPGDEYLYGGGCAETDEDHAHWLEARMLLDNIYLQDGLIASLYRPEADK VAAIEGEFKLRTEQRKTFVELMKRGDLPVWLAYQVASAGITYTDRRWCFDGTTNNTIM EDSVPAEVWTRHGEKRVLKPRWMDARVCSDHAALKSFKEFAAGKRGAAFGVMEALGTL PGHMTERFQEAIDNLAVLMRAETGSRPYKAAAAQLPETLETIMLLGLLGTVSLGIFFV LMRNKGIGKMGFGMVTLGASAWLMWLSEIEPARIACVLIVVFLLLVVLIPEPEKQRSP QDNQMAIIIMVAVGLLGLITANELGWLERTKSDLSHLMGRREEGATIGFSMDIDLRPA SAWAIYAALTTFITPAVQHAVTTSYNNYSLMAMATQAGVLFGMGKGMPFYAWDFGVPL LMIGCYSQLTPLTLIVAIILLVAHYMYLIPGLQAAAARAAQKRTAAGIMKNPVVDGIV VTDIDTMTIDPQVEKKMGQVLLIAVAVSSAILSRTAWGWGEAGALITAATSTLWEGSP NKYWNSSTATSLCNIFRGSYLAGASLIYTVTRNAGLVKRRGGGTGETLGEKWKARLNQ MSALEFYSYKKSGITEVCREEARRALKDGVATGGHAVSRGSAKLRWLVERGYLQPYGK VIDLGCGRGGWSYYAATIRKVQEVKGYTKGGPGHEEPVLVQSYGWNIVRLKSGVDVFH MAAEPCDTLLCDIGESSSSPEVEEARTLRVLSMVGDWLEKRPGAFCIKVLCPYTSTMM ETLERLQRRYGGGLVRVPLSRNSTHEMYWVSGAKSNTIKSVSTTSQLLLGRMDGPRRP VKYEEDVNLGSGTRAVVSCAEAPNMKIIGNRIERIRSEHAETWFFDENHPYRTWAYHG SYEAPTQGSASSLVNGVVRLLSKPWDVVTGVTGIAMTDTTPYGQQRVFKEKVDTRVPD PQEGTRQVMSMVSSWLWKELGKHKRPRVCTKEEFINKVRSNAALGAIFEEEKEWKTAV EAVNDPRFWALVDKEREHHLRGECQSCVYNMMGKREKKQGEFGKAKGSRAIWYMWLGA RFLEFEALGFLNEDHWMGRENSGGGVEGLGLQRLGYVLEEMSRIPGGRMYADDTAGWD TRISRFDLENEALITNQMEKGHRALALAIIKYTYQNKVVKVLRPAEKGKTVMDIISRQ DQRGSGQVVTYALNTFTNLVVQLIRNMEAEEVLEMQDLWLLRRSEKVTNWLQSNGWDR LKRMAVSGDDCVVKPIDDRFAHALRFLNDMGKVRKDTQEWKPSTGWDNWEEVPFCSHH FNKLHLKDGRSIVVPCRHQDELIGRARVSPGAGWSIRETACLAKSYAQMWQLLYFHRR DLRLMANAICSSVPVDWVPTGRTTWSIHGKGEWMTIEDMLVVWNRVWIEENDHMEDKT PVTKWTDIPYLGKREDLWCGSLIGHRPRTTWAENIKNTVNMVRRIIGEEEKYMDYLST QVRYLGEEGSTPGVL" ORIGIN 1 cgacagttcg agtttgaagc gaaagctagc aacagtatca acaggtttta ttttggattt 61 ggaaacgaga gtttctggtc atgaaaaacc caaaaaagaa atccggagga ttccggattg 121 tcaatatgct aaaacgcgga gtagcccgtg tgagcccctt tgggggcttg aagaggctgc 181 cagccggact tctgctgggt catgggccca tcaggatggt cttggcgatt ctagcctttt 241 tgagattcac ggcaatcaag ccatcactgg gtctcatcaa tagatggggt tcagtgggga 301 aaaaagaggc tatggaaata ataaagaagt tcaagaaaga tctggctgcc atgctgagaa 361 taatcaatgc taggaaggag aagaagagac gaggcgcaga tactagtgtc ggaattgttg 421 gcctcctgct gaccacagct atggcagcgg aggtcactag acgtgggagt gcatactaca 481 tgtacttgga cagaaacgat gctggggagg ccatatcttt tccaaccaca ttggggatga 541 ataagtgtta tatacagatc atggatcttg gacacatgtg tgatgccacc atgagctatg 601 aatgccctat gctggatgag ggggtggaac cagatgacgt cgattgttgg tgcaacacga 661 cgtcaacttg ggttgtgtac ggaacctgcc atcacaaaaa aggtgaagca cggagatcta 721 gaagagctgt gacgctcccc tcccattcca ctaggaagct gcaaacgcgg tcgcaaacct 781 ggttggaatc aagagaatac acaaagcact tgattagagt cgaaaattgg atattcagga 841 accctggctt cgcgttagca gcagctgcca tcgcttggct tttgggaagc tcaacgagcc 901 aaaaagtcat atacttggtc atgatactgc tgattgcccc ggcatacagc atcaggtgca 961 taggagtcag caatagggac tttgtggaag gtatgtcagg tgggacttgg gttgatgttg 1021 tcttggaaca tggaggttgt gtcaccgtaa tggcacagga caaaccgact gtcgacatag 1081 agctggttac aacaacagtc agcaacatgg cggaggtaag atcctactgc tatgaggcat 1141 caatatcaga catggcttcg gacagccgct gcccaacaca aggtgaagcc taccttgaca 1201 agcaatcaga cactcaatat gtctgcaaaa gaacgttagt ggacagaggc tggggaaatg 1261 gatgtggact ttttggcaaa gggagcctgg tgacatgcgc taagtttgca tgctccaaga 1321 aaatgaccgg gaagagcatc cagccagaga atctggagta ccggataatg ctgtcagttc 1381 atggctccca gcacagtggg atgatcgtta atgacacagg acatgaaact gatgagaata 1441 gagcgaaggt tgagataacg cccaattcac caagagccga agccaccctg gggggttttg 1501 gaagcctagg acttgattgt gaaccgagga caggccttga cttctcagat ttgtattact 1561 tgactatgaa taacaagcac tggttggttc acaaggagtg gttccacgac attccattac 1621 cttggcacgc tggggcagac accggaactc cacactggaa caacaaagaa gcactggtag 1681 agttcaagga cgcacatgcc aaaaggcaaa ctgtcgtggt tctagggagt caagaaggag 1741 cagttcacac ggcccttgct ggagctctgg aggctgagat ggatggtgca aagggaaggc 1801 tgtcctctgg ccacttgaaa tgtcgcctga aaatggataa acttagattg aagggcgtgt 1861 catactcctt gtgtaccgca gcgttcacat tcaccaagat cccggctgaa acactgcacg 1921 ggacagtcac agtggaggta cagtacgcag ggacagatgg accttgcaag gttccagctc 1981 agatggcggt ggacatgcaa actctgaccc cagttgggag gttgataacc gccaaccccg 2041 taatcactga aagcactgag aactctaaga tgatgctgga acttgatcca ccatttgggg 2101 actcttacat tgtcatagga gtcggggaga agaagatcac ccaccactgg cacaggagtg 2161 gcagcaccat tggaaaagca tttgaagcca ctgtgagagg tgccaagaga atggcagtct 2221 tgggagacac agcctgggac tttggatcag ttggaggcgc tctcaactca ttgggcaagg 2281 gcatccatca aatttttgga gcagctttca aatcattgtt tggaggaatg tcctggttct 2341 cacaaatcct cattggaacg ttgctgatgt ggttgggtct aaacacaaag aatggatcta 2401 tttccctcat gtgcttggcc ttagggggag tgctgatctt cttatccaca gccgtctctg 2461 ctgatgtggg gtgctcggtg gacttctcaa agaaggagac gagatgcggt acaggggtgt 2521 tcgtctataa cgacgttgaa gcctggaggg acaggtacaa gtaccatcct gactcccccc 2581 gtagattggc agcagcagtc aagcaagcct gggaagatgg tatctgcggg atctcctctg 2641 tttcaagaat ggaaaacatc atgtggagat cagtagaagg ggagctcaat gcaatcctgg 2701 aagagaatgg agttcaactg acggtcgttg tgggatctgt aaaaaacccc atgtggagag 2761 gtccacagag attgcccgtg cctgtgaacg agctgcccca cggctggaag gcttggggga 2821 aatcgtactt cgttagagca gcaaagacaa ataacagctt tgtcgtggat ggtgacacac 2881 tgaaggaatg cccactcaaa catagagcat ggaacagctt tcttgtggag gatcatgggt 2941 tcggggtatt ccacactagt gtctggctca aggttagaga agattattca ttagagtgtg 3001 atccagccgt tattggaaca gctgttaagg gaaaggaggc tgtacacagt gatctaggct 3061 actggattga gagtgagaag aatgacacat ggaggctgaa gagggcccat ctgatcgaga 3121 tgaaaacatg tgaatggcca aagtcccaca cattgtggac agatggaata gaagagagtg 3181 atctgatcat acccaagtct ttagctgggc cactcagcca tcacaatacc agagagggct 3241 acaggaccca aatgaaaggg ccatggcaca gtgaagagct tgaaattcgg tttgaggaat 3301 gcccaggcac taaggtccac gtggaggaaa catgtggaac aagaggacca tctctgagat 3361 caaccactgc aagcggaagg gtgatcgagg aatggtgctg cagggagtgc acaatgcccc 3421 cactgtcgtt ccgggctaaa gatggctgtt ggtatggaat ggagataagg cccaggaaag 3481 aaccagaaag caacttagta aggtcagtgg tgactgcagg atcaactgat cacatggatc 3541 acttctccct tggagtgctt gtgattctgc tcatggtgca ggaagggctg aagaagagaa 3601 tgaccacaaa gatcatcata agcacatcaa tggcagtgct ggtagctatg atcctgggag 3661 gattttcaat gagtgacctg gctaagcttg caatcttgat gggtgccacc ttcgcggaaa 3721 tgaacactgg aggagatgta gctcatctgg cgctgatagc ggcattcaaa gtcagaccag 3781 cgttgctggt atctttcatc ttcagagcta attggacacc ccgtgaaagc atgctgctgg 3841 ccttggcctc gtgtcttttg caaactgcga tctccgcctt ggaaggcgac ctgatggttc 3901 tcatcaatgg ttttgctttg gcctggttgg caatacgagc gatggttgtt ccacgcactg 3961 ataacatcac cttggcaatc ctggctgctc tgacaccact ggcccggggc acactgcttg 4021 tggcgtggag agcaggcctt gctacttgcg gggggtttat gctcctctct ctgaagggaa 4081 aaggcagtgt gaagaagaac ttaccatttg tcatggccct gggactaacc gctgtgagac 4141 tggtcgaccc catcaacgtg gtgggactgc tgttgctcac aaggagtggg aagcggagct 4201 ggccccctag cgaagtactc acagctgttg gcctgatatg cgcattggct ggagggttcg 4261 ccaaggcaga tatagagatg gctgggccca tggccgcggt cggtctgcta attgtcagtt 4321 acgtggtctc aggaaagagt gtggacatgt acattgaaag agcaggtgac atcacatggg 4381 aaaaagatgc ggaagtcact ggaaacagtc cccggctcga tgtggcgcta gatgagagtg 4441 gtgatttctc cctggtggag gatgacggtc cccccatgag agagatcata ctcaaggtgg 4501 tcctgatgac catctgtggc atgaacccaa tagccatacc ctttgcagct ggagcgtggt 4561 acgtatacgt gaagactgga aaaaggagtg gtgctctatg ggatgtgcct gctcccaagg 4621 aagtaaaaaa gggggagacc acagatggag tgtacagagt aatgactcgt agactgctag 4681 gttcaacaca agttggagtg ggagttatgc aagagggggt ctttcacact atgtggcacg 4741 tcacaaaagg atccgcgctg agaagcggtg aagggagact tgatccatac tggggagatg 4801 tcaagcagga tctggtgtca tactgtggtc catggaagct agatgccgcc tgggacgggc 4861 acagcgaggt gcagctcttg gccgtgcccc ccggagagag agcgaggaac atccagactc 4921 tgcccggaat atttaagaca aaggatgggg acattggagc ggttgcgctg gattacccag 4981 caggaacttc aggatctcca atcctagaca agtgtgggag agtgatagga ctttatggca 5041 atggggtcgt gatcaaaaat gggagttatg ttagtgccat cacccaaggg aggagggagg 5101 aagagactcc tgttgagtgc ttcgagcctt cgatgctgaa gaagaagcag ctaactgtct 5161 tagacttgca ccctggagct gggaaaacca ggagagttct tcctgaaata gtccgtgaag 5221 ctataaaaac aagactccgt actgtgatct tagctccaac cagggttgtc gctgctgaaa 5281 tggaggaagc ccttagaggg cttccagtgc gttatatgac aacagcagtc aatgtcaccc 5341 attctggaac agaaatcgtc gacttaatgt gccatgccac cttcacttca cgtctactac 5401 agccaatcag agtccccaac tataatctgt atattatgga tgaggcccac ttcacagatc 5461 cctcaagtat agcagcaaga ggatacattt caacaagggt tgagatgggc gaggcggctg 5521 ccatcttcat gaccgccacg ccaccaggaa cccgtgacgc atttccggac tccaactcac 5581 caattatgga caccgaagtg gaagtcccgg agagagcctg gagctcaggc tttgattggg 5641 tgacggatca ttctggaaaa acagtttggt ttgttccaag cgtgaggaac ggcaatgaga 5701 tcgcagcttg tctgacaaag gctggaaaac gggtcataca gctcagcaga aagacttttg 5761 agacagagtt ccagaaaaca aaacatcaag agtgggactt tgtcgtgaca accgacattt 5821 cagagatggg cgccaacttt aaagctgacc gtgtcataga ttccaggaga tgcctaaagc 5881 cggtcatact tgatggcgag agagtcattc tggctggacc catgcctgtc acacatgcca 5941 gcgctgccca gaggaggggg cgcataggca ggaatcccaa caaacctgga gatgagtatc 6001 tgtatggagg tgggtgcgca gagactgacg aagaccatgc acactggctt gaagcaagaa 6061 tgctccttga caatatttac ctccaagatg gcctcatagc ctcgctctat cgacctgagg 6121 ctgacaaagt agcagccatt gagggagagt tcaagcttag gacggagcaa aggaagacct 6181 ttgtggaact catgaaaaga ggagatcttc ctgtttggct ggcctatcag gttgcatctg 6241 ccggaataac ttacacagat agaagatggt gctttgatgg cacgaccaac aacaccataa 6301 tggaagacag tgtgccggca gaggtgtgga ccagacacgg agagaaaaga gtgctcaaac 6361 cgaggtggat ggacgccaga gtttgttcag atcatgcggc cctgaagtca ttcaaggagt 6421 ttgccgctgg gaaaagagga gcggcttttg gagtgatgga agccctggga acactgccag 6481 gacacatgac agagagattc caggaagcca ttgacaacct cgctgtgctc atgcgggcag 6541 agactggaag caggccttac aaagccgcgg cggcccaatt gccggagacc ctagagacca 6601 ttatgctttt ggggttgctg ggaacagtct cgctgggaat ctttttcgtc ttgatgagga 6661 acaagggcat agggaagatg ggctttggaa tggtgactct tggggccagc gcatggctca 6721 tgtggctctc ggaaattgag ccagccagaa ttgcatgtgt cctcattgtt gtgttcctat 6781 tgctggtggt gctcatacct gagccagaaa agcaaagatc tccccaggac aaccaaatgg 6841 caatcatcat catggtagca gtaggtcttc tgggcttgat caccgccaat gaactcggat 6901 ggttggagag aacaaagagt gacctaagcc atctaatggg aaggagagag gagggagcaa 6961 ccataggatt ctcaatggac attgacctgc ggccagcctc agcttgggcc atctatgctg 7021 ccttgacaac tttcattacc ccagccgtcc aacatgcagt gaccacttca tacaacaact 7081 actccttaat ggcgatggcc acgcaagctg gagtgttgtt tggtatgggc aaagggatgc 7141 cattctacgc atgggacttt ggagtcccgc tgctaatgat aggttgctac tcacaattaa 7201 cacccctgac cctaatagtg gccatcattt tgctcgtggc gcactacatg tacttgatcc 7261 cagggctgca ggcagcagct gcgcgtgctg cccagaagag aacggcagct ggcatcatga 7321 agaaccctgt tgtggatgga atagtggtga ctgacattga cacaatgaca attgaccccc 7381 aagtggagaa aaagatggga caggtgctac tcatagcagt agccgtctcc agcgccatac 7441 tgtcgcggac cgcctggggg tggggggagg ctggggccct gatcacagcc gcaacttcca 7501 ctttgtggga aggctctccg aacaagtact ggaactcctc tacagccact tcactgtgta 7561 acatttttag ggggagttac ttggctggag cttctctaat ctacacagta acaagaaacg 7621 ctggcttggt caagagacgt gggggtggaa caggagagac cctgggagag aaatggaagg 7681 cccgcttgaa ccagatgtcg gccctggagt tctactccta caaaaagtca ggcatcaccg 7741 aggtgtgcag agaagaggcc cgccgcgccc tcaaggacgg tgtggcaacg ggaggccatg 7801 ctgtgtcccg aggaagtgca aagctgagat ggttggtgga gcggggatac ctgcagccct 7861 atggaaaggt cattgatctt ggatgtggca gagggggctg gagttactac gccgccacca 7921 tccgcaaagt tcaagaagtg aaaggataca caaaaggagg ccctggtcat gaagaacctg 7981 tgttggtgca aagctatggg tggaacatag tccgtctcaa gagtggggtg gacgtctttc 8041 atatggcggc tgagccgtgt gacacgttgc tgtgtgacat aggtgagtca tcatctagtc 8101 ctgaagtgga agaagcacgg acgctcagag tcctctccat ggtgggggat tggcttgaaa 8161 aaagaccagg agccttttgt ataaaagtgt tgtgcccata caccagcact atgatggaaa 8221 ccttggagcg gctgcagcgt aggtatgggg gaggactggt cagagtgcca ctctcccgca 8281 actctacaca tgagatgtac tgggtctctg gagcgaaaag caacaccata aaaagtgtgt 8341 ccaccacgag ccagctcctc ttggggcgca tggacgggcc taggaggcca gtgaaatatg 8401 aggaggatgt gaatctcggc tctggcacgc gggctgtggt aagctgcgct gaagctccca 8461 acatgaagat cattggtaac cgcattgaaa ggatccgcag tgagcacgcg gaaacgtggt 8521 tctttgacga gaaccaccca tataggacat gggcttacca tggaagctat gaggccccta 8581 cacaagggtc agcatcctct ctagtaaacg gggttgtcag gctcctgtca aaaccctggg 8641 atgtggtgac tggagtcaca ggaatagcca tgaccgacac cacaccgtat ggtcagcaaa 8701 gagttttcaa ggaaaaagtg gacactaggg tgccagaccc ccaagaaggc actcgtcagg 8761 ttatgagcat ggtctcttcc tggttgtgga aagagctagg caaacacaaa cggccacgag 8821 tctgcaccaa agaagagttc atcaacaagg ttcgtagcaa tgcagcatta ggggcaatat 8881 ttgaagagga aaaagagtgg aagactgcag tggaagctgt gaacgatcca aggttctggg 8941 ctctagtgga caaggaaaga gagcaccacc tgagaggaga gtgccagagt tgtgtgtaca 9001 acatgatggg aaaaagagaa aagaaacaag gggaatttgg aaaggccaag ggcagccgcg 9061 ccatctggta tatgtggcta ggggctagat ttctagagtt cgaagccctt ggattcttga 9121 acgaggatca ctggatgggg agagagaact caggaggtgg tgttgaaggg ctgggattac 9181 aaagactcgg atatgtccta gaagagatga gtcgcatacc aggaggaagg atgtatgcag 9241 atgacactgc tggctgggat acccgcatca gcaggtttga tctagagaat gaagctctaa 9301 tcaccaacca aatggagaaa gggcacaggg ccttggcatt ggccataatc aagtacacat 9361 accaaaataa agtggtaaag gtccttagac cagctgaaaa agggaaaaca gttatggaca 9421 ttatttcgag acaagaccaa agggggagcg gacaagttgt cacttacgct cttaacacat 9481 ttaccaacct agtggtgcaa ctcattcgga atatggaggc tgaggaagtt ctagagatgc 9541 aagacttgtg gctgctgcgg aggtcagaga aagtgaccaa ctggttgcag agcaacggat 9601 gggataggct caaacgaatg gcagtcagtg gagatgattg cgttgtgaag ccaattgatg 9661 ataggtttgc acatgccctc aggttcttga atgatatggg aaaagttagg aaggacacac 9721 aagagtggaa accctcaact ggatgggaca actgggaaga agttccgttt tgctcccacc 9781 acttcaacaa gctccatctc aaggacggga ggtccattgt ggttccctgc cgccaccaag 9841 atgaactgat tggccgggcc cgcgtctctc caggggcggg atggagcatc cgggagactg 9901 cttgcctagc aaaatcatat gcgcaaatgt ggcagctcct ttatttccac agaagggacc 9961 tccgactgat ggccaatgcc atttgttcat ctgtgccagt tgactgggtt ccaactggga 10021 gaactacctg gtcaatccat ggaaagggag aatggatgac cattgaagac atgcttgtgg 10081 tgtggaacag agtgtggatt gaggagaacg accacatgga agacaagacc ccagttacga 10141 aatggacaga cattccctat ttgggaaaaa gggaagactt gtggtgtgga tctctcatag 10201 ggcacagacc gcgcaccacc tgggctgaga acattaaaaa cacagtcaac atggtgcgca 10261 ggatcatagg tgaggaagaa aagtacatgg actacctatc cacccaagtt cgttacttgg 10321 gtgaagaagg gtctacacct ggagtgctgt aagcaccaat cttaatgttg tcaggcctgc 10381 tagtcagcca cagcttgggg aaagctgtgc agcctgtgac ccccccagga gaagctggga 10441 aaccaagcct atagtcaggc cgagaacgcc atggcacgga agaagccatg ctgcctgtga 10501 gcccctcaga ggacactgag tcaaaaaacc ccacgcgctt ggaggcgcag gatgggaaaa 10561 gaaggtggcg accttcccca cccttcaatc tggggcctga actgga

LOCUS KX922708 10606 bp RNA linear VRL 05-OCT-2016 DEFINITION Zika virus isolate ZIKV/Aedes_aegypti/USA/2016/FL04M polyprotein gene, complete cds. ACCESSION KX922708 VERSION KX922708.1 GI:1071930520 DBLINK BioProject: PRJNA342539 BioSample: SAMN05853067 KEYWORDS . SOURCE Zika virus ORGANISM Zika virus Viruses; ssRNA viruses; ssRNA positive-strand viruses, no DNA stage; Flaviviridae; Flavivirus. REFERENCE 1 (bases 1 to 10606) AUTHORS Grubaugh,N., Paul,L., Porcelli,M., Vasquez,C., Gangavarupu,K., Oliveira,G., Robles-Sikisaka,R., Michael,S., Isern,S. and Andersen,K. TITLE Zika virus sequences from Florida, USA, 2016 JOURNAL Unpublished REFERENCE 2 (bases 1 to 10606) AUTHORS Grubaugh,N., Paul,L., Porcelli,M., Vasquez,C., Gangavarupu,K., Oliveira,G., Robles-Sikisaka,R., Michael,S., Isern,S. and Andersen,K. TITLE Direct Submission JOURNAL Submitted (29-SEP-2016) Department of Immunology and Microbial Science, The Scripps Research Institute, 10550 North Torrey Pines Road, IMM-210, La Jolla, CA 92037, USA COMMENT ##Assembly-Data-START## Assembly Method :: NovoAlign v. V3.04 Sequencing Technology :: Illumina ##Assembly-Data-END## FEATURES Location/Qualifiers source 1..10606 /organism="Zika virus" /mol_type="genomic RNA" /isolate="ZIKV/Aedes_aegypti/USA/2016/FL04M" /isolation_source="pool of 50 adult mosquitoes" /host="Aedes aegypti" /db_xref="taxon:64320" /country="USA: Miami, Florida" /collection_date="04-Sep-2016"

1. Zika virus isolate ZIKV/Homo_sapiens/USA/2016/FL021U polyprotein gene, complete cds 10,365 bp linear RNA Accession: KX922703.1 GI: 1071930510 GenBankFASTAGraphics Select item 10719305122. Zika virus isolate ZIKV/Homo_sapiens/USA/2016/FL030U polyprotein gene, complete cds 10,609 bp linear RNA Accession: KX922704.1 GI: 1071930512 GenBankFASTAGraphics Select item 10719305143. Zika virus isolate ZIKV/Homo_sapiens/USA/2016/FL032U polyprotein gene, complete cds 10,609 bp linear RNA Accession: KX922705.1 GI: 1071930514 GenBankFASTAGraphics Select item 10719305164. Zika virus isolate ZIKV/Homo_sapiens/USA/2016/FL038U polyprotein gene, complete cds 10,610 bp linear RNA Accession: KX922706.1 GI: 1071930516 GenBankFASTAGraphics Select item 10719305185. Zika virus isolate ZIKV/Homo_sapiens/USA/2016/FL039U polyprotein gene, complete cds 10,609 bp linear RNA Accession: KX922707.1 GI: 1071930518 GenBankFASTAGraphics Select item 10719305206. Zika virus isolate ZIKV/Aedes_aegypti/USA/2016/FL04M polyprotein gene, complete cds 10,606 bp linear RNA Accession: KX922708.1 GI: 1071930520 GenBankFASTAGraphics

1. Zika virus isolate ZIKV/Homo_sapiens/USA/2016/FL021U polyprotein gene, complete cds 10,365 bp linear RNA Accession: KX922703.1 GI: 1071930510 GenBankFASTAGraphics Select item 10719305122. Zika virus isolate ZIKV/Homo_sapiens/USA/2016/FL030U polyprotein gene, complete cds 10,609 bp linear RNA Accession: KX922704.1 GI: 1071930512 GenBankFASTAGraphics Select item 10719305143. Zika virus isolate ZIKV/Homo_sapiens/USA/2016/FL032U polyprotein gene, complete cds 10,609 bp linear RNA Accession: KX922705.1 GI: 1071930514 GenBankFASTAGraphics Select item 10719305164. Zika virus isolate ZIKV/Homo_sapiens/USA/2016/FL038U polyprotein gene, complete cds 10,610 bp linear RNA Accession: KX922706.1 GI: 1071930516 GenBankFASTAGraphics Select item 10719305185. Zika virus isolate ZIKV/Homo_sapiens/USA/2016/FL039U polyprotein gene, complete cds 10,609 bp linear RNA Accession: KX922707.1 GI: 1071930518 GenBankFASTAGraphics Select item 10719305206. Zika virus isolate ZIKV/Aedes_aegypti/USA/2016/FL04M polyprotein gene, complete cds 10,606 bp linear RNA Accession: KX922708.1 GI: 1071930520 GenBankFASTAGraphics

1. Zika virus isolate ZIKV/Homo_sapiens/USA/2016/FL021U polyprotein gene, complete cds 10,365 bp linear RNA Accession: KX922703.1 GI: 1071930510 GenBankFASTAGraphics Select item 10719305122. Zika virus isolate ZIKV/Homo_sapiens/USA/2016/FL030U polyprotein gene, complete cds 10,609 bp linear RNA Accession: KX922704.1 GI: 1071930512 GenBankFASTAGraphics Select item 10719305143. Zika virus isolate ZIKV/Homo_sapiens/USA/2016/FL032U polyprotein gene, complete cds 10,609 bp linear RNA Accession: KX922705.1 GI: 1071930514 GenBankFASTAGraphics Select item 10719305164. Zika virus isolate ZIKV/Homo_sapiens/USA/2016/FL038U polyprotein gene, complete cds 10,610 bp linear RNA Accession: KX922706.1 GI: 1071930516 GenBankFASTAGraphics Select item 10719305185. Zika virus isolate ZIKV/Homo_sapiens/USA/2016/FL039U polyprotein gene, complete cds 10,609 bp linear RNA Accession: KX922707.1 GI: 1071930518 GenBankFASTAGraphics Select item 10719305206. Zika virus isolate ZIKV/Aedes_aegypti/USA/2016/FL04M polyprotein gene, complete cds 10,606 bp linear RNA Accession: KX922708.1 GI: 1071930520 GenBankFASTAGraphics

1. Zika virus isolate ZIKV/Homo_sapiens/USA/2016/FL021U polyprotein gene, complete cds 10,365 bp linear RNA Accession: KX922703.1 GI: 1071930510 GenBankFASTAGraphics Select item 10719305122. Zika virus isolate ZIKV/Homo_sapiens/USA/2016/FL030U polyprotein gene, complete cds 10,609 bp linear RNA Accession: KX922704.1 GI: 1071930512 GenBankFASTAGraphics Select item 10719305143. Zika virus isolate ZIKV/Homo_sapiens/USA/2016/FL032U polyprotein gene, complete cds 10,609 bp linear RNA Accession: KX922705.1 GI: 1071930514 GenBankFASTAGraphics Select item 10719305164. Zika virus isolate ZIKV/Homo_sapiens/USA/2016/FL038U polyprotein gene, complete cds 10,610 bp linear RNA Accession: KX922706.1 GI: 1071930516 GenBankFASTAGraphics Select item 10719305185. Zika virus isolate ZIKV/Homo_sapiens/USA/2016/FL039U polyprotein gene, complete cds 10,609 bp linear RNA Accession: KX922707.1 GI: 1071930518 GenBankFASTAGraphics Select item 10719305206. Zika virus isolate ZIKV/Aedes_aegypti/USA/2016/FL04M polyprotein gene, complete cds 10,606 bp linear RNA Accession: KX922708.1 GI: 1071930520 GenBankFASTAGraphics

Sequences producing significant alignments: Select:AllNone Selected:0 AlignmentsDownloadGenBankGraphicsDistance tree of resultsShow/hide columns of the table presenting sequences producing significant alignments Sequences producing significant alignments: Select for downloading or viewing reports Description Max score Total score Query cover E value Ident Accession Select seq gb|KU853013.1| Zika virus isolate Dominican Republic/2016/PD2, complete genome 18465 18465 100% 0.0 99% KU853013.1 Select seq gb|KU853012.1| Zika virus isolate Dominican Republic/2016/PD1, complete genome 18465 18465 100% 0.0 99% KU853012.1 Select seq gb|KX842449.1| Zika virus isolate ZIKV/Human/USA/2016/ZF10.UR-010 polyprotein gene, complete cds 18429 18429 100% 0.0 99% KX842449.1 Select seq gb|KX838905.1| Zika virus isolate ZIKV/Aedes_aegypti/USA/2016/ZM2-7719 polyprotein gene, complete cds 18426 18426 100% 0.0 99% KX838905.1 Select seq gb|KX838904.1| Zika virus isolate ZIKV/Aedes_aegypti/USA/2016/ZM1-7501 polyprotein gene, complete cds 18420 18420 100% 0.0 99% KX838904.1 Select seq gb|KX832731.1| Zika virus isolate ZIKV/Human/USA/2016/ZL2.SA-Hu0015 polyprotein gene, complete cds 18420 18420 100% 0.0 99% KX832731.1 Select seq gb|KX673530.1| Zika virus isolate PHE_semen_Guadeloupe, complete genome 18417 18417 100% 0.0 99% KX673530.1 Select seq gb|KX838906.1| Zika virus isolate ZIKV/Aedes_aegypti/USA/2016/ZM3-7729 polyprotein gene, complete cds 18408 18408 100% 0.0 99% KX838906.1 Select seq gb|KX447510.1| Zika virus isolate 1_0049_PF polyprotein gene, complete cds 18357 18357 100% 0.0 99% KX447510.1 Select seq gb|KX280026.1| Zika virus isolate Paraiba_01, complete genome 18354 18354 100% 0.0 99% KX280026.1 Select seq gb|KX447512.1| Zika virus isolate 1_0181_PF polyprotein gene, complete cds 18348 18348 100% 0.0 99% KX447512.1 Select seq gb|KX369547.1| Zika virus strain PF13/251013-18, complete genome 18348 18348 100% 0.0 99% KX369547.1 Select seq gb|KU509998.3| Zika virus strain Haiti/1225/2014, complete genome 18348 18348 100% 0.0 99% KU509998.3 Select seq gb|KJ776791.2| Zika virus strain H/PF/2013, complete genome 18345 18345 100% 0.0 99% KJ776791.2 Select seq gb|KX447509.1| Zika virus isolate 1_0087_PF polyprotein gene, complete cds 18345 18345 100% 0.0 99% KX447509.1 Select seq gb|KU991811.1| Zika virus isolate Brazil/2016/INMI1 polyprotein gene, complete cds 18345 18345 100% 0.0 99% KU991811.1 Select seq gb|KU729217.2| Zika virus isolate BeH823339 polyprotein gene, complete cds 18345 18345 100% 0.0 99% KU729217.2 Select seq gb|KX447513.1| Zika virus isolate 1_0134_PF polyprotein gene, complete cds 18339 18339 100% 0.0 99% KX447513.1 Select seq gb|KX811222.1| Zika virus isolate Brazil_2015_MG, complete genome 18336 18336 100% 0.0 99% KX811222.1 Select seq gb|KX197205.1| Zika virus isolate 9, complete genome 18336 18336 100% 0.0 99% KX197205.1 Select seq gb|KX447515.1| Zika virus isolate 1_0030_PF polyprotein gene, complete cds 18336 18336 100% 0.0 99% KX447515.1 Select seq gb|KX447511.1| Zika virus isolate 1_0015_PF polyprotein gene, complete cds 18336 18336 100% 0.0 99% KX447511.1 Select seq gb|KU321639.1| Zika virus strain ZikaSPH2015, complete genome 18336 18336 100% 0.0 99% KU321639.1 Select seq gb|KX879604.1| Zika virus isolate SN089, complete genome 18330 18330 100% 0.0 99% KX879604.1 Select seq gb|KX447514.1| Zika virus isolate 1_0035_PF polyprotein gene, complete cds 18330 18330 100% 0.0 99% KX447514.1 Select seq gb|KX051563.1| Zika virus isolate Haiti/1/2016, complete genome 18330 18330 100% 0.0 99% KX051563.1 Select seq gb|KX447516.1| Zika virus isolate 1_0111_PF polyprotein gene, complete cds 18327 18327 100% 0.0 99% KX447516.1 Select seq gb|KU729218.1| Zika virus isolate BeH828305 polyprotein gene, complete cds 18327 18327 100% 0.0 99% KU729218.1 Select seq gb|KU707826.1| Zika virus isolate SSABR1, complete genome 18327 18327 100% 0.0 99% KU707826.1 Select seq gb|KU527068.1| Zika virus strain Natal RGN, complete genome 18327 18327 100% 0.0 99% KU527068.1 Select seq gb|KU365779.1| Zika virus strain BeH819966 polyprotein gene, complete cds 18327 18327 100% 0.0 99% KU365779.1 Select seq gb|KX879603.1| Zika virus isolate SN062, complete genome 18321 18321 100% 0.0 99% KX879603.1 Select seq gb|KX262887.1| Zika virus isolate 103451, complete genome 18321 18321 100% 0.0 99% KX262887.1 Select seq gb|KX197192.1| Zika virus isolate ZIKV/H.sapiens/Brazil/PE243/2015, complete genome 18321 18321 100% 0.0 99% KX197192.1 Select seq gb|KU926310.1| Zika virus isolate Rio-S1, complete genome 18321 18321 100% 0.0 99% KU926310.1 Select seq gb|KU926309.1| Zika virus isolate Rio-U1, complete genome 18321 18321 100% 0.0 99% KU926309.1 Select seq gb|KU501217.1| Zika virus strain 8375 polyprotein gene, complete cds 18321 18321 100% 0.0 99% KU501217.1 Select seq gb|KU940228.1| Zika virus isolate Bahia07, partial genome 18318 18318 100% 0.0 99% KU940228.1 Select seq gb|KU501216.1| Zika virus strain 103344 polyprotein gene, complete cds 18318 18318 100% 0.0 99% KU501216.1 Select seq gb|KX694534.1| Zika virus strain ZIKV/Homo sapiens/HND/R103451/2015, complete genome 18312 18312 100% 0.0 99% KX694534.1 Select seq gb|KX198135.1| Zika virus strain ZIKV/Homo sapiens/PAN/BEI-259634_V4/2016, complete genome 18312 18312 100% 0.0 99% KX198135.1 Select seq gb|KU365780.1| Zika virus strain BeH815744 polyprotein gene, complete cds 18312 18312 100% 0.0 99% KU365780.1 Select seq gb|KU647676.1| Zika virus strain MRS_OPY_Martinique_PaRi_2015 polyprotein gene, complete cds 18309 18309 100% 0.0 99% KU647676.1 Select seq gb|KU365777.1| Zika virus strain BeH818995 polyprotein gene, complete cds 18309 18309 100% 0.0 99% KU365777.1 Select seq gb|KX447517.1| Zika virus isolate 1_0038_PF polyprotein gene, complete cds 18303 18303 100% 0.0 99% KX447517.1 Select seq gb|KU758877.1| Zika virus isolate 17271 polyprotein gene, complete cds 18303 18303 100% 0.0 99% KU758877.1 Select seq gb|KX247646.1| Zika virus isolate Zika virus/Homo sapiens/COL/UF-1/2016, complete genome 18303 18303 100% 0.0 99% KX247646.1 Select seq gb|KX156776.1| Zika virus strain ZIKV/Homo sapiens/PAN/CDC-259364_V1-V2/2015, complete genome 18303 18303 100% 0.0 99% KX156776.1 Select seq gb|KX520666.1| Zika virus isolate HS-2015-BA-01 polyprotein gene, complete cds 18300 18300 100% 0.0 99% KX520666.1 Select seq gb|KX156774.1| Zika virus strain ZIKV/Homo sapiens/PAN/CDC-259359_V1-V3/2015, complete genome 18300 18300 100% 0.0 99% KX156774.1 Select seq gb|KU497555.1| Zika virus isolate Brazil-ZKV2015, complete genome 18300 18300 99% 0.0 99% KU497555.1 Select seq gb|KU820897.5| Zika virus isolate FLR polyprotein gene, complete cds 18294 18294 100% 0.0 99% KU820897.5 Select seq gb|KX247632.1| Zika virus isolate MEX_I_7 polyprotein gene, complete cds 18294 18294 100% 0.0 99% KX247632.1 Select seq gb|KX156775.1| Zika virus strain ZIKV/Homo sapiens/PAN/CDC-259249_V1-V3/2015, complete genome 18294 18294 100% 0.0 99% KX156775.1 Select seq gb|KX087102.1| Zika virus strain ZIKV/Homo sapiens/COL/FLR/2015, complete genome 18294 18294 100% 0.0 99% KX087102.1 Select seq gb|KU365778.1| Zika virus strain BeH819015 polyprotein gene, complete cds 18294 18294 100% 0.0 99% KU365778.1 Select seq gb|KU312312.1| Zika virus isolate Z1106033 polyprotein gene, complete cds 18294 18294 100% 0.0 99% KU312312.1 Select seq gb|KU922960.1| Zika virus isolate MEX/InDRE/Sm/2016, complete genome 18291 18291 100% 0.0 99% KU922960.1 Select seq gb|KX856011.1| Zika virus strain ZIKV/Aedes sp./MEX_I-44/2016, complete genome 18285 18285 100% 0.0 99% KX856011.1 Select seq gb|KX806557.1| Zika virus isolate TS17-2016, complete genome 18285 18285 100% 0.0 99% KX806557.1 Select seq gb|KX548902.1| Zika virus isolate ZIKV/COL/FCC00093/2015 polyprotein gene, complete cds 18285 18285 100% 0.0 99% KX548902.1 Select seq gb|KX446951.1| Zika virus strain ZIKV/Aedes.sp/MEX/MEX_I-7/2016, complete genome 18285 18285 100% 0.0 99% KX446951.1 Select seq gb|KU937936.1| Zika virus isolate ZIKVNL00013 polyprotein gene, complete cds 18285 18285 100% 0.0 99% KU937936.1 Select seq gb|KU922923.1| Zika virus isolate MEX/InDRE/Lm/2016, complete genome 18285 18285 100% 0.0 99% KU922923.1 Select seq gb|KU501215.1| Zika virus strain PRVABC59, complete genome 18285 18285 100% 0.0 99% KU501215.1 Select seq gb|KX601168.1| Zika virus strain ZIKV/Homo Sapiens/PRI/PRVABC59/2015, complete genome 18282 18282 100% 0.0 99% KX601168.1 Select seq gb|KX446950.1| Zika virus strain ZIKV/Aedes.sp/MEX/MEX_2-81/2016, complete genome 18282 18282 100% 0.0 99% KX446950.1 Select seq gb|KX087101.2| Zika virus strain ZIKV/Homo sapiens/PRI/PRVABC59/2015, complete genome 18282 18282 100% 0.0 99% KX087101.2 Select seq gb|KU870645.1| Zika virus isolate FB-GWUH-2016, complete genome 18282 18282 100% 0.0 99% KU870645.1 Select seq gb|KX702400.1| Zika virus strain Zika virus/Homo sapiens/VEN/UF-1/2016, complete genome 18276 18276 100% 0.0 99% KX702400.1 Select seq gb|KX377337.1| Zika virus strain PRVABC-59, complete genome 18276 18276 100% 0.0 99% KX377337.1 Select seq gb|KX766029.1| Zika virus isolate R116265, complete genome 18267 18267 100% 0.0 99% KX766029.1 Select seq gb|KU820898.1| Zika virus isolate GZ01 polyprotein gene, complete cds 18267 18267 100% 0.0 99% KU820898.1 Select seq gb|KX056898.1| Zika virus isolate Zika virus/GZ02/2016 polyprotein gene, complete cds 18264 18264 100% 0.0 99% KX056898.1 Select seq gb|KU955590.1| Zika virus isolate Z16019 polyprotein gene, complete cds 18264 18264 100% 0.0 99% KU955590.1 Select seq gb|KX766028.1| Zika virus isolate R114916, complete genome 18260 18260 100% 0.0 99% KX766028.1 Select seq gb|KU740184.2| Zika virus isolate GD01 polyprotein gene, complete cds 18258 18258 100% 0.0 99% KU740184.2 Select seq gb|KU761564.1| Zika virus isolate GDZ16001 polyprotein gene, complete cds 18258 18258 100% 0.0 99% KU761564.1 Select seq gb|KX117076.1| Zika virus isolate Zhejiang04, complete genome 18254 18254 100% 0.0 99% KX117076.1 Select seq gb|KX185891.1| Zika virus isolate Zika virus/CN/SZ02/2016 polyprotein gene, complete cds 18245 18245 100% 0.0 99% KX185891.1 Select seq gb|KU963796.1| Zika virus isolate SZ-WIV01 polyprotein gene, complete cds 18245 18245 100% 0.0 99% KU963796.1 Select seq gb|KX253996.1| Zika virus isolate ZKC2/2016, complete genome 18240 18240 100% 0.0 99% KX253996.1 Select seq gb|KU955589.1| Zika virus isolate Z16006 polyprotein gene, complete cds 18240 18240 100% 0.0 99% KU955589.1 Select seq gb|KU820899.2| Zika virus isolate ZJ03, complete genome 18240 18240 100% 0.0 99% KU820899.2 Select seq gb|KX266255.1| Zika virus isolate ZIKV_SMGC-1, complete genome 18236 18236 100% 0.0 99% KX266255.1 Select seq gb|KU866423.2| Zika virus isolate Zika virus/SZ01/2016/China polyprotein gene, complete cds 18236 18236 100% 0.0 99% KU866423.2 Select seq gb|KU940224.1| Zika virus isolate Bahia09, partial genome 18222 18222 99% 0.0 99% KU940224.1 Select seq gb|KU744693.1| Zika virus isolate VE_Ganxian, complete genome 18101 18101 100% 0.0 99% KU744693.1 Select seq gb|KX827309.1| Zika virus isolate ZKA-16-291 polyprotein gene, complete cds 18078 18078 100% 0.0 99% KX827309.1 Select seq gb|KX813683.1| Zika virus isolate ZKA-16-097 polyprotein gene, complete cds 18065 18065 100% 0.0 99% KX813683.1 Select seq gb|KU681081.3| Zika virus isolate Zika virus/H.sapiens-tc/THA/2014/SV0127- 14, complete genome 18011 18011 100% 0.0 99% KU681081.3 Select seq gb|KX694532.1| Zika virus strain ZIKV/Homo sapiens/THA/PLCal_ZV/2013, complete genome 17897 17897 100% 0.0 99% KX694532.1 Select seq gb|KU955593.1| Zika virus isolate Zika virus/H.sapiens-tc/KHM/2010/FSS13025, complete genome 17704 17704 100% 0.0 98% KU955593.1 Select seq gb|JN860885.1| Zika virus isolate FSS13025 polyprotein gene, partial cds 17703 17703 99% 0.0 98% JN860885.1 Select seq gb|KF993678.1| Zika virus strain PLCal_ZV from Canada polyprotein gene, partial cds 17667 17667 98% 0.0 99% KF993678.1 Select seq gb|EU545988.1| Zika virus polyprotein gene, complete cds 17558 17558 100% 0.0 98% EU545988.1 Select seq gb|KU681082.3| Zika virus isolate Zika virus/H.sapiens-tc/PHL/2012/CPC-0740, complete genome 17411 17411 100% 0.0 98% KU681082.3 Select seq gb|KX601167.1| Zika virus strain ZIKV/Aedes sp./MYS/P6-740/1966, complete genome 16401 16401 100% 0.0 95% KX601167.1 Select seq gb|HQ234499.1| Zika virus isolate P6-740 polyprotein gene, partial cds 16393 16393 99% 0.0 95% HQ234499.1 Select seq gb|KX694533.1| Zika virus strain ZIKV/Aedes aegypti/MYS/P6-740/1966, complete genome 16392 16392 100% 0.0 95% KX694533.1

LOCUS KX922707 10609 bp RNA linear VRL 05-OCT-2016 DEFINITION Zika virus isolate ZIKV/Homo_sapiens/USA/2016/FL039U polyprotein gene, complete cds. ACCESSION KX922707 VERSION KX922707.1 GI:1071930518 DBLINK BioProject: PRJNA342539 BioSample: SAMN05853066 KEYWORDS . SOURCE Zika virus ORGANISM Zika virus Viruses; ssRNA viruses; ssRNA positive-strand viruses, no DNA stage; Flaviviridae; Flavivirus. REFERENCE 1 (bases 1 to 10609) AUTHORS Grubaugh,N., Tan,A., Gangavarupu,K., Oliveira,G., Robles-Sikisaka,R., Cone,M., Kopp,E., Hogan,K., Cannons,A., Michael,S., Isern,S. and Andersen,K. TITLE Zika virus sequences from Florida, USA, 2016 JOURNAL Unpublished REFERENCE 2 (bases 1 to 10609) AUTHORS Grubaugh,N., Tan,A., Gangavarupu,K., Oliveira,G., Robles-Sikisaka,R., Cone,M., Kopp,E., Hogan,K., Cannons,A., Michael,S., Isern,S. and Andersen,K. TITLE Direct Submission JOURNAL Submitted (29-SEP-2016) Department of Immunology and Microbial Science, The Scripps Research Institute, 10550 North Torrey Pines Road, IMM-210, La Jolla, CA 92037, USA COMMENT ##Assembly-Data-START## Assembly Method :: NovoAlign v. V3.04 Sequencing Technology :: Illumina ##Assembly-Data-END## FEATURES Location/Qualifiers source 1..10609 /organism="Zika virus" /mol_type="genomic RNA" /isolate="ZIKV/Homo_sapiens/USA/2016/FL039U" /isolation_source="urine" /host="Homo sapiens" /db_xref="taxon:64320" /country="USA: Florida" /collection_date="17-Aug-2016" CDS 81..10352 /codon_start=1 /product="polyprotein" /protein_id="AOS90224.1" /db_xref="GI:1071930519" /translation="MKNPKKKSGGFRIVNMLKRGVARVSPFGGLKRLPAGLLLGHGPI RMVLAILAFLRFTAIKPSLGLINRWGSVGKKEAMEIIKKFKKDLAAMLRIINARKEKK RRGADTSVGIVGLLLTTAMAAEVTRRGSAYYMYLDRNDAGEAISFPTTLGMNKCYIQI MDLGHMCDATMSYECPMLDEGVEPDDVDCWCNTTSTWVVYGTCHHKKGEARRSRRAVT LPSHSTRKLQTRSQTWLESREYTKHLIRVENWIFRNPGFALAAAAIAWLLGSSTSQKV IYLVMILLIAPAYSIRCIGVSNRDFVEGMSGGTWVDVVLEHGGCVTVMAQDKPTVDIE LVTTTVSNMAEVRSYCYEASISDMASDSRCPTQGEAYLDKQSDTQYVCKRTLVDRGWG NGCGLFGKGSLVTCAKFACSKKMTGKSIQPENLEYRIMLSVHGSQHSGMIVNDTGHET DENRAKVEITPNSPRAEATLGGFGSLGLDCEPRTGLDFSDLYYLTMNNKHWLVHKEWF HDIPLPWHAGADTGTPHWNNKEALVEFKDAHAKRQTVVVLGSQEGAVHTALAGALEAE MDGAKGRLSSGHLKCRLKMDKLRLKGVSYSLCTAAFTFTKIPAETLHGTVTVEVQYAG TDGPCKVPAQMAVDMQTLTPVGRLITANPVITESTENSKMMLELDPPFGDSYIVIGVG EKKITHHWHRSGSTIGKAFEATVRGAKRMAVLGDTAWDFGSVGGALNSLGKGIHQIFG AAFKSLFGGMSWFSQILIGTLLMWLGLNTKNGSISLMCLALGGVLIFLSTAVSADVGC SVDFSKKETRCGTGVFVYNDVEAWRDRYKYHPDSPRRLAAAVKQAWEDGICGISSVSR MENIMWRSVEGELNAILEENGVQLTVVVGSVKNPMWRGPQRLPVPVNELPHGWKAWGK SYFVRAAKTNNSFVVDGDTLKECPLKHRAWNSFLVEDHGFGVFHTSVWLKVREDYSLE CDPAVIGTAVKGKEAVHSDLGYWIESEKNDTWRLKRAHLIEMKTCEWPKSHTLWTDGI EESDLIIPKSLAGPLSHHNTREGYRTQMKGPWHSEELEIRFEECPGTKVHVEETCGTR GPSLRSTTASGRVIEEWCCRECTMPPLSFRAKDGCWYGMEIRPRKEPESNLVRSVVTA GSTDHMDHFSLGVLVILLMVQEGLKKRMTTKIIISTSMAVLVAMILGGFSMSDLAKLA ILMGATFAEMNTGGDVAHLALIAAFKVRPALLVSFIFRANWTPRESMLLALASCLLQT AISALEGDLMVLINGFALAWLAIRAMVVPRTDNITLAILAALTPLARGTLLVAWRAGL ATCGGFMLLSLKGKGSVKKNLPFVMALGLTAVRLVDPINVVGLLLLTRSGKRSWPPSE VLTAVGLICALAGGFAKADIEMAGPMAAVGLLIVSYVVSGKSVDMYIERAGDITWEKD AEVTGNSPRLDVALDESGDFSLVEDDGPPMREIILKVVLMTICGMNPIAIPFAAGAWY VYVKTGKRSGALWDVPAPKEVKKGETTDGVYRVMTRRLLGSTQVGVGVMQEGVFHTMW HVTKGSALRSGEGRLDPYWGDVKQDLVSYCGPWKLDAAWDGHSEVQLLAVPPGERARN IQTLPGIFKTKDGDIGAVALDYPAGTSGSPILDKCGRVIGLYGNGVVIKNGSYVSAIT QGRREEETPVECFEPSMLKKKQLTVLDLHPGAGKTRRVLPEIVREAIKTRLRTVILAP TRVVAAEMEEALRGLPVRYMTTAVNVTHSGTEIVDLMCHATFTSRLLQPIRVPNYNLY IMDEAHFTDPSSIAARGYISTRVEMGEAAAIFMTATPPGTRDAFPDSNSPIMDTEVEV PERAWSSGFDWVTDHSGKTVWFVPSVRNGNEIAACLTKAGKRVIQLSRKTFETEFQKT KHQEWDFVVTTDISEMGANFKADRVIDSRRCLKPVILDGERVILAGPMPVTHASAAQR RGRIGRNPNKPGDEYLYGGGCAETDEDHAHWLEARMLLDNIYLQDGLIASLYRPEADK VAAIEGEFKLRTEQRKTFVELMKRGDLPVWLAYQVASAGITYTDRRWCFDGTTNNTIM EDSVPAEVWTRHGEKRVLKPRWMDARVCSDHAALKSFKEFAAGKRGAAFGVMEALGTL PGHMTERFQEAIDNLAVLMRAETGSRPYKAAAAQLPETLETIMLLGLLGTVSLGIFFV LMRNKGIGKMGFGMVTLGASAWLMWLSEIEPARIACVLIVVFLLLVVLIPEPEKQRSP QDNQMAIIIMVAVGLLGLITANELGWLERTKSDLSHLMGRREEGATIGFSMDIDLRPA SAWAIYAALTTFITPAVQHAVTTSYNNYSLMAMATQAGVLFGMGKGMPFYAWDFGVPL LMIGCYSQLTPLTLIVAIILLVAHYMYLIPGLQAAAARAAQKRTAAGIMKNPVVDGIV VTDIDTMTIDPQVEKKMGQVLLIAVAVSSAILSRTAWGWGEAGALITAATSTLWEGSP NKYWNSSTATSLCNIFRGSYLAGASLIYTVTRNAGLVKRRGGGTGETLGEKWKARLNQ MSALEFYSYKKSGITEVCREEARRALKDGVATGGHAVSRGSAKLRWLVERGYLQPYGK VIDLGCGRGGWSYYAATIRKVQEVKGYTKGGPGHEEPVLVQSYGWNIVRLKSGVDVFH MAAEPCDTLLCDIGESSSSPEVEEARTLRVLSMVGDWLEKRPGAFCIKVLCPYTSTMM ETLERLQRRYGGGLVRVPLSRNSTHEMYWVSGAKSNTIKSVSTTSQLLLGRMDGPRRP VKYEEDVNLGSGTRAVVSCAEAPNMKIIGNRIERIRSEHAETWFFDENHPYRTWAYHG SYEAPTQGSASSLVNGVVRLLSKPWDVVTGVTGIAMTDTTPYGQQRVFKEKVDTRVPD PQEGTRQVMSMVSSWLWKELGKHKRPRVCTKEEFINKVRSNAALGAIFEEEKEWKTAV EAVNDPRFWALVDKEREHHLRGECQSCVYNMMGKREKKQGEFGKAKGSRAIWYMWLGA RFLEFEALGFLNEDHWMGRENSGGGVEGLGLQRLGYVLEEMSRIPGGRMYADDTAGWD TRISRFDLENEALITNQMEKGHRALALAIIKYTYQNKVVKVLRPAEKGKTVMDIISRQ DQRGSGQVVTYALNTFTNLVVQLIRNMEAEEVLEMQDLWLLRRSEKVTNWLQSNGWDR LKRMAVSGDDCVVKPIDDRFAHALRFLNDMGKVRKDTQEWKPSTGWDNWEEVPFCSHH FNKLHLKDGRSIVVPCRHQDELIGRARVSPGAGWSIRETACLAKSYAQMWQLLYFHRR DLRLMANAICSSVPVDWVPTGRTTWSIHGKGEWMTTEDMLVVWNRVWIEENDHMEDKT PVTKWTDIPYLGKREDLWCGSLIGHRPRTTWAENIKNTVNMVRRIIGEEEKYMDYLST QVRYLGEEGSTPGVL" ORIGIN 1 cgacagttcg agtttgaagc gaaagctagc aacagtatca acaggtttta ttttggattt 61 ggaaacgaga gtttctggtc atgaaaaacc caaaaaagaa atccggagga ttccggattg 121 tcaatatgct aaaacgcgga gtagcccgtg tgagcccctt tgggggcttg aagaggctgc 181 cagccggact tctgctgggt catgggccca tcaggatggt cttggcgatt ctagcctttt 241 tgagattcac ggcaatcaag ccatcactgg gtctcatcaa tagatggggt tcagtgggga 301 aaaaagaggc tatggaaata ataaagaagt tcaagaaaga tctggctgcc atgctgagaa 361 taatcaatgc taggaaggag aagaagagac gaggcgcaga tactagtgtc ggaattgttg 421 gcctcctgct gaccacagct atggcagcgg aggtcactag acgtgggagt gcatactaca 481 tgtacttgga cagaaacgat gctggggagg ccatatcttt tccaaccaca ttggggatga 541 ataagtgtta tatacagatc atggatcttg gacacatgtg tgatgccacc atgagctatg 601 aatgccctat gctggatgag ggggtggaac cagatgacgt cgattgttgg tgcaacacga 661 cgtcaacttg ggttgtgtac ggaacctgcc atcacaaaaa aggtgaagca cggagatcta 721 gaagagctgt gacgctcccc tcccattcca ctaggaagct gcaaacgcgg tcgcaaacct 781 ggttggaatc aagagaatac acaaagcact tgattagagt cgaaaattgg atattcagga 841 accctggctt cgcgttagca gcagctgcca tcgcttggct tttgggaagc tcaacgagcc 901 aaaaagtcat atacttggtc atgatactgc tgattgcccc ggcatacagc atcaggtgca 961 taggagtcag caatagggac tttgtggaag gtatgtcagg tgggacttgg gttgatgttg 1021 tcttggaaca tggaggttgt gtcaccgtaa tggcacagga caaaccgact gtcgacatag 1081 agctggttac aacaacagtc agcaacatgg cggaggtaag atcctactgc tatgaggcat 1141 caatatcaga catggcttcg gacagccgct gcccaacaca aggtgaagcc taccttgaca 1201 agcaatcaga cactcaatat gtctgcaaaa gaacgttagt ggacagaggc tggggaaatg 1261 gatgtggact ttttggcaaa gggagcctgg tgacatgcgc taagtttgca tgctccaaga 1321 aaatgaccgg gaagagcatc cagccagaga atctggagta ccggataatg ctgtcagttc 1381 atggctccca gcacagtggg atgatcgtta atgacacagg acatgaaact gatgagaata 1441 gagcgaaggt tgagataacg cccaattcac caagagccga agccaccctg gggggttttg 1501 gaagcctagg acttgattgt gaaccgagga caggccttga cttttcagat ttgtattact 1561 tgactatgaa taacaagcac tggttggttc acaaggagtg gttccacgac attccattac 1621 cttggcacgc tggggcagac accggaactc cacactggaa caacaaagaa gcactggtag 1681 agttcaagga cgcacatgcc aaaaggcaaa ctgtcgtggt tctagggagt caagaaggag 1741 cagttcacac ggcccttgct ggagctctgg aggctgagat ggatggtgca aagggaaggc 1801 tgtcctctgg ccacttgaaa tgtcgcctga aaatggataa acttagattg aagggcgtgt 1861 catactcctt gtgtaccgca gcgttcacat tcaccaagat cccggctgaa acactgcacg 1921 ggacagtcac agtggaggta cagtacgcag ggacagatgg accttgcaag gttccagctc 1981 agatggcggt ggacatgcaa actctgaccc cagttgggag gttgataacc gccaaccccg 2041 taatcactga aagcactgag aactctaaga tgatgctgga acttgatcca ccatttgggg 2101 actcttacat tgtcatagga gtcggggaga agaagatcac ccaccactgg cacaggagtg 2161 gcagcaccat tggaaaagca tttgaagcca ctgtgagagg tgccaagaga atggcagtct 2221 tgggagacac agcctgggac tttggatcag ttggaggcgc tctcaactca ttgggcaagg 2281 gcatccatca aatttttgga gcagctttca aatcattgtt tggaggaatg tcctggttct 2341 cacaaatcct cattggaacg ttgctgatgt ggttgggtct gaacacaaag aatggatcta 2401 tttccctcat gtgcttggcc ttagggggag tgttgatctt cttatccaca gccgtctctg 2461 ctgatgtggg gtgctcggtg gacttctcaa agaaggagac gagatgcggt acaggggtgt 2521 tcgtctataa cgacgttgaa gcctggaggg acaggtacaa gtaccatcct gactcccccc 2581 gtagattggc agcagcagtc aagcaagcct gggaagatgg tatctgcggg atctcctctg 2641 tttcaagaat ggaaaacatc atgtggagat cagtagaagg ggagctcaat gcaatcctgg 2701 aagagaatgg agttcaactg acggtcgttg tgggatctgt aaaaaacccc atgtggagag 2761 gtccacagag attgcccgtg cctgtgaacg agctgcccca cggctggaag gcttggggga 2821 aatcgtactt cgttagagca gcaaagacaa ataacagctt tgtcgtggat ggtgacacac 2881 tgaaggaatg cccactcaaa catagagcat ggaacagctt tcttgtggag gatcatgggt 2941 tcggggtatt tcacactagt gtctggctca aggttagaga agattattca ttagagtgtg 3001 atccagccgt tattggaaca gctgttaagg gaaaggaggc tgtacacagt gatctaggct 3061 actggattga gagtgagaag aatgacacat ggaggctgaa gagggcccat ctgatcgaga 3121 tgaaaacatg tgaatggcca aagtcccaca cattgtggac agatggaata gaagagagtg 3181 atctgatcat acccaagtct ttagctgggc cactcagcca ccacaatacc agagagggct 3241 ataggaccca aatgaaaggg ccatggcaca gtgaagagct tgaaattcgg tttgaggaat 3301 gcccaggcac taaggtccac gtggaggaaa catgtggaac aagaggacca tctctgagat 3361 caaccactgc aagcggaagg gtgatcgagg aatggtgctg cagggagtgc acaatgcccc 3421 cactgtcgtt ccgggctaaa gatggctgtt ggtatggaat ggagataagg cccaggaaag 3481 aaccagaaag caacttagta aggtcagtgg tgactgcagg atcaactgat cacatggatc 3541 acttctccct tggagtgctt gtgattctgc tcatggtgca ggaagggctg aagaagagaa 3601 tgaccacaaa gatcatcata agcacatcaa tggcagtgct ggtagctatg atcctgggag 3661 gattttcaat gagtgacctg gctaagcttg caattttgat gggtgccacc ttcgcggaaa 3721 tgaacactgg aggagatgta gctcatctgg cgctgatagc ggcattcaaa gtcagaccag 3781 cgttgctggt atctttcatc ttcagagcta attggacacc ccgtgaaagc atgctgctgg 3841 ccttggcctc gtgtcttttg caaactgcga tctccgcctt ggaaggcgac ctgatggttc 3901 tcatcaatgg ttttgctttg gcctggttgg caatacgagc gatggttgtt ccacgcactg 3961 ataacatcac cttggcaatc ctggctgctc tgacaccact ggcccggggc acactgcttg 4021 tggcgtggag agcaggcctt gctacttgcg gggggtttat gctcctctct ctgaagggaa 4081 aaggcagtgt gaagaagaac ttaccatttg tcatggccct gggactaacc gctgtgaggc 4141 tggtcgaccc catcaacgtg gtgggactgc tgttgctcac aaggagtggg aagcggagct 4201 ggccccctag cgaagtactc acagctgttg gcctgatatg cgcattggct ggagggttcg 4261 ccaaggcaga tatagagatg gctgggccca tggccgcagt cggtctgcta attgtcagtt 4321 acgtggtctc aggaaagagt gtggacatgt acattgaaag agcaggtgac atcacatggg 4381 aaaaagatgc ggaagtcact ggaaacagtc cccggctcga tgtggcgcta gatgagagtg 4441 gtgatttctc cctggtagag gatgacggtc cccccatgag agagatcata ctcaaggtgg 4501 tcctgatgac catctgtggc atgaacccaa tagccatacc ctttgcagct ggagcgtggt 4561 acgtatacgt gaagactgga aaaaggagtg gtgctctatg ggatgtgcct gctcccaagg 4621 aagtaaaaaa gggggagacc acagatggag tgtacagagt aatgactcgt agactgctag 4681 gttcaacaca agttggagtg ggagttatgc aagagggggt ctttcacact atgtggcacg 4741 tcacaaaagg atccgcgctg agaagcggtg aagggagact tgatccatac tggggagatg 4801 tcaagcagga tctggtgtca tactgtggtc catggaagct agatgccgcc tgggacgggc 4861 acagcgaggt gcagctcttg gccgtgcccc ccggagagag agcgaggaac atccagactc 4921 tgcccggaat atttaagaca aaggatgggg acattggagc ggttgcgctg gattacccag 4981 caggaacttc aggatctcca atcctagaca agtgtgggag agtgatagga ctttatggca 5041 atggggtcgt gatcaaaaat gggagttatg ttagtgccat cacccaaggg aggagggagg 5101 aagagactcc tgttgagtgc ttcgagcctt cgatgctgaa gaagaagcag ctaactgtct 5161 tagacttgca tcctggagct gggaaaacca ggagagttct tcctgaaata gtccgtgaag 5221 ctataaaaac aagactccgt actgtgatct tagctccaac cagggttgtc gctgctgaaa 5281 tggaggaagc ccttagaggg cttccagtgc gttatatgac aacagcagtc aatgtcaccc 5341 attctggaac agaaatcgtc gacttaatgt gccatgccac cttcacttca cgtctactac 5401 agccaatcag agtccccaac tataatctgt atattatgga tgaggcccac ttcacagatc 5461 cctcaagtat agcagcaaga ggatacattt caacaagggt tgagatgggc gaggcggctg 5521 ccatcttcat gaccgccacg ccaccaggaa cccgtgacgc atttccggac tccaactcac 5581 caattatgga caccgaagtg gaagtcccag agagagcctg gagctcaggc tttgattggg 5641 tgacggatca ctctggaaaa acagtttggt ttgttccaag cgtgaggaac ggcaatgaga 5701 tcgcagcttg tctgacaaag gctggaaaac gggtcataca gctcagcaga aagacttttg 5761 agacagagtt ccagaaaaca aaacatcaag agtgggactt tgtcgtgaca accgacattt 5821 cagagatggg cgccaacttt aaagctgacc gtgtcataga ttccaggaga tgcctaaagc 5881 cggtcatact tgatggcgag agagtcattc tggctggacc catgcctgtc acacatgcca 5941 gcgctgccca gaggaggggg cgcataggca ggaatcccaa caaacctgga gatgagtatc 6001 tgtatggagg tgggtgcgca gagactgacg aagaccatgc acactggctt gaagcaagaa 6061 tgctccttga caatatttac ctccaagatg gcctcatagc ctcgctctat cgacctgagg 6121 ccgacaaagt agcagccatt gagggagagt tcaagcttag gacggagcaa aggaagacct 6181 ttgtggaact catgaaaaga ggagatcttc ctgtttggct ggcctatcag gttgcatctg 6241 ccggaataac ttacacagat agaagatggt gctttgatgg cacgaccaac aacaccataa 6301 tggaagacag tgtgccggca gaggtgtgga ccagacacgg agagaaaaga gtgctcaaac 6361 cgaggtggat ggacgccaga gtttgttcag atcatgcggc cctgaagtca ttcaaggagt 6421 ttgccgctgg gaaaagagga gcggcttttg gagtgatgga agccctggga acactgccag 6481 gacacatgac agagagattc caggaagcca ttgacaacct cgctgtgctc atgcgggcag 6541 agactggaag caggccttac aaagccgcgg cggcccaatt gccggagacc ctagagacca 6601 ttatgctttt ggggttgctg ggaacagtct cgctgggaat ctttttcgtc ttgatgagga 6661 acaagggcat agggaagatg ggctttggaa tggtgactct tggggccagc gcatggctca 6721 tgtggctctc ggaaattgag ccagccagaa ttgcatgtgt cctcattgtt gtgttcctac 6781 tgctggtggt gctcatacct gagccagaaa agcaaagatc tccccaggac aaccaaatgg 6841 caatcatcat catggtagca gtaggtcttc tgggcttgat caccgccaat gaactcggat 6901 ggttggagag aacaaagagt gacctaagcc atctaatggg aaggagagag gagggagcaa 6961 ccataggatt ctcaatggac attgacctgc ggccagcctc agcttgggcc atctatgctg 7021 ccttgacaac tttcatcacc ccagccgtcc aacatgcagt gaccacttca tacaacaact 7081 actccttaat ggcgatggcc acgcaagctg gagtgttgtt tggtatgggc aaagggatgc 7141 cattctacgc atgggacttt ggagtcccgc tgctaatgat aggttgctac tcacaattaa 7201 cacccctgac cctaatagtg gccatcattt tgctcgtggc gcactacatg tacttgatcc 7261 cagggctgca ggcagcagct gcgcgtgctg cccagaagag aacggcagct ggcatcatga 7321 agaaccctgt tgtggatgga atagtggtga ctgacattga cacaatgaca attgaccccc 7381 aagtggagaa aaagatggga caggtgctac tcatagcagt agccgtctcc agcgccatac 7441 tgtcgcggac cgcctggggg tggggggagg ctggggccct gatcacagcc gcaacttcca 7501 ctttgtggga aggctctccg aacaagtact ggaactcctc tacagccact tcactgtgta 7561 acatttttag gggaagttac ttggctggag cttctctaat ctacacagta acaagaaacg 7621 ctggcttggt caagagacgt gggggtggaa caggagagac cctgggagag aaatggaagg 7681 cccgcttgaa ccagatgtcg gccctggagt tctactccta caaaaagtca ggcatcaccg 7741 aggtgtgcag agaagaggcc cgccgcgccc tcaaggacgg tgtggcaacg ggaggccatg 7801 ctgtgtcccg aggaagtgca aagctgagat ggttggtgga gcggggatac ctgcagccct 7861 atggaaaggt cattgatctt ggatgtggca gagggggctg gagttactac gccgccacca 7921 tccgcaaagt tcaagaagtg aaaggataca caaaaggagg ccctggtcat gaagaacccg 7981 tgttggtgca aagctatggg tggaacatag tccgtctcaa gagtggggtg gacgtctttc 8041 atatggcggc tgagccgtgt gacacgttgc tgtgtgacat aggcgagtca tcatctagtc 8101 ctgaagtcga agaagcacgg acgctcagag tcctctccat ggtgggggat tggcttgaaa 8161 aaagaccagg agccttttgt ataaaagtgt tgtgcccata caccagcact atgatggaaa 8221 ccctggagcg actgcagcgt aggtatgggg gaggactggt cagagtgcca ctctcccgca 8281 actctacaca tgagatgtac tgggtttctg gagcgaaaag caacaccata aaaagtgtgt 8341 ccaccacgag ccagctcctc ttggggcgca tggacgggcc taggaggcca gtgaaatatg 8401 aggaggatgt gaatctcggc tctggcacgc gggctgtggt aagctgcgct gaagctccca 8461 acatgaagat cattggtaac cgcattgaaa ggatccgcag tgagcacgcg gaaacgtggt 8521 tctttgacga gaaccaccca tataggacat gggcttacca tggaagctat gaggccccca 8581 cacaagggtc agcatcctct ctagtaaacg gggttgtcag gctcctgtca aaaccctggg 8641 atgtggtgac tggagtcaca ggaatagcca tgaccgacac cacaccgtat ggtcagcaaa 8701 gagttttcaa ggaaaaagtg gacactaggg tgccagaccc ccaagaaggc actcgtcagg 8761 ttatgagcat ggtctcttcc tggttgtgga aagagctagg caaacacaaa cggccacgag 8821 tctgtaccaa agaagagttc atcaacaagg ttcgtagcaa tgcagcatta ggggcaatat 8881 ttgaagagga aaaagagtgg aagactgcag tggaagctgt gaacgatcca aggttctggg 8941 ctctagtgga caaggaaaga gagcaccacc tgagaggaga gtgccagagt tgtgtgtaca 9001 acatgatggg aaaaagagaa aagaaacaag gggaatttgg aaaggccaag ggcagccgcg 9061 ccatctggta tatgtggcta ggggctagat ttctagagtt cgaagccctt ggattcttga 9121 acgaggatca ctggatgggg agagagaact caggaggtgg tgttgaaggg ctgggattac 9181 aaagactcgg atatgtccta gaagagatga gtcgcatacc aggaggaagg atgtatgcag 9241 atgacactgc tggctgggat acccgcatca gcaggtttga tctagagaat gaagctctaa 9301 tcaccaacca aatggagaaa gggcacaggg ccttggcatt ggccataatc aagtacacat 9361 accaaaacaa agtggtaaag gtccttagac cagctgaaaa agggaaaaca gttatggaca 9421 ttatttcgag acaagaccaa agggggagcg gacaagtcgt cacttacgct cttaacacat 9481 ttaccaacct agtggtgcaa ctcattcgga atatggaggc tgaggaagtt ctagagatgc 9541 aagacttgtg gctgctgcgg aggtcagaga aagtgaccaa ctggttgcag agcaacggat 9601 gggataggct caaacgaatg gcagtcagtg gagatgattg cgttgtgaag ccaattgatg 9661 ataggtttgc acatgccctc aggttcttga atgatatggg aaaagttagg aaggacacac 9721 aagagtggaa accctcaact ggatgggaca actgggaaga agttccgttt tgctcccacc 9781 acttcaacaa gctccatctc aaggacggga ggtccattgt ggttccctgc cgccaccaag 9841 atgaactgat tggccgggcc cgcgtctctc caggggcggg atggagcatc cgggagactg 9901 cttgcctagc aaaatcatat gcgcaaatgt ggcagctcct ttatttccac agaagggacc 9961 tccgactgat ggccaatgcc atttgttcat ctgtgccagt tgactgggtt ccaactggga 10021 gaactacctg gtcaatccat ggaaagggag aatggatgac cactgaagac atgcttgtgg 10081 tgtggaacag agtgtggatt gaggagaacg accacatgga agacaagacc ccagttacga 10141 aatggacaga cattccctat ttgggaaaaa gggaagactt gtggtgtgga tctctcatag 10201 ggcacagacc gcgcaccacc tgggctgaga acattaaaaa cacagtcaac atggtgcgca 10261 ggatcatagg tgaggaagaa aagtacatgg actacctatc cacccaagtt cgctacttgg 10321 gtgaagaagg gtctacacct ggagtgctgt aagcaccaat cttaatgttg tcaggcctgc 10381 tagtcagcca cagcttgggg aaagctgtgc agcctgtgac ccccccagga gaagctggga 10441 aaccaagcct atagtcaggc cgagaacgcc atggcacgga agaagccatg ctgcctgtga 10501 gcccctcaga ggacactgag tcaaaaaacc ccacgcgctt ggaggcgcag gatgggaaaa 10561 gaaggtggcg accttcccca cccttcaatc tggggcctga actggagat