niman

England/CLIMB-CM7YFM4D/2023 East of England 8/26/23 collection S:V483del NSP3:P153L NSP2:Y441C NSP3:K1155R BA.2.86.1

map update https://www.google.com/maps/d/u/1/edit?mid=1OCfYIWOx61CCNsWu-FDaiTeSYn066gY&ll=52.427245147395865%2C0.12370636988726869&z=9

England/CLIMB-CM7YKTG8/2023 East of England 8/26/23 collection S:V483del NSP3:P153L NSP2:Y441C NSP3:K1155R BA.2.86.1

map update https://www.google.com/maps/d/u/1/edit?mid=1OCfYIWOx61CCNsWu-FDaiTeSYn066gY&ll=52.42812397490462%2C0.22807734341037111&z=9

England/CLIMB-CM7YREUP/2023 East of England 8/26/23 collection S:V483del NSP3:P153L NSP2:Y441C NSP3:K1155R BA.2.86.1

Note that the combination of NSP3:P153L (ORF1ab:P971L) with S:P681R identifies the England cluster as well as 12,504 Delta sequences circulating in circa 2021 (including 6,560 in USA)

On 21 August 2023 UKHSA was notified of an outbreak in a care home in the East of England with reports of an increased number of cases and increased severity compared to previous outbreaks at the home. All residents and symptomatic or lateral flow device (LFD) positive staff members were polymerase chain reaction (PCR) tested and PCR positive samples were referred to UKHSA for sequencing. As of 5 September 2023, 33 out of 38 residents have tested positive for SARS-CoV-2 (attack rate 86.6%). Of the 33 positive residents, 19 (57.6%) were symptomatic with symptom onset between the 20 August 2023 and 28 August 2023; 29 of the residents have now recovered, while 4 remain unwell. One resident was hospitalised as a result of their illness (hospitalisation rate, 3.0%), and no deaths due to COVID-19 have been reported. Twelve staff tested positive either by LFD and/or PCR, and all have now recovered. No staff members were hospitalised. https://www.gov.uk/government/publications/investigation-of-sars-cov-2-variants-technical-briefings/sars-cov-2-variant-surveillance-and-assessment-technical-briefing-53

map update https://www.google.com/maps/d/u/1/edit?mid=1OCfYIWOx61CCNsWu-FDaiTeSYn066gY&ll=55.89454937155562%2C-4.331962140319132&z=13

Scotland/CLIMB-CM7YFCYP/2023 2023-08-26 collection S V483del NSP3 K1155R BA.2.86.1

map update https://www.google.com/maps/d/u/1/edit?mid=1OCfYIWOx61CCNsWu-FDaiTeSYn066gY&ll=51.677371396378106%2C-0.6152150378841714&z=10

England/CLIMB-CM7Y8QQI/2023 collected 8/28/23 NSP3:P153L NSP2:Y441C NSP3:K1155R BA.2.86.1

map update https://www.google.com/maps/d/u/1/edit?mid=1OCfYIWOx61CCNsWu-FDaiTeSYn066gY&ll=51.77264480182556%2C-0.6152150378841714&z=10

England/CLIMB-CM7YKSNI/2023 England 8/27/2023 collection S:D1139N S:V283del NSP3:P153L NSP2:Y441C NSP3:K1155R BA.2.86.1

map update https://www.google.com/maps/d/u/1/edit?mid=1OCfYIWOx61CCNsWu-FDaiTeSYn066gY&ll=49.09094069292524%2C2.1012844469672354&z=10

France/IDF-IPP18077/2023 L'Isle-Adam collected 8/28/23 Spike ins16MPLF, V483del NSP3 K1155R BA.2.86.1

As of 4 September 2023, there are 34 BA.2.86 sequenced cases in England, with cases located in East of England, London, and North West England. Of 34 total cases in England, 5 were hospitalised (2 have unknown hospitalisation status), and no deaths due to COVID-19 have been reported. These cases include 28 sequenced as part of an investigation of an outbreak in a care home which reported a high attack rate. https://www.gov.uk/government/publications/investigation-of-sars-cov-2-variants-technical-briefings/sars-cov-2-variant-surveillance-and-assessment-technical-briefing-53

As of 4 September 2023, there are 34 BA.2.86 sequenced cases in England, with cases located in East of England, London, and North West England. Of 34 total cases in England, 5 were hospitalised (2 have unknown hospitalisation status), and no deaths due to COVID-19 have been reported. These cases include 28 sequenced as part of an investigation of an outbreak in a care home which reported a high attack rate. https://www.gov.uk/government/publications/investigation-of-sars-cov-2-variants-technical-briefings/sars-cov-2-variant-surveillance-and-assessment-technical-briefing-53

As of 4 September 2023, there are 34 BA.2.86 sequenced cases in England, with cases located in East of England, London, and North West England. Of 34 total cases in England, 5 were hospitalised (2 have unknown hospitalisation status), and no deaths due to COVID-19 have been reported. These cases include 28 sequenced as part of an investigation of an outbreak in a care home which reported a high attack rate. https://www.gov.uk/government/publications/investigation-of-sars-cov-2-variants-technical-briefings/sars-cov-2-variant-surveillance-and-assessment-technical-briefing-53

map update https://www.google.com/maps/d/u/1/edit?mid=1OCfYIWOx61CCNsWu-FDaiTeSYn066gY&ll=51.677371396378106%2C-0.6152150378841714&z=10

England/CLIMB-CM7Y8QQI/2023 collected 8/28/23 not at GISAID NSP3:P153L NSP2:Y441C NSP3:K1155R BA.2.86.1

map update https://www.google.com/maps/d/u/1/edit?mid=1OCfYIWOx61CCNsWu-FDaiTeSYn066gY&ll=51.77264480182556%2C-0.6152150378841714&z=10

England/CLIMB-CM7YKSNI/2023 England 8/27/2023 collection not at GISAID S:D1139N NSP3:P153L NSP2:Y441C NSP3:K1155R BA.2.86.1

map update https://www.google.com/maps/d/u/1/edit?mid=1OCfYIWOx61CCNsWu-FDaiTeSYn066gY&ll=51.814263832775694%2C-0.4737660632747964&z=10

England/CLIMB-CM7YR8JE/2023 England 8/26/23 collection Not at GISAID NSP3:P153L NSP2:Y441C NSP3:K1155R BA.2.86.1

map update https://www.google.com/maps/d/u/1/edit?mid=1OCfYIWOx61CCNsWu-FDaiTeSYn066gY&ll=51.786413990761545%2C-0.20734760624354642&z=10