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Woman tests positive for Zika virus at Chicago North Side hospitalPOSTED 11:27 AM, FEBRUARY 29, 2016, BY WGN WEB DESKFACEBOOK281TWITTERGOOGLELINKEDINPINTERESTEMAIL CHICAGO — The fifth case of the Zika virus in Illinois has been reported at a Chicago hospital. Doctors at Presence Saint Joseph Hospital on the city’s North Side announced at 11 a.m. Monday that a woman tested positive for the virus. The patient was tested because she recently traveled to Colombia, and had symptoms consistent with the Zika virus. There are three confirmed cases of the Zika virus in Illinois, but this is the first case in Chicago. http://wgntv.com/2016/02/29/woman-tests-positive-for-zika-virus-at-chicago-north-side-hospital/

First Zika case in Chicago reported.

Map update https://www.google.com/maps/d/edit?hl=en&hl=en&authuser=0&authuser=0&mid=zv94AJqgUct4.kT4qLMXp3SLU

Texas has had 14 confirmed cases of Zika virus disease. 13 were in travelers who were infected abroad and diagnosed after they returned home. One case involved a Dallas County resident who had sexual contact with someone who acquired the Zika infection while traveling abroad. Case counts by county: Bexar County – 3Dallas County – 2Harris County – 7Travis County - 2 http://www.texaszika.org/

Texas has had 14 confirmed cases of Zika virus disease. 13 were in travelers who were infected abroad and diagnosed after they returned home. One case involved a Dallas County resident who had sexual contact with someone who acquired the Zika infection while traveling abroad. Case counts by county: Bexar County – 3Dallas County – 2Harris County – 7Travis County - 2

29 February 2016CHP notified of ninth imported case of Zika Virus Infection in Mainland The Centre for Health Protection (CHP) of the Department of Health (DH) received notification today (February 29) of the ninth imported case of Zika Virus Infection in the Mainland from the National Health and Family Planning Commission and the Health and Family Planning Commission of Guangdong Province, and again urged the public, particularly pregnant women, those planning pregnancy and immunocompromised patients, to adopt strict anti-mosquito measures during travel. According to the health authorities in the Mainland, the male patient aged 23 lives in Venezuela and arrived in Guangdong on February 19. He developed skin rash on February 26 and sought medical attention on the same day. The case was subsequently laboratory confirmed by the Health and Family Planning Commission of Guangdong Province. At present, the male patient is hospitalised for isolation and management in Enping, Guangdong. He is now in stable condition. The patient did not pass through Hong Kong. "Routine health surveillance on the body temperature of inbound travellers at all boundary control points is ongoing. Suspected cases will be referred to healthcare facilities for follow-up. However, at present, around 70 to 80 per cent of infected people are asymptomatic and most can recover fully. Therefore, we again urge those arriving from Zika-affected areas to apply insect repellent for 14 days upon arrival to reduce the risk of transmission," the spokesman for the DH said. The DH has been closely working with the travel industry and stakeholders, especially agents operating tours in Zika-affected areas and personnel receiving travellers in those areas (particularly pregnant women), to regularly update them on the latest disease information and health advice. As long as there is international travel, there is always a risk of introduction of Zika virus to Hong Kong. As asymptomatic infection is very common and the potential vector, Aedes albopictus, is present locally, there is also risk of local spread in case Zika is introduced to Hong Kong. The public should pay special attention to the countries and areas with reported autochthonous Zika virus transmission or locally acquired infection and those with indication of viral circulation earlier announced by the World Health Organization (WHO). The DH has been maintaining close liaison with the WHO as well as overseas, neighbouring and Mainland health authorities to closely monitor the latest developments of Zika. Locally, no human Zika cases have been reported to the CHP to date. To prevent Zika Virus Infection, in addition to general anti-mosquito measures, the DH drew the public's attention to the special notes below: A. Travelling abroad * If going to areas with ongoing Zika transmission (affected areas), travellers, especially those with immune disorders or severe chronic illnesses, should arrange consultation with a doctor at least six weeks before the trip, and take extra preventive measures to avoid mosquito bites;* Those arriving from affected areas should apply insect repellent for 14 days upon arrival. If feeling unwell, e.g. having fever, they should seek medical advice as soon as possible, and provide travel details to a doctor; B. Pregnant women and those preparing for pregnancy * Pregnant women and those preparing for pregnancy should consider deferring their trip to affected areas. Those who must travel should seek medical advice from their doctor before the trip, adopt contraception if appropriate, strictly follow steps to avoid mosquito bites during the trip, and consult and reveal their travel history to their doctor if symptoms develop after the trip. Women preparing for pregnancy are advised to continue to adopt contraception for 28 days after returning from these areas; and C. Special notes for prevention of sexual transmission regarding potential adverse pregnancy outcomes * Pregnant women should not have sex with male partners who have travelled to areas with ongoing Zika virus transmission, or else condoms should be used throughout the pregnancy;* Any male traveller returning from affected areas should:(i) abstain from sex with his pregnant partner, or else use condoms throughout the pregnancy; and(ii) use a condom for at least six months if his female partner may get pregnant. The public may visit the pages below for more disease information and health advice: * The CHP's Zika page (www.chp.gov.hk/en/view_content/43086.html);* The Zika page of the DH's Travel Health Service (www.travelhealth.gov.hk/english/popup/popup_zika.html);* The Outbound Travel Alert page of the Security Bureau (www.sb.gov.hk/eng/ota); and* Anti-mosquito precautions for women (www.fhs.gov.hk/english/health_info/woman/30014.html). Ends/Monday, February 29, 2016http://www.chp.gov.hk/en/content/116/43650.html

Guangdong Reports Another Imported Zika Case 2016-02-29 19:55:01 Xinhua Web Editor: Mao Yaqing China's southern province of Guangdong has confirmed a new Zika infection on Monday. [File Photo: Xinhua] China's southern province of Guangdong reported a new Zika infection on Monday, according to local health authorities. The patient, a 23-year-old man living in Enping City, which is administered by the city of Jiangmen, returned from Venezuela on Feb. 19, according to the Guangdong Provincial Health and Family Planning Commission. 'The man went to a local hospital after developing a rash on Friday. He was confirmed to have contracted the Zika virus on Monday, and is receiving treatment in a hospital. He is now in stable condition, the commission said. Symptoms of the Zika virus, which is spread to humans through mosquito bites, include fever, joint pain, rash, conjunctivitis, headache and muscle pain. The National Health and Family Planning Commission has urged the public to stay vigilant as the spread of the illness could be possible in some regions as warming weather brings an increase in the mosquito population. http://english.cri.cn/12394/2016/02/29/2702s918492.htm

Sequences producing significant alignments:Select:AllNone Selected:0 AlignmentsDownloadGenBankGraphicsDistance tree of resultsShow/hide columns of the table presenting sequences producing significant alignmentsSequences producing significant alignments:Select for downloading or viewing reportsDescriptionMax scoreTotal scoreQuery coverE valueIdentAccessionSelect seq gb|KU761564.1|Zika virus isolate GDZ16001 polyprotein gene, complete cds1852518525100%0.0100%KU761564.1Select seq gb|KU740184.1|Zika virus isolate GD01 polyprotein gene, complete cds1848918489100%0.099%KU740184.1Select seq gb|KU707826.1|Zika virus isolate SSABR1, complete genome1838418384100%0.099%KU707826.1Select seq gb|KU365779.1|Zika virus strain BeH819966 polyprotein gene, complete cds1838418384100%0.099%KU365779.1Select seq gb|KU365778.1|Zika virus strain BeH819015 polyprotein gene, complete cds1838118381100%0.099%KU365778.1Select seq gb|KU501215.1|Zika virus strain PRVABC59, complete genome1837218372100%0.099%KU501215.1Select seq gb|KU365780.1|Zika virus strain BeH815744 polyprotein gene, complete cds1837218372100%0.099%KU365780.1Select seq gb|KU312312.1|Zika virus isolate Z1106033 polyprotein gene, complete cds1837218372100%0.099%KU312312.1Select seq gb|KU365777.1|Zika virus strain BeH818995 polyprotein gene, complete cds1836618366100%0.099%KU365777.1Select seq gb|KU509998.1|Zika virus strain Haiti/1225/2014, complete genome1835418354100%0.099%KU509998.1Select seq gb|KJ776791.1|Zika virus strain H/PF/2013 polyprotein gene, complete cds1834818348100%0.099%KJ776791.1Select seq gb|KU321639.1|Zika virus strain ZikaSPH2015, complete genome1833918339100%0.099%KU321639.1Select seq gb|KU729218.1|Zika virus isolate BeH828305 polyprotein gene, complete cds1833018330100%0.099%KU729218.1Select seq gb|KU501217.1|Zika virus strain 8375 polyprotein gene, complete cds1831818318100%0.099%KU501217.1Select seq gb|KU497555.1|Zika virus isolate Brazil-ZKV2015, complete genome183141831499%0.099%KU497555.1Select seq gb|KU647676.1|Zika virus strain MRS_OPY_Martinique_PaRi_2015 polyprotein gene, complete cds1831218312100%0.099%KU647676.1Select seq gb|KU501216.1|Zika virus strain 103344 polyprotein gene, complete cds1831218312100%0.099%KU501216.1Select seq gb|KU527068.1|Zika virus strain Natal RGN, complete genome1830318303100%0.099%KU527068.1Select seq gb|KU744693.1|Zika virus isolate VE_Ganxian, complete genome1815918159100%0.099%KU744693.1Select seq gb|KU681081.3|Zika virus isolate Zika virus/H.sapiens-tc/THA/2014/SV0127- 14, complete genome1800618006100%0.099%KU681081.3Select seq gb|JN860885.1|Zika virus isolate FSS13025 polyprotein gene, partial cds176991769999%0.098%JN860885.1Select seq gb|KF993678.1|Zika virus strain PLCal_ZV from Canada polyprotein gene, partial cds176521765298%0.099%KF993678.1Select seq gb|EU545988.1|Zika virus polyprotein gene, complete cds1754417544100%0.098%EU545988.1Select seq gb|KU681082.3|Zika virus isolate Zika virus/H.sapiens-tc/PHL/2012/CPC-0740, complete genome1740717407100%0.098%KU681082.3Select seq gb|HQ234499.1|Zika virus isolate P6-740 polyprotein gene, partial cds164111641199%0.095%HQ234499.1

LOCUS KU761564 10401 bp RNA linear VRL 26-FEB-2016 DEFINITION Zika virus isolate GDZ16001 polyprotein gene, complete cds. ACCESSION KU761564 VERSION KU761564.1 GI:1001231706 KEYWORDS . SOURCE Zika virus ORGANISM Zika virus Viruses; ssRNA viruses; ssRNA positive-strand viruses, no DNA stage; Flaviviridae; Flavivirus. REFERENCE 1 (bases 1 to 10401) AUTHORS Wu,D., Guan,D. and Zhang,H. TITLE Genomic analysis of Zika virus from two Chinese returning to Guangdong, China from Venezuela and Samoa February 2016 JOURNAL Unpublished REFERENCE 2 (bases 1 to 10401) AUTHORS Wu,D., Guan,D. and Zhang,H. TITLE Direct Submission JOURNAL Submitted (26-FEB-2016) Guangdong Provincial Center for Disease Control and Prevention, Institute of Microbiology, No. 160, Qunxian Road, Dashi town, Panyu District, Guangzhou City, Guangdong Province 511430, China COMMENT ##Assembly-Data-START## Sequencing Technology :: Sanger dideoxy sequencing ##Assembly-Data-END## FEATURES Location/Qualifiers source 1..10401 /organism="Zika virus" /mol_type="genomic RNA" /isolate="GDZ16001" /isolation_source="saliva" /host="Homo sapiens" /db_xref="taxon:64320" /country="China" /collection_date="12-Feb-2016" /note="type: Asian" CDS 49..10320 /codon_start=1 /product="polyprotein" /protein_id="AML82110.1" /db_xref="GI:1001231707" /translation="MKNPKKKSGGFRIVNMLKRGVARVSPFGGLKRLPAGLLLGHGPI RMVLAILAFLRFTAIKPSLGLINRWGSVGKKEAMEIIKKFKKDLAAMLRIINARKEKK RRGADTSVGIVGLLLTTAMAAEVTRRGSAYYMYLDRNDAGEAISFPTTLGMNKCYIQI MDLGHMCDATMSYECPMLDEGVEPDDVDCWCNTTSTWVVYGTCHHKKGEARRSRRAVT LPSHSTRKLQTRSQTWLESREYTKHLIRVENWIFRNPGFALAAAAIAWLLGSSTSQKV IYLVMILLIAPAYSIRCIGVSNRDFVEGMSGGTWVDVVLEHGGCVTVMAQDKPTVDIE LVTTTVSNMAEVRSYCYEASISDMASDSRCPTQGEAYLDKQSDTQYVCKRTLVDRGWG NGCGLFGKGSLVTCAKFACSKKMTGKSIQPENLEYRIMLSVHGSQHSGMIVNDTGHET DENRAKVEITPNSPRAEATLGGFGSLGLDCEPRTGLDFSDLYYLTMNNKHWLVHKEWF HDIPLPWHAGADTGTPHWNNKEALVEFKDAHAKRQTVVVLGSQEGAVHTALAGALEAE MDGAKGRLSSGHLKCRLKMDKLRLKGVSYSLCTAAFTFTKIPAETLHGTVTVEVQYAG TDGPCKVPAQMAVDMQTLTPVGRLITANPVITESTENSKMMLELDPPFGDSYIVIGVG EKKITHHWHRSGSTIGKAFEATVRGAKRMAVLGDTAWDFGSVGGALNSLGKGIHQIFG AAFKSLFGGMSWFSQILIGTLLMWLGLNTKNGSISLMCLALGGVLIFLSTAVSADVGC SVDFSKKETRCGTGVFVYNDVEAWRDRYKYHPDSPRRLAAAVKQAWEDGICGISSVSR MENIMWRSVEGELNAILEENGVQLTVVVGSVKNPMWRGPQRLPVPVNELPHGWKAWGK SYFVRAAKTNNSFVVDGDTLKECPLKHRAWNSFLVEDHGFGVFHTSVWLKVREDYSLE CDPAVIGTAVKGKEAVHSDLGYWIESEKNDTWRLKRAHLIEMKTCEWPKSHTLWTDGI EESDLIIPKSLAGPLSHHNTREGYRTQMKGPWHSEELEIRFEECPGTKVHVEETCGTR GPSLRSTTASGRVIEEWCCRECTMPPLSFRAKDGCWYGMEIRPRKEPESNLVRSMVTA GSTDHMDHFSLGVLVILLMVQEGLKKRMTTKIIISTSMAVLVAMILGGFSMSDLAKLA ILMGATFAEMNTGGDVAHLALIAAFKVRPALLVSFIFRANWTPRESMLLALASCLLQT AISALEGDLMVLINGFALAWLAVRAMVVPRTDNITLAILAALTPLARGTLLVAWRAGL ATCGGFMLLSLKGKGSVKKNLPFVMALGLTAVRLVDPINVVGLLLLTRSGKRSWPPSE VLTAVGLICALAGGFAKADIEMAGPMAAVGLLIVSYVVSGKSVDMYIERAGDITWEKD AEVTGNSPRLDVALDESGDFSLVEDDGPPMREIILKVVLMTICGMNPIAIPFAAGAWY VYVKTGKRSGALWDVPAPKEVKKGETTDGVYRVMTRRLLGSTQVGVGVMQEGVFHTMW HVTKGSALRSGEGRLDPYWGDVKQDLVSYCGPWKLDAAWDGHSEVQLLAVPPGERARN IQTLPGIFKTKDGDIGAVALDYPAGTSGSPILDKCGRVIGLYGNGVVIKNGSYVSAIT QGRREEETPVECFEPSMLKKKQLTVLDLHPGAGKTRRVLPEIVREAIKTRLRTVILAP TRVVAAEMEEALRGLPVRYMTTAVNVTHSGTEIVDLMCHATFTSRLLQPIRVPNYNLY IMDEAHFTDPSSIAARGYISTRVEMGEAAAIFMTATPPGTRDAFPDSNSPIMDTEVEV PERAWSSGFDWVTDHSGKTVWFVPSVRNGNEIAACLTKAGKRVIQLSRKTFETEFQKT KHQEWDFVVTTDISEMGANFKADRVIDSRRCLKPVILDGERVILAGPMPVTHASAAQR RGRIGRNPNKPGDEYLYGGGCAETDEDHAHWLEARMLLDNIYLQDGLIASLYRPEADK VAAIEGEFKLRTEQRKTFVELMKRGDLPVWLAYQVASAGITYTDRRWCFDGTTNNTIM EDSVPAEVWTRHGEKRVLKPRWMDARVCSDHAALKSFKEFAAGKRGAAFGVMEALGTL PGHMTERFQEAIDNLAVLMRAETGSRPYKAAAAQLPETLETIMLLGLLGTVSLGIFFV LMRNKGIGKMGFGMVTLGASAWLMWLSEIEPARIACVLIVVFLLLVVLIPEPEKQRSP QDNQMAIIIMVAVGLLGLITANELGWLERTKSDLSHLMGRREEGATIGFSMDIDLRPA SAWAIYAALTTFITPAVQHAVTTSYNNYSLMAMATQAGVLFGMGKGMPFYAWDFGVPL LMIGCYSQLTPLTLIVAIILLVAHYMYLIPGLQAAAARAAQKRTAAGIMKNPVVDGIV VTDIDTMTIDPQVEKKMGQVLLIAVAVSSAILSRTAWGWGEAGALITAATSTLWEGSP NKYWNSSTATSLCNIFRGSYLAGASLIYTVTRNAGLVKRRGGGTGETLGEKWKARLNQ MSALEFYSYKKSGITEVCREEARRALKDGVATGGHAVSRGSAKLRWLVERGYLQPYGK VIDLGCGRGGWSYYAATIRKVQEVKGYTKGGPGHEEPVLVQSYGWNIVRLKSGVDVFH MAAEPCDTLLCDIGESSSSPEVEEARTLRVLSMVGDWLEKRPGAFCIKVLCPYTSTMM ETLERLQRRYGGGLVRVPLSRNSTHEMYWVSGAKSNIIKSVSTTSQLLLGRMDGPRRP VKYEEDVNLGSGTRAVASCAEAPNMKIIGNRIERIRSEHAETWFFDENHPYRTWAYHG SYEAPTQGSASSLINGVVRLLSKPWDVVTGVTGIAMTDTTPYGQQRVFKEKVDTRVPD PQEGTRQVMSMVSSWLWKELGKHKRPRVCTKEEFINKVRSNAALGAIFEEEKEWKTAV EAVNDPRFWALVDKEREHHLRGECQSCVYNMMGKREKKQGEFGKAKGSRAIWYMWLGA RFLEFEALGFLNEDHWMGRENSGGGVEGLGLQRLGYVLEEMSRIPGGRMYADDTAGWD TRISRFDLENEALITNQMEKGHRALALAIIKYTYQNKVVKVLRPAEKGKTVMDIISRQ DQRGSGQVVTYALNTFTNLVVQLIRNMEAEEVLEMQDLWLLRRSEKVTNWLQSNGWDR LKRMAVSGDDCVVKPIDDRFAHALRFLNDMGKVRKDTQEWKPSTGWDNWEEVPFCSHH FNKLHLKDGRSIVVPCRHQDELIGRARVSPGAGWSIRETACLAKSYAQMWQLLYFHRR DLRLMANAICSSVPVDWVPTGRTTWSIHGKGEWMTTEDMLVVWNRVWIEENDHMEDKT PVTKWTDIPYLGKREDLWCGSLIGHRPRTTWAENIKNTVNMVRRIIGDEEKYMDYLST QVRYLGEEGSTPGVL" ORIGIN 1 cagtatcaac aggttttatt ttggatttgg aaacgagagt ttctggtcat gaaaaaccca 61 aaaaagaaat ccggaggatt ccggattgtc aatatgctaa aacgcggagt agcccgtgtg 121 agcccctttg ggggcttgaa gaggctgcca gccggacttc tgctgggtca tgggcccatc 181 aggatggtct tggcgattct agccttcttg agattcacgg caatcaagcc atcactgggt 241 ctcatcaata gatggggttc agtggggaaa aaagaggcta tggaaataat aaagaagttc 301 aagaaagatc tggctgccat gctgagaata atcaatgcta ggaaggagaa gaagagacga 361 ggcgcagata ctagtgtcgg aattgttggc ctcctgctga ccacagctat ggcagcggag 421 gtcactagac gtgggagtgc atactatatg tacttggaca gaaacgatgc tggggaggcc 481 atatcttttc caaccacatt ggggatgaat aagtgttata tacagatcat ggatcttgga 541 cacatgtgtg atgccaccat gagctatgaa tgccctatgc tggatgaggg ggtggaacca 601 gatgacgtcg attgttggtg caacacgacg tcaacttggg ttgtgtacgg aacctgccat 661 cacaaaaaag gtgaagcacg gagatctaga agagctgtga cgctcccttc ccattccact 721 aggaagctgc aaacgcggtc gcaaacctgg ttggaatcaa gagaatacac aaagcacttg 781 attagagtcg aaaattggat attcaggaac cctggcttcg cgttagcagc agctgctatc 841 gcttggcttt tgggaagctc aacgagccaa aaagtcatat acttggtcat gatactgctg 901 attgccccgg catacagcat caggtgcata ggagtcagca atagggactt tgtggaaggt 961 atgtcaggtg ggacttgggt tgatgttgtc ttggaacatg gaggttgtgt caccgtaatg 1021 gcacaggaca aaccgactgt cgacatagag ctggttacaa caacagtcag caacatggcg 1081 gaggtaagat cctactgcta tgaggcatca atatcagaca tggcttcgga cagccgctgc 1141 ccaacacaag gtgaagccta ccttgacaag caatcagaca ctcaatatgt ctgcaaaaga 1201 acgttagtgg acagaggctg gggaaatgga tgtggacttt ttggcaaagg gagcctggtg 1261 acatgcgcta agtttgcatg ctccaagaaa atgaccggga aaagcatcca gccagagaat 1321 ctggagtacc ggataatgct gtcagttcat ggctcccagc acagtgggat gatcgttaat 1381 gacacaggac atgaaactga tgagaataga gcgaaagttg agataacgcc caattcacca 1441 agagccgaag ccaccctggg gggttttgga agcctaggac ttgattgtga accgaggaca 1501 ggccttgact tttcagattt gtattacttg actatgaata acaagcactg gttggttcac 1561 aaggagtggt tccacgacat tccattacct tggcacgctg gggcagacac cggaactcca 1621 cactggaaca acaaagaagc actggtagag ttcaaggacg cacatgccaa aaggcaaact 1681 gtcgtggttc tagggagtca agaaggagca gttcacacgg cccttgctgg agctctggag 1741 gctgagatgg atggagcaaa gggaaggctg tcctctggcc acttgaaatg tcgcctgaaa 1801 atggataaac ttagattgaa gggcgtgtca tactccttgt gtactgcagc gttcacattc 1861 accaagatcc cggctgaaac actgcacggg acagtcacag tggaggtaca gtacgcaggg 1921 acagatggac cttgcaaggt tccagctcag atggcggtgg acatgcaaac tctgacccca 1981 gttgggaggt tgataaccgc taaccccgta atcactgaaa gcactgagaa ctctaagatg 2041 atgctggaac ttgatccacc atttggggac tcttacattg tcataggagt cggggagaag 2101 aagatcaccc accactggca caggagtggc agcaccattg gaaaagcatt tgaagccact 2161 gtgagaggtg ccaagagaat ggcagtcttg ggagacacag cctgggactt tggatcagtt 2221 ggaggcgctc tcaactcatt gggcaagggc atccatcaaa tttttggagc agctttcaaa 2281 tcattgtttg gaggaatgtc ctggttctca caaattctca ttggaacgtt gctgatgtgg 2341 ttgggtctga acacaaagaa tggatctatt tcccttatgt gcttggcctt agggggagtg 2401 ttgatcttct tatccacagc cgtctctgct gatgtggggt gctcggtgga cttctcaaag 2461 aaggagacga gatgcggtac aggggtgttt gtctataacg acgttgaagc ctggagggac 2521 aggtacaagt accatcctga ctccccccgt agattggcag cagcagtcaa gcaagcctgg 2581 gaagatggta tctgcgggat ctcctctgtt tcaagaatgg aaaacatcat gtggagatca 2641 gtagaagggg agctcaacgc aatcctggaa gagaatggag ttcaactgac ggtcgttgtg 2701 ggatctgtaa aaaaccccat gtggagaggt ccacagagat tgcccgtgcc tgtgaacgag 2761 ctgccccacg gctggaaggc ttgggggaaa tcgtacttcg tcagagcagc aaagacaaat 2821 aacagctttg tcgtggatgg tgacacactg aaggaatgcc cactcaaaca tagagcatgg 2881 aacagctttc ttgtggagga tcatgggttc ggggtatttc acactagtgt ctggctcaag 2941 gttagagaag actattcatt agagtgtgat ccagccgtta ttggaacagc tgttaaggga 3001 aaggaggctg tacacagtga tctaggctac tggattgaga gtgagaagaa tgacacatgg 3061 aggctgaaga gggcccatct gatcgagatg aaaacatgtg aatggccaaa gtcccacaca 3121 ttgtggacag atggaataga agagagtgat ctgatcatac ccaagtcttt agctgggcca 3181 ctcagccatc acaataccag agagggctac aggacccaaa tgaaagggcc atggcacagt 3241 gaggagcttg aaattcggtt tgaggaatgc ccaggcacta aggtccacgt ggaggaaaca 3301 tgtggaacaa gaggaccatc tctgagatca accactgcaa gcggaagggt gatcgaggaa 3361 tggtgctgca gggagtgcac aatgccccca ctgtcgttcc gggctaaaga tggctgttgg 3421 tatggaatgg agataaggcc caggaaagaa ccagaaagca acttagtaag gtcaatggtg 3481 actgcaggat caactgatca catggaccac ttctcccttg gagtgcttgt gatcctgctc 3541 atggtgcagg aagggctgaa gaagagaatg accacaaaga tcatcataag cacatcaatg 3601 gcagtgctgg tagctatgat cctgggagga ttttcaatga gtgacctggc taagcttgca 3661 attttgatgg gtgccacctt cgcggaaatg aacactggag gagatgtagc tcatctggcg 3721 ctgatagcgg cattcaaagt cagaccagcg ttgctggtat ctttcatctt cagagctaat 3781 tggacacccc gtgaaagcat gctgctggcc ttggcctcgt gtcttttgca aactgcgatc 3841 tccgccttgg aaggcgacct gatggttctc atcaatggtt ttgctttggc ctggttggca 3901 gtacgagcga tggttgttcc acgcactgat aacatcacct tagcaatcct ggctgctctg 3961 acaccactgg cccggggcac actgcttgtg gcgtggagag caggccttgc tacttgcggg 4021 gggtttatgc tcctctctct gaagggaaaa ggcagtgtga agaagaactt accatttgtc 4081 atggccctgg gactaaccgc tgtgaggctg gtcgacccca tcaacgtggt gggactgctg 4141 ttgctcacaa ggagtgggaa gcggagctgg ccccctagcg aagtactcac agctgttggc 4201 ctgatatgcg cattggctgg agggttcgcc aaggcagata tagagatggc tgggcccatg 4261 gccgcggtcg gtctgctaat tgtcagttac gtggtctcag gaaagagtgt ggacatgtac 4321 attgaaagag caggtgacat cacatgggaa aaagatgcgg aagtcactgg aaacagtccc 4381 cggctcgatg tggcgctaga tgagagtggt gatttctccc tggtggagga tgacggtccc 4441 cccatgagag agatcatact caaggtggtc ctgatgacca tctgtggcat gaacccaata 4501 gccataccct ttgcagctgg agcgtggtac gtatacgtga agactggaaa aaggagtggt 4561 gctctatggg atgtgcctgc tcccaaggaa gtaaaaaagg gggagaccac agatggagtg 4621 tacagagtaa tgactcgcag actgctaggt tcaacacaag ttggagtggg agttatgcaa 4681 gagggggtct ttcacactat gtggcacgtc acaaaaggat ccgcgctgag aagcggtgaa 4741 gggagacttg atccatactg gggagatgtc aagcaggatc tggtgtcata ctgtggtcca 4801 tggaagctag atgccgcctg ggacgggcac agcgaggtgc agctcttggc cgtgcccccc 4861 ggagagagag cgaggaacat ccagactctg cccggaatat ttaagacaaa ggatggggac 4921 attggagcgg ttgcgctgga ttacccagca ggaacttcag gatctccaat cctagacaag 4981 tgtgggagag tgataggact ttatggcaat ggggtcgtga tcaaaaatgg gagttatgtt 5041 agtgccatca cccaagggag gagggaggaa gagactcctg ttgagtgctt cgagccttcg 5101 atgctgaaga agaagcagct aactgtctta gacttgcatc ctggagctgg gaaaaccagg 5161 agagttcttc ctgaaatagt ccgtgaagcc ataaaaacaa gactccgtac tgtgatctta 5221 gctccaacca gggttgtcgc tgctgaaatg gaggaggccc ttagagggct tccagtgcgt 5281 tatatgacaa cagcagtcaa tgtcacccac tctggaacag aaatcgtcga cttaatgtgc 5341 catgccacct tcacttcacg tctactacag ccaattagag tccccaacta taatctgtat 5401 attatggatg aggcccactt cacagatccc tcaagtatag cagcaagagg atacatttca 5461 acaagggttg agatgggcga ggcggctgcc atcttcatga ccgccacgcc accaggaacc 5521 cgtgacgcat ttccggactc caactcacca attatggaca ccgaagtgga agtcccagag 5581 agagcctgga gctcaggctt tgattgggtg acggatcatt ctggaaaaac agtttggttt 5641 gttccaagcg tgaggaacgg caatgagatc gcagcttgtc tgacaaaggc tggaaaacgg 5701 gtcatacagc tcagcagaaa gacttttgag acagagttcc agaaaacaaa acatcaagag 5761 tgggactttg tcgtgacaac tgacatttca gagatgggcg ccaactttaa agctgaccgt 5821 gtcatagatt ccaggagatg cctaaagccg gtcatacttg atggcgagag agtcattctg 5881 gctggaccca tgcctgtcac acatgccagc gctgcccaga ggagggggcg cataggcagg 5941 aatcccaaca aacctggaga tgagtatctg tatggaggtg ggtgcgcaga gactgacgaa 6001 gaccatgcac actggcttga agcaagaatg ctccttgaca atatttacct ccaagatggc 6061 ctcatagcct cgctctatcg acctgaggcc gacaaagtag cagccattga gggagagttc 6121 aagcttagga cggagcaaag gaagaccttt gtggaactca tgaaaagagg agatcttcct 6181 gtttggctgg cctatcaggt tgcatctgcc ggaataacct acacagatag aagatggtgc 6241 tttgatggca cgaccaacaa caccataatg gaagacagtg tgccggcaga ggtgtggacc 6301 agacacggag agaaaagagt gctcaaaccg aggtggatgg acgccagagt ttgttcagat 6361 catgcggccc tgaagtcatt caaggagttt gccgctggga aaagaggagc ggcttttgga 6421 gtgatggaag ccctgggaac actgccagga cacatgacag agagattcca ggaagccatt 6481 gacaacctcg ctgtgctcat gcgggcagag actggaagca ggccttacaa agccgcggca 6541 gcccaattgc cggagaccct agagaccatt atgcttttgg ggttgctggg aacagtctcg 6601 ctgggaatct tcttcgtctt gatgaggaac aagggcatag ggaagatggg ctttggaatg 6661 gtgactcttg gggccagcgc atggctcatg tggctctcgg aaattgagcc agccagaatt 6721 gcatgtgtcc tcattgttgt gttcctattg ctggtggtgc tcatacctga gccagaaaag 6781 caaagatctc cccaggacaa ccaaatggca atcatcatca tggtagcagt aggtcttctg 6841 ggcttgatta ccgccaatga actcggatgg ttggagagaa caaagagtga cctaagccat 6901 ctaatgggaa ggagagagga gggggcaacc ataggattct caatggacat tgacctgcgg 6961 ccagcctcag cttgggccat ctatgctgcc ttgacaactt tcattacccc agccgtccaa 7021 catgcagtga ccacctcata caacaactac tccttaatgg cgatggccac gcaagctgga 7081 gtgttgtttg gtatgggcaa agggatgcca ttctacgcat gggactttgg agtcccgctg 7141 ctaatgatag gctgctactc acaattaaca cccctgaccc taatagtggc catcattttg 7201 ctcgtggcgc actacatgta cttgatccca gggctgcagg cagcagctgc gcgtgctgcc 7261 cagaagagaa cggcagctgg catcatgaag aaccctgttg tggatggaat agtggtgact 7321 gacattgaca caatgacaat tgacccccaa gtggagaaaa agatgggaca ggtgctactc 7381 atagcagtag ccgtctccag cgccatactg tcgcggaccg cctgggggtg gggggaggct 7441 ggggccctga tcacagccgc aacttccact ttgtgggaag gctctccgaa caagtactgg 7501 aactcctcta cagccacttc actgtgtaac atttttaggg gaagttactt ggctggagct 7561 tctctaatct acacagtaac aagaaacgct ggcttggtca agagacgtgg gggtggaaca 7621 ggagagaccc tgggagagaa atggaaggcc cgcttgaacc agatgtcggc cctggagttc 7681 tactcctaca aaaagtcagg catcaccgag gtgtgcagag aagaggcccg ccgcgccctc 7741 aaggacggtg tggcaacggg aggccatgct gtgtcccgag gaagtgcaaa gctgagatgg 7801 ttggtggagc ggggatacct gcagccctat ggaaaggtca ttgatcttgg atgtggcaga 7861 gggggctgga gttactacgc cgccaccatc cgcaaagttc aagaagtgaa aggatacaca 7921 aaaggaggcc ctggtcatga agaacccgtg ttggtgcaaa gctatgggtg gaacatagtc 7981 cgtcttaaga gtggggtgga cgtctttcat atggcggctg agccgtgtga cacgttgctg 8041 tgtgacatag gtgagtcatc atctagtcct gaagtggaag aagcacggac gctcagagtc 8101 ctctccatgg tgggggattg gcttgaaaaa agaccaggag ccttttgcat aaaagtgttg 8161 tgcccataca ccagcactat gatggaaacc ctggagcgac tgcagcgtag gtatggggga 8221 ggactggtca gagtgccact ctcccgcaac tctacacatg agatgtactg ggtctctgga 8281 gcgaaaagca acatcataaa aagtgtgtcc accacgagcc agctcctctt ggggcgcatg 8341 gacgggccta ggaggccagt gaaatatgag gaggatgtga atctcggctc tggcacgcgg 8401 gctgtggcaa gctgcgctga agctcccaac atgaagatca ttggtaaccg cattgaaagg 8461 atccgcagtg agcacgcgga aacgtggttc tttgacgaga accacccata taggacatgg 8521 gcttaccatg gaagctatga ggcccccaca caagggtcag cgtcctctct aataaacggg 8581 gttgtcaggc tcctgtcaaa accctgggat gtggtgactg gagtcacagg aatagccatg 8641 accgacacca caccgtatgg tcagcaaaga gttttcaagg aaaaagtgga cactagggtg 8701 ccagaccccc aagaaggcac tcgtcaggtt atgagcatgg tctcttcctg gttgtggaaa 8761 gagctaggca aacacaaacg gccacgagtc tgtaccaaag aagagttcat caacaaggtt 8821 cgtagcaatg cagcattagg ggcaatattt gaagaggaaa aagagtggaa gactgcagtg 8881 gaagctgtga acgatccaag gttctgggct ctagtggaca aggaaagaga gcaccacctg 8941 agaggagagt gccagagttg tgtgtacaac atgatgggaa aaagagaaaa gaaacaaggg 9001 gaatttggaa aggccaaggg cagccgcgcc atctggtata tgtggctggg ggctagattt 9061 ctagagttcg aagcccttgg attcttgaac gaggatcact ggatggggag agagaactca 9121 ggaggtggtg ttgaagggct gggattacaa agactcggat atgtcctaga agagatgagt 9181 cgtataccag gaggaaggat gtatgcagat gacactgctg gctgggacac ccgcattagc 9241 aggtttgatc tggagaatga agctctaatc accaaccaaa tggagaaagg gcacagggcc 9301 ttggcattgg ccataatcaa gtacacatac caaaacaaag tggtaaaggt ccttagacca 9361 gctgaaaaag ggaaaacagt tatggacatt atttcgagac aagaccaaag ggggagcgga 9421 caagttgtca cttacgctct taacacattt accaacctag tggtgcaact cattcggaat 9481 atggaggctg aggaagttct agagatgcaa gacttgtggc tgctgcggag gtcagagaaa 9541 gtgaccaact ggttgcagag caacggatgg gataggctca aacgaatggc agtcagtgga 9601 gatgattgcg ttgtgaagcc aattgatgat aggtttgcac atgccctcag gttcttgaat 9661 gatatgggaa aagttaggaa ggacacacaa gagtggaaac cctcaactgg atgggacaac 9721 tgggaagaag ttccgttttg ctcccaccat ttcaacaagc tccatctcaa ggacgggagg 9781 tccattgtgg ttccctgccg ccaccaagat gaactgattg gccgggcccg cgtctctcca 9841 ggggcgggat ggagcatccg ggagactgct tgcctagcaa aatcatatgc gcaaatgtgg 9901 cagctccttt atttccacag aagggacctc cgactgatgg ccaatgccat ttgttcatct 9961 gtgccagttg actgggttcc aactgggaga actacctggt caatccatgg aaagggagaa 10021 tggatgacca ctgaagacat gcttgtggtg tggaacagag tgtggattga ggagaacgac 10081 cacatggaag acaagacccc agttacgaaa tggacagaca ttccctattt gggaaaaagg 10141 gaagacttgt ggtgtggatc tctcataggg cacagaccgc gcaccacctg ggctgagaac 10201 attaaaaaca cagtcaacat ggtgcgcagg atcataggtg atgaagaaaa gtacatggat 10261 tacctatcca cccaagttcg ctacttgggt gaagaagggt ctacacctgg agtgctgtaa 10321 gcaccaatct taatgttgtc aggcctgcta gtcagccaca gcttggggaa agctgtgcag 10381 cctgtgaccc ccccaggaga a

LOCUS KU761564 10401 bp RNA linear VRL 26-FEB-2016 DEFINITION Zika virus isolate GDZ16001 polyprotein gene, complete cds. ACCESSION KU761564 VERSION KU761564.1 GI:1001231706 KEYWORDS . SOURCE Zika virus ORGANISM Zika virus Viruses; ssRNA viruses; ssRNA positive-strand viruses, no DNA stage; Flaviviridae; Flavivirus. REFERENCE 1 (bases 1 to 10401) AUTHORS Wu,D., Guan,D. and Zhang,H. TITLE Genomic analysis of Zika virus from two Chinese returning to Guangdong, China from Venezuela and Samoa February 2016 JOURNAL Unpublished REFERENCE 2 (bases 1 to 10401) AUTHORS Wu,D., Guan,D. and Zhang,H. TITLE Direct Submission JOURNAL Submitted (26-FEB-2016) Guangdong Provincial Center for Disease Control and Prevention, Institute of Microbiology, No. 160, Qunxian Road, Dashi town, Panyu District, Guangzhou City, Guangdong Province 511430, China COMMENT ##Assembly-Data-START## Sequencing Technology :: Sanger dideoxy sequencing ##Assembly-Data-END## FEATURES Location/Qualifiers source 1..10401 /organism="Zika virus" /mol_type="genomic RNA" /isolate="GDZ16001" /isolation_source="saliva" /host="Homo sapiens" /db_xref="taxon:64320" /country="China" /collection_date="12-Feb-2016" /note="type: Asian"

Guangdong Provincial Center for Disease Control and Prevention has released a full sequence from the saliva, GDZ16001, collected on February 12 from a Guangzhou traveler returning from Venezuela. The saliva sequence was virtually identical to a serum sample, GD01,from the same patient.

Sequences producing significant alignments:Select:AllNone Selected:0 AlignmentsDownloadGenBankGraphicsDistance tree of resultsShow/hide columns of the table presenting sequences producing significant alignmentsSequences producing significant alignments:Select for downloading or viewing reportsDescriptionMax scoreTotal scoreQuery coverE valueIdentAccessionSelect seq gb|KU761564.1|Zika virus isolate GDZ16001 polyprotein gene, complete cds1852518525100%0.0100%KU761564.1Select seq gb|KU740184.1|Zika virus isolate GD01 polyprotein gene, complete cds1848918489100%0.099%KU740184.1Select seq gb|KU707826.1|Zika virus isolate SSABR1, complete genome1838418384100%0.099%KU707826.1Select seq gb|KU365779.1|Zika virus strain BeH819966 polyprotein gene, complete cds1838418384100%0.099%KU365779.1Select seq gb|KU365778.1|Zika virus strain BeH819015 polyprotein gene, complete cds1838118381100%0.099%KU365778.1Select seq gb|KU501215.1|Zika virus strain PRVABC59, complete genome1837218372100%0.099%KU501215.1Select seq gb|KU365780.1|Zika virus strain BeH815744 polyprotein gene, complete cds1837218372100%0.099%KU365780.1Select seq gb|KU312312.1|Zika virus isolate Z1106033 polyprotein gene, complete cds1837218372100%0.099%KU312312.1Select seq gb|KU365777.1|Zika virus strain BeH818995 polyprotein gene, complete cds1836618366100%0.099%KU365777.1Select seq gb|KU509998.1|Zika virus strain Haiti/1225/2014, complete genome1835418354100%0.099%KU509998.1Select seq gb|KJ776791.1|Zika virus strain H/PF/2013 polyprotein gene, complete cds1834818348100%0.099%KJ776791.1Select seq gb|KU321639.1|Zika virus strain ZikaSPH2015, complete genome1833918339100%0.099%KU321639.1Select seq gb|KU729218.1|Zika virus isolate BeH828305 polyprotein gene, complete cds1833018330100%0.099%KU729218.1Select seq gb|KU501217.1|Zika virus strain 8375 polyprotein gene, complete cds1831818318100%0.099%KU501217.1Select seq gb|KU497555.1|Zika virus isolate Brazil-ZKV2015, complete genome183141831499%0.099%KU497555.1Select seq gb|KU647676.1|Zika virus strain MRS_OPY_Martinique_PaRi_2015 polyprotein gene, complete cds1831218312100%0.099%KU647676.1Select seq gb|KU501216.1|Zika virus strain 103344 polyprotein gene, complete cds1831218312100%0.099%KU501216.1Select seq gb|KU527068.1|Zika virus strain Natal RGN, complete genome1830318303100%0.099%KU527068.1Select seq gb|KU744693.1|Zika virus isolate VE_Ganxian, complete genome1815918159100%0.099%KU744693.1Select seq gb|KU681081.3|Zika virus isolate Zika virus/H.sapiens-tc/THA/2014/SV0127- 14, complete genome1800618006100%0.099%KU681081.3Select seq gb|JN860885.1|Zika virus isolate FSS13025 polyprotein gene, partial cds176991769999%0.098%JN860885.1Select seq gb|KF993678.1|Zika virus strain PLCal_ZV from Canada polyprotein gene, partial cds176521765298%0.099%KF993678.1Select seq gb|EU545988.1|Zika virus polyprotein gene, complete cds1754417544100%0.098%EU545988.1Select seq gb|KU681082.3|Zika virus isolate Zika virus/H.sapiens-tc/PHL/2012/CPC-0740, complete genome1740717407100%0.098%KU681082.3Select seq gb|HQ234499.1|Zika virus isolate P6-740 polyprotein gene, partial cds164111641199%0.095%HQ234499.1Select seq gb|KU720415.1|Zika virus strain MR 766 polyprotein gene, complete cds1330413304100%0.089%KU720415.1Select seq gb|HQ234498.1|Zika virus isolate MR_766 polyprotein gene, partial cds132991329999%0.089%HQ234498.1Select seq gb|KF268949.1|Zika virus isolate ARB15076 polyprotein gene, complete cds1329713297100%0.089%KF268949.1Select seq gb|KF383115.1|Zika virus strain ArB1362 polyprotein gene, complete cds1329313293100%0.089%KF383115.1Select seq gb|KF268948.1|Zika virus isolate ARB13565 polyprotein gene, complete cds1328813288100%0.089%KF268948.1Select seq dbj|LC002520.1|Zika virus genomic RNA, complete genome, strain: MR766-NIID1328113281100%0.089%LC002520.1Select seq gb|KF268950.1|Zika virus isolate ARB7701 polyprotein gene, complete cds1328113281100%0.089%KF268950.1Select seq gb|KF383119.1|Zika virus strain ArD158084 polyprotein gene, complete cds1327713277100%0.089%KF383119.1Select seq gb|DQ859059.1|Zika virus strain MR 766 polyprotein gene, complete cds1327513275100%0.089%DQ859059.1Select seq gb|KF383116.1|Zika virus strain ArD7117 polyprotein gene, complete cds1326113261100%0.089%KF383116.1Select seq gb|HQ234501.1|Zika virus isolate ArD_41519 polyprotein gene, partial cds132451324599%0.089%HQ234501.1Select seq gb|AY632535.2|Zika virus strain MR 766, complete genome1322313223100%0.089%AY632535.2Select seq gb|KF383117.1|Zika virus strain ArD128000 polyprotein gene, complete cds1319113191100%0.088%KF383117.1Select seq gb|HQ234500.1|Zika virus isolate IbH_30656 polyprotein gene, partial cds131831318399%0.088%HQ234500.1Select seq gb|KF383118.1|Zika virus strain ArD157995 polyprotein gene, complete cds1296313031100%0.088%KF383118.1Select seq gb|KF383121.1|Zika virus strain ArD158095 polyprotein gene, partial cds128791287997%0.089%KF383121.1Select seq gb|KU729217.1|Zika virus isolate BeH823339 polyprotein gene, complete cds119261694592%0.099%KU729217.1Select seq gb|KF383120.1|Zika virus strain ArD142623 nonfunctional polyprotein gene, partial sequence109081090897%0.084%KF383120.1Select seq gb|KU312314.1|Zika virus isolate Z1106031 polyprotein gene, partial cds4980498027%0.099%KU312314.1Select seq gb|KU312313.1|Zika virus isolate Z1106032 polyprotein gene, partial cds4953495327%0.099%KU312313.1Select seq gb|KU646828.1|Zika virus isolate Si322 polyprotein gene, partial cds4637463725%0.099%KU646828.1Select seq gb|KU646827.1|Zika virus isolate Si323 polyprotein gene, partial cds4628462825%0.099%KU646827.1Select seq gb|KU312315.1|Zika virus isolate Z1106027 polyprotein gene, partial cds3449344918%0.099%KU312315.1Select seq gb|KU740199.1|Zika virus isolate VE_Ganxian2016 polyprotein gene, partial cds3247324717%0.099%KU740199.1Select seq gb|DQ859064.1|Spondweni virus strain SM-6 V-1 polyprotein gene, complete cds2883423395%0.071%DQ859064.1Select seq gb|KJ634273.1|Zika virus strain CK-ISL 2014 E protein (E) gene, partial cds2686268614%0.099%KJ634273.1Select seq gb|KU686218.1|Zika virus isolate MEX/InDRE/14/2015 polyprotein gene, partial cds2048204811%0.099%KU686218.1Select seq gb|KU179098.1|Zika virus isolate JMB-185 nonstructural protein 5 gene, partial cds2008200811%0.099%KU179098.1Select seq gb|KM078936.1|Zika virus strain CHI1410214 NS5 protein gene, partial cds173717379%0.099%KM078936.1Select seq gb|KM078961.1|Zika virus strain CHI2612114 NS5 protein gene, partial cds173617369%0.099%KM078961.1Select seq gb|KM078930.1|Zika virus strain CHI2283714 NS5 protein gene, partial cds173417349%0.099%KM078930.1Select seq gb|KM078971.1|Zika virus strain CHI2613014 NS5 protein gene, partial cds173017309%0.099%KM078971.1Select seq gb|KM078970.1|Zika virus strain CHI2490414 NS5 protein gene, partial cds173017309%0.099%KM078970.1Select seq gb|KM078933.1|Zika virus strain CHI1058514 NS5 protein gene, partial cds173017309%0.099%KM078933.1Select seq gb|KM078929.1|Zika virus strain CHI1805214 NS5 protein gene, partial cds172817289%0.099%KM078929.1Select seq gb|KJ873160.1|Zika virus isolate NC14-03042014-3481 nonstructural protein 5 gene, partial cds159315938%0.099%KJ873160.1Select seq gb|KJ873161.1|Zika virus isolate NC14-02042014-3220 nonstructural protein 5 gene, partial cds141114117%0.099%KJ873161.1Select seq gb|KM851039.1|Zika virus strain SV0127/14 nonstructural protein 5 gene, partial cds137913797%0.099%KM851039.1Select seq gb|KM851038.1|Zika virus strain CPC-0740 nonstructural protein 5 gene, partial cds134213427%0.098%KM851038.1Select seq gb|KU556802.1|Zika virus isolate MEX/InDRE/14/2015 NS5 protein gene, partial cds133713377%0.099%KU556802.1Select seq gb|AF013415.1|Zika virus strain MR-766 NS5 protein (NS5) gene, partial cds1315131510%0.088%AF013415.1Select seq gb|KT200609.1|Zika virus isolate BR/949/15 NS5 gene, partial cds123612366%0.099%KT200609.1Select seq gb|KU232300.1|Zika virus isolate 067ZV_PEBR15 NS5 protein gene, partial cds123112316%0.099%KU232300.1Select seq gb|KU232290.1|Zika virus isolate 036ZV_PEBR15 NS5 protein gene, partial cds123112316%0.099%KU232290.1Select seq gb|KU232297.1|Zika virus isolate 049ZV_PEBR15 NS5 protein gene, partial cds122912296%0.099%KU232297.1Select seq gb|KU232294.1|Zika virus isolate 061ZV_PEBR15 NS5 protein gene, partial cds121612166%0.099%KU232294.1Select seq gb|KU232298.1|Zika virus isolate 050ZV_PEBR15 NS5 protein gene, partial cds121412146%0.099%KU232298.1Select seq gb|KU232292.1|Zika virus isolate 054ZV_PEBR15 NS5 protein gene, partial cds121312136%0.099%KU232292.1Select seq gb|KU232296.1|Zika virus isolate 045ZV_PEBR15 NS5 protein gene, partial cds121112116%0.099%KU232296.1Select seq gb|KU232293.1|Zika virus isolate 057ZV_PEBR15 NS5 protein gene, partial cds121112116%0.099%KU232293.1Select seq gb|KU232295.1|Zika virus isolate 068ZV_PEBR15 NS5 protein gene, partial cds120412046%0.099%KU232295.1Select seq gb|KU232288.1|Zika virus isolate 001ZV_PEBR15 NS5 protein gene, partial cds119111916%0.099%KU232288.1Select seq gb|KU232289.1|Zika virus isolate 020ZV_PEBR15 NS5 protein gene, partial cds118711876%0.099%KU232289.1Select seq gb|KU232299.1|Zika virus isolate 015ZV_PEBR15 NS5 protein gene, partial cds118411846%0.099%KU232299.1Select seq gb|KU232291.1|Zika virus isolate 051ZV_PEBR15 NS5 protein gene, partial cds118011806%0.099%KU232291.1Select seq gb|KU758878.1|Zika virus polyprotein gene, partial cds113311336%0.099%KU758878.1

LOCUS KU761564 10401 bp RNA linear VRL 26-FEB-2016 DEFINITION Zika virus isolate GDZ16001 polyprotein gene, complete cds. ACCESSION KU761564 VERSION KU761564.1 GI:1001231706 KEYWORDS . SOURCE Zika virus ORGANISM Zika virus Viruses; ssRNA viruses; ssRNA positive-strand viruses, no DNA stage; Flaviviridae; Flavivirus. REFERENCE 1 (bases 1 to 10401) AUTHORS Wu,D., Guan,D. and Zhang,H. TITLE Genomic analysis of Zika virus from two Chinese returning to Guangdong, China from Venezuela and Samoa February 2016 JOURNAL Unpublished REFERENCE 2 (bases 1 to 10401) AUTHORS Wu,D., Guan,D. and Zhang,H. TITLE Direct Submission JOURNAL Submitted (26-FEB-2016) Guangdong Provincial Center for Disease Control and Prevention, Institute of Microbiology, No. 160, Qunxian Road, Dashi town, Panyu District, Guangzhou City, Guangdong Province 511430, China COMMENT ##Assembly-Data-START## Sequencing Technology :: Sanger dideoxy sequencing ##Assembly-Data-END## FEATURES Location/Qualifiers source 1..10401 /organism="Zika virus" /mol_type="genomic RNA" /isolate="GDZ16001" /isolation_source="saliva" /host="Homo sapiens" /db_xref="taxon:64320" /country="China" /collection_date="12-Feb-2016" /note="type: Asian" CDS 49..10320 /codon_start=1 /product="polyprotein" /protein_id="AML82110.1" /db_xref="GI:1001231707" /translation="MKNPKKKSGGFRIVNMLKRGVARVSPFGGLKRLPAGLLLGHGPI RMVLAILAFLRFTAIKPSLGLINRWGSVGKKEAMEIIKKFKKDLAAMLRIINARKEKK RRGADTSVGIVGLLLTTAMAAEVTRRGSAYYMYLDRNDAGEAISFPTTLGMNKCYIQI MDLGHMCDATMSYECPMLDEGVEPDDVDCWCNTTSTWVVYGTCHHKKGEARRSRRAVT LPSHSTRKLQTRSQTWLESREYTKHLIRVENWIFRNPGFALAAAAIAWLLGSSTSQKV IYLVMILLIAPAYSIRCIGVSNRDFVEGMSGGTWVDVVLEHGGCVTVMAQDKPTVDIE LVTTTVSNMAEVRSYCYEASISDMASDSRCPTQGEAYLDKQSDTQYVCKRTLVDRGWG NGCGLFGKGSLVTCAKFACSKKMTGKSIQPENLEYRIMLSVHGSQHSGMIVNDTGHET DENRAKVEITPNSPRAEATLGGFGSLGLDCEPRTGLDFSDLYYLTMNNKHWLVHKEWF HDIPLPWHAGADTGTPHWNNKEALVEFKDAHAKRQTVVVLGSQEGAVHTALAGALEAE MDGAKGRLSSGHLKCRLKMDKLRLKGVSYSLCTAAFTFTKIPAETLHGTVTVEVQYAG TDGPCKVPAQMAVDMQTLTPVGRLITANPVITESTENSKMMLELDPPFGDSYIVIGVG EKKITHHWHRSGSTIGKAFEATVRGAKRMAVLGDTAWDFGSVGGALNSLGKGIHQIFG AAFKSLFGGMSWFSQILIGTLLMWLGLNTKNGSISLMCLALGGVLIFLSTAVSADVGC SVDFSKKETRCGTGVFVYNDVEAWRDRYKYHPDSPRRLAAAVKQAWEDGICGISSVSR MENIMWRSVEGELNAILEENGVQLTVVVGSVKNPMWRGPQRLPVPVNELPHGWKAWGK SYFVRAAKTNNSFVVDGDTLKECPLKHRAWNSFLVEDHGFGVFHTSVWLKVREDYSLE CDPAVIGTAVKGKEAVHSDLGYWIESEKNDTWRLKRAHLIEMKTCEWPKSHTLWTDGI EESDLIIPKSLAGPLSHHNTREGYRTQMKGPWHSEELEIRFEECPGTKVHVEETCGTR GPSLRSTTASGRVIEEWCCRECTMPPLSFRAKDGCWYGMEIRPRKEPESNLVRSMVTA GSTDHMDHFSLGVLVILLMVQEGLKKRMTTKIIISTSMAVLVAMILGGFSMSDLAKLA ILMGATFAEMNTGGDVAHLALIAAFKVRPALLVSFIFRANWTPRESMLLALASCLLQT AISALEGDLMVLINGFALAWLAVRAMVVPRTDNITLAILAALTPLARGTLLVAWRAGL ATCGGFMLLSLKGKGSVKKNLPFVMALGLTAVRLVDPINVVGLLLLTRSGKRSWPPSE VLTAVGLICALAGGFAKADIEMAGPMAAVGLLIVSYVVSGKSVDMYIERAGDITWEKD AEVTGNSPRLDVALDESGDFSLVEDDGPPMREIILKVVLMTICGMNPIAIPFAAGAWY VYVKTGKRSGALWDVPAPKEVKKGETTDGVYRVMTRRLLGSTQVGVGVMQEGVFHTMW HVTKGSALRSGEGRLDPYWGDVKQDLVSYCGPWKLDAAWDGHSEVQLLAVPPGERARN IQTLPGIFKTKDGDIGAVALDYPAGTSGSPILDKCGRVIGLYGNGVVIKNGSYVSAIT QGRREEETPVECFEPSMLKKKQLTVLDLHPGAGKTRRVLPEIVREAIKTRLRTVILAP TRVVAAEMEEALRGLPVRYMTTAVNVTHSGTEIVDLMCHATFTSRLLQPIRVPNYNLY IMDEAHFTDPSSIAARGYISTRVEMGEAAAIFMTATPPGTRDAFPDSNSPIMDTEVEV PERAWSSGFDWVTDHSGKTVWFVPSVRNGNEIAACLTKAGKRVIQLSRKTFETEFQKT KHQEWDFVVTTDISEMGANFKADRVIDSRRCLKPVILDGERVILAGPMPVTHASAAQR RGRIGRNPNKPGDEYLYGGGCAETDEDHAHWLEARMLLDNIYLQDGLIASLYRPEADK VAAIEGEFKLRTEQRKTFVELMKRGDLPVWLAYQVASAGITYTDRRWCFDGTTNNTIM EDSVPAEVWTRHGEKRVLKPRWMDARVCSDHAALKSFKEFAAGKRGAAFGVMEALGTL PGHMTERFQEAIDNLAVLMRAETGSRPYKAAAAQLPETLETIMLLGLLGTVSLGIFFV LMRNKGIGKMGFGMVTLGASAWLMWLSEIEPARIACVLIVVFLLLVVLIPEPEKQRSP QDNQMAIIIMVAVGLLGLITANELGWLERTKSDLSHLMGRREEGATIGFSMDIDLRPA SAWAIYAALTTFITPAVQHAVTTSYNNYSLMAMATQAGVLFGMGKGMPFYAWDFGVPL LMIGCYSQLTPLTLIVAIILLVAHYMYLIPGLQAAAARAAQKRTAAGIMKNPVVDGIV VTDIDTMTIDPQVEKKMGQVLLIAVAVSSAILSRTAWGWGEAGALITAATSTLWEGSP NKYWNSSTATSLCNIFRGSYLAGASLIYTVTRNAGLVKRRGGGTGETLGEKWKARLNQ MSALEFYSYKKSGITEVCREEARRALKDGVATGGHAVSRGSAKLRWLVERGYLQPYGK VIDLGCGRGGWSYYAATIRKVQEVKGYTKGGPGHEEPVLVQSYGWNIVRLKSGVDVFH MAAEPCDTLLCDIGESSSSPEVEEARTLRVLSMVGDWLEKRPGAFCIKVLCPYTSTMM ETLERLQRRYGGGLVRVPLSRNSTHEMYWVSGAKSNIIKSVSTTSQLLLGRMDGPRRP VKYEEDVNLGSGTRAVASCAEAPNMKIIGNRIERIRSEHAETWFFDENHPYRTWAYHG SYEAPTQGSASSLINGVVRLLSKPWDVVTGVTGIAMTDTTPYGQQRVFKEKVDTRVPD PQEGTRQVMSMVSSWLWKELGKHKRPRVCTKEEFINKVRSNAALGAIFEEEKEWKTAV EAVNDPRFWALVDKEREHHLRGECQSCVYNMMGKREKKQGEFGKAKGSRAIWYMWLGA RFLEFEALGFLNEDHWMGRENSGGGVEGLGLQRLGYVLEEMSRIPGGRMYADDTAGWD TRISRFDLENEALITNQMEKGHRALALAIIKYTYQNKVVKVLRPAEKGKTVMDIISRQ DQRGSGQVVTYALNTFTNLVVQLIRNMEAEEVLEMQDLWLLRRSEKVTNWLQSNGWDR LKRMAVSGDDCVVKPIDDRFAHALRFLNDMGKVRKDTQEWKPSTGWDNWEEVPFCSHH FNKLHLKDGRSIVVPCRHQDELIGRARVSPGAGWSIRETACLAKSYAQMWQLLYFHRR DLRLMANAICSSVPVDWVPTGRTTWSIHGKGEWMTTEDMLVVWNRVWIEENDHMEDKT PVTKWTDIPYLGKREDLWCGSLIGHRPRTTWAENIKNTVNMVRRIIGDEEKYMDYLST QVRYLGEEGSTPGVL" ORIGIN 1 cagtatcaac aggttttatt ttggatttgg aaacgagagt ttctggtcat gaaaaaccca 61 aaaaagaaat ccggaggatt ccggattgtc aatatgctaa aacgcggagt agcccgtgtg 121 agcccctttg ggggcttgaa gaggctgcca gccggacttc tgctgggtca tgggcccatc 181 aggatggtct tggcgattct agccttcttg agattcacgg caatcaagcc atcactgggt 241 ctcatcaata gatggggttc agtggggaaa aaagaggcta tggaaataat aaagaagttc 301 aagaaagatc tggctgccat gctgagaata atcaatgcta ggaaggagaa gaagagacga 361 ggcgcagata ctagtgtcgg aattgttggc ctcctgctga ccacagctat ggcagcggag 421 gtcactagac gtgggagtgc atactatatg tacttggaca gaaacgatgc tggggaggcc 481 atatcttttc caaccacatt ggggatgaat aagtgttata tacagatcat ggatcttgga 541 cacatgtgtg atgccaccat gagctatgaa tgccctatgc tggatgaggg ggtggaacca 601 gatgacgtcg attgttggtg caacacgacg tcaacttggg ttgtgtacgg aacctgccat 661 cacaaaaaag gtgaagcacg gagatctaga agagctgtga cgctcccttc ccattccact 721 aggaagctgc aaacgcggtc gcaaacctgg ttggaatcaa gagaatacac aaagcacttg 781 attagagtcg aaaattggat attcaggaac cctggcttcg cgttagcagc agctgctatc 841 gcttggcttt tgggaagctc aacgagccaa aaagtcatat acttggtcat gatactgctg 901 attgccccgg catacagcat caggtgcata ggagtcagca atagggactt tgtggaaggt 961 atgtcaggtg ggacttgggt tgatgttgtc ttggaacatg gaggttgtgt caccgtaatg 1021 gcacaggaca aaccgactgt cgacatagag ctggttacaa caacagtcag caacatggcg 1081 gaggtaagat cctactgcta tgaggcatca atatcagaca tggcttcgga cagccgctgc 1141 ccaacacaag gtgaagccta ccttgacaag caatcagaca ctcaatatgt ctgcaaaaga 1201 acgttagtgg acagaggctg gggaaatgga tgtggacttt ttggcaaagg gagcctggtg 1261 acatgcgcta agtttgcatg ctccaagaaa atgaccggga aaagcatcca gccagagaat 1321 ctggagtacc ggataatgct gtcagttcat ggctcccagc acagtgggat gatcgttaat 1381 gacacaggac atgaaactga tgagaataga gcgaaagttg agataacgcc caattcacca 1441 agagccgaag ccaccctggg gggttttgga agcctaggac ttgattgtga accgaggaca 1501 ggccttgact tttcagattt gtattacttg actatgaata acaagcactg gttggttcac 1561 aaggagtggt tccacgacat tccattacct tggcacgctg gggcagacac cggaactcca 1621 cactggaaca acaaagaagc actggtagag ttcaaggacg cacatgccaa aaggcaaact 1681 gtcgtggttc tagggagtca agaaggagca gttcacacgg cccttgctgg agctctggag 1741 gctgagatgg atggagcaaa gggaaggctg tcctctggcc acttgaaatg tcgcctgaaa 1801 atggataaac ttagattgaa gggcgtgtca tactccttgt gtactgcagc gttcacattc 1861 accaagatcc cggctgaaac actgcacggg acagtcacag tggaggtaca gtacgcaggg 1921 acagatggac cttgcaaggt tccagctcag atggcggtgg acatgcaaac tctgacccca 1981 gttgggaggt tgataaccgc taaccccgta atcactgaaa gcactgagaa ctctaagatg 2041 atgctggaac ttgatccacc atttggggac tcttacattg tcataggagt cggggagaag 2101 aagatcaccc accactggca caggagtggc agcaccattg gaaaagcatt tgaagccact 2161 gtgagaggtg ccaagagaat ggcagtcttg ggagacacag cctgggactt tggatcagtt 2221 ggaggcgctc tcaactcatt gggcaagggc atccatcaaa tttttggagc agctttcaaa 2281 tcattgtttg gaggaatgtc ctggttctca caaattctca ttggaacgtt gctgatgtgg 2341 ttgggtctga acacaaagaa tggatctatt tcccttatgt gcttggcctt agggggagtg 2401 ttgatcttct tatccacagc cgtctctgct gatgtggggt gctcggtgga cttctcaaag 2461 aaggagacga gatgcggtac aggggtgttt gtctataacg acgttgaagc ctggagggac 2521 aggtacaagt accatcctga ctccccccgt agattggcag cagcagtcaa gcaagcctgg 2581 gaagatggta tctgcgggat ctcctctgtt tcaagaatgg aaaacatcat gtggagatca 2641 gtagaagggg agctcaacgc aatcctggaa gagaatggag ttcaactgac ggtcgttgtg 2701 ggatctgtaa aaaaccccat gtggagaggt ccacagagat tgcccgtgcc tgtgaacgag 2761 ctgccccacg gctggaaggc ttgggggaaa tcgtacttcg tcagagcagc aaagacaaat 2821 aacagctttg tcgtggatgg tgacacactg aaggaatgcc cactcaaaca tagagcatgg 2881 aacagctttc ttgtggagga tcatgggttc ggggtatttc acactagtgt ctggctcaag 2941 gttagagaag actattcatt agagtgtgat ccagccgtta ttggaacagc tgttaaggga 3001 aaggaggctg tacacagtga tctaggctac tggattgaga gtgagaagaa tgacacatgg 3061 aggctgaaga gggcccatct gatcgagatg aaaacatgtg aatggccaaa gtcccacaca 3121 ttgtggacag atggaataga agagagtgat ctgatcatac ccaagtcttt agctgggcca 3181 ctcagccatc acaataccag agagggctac aggacccaaa tgaaagggcc atggcacagt 3241 gaggagcttg aaattcggtt tgaggaatgc ccaggcacta aggtccacgt ggaggaaaca 3301 tgtggaacaa gaggaccatc tctgagatca accactgcaa gcggaagggt gatcgaggaa 3361 tggtgctgca gggagtgcac aatgccccca ctgtcgttcc gggctaaaga tggctgttgg 3421 tatggaatgg agataaggcc caggaaagaa ccagaaagca acttagtaag gtcaatggtg 3481 actgcaggat caactgatca catggaccac ttctcccttg gagtgcttgt gatcctgctc 3541 atggtgcagg aagggctgaa gaagagaatg accacaaaga tcatcataag cacatcaatg 3601 gcagtgctgg tagctatgat cctgggagga ttttcaatga gtgacctggc taagcttgca 3661 attttgatgg gtgccacctt cgcggaaatg aacactggag gagatgtagc tcatctggcg 3721 ctgatagcgg cattcaaagt cagaccagcg ttgctggtat ctttcatctt cagagctaat 3781 tggacacccc gtgaaagcat gctgctggcc ttggcctcgt gtcttttgca aactgcgatc 3841 tccgccttgg aaggcgacct gatggttctc atcaatggtt ttgctttggc ctggttggca 3901 gtacgagcga tggttgttcc acgcactgat aacatcacct tagcaatcct ggctgctctg 3961 acaccactgg cccggggcac actgcttgtg gcgtggagag caggccttgc tacttgcggg 4021 gggtttatgc tcctctctct gaagggaaaa ggcagtgtga agaagaactt accatttgtc 4081 atggccctgg gactaaccgc tgtgaggctg gtcgacccca tcaacgtggt gggactgctg 4141 ttgctcacaa ggagtgggaa gcggagctgg ccccctagcg aagtactcac agctgttggc 4201 ctgatatgcg cattggctgg agggttcgcc aaggcagata tagagatggc tgggcccatg 4261 gccgcggtcg gtctgctaat tgtcagttac gtggtctcag gaaagagtgt ggacatgtac 4321 attgaaagag caggtgacat cacatgggaa aaagatgcgg aagtcactgg aaacagtccc 4381 cggctcgatg tggcgctaga tgagagtggt gatttctccc tggtggagga tgacggtccc 4441 cccatgagag agatcatact caaggtggtc ctgatgacca tctgtggcat gaacccaata 4501 gccataccct ttgcagctgg agcgtggtac gtatacgtga agactggaaa aaggagtggt 4561 gctctatggg atgtgcctgc tcccaaggaa gtaaaaaagg gggagaccac agatggagtg 4621 tacagagtaa tgactcgcag actgctaggt tcaacacaag ttggagtggg agttatgcaa 4681 gagggggtct ttcacactat gtggcacgtc acaaaaggat ccgcgctgag aagcggtgaa 4741 gggagacttg atccatactg gggagatgtc aagcaggatc tggtgtcata ctgtggtcca 4801 tggaagctag atgccgcctg ggacgggcac agcgaggtgc agctcttggc cgtgcccccc 4861 ggagagagag cgaggaacat ccagactctg cccggaatat ttaagacaaa ggatggggac 4921 attggagcgg ttgcgctgga ttacccagca ggaacttcag gatctccaat cctagacaag 4981 tgtgggagag tgataggact ttatggcaat ggggtcgtga tcaaaaatgg gagttatgtt 5041 agtgccatca cccaagggag gagggaggaa gagactcctg ttgagtgctt cgagccttcg 5101 atgctgaaga agaagcagct aactgtctta gacttgcatc ctggagctgg gaaaaccagg 5161 agagttcttc ctgaaatagt ccgtgaagcc ataaaaacaa gactccgtac tgtgatctta 5221 gctccaacca gggttgtcgc tgctgaaatg gaggaggccc ttagagggct tccagtgcgt 5281 tatatgacaa cagcagtcaa tgtcacccac tctggaacag aaatcgtcga cttaatgtgc 5341 catgccacct tcacttcacg tctactacag ccaattagag tccccaacta taatctgtat 5401 attatggatg aggcccactt cacagatccc tcaagtatag cagcaagagg atacatttca 5461 acaagggttg agatgggcga ggcggctgcc atcttcatga ccgccacgcc accaggaacc 5521 cgtgacgcat ttccggactc caactcacca attatggaca ccgaagtgga agtcccagag 5581 agagcctgga gctcaggctt tgattgggtg acggatcatt ctggaaaaac agtttggttt 5641 gttccaagcg tgaggaacgg caatgagatc gcagcttgtc tgacaaaggc tggaaaacgg 5701 gtcatacagc tcagcagaaa gacttttgag acagagttcc agaaaacaaa acatcaagag 5761 tgggactttg tcgtgacaac tgacatttca gagatgggcg ccaactttaa agctgaccgt 5821 gtcatagatt ccaggagatg cctaaagccg gtcatacttg atggcgagag agtcattctg 5881 gctggaccca tgcctgtcac acatgccagc gctgcccaga ggagggggcg cataggcagg 5941 aatcccaaca aacctggaga tgagtatctg tatggaggtg ggtgcgcaga gactgacgaa 6001 gaccatgcac actggcttga agcaagaatg ctccttgaca atatttacct ccaagatggc 6061 ctcatagcct cgctctatcg acctgaggcc gacaaagtag cagccattga gggagagttc 6121 aagcttagga cggagcaaag gaagaccttt gtggaactca tgaaaagagg agatcttcct 6181 gtttggctgg cctatcaggt tgcatctgcc ggaataacct acacagatag aagatggtgc 6241 tttgatggca cgaccaacaa caccataatg gaagacagtg tgccggcaga ggtgtggacc 6301 agacacggag agaaaagagt gctcaaaccg aggtggatgg acgccagagt ttgttcagat 6361 catgcggccc tgaagtcatt caaggagttt gccgctggga aaagaggagc ggcttttgga 6421 gtgatggaag ccctgggaac actgccagga cacatgacag agagattcca ggaagccatt 6481 gacaacctcg ctgtgctcat gcgggcagag actggaagca ggccttacaa agccgcggca 6541 gcccaattgc cggagaccct agagaccatt atgcttttgg ggttgctggg aacagtctcg 6601 ctgggaatct tcttcgtctt gatgaggaac aagggcatag ggaagatggg ctttggaatg 6661 gtgactcttg gggccagcgc atggctcatg tggctctcgg aaattgagcc agccagaatt 6721 gcatgtgtcc tcattgttgt gttcctattg ctggtggtgc tcatacctga gccagaaaag 6781 caaagatctc cccaggacaa ccaaatggca atcatcatca tggtagcagt aggtcttctg 6841 ggcttgatta ccgccaatga actcggatgg ttggagagaa caaagagtga cctaagccat 6901 ctaatgggaa ggagagagga gggggcaacc ataggattct caatggacat tgacctgcgg 6961 ccagcctcag cttgggccat ctatgctgcc ttgacaactt tcattacccc agccgtccaa 7021 catgcagtga ccacctcata caacaactac tccttaatgg cgatggccac gcaagctgga 7081 gtgttgtttg gtatgggcaa agggatgcca ttctacgcat gggactttgg agtcccgctg 7141 ctaatgatag gctgctactc acaattaaca cccctgaccc taatagtggc catcattttg 7201 ctcgtggcgc actacatgta cttgatccca gggctgcagg cagcagctgc gcgtgctgcc 7261 cagaagagaa cggcagctgg catcatgaag aaccctgttg tggatggaat agtggtgact 7321 gacattgaca caatgacaat tgacccccaa gtggagaaaa agatgggaca ggtgctactc 7381 atagcagtag ccgtctccag cgccatactg tcgcggaccg cctgggggtg gggggaggct 7441 ggggccctga tcacagccgc aacttccact ttgtgggaag gctctccgaa caagtactgg 7501 aactcctcta cagccacttc actgtgtaac atttttaggg gaagttactt ggctggagct 7561 tctctaatct acacagtaac aagaaacgct ggcttggtca agagacgtgg gggtggaaca 7621 ggagagaccc tgggagagaa atggaaggcc cgcttgaacc agatgtcggc cctggagttc 7681 tactcctaca aaaagtcagg catcaccgag gtgtgcagag aagaggcccg ccgcgccctc 7741 aaggacggtg tggcaacggg aggccatgct gtgtcccgag gaagtgcaaa gctgagatgg 7801 ttggtggagc ggggatacct gcagccctat ggaaaggtca ttgatcttgg atgtggcaga 7861 gggggctgga gttactacgc cgccaccatc cgcaaagttc aagaagtgaa aggatacaca 7921 aaaggaggcc ctggtcatga agaacccgtg ttggtgcaaa gctatgggtg gaacatagtc 7981 cgtcttaaga gtggggtgga cgtctttcat atggcggctg agccgtgtga cacgttgctg 8041 tgtgacatag gtgagtcatc atctagtcct gaagtggaag aagcacggac gctcagagtc 8101 ctctccatgg tgggggattg gcttgaaaaa agaccaggag ccttttgcat aaaagtgttg 8161 tgcccataca ccagcactat gatggaaacc ctggagcgac tgcagcgtag gtatggggga 8221 ggactggtca gagtgccact ctcccgcaac tctacacatg agatgtactg ggtctctgga 8281 gcgaaaagca acatcataaa aagtgtgtcc accacgagcc agctcctctt ggggcgcatg 8341 gacgggccta ggaggccagt gaaatatgag gaggatgtga atctcggctc tggcacgcgg 8401 gctgtggcaa gctgcgctga agctcccaac atgaagatca ttggtaaccg cattgaaagg 8461 atccgcagtg agcacgcgga aacgtggttc tttgacgaga accacccata taggacatgg 8521 gcttaccatg gaagctatga ggcccccaca caagggtcag cgtcctctct aataaacggg 8581 gttgtcaggc tcctgtcaaa accctgggat gtggtgactg gagtcacagg aatagccatg 8641 accgacacca caccgtatgg tcagcaaaga gttttcaagg aaaaagtgga cactagggtg 8701 ccagaccccc aagaaggcac tcgtcaggtt atgagcatgg tctcttcctg gttgtggaaa 8761 gagctaggca aacacaaacg gccacgagtc tgtaccaaag aagagttcat caacaaggtt 8821 cgtagcaatg cagcattagg ggcaatattt gaagaggaaa aagagtggaa gactgcagtg 8881 gaagctgtga acgatccaag gttctgggct ctagtggaca aggaaagaga gcaccacctg 8941 agaggagagt gccagagttg tgtgtacaac atgatgggaa aaagagaaaa gaaacaaggg 9001 gaatttggaa aggccaaggg cagccgcgcc atctggtata tgtggctggg ggctagattt 9061 ctagagttcg aagcccttgg attcttgaac gaggatcact ggatggggag agagaactca 9121 ggaggtggtg ttgaagggct gggattacaa agactcggat atgtcctaga agagatgagt 9181 cgtataccag gaggaaggat gtatgcagat gacactgctg gctgggacac ccgcattagc 9241 aggtttgatc tggagaatga agctctaatc accaaccaaa tggagaaagg gcacagggcc 9301 ttggcattgg ccataatcaa gtacacatac caaaacaaag tggtaaaggt ccttagacca 9361 gctgaaaaag ggaaaacagt tatggacatt atttcgagac aagaccaaag ggggagcgga 9421 caagttgtca cttacgctct taacacattt accaacctag tggtgcaact cattcggaat 9481 atggaggctg aggaagttct agagatgcaa gacttgtggc tgctgcggag gtcagagaaa 9541 gtgaccaact ggttgcagag caacggatgg gataggctca aacgaatggc agtcagtgga 9601 gatgattgcg ttgtgaagcc aattgatgat aggtttgcac atgccctcag gttcttgaat 9661 gatatgggaa aagttaggaa ggacacacaa gagtggaaac cctcaactgg atgggacaac 9721 tgggaagaag ttccgttttg ctcccaccat ttcaacaagc tccatctcaa ggacgggagg 9781 tccattgtgg ttccctgccg ccaccaagat gaactgattg gccgggcccg cgtctctcca 9841 ggggcgggat ggagcatccg ggagactgct tgcctagcaa aatcatatgc gcaaatgtgg 9901 cagctccttt atttccacag aagggacctc cgactgatgg ccaatgccat ttgttcatct 9961 gtgccagttg actgggttcc aactgggaga actacctggt caatccatgg aaagggagaa 10021 tggatgacca ctgaagacat gcttgtggtg tggaacagag tgtggattga ggagaacgac 10081 cacatggaag acaagacccc agttacgaaa tggacagaca ttccctattt gggaaaaagg 10141 gaagacttgt ggtgtggatc tctcataggg cacagaccgc gcaccacctg ggctgagaac 10201 attaaaaaca cagtcaacat ggtgcgcagg atcataggtg atgaagaaaa gtacatggat 10261 tacctatcca cccaagttcg ctacttgggt gaagaagggt ctacacctgg agtgctgtaa 10321 gcaccaatct taatgttgtc aggcctgcta gtcagccaca gcttggggaa agctgtgcag 10381 cctgtgaccc ccccaggaga a

Sequences producing significant alignments:Select:AllNone Selected:0 AlignmentsDownloadGenBankGraphicsDistance tree of resultsShow/hide columns of the table presenting sequences producing significant alignmentsSequences producing significant alignments:Select for downloading or viewing reportsDescriptionMax scoreTotal scoreQuery coverE valueIdentAccessionSelect seq gb|KU744693.1|Zika virus isolate VE_Ganxian, complete genome1852518525100%0.0100%KU744693.1Select seq gb|KU509998.1|Zika virus strain Haiti/1225/2014, complete genome1825818258100%0.099%KU509998.1Select seq gb|KU321639.1|Zika virus strain ZikaSPH2015, complete genome1823618236100%0.099%KU321639.1Select seq gb|KJ776791.1|Zika virus strain H/PF/2013 polyprotein gene, complete cds1820018200100%0.099%KJ776791.1Select seq gb|KU707826.1|Zika virus isolate SSABR1, complete genome1818218182100%0.099%KU707826.1Select seq gb|KU365779.1|Zika virus strain BeH819966 polyprotein gene, complete cds1818218182100%0.099%KU365779.1Select seq gb|KU365780.1|Zika virus strain BeH815744 polyprotein gene, complete cds1816818168100%0.099%KU365780.1Select seq gb|KU365777.1|Zika virus strain BeH818995 polyprotein gene, complete cds1816418164100%0.099%KU365777.1Select seq gb|KU740184.1|Zika virus isolate GD01 polyprotein gene, complete cds1815918159100%0.099%KU740184.1Select seq gb|KU501217.1|Zika virus strain 8375 polyprotein gene, complete cds1815918159100%0.099%KU501217.1Select seq gb|KU527068.1|Zika virus strain Natal RGN, complete genome1815518155100%0.099%KU527068.1Select seq gb|KU647676.1|Zika virus strain MRS_OPY_Martinique_PaRi_2015 polyprotein gene, complete cds1815518155100%0.099%KU647676.1Select seq gb|KU501216.1|Zika virus strain 103344 polyprotein gene, complete cds1815518155100%0.099%KU501216.1Select seq gb|KU365778.1|Zika virus strain BeH819015 polyprotein gene, complete cds1815018150100%0.099%KU365778.1Select seq gb|KU312312.1|Zika virus isolate Z1106033 polyprotein gene, complete cds1815018150100%0.099%KU312312.1Select seq gb|KU497555.1|Zika virus isolate Brazil-ZKV2015, complete genome181461814699%0.099%KU497555.1Select seq gb|KU501215.1|Zika virus strain PRVABC59, complete genome1814118141100%0.099%KU501215.1Select seq gb|KU681081.3|Zika virus isolate Zika virus/H.sapiens-tc/THA/2014/SV0127- 14, complete genome1786117861100%0.099%KU681081.3Select seq gb|JN860885.1|Zika virus isolate FSS13025 polyprotein gene, partial cds175671756799%0.098%JN860885.1Select seq gb|KF993678.1|Zika virus strain PLCal_ZV from Canada polyprotein gene, partial cds175171751798%0.098%KF993678.1Select seq gb|EU545988.1|Zika virus polyprotein gene, complete cds1740517405100%0.098%EU545988.1Select seq gb|KU681082.3|Zika virus isolate Zika virus/H.sapiens-tc/PHL/2012/CPC-0740, complete genome1724817248100%0.097%KU681082.3Select seq gb|HQ234499.1|Zika virus isolate P6-740 polyprotein gene, partial cds162801628099%0.095%HQ234499.1Select seq gb|KU720415.1|Zika virus strain MR 766 polyprotein gene, complete cds1316413164100%0.088%KU720415.1Select seq gb|HQ234498.1|Zika virus isolate MR_766 polyprotein gene, partial cds131581315899%0.088%HQ234498.1Select seq gb|KF268949.1|Zika virus isolate ARB15076 polyprotein gene, complete cds1315313153100%0.088%KF268949.1Select seq gb|KF268948.1|Zika virus isolate ARB13565 polyprotein gene, complete cds1315313153100%0.088%KF268948.1Select seq gb|KF383115.1|Zika virus strain ArB1362 polyprotein gene, complete cds1314913149100%0.088%KF383115.1Select seq gb|KF268950.1|Zika virus isolate ARB7701 polyprotein gene, complete cds1314613146100%0.088%KF268950.1Select seq dbj|LC002520.1|Zika virus genomic RNA, complete genome, strain: MR766-NIID1314213142100%0.088%LC002520.1Select seq gb|KF383119.1|Zika virus strain ArD158084 polyprotein gene, complete cds1313713137100%0.088%KF383119.1Select seq gb|DQ859059.1|Zika virus strain MR 766 polyprotein gene, complete cds1313113131100%0.088%DQ859059.1Select seq gb|AY632535.2|Zika virus strain MR 766, complete genome1308213082100%0.088%AY632535.2Select seq gb|KF383116.1|Zika virus strain ArD7117 polyprotein gene, complete cds1308113081100%0.088%KF383116.1Select seq gb|HQ234501.1|Zika virus isolate ArD_41519 polyprotein gene, partial cds130611306199%0.088%HQ234501.1Select seq gb|KF383117.1|Zika virus strain ArD128000 polyprotein gene, complete cds1301913019100%0.088%KF383117.1Select seq gb|HQ234500.1|Zika virus isolate IbH_30656 polyprotein gene, partial cds129851298599%0.088%HQ234500.1Select seq gb|KF383118.1|Zika virus strain ArD157995 polyprotein gene, complete cds1283712905100%0.088%KF383118.1Select seq gb|KF383121.1|Zika virus strain ArD158095 polyprotein gene, partial cds127381273897%0.088%KF383121.1Select seq gb|KF383120.1|Zika virus strain ArD142623 nonfunctional polyprotein gene, partial sequence107181071897%0.084%KF383120.1Select seq gb|KU312314.1|Zika virus isolate Z1106031 polyprotein gene, partial cds4908490827%0.099%KU312314.1Select seq gb|KU312313.1|Zika virus isolate Z1106032 polyprotein gene, partial cds4881488127%0.099%KU312313.1Select seq gb|KU646828.1|Zika virus isolate Si322 polyprotein gene, partial cds4560456025%0.099%KU646828.1Select seq gb|KU646827.1|Zika virus isolate Si323 polyprotein gene, partial cds4551455125%0.099%KU646827.1Select seq gb|KU312315.1|Zika virus isolate Z1106027 polyprotein gene, partial cds3377337718%0.099%KU312315.1Select seq gb|KU740199.1|Zika virus isolate VE_Ganxian2016 polyprotein gene, partial cds3256325617%0.099%KU740199.1Select seq gb|DQ859064.1|Spondweni virus strain SM-6 V-1 polyprotein gene, complete cds2854412595%0.071%DQ859064.1Select seq gb|KJ634273.1|Zika virus strain CK-ISL 2014 E protein (E) gene, partial cds2639263914%0.099%KJ634273.1Select seq gb|KU686218.1|Zika virus isolate MEX/InDRE/14/2015 polyprotein gene, partial cds2039203911%0.098%KU686218.1Select seq gb|KU179098.1|Zika virus isolate JMB-185 nonstructural protein 5 gene, partial cds1994199411%0.099%KU179098.1Select seq gb|KM078936.1|Zika virus strain CHI1410214 NS5 protein gene, partial cds173717379%0.099%KM078936.1Select seq gb|KM078961.1|Zika virus strain CHI2612114 NS5 protein gene, partial cds173617369%0.099%KM078961.1Select seq gb|KM078930.1|Zika virus strain CHI2283714 NS5 protein gene, partial cds173417349%0.099%KM078930.1Select seq gb|KM078971.1|Zika virus strain CHI2613014 NS5 protein gene, partial cds173017309%0.099%KM078971.1Select seq gb|KM078970.1|Zika virus strain CHI2490414 NS5 protein gene, partial cds173017309%0.099%KM078970.1Select seq gb|KM078933.1|Zika virus strain CHI1058514 NS5 protein gene, partial cds173017309%0.099%KM078933.1Select seq gb|KM078929.1|Zika virus strain CHI1805214 NS5 protein gene, partial cds172817289%0.099%KM078929.1Select seq gb|KJ873160.1|Zika virus isolate NC14-03042014-3481 nonstructural protein 5 gene, partial cds158815888%0.099%KJ873160.1Select seq gb|KJ873161.1|Zika virus isolate NC14-02042014-3220 nonstructural protein 5 gene, partial cds140614067%0.099%KJ873161.1Select seq gb|KM851039.1|Zika virus strain SV0127/14 nonstructural protein 5 gene, partial cds137013707%0.098%KM851039.1Select seq gb|KM851038.1|Zika virus strain CPC-0740 nonstructural protein 5 gene, partial cds134213427%0.098%KM851038.1Select seq gb|KU556802.1|Zika virus isolate MEX/InDRE/14/2015 NS5 protein gene, partial cds132413247%0.099%KU556802.1Select seq gb|AF013415.1|Zika virus strain MR-766 NS5 protein (NS5) gene, partial cds1310131010%0.088%AF013415.1Select seq gb|KU232300.1|Zika virus isolate 067ZV_PEBR15 NS5 protein gene, partial cds121612166%0.099%KU232300.1Select seq gb|KU232290.1|Zika virus isolate 036ZV_PEBR15 NS5 protein gene, partial cds120712076%0.099%KU232290.1Select seq gb|KU232297.1|Zika virus isolate 049ZV_PEBR15 NS5 protein gene, partial cds120512056%0.099%KU232297.1Select seq gb|KT200609.1|Zika virus isolate BR/949/15 NS5 gene, partial cds120412046%0.098%KT200609.1Select seq gb|KU232294.1|Zika virus isolate 061ZV_PEBR15 NS5 protein gene, partial cds119811986%0.099%KU232294.1Select seq gb|KU232292.1|Zika virus isolate 054ZV_PEBR15 NS5 protein gene, partial cds119511956%0.099%KU232292.1Select seq gb|KU232298.1|Zika virus isolate 050ZV_PEBR15 NS5 protein gene, partial cds119111916%0.099%KU232298.1Select seq gb|KU232293.1|Zika virus isolate 057ZV_PEBR15 NS5 protein gene, partial cds118911896%0.099%KU232293.1Select seq gb|KU232296.1|Zika virus isolate 045ZV_PEBR15 NS5 protein gene, partial cds118711876%0.099%KU232296.1Select seq gb|KU232295.1|Zika virus isolate 068ZV_PEBR15 NS5 protein gene, partial cds118411846%0.099%KU232295.1Select seq gb|KU232288.1|Zika virus isolate 001ZV_PEBR15 NS5 protein gene, partial cds117311736%0.099%KU232288.1Select seq gb|KU232289.1|Zika virus isolate 020ZV_PEBR15 NS5 protein gene, partial cds116911696%0.099%KU232289.1Select seq gb|KU232299.1|Zika virus isolate 015ZV_PEBR15 NS5 protein gene, partial cds116611666%0.099%KU232299.1Select seq gb|KU232291.1|Zika virus isolate 051ZV_PEBR15 NS5 protein gene, partial cds116211626%0.099%KU232291.1Select seq gb|KU758878.1|Zika virus polyprotein gene, partial cds113011306%0.098%KU758878.1

Sequences producing significant alignments:Select:AllNone Selected:0 AlignmentsDownloadGenBankGraphicsDistance tree of resultsShow/hide columns of the table presenting sequences producing significant alignmentsSequences producing significant alignments:Select for downloading or viewing reportsDescriptionMax scoreTotal scoreQuery coverE valueIdentAccessionSelect seq gb|KU744693.1|Zika virus isolate VE_Ganxian, complete genome1852518525100%0.0100%KU744693.1Select seq gb|KU509998.1|Zika virus strain Haiti/1225/2014, complete genome1825818258100%0.099%KU509998.1Select seq gb|KU321639.1|Zika virus strain ZikaSPH2015, complete genome1823618236100%0.099%KU321639.1Select seq gb|KJ776791.1|Zika virus strain H/PF/2013 polyprotein gene, complete cds1820018200100%0.099%KJ776791.1Select seq gb|KU707826.1|Zika virus isolate SSABR1, complete genome1818218182100%0.099%KU707826.1Select seq gb|KU365779.1|Zika virus strain BeH819966 polyprotein gene, complete cds1818218182100%0.099%KU365779.1Select seq gb|KU365780.1|Zika virus strain BeH815744 polyprotein gene, complete cds1816818168100%0.099%KU365780.1Select seq gb|KU365777.1|Zika virus strain BeH818995 polyprotein gene, complete cds1816418164100%0.099%KU365777.1Select seq gb|KU740184.1|Zika virus isolate GD01 polyprotein gene, complete cds1815918159100%0.099%KU740184.1Select seq gb|KU501217.1|Zika virus strain 8375 polyprotein gene, complete cds1815918159100%0.099%KU501217.1Select seq gb|KU527068.1|Zika virus strain Natal RGN, complete genome1815518155100%0.099%KU527068.1Select seq gb|KU647676.1|Zika virus strain MRS_OPY_Martinique_PaRi_2015 polyprotein gene, complete cds1815518155100%0.099%KU647676.1Select seq gb|KU501216.1|Zika virus strain 103344 polyprotein gene, complete cds1815518155100%0.099%KU501216.1Select seq gb|KU365778.1|Zika virus strain BeH819015 polyprotein gene, complete cds1815018150100%0.099%KU365778.1Select seq gb|KU312312.1|Zika virus isolate Z1106033 polyprotein gene, complete cds1815018150100%0.099%KU312312.1Select seq gb|KU497555.1|Zika virus isolate Brazil-ZKV2015, complete genome181461814699%0.099%KU497555.1Select seq gb|KU501215.1|Zika virus strain PRVABC59, complete genome1814118141100%0.099%KU501215.1Select seq gb|KU681081.3|Zika virus isolate Zika virus/H.sapiens-tc/THA/2014/SV0127- 14, complete genome1786117861100%0.099%KU681081.3Select seq gb|JN860885.1|Zika virus isolate FSS13025 polyprotein gene, partial cds175671756799%0.098%JN860885.1Select seq gb|KF993678.1|Zika virus strain PLCal_ZV from Canada polyprotein gene, partial cds175171751798%0.098%KF993678.1Select seq gb|EU545988.1|Zika virus polyprotein gene, complete cds1740517405100%0.098%EU545988.1Select seq gb|KU681082.3|Zika virus isolate Zika virus/H.sapiens-tc/PHL/2012/CPC-0740, complete genome1724817248100%0.097%KU681082.3Select seq gb|HQ234499.1|Zika virus isolate P6-740 polyprotein gene, partial cds162801628099%0.095%HQ234499.1

LOCUS KU744693 10676 bp RNA linear VRL 23-FEB-2016 DEFINITION Zika virus isolate VE_Ganxian, complete genome. ACCESSION KU744693 VERSION KU744693.1 GI:998961613 KEYWORDS . SOURCE Zika virus ORGANISM Zika virus Viruses; ssRNA viruses; ssRNA positive-strand viruses, no DNA stage; Flaviviridae; Flavivirus. REFERENCE 1 (bases 1 to 10676) AUTHORS Wu,W., Liu,L., Zhao,X., Nie,K., Li,J., Qu,J., Zhang,S., Liang,M. and Li,D. TITLE Zika virus from an imported Chinese case, February 2016 JOURNAL Unpublished REFERENCE 2 (bases 1 to 10676) AUTHORS Wu,W., Liu,L., Zhao,X., Nie,K., Li,J., Qu,J., Zhang,S., Liang,M. and Li,D. TITLE Direct Submission JOURNAL Submitted (22-FEB-2016) Department of Viral Hemorrhagic Fever, National Institute for Viral Diseases Control and Prevention, Changbai Road 155, Beijing, Beijing 102206, China COMMENT ##Assembly-Data-START## Assembly Method :: CLC genomics workbench v. 8.5.1 Sequencing Technology :: IonTorrent ##Assembly-Data-END## FEATURES Location/Qualifiers source 1..10676 /organism="Zika virus" /mol_type="genomic RNA" /isolate="VE_Ganxian" /isolation_source="serum" /host="Homo sapiens" /db_xref="taxon:64320" /country="China" /collection_date="06-Feb-2016" /note="imported from Venezuela; type: Asian" CDS 106..10377 /note="structural and nonstructural proteins" /codon_start=1 /product="polyprotein" /protein_id="AMK79469.1" /db_xref="GI:998961614" /translation="MKNPKKKSGGFRIVNMLKRGVARVSPFGGLKRLPAGLLLGHGPI RMVLAILAFLRFTAIKPSLGLINRWGSVGKKDAMEIIKKFKKDLAAMLRIINARKEKK RRGADTSVGIVGLLLTTAMAAEVTRRGSAYYMYLDRNDAGEAISFPTTLGMNKCYIQI MDLGHMCDATMSYECPMLDEGVEPDDVDCWCNTTSTWVVYGTCHHKKGEARRSRRAVT LPSHSTRKLQTRSQTWLESREYTKHLIRVENWIFRNPGFALAAAAIAWLLGSSTSQKV IYLVMILLIAPAYSIRCIGVSNRDFVEGMSGGTWVDVVLEHGGCVTAMAQDKPTVDIE LVTTTVSNMAEVRSYCYEASISDMASDSRCPTQGEAYLDKQSDTQYVCKRTLVDRGWG NGCGLFGKGSLVTCAKFACSKKMTGKSIQPENLEYRIMLSVHGSQHSGMLVNDTGHET DENRAKVEITPNSPRAEATLGGFGSLGLDCEPRTGLDFSDLYYLTMNNKHWLAHKEWF HDIPLPWHAGAATGTPHWNNKEALVEFKDAHAKRQTVVVLGSQEGAVHTALAGALEAE MDGAKGRLSSGHLKCRLKMDKLRLKGVSYSLCTAAFTFTKIPAETVDGTVTVEGQYGG TDGPCKVPAQMAVDMQTLTPVGRLITANPVITESTENSKMMLELDPPFGDSYIVIGVG EKKITHHWHRSGSTIGKAFEATVRGAKRMAVLGDTAWDFGSVGGALNSLGKGIHQIIG AAFKSLFGGMSWFSQILIGTLLMWLGLNTKNGSISLMCLALGGVLIFLSTAVSGGVGC SVDFSKKETRCGTGVFVYNDVEAWRDRYKYHPDSPRRLAAAVKQAWEDGICGISSVSR MENIMWRSVEGELNAILEENGVQLTVVVGSVKNPMWRGPQRLPVPVNELPHGWKAWGK SYFVRAAKTNNSFVVDGDTLKECPLKHRAWNSFLVEDHGFGVFHTSVWLKVREDYWLE CDPAVIGTAVKGKEAVHSDLGYWIESEKNDTWWLKRAHLIEMKTCEWPKSHTLWTDGI EESDLIIPKSLAGPLSHHNAREGYRTQMKGPWHSEELEIRFEECPGTKVHVEETCGTR GPSLRSTTASGRVIEEWCSRECTMPPLSFQAKDGCWYGMEIRPRKEPESNLVRSMVTA GSTDHMDHFSLGVLVILLMVQEGLKKRMTTKIIISTSMAVLVAMILGGFSMSDLAKLA ILMGATFAEMNTGGDVAHLALIAAFKVRPALLVSFIFRANWTPRESMLLALASCLLQT AISALEGDLMVLINGFALAWLAIRAMVVPRTDNITLAILAALTPLARGTLLVAWRAGL ATCGGFMLLSLKGKGSVKKNLPFVMALGLTAVRLVDPINVVGLLLLTRSGKRSWPPSE VLTAVGLICALAGGFAKADIEMAGPMAAVGLLIVSYVVSGKSVDMYIERAGDITWEKD AEVTGNSPRLDVALDESGDFSLVEDDGPPMREIILKVVLMTICGMNPIAIPFAAGAWY VYVKTGKRSGALWDVPAPKEVKKGETTDGVYRVMTRRLLGSTQVGVGVMQEGVFHTMW HVTKGSALRSGEGRLDPYWGDVKQDLVSYCGPWKLDAAWDGHSEVQLLAVPPGERARN IQTLPGIFKTKDGDIGAVALDYPAGTSGSPILDKCGRVIGLYGNGVVIKNGSYVSAIT QGRREEETPVECFEPSMLKKKQLTVLDLHPGAGKTRRVLPEIVREAIKTRLRTVILAP TRVVAAEMEEALRGLPVRYMTTAVNVTHSGTEIVDLMCHATFTSRLLQPIRVPNYNLY IMDEAHFTDPSSIAARGYISTRVEMGEAAAIFMTATPPGTRDAFPDSNSPIMDTEVEV PERAWSSGFDWVTEYSGKTVWFVPRVRNGNEIAACLTKAGKRVIQLSRKTFETEFQKT KHQEWDFVVTTDISEMGANFKADRVIDSRRCLKPVILGGERVILAGPMPVTHASAAQR RGRIGRNPNKPGDEYLYGGGCAETDEDHAHWLEARMLLDNIYLQDGLIASLYRPEADK VAAIEGEFKLRTEQRKTFVELMKRGDLPVWLAYQVASAGITYTDRRWCFDGTTNNTIM EDSVPAEVWTRHGEKRVLKPRWMDARVCSDHAALKSFKEFAAGKRGAAFGVMEALGTL PGHMTERFQEAIDNLAVLMRAETGSRPYKAAAAQLPETLETIMLLGLLGTVSLGIFFV LMRNKGIGKMGFGMVTLGASAWLMWLSEIEPARIACVLIVVFLLLVVLIPEPEKQRSP QDNQMAIIIMVAVGLLGLITANELGWLERTKSDLSHLMGRREEGATMGFSMDIDLRPA SAWAIYPALTSFITPAVQHAVTTSYNNYSLMAMATQAGVLFGMGKGMPFYAWDFGVPL LMIGCYSQLTPLTLIVAIILLVAHYMYLIPGLQAAAARAAQKRTAAGIMKNPVVEGIV VTDIDTMTIDPQVEKKMGQVLLMAVAVSSAILSRTAWGWGEAGALITAATSTLWEGSP NKYWNSSTATSLCNIFRGSYLAGASLIYTVTRNAGLVKRRGGGTGETLGEKWKARLNQ MSALEFYSYKKSGITEVCREEARRALKDGVATGGHAVSRGSAKLRWLVERGYLQPYGK VIDLGCGRGGWSYYAATIRKVQEVKGYTKGGPGHEEPVLVQSYGWNIVRLKSGVDVFH MAAEPCDTLLCDIGESSSSPEVEEARTLRVLSMVGDWLEKRPGAFCIKVLCPYTSTMM ETLERLQRRYGGGLVRVPLSRNSTHEMYWVSGAKSNTIKSVSTTSQLLLGRMDGPRRP VKYEEDVNLGSGTRAVVSCAEAPNMKIIGNRIERIRAEKAETWFFDENHPYRTWAYHG SYDAATQGSASSLINGVVRLLSKPWDVVTGVTGIAMTDTTPYGQQRVFKEKVDTRVPD PQEGTRQVMSMVSSWLWKELGKHKRPRVCTKEEFINKVRSNAALGAIFEEEKEWKTAV EAVNDPRFWALVDKEREHHLRGECQSCVYITMGKREKKQGEFGKAKGSRAIWYMWLGA RFLEFEALGFLNEDHWMGRENSGGGVEGLGLQRLGYVLEEMSRIPGGRMYADDTAGWD TRISRFDLENEALITNQMEKGHRALALAIIKYTYQNKVVKVLRPAEKGKTVMDIISRQ DQRGSGQVVTYALNTFTNLVVQLIRNMEAEEVLEMQDLWLLRRSEKVTNWLQSNGWDR LKRMAVSGDDCVVKPIDDRFAHALRFLNDMGKVRKDTQEWKPSTGWDNWEEVPFCSHH FNKLHLKDGRSIVVPCRHQDELIGRARVSPGAGWSIRETACLAKSYAQMWQLLYFHRR DLRLMANAICSSVPVDWVPTGRTTWSIHGKGEWMTTEDMLVAWNRVWIEENDHMEDKT PVTKWTDIPYLGKREDLWCGSLIGHRPRTTWAENIKNTVNMVRRIIGDEEKYMDYLST QVRYLGEEGSTPGVL" mat_peptide 106..480 /product="capsid protein" mat_peptide 481..750 /product="propeptide" mat_peptide 751..975 /product="membrane protein" mat_peptide 976..2490 /product="envelope protein" mat_peptide 2491..3576 /product="NS1" mat_peptide 3577..4230 /product="NS2A" mat_peptide 4231..4662 /product="NS2B" mat_peptide 4663..6471 /product="NS3" mat_peptide 6472..6912 /product="NS4A" mat_peptide 6913..8418 /product="NS4B" mat_peptide 8419..10374 /product="NS5" ORIGIN 1 gttgttactg ttgctgactc agactgcgac agttcgagtt tgaagcgaaa gctagcaaca 61 gtatcaacag gttttatttg gatttggaaa cgagagtttc tggtcatgaa aaacccaaaa 121 aagaaatccg gaggattccg gattgtcaat atgctaaaac gcggagtagc ccgtgtgagc 181 ccctttgggg gcttgaagag gctgccagcc ggacttctgc tgggtcatgg gcccatcagg 241 atggtcttgg caattctagc ctttttgaga ttcacggcaa tcaagccatc actgggtctc 301 atcaatagat ggggttcagt ggggaaaaaa gatgctatgg aaataataaa gaagttcaag 361 aaagatctgg ctgccatgct gagaataatc aatgctagga aggagaagaa gagacgaggc 421 gcagatacta gtgtcggaat tgttggcctc ctgctgacca cagctatggc agcggaggtc 481 actagacgtg ggagtgcata ctatatgtac ttggacagaa acgatgctgg ggaggccata 541 tcttttccaa ccacattggg gatgaataag tgttatatac agatcatgga tcttggacac 601 atgtgtgatg ccaccatgag ctatgaatgc cctatgctgg atgagggggt ggaaccagat 661 gacgtcgatt gttggtgcaa cacgacgtca acttgggttg tgtacggaac ctgccatcac 721 aaaaaaggtg aagcacggag atctagaaga gctgtgacgc tcccttccca ttccactagg 781 aagctgcaaa cgcggtcgca aacctggttg gaatcaagag aatacacaaa gcacttgatt 841 agagtcgaaa attggatatt caggaaccct ggcttcgcgt tagcagcagc tgccatcgct 901 tggcttttgg gaagctcaac gagccaaaaa gtcatatact tggtcatgat actgctgatt 961 gccccggcat acagcatcag gtgcatagga gtcagcaata gggactttgt ggaaggtatg 1021 tcaggtggga cttgggttga tgttgtcttg gaacatggag gttgtgtcac cgcaatggca 1081 caggacaaac cgactgtcga catagagctg gttacaacaa cagtcagcaa catggcggag 1141 gtaagatcct actgctatga ggcatcaata tcagacatgg cttcggacag ccgctgccca 1201 acacaaggtg aagcctacct tgacaagcaa tcagacactc aatatgtttg caaaagaacg 1261 ttagtggaca gaggctgggg aaatggatgt ggactttttg gcaaagggag tctggtgaca 1321 tgcgctaagt ttgcatgctc caagaaaatg accgggaaga gcatccagcc agagaatctg 1381 gagtaccgga taatgctgtc agttcatggc tcccagcaca gtgggatgct cgttaatgac 1441 acaggacatg aaactgatga gaatagagcg aaggttgaga taacgcccaa ttcaccaaga 1501 gccgaagcca ccctgggggg ttttggaagc ctaggacttg attgtgaacc gaggacaggc 1561 cttgactttt cagatttgta ttacttgact atgaataaca agcactggtt ggctcacaag 1621 gagtggttcc acgacattcc attaccttgg cacgctgggg cagccaccgg aactccacac 1681 tggaacaaca aagaagcact ggtagagttc aaggacgcac atgccaaaag gcaaactgtc 1741 gtggttctag ggagtcaaga aggagcagtt cacacggccc ttgctggagc tctggaggct 1801 gagatggatg gtgcaaaggg aaggctgtcc tctggccact tgaaatgtcg cctgaaaatg 1861 gataaactta gattgaaggg cgtgtcatac tccttgtgta ccgcagcgtt cacattcacc 1921 aagatcccgg ctgaaacagt ggacgggaca gtcacagtgg agggacagta cggagggaca 1981 gatggacctt gcaaggttcc agctcagatg gcggtggaca tgcagactct gaccccagtt 2041 gggaggttga taaccgctaa ccccgtaatc actgaaagca ctgagaactc taagatgatg 2101 ctggaacttg atccaccatt tggggactct tacattgtca taggagtcgg ggagaagaag 2161 atcacccacc actggcacag gagtggcagc accattggaa aagcatttga agccactgtg 2221 agaggtgcca agagaatggc agtcttggga gacacagcct gggactttgg atcagttgga 2281 ggcgctctca actcattggg caagggcatc catcaaatta ttggagcagc tttcaaatca 2341 ttgtttggag gaatgtcctg gttctcacaa attctcattg ggacgttgct gatgtggttg 2401 ggtctgaaca caaagaatgg atctatttcc cttatgtgct tggccttagg gggagtgttg 2461 atcttcttat ccacagccgt ctcaggtggt gtggggtgct cggtggactt ctcaaagaag 2521 gagacgagat gcggtacagg ggtgttcgtc tataacgatg ttgaagcctg gagggacagg 2581 tacaagtacc atcctgactc cccccgtaga ttggcagcag cagtcaagca agcctgggaa 2641 gatggtatct gcgggatctc ctctgtttca agaatggaaa acatcatgtg gagatcagta 2701 gaaggggagc tcaacgcaat cctggaagag aatggagttc aactgacggt cgttgtggga 2761 tctgtaaaaa accccatgtg gagaggtcca cagagattgc ccgtgcctgt gaacgagctg 2821 ccccacggct ggaaggcttg ggggaaatcg tacttcgtca gagcagcaaa gacaaataac 2881 agctttgtcg tggatggtga cacactgaag gaatgcccac tcaaacatag agcatggaac 2941 agctttcttg tggaggatca tgggttcggg gtatttcaca ctagtgtctg gctcaaggtt 3001 agagaagact attggttaga gtgtgatcca gccgttattg gaacagctgt taagggaaag 3061 gaggctgtac acagtgatct aggctactgg attgagagtg agaagaatga cacatggtgg 3121 ctgaagaggg cccatctgat cgagatgaaa acatgtgaat ggccaaagtc ccacacattg 3181 tggacagatg gaatagaaga gagtgatctg atcataccca agtctttagc tgggccactc 3241 agccatcaca atgccagaga gggctacagg acccaaatga aagggccatg gcacagtgaa 3301 gagcttgaaa ttcggtttga ggaatgccca ggcactaagg tccacgtgga ggaaacatgt 3361 ggaacaagag gaccatctct gagatcaacc actgcaagcg gaagggtgat cgaggaatgg 3421 tgctccaggg agtgcacaat gcccccactg tccttccagg ctaaagatgg ctgttggtat 3481 ggaatggaga taaggcccag gaaagaacca gaaagcaact tagtaaggtc aatggtgact 3541 gcaggatcaa ctgatcacat ggatcacttc tcccttggag tgcttgtgat tctgctcatg 3601 gtgcaggaag ggctgaagaa gagaatgacc acaaagatca tcataagcac atcaatggca 3661 gtgctggtag ctatgatcct gggaggattt tcaatgagtg acctggctaa gcttgcaatt 3721 ttgatgggtg ccaccttcgc ggaaatgaac actggaggag atgtagctca tctggcgctg 3781 atagcggcat tcaaagtcag accagcgttg ctggtatctt tcatcttcag agctaattgg 3841 acaccccgtg aaagcatgct gctggccttg gcctcgtgtc ttttgcaaac tgcgatctcc 3901 gccttggaag gcgacctgat ggttctcatc aatggttttg ctttggcctg gttggcaata 3961 cgagcgatgg ttgttccacg cactgataac atcaccttag caatcctggc tgctctgaca 4021 ccactggccc ggggcacact gcttgtggcg tggagagcag gccttgctac ttgcgggggg 4081 tttatgctcc tctctctgaa gggaaaaggc agtgtgaaga agaacttacc atttgtcatg 4141 gccctgggac taaccgctgt gaggctggtc gaccccatca acgtggtggg actgctgttg 4201 ctcacaagga gtgggaagcg gagctggccc cctagcgaag tactcacagc tgttggcctg 4261 atatgcgcat tggctggagg gttcgccaag gcagatatag agatggctgg gcccatggcc 4321 gcggtcggtc tgctaattgt cagttacgtg gtctcaggaa agagtgtgga catgtacatt 4381 gaaagagcag gtgacatcac atgggaaaaa gatgcggaag tcactggaaa cagtccccgg 4441 ctcgatgtgg cgctagatga gagtggtgat ttctccctgg tggaggatga cggtcccccc 4501 atgagagaga tcatactcaa ggtggtcctg atgaccatct gtggcatgaa cccaatagcc 4561 ataccctttg cagctggagc gtggtacgta tacgtgaaga ctggaaaaag gagtggtgct 4621 ctatgggatg tgcctgctcc caaggaagta aaaaaggggg agaccacaga tggagtgtac 4681 agagtaatga ctcgcagact gctaggttca acacaagttg gagtgggagt tatgcaagag 4741 ggggtctttc acactatgtg gcacgtcaca aaaggatccg cgctgagaag cggtgaaggg 4801 agacttgatc catactgggg agatgtcaag caggatctgg tgtcatactg tggtccatgg 4861 aagctagatg ccgcctggga cgggcacagc gaggtgcagc tcttggccgt gccccccgga 4921 gagagagcga ggaacatcca gactctgccc ggaatattta agacaaagga tggggacatt 4981 ggagcggttg cactggatta cccagcagga acttcaggat ctccaatcct agacaagtgt 5041 gggagagtga taggacttta tggcaatggg gtcgtgatca aaaatgggag ttatgttagt 5101 gccatcaccc aagggaggag ggaggaagag actcctgttg agtgcttcga gccttcgatg 5161 ctgaagaaga agcagctaac tgtcttagac ttgcatcctg gagctgggaa aaccaggaga 5221 gttcttcctg aaatagtccg tgaagccata aaaacaagac tccgtactgt gatcttggct 5281 ccaaccaggg ttgtcgctgc tgaaatggag gaggccctta gagggcttcc agtgcgttat 5341 atgacaacag cagtcaatgt cacccactct ggaacagaaa tcgtcgactt aatgtgccat 5401 gccaccttca cttcacgtct actacagcca attagagtcc ccaactataa tctgtatatt 5461 atggatgagg cccacttcac agatccctca agtatagcag caagaggata catttcaaca 5521 agggttgaga tgggcgaggc ggctgccatc ttcatgaccg ccacgccacc aggaacccgt 5581 gacgcatttc cggactccaa ctcaccaatt atggacaccg aagtggaagt cccagagaga 5641 gcctggagct caggctttga ttgggtgacg gagtattctg gaaaaacagt ttggtttgtt 5701 ccacgcgtga ggaacggcaa tgagatcgca gcttgtctga caaaggctgg aaaacgggtc 5761 atacagctca gcagaaagac ttttgagaca gagttccaga aaacaaaaca tcaagagtgg 5821 gactttgtcg tgacaactga catttcagag atgggcgcca actttaaagc tgaccgtgtc 5881 atagattcca ggagatgcct aaagccggtc atacttggtg gcgagagagt cattctggct 5941 ggacccatgc ctgtcacaca tgccagcgct gcccagagga gggggcgcat aggcaggaat 6001 cccaacaaac ctggagatga gtatctgtat ggaggtgggt gcgcagagac tgacgaagac 6061 catgcacact ggcttgaagc aagaatgctc cttgacaata tttacctcca agatggcctc 6121 atagcctcgc tctatcgacc tgaggccgac aaagtagcag ccattgaggg agagttcaag 6181 cttaggacgg agcaaaggaa gacctttgtg gaactcatga aaagaggaga tcttcctgtt 6241 tggctggcct atcaggttgc atctgccgga ataacctaca cagatagaag atggtgcttt 6301 gatggcacga ccaacaacac cataatggaa gacagtgtgc cggcagaggt gtggaccaga 6361 cacggagaga aaagagtgct caaaccgagg tggatggacg ccagagtttg ttcagatcat 6421 gcggccctga agtcattcaa ggagtttgcc gctgggaaaa gaggagcggc ttttggagtg 6481 atggaagccc tgggaacact gccaggacac atgacagaga gattccagga agccattgac 6541 aacctcgctg tgctcatgcg ggcagagact ggaagcaggc cttacaaagc cgcggcggcc 6601 caattgccgg agaccctaga gaccattatg cttttggggt tgctgggaac agtctcgctg 6661 ggaatctttt tcgtcttgat gaggaacaag ggcataggga agatgggctt tggaatggtg 6721 actcttgggg ccagcgcatg gctcatgtgg ctctcggaaa ttgagccagc cagaattgca 6781 tgtgtcctca ttgttgtgtt cctattgctg gtggtgctca tacctgagcc agaaaagcaa 6841 agatctcccc aggacaacca aatggccatc atcatcatgg tagcagtagg tcttctgggc 6901 ttgattaccg ccaatgaact cggatggttg gagagaacaa agagtgacct aagccatcta 6961 atgggaagga gagaggaggg ggcaaccatg ggattctcaa tggacattga cctgcggcca 7021 gcctcagctt gggccatcta tcctgccttg acatctttca ttaccccagc cgtccaacat 7081 gcagtgacca cttcatacaa caactactcc ttaatggcga tggccacgca agctggagtg 7141 ttgtttggta tgggcaaagg gatgccattc tacgcatggg actttggagt cccgctgcta 7201 atgataggtt gctactcaca attaacgccc ctgaccctaa tagtggccat cattttgctc 7261 gtggcgcact acatgtactt gatcccaggg ctgcaggcag cagctgcgcg tgctgcccag 7321 aagagaacgg cagctggcat catgaagaac cctgttgtgg agggaatagt ggtgactgac 7381 attgacacaa tgacaattga cccccaagtg gagaaaaaga tgggacaggt gctactcatg 7441 gcagtagccg tctccagcgc catactgtcg aggaccgcct gggggtgggg ggaggctggg 7501 gccctgatca cagccgcaac ttccactttg tgggaaggct ctccgaacaa gtactggaac 7561 tcctctacag ccacctcact gtgtaacatt tttaggggaa gttacttggc tggagcttct 7621 ctaatctaca cagtaacaag aaacgctggc ttggtcaaga gacgtggggg tggaacagga 7681 gagaccctgg gagagaaatg gaaggcccgc ttgaaccaga tgtcggccct ggagttctac 7741 tcctacaaaa agtcaggcat caccgaggtg tgcagagaag aggcccgccg cgccctcaag 7801 gacggtgtgg caacgggagg ccatgctgtg tcccgaggaa gtgcaaagct gagatggttg 7861 gtggagcggg gatacctgca gccctatgga aaggtcattg atcttggatg tggcagaggg 7921 ggctggagtt actacgccgc caccatccgc aaagttcaag aagtgaaagg atacacaaaa 7981 ggaggccctg gtcatgaaga acccgtgttg gtgcaaagct atgggtggaa catagtccgt 8041 cttaagagtg gggtggacgt ctttcatatg gcggctgagc cgtgtgacac gttgctgtgt 8101 gacataggtg agtcatcatc tagtcctgaa gtggaagaag cacggacgct cagagtcctc 8161 tccatggtgg gggattggct tgaaaaaaga ccaggagcct tttgtataaa agtgttgtgc 8221 ccatacacca gcactatgat ggaaaccctg gagcgactgc agcgtaggta tgggggagga 8281 ctggtcagag tgccactctc ccgcaactct acacatgaga tgtactgggt ctctggagcg 8341 aaaagcaaca ccataaaaag tgtgtccacc acgagccagc tcctcttggg gcgcatggac 8401 gggcctagga ggccagtgaa atatgaggag gatgtgaatc tcggctctgg cacgcgggct 8461 gtggtaagct gcgctgaagc tcccaacatg aagatcattg gtaaccgcat tgaaaggatc 8521 cgcgctgaga aagcggaaac gtggttcttt gacgagaacc acccatatag gacatgggct 8581 taccatggaa gctatgatgc cgccacacaa gggtcagcgt cctctctaat aaacggggtt 8641 gtcaggctcc tgtcaaaacc ctgggatgtg gtgactggag tcacaggaat agccatgacc 8701 gacaccacac cgtatggtca gcaaagagtt ttcaaggaaa aagtggacac tagggtgcca 8761 gacccccaag aaggcactcg tcaggttatg agcatggtct cttcctggtt gtggaaagag 8821 ctaggcaaac acaaacggcc acgagtctgt accaaagaag agttcatcaa caaggttcgt 8881 agcaatgcag cattaggggc aatatttgaa gaggaaaaag agtggaagac tgcagtggaa 8941 gctgtgaacg atccaaggtt ctgggctcta gtggacaagg aaagagagca ccacctgaga 9001 ggagagtgcc agagttgtgt gtacatcaca atgggaaaaa gagaaaagaa acaaggggaa 9061 tttggaaagg ccaagggcag ccgcgccatc tggtatatgt ggctaggggc tagatttcta 9121 gagttcgaag cccttggatt cttgaacgag gatcactgga tggggagaga gaactcagga 9181 ggtggtgttg aagggctggg attacaaaga ctcggatatg tcctagaaga gatgagtcgc 9241 ataccaggag gaaggatgta tgcagatgac actgctggct gggacacccg catcagcagg 9301 tttgatctgg agaatgaagc tctaatcacc aaccaaatgg agaaagggca cagggccttg 9361 gcattggcca taatcaagta cacataccaa aacaaagtgg taaaggtcct tagaccagct 9421 gaaaaaggga agacagttat ggacattatt tcgagacaag accaaagggg gagcggacaa 9481 gttgtcactt acgctctcaa cacatttacc aacctagtgg tgcaactcat tcggaatatg 9541 gaggctgagg aagttctaga gatgcaagac ttgtggctgc tgcggaggtc agagaaagtg 9601 accaactggt tgcagagcaa cggatgggat aggctcaaac gaatggcggt cagtggagat 9661 gattgcgttg tgaaaccaat tgatgatagg tttgcacatg ccctcaggtt cttgaatgat 9721 atgggaaaag ttaggaagga cacacaagag tggaaaccct caactggatg ggacaactgg 9781 gaagaagttc ccttctgctc ccaccacttc aacaagctcc atctcaagga cgggaggtcc 9841 attgtggttc cctgccgcca ccaagatgaa ctgattggcc gggcccgcgt ctctccaggg 9901 gcgggatgga gcatccggga gactgcttgc ctagcaaaat catatgcgca aatgtggcag 9961 ctcctttatt tccacagaag ggacctccga ctgatggcca atgccatttg ttcatctgtg 10021 ccagttgact gggttccaac tgggagaact acctggtcaa tccatggaaa gggagaatgg 10081 atgaccactg aagacatgct tgtggcgtgg aacagagtgt ggattgagga gaacgaccac 10141 atggaagaca agaccccagt cacgaaatgg acagacattc cctatttggg aaaaagggaa 10201 gacttgtggt gtggatctct catagggcac agaccgcgca ccacctgggc tgagaacatt 10261 aaaaacacag tcaacatggt gcgcaggatc ataggtgatg aagaaaagta catggactac 10321 ctatccaccc aagttcgcta cttgggtgaa gaagggtcta cacctggagt gctgtaagca 10381 ccaatcttaa tgttgtcagg cctgctagtc agccacagct tggggaaagc tgtgcagcct 10441 gtgacccccc caggagaagc tgggaaacca agcctatagt caggccgaga acgccatggc 10501 acggaagaag ccatgctgcc tgtgagcccc tcagaggaca ctgagtcaaa aaaccccacg 10561 cgcttggagg cgcaggatgg gaaaagaagg tggcgacctt ccccaccctt caatctgggg 10621 cctgaactgg agatcagctg tggatctcca gaagagggac tagtggttag aggaga

In addition to the partial Zika sequence from the urine of the first Zika import in China, National Institute for Viral Diseases Control and Prevention in Beijing has now released a full sequence from serum. http://www.ncbi.nlm.nih.gov/nuccore/KU744693

Sequences producing significant alignments:Select:AllNone Selected:0 AlignmentsDownloadGenBankGraphicsDistance tree of resultsShow/hide columns of the table presenting sequences producing significant alignmentsSequences producing significant alignments:Select for downloading or viewing reportsDescriptionMax scoreTotal scoreQuery coverE valueIdentAccessionSelect seq gb|KU497555.1|Zika virus isolate Brazil-ZKV2015, complete genome1852518525100%0.0100%KU497555.1Select seq gb|KU509998.1|Zika virus strain Haiti/1225/2014, complete genome183951839599%0.099%KU509998.1Select seq gb|KJ776791.1|Zika virus strain H/PF/2013 polyprotein gene, complete cds183901839099%0.099%KJ776791.1Select seq gb|KU321639.1|Zika virus strain ZikaSPH2015, complete genome183811838199%0.099%KU321639.1Select seq gb|KU707826.1|Zika virus isolate SSABR1, complete genome183721837299%0.099%KU707826.1Select seq gb|KU647676.1|Zika virus strain MRS_OPY_Martinique_PaRi_2015 polyprotein gene, complete cds183721837299%0.099%KU647676.1Select seq gb|KU365779.1|Zika virus strain BeH819966 polyprotein gene, complete cds183721837299%0.099%KU365779.1Select seq gb|KU365780.1|Zika virus strain BeH815744 polyprotein gene, complete cds183591835999%0.099%KU365780.1Select seq gb|KU365777.1|Zika virus strain BeH818995 polyprotein gene, complete cds183541835499%0.099%KU365777.1Select seq gb|KU501217.1|Zika virus strain 8375 polyprotein gene, complete cds183501835099%0.099%KU501217.1Select seq gb|KU527068.1|Zika virus strain Natal RGN, complete genome183451834599%0.099%KU527068.1Select seq gb|KU501216.1|Zika virus strain 103344 polyprotein gene, complete cds183451834599%0.099%KU501216.1Select seq gb|KU365778.1|Zika virus strain BeH819015 polyprotein gene, complete cds183411834199%0.099%KU365778.1Select seq gb|KU312312.1|Zika virus isolate Z1106033 polyprotein gene, complete cds183411834199%0.099%KU312312.1Select seq gb|KU501215.1|Zika virus strain PRVABC59, complete genome183321833299%0.099%KU501215.1Select seq gb|KU740184.1|Zika virus isolate GD01 polyprotein gene, complete cds183051830599%0.099%KU740184.1Select seq gb|KU744693.1|Zika virus isolate VE_Ganxian, complete genome181461814699%0.099%KU744693.1Select seq gb|KU681081.3|Zika virus isolate Zika virus/H.sapiens-tc/THA/2014/SV0127- 14, complete genome180581805899%0.099%KU681081.3Select seq gb|JN860885.1|Zika virus isolate FSS13025 polyprotein gene, partial cds177531775399%0.098%JN860885.1Select seq gb|KF993678.1|Zika virus strain PLCal_ZV from Canada polyprotein gene, partial cds177151771598%0.099%KF993678.1Select seq gb|EU545988.1|Zika virus polyprotein gene, complete cds176031760399%0.098%EU545988.1Select seq gb|KU681082.3|Zika virus isolate Zika virus/H.sapiens-tc/PHL/2012/CPC-0740, complete genome174571745799%0.098%KU681082.3Select seq gb|HQ234499.1|Zika virus isolate P6-740 polyprotein gene, partial cds164111641199%0.095%HQ234499.

Sequences producing significant alignments:Select:AllNone Selected:0 AlignmentsDownloadGenBankGraphicsDistance tree of resultsShow/hide columns of the table presenting sequences producing significant alignmentsSequences producing significant alignments:Select for downloading or viewing reportsDescriptionMax scoreTotal scoreQuery coverE valueIdentAccessionSelect seq gb|KU497555.1|Zika virus isolate Brazil-ZKV2015, complete genome11931193100%0.0100%KU497555.1Select seq gb|KU232299.1|Zika virus isolate 015ZV_PEBR15 NS5 protein gene, partial cds11931193100%0.0100%KU232299.1Select seq gb|KU232298.1|Zika virus isolate 050ZV_PEBR15 NS5 protein gene, partial cds11931193100%0.0100%KU232298.1Select seq gb|KU232296.1|Zika virus isolate 045ZV_PEBR15 NS5 protein gene, partial cds11931193100%0.0100%KU232296.1Select seq gb|KU232295.1|Zika virus isolate 068ZV_PEBR15 NS5 protein gene, partial cds11931193100%0.0100%KU232295.1Select seq gb|KU232294.1|Zika virus isolate 061ZV_PEBR15 NS5 protein gene, partial cds11931193100%0.0100%KU232294.1Select seq gb|KU232290.1|Zika virus isolate 036ZV_PEBR15 NS5 protein gene, partial cds11931193100%0.0100%KU232290.1Select seq gb|KU232289.1|Zika virus isolate 020ZV_PEBR15 NS5 protein gene, partial cds11931193100%0.0100%KU232289.1Select seq gb|KU232288.1|Zika virus isolate 001ZV_PEBR15 NS5 protein gene, partial cds11931193100%0.0100%KU232288.1Select seq gb|KU556802.1|Zika virus isolate MEX/InDRE/14/2015 NS5 protein gene, partial cds11931193100%0.0100%KU556802.1Select seq gb|KU647676.1|Zika virus strain MRS_OPY_Martinique_PaRi_2015 polyprotein gene, complete cds11931193100%0.0100%KU647676.1Select seq gb|KU232300.1|Zika virus isolate 067ZV_PEBR15 NS5 protein gene, partial cds11891189100%0.099%KU232300.1Select seq gb|KU232293.1|Zika virus isolate 057ZV_PEBR15 NS5 protein gene, partial cds11871187100%0.099%KU232293.1Select seq gb|KU232292.1|Zika virus isolate 054ZV_PEBR15 NS5 protein gene, partial cds11871187100%0.099%KU232292.1Select seq gb|KU509998.1|Zika virus strain Haiti/1225/2014, complete genome11871187100%0.099%KU509998.1Select seq gb|KU321639.1|Zika virus strain ZikaSPH2015, complete genome11871187100%0.099%KU321639.1Select seq gb|KM078936.1|Zika virus strain CHI1410214 NS5 protein gene, partial cds11871187100%0.099%KM078936.1Select seq gb|KJ873160.1|Zika virus isolate NC14-03042014-3481 nonstructural protein 5 gene, partial cds11871187100%0.099%KJ873160.1Select seq gb|KJ776791.1|Zika virus strain H/PF/2013 polyprotein gene, complete cds11871187100%0.099%KJ776791.1Select seq gb|KM078961.1|Zika virus strain CHI2612114 NS5 protein gene, partial cds11861186100%0.099%KM078961.1Select seq gb|KU740184.1|Zika virus isolate GD01 polyprotein gene, complete cds11841184100%0.099%KU740184.1Select seq gb|KU707826.1|Zika virus isolate SSABR1, complete genome11841184100%0.099%KU707826.1Select seq gb|KU527068.1|Zika virus strain Natal RGN, complete genome11841184100%0.099%KU527068.1Select seq gb|KU232297.1|Zika virus isolate 049ZV_PEBR15 NS5 protein gene, partial cds11841184100%0.099%KU232297.1Select seq gb|KU501217.1|Zika virus strain 8375 polyprotein gene, complete cds11841184100%0.099%KU501217.1Select seq gb|KU501216.1|Zika virus strain 103344 polyprotein gene, complete cds11841184100%0.099%KU501216.1Select seq gb|KU501215.1|Zika virus strain PRVABC59, complete genome11841184100%0.099%KU501215.1Select seq gb|KU365780.1|Zika virus strain BeH815744 polyprotein gene, complete cds11841184100%0.099%KU365780.1Select seq gb|KU365779.1|Zika virus strain BeH819966 polyprotein gene, complete cds11841184100%0.099%KU365779.1Select seq gb|KU365777.1|Zika virus strain BeH818995 polyprotein gene, complete cds11841184100%0.099%KU365777.1Select seq gb|KM078930.1|Zika virus strain CHI2283714 NS5 protein gene, partial cds11841184100%0.099%KM078930.1Select seq gb|KM078971.1|Zika virus strain CHI2613014 NS5 protein gene, partial cds11801180100%0.099%KM078971.1Select seq gb|KM078970.1|Zika virus strain CHI2490414 NS5 protein gene, partial cds11801180100%0.099%KM078970.1Select seq gb|KM078933.1|Zika virus strain CHI1058514 NS5 protein gene, partial cds11801180100%0.099%KM078933.1Select seq gb|KU232291.1|Zika virus isolate 051ZV_PEBR15 NS5 protein gene, partial cds11781178100%0.099%KU232291.1Select seq gb|KU365778.1|Zika virus strain BeH819015 polyprotein gene, complete cds11781178100%0.099%KU365778.1Select seq gb|KU312312.1|Zika virus isolate Z1106033 polyprotein gene, complete cds11781178100%0.099%KU312312.1Select seq gb|KM078929.1|Zika virus strain CHI1805214 NS5 protein gene, partial cds11781178100%0.099%KM078929.1Select seq gb|KF993678.1|Zika virus strain PLCal_ZV from Canada polyprotein gene, partial cds11691169100%0.099%KF993678.1Select seq gb|KU744693.1|Zika virus isolate VE_Ganxian, complete genome11661166100%0.099%KU744693.1Select seq gb|KU681081.3|Zika virus isolate Zika virus/H.sapiens-tc/THA/2014/SV0127- 14, complete genome11601160100%0.099%KU681081.3Select seq gb|KU179098.1|Zika virus isolate JMB-185 nonstructural protein 5 gene, partial cds11601160100%0.099%KU179098.1Select seq gb|JN860885.1|Zika virus isolate FSS13025 polyprotein gene, partial cds11391139100%0.098%JN860885.1Select seq gb|EU545988.1|Zika virus polyprotein gene, complete cds11331133100%0.098%EU545988.1Select seq gb|KU681082.3|Zika virus isolate Zika virus/H.sapiens-tc/PHL/2012/CPC-0740, complete genome11241124100%0.098%KU681082.3Select seq gb|KJ873161.1|Zika virus isolate NC14-02042014-3220 nonstructural protein 5 gene, partial cds1108110893%0.099%KJ873161.1Select seq gb|HQ234499.1|Zika virus isolate P6-740 polyprotein gene, partial cds10251025100%0.094%HQ234499.1Select seq gb|KM851039.1|Zika virus strain SV0127/14 nonstructural protein 5 gene, partial cds90290277%0.099%KM851039.1Select seq gb|KM851038.1|Zika virus strain CPC-0740 nonstructural protein 5 gene, partial cds88188177%0.098%KM851038.1

Sequences producing significant alignments:Select:AllNone Selected:0 AlignmentsDownloadGenBankGraphicsDistance tree of resultsShow/hide columns of the table presenting sequences producing significant alignmentsSequences producing significant alignments:Select for downloading or viewing reportsDescriptionMax scoreTotal scoreQuery coverE valueIdentAccessionSelect seq gb|KU179098.1|Zika virus isolate JMB-185 nonstructural protein 5 gene, partial cds20712071100%0.0100%KU179098.1Select seq gb|KF993678.1|Zika virus strain PLCal_ZV from Canada polyprotein gene, partial cds20352035100%0.099%KF993678.1Select seq gb|KU509998.1|Zika virus strain Haiti/1225/2014, complete genome20302030100%0.099%KU509998.1Select seq gb|KJ776791.1|Zika virus strain H/PF/2013 polyprotein gene, complete cds20302030100%0.099%KJ776791.1Select seq gb|KU497555.1|Zika virus isolate Brazil-ZKV2015, complete genome20262026100%0.099%KU497555.1Select seq gb|KU647676.1|Zika virus strain MRS_OPY_Martinique_PaRi_2015 polyprotein gene, complete cds20262026100%0.099%KU647676.1Select seq gb|KU501217.1|Zika virus strain 8375 polyprotein gene, complete cds20262026100%0.099%KU501217.1Select seq gb|KU501216.1|Zika virus strain 103344 polyprotein gene, complete cds20262026100%0.099%KU501216.1Select seq gb|KU501215.1|Zika virus strain PRVABC59, complete genome20212021100%0.099%KU501215.1Select seq gb|KU321639.1|Zika virus strain ZikaSPH2015, complete genome20212021100%0.099%KU321639.1Select seq gb|KU527068.1|Zika virus strain Natal RGN, complete genome20172017100%0.099%KU527068.1Select seq gb|KU740184.1|Zika virus isolate GD01 polyprotein gene, complete cds20122012100%0.099%KU740184.1Select seq gb|KU707826.1|Zika virus isolate SSABR1, complete genome20122012100%0.099%KU707826.1Select seq gb|KU365780.1|Zika virus strain BeH815744 polyprotein gene, complete cds20122012100%0.099%KU365780.1Select seq gb|KU365779.1|Zika virus strain BeH819966 polyprotein gene, complete cds20122012100%0.099%KU365779.1Select seq gb|KU365777.1|Zika virus strain BeH818995 polyprotein gene, complete cds20122012100%0.099%KU365777.1Select seq gb|KU312312.1|Zika virus isolate Z1106033 polyprotein gene, complete cds20122012100%0.099%KU312312.1Select seq gb|KU365778.1|Zika virus strain BeH819015 polyprotein gene, complete cds20032003100%0.099%KU365778.1Select seq gb|KU681081.3|Zika virus isolate Zika virus/H.sapiens-tc/THA/2014/SV0127- 14, complete genome19991999100%0.099%KU681081.3Select seq gb|JN860885.1|Zika virus isolate FSS13025 polyprotein gene, partial cds19991999100%0.099%JN860885.1Select seq gb|KU744693.1|Zika virus isolate VE_Ganxian, complete genome19941994100%0.099%KU744693.1Select seq gb|EU545988.1|Zika virus polyprotein gene, complete cds19841984100%0.098%EU545988.1Select seq gb|KU681082.3|Zika virus isolate Zika virus/H.sapiens-tc/PHL/2012/CPC-0740, complete genome19631963100%0.098%KU681082.3Select seq gb|HQ234499.1|Zika virus isolate P6-740 polyprotein gene, partial cds18191819100%0.095%HQ234499.1Select seq gb|KM078936.1|Zika virus strain CHI1410214 NS5 protein gene, partial cds1710171084%0.099%KM078936.1Select seq gb|KM078961.1|Zika virus strain CHI2612114 NS5 protein gene, partial cds1709170984%0.099%KM078961.1Select seq gb|KM078930.1|Zika virus strain CHI2283714 NS5 protein gene, partial cds1707170784%0.099%KM078930.1Select seq gb|KM078971.1|Zika virus strain CHI2613014 NS5 protein gene, partial cds1703170384%0.099%KM078971.1Select seq gb|KM078970.1|Zika virus strain CHI2490414 NS5 protein gene, partial cds1703170384%0.099%KM078970.1Select seq gb|KM078933.1|Zika virus strain CHI1058514 NS5 protein gene, partial cds1703170384%0.099%KM078933.1Select seq gb|KM078929.1|Zika virus strain CHI1805214 NS5 protein gene, partial cds1701170184%0.099%KM078929.1Select seq gb|KJ873160.1|Zika virus isolate NC14-03042014-3481 nonstructural protein 5 gene, partial cds1579157977%0.099%KJ873160.1

Sequences producing significant alignments:Select:AllNone Selected:0 AlignmentsDownloadGenBankGraphicsDistance tree of resultsShow/hide columns of the table presenting sequences producing significant alignmentsSequences producing significant alignments:Select for downloading or viewing reportsDescriptionMax scoreTotal scoreQuery coverE valueIdentAccessionSelect seq gb|KU740184.1|Zika virus isolate GD01 polyprotein gene, complete cds508508100%3e-140100%KU740184.1Select seq gb|KU527068.1|Zika virus strain Natal RGN, complete genome508508100%3e-140100%KU527068.1Select seq gb|KU647676.1|Zika virus strain MRS_OPY_Martinique_PaRi_2015 polyprotein gene, complete cds508508100%3e-140100%KU647676.1Select seq gb|KU509998.1|Zika virus strain Haiti/1225/2014, complete genome508508100%3e-140100%KU509998.1Select seq gb|KU365778.1|Zika virus strain BeH819015 polyprotein gene, complete cds508508100%3e-140100%KU365778.1Select seq gb|KU312315.1|Zika virus isolate Z1106027 polyprotein gene, partial cds508508100%3e-140100%KU312315.1Select seq gb|KU312314.1|Zika virus isolate Z1106031 polyprotein gene, partial cds508508100%3e-140100%KU312314.1Select seq gb|KU312313.1|Zika virus isolate Z1106032 polyprotein gene, partial cds508508100%3e-140100%KU312313.1Select seq gb|KM212966.1|Zika virus isolate NC13(FP)-26112013-22072 glycoprotein gene, partial cds508508100%3e-140100%KM212966.1Select seq gb|KJ579441.1|Zika virus isolate PF13-CP221013c polyprotein gene, partial cds508508100%3e-140100%KJ579441.1Select seq dbj|AB908162.1|Zika virus gene for polyprotein, partial cds, strain: ZIKV Hu/Tahiti/01u/2014NIID508508100%3e-140100%AB908162.1Select seq gb|KU744693.1|Zika virus isolate VE_Ganxian, complete genome502502100%1e-13899%KU744693.1Select seq gb|KU497555.1|Zika virus isolate Brazil-ZKV2015, complete genome502502100%1e-13899%KU497555.1Select seq gb|KU707826.1|Zika virus isolate SSABR1, complete genome502502100%1e-13899%KU707826.1Select seq gb|KU501217.1|Zika virus strain 8375 polyprotein gene, complete cds502502100%1e-13899%KU501217.1Select seq gb|KU501216.1|Zika virus strain 103344 polyprotein gene, complete cds502502100%1e-13899%KU501216.1Select seq gb|KU501215.1|Zika virus strain PRVABC59, complete genome502502100%1e-13899%KU501215.1Select seq gb|KU365780.1|Zika virus strain BeH815744 polyprotein gene, complete cds502502100%1e-13899%KU365780.1Select seq gb|KU365779.1|Zika virus strain BeH819966 polyprotein gene, complete cds502502100%1e-13899%KU365779.1Select seq gb|KU365777.1|Zika virus strain BeH818995 polyprotein gene, complete cds502502100%1e-13899%KU365777.1Select seq gb|KU312312.1|Zika virus isolate Z1106033 polyprotein gene, complete cds502502100%1e-13899%KU312312.1Select seq gb|KU321639.1|Zika virus strain ZikaSPH2015, complete genome502502100%1e-13899%KU321639.1Select seq gb|KM212965.1|Zika virus isolate NC13(FP)-20112013-22015 glycoprotein gene, partial cds502502100%1e-13899%KM212965.1Select seq gb|KM212964.1|Zika virus isolate NC14-17042014-4554 glycoprotein gene, partial cds502502100%1e-13899%KM212964.1Select seq gb|KM212963.1|Zika virus isolate NC14-23012014-250 glycoprotein gene, partial cds502502100%1e-13899%KM212963.1Select seq gb|KJ776791.1|Zika virus strain H/PF/2013 polyprotein gene, complete cds502502100%1e-13899%KJ776791.1Select seq gb|KJ680134.1|Zika virus strain PF13-091213-121 polyprotein gene, partial cds502502100%1e-13899%KJ680134.1Select seq gb|KU681081.3|Zika virus isolate Zika virus/H.sapiens-tc/THA/2014/SV0127- 14, complete genome499499100%2e-13799%KU681081.3Select seq gb|JN860885.1|Zika virus isolate FSS13025 polyprotein gene, partial cds499499100%2e-13799%JN860885.1Select seq gb|KF993678.1|Zika virus strain PLCal_ZV from Canada polyprotein gene, partial cds49149199%2e-13599%KF993678.1Select seq gb|KU681082.3|Zika virus isolate Zika virus/H.sapiens-tc/PHL/2012/CPC-0740, complete genome484484100%4e-13398%KU681082.3Select seq gb|KU646828.1|Zika virus isolate Si322 polyprotein gene, partial cds48448495%4e-133100%KU646828.1Select seq gb|EU545988.1|Zika virus polyprotein gene, complete cds484484100%4e-13398%EU545988.1Select seq gb|KU686218.1|Zika virus isolate MEX/InDRE/14/2015 polyprotein gene, partial cds480480100%4e-13298%KU686218.1Select seq gb|KU646827.1|Zika virus isolate Si323 polyprotein gene, partial cds47947995%2e-13199%KU646827.1Select seq gb|KJ634273.1|Zika virus strain CK-ISL 2014 E protein (E) gene, partial cds47947995%2e-13199%KJ634273.1Select seq gb|HQ234499.1|Zika virus isolate P6-740 polyprotein gene, partial cds439439100%1e-11995%HQ234499.1Select seq gb|KF268949.1|Zika virus isolate ARB15076 polyprotein gene, complete cds417417100%4e-11393%KF268949.1Select seq gb|KT381874.1|Zika virus strain Zika1697_BR-RJ/2015 envelope protein gene, partial cds41641684%2e-11299%KT381874.1

28 February 2016CHP notified of two additional imported cases of Zika Virus Infection in Mainland The Centre for Health Protection (CHP) of the Department of Health (DH) received notification last night (February 27) of two additional imported cases of Zika Virus Infection in the Mainland from the National Health and Family Planning Commission and the Health and Family Planning Commission of Guangdong Province, and again urged the public, particularly pregnant women, those planning pregnancy and immunocompromised patients, to adopt strict anti-mosquito measures during travel. According to the health authorities in the Mainland, the two cases involved a girl aged eight and her brother aged six. The patients live in Venezuela. They departed Venezuela for Guangdong and the boy developed fever during the journey. Upon their arrival at Baiyun International Airport in Guangzhou on February 25, his condition was discovered by the local Entry-Exit Inspection and Quarantine Bureau and the sibling were then hospitalised for isolation and management. The girl was also found to have skin rash. The cases were laboratory confirmed by the Family Planning Commission of Guangdong Province on February 27. At present, they were in stable condition and still hospitalised for isolation and management. The patients did not pass through Hong Kong. "Routine health surveillance on the body temperature of inbound travellers at all boundary control points is ongoing. Suspected cases will be referred to healthcare facilities for follow-up. However, at present, around 70 to 80 per cent of infected people are asymptomatic and most can recover fully. Therefore, we again urge those arriving from Zika-affected areas to apply insect repellent for 14 days upon arrival to reduce the risk of transmission," the spokesman for the DH said. The DH has been closely working with the travel industry and stakeholders, especially agents operating tours in Zika-affected areas and personnel receiving travellers in those areas (particularly pregnant women), to regularly update them on the latest disease information and health advice. As long as there is international travel, there is always a risk of introduction of Zika virus to Hong Kong. As asymptomatic infection is very common and the potential vector, Aedes albopictus, is present locally, there is also risk of local spread in case Zika is introduced to Hong Kong. The public should pay special attention to the countries and areas with reported autochthonous Zika virus transmission or locally acquired infection and those with indication of viral circulation earlier announced by the World Health Organization (WHO). The DH has been maintaining close liaison with the WHO as well as overseas, neighbouring and Mainland health authorities to closely monitor the latest developments of Zika. Locally, no human Zika cases have been reported to the CHP to date. To prevent Zika Virus Infection, in addition to general anti-mosquito measures, the DH drew the public's attention to the special notes below: A. Travelling abroad * If going to areas with ongoing Zika transmission (affected areas), travellers, especially those with immune disorders or severe chronic illnesses, should arrange consultation with a doctor at least six weeks before the trip, and take extra preventive measures to avoid mosquito bites;* Those arriving from affected areas should apply insect repellent for 14 days upon arrival. If feeling unwell, e.g. having fever, they should seek medical advice as soon as possible, and provide travel details to a doctor; B. Pregnant women and those preparing for pregnancy * Pregnant women and those preparing for pregnancy should consider deferring their trip to affected areas. Those who must travel should seek medical advice from their doctor before the trip, adopt contraception if appropriate, strictly follow steps to avoid mosquito bites during the trip, and consult and reveal their travel history to their doctor if symptoms develop after the trip. Women preparing for pregnancy are advised to continue to adopt contraception for 28 days after returning from these areas; and C. Special notes for prevention of sexual transmission regarding potential adverse pregnancy outcomes * Pregnant women should not have sex with male partners who have travelled to areas with ongoing Zika virus transmission (affected areas), or else condoms should be used throughout the pregnancy;* Any male traveller returning from affected areas should:(i) abstain from sex with his pregnant partner, or else use condoms throughout the pregnancy; and(ii) use a condom for at least six months if his female partner may get pregnant. The public may visit the pages below for more disease information and health advice: * The CHP's Zika page (www.chp.gov.hk/en/view_content/43086.html);* The Zika page of the DH's Travel Health Service (www.travelhealth.gov.hk/english/popup/popup_zika.html);* The Outbound Travel Alert page of the Security Bureau (www.sb.gov.hk/eng/ota); and* Anti-mosquito precautions for women (www.fhs.gov.hk/english/health_info/woman/30014.html). Ends/Sunday, February 28, 2016 http://www.chp.gov.hk/en/content/116/43604.html

Match update Sequences producing significant alignments:Select:AllNone Selected:0 AlignmentsDownloadGenBankGraphicsDistance tree of resultsShow/hide columns of the table presenting sequences producing significant alignmentsSequences producing significant alignments:Select for downloading or viewing reportsDescriptionMax scoreTotal scoreQuery coverE valueIdentAccessionSelect seq gb|KU497555.1|Zika virus isolate Brazil-ZKV2015, complete genome12211221100%0.0100%KU497555.1Select seq gb|KU232299.1|Zika virus isolate 015ZV_PEBR15 NS5 protein gene, partial cds12211221100%0.0100%KU232299.1Select seq gb|KU232298.1|Zika virus isolate 050ZV_PEBR15 NS5 protein gene, partial cds12211221100%0.0100%KU232298.1Select seq gb|KU232296.1|Zika virus isolate 045ZV_PEBR15 NS5 protein gene, partial cds12211221100%0.0100%KU232296.1Select seq gb|KU232295.1|Zika virus isolate 068ZV_PEBR15 NS5 protein gene, partial cds12211221100%0.0100%KU232295.1Select seq gb|KU232294.1|Zika virus isolate 061ZV_PEBR15 NS5 protein gene, partial cds12211221100%0.0100%KU232294.1Select seq gb|KU232290.1|Zika virus isolate 036ZV_PEBR15 NS5 protein gene, partial cds12211221100%0.0100%KU232290.1Select seq gb|KU232289.1|Zika virus isolate 020ZV_PEBR15 NS5 protein gene, partial cds12211221100%0.0100%KU232289.1Select seq gb|KU232288.1|Zika virus isolate 001ZV_PEBR15 NS5 protein gene, partial cds12211221100%0.0100%KU232288.1Select seq gb|KU556802.1|Zika virus isolate MEX/InDRE/14/2015 NS5 protein gene, partial cds12211221100%0.0100%KU556802.1Select seq gb|KU647676.1|Zika virus strain MRS_OPY_Martinique_PaRi_2015 polyprotein gene, complete cds12211221100%0.0100%KU647676.1Select seq gb|KU232300.1|Zika virus isolate 067ZV_PEBR15 NS5 protein gene, partial cds12181218100%0.099%KU232300.1Select seq gb|KU232293.1|Zika virus isolate 057ZV_PEBR15 NS5 protein gene, partial cds12161216100%0.099%KU232293.1Select seq gb|KU232292.1|Zika virus isolate 054ZV_PEBR15 NS5 protein gene, partial cds12161216100%0.099%KU232292.1Select seq gb|KU509998.1|Zika virus strain Haiti/1225/2014, complete genome12161216100%0.099%KU509998.1Select seq gb|KU321639.1|Zika virus strain ZikaSPH2015, complete genome12161216100%0.099%KU321639.1Select seq gb|KM078936.1|Zika virus strain CHI1410214 NS5 protein gene, partial cds12161216100%0.099%KM078936.1Select seq gb|KJ873160.1|Zika virus isolate NC14-03042014-3481 nonstructural protein 5 gene, partial cds12161216100%0.099%KJ873160.1Select seq gb|KJ776791.1|Zika virus strain H/PF/2013 polyprotein gene, complete cds12161216100%0.099%KJ776791.1Select seq gb|KM078961.1|Zika virus strain CHI2612114 NS5 protein gene, partial cds12121212100%0.099%KM078961.1Select seq gb|KU740184.1|Zika virus isolate GD01 polyprotein gene, complete cds12101210100%0.099%KU740184.1Select seq gb|KU707826.1|Zika virus isolate SSABR1, complete genome12101210100%0.099%KU707826.1Select seq gb|KU527068.1|Zika virus strain Natal RGN, complete genome12101210100%0.099%KU527068.1Select seq gb|KU232297.1|Zika virus isolate 049ZV_PEBR15 NS5 protein gene, partial cds12101210100%0.099%KU232297.1Select seq gb|KU501217.1|Zika virus strain 8375 polyprotein gene, complete cds12101210100%0.099%KU501217.1Select seq gb|KU501216.1|Zika virus strain 103344 polyprotein gene, complete cds12101210100%0.099%KU501216.1Select seq gb|KU501215.1|Zika virus strain PRVABC59, complete genome12101210100%0.099%KU501215.1Select seq gb|KU365780.1|Zika virus strain BeH815744 polyprotein gene, complete cds12101210100%0.099%KU365780.1Select seq gb|KU365779.1|Zika virus strain BeH819966 polyprotein gene, complete cds12101210100%0.099%KU365779.1Select seq gb|KU365777.1|Zika virus strain BeH818995 polyprotein gene, complete cds12101210100%0.099%KU365777.1Select seq gb|KM078930.1|Zika virus strain CHI2283714 NS5 protein gene, partial cds12101210100%0.099%KM078930.1Select seq gb|KM078971.1|Zika virus strain CHI2613014 NS5 protein gene, partial cds12061206100%0.099%KM078971.1Select seq gb|KM078970.1|Zika virus strain CHI2490414 NS5 protein gene, partial cds12061206100%0.099%KM078970.1Select seq gb|KM078933.1|Zika virus strain CHI1058514 NS5 protein gene, partial cds12061206100%0.099%KM078933.1Select seq gb|KU232291.1|Zika virus isolate 051ZV_PEBR15 NS5 protein gene, partial cds12051205100%0.099%KU232291.1Select seq gb|KU365778.1|Zika virus strain BeH819015 polyprotein gene, complete cds12051205100%0.099%KU365778.1Select seq gb|KU312312.1|Zika virus isolate Z1106033 polyprotein gene, complete cds12051205100%0.099%KU312312.1Select seq gb|KM078929.1|Zika virus strain CHI1805214 NS5 protein gene, partial cds12051205100%0.099%KM078929.1Select seq gb|KF993678.1|Zika virus strain PLCal_ZV from Canada polyprotein gene, partial cds11941194100%0.099%KF993678.1Select seq gb|KU744693.1|Zika virus isolate VE_Ganxian, complete genome11881188100%0.099%KU744693.1Select seq gb|KU681081.3|Zika virus isolate Zika virus/H.sapiens-tc/THA/2014/SV0127- 14, complete genome11821182100%0.099%KU681081.3Select seq gb|KU179098.1|Zika virus isolate JMB-185 nonstructural protein 5 gene, partial cds11821182100%0.099%KU179098.1Select seq gb|JN860885.1|Zika virus isolate FSS13025 polyprotein gene, partial cds11551155100%0.098%JN860885.1Select seq gb|EU545988.1|Zika virus polyprotein gene, complete cds11491149100%0.098%EU545988.1Select seq gb|KU681082.3|Zika virus isolate Zika virus/H.sapiens-tc/PHL/2012/CPC-0740, complete genome11381138100%0.098%KU681082.3Select seq gb|KJ873161.1|Zika virus isolate NC14-02042014-3220 nonstructural protein 5 gene, partial cds1134113493%0.099%KJ873161.1Select seq gb|HQ234499.1|Zika virus isolate P6-740 polyprotein gene, partial cds10161016100%0.094%HQ234499.1Select seq gb|KM851039.1|Zika virus strain SV0127/14 nonstructural protein 5 gene, partial cds92092077%0.099%KM851039.1Select seq gb|KM851038.1|Zika virus strain CPC-0740 nonstructural protein 5 gene, partial cds89389377%0.098%KM851038.1

26 February 2016CHP notified of sixth imported case of Zika Virus Infection in Mainland The Centre for Health Protection (CHP) of the Department of Health (DH) received notification today (February 26) of the sixth imported case of Zika Virus Infection in the Mainland from the National Health and Family Planning Commission and again urged the public, particularly pregnant women, those planning pregnancy and immunocompromised patients, to adopt strict anti-mosquito measures during travel. According to the health authority in the Mainland, the female patient aged 42 from Wenzhou, Zhejiang, works in Suriname. She departed Suriname for Zhejiang on February 21 and developed itchiness and skin rash during the journey. On February 23, she was admitted to hospital for isolation and management. The case was laboratory confirmed by the Health and Family Planning Commission of Zhejiang Province on February 26. At present, she is afebrile and still hospitalised for isolation and management. The patient did not pass through Hong Kong. "Routine health surveillance on the body temperature of inbound travellers at all boundary control points is ongoing. Suspected cases will be referred to healthcare facilities for follow-up. However, at present, around 70 to 80 per cent of infected people are asymptomatic and most can recover fully. Therefore, we again urge those arriving from Zika-affected areas to apply insect repellent for 14 days upon arrival to reduce the risk of transmission," the spokesman for the DH said. The DH has been closely working with the travel industry and stakeholders, especially agents operating tours in Zika-affected areas and personnel receiving travellers in those areas (particularly pregnant women), to regularly update them on the latest disease information and health advice. As long as there is international travel, there is always a risk of introduction of Zika virus to Hong Kong. As asymptomatic infection is very common and the potential vector, Aedes albopictus, is present locally, there is also risk of local spread in case Zika is introduced to Hong Kong. The public should pay special attention to the countries and areas with reported autochthonous Zika virus transmission or locally acquired infection and those with indication of viral circulation earlier announced by the World Health Organization (WHO). The DH has been maintaining close liaison with the WHO as well as overseas, neighbouring and Mainland health authorities to closely monitor the latest developments of Zika. Locally, no human Zika cases have been reported to the CHP to date. To prevent Zika Virus Infection, in addition to general anti-mosquito measures, the DH drew the public's attention to the special notes below: A. Travelling abroad * If going to areas with ongoing Zika transmission (affected areas), travellers, especially those with immune disorders or severe chronic illnesses, should arrange consultation with a doctor at least six weeks before the trip, and take extra preventive measures to avoid mosquito bites;* Those arriving from affected areas should apply insect repellent for 14 days upon arrival. If feeling unwell, e.g. having fever, they should seek medical advice as soon as possible, and provide travel details to a doctor; B. Pregnant women and those preparing for pregnancy * Pregnant women and those preparing for pregnancy should consider deferring their trip to affected areas. Those who must travel should seek medical advice from their doctor before the trip, adopt contraception if appropriate, strictly follow steps to avoid mosquito bites during the trip, and consult and reveal their travel history to their doctor if symptoms develop after the trip. Women preparing for pregnancy are advised to continue to adopt contraception for 28 days after returning from these areas; and C. Special notes for prevention of sexual transmission regarding potential adverse pregnancy outcomes * Pregnant women should not have sex with male partners who have travelled to areas with ongoing Zika virus transmission (affected areas), or else condoms should be used throughout the pregnancy;* Any male traveller returning from affected areas should:(i) abstain from sex with his pregnant partner, or else use condoms throughout the pregnancy; and(ii) use a condom for at least six months if his female partner may get pregnant. The public may visit the pages below for more disease information and health advice: * The CHP's Zika page (www.chp.gov.hk/en/view_content/43086.html);* The Zika page of the DH's Travel Health Service (www.travelhealth.gov.hk/english/popup/popup_zika.html);* The Outbound Travel Alert page of the Security Bureau (www.sb.gov.hk/eng/ota); and* Anti-mosquito precautions for women (www.fhs.gov.hk/english/health_info/woman/30014.html). Ends/Friday, February 26, 2016 http://www.chp.gov.hk/en/content/116/43601.html

Beijing: China has confirmed a new imported Zika case, bringing the total number to six, the authorities announced on Friday. The National Health and Family Planning Commission said that the patient, a 42-year-old woman from east Zhejiang province, was bitten by mosquitoes while working in Suriname in South America, Xinhua news agency reported. She returned to China on Sunday and developed an itchy rash but no fever on her way back, according to the commission. She was confirmed positive on Friday. The patient is in a good condition and recovering, the commission added. http://www.firstpost.com/world/china-confirms-sixth-zika-case-2645382.html