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New york has issued a press release on new actions - 11 confirmed Zika cases cited. http://www.governor.ny.gov/news/governor-cuomo-announces-additional-state-actions-combat-and-address-zika

Zika Virus – Feb. 4, 2016Texas has 10 cases of Zika virus disease. Nine are travelers who were infected abroad and diagnosed after they returned home. One case involves a Dallas County resident who had sexual contact with someone who acquired the Zika infection while traveling abroad. Case counts by county: Harris County – 7 Bexar County – 1 Dallas County – 2 Zika is primarily a mosquito-borne virus that can cause fever, rash, muscle and joint aches and pinkeye. Symptoms are usually mild, and most people exposed to Zika virus won’t develop any symptoms at all. There have been reports of microcephaly and other poor pregnancy outcomes in babies of mothers who were infected with Zika virus while pregnant. The Texas Department of State Health Services is encouraging people to follow travel precautions for regions and certain countries where Zika virus transmission is ongoing. DSHS recommends travelers avoid mosquito bites while abroad and for seven days after returning, in case they have been exposed to Zika virus. People can protect themselves from mosquito bites by: Wearing long-sleeved shirts and long pantsUsing EPA-registered insect repellentsUsing permethrin-treated clothing and gear Staying and sleeping in screened-in or air-conditioned roomsAvoiding or limiting outdoor activities during peak mosquito timesNote: Zika case data for Texas will be updated weekdays by 11 a.m. Texas Zika Virus DSHS News Releases CDC Zika Virus http://www.dshs.state.tx.us/news/updates.shtm

ZikaZika virus is transmitted to people by mosquitoes. The most common symptoms of Zika virus are fever, rash, joint pain, and conjunctivitis (red eyes). The illness is usually mild with symptoms lasting several days to a week. Severe disease requiring hospitalization is uncommon. Deaths are rare. Transmission Zika virus is spread to people primarily through the bite of an infected Aedes species mosquito. The mosquitoes typically lay eggs in and near standing water in things like buckets, bowls, animal dishes, flower pots, and vases. They are aggressive daytime biters, prefer to bite people, and live indoors and outdoors near people. Mosquitoes become infected when they feed on a person already infected with the virus. Infected mosquitoes can then spread the virus to other people through bites. A mother already infected with Zika virus near the time of delivery can pass on the virus to her newborn around the time of birth. It is possible that Zika virus could be passed from mother to fetus during pregnancy. Zika is an emerging virus. As of January 2016, there were no reports of infants getting Zika virus through breastfeeding. Because of the benefits of breastfeeding, mothers are encouraged to breastfeed even in areas where Zika virus is found. As of January 2016, there was one report of possible spread of Zika virus through blood transfusion and one report of possible spread through sexual contact. Symptoms About 1 in 5 people infected with Zika virus become ill (i.e., develop Zika). The most common symptoms of Zika virus are fever, rash, joint pain, and conjunctivitis (red eyes). Other common symptoms include muscle pain and headache. The illness is usually mild with symptoms lasting for several days to a week. Severe disease requiring hospitalization is uncommon. Deaths are rare. See your healthcare provider if you develop the symptoms and have visited an area where Zika virus is present. If you have recently traveled, tell your healthcare provider when and where. Treatment No vaccine or medications are available to prevent or treat Zika infections. Treat the symptoms: Get plenty of rest. Drink fluids to prevent dehydration. Take medicines, such as acetaminophen or paracetamol, to relieve fever and pain. Aspirin and other non-steroidal anti-inflammatory drugs (NSAIDs), like ibuprofen and naproxen, should be avoided until dengue can be ruled out to reduce the risk of hemorrhage. If you are taking medicine for another medical condition, talk to your healthcare provider before taking additional medication. If you have Zika virus, avoid mosquito bites for the first week of your illness. During the first week of infection, Zika virus can be found in the blood and passed from an infected person to another mosquito through mosquito bites. An infected mosquito can then spread the virus to other people. Prevention DCHHS recommends everyone use the 4Ds to reduce the chance of being bitten by a mosquito. DEET All Day, Every Day: Whenever you’re outside, use insect repellents that contain DEET or other EPA approved repellents and follow instructions. DRESS: Wear long, loose, and light-colored clothing outside. DRAIN: Remove all standing water in and around your home. DUSK & DAWN: Limit outdoor activities during dusk and dawn hours when mosquitoes are most active. Travelers can protect themselves further by doing the following: Choose a hotel or lodging with air conditioning or screens on windows or doors. Sleep under a mosquito bed net if you are outside or in a room that is not well-screened. Sexual partners can protect each other by using condoms. Pregnant women and women trying to get pregnant can protect themselves further by taking the following precautions: Pregnant women in any trimester should consider postponing travel to the areas where Zika virus transmission is ongoing. Pregnant women who do travel to one of these areas should talk to their doctor or other healthcare provider first and strictly follow steps to avoid mosquito bites during the trip. Women trying to become pregnant or who are thinking about becoming pregnant should consult with their healthcare provider before traveling to these areas and strictly follow steps to prevent mosquito bites during the trip. Downloadable Information DCHHS Zika Virus Brochure in English en Español DCHHS Zika Virus Fact Sheet in Various Languages AmharicNepaliArabicRussianEnglishSpanishFarsiSwahiliHindiUrdu DCHHS Side-by-Side Comparison of Chikungunya, Dengue and Zika More information DCHHS Health Advisory: Sexual Transmission of Zika Virus CDC: Countries and territories with active Zika virus transmission CDC Interim Travel Guidance 1/26/2016 CDC MMWR Interim Guidelines for the Evaluation and Testing of Infants with Possible Congenital Zika Virus Infections 1/26/2016 CDC Interim Travel Guidance 1/22/2016 CDC Interim Travel Guidance 1/15/2016 For Providers: Zika Virus Specimen Submissions DCHHS Zika Clinical Specimen Submission and Testing Form DCHHS Instructions for Healthcare Providers for Submission of Specimens for Zika Virus Testing * There are currently no reports of Zika virus being locally-transmitted by mosquitoes in Dallas County. However, imported cases make local spread by mosquitoes possible because the mosquitoes that can transmit the virus are found locally. For general questions or for more information about Dallas County Health and Human Services, please email Director Zachary Thompson at: [email protected] Zachary S. Thompson DirectorChristopher Perkins, D.O., M.P.H. Medical Director / Health Authority Last Updated: 02/04/2016http://www.dallascounty.org/department/hhs/zika.html

DCHHS Provides Update on Zika Virus Cases DALLAS (Feb. 4, 2016) – Dallas County Health and Human Services (DCHHS) has completed the initial public health investigation on the two Zika cases reported Feb. 2. Both patients have recovered fully. As part of the public health follow-up, the patients have been advised to follow up with their physician. DCHHS conducted mosquito surveillance in the area of the patients’ residence and did not identify any mosquito/vector activity. See the DCHHS health advisory for more information.DCHHS does not have further updates on the two cases reported Feb. 2. DCHHS is awaiting four Zika virus specimen results from the Centers for Disease Control and Prevention. For information on Zika virus, go to the DCHHS website. # For additional information, contact: Erikka D. Neroes, Public Information [email protected] 214.819.6329 (office) 214.394.8109 (cell) Zachary Thompson, Director 214.755.9299 (cell)

DCHHS update on 2 Zika confirmed cases cites four more suspect cases.

DCHHS Provides Update on Zika Virus Cases DALLAS (Feb. 4, 2016) – Dallas County Health and Human Services (DCHHS) has completed the initial public health investigation on the two Zika cases reported Feb. 2. Both patients have recovered fully. As part of the public health follow-up, the patients have been advised to follow up with their physician. DCHHS conducted mosquito surveillance in the area of the patients’ residence and did not identify any mosquito/vector activity. See the DCHHS health advisory for more information.DCHHS does not have further updates on the two cases reported Feb. 2. DCHHS is awaiting four Zika virus specimen results from the Centers for Disease Control and Prevention. For information on Zika virus, go to the DCHHS website.

DCHHS Provides Update on Zika Virus Cases DALLAS (Feb. 4, 2016) – Dallas County Health and Human Services (DCHHS) has completed the initial public health investigation on the two Zika cases reported Feb. 2. Both patients have recovered fully. As part of the public health follow-up, the patients have been advised to follow up with their physician. DCHHS conducted mosquito surveillance in the area of the patients’ residence and did not identify any mosquito/vector activity. See the DCHHS health advisory for more information.DCHHS does not have further updates on the two cases reported Feb. 2. DCHHS is awaiting four Zika virus specimen results from the Centers for Disease Control and Prevention. For information on Zika virus, go to the DCHHS website.

DCHHS Provides Update on Zika Virus Cases DALLAS (Feb. 4, 2016) – Dallas County Health and Human Services (DCHHS) has completed the initial public health investigation on the two Zika cases reported Feb. 2. Both patients have recovered fully. As part of the public health follow-up, the patients have been advised to follow up with their physician. DCHHS conducted mosquito surveillance in the area of the patients’ residence and did not identify any mosquito/vector activity. See the DCHHS health advisory for more information.DCHHS does not have further updates on the two cases reported Feb. 2. DCHHS is awaiting four Zika virus specimen results from the Centers for Disease Control and Prevention. For information on Zika virus, go to the DCHHS website.

Spain Confirms Zika Virus In Pregnant Woman16:49, UK, Thursday 04 February 2016 Share on TwitterShare on FacebookShare on Google+Share by emailA pregnant woman in Spain who had travelled to Colombia has the Zika virus, health officials say. Colombia is one of a number of South America countries which has been affected by the outbreak. The woman, from Catalunya, was having clinical tests but she was described as being in good health and has not been admitted to hospital. More follows... http://news.sky.com/story/1636105/spain-confirms-zika-virus-in-pregnant-woman

Spain confirms case of Zika virus in a pregnant woman - the first in Europe This breaking news story is being updated and more details will be published shortly. Please refresh the page for the fullest version. If you want to receive Breaking News alerts via email, or on a smartphone or tablet via the BBC News App then details on how to do so are available on this help page. You can also follow @BBCBreaking on Twitter to get the latest alerts. http://www.bbc.com/news/world-europe-35490524?ns_mchannel=social&ns_campaign=bbc_breaking&ns_source=twitter&ns_linkname=news_central

Detected the first case of zika in a pregnant woman in Spain This is a pregnant woman in the second trimester of pregnancy who developed symptoms after traveling to ColombiaThis case has been registered in Catalonia and are already seven detected in SpainMiguel Huertas Date 04/02/2016 at 17:19 TAGSMiguel HuertasMinistry of Health10 THE AUTHOROther itemsRELATEDNEWSThese are the recommendations of Health to contract the no traveler zikaNEWSWHO global emergency decrees virus zikaNEWSZika without bordersPhotography of January 30, 2016, the mosquito Aedes Aegypti in San José (Costa Rica). The Ministry of Health, Social Services and Equality reported Thursday in a press release of the first case in Spain "of a pregnant woman who developed symptoms" of having contracted the zika "after traveling to Colombia". The patient was diagnosed in Catalonia, "is in the second third of pregnancy and are under medical supervision," according to health. So far, seven people have been diagnosed with infection with this virus in our country, all of them "after visiting affected countries, what is imported cases , "says the ministry. Three of these patients would be in Catalonia, including the pregnant-woman, two in Murcia and two in Castilla y León. All of them are in good health and their situation "does not resist gravity" .The cases of Zika discovered in Spain viruses enter "so far" within the provisions of epidemiologists and "pose no risk of spreading the virus our country "and that the ministry insists," it is imported cases. "http://www.infolibre.es/noticias/politica/2016/02/04/detectado_primer_caso_zika_una_mujer_embarazada_espana_44331_1012.html

First Zika confirmed pregnant case in Spain.

New link between Zika virus and microcephaly is found in BrazilKATIE WORTH, FRONTLINEFRONTLINE-Columbia Tow Journalism Fellow FOLLOW 79 EMAILBY KATIE WORTH, FRONTLINE February 4, 2016 at 7:14 AM ESTDr. Natalia Brin examines a 2-month-old with suspected microcephaly in Brazil. Photo by Katie Worth/FRONTLINE Editor’s note: This report is part of a special series with Katie Worth, who is embedded in Brazil, and our partners at PBS Frontline/WGBH. RECIFE, Brazil — Researchers in the state of Pernambuco, home to a third of Brazil’s suspected cases of infant microcephaly, said on Wednesday that they have identified some of the clearest evidence yet of a direct link between the debilitating birth defect and the Zika virus. Researchers here tested the spinal fluid of 12 babies with microcephaly, all of whom were born to mothers who reported having symptoms of Zika early in their pregnancies. In all 12 cases, the researchers found evidence of Zika — results they described as stunning. “I was so surprised,” said Marli Tenório, an infectious disease expert at the Aggeu Magalhães Research Center. “Everybody wants to say, ‘It’s not Zika, it’s not Zika.’ I saw this and thought, ‘Wow, it’s Zika!’” In a press conference at the Pernambuco Health Department, Secretary of Vigilance and Health Luciana Albuquerque cautioned that “this is not a scientific study,” noting that the results do not indicate a definitive causal link. “But it’s a very important suggestion of the link,” she said. “Everybody wants to say, ‘It’s not Zika, it’s not Zika.’ I saw this and thought, ‘Wow, it’s Zika!’”As the Zika virus has spread to more than 20 countries in the Americas, researchers in Brazil have been on the hunt for the cause of the recent wave of microcephaly, a birth defect in which babies are born with small heads, underdeveloped brains and the prospect of lifelong developmental delays. Health officials in Pernambuco say that until last year, the state saw no more than a dozen microcephaly cases annually. But beginning in late August, babies in Pernambuco began displaying symptoms by the dozens, and then by the hundreds. As of Wednesday, Brazil’s health authorities had logged 4,783 cases of suspected microcephaly since the outbreak began. The majority of those are likely false positives: All babies with a head circumference of less than 32 centimeters are flagged as a suspected case, but many are born with small heads for other reasons. Of the 1,313 cases the government has investigated so far, 404 were confirmed to have microcephaly. The diagnosis was rejected in the remaining cases. Still, even the confirmed figures represent a surge in the incidence of microcephaly over prior years, particularly in northeastern Brazil where most cases have been concentrated. “We used to have 10 cases a year in Pernambuco. Then in August we started having 10 cases a week,” said Dr. Angela Rocha, a pediatric infectious disease specialist at Recife’s largest public hospital. A municipal worker sprays insecticide at the neighborhood of Afogados in Recife, Brazil, February 2, 2016. The operation is part of the city’s effort to prevent the spread of Zika’s vector, the Aedes aegypti mosquito, according to a statement from Municipal Health Secretary. Photo by Ueslei Marcelino/Reuters In October, health officials began investigating whether the precipitous rise in microcephaly was linked to a mysterious outbreak of Zika in Brazil. The mosquito-borne disease had been floating around Africa and Asia for decades, but it attracted little attention from health officials because its obvious symptoms were relatively benign and easily confused with other illnesses. In symptomatic cases, Zika can lead to a rash, a headache, red eyes, swollen joints and a light fever. Others contract the disease but never display symptoms. Zika’s mosquito-born cousins, dengue and chikungunya, are both far more debilitating and painful. Zika is believed to have arrived in Brazil in late 2014, but it did so with such little fanfare that health officials here didn’t confirm its presence until May 2015. By then, it is thought to have infected at least tens of thousands of people. Those figures are only estimates, though, since health officials hadn’t collected data about it. In Pernambuco, for example, the reported Zika infections had been lumped in with reported dengue figures. The outbreak took on a new urgency in October, when researchers began to wonder whether Zika may be behind the rise in suspected microcephaly cases. But definitive evidence of a link has been elusive. RELATED CONTENTMosquito breeding grounds are front line in fight against ZikaDallas reports first case of sexually transmitted Zika virus, CDC to issue guidance The earliest indication came when microcephaly began to appear in the same areas where Zika had landed months earlier. Brazilian researchers later found traces of the virus in the amniotic fluid and the brain tissue of a small number of microcephaly babies. The Centers for Disease Control and Prevention also found Zika virus in the brains of two deceased newborns with the condition, as well as in the placentas of two women who had miscarriages. In search of better evidence, Tenório and several colleagues flew to Belém in January to meet with officials from the CDC. The agency had developed a test that could determine if a baby had been infected with the Zika virus by looking for a specific antibody in the baby’s cerebral-spinal fluid. This is not a new method of testing, but it was being newly applied to Zika. The test is not yet commercially available, but the CDC explained the methodology to Tenório and her colleagues, and upon their return, they tested samples of 12 babies whose spinal fluid had been collected shortly after birth. They all tested positive. This test works better than others because it is looking for an antibody called immunoglobulin M, the largest antibody humans produce. It is too large to pass from mother to child, so researchers can be confident that it is an antibody produced by the baby — and can therefore infer that the baby was infected with Zika while en utero. Its presence in the cerebrospinal fluid is key for two additional reasons, Tenório said. It indicates the virus is making its way into the nervous system, and the baby’s immune system is battling it there. And second, while immunoglobulin M disappears from the blood stream within weeks of an infection, it remains present in the cerebrospinal fluid for months or longer. This means the antibody can be detected at birth. While her colleagues are launching a controlled study to further investigate the Zika-microcephaly link in babies, Tenório is using the CDC test for 28 more infants with suspected or confirmed microcephaly. She said she hopes to have the results by Friday, before most work in Brazil stops for the national Carnival celebrations. Katie Worth is Frontline’s inaugural PBS Frontline-Columbia Tow journalism fellow. Katie Worth, FRONTLINEKatie Worth is FRONTLINE's inaugural FRONTLINE-Columbia Tow Journalism Fellow. @katieworthhttp://www.pbs.org/newshour/updates/new-link-between-zika-virus-and-microcephaly-is-found-in-brazil/

SES presents new study that strengthens the relationship between the zika and microcephaly1,447 cases of microcephaly were reported from 1/08/15 to 30/1/16. Of this total, 543 probable cases and 153 confirmed cases Published in 02.03.2016 at 17:36 Radio Journal Photo: Isabela Days / Radio Journal Representatives of the State Department of Health, infectious disease specialists and members of the Epidemiological Surveillance departments and Women's Health met on the afternoon of Wednesday (3) to present the microcephaly numbers in Pernambuco. According to the information submitted, were notified 1,447 cases of microcephaly of August 1 last year to January 30, 2016. Of this total, there are 543 probable cases and 153 confirmed cases. The executive secretary of Health Surveillance, Luciana Albuquerque, said a new test to identify the zika virus in infants with microcephaly. According to the secretary, 12 cases were investigated and confirmed the presence of the virus, which strengthens the virus compared with microcephaly. "Although these 12 children are not representative of a total of 1,400 children we have reported, was an important discovery was important evidence that strengthens the virus zika's relationship with microcephaly," he said. The researcher of Haggai Magalhães Laboratory, Marli Tenorio explains how the test is done. "In the case of the serological testing, we do in the liquid and reap the backbone, we seek this liquid an antibody that would be the child's response to infection by this virus," he explained. "If we try this antibody in the liquid column, the backbone, have some tests that we use the antigen zika and there we detect whether the antibody is present or not," he added, also stating that if it is found antibody in the liquid, means that the virus grew and was present in the child's brain. The material for the exams was provided by the US Disease Control Center. Also according to the department, 28 new samples are being tested. On Monday (1), the World Health Organization (WHO) declared international emergency by microcephaly. In Dallas, in the United States, was detected the first place in case of virus transmission in the country, according to the agency, the contamination was through sexual intercourse with a person who traveled to Venezuela. http://m.radiojornal.ne10.uol.com.br/noticia/2016/02/03/ses-apresenta-novo-estudo-que-reforca-relacao-entre-o-zika-e-a-microcefalia--44684

PE identifies the 1st time presence of zika in babies with microcephaly 02.03.16 at 20:06 FolhapressTextos, fotos, artes e vídeos da odiario.com estão protegidos pela legislação brasileira sobre direito autoral. Não reproduza o conteúdo em qualquer meio de comunicação, eletrônico ou impresso, sem autorização de odiario.com. As regras têm como objetivo proteger o investimento que odiario.com faz na qualidade de seu jornalismo. Para compartilhar este conteúdo, utilize o link:http://maringa.odiario.com/geral/2016/02/pe-identifica-pela-1a-vez-presenca-de-zika-em-bebes-com-microcefalia/2078301/Textos, fotos, artes e vídeos da odiario.com estão protegidos pela legislação brasileira sobre direito autoral. Não reproduza o conteúdo em qualquer meio de comunicação, eletrônico ou impresso, sem autorização de odiario.com. As regras têm como objetivo proteger o investimento que odiario.com faz na qualidade de seu jornalismo. Para compartilhar este conteúdo, utilize o link:http://maringa.odiario.com/geral/2016/02/pe-identifica-pela-1a-vez-presenca-de-zika-em-bebes-com-microcefalia/2078301/Textos, fotos, artes e vídeos da odiario.com estão protegidos pela legislação brasileira sobre direito autoral. Não reproduza o conteúdo em qualquer meio de comunicação, eletrônico ou impresso, sem autorização de odiario.com. As regras têm como objetivo proteger o investimento que odiario.com faz na qualidade de seu jornalismo. Para compartilhar este conteúdo, utilize o link:http://maringa.odiario.com/geral/2016/02/pe-identifica-pela-1a-vez-presenca-de-zika-em-bebes-com-microcefalia/2078301/Textos, fotos, artes e vídeos da odiario.com estão protegidos pela legislação brasileira sobre direito autoral. Não reproduza o conteúdo em qualquer meio de comunicação, eletrônico ou impresso, sem autorização de odiario.com. As regras têm como objetivo proteger o investimento que odiario.com faz na qualidade de seu jornalismo. Para compartilhar este conteúdo, utilize o link:http://maringa.odiario.com/geral/2016/02/pe-identifica-pela-1a-vez-presenca-de-zika-em-bebes-com-microcefalia/2078301/Textos, fotos, artes e vídeos da odiario.com estão protegidos pela legislação brasileira sobre direito autoral. Não reproduza o conteúdo em qualquer meio de comunicação, eletrônico ou impresso, sem autorização de odiario.com. As regras têm como objetivo proteger o investimento que odiario.com faz na qualidade de seu jornalismo. Para compartilhar este conteúdo, utilize o link:http://maringa.odiario.com/geral/2016/02/pe-identifica-pela-1a-vez-presenca-de-zika-em-bebes-com-microcefalia/2078301/KLEBER NUNES RECIFE, PE (Folhapress) - The Center for Aggeu Magellan, from Fiocruz, and the Pernambuco Department of Health were able to identify for the first time the presence of zika virus in babies with microcephaly in the state. Samples of CSF (cerebrospinal fluid) of 12 infants with malformations revealed in all of them the existence of recent antibodies against the virus, which proves that the fetuses were infected in the womb. For specialists, the result reinforces the evidence that the virus causes microcephaly zika a malformation of the brain that affects child development. The tests were performed with reagents granted by CDC (disease control centers), the United States. "In the liquid that was extracted from the marrow of these babies find the IgM, which is unable to overcome the placenta antibody. This leads us to see that the own baby produced the antibody to have been infected by zika after her mother was bitten by Aedes aegypti said Marli Tenorio, a researcher at Aggeu Magellan. Despite being only 12 confirmed cases in a universe of 1,447 microcephaly notifications in the state, the executive secretary of Health Surveillance of Pernambuco, Luciana Albuquerque, says the result shows advances in research. "We will continue doing research for CSF analysis. It is not yet unscientific [because need the confirmation of more cases], but brings very strong evidence of zika correlation with microcephaly. We have 28 more samples are being analyzed, and next week we will have the results, "said Albuquerque. The PCR test, recommended by the Ministry of Health protocol, can only find the virus in the body between the fifth and seventh day of infection blood, which makes its narrower range. So far, cases of microcephaly have been confirmed by the measurement of head circumference less than 32 cm at birth, as determined by the wHO, and the presence of calcifications in the brain detected by through imaging studies. Within these criteria, Pernambuco accounts August until this Wednesday (3) 153 cases of malformation. Two CDC researchers were in Brazil in January to give training to Brazilian specialists, who are now developing serology zika the Instituto Evandro Chagas in Belém. for now, the reagents are not commercially available in Brazil, according to Marli Tenorio researcher. This means that you still can not use this method on a large scale to confirm the relationship between zika and microcephaly. Luciana Albuquerque said the CDC said he was willing to provide, through the Ministry of Health, the reagents for Brazil.The ministry was contacted but did not respond to 19h. BALANCE Since the notification of cases of pregnant women with rashes (red spots on the body) became mandatory on December 2, 2015, until January 30, 2016, 88 municipalities of Pernambuco registered 994 cases. Of this total, ten pregnant women have had confirmation that the fetus has microcephaly. In January, Pernambuco recorded 7,120 dengue suspected, 190% more than in the same period last year.Out of this, 723 were confirmed nine deaths are under investigation. Referring to the virus zika, the State notified 1,068 suspected cases in the past month, with 14 confirmations. Of chikungunya fever were reported 1,507 suspected cases in 87 municipalities. Of these, one hundred were confirmed. There is a death under investigation. The same Aedes aegypti mosquito transmits dengue, chikungunya fever and virus zika. https://www.bemparana.com.br/noticia/427410/pe-identifica-pela-1a-vez-presenca-de-zika-em-bebes-com-microcefalia

02/03/2016 17h21 - Updated 02/03/2016 20:50 Pernambuco confirms 12 cases of microcephaly linked to zika virusUntil the 30th of January, 153 babies have been confirmed with the malformation. State has 1,447 cases reported since the 1st of August 2015. G1 PE FACEBOOKPernambuco confirms 12 cases of microcephaly associated with zika virus (Photo: Arthur Ferraz / G1)Pernambuco has 12 confirmed cases of microcephaly related zika virus. The data were transferred by the state Health Department on Wednesday (3), in a press conference. According to the latest report, by the 30th of January, 153 babies had a confirmed diagnosis of malformation through imaging tests. The diagnosis of microcephaly linked to zika was done through an alternative examination, serology, which seeks to detect the presence of a specific antibody in Net Cervicofacial Oblongata (LCR), the child's cord. The analyzes were collected by the research center Aggeu Magalhães, of the Oswaldo Cruz Foundation. MICROCEPHALYHigh of cases concernedemergencywhich is microcephalyrelationship with zika virustips from Dr. ana"The ideal is to detect the virus, either by insulation or by the demand of the virus genome. The other possibility is for this examination, looking for IgM antibody, which does not cross the placenta. And these 12 children, found that antibody for microcephaly, "said Marli Tenorio researcher. Also according to the scientist, the number of related cases is still not enough to prove that the zika can cause microcephaly in babies and inquiries continue. "We are testing 28 more samples. You have to associate the laboratory findings to the clinic", explained the researcher.Of the 12 children, 11 were born in Imip and the Hospital Barão de Lucena, both in Recife.According to the executive secretary of Health Surveillance, Luciana Albuquerque, it was necessary to be done the alternate exam because others can only detect the parasite in cases most recent. "What we have available is the PCR, which looks for the virus genome. The problem is that it can only make the diagnosis in very recent cases, and how the children were infected during pregnancy, in all of them, the result was negative, "he said. For secretary, for now, only serology, it was possible to detect the presence of the virus more accurately. "There is evidence of scientific study, but now we come close to discovering the relationship between zika and microcephaly," he said. Since August 1, 1447 cases of babies with microcephaly have been reported in Pernambuco. Of these, 153 were confirmed by imaging and other 135 were discharged by doctors. Were also recorded 12 deaths of children with microcephaly, which does not mean that the defect was the cause of the deaths. Of the total notified babies, 543 (37.5%) meet the criteria of the World Health Organization (WHO) for microcephaly , which identifies the malformation in babies with head circumference equal to or less than 32 centimeters.investments Since the World health Organization (wHO) has classified the spread of zika virus as international public health emergency case , the secretary expects further investments in research in Pernambuco. "When the WHO launches an emergency declaration opens up new possibilities for investment in vaccines. There will be more cooperation with Brazil. So the expectation is good," said the secretary. In relation to the suspicion that the zika virus can be transmitted sexually , Luciana Albuquerque did not rule out the idea of investigating the evidence in the state. "It is likely that there is research on this, but now we will focus on children and pregnant women. The United States is already investigating," he reiterated. Dengue, chikungunya and zika viruses According to the latest bulletin from the Health Department, between 3 and 23 January, were reported 7,120 cases of dengue in the state, which represents an increase of 90% compared to the same period last year. Also according to the SES, nine deaths are being investigated and 142 municipalities had reports of the disease. In the same period, there were 1,507 notifications of chikugunya. Of this total, 450 cases were confirmed, and 589 discarded. In relation to zika virus, provided that the notifications of the disease became mandatory, on December 10, 2015, there were 1,386 reported cases. Also last year, 14 cases were confirmed. Twelve were discarded. http://g1.globo.com/pernambuco/noticia/2016/02/pernambuco-confirma-12-casos-de-microcefalia-ligados-ao-virus-zika.html

tests confirm zika in 12 childrentest conducted in Pernambuco, in partnership with the United States, found antibody that signals the infection zika By: Alice de Souza - Diario de Pernambuco Published: 02/04/2016 07:27 Updated: 02/04/2016 07:29 Pernambuco currently has 1,447 reported cases of microcephaly. It is the leading state in detections. Photo: Ricardo Peu / Esp. DPSerological examinations in the Cerebrospinal Fluid samples (CSF) of 12 children Pernambuco with microcephaly - malformation altering brain development - identified the presence of antibody that signals the infection zika virus. The tests were conducted by research center Aggeu Magellan with reagents sent by the Disease Control Center (CDC) in the United States. Another 28 babies are being analyzed and the results should come out by the end of the week. Pernambuco currently has 1,447 reported cases of microcephaly and 153 confirmed. The tests were conducted after a meeting of Pernambuco and US researchers at the Instituto Evandro Chagas, Pará in January. It was used a methodology not yet available in the country, but that is under development here, to analyze samples of 11 children born in Imip and the Baron de Lucena. All of them showed the presence of IgM molecule in the liquid, which is located in the bone marrow."Every time we find a positive IgM in newborn means that he suffered infection and produced antibodies," explained the sector's chief infectious diseases at the University Hospital Oswaldo Cruz (HUOC), Angela Rocha. "If you find the IgM is indicative that the virus replicated in the central nervous system," the virologist and researcher at Aggeu Magellan Marli Tenorio. The IgM can stay in the blood for about two months. CSF, six months to a year, experts estimate. Babies born analyzed all last year. Seven of them have already been notified, the other five to the Department of Health is actively seeking to find. "It is not scientific evidence, but the findings greatly strengthen the relationship of microcephaly with the virus zika," said the executive secretary of Health Surveillance, Luciana Albuquerque. Numbers The arboviruses remain growing in Pernambuco. Dengue jumped 190% last week, compared to the same period last year. The state has 7100 reported cases. The zika has 1,086 cases reported this year. SES does not rule out that the data are duplicated - for more than an arbovirus - and will review notifications. After the carnival, health workers will begin work in raising public awareness. An application was created to transmit real-time data collected by them to the Secretariat. http://www.diariodepernambuco.com.br/app/noticia/vida-urbana/2016/02/04/interna_vidaurbana,625397/exames-confirmam-zika-em-12-criancas.shtml

PE identifies the 1st time presence of zika in babies with microcephalyKLEBER NUNES REEF 02.03.2016 19:45Share315 More optionsADVERTISING The Centre Aggeu Magellan, from Fiocruz, and the Pernambuco Department of Health were able to identify for the first time the presence of zika virus in infants with microcephaly in the state. Samples of CSF (cerebrospinal fluid) of 12 infants with malformations revealed in all of them the existence of recent antibodies against the virus, which proves that the fetuses were infected in the womb. For specialists, the result reinforces the evidence that the virus causes microcephaly zika a malformation of the brain that affects child development.The tests were performed with reagents granted by CDC (disease control centers), the United States. "In the liquid that was extracted from the marrow of these babies find the IgM, which is unable to overcome the placenta antibody. This leads us to see that the own baby produced the antibody to have been infected by zika after her mother was bitten by Aedes aegypti said Marli Tenorio, a researcher at Aggeu Magellan. Despite being only 12 confirmed cases in a universe of 1,447 microcephaly notifications in the state, the executive secretary of Health Surveillance of Pernambuco, Luciana Albuquerque, says the result shows advances in research. "We will continue doing research for CSF analysis. There is still no scientific [because need the confirmation of more cases], but brings very strong evidence of correlation zika with microcephaly. We have 28 more samples are being analyzed, and next week we will have the results, "said Albuquerque. The PCR test, recommended by the Ministry of Health protocol, can only find the virus in the body between the fifth and seventh day of infection in the blood, which makes its narrower range. So far, cases of microcephaly have been confirmed by the measurement of head circumference less than 32 cm at birth, as determined by the WHO, and the presence of calcifications in the brain, detected by imaging. Within these criteria, Pernambuco accounts August until this Wednesday (3) 153 cases of the malformation. Two CDC researchers were in Brazil in January to give training to Brazilian specialists, who are now developing the serology zika the Evandro Chagas Institute in Belém. For now, the reagents are not commercially available in Brazil, according to Marli Tenorio researcher . This means that you still can not use this method on a large scale to confirm the relationship between zika and microcephaly. Luciana Albuquerque said the CDC said he was willing to provide, through the Ministry of Health, the reagents for Brazil. The ministry was contacted but did not respond to 19h. BALANCE SHEET Since the notification of cases of pregnant women with rashes (red spots on the body) became mandatory on December 2, 2015, until January 30, 2016, 88 municipalities of Pernambuco registered 994 cases. Of this total, ten pregnant women have had confirmation that the fetus has microcephaly. In January, Pernambuco recorded 7,120 dengue suspected, 190% more than in the same period last year. Out of this, 723 were confirmed nine deaths are under investigation. Referring to the virus zika, the State notified 1,068 suspected cases in the past month, with 14 confirmations. Fever chikungunya were reported 1,507 suspected cases in 87 municipalities.Of these, one hundred were confirmed. There is a death under investigation. The same mosquito Aedes aegypti transmits dengue, chikungunya fever and virus zika. http://www1.folha.uol.com.br/cotidiano/2016/02/1736681-pe-identifica-pela-1-vez-presenca-de-zika-em-bebes-com-microcefalia.shtml

New Link Between Zika and Microcephaly Is Found in BrazilSHARE / COMMENTSFEBRUARY 3, 2016 /by KATIE WORTH Tow Journalism Fellow, FRONTLINE/Columbia Journalism School Fellowships Dr. Natalia Brin examines a 2-month-old with suspected microcephaly in Brazil. (Katie Worth/FRONTLINE) RECIFE, Brazil — Researchers in the state of Pernambuco, home to a third of Brazil’s suspected cases of infant microcephaly, said on Wednesday that they have identified some of the clearest evidence yet of a direct link between the debilitating birth defect and the Zika virus. Researchers here tested the spinal fluid of 12 babies with microcephaly, all of whom were born to mothers who reported having symptoms of Zika early in their pregnancies. In all 12 cases, the researchers found evidence of Zika — results they described as stunning. “I was so surprised,” said Marli Tenório, an infectious disease expert at the Aggeu Magalhães Research Center. “Everybody wants to say, ‘It’s not Zika, it’s not Zika.’ I saw this and thought, ‘Wow, it’s Zika!'” In a press conference at the Pernambuco Health Department, Secretary of Vigilance and Health Luciana Albuquerque cautioned that “this is not a scientific study,” noting that the results do not indicate a definitive causal link. “But it’s a very important suggestion of the link,” she said. As the Zika virus has spread to more than 20 countries in the Americas, researchers in Brazil have been on the hunt for the cause of the recent wave of microcephaly, a birth defect in which babies are born with small heads, underdeveloped brains and the prospect of lifelong developmental delays. Health officials in Pernambuco say that until last year, the state saw no more than a dozen microcephaly cases annually. But beginning in late August, babies in Pernambuco began displaying symptoms by the dozens, and then by the hundreds. As of Wednesday, Brazil’s health authorities had logged 4,783 cases of suspected microcephaly since the outbreak began. The majority of those are likely false positives: All babies with a head circumference of less than 32 centimeters are flagged as a suspected case, but many are born with small heads for other reasons. Of the 1,313 cases the government has investigated so far, 404 were confirmed to have microcephaly. The diagnosis was rejected in the remaining cases. Still, even the confirmed figures represent a surge in the incidence of microcephaly over prior years, particularly in northeastern Brazil where most cases have been concentrated. “We used to have 10 cases a year in Pernambuco. Then in August we started having 10 cases a week,” said Dr. Angela Rocha, a pediatric infectious disease specialist at Recife’s largest public hospital. In October, health officials began investigating whether the precipitous rise in microcephaly was linked to a mysterious outbreak of Zika in Brazil. The mosquito-born disease had been floating around Africa and Asia for decades, but it attracted little attention from health officials because its obvious symptoms were relatively benign and easily confused with other illnesses. In symptomatic cases, Zika can lead to a rash, a headache, red eyes, swollen joints and a light fever. Others contract the disease but never display symptoms. Zika’s mosquito-born cousins, dengue and chikungunya, are both far more debilitating and painful. Zika is believed to have arrived in Brazil in late 2014, but it did so with such little fanfare that health officials here didn’t confirm its presence until May 2015. By then, it is thought to have infected at least tens of thousands of people. Those figures are only estimates, though, since health officials hadn’t collected data about it. In Pernambuco, for example, the reported Zika infections had been lumped in with reported dengue figures. The outbreak took on a new urgency in October, when researchers began to wonder whether Zika may be behind the rise in suspected microcephaly cases. But definitive evidence of a link has been elusive. The earliest indication came when microcephaly began to appear in the same areas where Zika had landed months earlier. Brazilian researchers later found traces of the virus in the amniotic fluid and the brain tissue of a small number of microcephaly babies. The Centers for Disease Control and Prevention also found Zika virus in the brains of two deceased newborns with the condition, as well as in the placentas of two women who had miscarriages. In search of better evidence, Tenório and several colleagues flew to Belém in January to meet with officials from the CDC. The agency had developed a test that could determine if a baby had been infected with the Zika virus by looking for a specific antibody in the baby’s cerebral-spinal fluid. This is not a new method of testing, but it was being newly applied to Zika. The test is not yet commercially available, but the CDC explained the methodology to Tenório and her colleagues, and upon their return, they tested samples of 12 babies whose spinal fluid had been collected shortly after birth. They all tested positive. This test works better than others because it is looking for an antibody called immunoglobulin M, the largest antibody humans produce. It is too large to pass from mother to child, so researchers can be confident that it is an antibody produced by the baby — and can therefore infer that the baby was infected with Zika while en utero. Its presence in the cerebrospinal fluid is key for two additional reasons, Tenório said. It indicates the virus is making its way into the nervous system, and the baby’s immune system is battling it there. And second, while immunoglobulin M disappears from the blood stream within weeks of an infection, it remains present in the cerebrospinal fluid for months or longer. This means the antibody can be detected at birth. While her colleagues are launching a controlled study to further investigate the Zika-microcephaly link in babies, Tenório is using the CDC test for 28 more infants with suspected or confirmed microcephaly. She said she hopes to have the results by Friday, before most work in Brazil stops for the national Carnival celebrations.

12 of 12 Brazil microcephaly babies had Zika IgM antibodies in spinal fluid. http://www.pbs.org/wgbh/frontline/article/new-link-between-zika-and-microcephaly-is-found-in-brazil/

Sequences producing significant alignments:Select:AllNone Selected:0 AlignmentsDownloadGenBankGraphicsDistance tree of resultsShow/hide columns of the table presenting sequences producing significant alignmentsSequences producing significant alignments:Select for downloading or viewing reportsDescriptionMax scoreTotal scoreQuery coverE valueIdentAccessionSelect seq gb|KU365778.1|Zika virus strain BeH819015 polyprotein gene, complete cds1934619346100%0.0100%KU365778.1Select seq gb|KU365779.1|Zika virus strain BeH819966 polyprotein gene, complete cds191111911199%0.099%KU365779.1Select seq gb|KU365780.1|Zika virus strain BeH815744 polyprotein gene, complete cds191021910299%0.099%KU365780.1Select seq gb|KU365777.1|Zika virus strain BeH818995 polyprotein gene, complete cds190931909399%0.099%KU365777.1Select seq gb|KU321639.1|Zika virus strain ZikaSPH2015, complete genome190521905299%0.099%KU321639.1Select seq gb|KJ776791.1|Zika virus strain H/PF/2013 polyprotein gene, complete cds189851898598%0.099%KJ776791.1Select seq gb|KU312312.1|Zika virus isolate Z1106033 polyprotein gene, complete cds185921859296%0.099%KU312312.1Select seq gb|JN860885.1|Zika virus isolate FSS13025 polyprotein gene, partial cds177391773995%0.098%JN860885.1Select seq gb|KF993678.1|Zika virus strain PLCal_ZV from Canada polyprotein gene, partial cds176881768894%0.099%KF993678.1Select seq gb|EU545988.1|Zika virus polyprotein gene, complete cds175851758595%0.098%EU545988.1Select seq gb|HQ234499.1|Zika virus isolate P6-740 polyprotein gene, partial cds164061640695%0.095%HQ234499.1Select seq dbj|LC002520.1|Zika virus genomic RNA, complete genome, strain: MR766-NIID1401514015100%0.089%LC002520.1Select seq gb|KF268949.1|Zika virus isolate ARB15076 polyprotein gene, complete cds1401314013100%0.089%KF268949.1Select seq gb|KF268948.1|Zika virus isolate ARB13565 polyprotein gene, complete cds1400414004100%0.089%KF268948.1Select seq gb|KF268950.1|Zika virus isolate ARB7701 polyprotein gene, complete cds1399713997100%0.089%KF268950.1Select seq gb|AY632535.2|Zika virus strain MR 766, complete genome1394813948100%0.089%AY632535.2Select seq gb|HQ234498.1|Zika virus isolate MR_766 polyprotein gene, partial cds133081330895%0.089%HQ234498.1Select seq gb|KF383115.1|Zika virus strain ArB1362 polyprotein gene, complete cds132971329795%0.089%KF383115.1Select seq gb|KF383119.1|Zika virus strain ArD158084 polyprotein gene, complete cds132861328695%0.089%KF383119.1Select seq gb|KF383116.1|Zika virus strain ArD7117 polyprotein gene, complete cds132481324895%0.089%KF383116.1Select seq gb|DQ859059.1|Zika virus strain MR 766 polyprotein gene, complete cds132481324895%0.089%DQ859059.1Select seq gb|HQ234501.1|Zika virus isolate ArD_41519 polyprotein gene, partial cds132231322395%0.089%HQ234501.1Select seq gb|KF383117.1|Zika virus strain ArD128000 polyprotein gene, complete cds131871318795%0.088%KF383117.1Select seq gb|HQ234500.1|Zika virus isolate IbH_30656 polyprotein gene, partial cds131471314795%0.088%HQ234500.1Select seq gb|KF383118.1|Zika virus strain ArD157995 polyprotein gene, complete cds129721303795%0.088%KF383118.1Select seq gb|KF383121.1|Zika virus strain ArD158095 polyprotein gene, partial cds128821288293%0.089%KF383121.1Select seq gb|KF383120.1|Zika virus strain ArD142623 nonfunctional polyprotein gene, partial sequence108861088693%0.084%KF383120.1Select seq gb|KU312314.1|Zika virus isolate Z1106031 polyprotein gene, partial cds5081508126%0.099%KU312314.1Select seq gb|KU312313.1|Zika virus isolate Z1106032 polyprotein gene, partial cds5056505626%0.099%KU312313.1Select seq gb|KU312315.1|Zika virus isolate Z1106027 polyprotein gene, partial cds3458345817%0.099%KU312315.1Select seq gb|DQ859064.1|Spondweni virus strain SM-6 V-1 polyprotein gene, complete cds2861419391%0.071%DQ859064.1Select seq gb|KJ634273.1|Zika virus strain CK-ISL 2014 E protein (E) gene, partial cds2691269114%0.099%KJ634273.1Select seq gb|KM078936.1|Zika virus strain CHI1410214 NS5 protein gene, partial cds173717379%0.099%KM078936.1Select seq gb|KM078961.1|Zika virus strain CHI2612114 NS5 protein gene, partial cds173617369%0.099%KM078961.1Select seq gb|KM078930.1|Zika virus strain CHI2283714 NS5 protein gene, partial cds173417349%0.099%KM078930.1Select seq gb|KM078971.1|Zika virus strain CHI2613014 NS5 protein gene, partial cds173017309%0.099%KM078971.1Select seq gb|KM078970.1|Zika virus strain CHI2490414 NS5 protein gene, partial cds173017309%0.099%KM078970.1Select seq gb|KM078933.1|Zika virus strain CHI1058514 NS5 protein gene, partial cds173017309%0.099%KM078933.1Select seq gb|KM078929.1|Zika virus strain CHI1805214 NS5 protein gene, partial cds172817289%0.099%KM078929.1Select seq gb|KJ873160.1|Zika virus isolate NC14-03042014-3481 nonstructural protein 5 gene, partial cds158815888%0.099%KJ873160.1Select seq gb|KJ873161.1|Zika virus isolate NC14-02042014-3220 nonstructural protein 5 gene, partial cds140614067%0.099%KJ873161.1Select seq gb|KM851039.1|Zika virus strain SV0127/14 nonstructural protein 5 gene, partial cds137313737%0.099%KM851039.1Select seq gb|KM851038.1|Zika virus strain CPC-0740 nonstructural protein 5 gene, partial cds133713377%0.098%KM851038.1

Sequences producing significant alignments:Select:AllNone Selected:0 AlignmentsDownloadGenBankGraphicsDistance tree of resultsShow/hide columns of the table presenting sequences producing significant alignmentsSequences producing significant alignments:Select for downloading or viewing reportsDescriptionMax scoreTotal scoreQuery coverE valueIdentAccessionSelect seq gb|KU365779.1|Zika virus strain BeH819966 polyprotein gene, complete cds1922819228100%0.0100%KU365779.1Select seq gb|KU365777.1|Zika virus strain BeH818995 polyprotein gene, complete cds1921019210100%0.099%KU365777.1Select seq gb|KU365780.1|Zika virus strain BeH815744 polyprotein gene, complete cds1920119201100%0.099%KU365780.1Select seq gb|KU365778.1|Zika virus strain BeH819015 polyprotein gene, complete cds1911119111100%0.099%KU365778.1Select seq gb|KU321639.1|Zika virus strain ZikaSPH2015, complete genome190861908699%0.099%KU321639.1Select seq gb|KJ776791.1|Zika virus strain H/PF/2013 polyprotein gene, complete cds190211902199%0.099%KJ776791.1Select seq gb|KU312312.1|Zika virus isolate Z1106033 polyprotein gene, complete cds186011860197%0.099%KU312312.1Select seq gb|JN860885.1|Zika virus isolate FSS13025 polyprotein gene, partial cds177661776696%0.098%JN860885.1Select seq gb|KF993678.1|Zika virus strain PLCal_ZV from Canada polyprotein gene, partial cds177211772195%0.099%KF993678.1Select seq gb|EU545988.1|Zika virus polyprotein gene, complete cds176121761296%0.098%EU545988.1Select seq gb|HQ234499.1|Zika virus isolate P6-740 polyprotein gene, partial cds164691646996%0.096%HQ234499.1Select seq dbj|LC002520.1|Zika virus genomic RNA, complete genome, strain: MR766-NIID1393413934100%0.089%LC002520.1Select seq gb|KF268949.1|Zika virus isolate ARB15076 polyprotein gene, complete cds1392813928100%0.089%KF268949.1Select seq gb|KF268948.1|Zika virus isolate ARB13565 polyprotein gene, complete cds1391913919100%0.089%KF268948.1Select seq gb|KF268950.1|Zika virus isolate ARB7701 polyprotein gene, complete cds1391213912100%0.089%KF268950.1Select seq gb|AY632535.2|Zika virus strain MR 766, complete genome1387613876100%0.089%AY632535.2Select seq gb|HQ234498.1|Zika virus isolate MR_766 polyprotein gene, partial cds133391333996%0.089%HQ234498.1Select seq gb|KF383115.1|Zika virus strain ArB1362 polyprotein gene, complete cds133331333396%0.089%KF383115.1Select seq gb|KF383119.1|Zika virus strain ArD158084 polyprotein gene, complete cds133171331796%0.089%KF383119.1Select seq gb|DQ859059.1|Zika virus strain MR 766 polyprotein gene, complete cds132881328896%0.089%DQ859059.1Select seq gb|KF383116.1|Zika virus strain ArD7117 polyprotein gene, complete cds132751327596%0.089%KF383116.1Select seq gb|HQ234501.1|Zika virus isolate ArD_41519 polyprotein gene, partial cds132591325996%0.089%HQ234501.1Select seq gb|KF383117.1|Zika virus strain ArD128000 polyprotein gene, complete cds132091320996%0.088%KF383117.1Select seq gb|HQ234500.1|Zika virus isolate IbH_30656 polyprotein gene, partial cds131891318996%0.088%HQ234500.1Select seq gb|KF383118.1|Zika virus strain ArD157995 polyprotein gene, complete cds130031307196%0.088%KF383118.1Select seq gb|KF383121.1|Zika virus strain ArD158095 polyprotein gene, partial cds129181291893%0.089%KF383121.1Select seq gb|KF383120.1|Zika virus strain ArD142623 nonfunctional polyprotein gene, partial sequence108951089593%0.084%KF383120.1Select seq gb|KU312314.1|Zika virus isolate Z1106031 polyprotein gene, partial cds5081508126%0.099%KU312314.1Select seq gb|KU312313.1|Zika virus isolate Z1106032 polyprotein gene, partial cds5056505626%0.099%KU312313.1Select seq gb|KU312315.1|Zika virus isolate Z1106027 polyprotein gene, partial cds3452345218%0.099%KU312315.1Select seq gb|DQ859064.1|Spondweni virus strain SM-6 V-1 polyprotein gene, complete cds2856419791%0.071%DQ859064.1Select seq gb|KJ634273.1|Zika virus strain CK-ISL 2014 E protein (E) gene, partial cds2686268614%0.099%KJ634273.1Select seq gb|KM078936.1|Zika virus strain CHI1410214 NS5 protein gene, partial cds174617469%0.099%KM078936.1Select seq gb|KM078961.1|Zika virus strain CHI2612114 NS5 protein gene, partial cds174517459%0.099%KM078961.1Select seq gb|KM078930.1|Zika virus strain CHI2283714 NS5 protein gene, partial cds174317439%0.099%KM078930.1Select seq gb|KM078971.1|Zika virus strain CHI2613014 NS5 protein gene, partial cds173917399%0.099%KM078971.1Select seq gb|KM078970.1|Zika virus strain CHI2490414 NS5 protein gene, partial cds173917399%0.099%KM078970.1Select seq gb|KM078933.1|Zika virus strain CHI1058514 NS5 protein gene, partial cds173917399%0.099%KM078933.1Select seq gb|KM078929.1|Zika virus strain CHI1805214 NS5 protein gene, partial cds173717379%0.099%KM078929.1Select seq gb|KJ873160.1|Zika virus isolate NC14-03042014-3481 nonstructural protein 5 gene, partial cds159715978%0.099%KJ873160.1Select seq gb|KJ873161.1|Zika virus isolate NC14-02042014-3220 nonstructural protein 5 gene, partial cds141514157%0.099%KJ873161.1Select seq gb|KM851039.1|Zika virus strain SV0127/14 nonstructural protein 5 gene, partial cds138213827%0.099%KM851039.1Select seq gb|KM851038.1|Zika virus strain CPC-0740 nonstructural protein 5 gene, partial cds134613467%0.098%KM851038.1

Sequences producing significant alignments:Select:AllNone Selected:0 AlignmentsDownloadGenBankGraphicsDistance tree of resultsShow/hide columns of the table presenting sequences producing significant alignmentsSequences producing significant alignments:Select for downloading or viewing reportsDescriptionMax scoreTotal scoreQuery coverE valueIdentAccessionSelect seq gb|KU365780.1|Zika virus strain BeH815744 polyprotein gene, complete cds1922819228100%0.0100%KU365780.1Select seq gb|KU365777.1|Zika virus strain BeH818995 polyprotein gene, complete cds1921919219100%0.099%KU365777.1Select seq gb|KU365779.1|Zika virus strain BeH819966 polyprotein gene, complete cds1920119201100%0.099%KU365779.1Select seq gb|KU365778.1|Zika virus strain BeH819015 polyprotein gene, complete cds1910219102100%0.099%KU365778.1Select seq gb|KU321639.1|Zika virus strain ZikaSPH2015, complete genome190771907799%0.099%KU321639.1Select seq gb|KJ776791.1|Zika virus strain H/PF/2013 polyprotein gene, complete cds190121901299%0.099%KJ776791.1Select seq gb|KU312312.1|Zika virus isolate Z1106033 polyprotein gene, complete cds185921859297%0.099%KU312312.1Select seq gb|JN860885.1|Zika virus isolate FSS13025 polyprotein gene, partial cds177621776296%0.098%JN860885.1Select seq gb|KF993678.1|Zika virus strain PLCal_ZV from Canada polyprotein gene, partial cds177061770695%0.099%KF993678.1Select seq gb|EU545988.1|Zika virus polyprotein gene, complete cds175981759896%0.098%EU545988.1Select seq gb|HQ234499.1|Zika virus isolate P6-740 polyprotein gene, partial cds164691646996%0.096%HQ234499.1Select seq dbj|LC002520.1|Zika virus genomic RNA, complete genome, strain: MR766-NIID1393413934100%0.089%LC002520.1Select seq gb|KF268949.1|Zika virus isolate ARB15076 polyprotein gene, complete cds1392313923100%0.089%KF268949.1Select seq gb|KF268948.1|Zika virus isolate ARB13565 polyprotein gene, complete cds1392313923100%0.089%KF268948.1Select seq gb|KF268950.1|Zika virus isolate ARB7701 polyprotein gene, complete cds1391613916100%0.089%KF268950.1Select seq gb|AY632535.2|Zika virus strain MR 766, complete genome1387613876100%0.089%AY632535.2Select seq gb|HQ234498.1|Zika virus isolate MR_766 polyprotein gene, partial cds133351333596%0.089%HQ234498.1Select seq gb|KF383115.1|Zika virus strain ArB1362 polyprotein gene, complete cds133331333396%0.089%KF383115.1Select seq gb|KF383119.1|Zika virus strain ArD158084 polyprotein gene, complete cds133131331396%0.089%KF383119.1Select seq gb|DQ859059.1|Zika virus strain MR 766 polyprotein gene, complete cds132881328896%0.089%DQ859059.1Select seq gb|KF383116.1|Zika virus strain ArD7117 polyprotein gene, complete cds132751327596%0.089%KF383116.1Select seq gb|HQ234501.1|Zika virus isolate ArD_41519 polyprotein gene, partial cds132681326896%0.089%HQ234501.1Select seq gb|KF383117.1|Zika virus strain ArD128000 polyprotein gene, complete cds132051320596%0.088%KF383117.1Select seq gb|HQ234500.1|Zika virus isolate IbH_30656 polyprotein gene, partial cds131891318996%0.088%HQ234500.1Select seq gb|KF383118.1|Zika virus strain ArD157995 polyprotein gene, complete cds129991306796%0.088%KF383118.1Select seq gb|KF383121.1|Zika virus strain ArD158095 polyprotein gene, partial cds129091290993%0.089%KF383121.1Select seq gb|KF383120.1|Zika virus strain ArD142623 nonfunctional polyprotein gene, partial sequence108861088693%0.084%KF383120.1Select seq gb|KU312314.1|Zika virus isolate Z1106031 polyprotein gene, partial cds5077507726%0.099%KU312314.1Select seq gb|KU312313.1|Zika virus isolate Z1106032 polyprotein gene, partial cds5052505226%0.099%KU312313.1Select seq gb|KU312315.1|Zika virus isolate Z1106027 polyprotein gene, partial cds3452345218%0.099%KU312315.1Select seq gb|DQ859064.1|Spondweni virus strain SM-6 V-1 polyprotein gene, complete cds2861419791%0.071%DQ859064.1Select seq gb|KJ634273.1|Zika virus strain CK-ISL 2014 E protein (E) gene, partial cds2686268614%0.099%KJ634273.1Select seq gb|KM078936.1|Zika virus strain CHI1410214 NS5 protein gene, partial cds174617469%0.099%KM078936.1Select seq gb|KM078961.1|Zika virus strain CHI2612114 NS5 protein gene, partial cds174517459%0.099%KM078961.1Select seq gb|KM078930.1|Zika virus strain CHI2283714 NS5 protein gene, partial cds174317439%0.099%KM078930.1Select seq gb|KM078971.1|Zika virus strain CHI2613014 NS5 protein gene, partial cds173917399%0.099%KM078971.1Select seq gb|KM078970.1|Zika virus strain CHI2490414 NS5 protein gene, partial cds173917399%0.099%KM078970.1Select seq gb|KM078933.1|Zika virus strain CHI1058514 NS5 protein gene, partial cds173917399%0.099%KM078933.1Select seq gb|KM078929.1|Zika virus strain CHI1805214 NS5 protein gene, partial cds173717379%0.099%KM078929.1Select seq gb|KJ873160.1|Zika virus isolate NC14-03042014-3481 nonstructural protein 5 gene, partial cds159715978%0.099%KJ873160.1Select seq gb|KJ873161.1|Zika virus isolate NC14-02042014-3220 nonstructural protein 5 gene, partial cds141514157%0.099%KJ873161.1Select seq gb|KM851039.1|Zika virus strain SV0127/14 nonstructural protein 5 gene, partial cds138213827%0.099%KM851039.1Select seq gb|KM851038.1|Zika virus strain CPC-0740 nonstructural protein 5 gene, partial cds134613467%0.098%KM851038.1

Sequences producing significant alignments:Select:AllNone Selected:0 AlignmentsDownloadGenBankGraphicsDistance tree of resultsShow/hide columns of the table presenting sequences producing significant alignmentsSequences producing significant alignments:Select for downloading or viewing reportsDescriptionMax scoreTotal scoreQuery coverE valueIdentAccessionSelect seq gb|KU365777.1|Zika virus strain BeH818995 polyprotein gene, complete cds1922819228100%0.0100%KU365777.1Select seq gb|KU365780.1|Zika virus strain BeH815744 polyprotein gene, complete cds1921919219100%0.099%KU365780.1Select seq gb|KU365779.1|Zika virus strain BeH819966 polyprotein gene, complete cds1921019210100%0.099%KU365779.1Select seq gb|KU365778.1|Zika virus strain BeH819015 polyprotein gene, complete cds1909319093100%0.099%KU365778.1Select seq gb|KU321639.1|Zika virus strain ZikaSPH2015, complete genome190681906899%0.099%KU321639.1Select seq gb|KJ776791.1|Zika virus strain H/PF/2013 polyprotein gene, complete cds190031900399%0.099%KJ776791.1Select seq gb|KU312312.1|Zika virus isolate Z1106033 polyprotein gene, complete cds185831858397%0.099%KU312312.1Select seq gb|JN860885.1|Zika virus isolate FSS13025 polyprotein gene, partial cds177571775796%0.098%JN860885.1Select seq gb|KF993678.1|Zika virus strain PLCal_ZV from Canada polyprotein gene, partial cds177031770395%0.099%KF993678.1Select seq gb|EU545988.1|Zika virus polyprotein gene, complete cds175941759496%0.098%EU545988.1

The bloody truth about Zika virusPOSTED 5:28 PM, FEBRUARY 3, 2016, BY MBODDEKERFACEBOOKTWITTERGOOGLEPINTERESTLINKEDINEMAIL HOUSTON - Listen up! Mosquito pricks are not the only ones you have to worry about giving you the Zika virus. “We have one documented case, and now maybe a second one in Dallas of sexual transmission but that’s very, very rare, but if there’s an exchange of blood or bodily fluids there is that potential for a spread,” says Dr. Catherine Troisi of the UT Health School of Public Health . This “bloody” truth has the folks at the Blood Center on alert. Susan Rossmann, Chief Medical Officer at the Gulf Coast Regional Blood Center, says, “We are asking people who have been to the areas affected by Zika which is all of Mexico, the Caribbean, Central and South America to not donate blood for 28 days after they come back. That’s because people may have Zika and not know it.” She`s right. Most people don`t have any symptoms, and only about one in five even knows they`re sick. And, the Zika virus is spreading very quickly. “Because the virus hasn’t been around in this part of the world, nobody has any immunity, so everybody is susceptible,” says Dr. Troisi. At Bush Intercontinental Airport, we checked in with vacationers coming home from Latin America to see if they're worried. “No we’re not. We didn’t even see a mosquito when we were there," says Jim Crebbin. One woman told us, “I’m not at all worried." But her friend was saying something else, “To some degree. I’ve got younger kids who are eventually going to get pregnant.” We also ran into one young woman who has a friend in El Salvador that has the Zika virus. She told us, “She went to the doctor, she had a rash, and they tested her and it was Zika. The doctor told her not to have children for two years because it would directly affect the fetus.” That's serious. On the upside, experts believe once the Zika virus clears the body, the patient will be immune to it for the rest of their life. The Zika virus is more proof that the only good mosquito is a dead one.