Human and Poultry HPAI H7N9 In Guangdong China

[niman]

In January 2017, Guangdong Provincial Center for Disease Control and Disease on the two cases of human infection H7N9 cases were isolated virus gene sequencing analysis, found in the two strains of hemagglutinin link peptide position of the gene insertion mutation occurred, the test results Has been confirmed by the National Center for Viral Disease National Influenza Center.

I center experts to judge and communicate with the relevant experts in the agricultural sector that H7N9 virus in the hemagglutinin link peptide position of the gene insertion mutation, suggesting that the virus mutation to the highly pathogenic virus against birds;

http://www.cdcp.org.cn/gdsjbyfkzzx/gnwxx001/201702/ce3a2125d5dc46e1b2e906ee42d42c2d.shtml

 

[niman]

H7N9 virus mutant was found in human cases from China

 

Release Date: 2017-02-19

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In January 2017, Guangdong Provincial Center for Disease Control and Disease on the two cases of human infection H7N9 cases were isolated virus gene sequencing analysis, found in the two strains of hemagglutinin link peptide position of the gene insertion mutation occurred, the test results Has been confirmed by the National Center for Viral Disease National Influenza Center.

I center experts to judge and communicate with the relevant experts in the agricultural sector that H7N9 virus in the hemagglutinin link peptide position of the gene insertion mutation, suggesting that the virus mutation to the highly pathogenic virus against birds; the second is based on the virus Sequence analysis results have not yet appeared in the mutant virus that has increased resistance to human infectivity, virulence and interpersonal communication.

Two cases of disease before the incidence of bird exposure history, and in the exposure of poultry birds have occurred in the phenomenon of death. At present, a case has been cured, another case is still in treatment. All the 105 cases of close contact after two weeks of medical observation, were not fever, cough and other symptoms.

H7N9 virus is a influenza virus, one of its main features is prone to gene reassignment and mutation. Some mutations may lead to the virus on the human appeal, virulence and interpersonal communication ability enhancement, so the virus variation has been widely concerned about the domestic and foreign.

It is understood that the agricultural sector laboratory also from Guangdong, four poultry specimens found similar to the variation of the virus. China's health care system will work together with the agricultural sector, the common source of the virus, the scope of the impact of in-depth study, and continue to strengthen the monitoring of H7N9 virus, in time to find any possible variation.

The results have been communicated to the World Health Organization.

China Center for Disease Control and Prevention

[niman]

Mainland H7N9 transmission virus found variants

Posted: 2017/02/19 19:12

Latest update: 2017/02/19 19:12

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(Guangdong Provincial Center for Disease Control and Prevention) informed that in 2 cases of H7N9 infection, found that the virus, which means that the virus has been mutated into a highly pathogenic virus for poultry. Mainland China has informed the World Health Organization. 

China recently H7N9 avian influenza epidemic extended, February 6 to 12 the whole continent informed 69 cases of H7N9 cases, of which 8 were killed. Most of the H7N9 cases in mainland China occur in the Yangtze River Delta and the Pearl River Delta region. Exposure to infected birds or exposure to live poultry markets is an important risk factor for human infection. 

Guangdong Provincial Center for Disease Control and Prevention today reported that in January this year, the center of 2 cases of H7N9 human infection cases for further genetic sequencing analysis found that the two strains of hemagglutinin link peptide gene insertion mutation, which means that the virus Mutations into birds with highly pathogenic viruses. 

In the new network quoted the Guangdong Provincial Center for Disease Control and Prevention experts and experts in the agricultural sector to communicate after the investigation that the variability of the virus analysis of the results of the human infection has not yet found, the proliferation of human and human transmission of enhanced mutations. 

It is understood that these two cases before the disease have been exposed to the poultry environment. At present a case has been recovered, another case is still in the treatment. 105 had close contact with the patient, after 2 weeks of observation, did not appear signs of infection. 

In addition to virus variants found in human-infected strains, the Chinese mainland's agricultural sector laboratory also found similar variants of virus in four poultry specimens from Guangdong, and the Chinese community's health care system will conduct in-depth research with the agricultural sector on variants , And continue to strengthen the monitoring of H7N9 virus. 

The report said that the Chinese authorities have informed the results of the WHO (WHO).1060219

 

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Edited February 19, 2017 by niman