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nCoV orf 8 Mutation Found In WA, IL, CA, AZ and Shenzhen Cluster


niman

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Full sequences for all five confirmed cases in the United States have been released and all except for Orange Co in California have the orf 8 mutation present in Shenzhen cluster described in Lancet.  The orf 8 gene acquired in 29 nt deletion and was present in the physician at the Metropole Hotel who was the index case for the international expansion of SARS in 2003.

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  • niman changed the title to nCoV orf 8 Mutation Found In WA, IL, CA, AZ and Shenzhen Cluster
Virus detail
Virus name: BetaCoV/USA/AZ1/2020
Accession ID: EPI_ISL_406223
Type: betacoronavirus
Passage details/history: Original
Sample information
Collection date: 2020-01-22
Location: USA / Arizona / Phoenix
Host: Human
Additional location information:  
   
   
Edited by niman
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Virus detail
Virus name: BetaCoV/USA/CA1/2020
Accession ID: EPI_ISL_406034
Type: betacoronavirus
Passage details/history: Original
Sample information
Collection date: 2020-01-23
Location: USA / California / Los Angeles
Host: Human
   
   
   
Edited by niman
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Virus detail
Virus name: BetaCoV/USA/IL1/2020
Accession ID: EPI_ISL_404253
Type: unclassified betacoronavirus
Passage details/history: Original
Sample information
Collection date: 2020-01-21
Location: USA / Illinois /Chicago
Host: Human
Additional location information:  
   
   
   
Edited by niman
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Note: 5' end is primer sequence used
Virus detail
Virus name: BetaCoV/USA/WA1/2020
Accession ID: EPI_ISL_404895
Type: betacoronavirus
Passage details/history: Original
Sample information
Collection date: 2020-01-19
Location: USA / Washington / Snohomish County
Host: Human
Additional location information:  
   
   
   
   
   
Edited by niman
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s detail
Virus name: BetaCoV/Shenzhen/HKU-SZ-002/2020
Accession ID: EPI_ISL_406030
Type: betacoronavirus
Passage details/history: Original
Sample information
Collection date: 2020-01
Location: China / Guangdong / Shenzhen
Host: Human
Additional location information:  
   
   
   
   
   
   
   
   
   
   
   
 
   
   
   
   
   
   
   
 
   
   
   
 
Edited by niman
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Virus detail
Virus name: BetaCoV/Shenzhen/HKU-SZ-005/2020
Accession ID: EPI_ISL_405839
Type: betacoronavirus
Passage details/history: Original
Sample information
Collection date: 2020-01
Location: China / Guangdong / Shenzhen
Host: Human
Additional location information:  
   
   
   
   
   
   
   
   
   
   
   
Institute information
Originating lab: The University of Hong Kong - Shenzhen Hospital
Address: 1 Haiyuan 1st Road, Futian District, Shenzhen 518053, Guangdong, China
Sample ID given by the sample provider: HKU-SZ-005_2020
Submitting lab: Li Ka Shing Faculty of Medicine, The University of Hong Kong
Address: 21 Sassoon Road, Pokfulam, Hong Kong, Hong Kong (SAR)
Sample ID given by the submitting laboratory:  
Authors: Chan,J.F.-W., Yuan,S., Kok,K.H., To,K.K.-W., Chu,H., Yang,J., Xing,F., Liu,J., Yip,C.C.-Y., Poon,R.W.-S., Tsai,H.W., Lo,S.K.-F., Chan,K.H., Poon,V.K.-M., Chan,W.M., Ip,J.D., Cai,J.P., Cheng,V.C.-C., Chen,H., Hui,C.K.-M. and Yuen,K.Y.
Submitter information
Submitter: Jasper Fuk Woo Chan
Submission Date: 2020-01-24
Address: Li Ka Shing Faculty of Medicine, The University of Hong Kong
21 Sassoon Road, Pokfulam, Hong Kong, Hong Kong (SAR)
FASTA
>BetaCoV/Shenzhen/HKU-SZ-005/2020|EPI_ISL_405839
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il
Virus name: BetaCoV/Guangdong/20SF013/2020
Accession ID: EPI_ISL_403933
Type: betacoronavirus
Passage details/history: Original
Sample information
Collection date: 2020-01-15
Location: Guangdong, China
Host: Human
Additional location information: Shenzhen City
   
   
Edited by niman
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Virus detail
Virus name: BetaCoV/Guangdong/20SF014/2020
Accession ID: EPI_ISL_403934
Type: betacoronavirus
Passage details/history: Original
Sample information
Collection date: 2020-01-15
Location: Guangdong, China
Host: Human
Additional location information: Shenzhen City
   
   
   
Edited by niman
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Virus detail
Virus name: BetaCoV/Guangdong/20SF025/2020
Accession ID: EPI_ISL_403935
Type: betacoronavirus
Passage details/history: Original
Sample information
Collection date: 2020-01-15
Location: Guangdong, China
Host: Human
Additional location information: Shenzhen City
   
   
Edited by niman
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Pneumonia situation of new coronavirus infection in Guangdong Province at 12:00 on January 28, 2020

Time: 2020-01-28 18:22:51 source: this website

 

  As of 12:00 on January 28, the province has reported a total of 207 confirmed cases of pneumonia due to new coronavirus infection. At 02:00 on the 28th, there were 19 new confirmed cases in the province, of which 1 case was reported for the first time in Heyuan City, 8 cases were in Shenzhen, 5 cases were in Dongguan, 2 cases were in Zhanjiang, 1 case was in Yangjiang, and 1 was in Meizhou Case, 1 case in Qingyuan City. 1,027 close contacts are under medical observation.

  Among the 207 cases diagnosed in our province, 102 were male and 105 were female, aged between 11 months and 85 years. There were 57 cases in Shenzhen, 51 cases in Guangzhou, 18 cases in Foshan, 12 cases in Zhuhai, 11 cases in Huizhou, 9 cases in Yangjiang, 7 cases in Zhanjiang, 7 cases in Dongguan, 6 cases in Zhongshan, 6 cases in Qingyuan, There were 5 cases in Shantou, 4 in Zhaoqing, 4 in Shaoguan, 4 in Jieyang, 4 in Meizhou, 1 in Shanwei, and 1 in Heyuan. At present, there are 6 critical cases, 20 severe cases, and no deaths.

http://wsjkw.gd.gov.cn/zwyw_yqxx/content/post_2879855.html

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 A rather unexpected finding from the lung CT scan of patient 5, which was done on the insistence by the nervous parents, also showed ground-glass pneumonic changes. Patient 5 was later confirmed virologically to have an asymptomatic infection. Although asymptomatic patients with SARS were uncommon, they were documented in our retrospective study in the minor 2004 SARS outbreak after reopening of the wildlife market in Guangzhou.

 Notably, patients 3 and 4 were afebrile at presentation to our hospital. These cryptic cases of walking pneumonia might serve as a possible source to propagate the outbreak. Further studies on the epidemiological significance of these asymptomatic cases are warranted.

https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(20)30154-9/fulltext

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Hosted by: 
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Produced by: 
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Program:: 
Presswatch
Air date: 
Thu, 01/30/2020 - 9:00am to 9:30am
virus
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Henry Niman, Ph.D.
Wuhan Coronavirus: how dangerous is it?
As we go to press the Wuhan Novel Coronavirus has infected thousands and slipped the bonds of massive quarantines in China.  How dangerous is it, how is it likely to spread, and what can you do about it (if anything)?  Join me as I welcome Dr. Henry Niman, Ph.D., internationally consulted virus researcher, as heard on KBOO in 2009 about the Swine Flu pandemic, and during 2014 during the Ebola outbreak.  

KBOO brings you the news you're not supposed to know, the analysis borne of decades of inquiry into our corporate-biased press. 

https://kboo.fm/media/78400-presswatch-possible-pandemic

 

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