Zika Virus

With “well over 500” cases of the Zika virus currently in the U.S., Dr. Anthony Fauci, director of the National Institute of Allergy andInfectious Diseases, said on “This Week” Sunday that “forceful preparation” will be critical to preventing further spread in the U.S. this summer. “We already have Zika in the United States. But it is travel related,” Dr. Fauci said on ABC’s “This Week.” “The concern is that we will have local transmission; in other words, people who get infected in the United States, get bitten by a mosquito, but who have never left the continental United States. We fully expect that that will happen as we get to the more robust mosquito season in the ne…

CDC presser cites 279 Zika linked pregnancies in US and territories.

CDC Telebriefing: Zika Virus Update WHAT: CDC will host a telebriefing to provide an update on the Zika Virus WHO: Denise J. Jamieson, MD, MPH, CAPT, USPHS, Co-Lead, Pregnancy and Birth Defects Team, CDC Zika Virus Response Team Margaret Honein, MD, Chief, Birth Defects Branch, National Center for Birth Defects and Developmental Disabilities WHEN: Friday, May 20, 2016, at 10:00 am EDT DIAL-IN: Media: 888-790-3525 Non-Media: 888-917-8054 International: 1-630-395-0068 Passcode: CDC Media

Possible Zika Virus Infection Among Pregnant Women — United States and Territories, May 2016Early Release / May 20, 2016 / 65 http://www.cdc.gov/mmwr/volumes/65/wr/mm6520e1.htm?s_cid=mm6520e1_w

Zika situation report19 May 2016Zika virus, Microcephaly and Guillain-Barré syndromehttp://www.who.int/emergencies/zika-virus/situation-report/19-may-2016/en/

This Media Advisory is being forwarded on behalf of the WHO Regional Office for Europe:> > > MEDIA ADVISORY: Virtual press briefing on WHO assessment of the risk of Zika virus spread in the European Region> > On Wednesday 18 May, WHO will publish its first assessment of the risk of Zika virus spread in the European Region in late spring and summer. The report assesses the risk of a Zika virus outbreak based on the combination of two factors: the likelihood of Zika virus spread and existing national capacity to prevent and/or rapidly contain local transmission. It provides a breakdown of which countries have high, moderate, low, very low or no likelihood of …

Pregnancy management in the context of Zika virus infectionInterim guidance updateShare PrintAuthors: World Health Organization Publication detailsNumber of pages: 14 Publication date: Updated 13 May 2016 (Originally published 2 March 2016) Languages: English WHO reference number:WHO/ZIKV/MOC/16.2 Rev.1 DownloadsPregnancy management in the context of Zika virushttp://www.who.int/csr/resources/publications/zika/pregnancy-management/en/

Zika virus and the 2016 Rio Olympic and Paralympic GamesWHO statement 12 May 2016 http://www.who.int/mediacentre/news/statements/2016/zika-olympics/en/

Zika situation report12 May 2016Zika virus, Microcephaly and Guillain-Barré syndromeRead the full situation reporthttp://who.int/emergencies/zika-virus/situation-report/12-may-2016/en/

Zika Virus Infection during Pregnancy in Mice Causes Placental Damage and Fetal DemiseJonathan J. Miner8, Bin Cao8, Jennifer Govero8, Amber M. Smith, Estefania Fernandez, Omar H. Cabrera, Charise Garber,Michelle Noll, Robyn S. Klein, Kevin K. Noguchi, Indira U. Mysorekar, Michael S. Diamond8Co-first authorsPublication stage: In Press Corrected Proof DOI: http://dx.doi.org/10.1016/j.cell.2016.05.008 Article Infohttp://www.cell.com/cell/fulltext/S0092-8674(16)30556-6

Zika Virus Disrupts Neural Progenitor Development and Leads to Microcephaly in Mice http://www.cell.com/cell-stem-cell/pdfExtended/S1934-5909(16)30084-4

Press Contacts> > > May 10, 2016> > Up Comparison of Zika virus testing in serum, urine and saliva specimens from travel-associated Zika virus disease cases–Florida, 2016> > CDC Media Relations> 404-639-3286> > Interim guidance for Zika virus testing on urine ― United States, 2016> > CDC Media Relations> 404-639-3286> > Reduced Prevalence of Chikungunya Virus Infection in Communities with Ongoing Aedes Aegypti Mosquito Trap Intervention Studies – Salinas and Guayama, Puerto Rico, November 2015–February 2016> > CDC Media Relations> 404-639-3286> > > > The MMWR is embargoed until 1:00 PM ET May 10, 2016> &…

Brief ReportSwitch to Standard View Wolbachia Blocks Currently Circulating Zika Virus Isolates in BrazilianAedes aegypti MosquitoesHeverton Leandro Carneiro Dutra, Marcele Neves Rocha, Fernando Braga Stehling Dias, Simone Brutman Mansur,Eric Pearce Caragata, Luciano Andrade MoreiraPublication stage: In Press Corrected ProofOpen AccessDOI: http://dx.doi.org/10.1016/j.chom.2016.04.021 Open access funded by Bill & Melinda Gates Foundation http://www.cell.com/cell-host-microbe/fulltext/S1931-3128(16)30157-3

Zika situation report28 April 2016Zika virus, Microcephaly and Guillain-Barré syndromeRead the full situation report Summary:As of 27 April, 55 countries and territories report continuing mosquito-borne transmission; for 42 countries this is their first documented Zika virus outbreak (Fig. 1). Mosquito-borne transmission (Table 1): 42 countries are experiencing a first outbreak of Zika virus since 2015, with no previous evidence of circulation, and with ongoing transmission by mosquitos.13 countries reported evidence of Zika virus transmission between 2007 and 2014, with ongoing transmission.Four countries or territories have reported an outbreak since 2015 that is now …

At least half of 40 brain scans from Brazil that Dr. William Dobyns has examined meet criteria for a rare condition known as fetal brain disruption sequence, a previously rare and highly destructive condition, according to the Seattle Children’s hospital medical geneticist and pediatric neurologist. “The brain in a fetus is growing and growing and growing,” he explained. “Then something really bad happens. The brain shrinks and the skull collapses.”It’s a condition much more severe than the microcephaly linked to Zika early on, a disorder in which babies are born with smaller-than-normal heads, Dobyns said. The growing cases are more evidence that the largely mosquito-bor…

Brain-Region-Specific Organoids Using Mini-bioreactors for Modeling ZIKV ExposureXuyu Qian18, Ha Nam Nguyen18, Mingxi M. Song, Christopher Hadiono, Sarah C. Ogden, Christy Hammack, Bing Yao,Gregory R. Hamersky, Fadi Jacob, Chun Zhong, Ki-jun Yoon, William Jeang, Li Lin, Yujing Li, Jai Thakor, Daniel A. Berg, Ce Zhang,Eunchai Kang, Michael Chickering, David Nauen, Cheng-Ying Ho, Zhexing Wen, Kimberly M. Christian, Pei-Yong Shi, Brady J. Maher, Hao Wu, Peng Jin, Hengli Tang, Hongjun Song, Guo-li Ming18Co-first authorsPublication stage: In Press Corrected Proof DOI: http://dx.doi.org/10.1016/j.cell.2016.04.032 http://www.cell.com/cell/abstract/S0092-8674(16)30467-6 Article I…

Zika situation report21 April 2016http://www.who.int/emergencies/zika-virus/situation-report/21-april-2016/en/ Zika virus, Microcephaly and Guillain-Barré syndrome Read the full situation report Click to enlarge image

Zika Virus and Birth Defects — Reviewing the Evidence for CausalitySonja A. Rasmussen, M.D., Denise J. Jamieson, M.D., M.P.H., Margaret A. Honein, Ph.D., M.P.H., and Lyle R. Petersen, M.D., M.P.H. April 13, 2016DOI: 10.1056/NEJMsr1604338 http://www.nejm.org/doi/full/10.1056/NEJMsr1604338?query=featured_home

Zika virus impairs growth in human neurospheres and brain organoidsPatricia P. Garcez1,2,*, Erick Correia Loiola2,†, Rodrigo Madeiro da Costa2,†,Luiza M. Higa3,†, Pablo Trindade2,†, Rodrigo Delvecchio3, Juliana Minardi Nascimento2,4, Rodrigo Brindeiro3, Amilcar Tanuri3, Stevens K. Rehen2,1,*+ Author Affiliations ↵*Corresponding author. Email: [email protected] (P.P.G.); [email protected](S.K.R.)↵† These authors contributed equally to this work. Science 10 Apr 2016:DOI: 10.1126/science.aaf6116 http://science.sciencemag.org/content/early/2016/04/08/science.aaf6116.full

Zika virus impairs growth in human neurospheres and brain organoidshttps://peerj.com/preprints/1817/ Cell BiologyDevelopmental BiologyNeuroscience

Zika situation report7 April 2016Zika virus, Microcephaly and Guillain-Barré syndromehttp://www.who.int/emergencies/zika-virus/situation-report/7-april-2016/en/

Brief ReportSwitch to Standard View Expression Analysis Highlights AXL as a Candidate Zika Virus Entry Receptor in Neural Stem Cellshttp://www.cell.com/cell-stem-cell/fulltext/S1934-5909(16)00118-1

Characterization of a Novel Murine Model to Study Zika Virushttp://www.ajtmh.org/content/early/2016/03/24/ajtmh.16-0111.full.pdf+html