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USA/IL-Yale-S115/2021 1/7 matched B.1.1.7 with 3 AAs deleted in Spike protein, 3 AAs deleted in NSP6 and Q27 stop codon in NS8. map update https://www.google.com/maps/d/u/1/edit?mid=1aQDSL2LwQFbuoCAg_nIOPK8D-LIJ5MYd&ll=41.85430829242347%2C-88.53460407693667&z=8

USA/IL-Yale-S121/2021 1/8 matched B.1.1.7 with 3 AAs deleted in Spike protein, 3 AAs deleted in NSP6 and Q27 stop codon in NS8. map update https://www.google.com/maps/d/u/1/edit?mid=1aQDSL2LwQFbuoCAg_nIOPK8D-LIJ5MYd&ll=41.85430829242347%2C-88.53460407693667&z=8

USA/IL-Yale-S140/2021 1/14 matched B.1.1.7 with 3 AAs deleted in Spike protein, 3 AAs deleted in NSP6 and Q27 stop codon in NS8. map update https://www.google.com/maps/d/u/1/edit?mid=1aQDSL2LwQFbuoCAg_nIOPK8D-LIJ5MYd&ll=41.85430829242347%2C-88.53460407693667&z=8

Grubaugh Lab has released eight B.1.1.7 SARS CoV2 sequences collected Jan 6-15. USA/IL-Yale-S140/2021 1/14 USA/IL-Yale-S121/2021 1/8 USA/IL-Yale-S115/2021 1/7 USA/IL-Yale-S147/2021 1/5 USA/IL-Yale-S120/2021 1/8 USA/IL-Yale-S116/2021 1/7 USA/IL-Yale-S112/2021 1/6 USA/IL-Yale-S146/2021 1/15

USA/NY-Yale-S107/2021 1/8 matched B.1.1.7 with 3 AAs deleted in Spike protein, 3 AAs deleted in NSP6 and Q27 stop codon in NS8. map update https://www.google.com/maps/d/u/1/edit?mid=1aQDSL2LwQFbuoCAg_nIOPK8D-LIJ5MYd&ll=41.028629735047645%2C-73.84837195924958&z=11

Grubaugh Lab has released a B.1.1.7 SARS CoV2 sequence (USA/NY-Yale-S107/2021) collected Jan 8 in Westchester Co.

USA/NJ-Yale-S133/2021 1/9 matched B.1.1.7 with 3 AAs deleted in Spike protein, 3 AAs deleted in NSP6 and Q27 stop codon in NS8. map update https://www.google.com/maps/d/u/1/edit?mid=1aQDSL2LwQFbuoCAg_nIOPK8D-LIJ5MYd&ll=40.817566791332965%2C-74.25260287214272&z=10

Grubaugh Lab has released six B.1.1.7 SARS CoV2 sequences collected Jan 6-14. USA/NJ-Yale-S133/2021 1/9 USA/NJ-Yale-S143/2021 1/14 USA/NJ-Yale-S142/2021 1/14 USA/NJ-Yale-S114/2021 1/6 USA/NJ-Yale-S141/2021 1/14 USA/NJ-Yale-S132/2021 1/9

USA/WA-UW-55545/2021 1/16 matched B.1.1.7 with 3 AAs deleted in Spike protein, 3 AAs deleted in NSP6 and Q27 stop codon in NS8. map update https://www.google.com/maps/d/u/1/edit?mid=1aQDSL2LwQFbuoCAg_nIOPK8D-LIJ5MYd&ll=47.61285770602534%2C-122.42400459804688&z=11

USA/WA-UW-55538/2021 1/16 matched B.1.1.7 with 3 AAs deleted in Spike protein, 3 AAs deleted in NSP6 and Q27 stop codon in NS8. map update https://www.google.com/maps/d/u/1/edit?mid=1aQDSL2LwQFbuoCAg_nIOPK8D-LIJ5MYd&ll=47.61285770602534%2C-122.42400459804688&z=11

UW Virology Lab has released two B.1.1.7 SARS CoV2 sequences (USA/WA-UW-55538/2021, USA/WA-UW-55545/2021) collected Jan 16.

USA/OR-CDC-STM-UNK1166/2021 Yamhill County Oregon map update https://www.google.com/maps/d/u/1/edit?mid=1aQDSL2LwQFbuoCAg_nIOPK8D-LIJ5MYd&ll=45.121304721481586%2C-123.35297661646675&z=10

The sequence for the Yamhill case has not been released. It will be assigned a UNK number, which will be updated upon release. USA/OR-CDC-STM-UNK166/2021 Yamhill County Oregon Oregon Health Authority learned of the discovery on Friday. The case is a Yamhill County resident with no known travel history. Health officials are working to determine the source of the infection.

Posted on: January 23, 2021 COVID-19 Variant in Washtenaw County: Testing Encouraged (1/23 Update) Cases of the COVID-19 variant B117 have been identified in Washtenaw County. A total of 5 cases of the variant have been identified and additional sequencing continues for other possible cases already positive for COVID-19. Washtenaw County Health Department is now aware of a possible public exposure. Brief, public exposures are not normally a COVID-19 exposure concern but the B117 variant is more easily transmitted and could lead to more cases, hospitalizations, and deaths. As a precaution, the Health Department recommends immediate COVID-19 testing for anyone in the following locations at the specific times provided: Sun, Jan 17 at the Meijer on Ann Arbor Saline Rd., Ann Arbor MI from 9:00 to 10:00 am Sun, Jan 17 Briarwood Mall, 100 Briarwood Circle, Ann Arbor MI from 1:00 to 2:00 pm Everyone should be aware of this new variant and limit any possible exposures to COVID-19. This includes not gathering with people outside of your household and limiting more risky behaviors where social distancing and wearing masks cannot be consistently done. Anyone who has symptoms of COVID-19, has been recently exposed, or who has recently traveled to a place where a new variant is circulating should be tested. “The possibility of additional spread of the variant is a concern,” says Juan Luis Marquez, MD, MPH, medical director with Washtenaw County Health Department. “At this point and with the guidance of the Michigan Department of Health and Human Services, we are encouraging extra precautions. Seek testing if you have symptoms, have recently been exposed to COVID-19, or have recently traveled to a place where the new variant is circulating. And everyone should make sure they are using all COVID-19 precautions consistently. This includes face masks, social distancing, hand cleaning, avoiding crowds or gatherings, and following isolation and quarantine guidance.” The initial case of the B117 variant was identified on Jan 16 in the University of Michigan community. It is not clear if all subsequent cases are connected to this first case. Washtenaw County Health Department, MDHHS and the university are working closely to implement additional containment strategies to slow the spread of the variant. “We have been warning people for weeks that this variant would likely be identified in the State of Michigan,” says Dr Joneigh Khaldun, chief medical executive and chief deputy for health at MDHHS. “We want everyone to understand that this variant is much more easily transmitted, and there is increased risk of rapid spread. Now is the time for people to take additional precautions and limit any potential exposures. Wear your mask, wash your hands, avoid gatherings, and make an appointment for a vaccine when it’s your turn. We all have a role to play in ending this pandemic.” COVID-19 Testing Washtenaw County Health Department is working with the Michigan Department of Health and local partners to provide additional, no-cost COVID-19 testing opportunities. Testing will be available this Sun, Jan 24 from 12:00 to 5:00 pm at Pioneer High School 601 W. Stadium Blvd, Ann Arbor, MI. Pre-registration is available but not required. Ongoing testing options are listed at www.washtenaw.org/covid19test or by using the statewide COVID-19 test locator. Faster spread of COVID-19 illness is a serious concern because the number of people sickened increases so more may become seriously ill or die. Prevent transmission whenever possible. Residents are strongly encouraged to use all effective prevention strategies. Wear a face mask around others Keep at least 6 feet apart from others Clean hands frequently Avoid crowded areas or gatherings Ventilate indoor spaces if around others Seek testing if ill, exposed, or after travel Follow isolation or quarantine guidance if ill, exposed, or waiting on test results Get vaccinated when vaccine becomes available to you https://www.washtenaw.org/CivicAlerts.aspx?AID=1390

USA/MI-MDHHS-UNK165/2021 Washtenaw Co Michigan USA/MI-UM-10037881455/2021 1/18 Ann Arbor Michigan map update https://www.google.com/maps/d/u/1/edit?mid=1aQDSL2LwQFbuoCAg_nIOPK8D-LIJ5MYd&ll=42.255594902151756%2C-83.95974398951249&z=9

USA/MI-MDHHS-UNK164/2021 Washtenaw Co Michigan USA/MI-UM-10037772450/2021 1/11 Ann Arbor Michigan map update https://www.google.com/maps/d/u/1/edit?mid=1aQDSL2LwQFbuoCAg_nIOPK8D-LIJ5MYd&ll=42.255594902151756%2C-83.95974398951249&z=9

Sequences for the two additional Washtenaw County B.1.1.7 have not been released. They will be assigned UNK numbers, which will be updated upon release. USA/MI-MDHHS-UNK164/2021 Washtenaw Co Michigan USA/MI-MDHHS-UNK165/2021 Washtenaw Co Michigan USA/MI-UM-10037772450/2021 1/11 Ann Arbor Michigan USA/MI-UM-10037881455/2021 1/18 Ann Arbor Michigan There are now a total of five cases of the COVID-19 variant B117 in Washtenaw County, health officials said Sunday. https://www.wxyz.com/news/coronavirus/5-total-cases-of-the-covid-19-variant-identified-in-washtenaw-county

United Kingdom (UK) COVID -19 variant identified at long-term care home Jan 23, 2021 Leave a comment SIMCOE MUSKOKA –Genome sequencing on all six COVID-19 samples from a Barrie long-term care home have now been identified as the United Kingdom (UK) variant that has proven to be highly contagious and easily transmitted “The rapid spread, high attack rate and the devastating impact on residents and staff at Roberta Place long-term care home has been heartbreaking for all,” said Charles Gardner, Medical Officer of Health for the Simcoe Muskoka District Health Unit (SMDHU). “Confirmation of the variant, while expected, does not change our course of action. We remain diligent in doing everything we can to prevent further spread.” On Wednesday January 20, SMDHU confirmed that preliminary laboratory testing of six cases had identified a high likelihood that there was a COVID-19 variant of concern. The second test, a whole genome sequencing test, determined the exact COVID-19 variant, the UK B.1.1.7 variant. This variant of concern is more easily transmitted, resulting in much larger numbers of cases in a very rapid fashion. The outbreak at Roberta Place long-term care was first declared on January 8. As of yesterday, Friday, January 22, 124 of 127 residents, and 84 staff were positive for the virus, resulting in 29 deaths. In addition, two essential visitors and three external partners have tested positive. Yesterday the health unit in partnership with the Royal Victoria Regional Health Centre accelerated its immunization program, with its mobile immunization team vaccinating all eligible residents and staff at Roberta Place Retirement Lodge retirement home against COVID-19. Beginning this weekend, the health unit, in collaboration with Royal Victoria Regional Health Centre, (RVH) began immunizing residents at the other retirement homes throughout Simcoe Muskoka. In addition, as of January 16, eligible residents of all long term care facilities in Simcoe Muskoka have received their first dose of immunization against COVID-19. It’s important that everyone continue to strictly follow public health measures to reduce and prevent transmission of the virus: wear a mask, physically distance from those outside your household, wash your hands frequently, leave your home only for essential reasons (in keeping with the provincial Stay at Home Order), and if you have symptoms self-isolate at home and get tested for COVID-19. For more information, visit the health unit’s COVID-19 Vaccine and Immunization web page or call Health Connection to speak with a public health professional weekdays 8:30 a.m. to 6:00 p.m. and Saturdays 8:30 a.m. to 4:30 p.m. at 705-721-7520 (1-877-721-7520). More information about the vaccine and immunization can also be found at ontario.ca. https://www.simcoemuskokahealth.org/HealthUnit/About/Newsroom/2021/01/23/United-Kingdom-(UK)-COVID--19-variant-identified-at-long-term-care-home

COVID-19 variant first seen in U.K. found in Barrie long-term care home, public health unit confirms Only 2 residents at Roberta Place Long-Term Care Home not infected with COVID-19 CBC News · Posted: Jan 23, 2021 11:38 AM ET | Last Updated: 30 minutes ago Genome sequencing has confirmed that a variant of COVID-19 first detected in the United Kingdom is present at a long-term care home in Barrie, Ont., according to the Simcoe Muskoka District Health Unit. (Evan Mitsui/CBC) Genome sequencing has confirmed that a variant of COVID-19 first detected in the United Kingdom is present at a long-term care home in Barrie, Ont., according to the local public health unit. This variant is considered highly contagious and can be transmitted easily. In a news release on Saturday, the Simcoe Muskoka District Health Unit (SMDHU) said the testing done on Friday has determined that six samples taken from the Roberta Place Long Term Care Home are of the variant that is known as the B.1.1.7 variant. The home is north of Toronto. Eighty-four staff members have tested positive for the virus, which Gardner says account for nearly half of the home's staff. Gardner also said there have been 32 deaths as of Saturday. The outbreak was declared on Jan. 8. Two essential visitors and three others have also tested positive. The Canadian Red Cross was deployed to the home on Jan. 17 to help stop the ongoing outbreak. As of Jan. 16, eligible residents of all long-term care facilities in the region have received their first dose of immunization. Officials said they planned to immunize residents at the other retirement homes throughout Simcoe Muskoka over the weekend. Known variant strains of the virus were first detected in the U.K., South Africa and Brazil. https://www.cbc.ca/news/canada/toronto/u-k-variant-roberta-place-1.5885286

Jan 23 B.1.1.7 in LTCF - Barrie, Ontario 124/127 residents symptomatic + 84 staff B.1.1.7 confirmed in 6/6 swabs 29 resident deaths (and counting) https://recombinomics.co/thedrnimanshow/2021/012321_B117_LTCF_Barrie.mp3

USA/NC-CDC-STM-UNK1163/2021 Mecklenburg County North Carolina USA/NC-CDC-STM-0000013-G10/2021 1/11 North Carolina map update https://www.google.com/maps/d/u/1/edit?mid=1aQDSL2LwQFbuoCAg_nIOPK8D-LIJ5MYd&ll=35.28991527878123%2C-81.05959507696316&z=10

The sequence from the Mecklenburg Co case has not been released. It will be give a UNK number, which will be updated when released. USA/NC-CDC-STM-UNK1163/2021 Mecklenburg County USA/NC-CDC-STM-0000013-G10/2021 1/11 North Carolina The North Carolina Department of Health and Human Services said the B.1.1.7 variant was identified in a sample from an adult in Mecklenburg County processed by Mako Medical Laboratories. https://www.wavy.com/news/north-carolina/first-case-of-covid-19-variant-reported-in-nc/

UK variant confirmed at Roberta Place Siobhan MorrisWeekend Producer/Videographer @siomoCTV Contact Published Saturday, January 23, 2021 10:56AM ESTLast Updated Saturday, January 23, 2021 11:26AM EST SHARE BARRIE, ONT. -- Public health officials confirm a new, more easily transmissible variant of COVID-19 first identified in the United Kingdom has torn through Roberta Place Long-Term Care in Barrie. The Simcoe Muskoka District Health Unit says genome sequencing identified the UK B.1.1.7 variant in six swabs taken from the facility. Since an outbreak was declared Jan. 8 , 124 of 127 residents and 84 staff members have been sickened. Twenty-nine residents with the virus have died. Fifty-five cases of COVID-19 were identified in the first 48 hours of the outbreak. The Simcoe Muskoka District Health Unit says genome sequencing identified the UK B.1.1.7 variant in six swabs taken from the facility. "The rapid spread, high attack rate and the devastating impact on residents and staff at Roberta Place long-term care home has been heartbreaking for all," said Medical Officer of Health Charles Gardner. "Confirmation of the variant, while expected, does not change our course of action. We remain diligent in doing everything we can to prevent further spread." Health officials revealed early this week that the home's first positive case was in a staff member who'd had close contact with someone who had recently travelled, though that traveller had not visited regions where new variants have been identified. Residents and staff at the neighbouring Roberta Place Retirement Lodge received their first doses of COVID-19 vaccine Friday. No cases of the virus have been identified at the retirement home. This is a developing story. Check back for updates. https://barrie.ctvnews.ca/uk-variant-confirmed-at-roberta-place-1.5279379

Canada/ON-PHL-21-UNK162/2021 map update https://www.google.com/maps/d/u/1/edit?mid=1aQDSL2LwQFbuoCAg_nIOPK8D-LIJ5MYd&ll=44.34093052435826%2C-79.86361283476563&z=10