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Cruise ship virus infection confirmed 10 people transported to medical institutions in Kanagawa Prefecture February 5, 2020 9:44New type pneumonia A Hong Kong man infected with the new coronavirus is on board and a cruise ship anchored off the port of Yokohama has been tested for viruses such as those with fever symptoms, and so far 31 results have been found It was confirmed that 10 of them were infected with the virus. According to the Ministry of Health, Labor and Welfare, the policy is to have passengers and crew members left on board ships wait in a cabin for 14 days in principle. According to the Ministry of Health, Labor and Welfare, the cruise ship Diamond Princess has been moored off the coast of Daikoku Wharf in Yokohama Port from the night of March 3, and quarantine of about 3,700 passengers and all crew members has been conducted on board. Then, 120 people who had symptoms such as fever and cough, and 153 people who were in close contact with those who had symptoms were collected from 273 people, and virus tests were conducted sequentially. So far, results for 31 people have been identified, and 10 of them have been confirmed to have been infected with the virus. A marine cruise ship is dispatched to the cruise ship, and around 7:30 am, 10 men and women with confirmed infections are transported to multiple medical institutions in Kanagawa Prefecture. There are 4 people in their 50s and 60s, 10 people in their 50s and 60s, and none in their 70s and 80s, and none of them have severe symptoms. Of these, three people in their 50s and 60s are Japanese. is. The company plans to keep the 3,700 passengers and crew members on board for 14 days in principle, waiting in the cabin. The cruise ship left Yokohama last month and visited Hong Kong around Kagoshima, and it was confirmed that an 80-year-old passenger man living in Hong Kong who got off the ship was infected with the new coronavirus. Was. On board According to the cruise ship's passengers, an announcement was made at around 8:10 a.m. on the 5th in the morning. According to the inspection, it was explained that 10 of the passengers and crew had shown a positive reaction. Was instructed to wait at. In addition, passengers and occupants were not allowed to disembark for 14 days in principle, and it was stated that meals would be distributed to all guest rooms through room service. The man said, "There is a possibility that we will not be able to disembark for the foreseeable future. We will also check the luggage packed in the trunk to secure the medicine." According to a woman who is on board with her mother in her 80s, "I can't get off, so I'm having trouble getting my mother's high blood pressure medicine out of the way. What will happen in the future? " PM: "Remaining passengers and crew members stay on board" In this connection, Prime Minister Abe stated at the House of Representatives Budget Committee that he would make every possible effort to prevent the spread of infection, such as by leaving remaining passengers and crew members on board for a certain period of time. Among them, Prime Minister Abe conducted a test for a new type of coronavirus on a cruise ship anchored off the port of Yokohama on people with fever symptoms and found that 10 people had been infected so far. Was explained. He further stated, "These patients will be disembarked and will be hospitalized as a patient under the Infectious Diseases Control Law." "When judging the presence or absence of the new coronavirus only by epidemiological conditions, we will take measures that assume a maximum incubation period of 14 days. Based on this, we will not allow the remaining occupants and passengers to land for the time being And stay on board for as long as necessary ", and continued to make every effort to prevent the spread of infection.

Update on pneumonia of new coronavirus infections as of 24:00 on February 4 2020-02-05 　　At 04:00 on February 4th, 31 provinces (autonomous regions, municipalities) and the Xinjiang Production and Construction Corps reported 3887 newly confirmed cases (3156 cases in Hubei Province), and 431 new severe cases (377 cases in Hubei Province). There were an increase of 65 death cases (65 cases in Hubei Province), 262 newly cured cases (125 cases in Hubei Province), and 3,971 suspected cases (1957 cases in Hubei Province). 　　As of 24:00 on February 4, the National Health and Health Commission has received a total of 24,324 confirmed cases (one reduction in Hainan Province) of confirmed cases, and 3,219 of the severe cases, with cumulative deaths, in 31 provinces (autonomous regions, municipalities) and Xinjiang Production and Construction Corps. There were 490 cases, and 892 cases were cured and discharged (1 case each in Hainan Province and Hubei Province). There are 23260 suspected cases. 　　At present, a total of 252,154 close contacts have been tracked, 18,457 medical observations have been lifted that day, and 185,555 people are currently receiving medical observations. 　　A total of 39 confirmed cases were reported from Hong Kong, Macao and Taiwan: 18 in the Hong Kong Special Administrative Region (1 death), 10 in the Macao Special Administrative Region, and 11 in Taiwan. 　　(Information comes from the official website of the National Health Commission)

3,219 of the severe cases - 490 deaths, and 892 cases were cured and discharged http://www.chinacdc.cn/jkzt/crb/zl/szkb_11803/jszl_11809/202002/t20200205_212241.html

Epidemic situation of new coronavirus infection in Hubei Province on February 4, 2020 From 04:00 to 24:00 on February 4, 2020 , 3156 new pneumonia cases of new coronavirus infection were added in Hubei Province , of which: 1967 in Wuhan, 104 in Huangshi, 27 in Shiyan, 103 in Xiangyang, and Yichang 44 cases, 100 cases in Jingzhou City, 22 cases in Jingmen City, 50 cases in Ezhou City, 342 cases in Xiaogan City, 223 cases in Huanggang City, 36 cases in Xianning City, 65 cases in Suizhou City, 15 cases in Enshi Prefecture, 37 cases in Xiantao City, Tianmen City There were 11 cases and 10 cases in Qianjiang City. There were 65 new deaths in the province , including 49 in Wuhan, 1 in Xiangyang, 1 in Yichang, 2 in Jingzhou, 2 in Jingmen, 1 in Xiaogan, 6 in Huanggang, 2 in Suizhou, One case in Xiantao City. There were 125 new hospital discharges : 65 in Wuhan, 8 in Huangshi, 3 in Shiyan, 6 in Xiangyang, 7 in Yichang, 3 in Jingzhou, 10 in Jingmen, 2 in Ezhou, and Xiaogan There were 2 cases, 11 cases in Huanggang City, 1 case in Xianning City, 6 cases in Suizhou City, and 1 case in Enshi Prefecture. As of 24:00 on February 4, 2020, Hubei Province has reported 16,678 cases of pneumonitis with new type of coronavirus infection , of which: 8351 in Wuhan, 509 in Huangshi, 318 in Shiyan, 735 in Xiangyang, and 496 in Yichang 713 cases in Jingzhou City, 422 cases in Jingmen City, 382 cases in Ezhou City, 1462 cases in Xiaogan City, 1,645 cases in Huanggang City, 384 cases in Xianning City, 706 cases in Suizhou City, 138 cases in Enshi Prefecture, 225 cases in Xiantao City, and 128 cases in Tianmen City There were 54 cases in Qianjiang City and 10 cases in Shennongjia Forest District. 520 patients have been discharged and 479 died, of which: 362 in Wuhan, 2 in Huangshi, 2 in Xiangyang, 4 in Yichang, 9 in Jingzhou, 16 in Jingmen, 18 in Ezhou, and 18 in Xiaogan There were 25 cases in Huanggang City, 8 cases in Suizhou City, 4 cases in Xiantao City, 10 cases in Tianmen City, and 1 case in Qianjiang City. At present , 12627 cases are still being treated in the hospital , of which 1809 cases are critically ill and 711 cases are critically ill. They are all under isolation treatment at designated medical institutions. A total of 81,039 close contacts have been tracked, and 66,764 people are still undergoing medical observation.

520 patients have been discharged and 479 died 1809 cases are severely ill and 711 cases are critically ill http://wjw.hubei.gov.cn/fbjd/dtyw/202002/t20200205_2019293.shtml

In 2003, a 29 nt deletion in orf 8 was associated with increased transmission and virulence which lead to international spread via guests and visitors at the Metropole Hotel.

B.C. confirms second case of novel coronavirus in resident with family visiting from Wuhan BY SIMON LITTLE GLOBAL NEWS Posted February 4, 2020 4:19 pm Updated February 4, 2020 5:20 pm B.C. Chief Medical Health Officer Dr. Bonnie Henry provides an update on the novel coronavirus in British Columbia. British Columbia has announced a second “presumptive confirmed” case of the novel coronavirus. The case will still need to be confirmed by a second test at the National Microbiology Lab in Winnipeg, but health officials say they expect it to return positive. Dr. Bonnie Henry, the province’s chief medical health officer, made the announcement Tuesday, and said the patient was a woman who had contact with family visiting from Wuhan, China. READ MORE: B.C. has tested 114 people for the novel coronavirus, but has only confirmed 1 case Henry said the woman, a resident of the Vancouver Coastal Health (VCH) region, and her family remain at her home, and VCH is following up with the entire group. “The test came back positive yesterday, and Vancouver Coastal is doing the detailed investigations today,” said Henry. “We’ll be testing, we’ll also be making sure that they trace back any movements that these people have had, and make sure we are in contact with anybody that may have had close contact with any of them.”

Medical health officials have identified a second case of coronavirus in BC. It involves a woman who has had family contact with people who have been in Wuhan, China. https://globalnews.ca/news/6506297/bc-top-doctor-novel-coronavirus-update/

Two people, a University of York student and one of their relatives, continue to be treated for coronavirus in the specialist infectious diseases unit at Newcastle Royal Victoria Infirmary. https://www.portsmouth.co.uk/health/coronavirus-hampshire-university-student-returning-china-isolation-after-feeling-unwell-1385126

Two people, a University of York student and one of their relatives, continue to be treated for coronavirus in the specialist infectious diseases unit at Newcastle Royal Victoria Infirmary. https://www.portsmouth.co.uk/health/coronavirus-hampshire-university-student-returning-china-isolation-after-feeling-unwell-1385126

UCSF Health Response on Novel Coronavirus Outbreak UCSF Health has received two patients with confirmed novel coronavirus (2019-nCoV), who were transferred to the hospital from another county in California today, Monday, Feb. 3. The patients are being cared for in isolation at UCSF Health. UCSF, which specializes in the care of patients with complex illnesses, including infectious diseases like the novel coronavirus, also treated patients during past epidemics, such as SARS in 2003. In addition to our standard infectious disease protocols, we have instituted a number of measures to screen patients with potential 2019-nCoV, as well as prevent the coronavirus’ spread. UCSF Health is screening patients to ensure that we are taking all precautions for any individuals that have traveled from China. https://www.ucsf.edu/news/2020/02/416606/ucsf-health-response-novel-coronavirus-outbreak

Two coronavirus patients transferred to UCSF for treatment Published 12 hours ago KTVU FOX 2 Two coronavirus patients transferred to UCSF for treatment Bay Area health officials say two of the California coronavirus patients are recuperating at their homes in Santa Clara County. Meanwhile, UCSF is treating two patients of their own who were transferred from San Benito County. SAN FRANCISCO - San Francisco's Department of Public Health said two patients with the new coronavirus were transferred Monday morning from outside the county to a San Francisco hospital for specialized treatment. In a statement from San Benito County, two patients with novel coronavirus 2019-nCoV showed worsening symptoms late Sunday night. “It was then determined that both patients needed to be admitted to a hospital equipped for a higher level of care. The patients have been transferred out of San Benito County by specialty ambulance,” said Dr. Marty Fenstersheib, the San Benito County Health Officer. The University of California San Francisco confirms they received the two patients and both are being cared for in isolation. They are not disclosing the names of the patients for privacy reasons. A source tells KTVU the patients are being treated at the Parnassus campus. UCSF specialists and experts have a history of treating infectious diseases including cases from the 2003 SARS epidemic. "In addition to our standard infectious disease protocols, we have instituted a number of measures to screen patients with potential 2019-nCoV, as well as prevent the coronavirus’ spread. CSF Health is screening patients to ensure that we are taking all precautions for any individuals that have traveled from China," UCSF Health said in a statement. https://www.ktvu.com/news/two-coronavirus-patients-transferred-to-ucsf-for-treatment

2 Coronavirus Cases Being Treated at UCSF; Chinese New Year Parade is a Go By Pete Suratos • Published February 4, 2020 • Updated 4 hours ago As concerns grow regarding the spread of the coronavirus around the world, local officials are addressing the issue head on. Two cases from San Benito County, a husband and wife, are being treated at UCSF Medical Center in San Francisco, NBC Bay Area has learned. There are 11 confirmed coronavirus cases in the United States. The San Benito County couple caught the virus after the husband traveled to China. His wife contracted the illness from her husband, officials say. They are in isolation at UCSF. Meanwhile, officials around the Bay Area are continuing to address concerns about the coronavirus. San Francisco Mayor London Breed addressed a crowd saying it's safe to celebrate Chinese New Year with this weekend's parade in the city, which usually attracts thousands of https://www.nbcbayarea.com/news/local/2-coronavirus-cases-being-treated-at-ucsf-chinese-new-year-parade-is-a-go/2226755/?_osource=db_npd_nbc_kntv_twt_shr

PRESS RELEASE 2019 Novel Coronavirus Patients Transferred Out of County for Medical Care FOR IMMEDIATE RELEASE Contact: February 3, 2020 Sam Perez, MPH, Public Information Officer Tel: 831-637-5367 _____________________________________________________________________________ San Benito County-Two patients with novel coronavirus in San Benito County showed worsening symptoms late Sunday night and were referred for medical evaluation. “It was then determined that both patients needed to be admitted to a hospital equipped for a higher level of care. The patients have been transferred out of San Benito County by specialty ambulance,” said Dr. Marty Fenstersheib, San Benito County Health Officer. Even with news of this case, the risk to the general public remains low because the patient remained at home. San Benito County residents, students, workers, and visitors should continue to engage in their regular activities and practice good health hygiene since this is the height of flu season. Anyone with respiratory symptoms, such as a cough, sore throat, or fever, should stay home, practice proper cough etiquette and hand hygiene, and limit their contact with other people. San Benito County Public Health Services is working closely with the Centers for Disease Control (CDC) and the California Public Health Department (CDPH), and other partners as this continues to be a rapidly evolving situation. On February 2, 2020, San Benito County Public Health Services activated its Department Operations Center to ensure regular communications to the public, providers and partners, as well as to handle any reports of potential novel coronavirus infection. The department will continue to provide regular updates and to work with healthcare providers as the situation evolves.

Two patients with novel coronavirus in San Benito County showed worsening symptoms late Sunday night and were referred for medical evaluation. “It was then determined that both patients needed to be admitted to a hospital equipped for a higher level of care. The patients have been transferred out of San Benito County by specialty ambulance,” said Dr. Marty Fenstersheib, San Benito County Health Officer. https://hhsa.cosb.us/wp-content/uploads/2020/02/2019-Novel-Coronavirus-Patient-Transferred-Out-of-County-for-Medical-Care-PR02032VF.pdf

Virus detail Virus name: BetaCoV/USA/WA1-A12/2020 Accession ID: EPI_ISL_407214 Type: betacoronavirus Passage details/history: Vero p1 Sample information Collection date: 2020-01-25 Location: North America / USA / Washington Host: human I

Virus detail Virus name: BetaCoV/USA/WA1-F6/2020 Accession ID: EPI_ISL_407215 Type: betacoronavirus Passage details/history: Vero p1 Sample information Collection date: 2020-01-25 Location: North America / USA / Washington Host: human

The University of Washington has released sequences at GISAID from two isolates (BetaCoV/USA/WA1-F6/2020 and BetaCoV/USA/WA1-A12/2020) from the first confirmed nCoV case (35M) from Snohomish County,WA. They match the original sequence which has the orf8 mutation and is the same lineage as sequences from Shenzhen, Chicago, Yorkshire clusters,and other US sequences (from CA and AZ) and other sequences from China (Shenzhen and Wohan) and the first sequence from South Korea.

Virus detail Virus name: BetaCoV/Korea/KCDC03/2020 Accession ID: EPI_ISL_407193 Type: betacoronavirus Passage details/history: Vero P1 Sample information Collection date: 2020-01-25 Location: Asia / Korea / Gyeonggi-do Host: Human

The first nCoV sequence (released at GISAID) from South Korea, BetaCoV/Korea/KCDC03/2020, has the orf8 mutation and is the same lineage as the Shenzhen, Chicago, and Yorkshire clusters, as well as US cases from WA, CA, AZ and additional sequences from China (Wohan and Shenzhen).

This site has map and links to sources https://bnonews.com/index.php/2020/02/the-latest-coronavirus-cases/

Coronavirus: S'pore reports first cases of local transmission; 4 out of 6 new cases did not travel to China Two women who work at Yong Thai Hang (above), a Chinese health products shop in Cavan Road that caters to Chinese tour groups, have come down with the coronavirus, as has a tour guide who led Chinese tourists there.ST PHOTO: KEVIN LIM PUBLISHED 1 HOUR AGO FACEBOOKTWITTER Chang Ai-Lien Science and Health Editor Salma Khalik Senior Health Correspondent SINGAPORE - Singapore has recorded its first cases of local coronavirus transmission, with four women here infected who had not travelled to Wuhan, the epicentre of the outbreak. Two work at Yong Thai Hang, a Chinese health products shop in Cavan Road, in Lavender, that caters to Chinese tour groups. The third is a maid of one of the women, while the fourth is a tour guide who had taken groups to the same shop. The tour group in question has since returned to China. In addition, another two confirmed cases were announced on Tuesday (Feb 4). The two were among a group of 92 people flown back to Singapore from Wuhan on a Scoot flight last Thursday. Before this, another two on the same flight had been reported as confirmed cases. In total, there are now 24 confirmed cases in Singapore.

First four cases of local nCoV transmission - Two work at Yong Thai Hang, a Chinese health products shop in Cavan Road, in Lavender, that caters to Chinese tour groups. The third is a maid of one of the women, while the fourth is a tour guide who had taken groups to the same shop. https://www.straitstimes.com/singapore/coronavirus-spore-reports-first-cases-of-local-transmission-4-out-of-6-new-cases-did-not

Feb 3 PCR confirmed cases jump to 43,652 Hong Kong Death New US Cases in Santa Clara CA (2), Boston MA, San Benito cluster Fake 2.2% CFR talking point SARS re-run on fake CFR CFR for 1st 41 Wuhan cases CFR for first 1,057 outcomes in China England cluster sequences with orf8 mutation Shenzhen and Chicago clusters with orf8 mutation orf8 mutation cited in NEJM on 1st US case (WA) Recombination in Chicago and Los Angeles seqs orf8 mutation in Wuhan, Shenzhen, Phoenix SARS similarity of selection for orf8 mutation German cluster grows to 12 across 6 cities in 3 countries http://mediaarchives.gsradio.net/rense/special/rense_020320_hr3.mp3

Transcript says 11 confirmed cases, which is correct and includes ONE case from Arizona (I suspect CIDRAP correct error for AZ).