niman Posted January 9, 2021 Author Report Posted January 9, 2021 Jan 9 S Dropout Screening Helix/Illumina Many B.1.1.7 in CA & FL 1st in GA & PA Highest & Rising CA, FL, PA https://recombinomics.co/thedrnimanshow/2021/010921_SDrop_Helix.mp3
niman Posted January 9, 2021 Author Report Posted January 9, 2021 Jan 9 S Dropout Screening Helix/Illumina Many B.1.1.7 in CA & FL 1st in GA & PA Highest & Rising CA, FL, PA https://recombinomics.co/thedrnimanshow/2021/010921_SDrop_Helix.mp3
niman Posted January 10, 2021 Author Report Posted January 10, 2021 Jan 10 Variant Japan ex-Brazil RBD matches 501.v2 - South Africa variant NSB6 deletion matches 501.v2/B.1.1.7 501.2 recombinant https://recombinomics.co/thedrnimanshow/2021/011021_Brazil_501v3.mp3
niman Posted January 11, 2021 Author Report Posted January 11, 2021 Jan 11 501.v3/Brazil export to Japan K417T vs K417N in 501.v2 New CDC Seqs 25 CA, 21 FL, 4 MN, 1 GA, 1 PA https://recombinomics.co/thedrnimanshow/2021/011121_501v3_CDCseqs.mp3
niman Posted January 14, 2021 Author Report Posted January 14, 2021 Jan 14 Brazil P.1 Northern Brazil dominance K417T E484K N501Y Immune escape Tuesday record US death toll https://recombinomics.co/thedrnimanshow/2021/011421_Brazil_P1.mp3
niman Posted January 15, 2021 Author Report Posted January 15, 2021 Jan 15 Early Rel MMWR - Variants B.1.1.7 501.v2 P.1 B.1.1.7 with E484K Recombinant https://recombinomics.co/thedrnimanshow/2021/011521_MMWR_E484K.mp3
niman Posted January 16, 2021 Author Report Posted January 16, 2021 Jan 16 Early Rel MMWR - Variants B.1.1.7 501.v2 P.1 B.1.1.7 with E484K Recombinant Updated https://recombinomics.co/thedrnimanshow/2021/011621_MMWR_E484K.mp3
niman Posted January 16, 2021 Author Report Posted January 16, 2021 Jan 16 Explosion in US of UK Variant B.1.1.7 S Dropout 112 case/seqs in 21 states Newer States IL IN LA MI NE NM OK OR UT WI WY https://recombinomics.co/thedrnimanshow/2021/011621_B117_US_Spike.mp3
niman Posted January 16, 2021 Author Report Posted January 16, 2021 Jan 16 Los Angeles 1st Variant B.1.1.7 LA infection USA/CA-UW-63893941/2021 1/8 OR contact USA/OR-UW-63893956/2021 1/8 Both S Dropouts UW sequences https://recombinomics.co/thedrnimanshow/2021/011621_LosAngeles_B117.mp3
niman Posted January 17, 2021 Author Report Posted January 17, 2021 Jan 16 Los Angeles exports B.1.1.7 to Oregon B.1.1.7 ID'ed by UW using S dropout Is LA using S Dropout to find B.1.1.7? https://recombinomics.co/thedrnimanshow/2021/111621_LA_Sans_SDropout.mp3
niman Posted January 19, 2021 Author Report Posted January 19, 2021 Jan 19 FL 24 new B.1.1.7 FL total 46 - highest in US No transparency Helix dropout program most in US L452R probably not a true variant https://recombinomics.co/thedrnimanshow/2021/011921_SDropout_FL.mp3
niman Posted January 20, 2021 Author Report Posted January 20, 2021 Jan 20 B.1.1.7 Sequences - CA FL CA = 77 seqs FL = 49 segs All S Dropouts (SGTF) by Helix More B.1.1.7 with E484K CA new variant NOT https://recombinomics.co/thedrnimanshow/2021/012021_CA_FL_SGTF (1).mp3
niman Posted January 23, 2021 Author Report Posted January 23, 2021 Jan 23 B.1.1.7 in LTCF - Barrie, Ontario 124/127 residents symptomatic + 84 staff B.1.1.7 confirmed in 6/6 swabs 29 resident deaths (and counting) https://recombinomics.co/thedrnimanshow/2021/012321_B117_LTCF_Barrie.mp3
niman Posted January 24, 2021 Author Report Posted January 24, 2021 Jan 23 Yale SGTF testing B.1.1.7 positives IL - 8 NJ - 6 NY - 1 CT - 1 U Mich athletics halted - cluster 10-15 & counting https://recombinomics.co/thedrnimanshow/2021/012332_Yale_SGTF.mp3
niman Posted January 24, 2021 Author Report Posted January 24, 2021 Jan 24 Variant Evolution Common elements in UK, South Africa, Brazil Enhanced trans D614G, N501K Immune Escape NTD changes, RBD E484K Evolve in immunosuppressed https://recombinomics.co/thedrnimanshow/2021/012421_Variant_Evol.mp3
niman Posted January 27, 2021 Author Report Posted January 27, 2021 Jan 26 Robert Place Update Resident deaths at 46 Caretaker death 1 Bradford Waypoint Little surveillance https://recombinomics.co/thedrnimanshow/2021/012621_Barrie_Update.mp3
niman Posted January 28, 2021 Author Report Posted January 28, 2021 (edited) Jan 27 Barrie - Roberta Place B.1.1.7 50 deaths 128/129 residents + 86 staff 85 primary contacts 5 caretaker/visitors 304 total https://recombinomics.co/thedrnimanshow/2021/012721_Barrie_50_Deaths.mp3 Edited January 28, 2021 by niman
niman Posted January 28, 2021 Author Report Posted January 28, 2021 Jan 28 501.v2 (B.1.351) in SC 1st detections in US Lowcounty & Pee Dee No travel or linkage SC-DHEC & LabCorp/CDC independent Vaccine resistant https://recombinomics.co/thedrnimanshow/2021/012821_B1351_US.mp3
J Enders Posted January 29, 2021 Report Posted January 29, 2021 The last few updates including today have an audio problem either in the recording or on playback they become unlistenable about halfway to 3/4 of the way in. It would be great if that could be addressed because we’d love to hear the entire update.
niman Posted January 29, 2021 Author Report Posted January 29, 2021 Jan 29 JNJ Vaccine 501.v2 escape U Mich outbreak --> 18 cases Wayne Co distinct ---> 6+2 cases https://recombinomics.co/thedrnimanshow/2021/012921_MI_Vaccines.mp3
niman Posted January 29, 2021 Author Report Posted January 29, 2021 The last few updates including today have an audio problem either in the recording or on playback they become unlistenable about halfway to 3/4 of the way in. It would be great if that could be addressed because we’d love to hear the entire update. A listener suggested dust may be to blame and after vacuuming my keyboard, today's commentary (10:45 min) was clear. 1
niman Posted January 30, 2021 Author Report Posted January 30, 2021 (edited) Jan 30 South Africa variant (501.v2 B.1.351) in Maryland Sequence by Johns Hopkins Pathology Jan 21 collection Deposited at GISAID last night https://recombinomics.co/thedrnimanshow/2021/013021_MD_501v2.mp3 Edited January 30, 2021 by niman
niman Posted January 30, 2021 Author Report Posted January 30, 2021 Jan 30 South Africa variant (501.v2 B1.351) Maryland update Baltimore metro with no recent travel Likely variant is widespread on US east coast Time for customized S dropout / SGTF test Vaccine resistant (E484K) https://recombinomics.co/thedrnimanshow/2021/013021_MD2_B1351.mp3
niman Posted February 1, 2021 Author Report Posted February 1, 2021 Feb 1 Florida has 147 B.1.1.7 cases per CDC update Friday was at 125 No detail on cases Top counties for first 92 were Miami-Dade and Broward Seqs released = 93 - vast majority by Helix https://recombinomics.co/thedrnimanshow/2021/020121_FL_147.mp3
niman Posted February 2, 2021 Author Report Posted February 2, 2021 Feb 1 Roberta Place - Resident deaths increase to 63 (128/129 PCR conf) 267 outbreak related cases listed 19 seqs B.1.1.7 confirmed 124 N501Y positive 39 Confirmed in York B.1.351 in Mississauga https://recombinomics.co/thedrnimanshow/2021/020121_RobertaP.mp3
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