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Thai airport detects coronavirus infection #Asia #Health & Welfare #China 2 hours ago Thailand's public health ministry says it has found a tourist from the Chinese city of Wohan infected with the new coronavirus. The inland city has been hit by a pneumonia outbreak that is likely caused by the virus. The ministry says the 61-year-old woman had a fever of over 38 degrees Celsius as well as respiratory problems upon her arrival at a Thai airport last Wednesday. She was on a group tour from the city in Hubei Province. After being hospitalized, she was confirmed on Sunday to have been infected with the new coronavirus. Ministry officials say she is recovering. Airports in Thailand are equipped with special imaging cameras that can detect human body temperatures. In response to an outbreak of viral pneumonia in China, Thai officials say they have been closely checking passengers arriving from Wohan since January 3. https://www3.nhk.or.jp/nhkworld/en/news/20200113_24/

CHINA JANUARY 13, 2020 / 8:22 AM / UPDATED AN HOUR AGO Chinese woman with mystery virus quarantined in Thailand 3 MIN READ BANGKOK (Reuters) - A Chinese woman has been quarantined in Thailand with a mystery strain of coronavirus, authorities said on Monday, the first time it has been detected outside China. Thai authorities are stepping up monitoring at airports ahead of the Lunar New Year holiday, beginning on Jan. 25, when hundreds of thousands of Chinese tourists are expected to visit. A 61-year-old man died from pneumonia, a symptom of the disease, in the central Chinese city of Wuhan after an outbreak of the yet to be identified virus. In total, 41 cases of pneumonia have been reported in China, which preliminary lab tests cited by Chinese state media show could be from a new type of coronavirus. Coronaviruses are a large family of viruses that can cause infections ranging from the common cold to SARS. Some of the virus types cause less serious disease, while some like the one that causes MERS, are far more severe. The Wuhan Municipal Health Commission said on Monday seven of the 41 had been discharged and six were in a serious condition. The Thai Health Ministry said on Monday that of 12 passengers quarantined since Jan. 3, lab results show that a 61-year-old Chinese woman carried a strain of the coronavirus. The woman, who was quarantined on Wednesday, had received treatment and was well enough to return home, the ministry said. “Being able to identify a patient shows that there is efficiency in our monitoring system. We are confident that we can manage the situation,” Public Health Minister Anutin Charnvirakul told reporters. Officials in China and Thailand are working with the World Health Organization. The Chinese outbreak appeared to be linked to a single seafood market in Wuhan and had not so far spread beyond there, the WHO said. “The possibility of cases being identified in other countries was not unexpected, and reinforces why WHO calls for on-going active monitoring and preparedness in other countries,” its statement said. WHO Director-General Tedros Adhanom Ghebreyesus will consult with international experts to assess the public health risks of outbreaks and decide whether an emergency meeting is needed, it said. Reporting by Panarat Thepgumpanat and Chayut Setboonsarng; Additional reporting by Stephanie Nebehay and by Vincent Lee; Editing by Nick Macfie and Alison Williams Our Standards:The Thomson Reuters Trust Principles. https://uk.reuters.com/article/uk-china-health-pneumonia-thailand/chinese-woman-with-mystery-virus-quarantined-in-thailand-idUKKBN1ZC1C5

Monday, January 13, 2020, 18:28 Thailand says new coronavirus found in traveler from China By Bloomberg This undated photo shows the Huanan seafood wholesale market linked to the mysterious pneumonia outbreak in the central Chinese city of Wuhan. (PHOTO / CCTV) A traveler from China who arrived in Bangkok was infected with the newly identified virus believed to have triggered a pneumonia outbreak in central China, Thai officials said. The patient, who was hospitalized on Jan. 8 at the Bamrasnaradura Infectious Diseases Institute, tested positive for the novel coronavirus linked to the outbreak in Wuhan, in Hubei province, the Thai Ministry of Public Health said in a statement Monday. The patient has since recovered and is well enough to be repatriated. It’s the first reported case of someone outside China being infected with the novel virus, which has captured international attention because of similarities with the one that sparked Severe Acute Respiratory Syndrome, or SARS, 17 years ago. Unlike SARS, which killed almost 800 people, the new virus doesn’t appear to spread easily between people. “I’d like to ask the public not to be alarmed,” Anutin Charnvirakul, Thailand’s deputy premier and health minister, said in the statement. “The detection of the patient shows that we have an efficient system of surveillance. We’re confident that we can control the situation.” No new related pneumonia cases have been detected in China since Jan. 3, the municipal health commission in the city of Wuhan said Saturday. Genetic studies of virus material collected from patients indicated that 41 people had been infected with the novel coronavirus, instead of the 59 previously counted, it said Sunday. Among the Chinese cases, seven were in serious condition and six were discharged. A 61-year-old man died, although doctors said he also suffered from an abdominal tumor and chronic liver disease. Seafood Market The outbreak was linked to a wholesale seafood market in Wuhan that also sold live animals and meat from wildlife. That had prompted concern that an infectious respiratory pathogen from animals had emerged, potentially setting off a deadly contagion reminiscent of SARS. So far, no infections among health-care workers have been reported, and there is no clear evidence of human-to-human transmission, the World Health Organization said Sunday. The outbreak started in late 2019. “It is too early to breathe a collective sigh of relief, as tempting as it may be,” the International Society for Infectious Diseases’ ProMED-mail program, an internet service to identify unusual health events, said in an email Monday. Scientists still don’t know the source of the virus, and it’s possible it might lurk in animals sold at other markets in China, ProMED-mail said. “We still do not know the host or possible intermediary host of this virus,” it said. “And with the coming Chinese New Year (Jan. 25), there will be massive population movement in the country and the region, and wildlife meals are delicacies.” ALSO READ: Evaluater says new coronavirus caused Wuhan pneumonia Gene Sequence Genomic data pertaining to the novel virus was made publicly available by a team of doctors and researchers in Wuhan, Shanghai, Beijing and Sydney, enabling scientists outside China to study its genetic fingerprint for clues about where and how it might have emerged. Researchers from other cities have been invited to Wuhan to exchange information. Coronaviruses are a large family of respiratory viruses that can cause diseases ranging from the common cold to SARS or the Middle-East Respiratory Syndrome, or MERS-cov, the WHO said. Andrew Rambaut, a professor of molecular evolution at the University of Edinburgh, said the novel coronavirus is 89% similar to a SARS-related bat coronavirus. “But that doesn’t mean it comes from bats,” he said in a post on Twitter. Pig Virus Linfa Wang, a professor and director of the emerging infectious diseases program at the Duke-NUS Medical School in Singapore, said he was traveling to Wuhan Tuesday. Two scientists from Taiwan’s Centers for Disease Control will also visit the city “within days,” Chou Jih-haw, director general of the center, told the South China Morning Post on Sunday. READ MORE: China to share virus genome sequence as 1 dead in Wuhan Wang and colleagues showed in April 2018 that a novel bat coronavirus caused acute diarrhea in pigs, leading to a large-scale outbreak that killed almost 25,000 piglets on four farms in southern China’s Guangdong province from 2013 to 2016. While that particular virus isn’t known to infect humans, coronaviruses cause illness in people more frequently than previously thought, said Wang. It’s only when they cause large clusters of cases, like in Wuhan, that they are investigated and discovered, he said in a phone interview on Tuesday. “This whole investigation is almost like SARS No. 2,” Wang said. “The only difference is that there were no health-care workers infected. Everything else looked just like SARS.” https://www.chinadailyhk.com/article/118311#Thailand-says-new-coronavirus-found-in-traveler-from-China

Home/ News/ Detail/ Thailand responding to the novel coronavirus Credits Thailand responding to the novel coronavirus 13 January 2020 News release Current situation: On January 13, 2020, The Ministry of Public Health of Thailand reported an imported case of infection caused by the novel coronavirus recently identified in Wuhan, China. The concerned individual is a Chinese national who was found to have fever on arrival at Suvarnabhumi airport on 8th January. A clinical diagnosis of mild pneumonia was made after referral to a government hospital. Laboratory testing subsequently confirmed that the novel coronavirus was the cause. WHO acknowledges the capacity of Thailand’s laboratories to do the complex genetic analyses necessary to confirm the diagnosis. Background: Since early December, a number of cases of pneumonia have been detected in persons from Wuhan city in China. Chinese authorities identified a new coronavirus as the agent causing these cases. Coronaviruses are common - many cause less severe illness such as the common cold; other are known to cause more severe illness (SARS and Middle East Respiratory Syndrome, MERS). Chinese scientists have sequenced and made available the genetic material of this virus – a remarkable achievement in such a short time. This will be critical to helping public health authorities around the world understand this illness and track it. The way these patients became infected is not yet known. To date, there has been no suggestion of human to human transmission of this new coronavirus. There have been no infections reported among health care workers, which can be an early indicator of person to person spread. At present, WHO does not recommend any specific health measures for travelers in relation to this event. WHO advises against the application of any travel or trade restrictions on China based on the information available. If travelers develop respiratory illness before, during or after travel, they should seek medical attention and share travel history with their health care provider. The World Health Organization is working with Thailand and other countries to track further understand infections caused by this new coronavirus and to ensure that they are prevented and controlled. This includes, Providing all countries with a technical package of interim guidance, including Common case definitions to ensure patients are identified quickly; Information on laboratory methodologies to identify this and other respiratory viruses, Guidance on how to protect health care workers and others; Guidance on clinical management is being quickly reviewed by global experts and will be shared once available. Facilitating information sharing on this and other relevant health events between countries In the longer term, using the International Health Regulations to develop and strengthen the capacities of countries to detect and respond to infections like the new coronavirus. https://www.who.int/thailand/news/detail/13-01-2020-thailand-responding-to-the-novel-coronavirus#.XhxYMSVyQZU.twitter

Virus detail Virus name: BetaCoV/Wuhan/IVDC-HB-01/2019 Accession ID: EPI_ISL_402119 Type: betacoronavirus Passage details/history: Virus Isolate, Passage 1 Sample information Collection date: 2019-12-30 Location: China / Hubei Province / Wuhan City Host: Human Additional location information:

Virus detail Virus name: BetaCoV/Wuhan/IVDC-HB-04/2020 Accession ID: EPI_ISL_402120 Type: betacoronavirus Passage details/history: Original Sample information Collection date: 2020-01-01 Location: China / Hubei Province / Wuhan City Host: Human Additional location information:

Virus detail Virus name: BetaCoV/Wuhan/IVDC-HB-05/2019 Accession ID: EPI_ISL_402121 Type: betacoronavirus Passage details/history: Original Sample information Collection date: 2019-12-30 Location: China / Hubei Province / Wuhan City Host: Human

Virus name: BetaCoV/Wuhan/IPBCAMS-WH-01/2019 Accession ID: EPI_ISL_402123 Type: betacoronavirus Passage details/history: Original Sample information Collection date: 2019-12-24 Location: China / Hubei Province / Wuhan City Host: Human

Accession ID: EPI_ISL_402124 Type: betacoronavirus Passage details/history: Original Sample information Collection date: 2019-12-30 Location: China / Hubei Province / Wuhan City Host: Human Additional location information: Additional host information: Outbreak: 2019-12-27

Kanawat Chantaralawan is at กระทรวงสาธารณสุข จังหวัดนนทบุรี. 6 hrs · Nonthaburi, Thailand · พบแล้ว ผู้ป่วยนักท่องเที่ยวชาวจีนที่ติดเชื้อ Coronavirus สายพันธุ์ใหม่ ซึ่งเป็นสายเดียวกับที่เมือง อู่หั่น ประเทศจีน ปัจจุบันมีผู้ป่วยที่ต้องเข้าเกณฑ์สืบสวน 12 ราย และ 1 รายที่ตรวจเชื้อยืนยันแล้ว นอกจากนี้ จนท.ยังสืบถึงผู้ที่สัมผัสใกล้ชิดคนอื่นๆเรียบร้อยแล้ว และไวรัสนี้ ยังไม่พบว่ามีการติดต่อจากคนสู่คน เชื้อนี้สามารถทำให้เกิดอาการปอดบวม ซึ่งกลุ่มเสี่ยงส่วนใหญ่ คือ ผู้สูงอายุและเด็กๆ พวกเราต้องคอยสอดส่องและเฝ้าระวังครับ ที่สำคัญที่สุด ตื่นตัว...แต่อย่าตื่นตระหนกครับ เวลาแบบนี้มักมีผู้แสวงหาประโยชน์ พวกเราควรรับฟังข่าวจากทางการดีที่สุดครับ ช่วงเวลานี้จะเป็นช่วงพิสูจน์ความสามารถของพวกเราคนไทยอีกครั้ง การท่องเที่ยวซึ่งเป็น 1 ในตัวหลักในการขับเคลื่อนเศรษฐกิจเรา ในภาวะเศรษฐกิจแบบนี้ อาจจะได้รับผลกระทบ พวกเราต้องช่วยกันครับ คอยระมัดระวัง สอดส่อง รวมถึงเป็นเจ้าบ้านที่ดีต่อครับ ปล. กินร้อน ช้อนกลาง ล้างมือบ่อยๆ นะครับ We have found the new coronavirus Chinese tourist patient who is the same line as the city of China. Now, there are 12 patients who need to investigate 12 investigations and 1 verified people. Also, officer. Still investigating those who have touched the others, and this virus has not yet found a contact from people to people. This Malays can cause pneumonia which most risk groups are elderly and children. We must watch and watch out. Most importantly, stay awake... but don't panic. Time like this always have a seeker. We should listen to the news from the best. This time will prove our ability to Thai people again. Tourism which is 1 in the main one to drive our economy in. This kind of economy may be affected. We need to help each other. Stay vigilant and be a good host. PS. Eat Hot, Medium Spoon, wash your hands often.

Thailand found a new strain of corona virus from China Volume 90% 00:18 00:18 Thailand found a new strain of corona virus from China ingeneral 13 Jan 2020 00:02:15 FACEBOOK MESSENGER WHATSAPP Ministry of Public Health, 13 January - Thailand found corona virus patients A new chain from China comes from a 61-year-old Chinese female woman who can't confirm being in Thailand. Do not transmit human to human Deputy Minister and Public Health Minister Anutin Charnwirakul said that a new strain of corona virus is currently found in patients. From wuhan city People's Republic of China By being a 61 year old female Chinese tourist, able to screen from the airport Found that initially had fever As for those who are close to 16 people, normal symptoms are expected soon. Will be able to return to the country within 3 days because now there are no respiratory symptoms, fever has subsided and then healed in the Bamrasnaradura Institute Confirmation of this patient encounter is not a local contact. But is contacting from China. - Thai News Agency https://www.mcot.net/viewtna/5e1bf9d7e3f8e40af94104e9

Saksith Saiyasombut @SaksithCNA The Thai Public Health Ministry reports the first case of Wuhan Coronavirus outside of China and first one in Thailand. The patient arrived from Wuhan in BKK last week, was put under quarantine, but has already recovered and "ready to go home". 2:43 AM · Jan 13, 2020·Tweetbot for Mac

New SARS-like virus found in traveller from China, says Thailand Bloomberg - January 13, 2020 6:03 PM 99Shares 94 Patient tested positive for the novel coronavirus linked to the outbreak in Wuhan. (Twitter pic/dr_foda) BANGKOK: A traveller from China who arrived in Bangkok was infected with the newly identified virus believed to have triggered a pneumonia outbreak in central China, Thai officials said. The patient, who was hospitalised on Jan 8 at the Bamrasnaradura Infectious Diseases Institute, tested positive for the novel coronavirus linked to the outbreak in Wuhan, in Hubei province, the Thai Ministry of Public Health said in a statement Monday. The patient has since recovered and is well enough to be repatriated. It’s the first reported case of someone outside China being infected with the novel virus, which has captured international attention because of similarities with the one that sparked Severe Acute Respiratory Syndrome, or SARS, 17 years ago. Unlike SARS, which killed almost 800 people, the new virus doesn’t appear to spread easily between people. “I’d like to ask the public not to be alarmed,” Anutin Charnvirakul, Thailand’s deputy premier and health minister, said in the statement. “The detection of the patient shows that we have an efficient system of surveillance. We’re confident that we can control the situation.” No new related pneumonia cases have been detected in China since Jan 3, the municipal health commission in the city of Wuhan said Saturday. Genetic studies of virus material collected from patients indicated that 41 people had been infected with the novel coronavirus, instead of the 59 previously counted, it said Sunday. Among the Chinese cases, seven were in serious condition and six were discharged. A 61-year-old man died, although doctors said he also suffered from an abdominal tumour and chronic liver disease. Seafood market The outbreak was linked to a wholesale seafood market in Wuhan that also sold live animals and meat from wildlife. That had prompted concern that an infectious respiratory pathogen from animals had emerged, potentially setting off a deadly contagion reminiscent of SARS. So far, no infections among health-care workers have been reported, and there is no clear evidence of human-to-human transmission, the World Health Organisation said Sunday. The outbreak started in late 2019. “It is too early to breathe a collective sigh of relief, as tempting as it may be,” the International Society for Infectious Diseases’ ProMED-mail programme, an internet service to identify unusual health events, said in an email Monday. Scientists still don’t know the source of the virus, and it’s possible it might lurk in animals sold at other markets in China, ProMED-mail said. “We still do not know the host or possible intermediary host of this virus,” it said. “And with the coming Chinese New Year (Jan 25), there will be massive population movement in the country and the region, and wildlife meals are delicacies.” Gene sequence Genomic data pertaining to the novel virus was made publicly available by a team of doctors and researchers in Wuhan, Shanghai, Beijing and Sydney, enabling scientists outside China to study its genetic fingerprint for clues about where and how it might have emerged. Researchers from other cities have been invited to Wuhan to exchange information. Coronaviruses are a large family of respiratory viruses that can cause diseases ranging from the common cold to SARS or the Middle-East Respiratory Syndrome, or MERS-COV, the WHO said. Andrew Rambaut, a professor of molecular evolution at the University of Edinburgh, said the novel coronavirus is 89% similar to a SARS-related bat coronavirus. “But that doesn’t mean it comes from bats,” he said in a post on Twitter. Pig virus Linfa Wang, a professor and director of the emerging infectious diseases programme at the Duke-NUS Medical School in Singapore, said he was travelling to Wuhan Tuesday. Two scientists from Taiwan’s Centres for Disease Control will also visit the city “within days,” Chou Jih-haw, director-general of the centre, told the South China Morning Post on Sunday. Wang and colleagues showed in April 2018 that a novel bat coronavirus caused acute diarrhoea in pigs, leading to a large-scale outbreak that killed almost 25,000 piglets on four farms in southern China’s Guangdong province from 2013 to 2016. While that particular virus isn’t known to infect humans, coronaviruses cause illness in people more frequently than previously thought, said Wang. It’s only when they cause large clusters of cases, like in Wuhan, that they are investigated and discovered, he said in a phone interview on Tuesday. “This whole investigation is almost like SARS No 2,” Wang said. “The only difference is that there were no health-care workers infected. Everything else looked just like SARS.” https://www.freemalaysiatoday.com/category/world/2020/01/13/new-sars-like-virus-found-in-traveller-from-china-says-thailand/

First Coronavirus 2019 patient found in Thailand National Jan 13. 2020 By The Nation The Public Health Ministry has found the first patient infected with the new Coronavirus 2019 in Thailand – a 61-year-old Chinese woman from Wuhan city. However, the condition of the patient is not severe and she is ready to return to her homeland. Public Health Minister Anutin Charnvirakul said today (January 13) that Thailand has implemented measures for screening patients travelling from Wuhan city since January 3 at Suvarnabhumi Airport, Don Mueang, Phuket and Chiang Mai airports, and stepped up surveillance at public and private hospitals. There are 12 patients that showed signs of the condition but most have seasonal influenza. Eight patients with a high fever were detected by a thermo-scan at Suvarnabhumi Airport and treated in a separation room at the Bamrasnaradura Infectious Diseases Institute since January 8. A laboratory test on January 12 discovered the new Coronavirus, the first case in Thailand. The patient has been healed was ready to return to China today (January 13). Anutin asked the public not to panic as the ministry has the potential to tackle any crisis. The ministry has international-standard diagnosis and medical care and is closely coordinating with the World Health Organisation and all related departments within the airports to build trust among citizens and tourists, he said. If people returning from the epidemic area experience within 14 days a fever, sore throat, nasal discharge, coughing, phlegm or wheezing, ask to see a doctor immediately or notify the Department of Disease Control via hotline 1422. https://www.nationthailand.com/news/30380478

Coronavirus-infected Chinese tourist being treated in Thailand PUBLISHED : 13 JAN 2020 AT 16:02 WRITER: ONLINE REPORTERS 44 1 Public Health Minister Anutin Charnvirakul, second right, shows visitors from Wuhan receiving health screening at Suvarnabhumi airport in Samut Prakan province on Jan 5. He said on Monday that a Chinese woman found infected with a new strain of coronavirus was in quarantine and being treated in Nonthaburi province. (Photo by Pornprom Satrabhaya) A Chinese tourist was found to be infected with the new strain of coronavirus when she arrived in Thailand, is being treated in hospital and is expected to be discharged in a few days, Public Health Minister Anutin Charnvirakul said on Monday. Mr Anutin said the 61-year-old woman was recovering at Bamrasnaradura Infectious Diseases Institute in Nonthaburi province. She now had no fever or any respiratory symptoms. If doctors gave her a clearance she would be allowed to go home in a few days, said Mr Anutin. Sixteen other people who were close to the woman on the same flight were examined, and the results were negative, he said. Mr Anutin said 59 people in China have been confirmed infected with the new strain of the coronavirus, which has been linked to a sudden outbreak of pneumonia in central China. One of them died. All had attended big markets selling animals and seafood in Wuhan city. They were either workers or buyers. There had not been any human-to-human transmission of the virus. The ill Chinese woman was the first person detected with the virus outside China. Her discovery and successful treatment was indicative of the efficiency and effectiveness of health services in Thailand, Mr Anutin said. Health officials have been checking passengers from Wuhan arriving at Suvarnabhumi, Don Mueang, Phuket and Chiang Mai airports since Jan 3. They had found 12 ill passengers who justified being quarantined. Eight had so far been treated and discharged from hospital. The Chinese woman was being was treated in an isolation ward. Her infection with the new coronavirus was confirmed on Sunday, Mr Anutin said. The Public Health Ministry had not found anyone else infected with it, he said. One of Wuhan’s largest meat and seafood markets was pinpointed as the centre of the mysterious pneumonia outbreak and was shut down on Jan. 1. The man who died had been a customer at that market. Chinese scientists identified the new virus strain last week. Coronaviruses are not necessarily life-threatening but have been the underlying cause of public health crises, including severe acute respiratory syndrome, or SARS, which killed hundreds of people after an outbreak in southern China in 2002 and 2003. The Wuhan viral outbreak seems to be less virulent and less transmittable, according to the World Health Organisation. https://www.bangkokpost.com/thailand/general/1834789/coronavirus-infected-chinese-tourist-being-treated-in-thailand

A Chinese tourist was found to be infected with the new strain of coronavirus when she arrived in Thailand, is being treated in hospital and is expected to be discharged in a few days, Public Health Minister Anutin Charnvirakul said on Monday. https://www.bangkokpost.com/thailand/general/1834789/coronavirus-infected-chinese-tourist-being-treated-in-thailand

This thread will tally novel Coronavirus (2019-nCoV) cases in Thailand. First confirmed case outside of mainland China (61F) was reported today in media reports.

Alignment match for ORF8 Query 1 MKFLVFLGIITTVAAFHQECSLQSCTQHQPYVVDDPCPIHFYSKWYIRVGARKSAPLIELCVDEAGSKSPIQYIDIGNYTVSCLPFTINCQEPKLGSLVVRCSFYEDFLEYHDVRVVLDF 120 AVP78037.1 1 .........L...............A.................R....................V..................S...................Y.........I...... 120 AHX37565.1 1 ..L.IVF.LL.I.YGM.K..TI.E.CEN...ILE......Y..D..LKI.P....R.LQ..AG.Y.KRL.V..EKL....IN.E..E....T.PV...I....YDY..I........... 120 ACU31043.1 1 ..L.IV..LL.S.YCM.K...I.E.CEN..FQLE......Y..D.FLKI.P....R.VQ..AG.Y.HRV..H.EMF....I..E..E....N.PV...I....YDV..M........... 120 AGZ48814.1 1 ..L.IV..LL.S.YCM.K...I.E.CEN..FQLE......Y..D.F.KI.P....R.VQ..AG.Y.HRV..H.EMF....I..E.LE....N.PV...I....YDV..M........... 120 AGZ48826.1 1 ..L.IV..LL.S.YCM.K...I.E.CEN..FQLE......Y..D.FVKI.P....R.VQ..AG.Y.HRV..H.EMF....I..E.LE....N.PV...I....YDV..M........... 120 ALK02466.1 1 ..L.IV..LL.S.YCM.K...I.E.CEN..FQPE......Y..D.FVKI.P....R.VQ..AG.Y.HRV..H.EMF....I..E.LE....N.PV...I....YDV..M........... 120 ATO98239.1 1 ..L.IV..LL.S.YCV.K...I.E.CEN..FQPE......Y..D.FVKI.P....R.VQ..AG.Y.RRV..H.EMF....I..E.LE....N.PV...I....YDV..M........... 120 ATO98189.1 1 ..L.IV..LL.S.YCM.K...I.E.CEN..FQPE......Y..D.FVKI.P....R.VQ..AG.Y.HRV..H.EMF....I..E.LE....N.PV...I....YDV..MD.......... 120 Q3LZX5.1 1 ..L.IVF.LLAS.YC..R...I.E.CEN...QIE......Y..D.F.KI.S....R.VQ..EGDY.RRI..H.EMF....I..E.LE....A.PV...I....YDY..V.H......... 120 ATO98227.1 1 ..L.IV..LL.S.YCM.K...I.E.CEN.SFQLE......Y..D.FVKI.P....R.VQ..AG.Y.HRV..H.EMF....I..E.LE....N.PV...I....YDV..M........... 120

LOCUS AVP78037 121 aa linear VRL 28-MAR-2018 DEFINITION hypothetical protein [Bat SARS-like coronavirus]. ACCESSION AVP78037 VERSION AVP78037.1 DBSOURCE accession MG772933.1 KEYWORDS . SOURCE Bat SARS-like coronavirus ORGANISM Bat SARS-like coronavirus Viruses; ssRNA viruses; ssRNA positive-strand viruses, no DNA stage; Nidovirales; Coronaviridae; Coronavirinae; Betacoronavirus. REFERENCE 1 (residues 1 to 121) AUTHORS Hu,D. TITLE Genomic Characterization and Infectivity of A Novel SARS-like coronavirus in Chinese Bats JOURNAL Unpublished REFERENCE 2 (residues 1 to 121) AUTHORS Hu,D. TITLE Direct Submission JOURNAL Submitted (05-JAN-2018) Institute of Military Medicine Nanjing Command, Nanjing, Institute of Military Medicine Nanjing Command, Nanjing, NO. 293 East Zhongshan Road, Nanjing, JangSu 210002, China FEATURES Location/Qualifiers source 1..121 /organism="Bat SARS-like coronavirus" /isolate="bat-SL-CoVZC45" /host="Rhinolophus sinicus" /db_xref="taxon:1508227" /country="China" /collection_date="Feb-2017" Protein 1..121 /product="hypothetical protein" /name="protein 10b" Region 1..118 /region_name="Corona_NS8" /note="Coronavirus NS8 protein; pfam12093" /db_xref="CDD:152528" CDS 1..121 /coded_by="MG772933.1:27799..28164" ORIGIN 1 mkflvflgil ttvaafhqec slqscaqhqp yvvddpcpih fysrwyirvg arksapliel 61 cvdevgsksp iqyidignyt vscspftinc qepklgslvv rcsyyedfle yhdirvvldf 121 i

Top 10 protein matches for ORF 8 AlignmentsDownloadGenPeptGraphicsDistance tree of resultsMultiple alignmentShow/hide columns of the table presenting sequences producing significant alignments Sequences producing significant alignments: Select for downloading or viewing reports Description Max Score Total Score Query Cover E value Per. Ident Accession Select seq gb|AVP78037.1| hypothetical protein [Bat SARS-like coronavirus] 242 242 100% 8e-81 94.21% AVP78037.1 Select seq gb|AHX37565.1| protein 10b [Rhinolophus affinis coronavirus] 168 168 100% 2e-51 57.85% AHX37565.1 Select seq gb|ACU31043.1| hypothetical protein [SARS coronavirus Rs_672/2006] 164 164 100% 3e-50 58.68% ACU31043.1 Select seq gb|AGZ48814.1| hypothetical protein [Bat SARS-like coronavirus RsSHC014] 164 164 100% 9e-50 58.68% AGZ48814.1 Select seq gb|AGZ48826.1| hypothetical protein [Bat SARS-like coronavirus Rs3367] 163 163 100% 1e-49 57.85% AGZ48826.1 Select seq gb|ALK02466.1| hypothetical protein [SARS-like coronavirus WIV16] 162 162 100% 4e-49 57.85% ALK02466.1 Select seq gb|ATO98239.1| ORF8 [Bat SARS-like coronavirus] 161 161 100% 6e-49 57.85% ATO98239.1 Select seq gb|ATO98189.1| ORF8 [Bat SARS-like coronavirus] 160 160 100% 2e-48 57.02% ATO98189.1 Select seq sp|Q3LZX5.1| RecName: Full=Non-structural protein 8; Short=ns8; AltName: Full=Accessory protein 8; Flags: Precursor [Bat SARS coronavirus HKU3] 160 160 100% 2e-48 57.02% Q3LZX5.1 Select seq gb|ATO98227.1| ORF8 [Bat SARS-like coronavirus] 160 160 100% 2e-48 57.02% ATO98227.1

Wuhan seafood market pneumonia virus isolate Wuhan-Hu-1, complete genome GenBank: MN908947.1 FASTA Graphics Go to: LOCUS MN908947 30473 bp ss-RNA linear VRL 12-JAN-2020 DEFINITION Wuhan seafood market pneumonia virus isolate Wuhan-Hu-1, complete genome. ACCESSION MN908947 VERSION MN908947.1 KEYWORDS . SOURCE Wuhan seafood market pneumonia virus ORGANISM Wuhan seafood market pneumonia virus Viruses; Riboviria; Nidovirales; Cornidovirineae; Coronaviridae; Orthocoronavirinae; Betacoronavirus; unclassified Betacoronavirus. REFERENCE 1 (bases 1 to 30473) AUTHORS Zhang,Y.-Z., Wu,F., Chen,Y.-M., Pei,Y.-Y., Xu,L., Wang,W., Zhao,S., Yu,B., Hu,Y., Tao,Z.-W., Song,Z.-G., Tian,J.-H., Zhang,Y.-L., Liu,Y., Zheng,J.-J., Dai,F.-H., Wang,Q.-M., She,J.-L. and Zhu,T.-Y. TITLE A novel coronavirus associated with a respiratory disease in Wuhan of Hubei province, China JOURNAL Unpublished REFERENCE 2 (bases 1 to 30473) AUTHORS Zhang,Y.-Z., Wu,F., Chen,Y.-M., Pei,Y.-Y., Xu,L., Wang,W., Zhao,S., Yu,B., Hu,Y., Tao,Z.-W., Song,Z.-G., Tian,J.-H., Zhang,Y.-L., Liu,Y., Zheng,J.-J., Dai,F.-H., Wang,Q.-M., She,J.-L. and Zhu,T.-Y. TITLE Direct Submission JOURNAL Submitted (05-JAN-2020) Department of Zoonoses, National Institute of Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Changping Liuzi 5, Beijing 102206, China COMMENT ##Assembly-Data-START## Assembly Method :: Megahit v. V1.1.3 Sequencing Technology :: Illumina ##Assembly-Data-END## FEATURES Location/Qualifiers source 1..30473 /organism="Wuhan seafood market pneumonia virus" /mol_type="genomic RNA" /isolate="Wuhan-Hu-1" /host="Homo sapiens" /db_xref="taxon:2697049" /country="China" /collection_date="Dec-2019" 5'UTR 1..281 gene 282..21571 /gene="orf1ab" CDS join(282..13484,13484..21571) /gene="orf1ab" /ribosomal_slippage /note="pp1ab; translated by -1 ribosomal frameshift" /codon_start=1 /product="ORF1ab polyprotein" /protein_id="QHD43415.1" /translation="MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQ HLKDGTCGLVEVEKGVLPQLEQPYVFIKRSDARTAPHGHVMVELVAELEGIQYGRSGE TLGVLVPHVGEIPVAYRKVLLRKNGNKGAGGHSYGADLKSFDLGDELGTDPYEDFQEN WNTKHSSGVTRELMRELNGGAYTRYVDNNFCGPDGYPLECIKDLLARAGKASCTLSEQ LDFIDTKRGVYCCREHEHEIAWYTERSEKSYELQTPFEIKLAKKFDTFNGECPNFVFP LNSIIKTIQPRVEKKKLDGFMGRIRSVYPVASPNECNQMCLSTLMKCDHCGETSWQTG DFVKATCEFCGTENLTKEGATTCGYLPQNAVVKIYCPACHNSEVGPEHSLAEYHNESG LKTILRKGGRTIAFGGCVFSYVGCHNKCAYWVPRASANIGCNHTGVVGEGSEGLNDNL LEILQKEKVNINIVGDFKLNEEIAIILASFSASTSAFVETVKGLDYKAFKQIVESCGN FKVTKGKAKKGAWNIGEQKSILSPLYAFASEAARVVRSIFSRTLETAQNSVRVLQKAA ITILDGISQYSLRLIDAMMFTSDLATNNLVVMAYITGGVVQLTSQWLTNIFGTVYEKL KPVLDWLEEKFKEGVEFLRDGWEIVKFISTCACEIVGGQIVTCAKEIKESVQTFFKLV NKFLALCADSIIIGGAKLKALNLGETFVTHSKGLYRKCVKSREETGLLMPLKAPKEII FLEGETLPTEVLTEEVVLKTGDLQPLEQPTSEAVEAPLVGTPVCINGLMLLEIKDTEK YCALAPNMMVTNNTFTLKGGAPTKVTFGDDTVIEVQGYKSVNITFELDERIDKVLNEK CSAYTVELGTEVNEFACVVADAVIKTLQPVSELLTPLGIDLDEWSMATYYLFDESGEF KLASHMYCSFYPPDEDEEEGDCEEEEFEPSTQYEYGTEDDYQGKPLEFGATSAALQPE EEQEEDWLDDDSQQTVGQQDGSEDNQTTTIQTIVEVQPQLEMELTPVVQTIEVNSFSG YLKLTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESD DYIATNGPLKVGGSCVLSGHNLAKHCLHVVGPNVNKGEDIQLLKSAYENFNQHEVLLA PLLSAGIFGADPIHSLRVCVDTVRTNVYLAVFDKNLYDKLVSSFLEMKSEKQVEQKIA EIPKEEVKPFITESKPSVEQRKQDDKKIKACVEEVTTTLEETKFLTENLLLYIDINGN LHPDSATLVSDIDITFLKKDAPYIVGDVVQEGVLTAVVIPTKKAGGTTEMLAKALRKV PTDNYITTYPGQGLNGYTVEEAKTVLKKCKSAFYILPSIISNEKQEILGTVSWNLREM LAHAEETRKLMPVCVETKAIVSTIQRKYKGIKIQEGVVDYGARFYFYTSKTTVASLIN TLNDLNETLVTMPLGYVTHGLNLEEAARYMRSLKVPATVSVSSPDAVTAYNGYLTSSS KTPEEHFIETISLAGSYKDWSYSGQSTQLGIEFLKRGDKSVYYTSNPTTFHLDGEVIT FDNLKTLLSLREVRTIKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPH NSHEGKTFYVLPNDDTLRVEAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTSIK WADNNCYLATALLTLQQIELKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELG DVRETMSYLFQHANLDSCKRVLNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQ IPCTCGKQATKYLVQQESPFVMMSAPPAQYELKHGTFTCASEYTGNYQCGHYKHITSK ETLYCIDGALLTKSSEYKGPITDVFYKENSYTTTIKPVTYKLDGVVCTEIDPKLDNYY KKDNSYFTEQPIDLVPNQPYPNASFDNFKFVCDNIKFADDLNQLTGYKKPASRELKVT FFPDLNGDVVAIDYKHYTPSFKKGAKLLHKPIVWHVNNATNKATYKPNTWCIRCLWST KPVETSNSFDVLKSEDAQGMDNLACEDLKPVSEEVVENPTIQKDVLECNVKTTEVVGD IILKPANNSLKITEEVGHTDLMAAYVDNSSLTIKKPNELSRVLGLKTLATHGLAAVNS VPWDTIANYAKPFLNKVVSTTTNIVTRCLNRVCTNYMPYFFTLLLQLCTFTRSTNSRI KASMPTTIAKNTVKSVGKFCLEASFNYLKSPNFSKLINIIIWFLLLSVCLGSLIYSTA ALGVLMSNLGMPSYCTGYREGYLNSTNVTIATYCTGSIPCSVCLSGLDSLDTYPSLET IQITISSFKWDLTAFGLVAEWFLAYILFTRFFYVLGLAAIMQLFFSYFAVHFISNSWL MWLIINLVQMAPISAMVRMYIFFASFYYVWKSYVHVVDGCNSSTCMMCYKRNRATRVE CTTIVNGVRRSFYVYANGGKGFCKLHNWNCVNCDTFCAGSTFISDEVARDLSLQFKRP INPTDQSSYIVDSVTVKNGSIHLYFDKAGQKTYERHSLSHFVNLDNLRANNTKGSLPI NVIVFDGKSKCEESSAKSASVYYSQLMCQPILLLDQALVSDVGDSAEVAVKMFDAYVN TFSSTFNVPMEKLKTLVATAEAELAKNVSLDNVLSTFISAARQGFVDSDVETKDVVEC LKLSHQSDIEVTGDSCNNYMLTYNKVENMTPRDLGACIDCSARHINAQVAKSHNIALI WNVKDFMSLSEQLRKQIRSAAKKNNLPFKLTCATTRQVVNVVTTKIALKGGKIVNNWL KQLIKVTLVFLFVAAIFYLITPVHVMSKHTDFSSEIIGYKAIDGGVTRDIASTDTCFA NKHADFDTWFSQRGGSYTNDKACPLIAAVITREVGFVVPGLPGTILRTTNGDFLHFLP RVFSAVGNICYTPSKLIEYTDFATSACVLAAECTIFKDASGKPVPYCYDTNVLEGSVA YESLRPDTRYVLMDGSIIQFPNTYLEGSVRVVTTFDSEYCRHGTCERSEAGVCVSTSG RWVLNNDYYRSLPGVFCGVDAVNLLTNMFTPLIQPIGALDISASIVAGGIVAIVVTCL AYYFMRFRRAFGEYSHVVAFNTLLFLMSFTVLCLTPVYSFLPGVYSVIYLYLTFYLTN DVSFLAHIQWMVMFTPLVPFWITIAYIICISTKHFYWFFSNYLKRRVVFNGVSFSTFE EAALCTFLLNKEMYLKLRSDVLLPLTQYNRYLALYNKYKYFSGAMDTTSYREAACCHL AKALNDFSNSGSDVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNG LWLDDVVYCPRHVICTSEDMLNPNYEDLLIRKSNHNFLVQAGNVQLRVIGHSMQNCVL KLKVDTANPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNFTIKGSFLNGSC GSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGNFYGPFVDRQTAQAAGTDTTITVN VLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAV LDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQCSGVTFQSAVKRTIKGTHHW LLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFVKHKHAFLCLFL LPSLATVAYFNMVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASAVVLLILMTAR TVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGVVTTVMFLAR GIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTLGVYDYL VSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQSKMSDVKCTSVVL LSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVDINKL CEEMLDNRATLQAIASEFSSLPSYAAFATAQEAYEQAVANGDSEVVLKKLKKSLNVAK SEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALN NIINNARDGCVPLNIIPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDA DSKIVQLSEISMDNSPNLAWPLIVTALRANSAVKLQNNELSPVALRQMSCAAGTTQTA CTDDNALAYYNTTKGGRFVLALLSDLQDLKWARFPKSDGTGTIYTELEPPCRFVTDTP KGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDAAK AYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDH PNPKGFCDLKGKYVQIPTTCANDPVGFTLKNTVCTVCGMWKGYGCSCDQLREPMLQSA DAQSFLNRVCGVSAARLTPCGTGTSTDVVYRAFDIYNDKVAGFAKFLKTNCCRFQEKD EDDNLIDSYFVVKRHTFSNYQHEETIYNLLKDCPAVAKHDFFKFRIDGDMVPHISRQR LTKYTMADLVYALRHFDEGNCDTLKEILVTYNCCDDDYFNKKDWYDFVENPDILRVYA NLGERVRQALLKTVQFCDAMRNAGIVGVLTLDNQDLNGNWYDFGDFIQTTPGSGVPVV DSYYSLLMPILTLTRALTAESHVDTDLTKPYIKWDLLKYDFTEERLKLFDRYFKYWDQ TYHPNCVNCLDDRCILHCANFNVLFSTVFPPTSFGPLVRKIFVDGVPFVVSTGYHFRE LGVVHNQDVNLHSSRLSFKELLVYAADPAMHAASGNLLLDKRTTCFSVAALTNNVAFQ TVKPGNFNKDFYDFAVSKGFFKEGSSVELKHFFFAQDGNAAISDYDYYRYNLPTMCDI RQLLFVVEVVDKYFDCYDGGCINANQVIVNNLDKSAGFPFNKWGKARLYYDSMSYEDQ DALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICSTMTNRQFHQKLLKSIAAT RGATVVIGTSKFYGGWHNMLKTVYSDVENPHLMGWDYPKCDRAMPNMLRIMASLVLAR KHTTCCSLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNICQ AVTANVNALLSTDGNKIADKYVRNLQHRLYECLYRNRDVDTDFVNEFYAYLRKHFSMM ILSDDAVVCFNSTYASQGLVASIKNFKSVLYYQNNVFMSEAKCWTETDLTKGPHEFCS QHTMLVKQGDDYVYLPYPDPSRILGAGCFVDDIVKTDGTLMIERFVSLAIDAYPLTKH PNQEYADVFHLYLQYIRKLHDELTGHMLDMYSVMLTNDNTSRYWEPEFYEAMYTPHTV LQAVGACVLCNSQTSLRCGACIRRPFLCCKCCYDHVISTSHKLVLSVNPYVCNAPGCD VTDVTQLYLGGMSYYCKSHKPPISFPLCANGQVFGLYKNTCVGSDNVTDFNAIATCDW TNAGDYILANTCTERLKLFAAETLKATEETFKLSYGIATVREVLSDRELHLSWEVGKP RPPLNRNYVFTGYRVTKNSKVQIGEYTFEKGDYGDAVVYRGTTTYKLNVGDYFVLTSH TVMPLSAPTLVPQEHYVRITGLYPTLNISDEFSSNVANYQKVGMQKYSTLQGPPGTGK SHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARARVECFDKF KVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQ LPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLK AHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPYNSQNA VASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRAKVGILCIMSD RDLYDKLQFTSLEIPRRNVATLQAENVTGLFKDCSKVITGLHPTQAPTHLSVDTKFKT EGLCVDIPGIPKDMTYRRLISMMGFKMNYQVNGYPNMFITREEAIRHVRAWIGFDVEG CHATREAVGTNLPLQLGFSTGVNLVAVPTGYVDTPNNTDFSRVSAKPPPGDQFKHLIP LMYKGLPWNVVRIKIVQMLSDTLKNLSDRVVFVLWAHGFELTSMKYFVKIGPERTCCL CDRRATCFSTASDTYACWHHSIGFDYVYNPFMIDVQQWGFTGNLQSNHDLYCQVHGNA HVASCDAIMTRCLAVHECFVKRVDWTIEYPIIGDELKINAACRKVQHMVVKAALLADK FPVLHDIGNPKAIKCVPQADVEWKFYDAQPCSDKAYKIEELFYSYATHSDKFTDGVCL FWNCNVDRYPANSIVCRFDTRVLSNLNLPGCDGGSLYVNKHAFHTPAFDKSAFVNLKQ LPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLGGAVCRHHANEYRLYLDAYN MMISAGFSLWVYKQFDTYNLWNTFTRLQSLENVAFNVVNKGHFDGQQGEVPVSIINNT VYTKVDGVDVELFENKTTLPVNVAFELWAKRNIKPVPEVKILNNLGVDIAANTVIWDY KRDAPAHISTIGVCSMTDIAKKPTETICAPLTVFFDGRVDGQVDLFRNARNGVLITEG SVKGLQPSVGPKQASLNGVTLIGEAVKTQFNYYKKVDGVVQQLPETYFTQSRNLQEFK PRSQMEIDFLELAMDEFIERYKLEGYAFEHIVYGDFSHSQLGGLHLLIGLAKRFKESP FELEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSVVSKVVKV TIDYTEISFMLWCKDGHVETFYPKLQSSQAWQPGVAMPNLYKMQRMLLEKCDLQNYGD SATLPKGIMMNVAKYTQLCQYLNTLTLAVPYNMRVIHFGAGSDKGVAPGTAVLRQWLP TGTLLVDSDLNDFVSDADSTLIGDCATVHTANKWDLIISDMYDPKTKNVTKENDSKEG FFTYICGFIQQKLALGGSVAIKITEHSWNADLYKLMGHFAWWTAFVTNVNASSSEAFL IGCNYLGKPREQIDGYVMHANYIFWRNTNPIQLSSYSLFDMSKFPLKLRGTAVMSLKE GQINDMILSLLSKGRLIIRENNRVVISSDVLVNN" gene 21579..25400 /gene="S" CDS 21579..25400 /gene="S" /note="structural protein" /codon_start=1 /product="surface glycoprotein" /protein_id="QHD43416.1" /translation="MFVFLVLLPLVSSQCVNLTTRTQLPPAYTNSFTRGVYYPDKVFR SSVLHSTQDLFLPFFSNVTWFHAIHVSGTNGTKRFDNPVLPFNDGVYFASTEKSNIIR GWIFGTTLDSKTQSLLIVNNATNVVIKVCEFQFCNDPFLGVYYHKNNKSWMESEFRVY SSANNCTFEYVSQPFLMDLEGKQGNFKNLREFVFKNIDGYFKIYSKHTPINLVRDLPQ GFSALEPLVDLPIGINITRFQTLLALHRSYLTPGDSSSGWTAGAAAYYVGYLQPRTFL LKYNENGTITDAVDCALDPLSETKCTLKSFTVEKGIYQTSNFRVQPTESIVRFPNITN LCPFGEVFNATRFASVYAWNRKRISNCVADYSVLYNSASFSTFKCYGVSPTKLNDLCF TNVYADSFVIRGDEVRQIAPGQTGKIADYNYKLPDDFTGCVIAWNSNNLDSKVGGNYN YLYRLFRKSNLKPFERDISTEIYQAGSTPCNGVEGFNCYFPLQSYGFQPTNGVGYQPY RVVVLSFELLHAPATVCGPKKSTNLVKNKCVNFNFNGLTGTGVLTESNKKFLPFQQFG RDIADTTDAVRDPQTLEILDITPCSFGGVSVITPGTNTSNQVAVLYQDVNCTEVPVAI HADQLTPTWRVYSTGSNVFQTRAGCLIGAEHVNNSYECDIPIGAGICASYQTQTNSPR RARSVASQSIIAYTMSLGAENSVAYSNNSIAIPTNFTISVTTEILPVSMTKTSVDCTM YICGDSTECSNLLLQYGSFCTQLNRALTGIAVEQDKNTQEVFAQVKQIYKTPPIKDFG GFNFSQILPDPSKPSKRSFIEDLLFNKVTLADAGFIKQYGDCLGDIAARDLICAQKFN GLTVLPPLLTDEMIAQYTSALLAGTITSGWTFGAGAALQIPFAMQMAYRFNGIGVTQN VLYENQKLIANQFNSAIGKIQDSLSSTASALGKLQDVVNQNAQALNTLVKQLSSNFGA ISSVLNDILSRLDKVEAEVQIDRLITGRLQSLQTYVTQQLIRAAEIRASANLAATKMS ECVLGQSKRVDFCGKGYHLMSFPQSAPHGVVFLHVTYVPAQEKNFTTAPAICHDGKAH FPREGVFVSNGTHWFVTQRNFYEPQIITTDNTFVSGNCDVVIGIVNNTVYDPLQPELD SFKEELDKYFKNHTSPDVDLGDISGINASVVNIQKEIDRLNEVAKNLNESLIDLQELG KYEQYIKWPWYIWLGFIAGLIAIVMVTIMLCCMTSCCSCLKGCCSCGSCCKFDEDDSE PVLKGVKLHYT" gene 25409..26236 /gene="ORF3" CDS 25409..26236 /gene="ORF3" /codon_start=1 /product="ORF3 protein" /protein_id="QHD43417.1" /translation="MDLFMRIFTIGTVTLKQGEIKDATPSDFVRATATIPIQASLPFG WLIVGVALLAVFQSASKIITLKKRWQLALSKGVHFVCNLLLLFVTVYSHLLLVAAGLE APFLYLYALVYFLQSINFVRIIMRLWLCWKCRSKNPLLYDANYFLCWHTNCYDYCIPY NSVTSSIVITSGDGTTSPISEHDYQIGGYTEKWESGVKDCVVLHSYFTSDYYQLYSTQ LSTDTGVEHVTFFIYNKIVDEPEEHVQIHTIDGSSGVVNPVMEPIYDEPTTTTSVPL" gene 26261..26488 /gene="E" CDS 26261..26488 /gene="E" /note="structural protein; E protein" /codon_start=1 /product="envelope protein" /protein_id="QHD43418.1" /translation="MYSFVSEETGTLIVNSVLLFLAFVVFLLVTLAILTALRLCAYCC NIVNVSLVKPSFYVYSRVKNLNSSRVPDLLV" gene 26539..27207 /gene="M" CDS 26539..27207 /gene="M" /note="structural protein" /codon_start=1 /product="membrane glycoprotein" /protein_id="QHD43419.1" /translation="MADSNGTITVEELKKLLEQWNLVIGFLFLTWICLLQFAYANRNR FLYIIKLIFLWLLWPVTLACFVLAAVYRINWITGGIAIAMACLVGLMWLSYFIASFRL FARTRSMWSFNPETNILLNVPLHGTILTRPLLESELVIGAVILRGHLRIAGHHLGRCD IKDLPKEITVATSRTLSYYKLGASQRVAGDSGFAAYSRYRIGNYKLNTDHSSSSDNIA LLVQ" gene 27218..27403 /gene="ORF6" CDS 27218..27403 /gene="ORF6" /codon_start=1 /product="ORF6 protein" /protein_id="QHD43420.1" /translation="MFHLVDFQVTIAEILLIIMRTFKVSIWNLDYIINLIIKNLSKSL TENKYSQLDEEQPMEID" gene 27410..27775 /gene="ORF7" CDS 27410..27775 /gene="ORF7" /codon_start=1 /product="ORF7 protein" /protein_id="QHD43421.1" /translation="MKIILFLALITLATCELYHYQECVRGTTVLLKEPCSSGTYEGNS PFHPLADNKFALTCFSTQFAFACPDGVKHVYQLRARSVSPKLFIRQEEVQELYSPIFL IVAAIVFITLCFTLKRKTE" gene 27910..28275 /gene="ORF8" CDS 27910..28275 /gene="ORF8" /codon_start=1 /product="ORF8 protein" /protein_id="QHD43422.1" /translation="MKFLVFLGIITTVAAFHQECSLQSCTQHQPYVVDDPCPIHFYSK WYIRVGARKSAPLIELCVDEAGSKSPIQYIDIGNYTVSCLPFTINCQEPKLGSLVVRC SFYEDFLEYHDVRVVLDFI" gene 28290..29549 /gene="N" CDS 28290..29549 /gene="N" /note="structural protein" /codon_start=1 /product="nucleocapsid phosphoprotein" /protein_id="QHD43423.1" /translation="MSDNGPQNQRNAPRITFGGPSDSTGSNQNGERSGARSKQRRPQG LPNNTASWFTALTQHGKEDLKFPRGQGVPINTNSSPDDQIGYYRRATRRIRGGDGKMK DLSPRWYFYYLGTGPEAGLPYGANKDGIIWVATEGALNTPKDHIGTRNPANNAAIVLQ LPQGTTLPKGFYAEGSRGGSQASSRSSSRSRNSSRNSTPGSSRGTSPARMAGNGGDAA LALLLLDRLNQLESKMSGKGQQQQGQTVTKKSAAEASKKPRQKRTATKAYNVTQAFGR RGPEQTQGNFGDQELIRQGTDYKHWPQIAQFAPSASAFFGMSRIGMEVTPSGTWLTYT AAIKLDDKDPNFKDQVILLNKHIDAYKTFPPTEPKKDKKKKADETQALPQRQKKQQTV TLLPAADLDDFSKQLQQSMSSADSTQA" 3'UTR 29550..30473 ORIGIN 1 cggtgacgca tacaaaacat tcccaccata ccttcccagg taacaaacca accaactttc 61 gatctcttgt agatctgttc tctaaacgaa ctttaaaatc tgtgtggctg tcactcggct 121 gcatgcttag tgcactcacg cagtataatt aataactaat tactgtcgtt gacaggacac 181 gagtaactcg tctatcttct gcaggctgct tacggtttcg tccgtgttgc agccgatcat 241 cagcacatct aggtttcgtc cgggtgtgac cgaaaggtaa gatggagagc cttgtccctg 301 gtttcaacga gaaaacacac gtccaactca gtttgcctgt tttacaggtt cgcgacgtgc 361 tcgtacgtgg ctttggagac tccgtggagg aggtcttatc agaggcacgt caacatctta 421 aagatggcac ttgtggctta gtagaagttg aaaaaggcgt tttgcctcaa cttgaacagc 481 cctatgtgtt catcaaacgt tcggatgctc gaactgcacc tcatggtcat gttatggttg 541 agctggtagc agaactcgaa ggcattcagt acggtcgtag tggtgagaca cttggtgtcc 601 ttgtccctca tgtgggcgaa ataccagtgg cttaccgcaa ggttcttctt cgtaagaacg 661 gtaataaagg agctggtggc catagttacg gcgccgatct aaagtcattt gacttaggcg 721 acgagcttgg cactgatcct tatgaagatt ttcaagaaaa ctggaacact aaacatagca 781 gtggtgttac ccgtgaactc atgcgtgagc ttaacggagg ggcatacact cgctatgtcg 841 ataacaactt ctgtggccct gatggctacc ctcttgagtg cattaaagac cttctagcac 901 gtgctggtaa agcttcatgc actttgtccg aacaactgga ctttattgac actaagaggg 961 gtgtatactg ctgccgtgaa catgagcatg aaattgcttg gtacacggaa cgttctgaaa 1021 agagctatga attgcagaca ccttttgaaa ttaaattggc aaagaaattt gacaccttca 1081 atggggaatg tccaaatttt gtatttccct taaattccat aatcaagact attcaaccaa 1141 gggttgaaaa gaaaaagctt gatggcttta tgggtagaat tcgatctgtc tatccagttg 1201 cgtcaccaaa tgaatgcaac caaatgtgcc tttcaactct catgaagtgt gatcattgtg 1261 gtgaaacttc atggcagacg ggcgattttg ttaaagccac ttgcgaattt tgtggcactg 1321 agaatttgac taaagaaggt gccactactt gtggttactt accccaaaat gctgttgtta 1381 aaatttattg tccagcatgt cacaattcag aagtaggacc tgagcatagt cttgccgaat 1441 accataatga atctggcttg aaaaccattc ttcgtaaggg tggtcgcact attgcctttg 1501 gaggctgtgt gttctcttat gttggttgcc ataacaagtg tgcctattgg gttccacgtg 1561 ctagcgctaa cataggttgt aaccatacag gtgttgttgg agaaggttcc gaaggtctta 1621 atgacaacct tcttgaaata ctccaaaaag agaaagtcaa catcaatatt gttggtgact 1681 ttaaacttaa tgaagagatc gccattattt tggcatcttt ttctgcttcc acaagtgctt 1741 ttgtggaaac tgtgaaaggt ttggattata aagcattcaa acaaattgtt gaatcctgtg 1801 gtaattttaa agttacaaaa ggaaaagcta aaaaaggtgc ctggaatatt ggtgaacaga 1861 aatcaatact gagtcctctt tatgcatttg catcagaggc tgctcgtgtt gtacgatcaa 1921 ttttctcccg cactcttgaa actgctcaaa attctgtgcg tgttttacag aaggccgcta 1981 taacaatact agatggaatt tcacagtatt cactgagact cattgatgct atgatgttca 2041 catctgattt ggctactaac aatctagttg taatggccta cattacaggt ggtgttgttc 2101 agttgacttc gcagtggcta actaacatct ttggcactgt ttatgaaaaa ctcaaacccg 2161 tccttgattg gcttgaagag aagtttaagg aaggtgtaga gtttcttaga gacggttggg 2221 aaattgttaa atttatctca acctgtgctt gtgaaattgt cggtggacaa attgtcacct 2281 gtgcaaagga aattaaggag agtgttcaga cattctttaa gcttgtaaat aaatttttgg 2341 ctttgtgtgc tgactctatc attattggtg gagctaaact taaagccttg aatttaggtg 2401 aaacatttgt cacgcactca aagggattgt acagaaagtg tgttaaatcc agagaagaaa 2461 ctggcctact catgcctcta aaagccccaa aagaaattat cttcttagag ggagaaacac 2521 ttcccacaga agtgttaaca gaggaagttg tcttgaaaac tggtgattta caaccattag 2581 aacaacctac tagtgaagct gttgaagctc cattggttgg tacaccagtt tgtattaacg 2641 ggcttatgtt gctcgaaatc aaagacacag aaaagtactg tgcccttgca cctaatatga 2701 tggtaacaaa caataccttc acactcaaag gcggtgcacc aacaaaggtt acttttggtg 2761 atgacactgt gatagaagtg caaggttaca agagtgtgaa tatcactttt gaacttgatg 2821 aaaggattga taaagtactt aatgagaagt gctctgccta tacagttgaa ctcggtacag 2881 aagtaaatga gttcgcctgt gttgtggcag atgctgtcat aaaaactttg caaccagtat 2941 ctgaattact tacaccactg ggcattgatt tagatgagtg gagtatggct acatactact 3001 tatttgatga gtctggtgag tttaaattgg cttcacatat gtattgttct ttctaccctc 3061 cagatgagga tgaagaagaa ggtgattgtg aagaagaaga gtttgagcca tcaactcaat 3121 atgagtatgg tactgaagat gattaccaag gtaaaccttt ggaatttggt gccacttctg 3181 ctgctcttca acctgaagaa gagcaagaag aagattggtt agatgatgat agtcaacaaa 3241 ctgttggtca acaagacggc agtgaggaca atcagacaac tactattcaa acaattgttg 3301 aggttcaacc tcaattagag atggaactta caccagttgt tcagactatt gaagtgaata 3361 gttttagtgg ttatttaaaa cttactgaca atgtatacat taaaaatgca gacattgtgg 3421 aagaagctaa aaaggtaaaa ccaacagtgg ttgttaatgc agccaatgtt taccttaaac 3481 atggaggagg tgttgcagga gccttaaata aggctactaa caatgccatg caagttgaat 3541 ctgatgatta catagctact aatggaccac ttaaagtggg tggtagttgt gttttaagcg 3601 gacacaatct tgctaaacac tgtcttcatg ttgtcggccc aaatgttaac aaaggtgaag 3661 acattcaact tcttaagagt gcttatgaaa attttaatca gcacgaagtt ctacttgcac 3721 cattattatc agctggtatt tttggtgctg accctataca ttctttaaga gtttgtgtag 3781 atactgttcg cacaaatgtc tacttagctg tctttgataa aaatctctat gacaaacttg 3841 tttcaagctt tttggaaatg aagagtgaaa agcaagttga acaaaagatc gctgagattc 3901 ctaaagagga agttaagcca tttataactg aaagtaaacc ttcagttgaa cagagaaaac 3961 aagatgataa gaaaatcaaa gcttgtgttg aagaagttac aacaactctg gaagaaacta 4021 agttcctcac agaaaacttg ttactttata ttgacattaa tggcaatctt catccagatt 4081 ctgccactct tgttagtgac attgacatca ctttcttaaa gaaagatgct ccatatatag 4141 tgggtgatgt tgttcaagag ggtgttttaa ctgctgtggt tatacctact aaaaaggctg 4201 gtggcactac tgaaatgcta gcgaaagctt tgagaaaagt gccaacagac aattatataa 4261 ccacttaccc gggtcagggt ttaaatggtt acactgtaga ggaggcaaag acagtgctta 4321 aaaagtgtaa aagtgccttt tacattctac catctattat ctctaatgag aagcaagaaa 4381 ttcttggaac tgtttcttgg aatttgcgag aaatgcttgc acatgcagaa gaaacacgca 4441 aattaatgcc tgtctgtgtg gaaactaaag ccatagtttc aactatacag cgtaaatata 4501 agggtattaa aatacaagag ggtgtggttg attatggtgc tagattttac ttttacacca 4561 gtaaaacaac tgtagcgtca cttatcaaca cacttaacga tctaaatgaa actcttgtta 4621 caatgccact tggctatgta acacatggct taaatttgga agaagctgct cggtatatga 4681 gatctctcaa agtgccagct acagtttctg tttcttcacc tgatgctgtt acagcgtata 4741 atggttatct tacttcttct tctaaaacac ctgaagaaca ttttattgaa accatctcac 4801 ttgctggttc ctataaagat tggtcctatt ctggacaatc tacacaacta ggtatagaat 4861 ttcttaagag aggtgataaa agtgtatatt acactagtaa tcctaccaca ttccacctag 4921 atggtgaagt tatcaccttt gacaatctta agacacttct ttctttgaga gaagtgagga 4981 ctattaaggt gtttacaaca gtagacaaca ttaacctcca cacgcaagtt gtggacatgt 5041 caatgacata tggacaacag tttggtccaa cttatttgga tggagctgat gttactaaaa 5101 taaaacctca taattcacat gaaggtaaaa cattttatgt tttacctaat gatgacactc 5161 tacgtgttga ggcttttgag tactaccaca caactgatcc tagttttctg ggtaggtaca 5221 tgtcagcatt aaatcacact aaaaagtgga aatacccaca agttaatggt ttaacttcta 5281 ttaaatgggc agataacaac tgttatcttg ccactgcatt gttaacactc caacaaatag 5341 agttgaagtt taatccacct gctctacaag atgcttatta cagagcaagg gctggtgaag 5401 ctgctaactt ttgtgcactt atcttagcct actgtaataa gacagtaggt gagttaggtg 5461 atgttagaga aacaatgagt tacttgtttc aacatgccaa tttagattct tgcaaaagag 5521 tcttgaacgt ggtgtgtaaa acttgtggac aacagcagac aacccttaag ggtgtagaag 5581 ctgttatgta catgggcaca ctttcttatg aacaatttaa gaaaggtgtt cagatacctt 5641 gtacgtgtgg taaacaagct acaaaatatc tagtacaaca ggagtcacct tttgttatga 5701 tgtcagcacc acctgctcag tatgaactta agcatggtac atttacttgt gctagtgagt 5761 acactggtaa ttaccagtgt ggtcactata aacatataac ttctaaagaa actttgtatt 5821 gcatagacgg tgctttactt acaaagtcct cagaatacaa aggtcctatt acggatgttt 5881 tctacaaaga aaacagttac acaacaacca taaaaccagt tacttataaa ttggatggtg 5941 ttgtttgtac agaaattgac cctaagttgg acaattatta taagaaagac aattcttatt 6001 tcacagagca accaattgat cttgtaccaa accaaccata tccaaacgca agcttcgata 6061 attttaagtt tgtatgtgat aatatcaaat ttgctgatga tttaaaccag ttaactggtt 6121 ataagaaacc tgcttcaaga gagcttaaag ttacattttt ccctgactta aatggtgatg 6181 tggtggctat tgattataaa cactacacac cctcttttaa gaaaggagct aaattgttac 6241 ataaacctat tgtttggcat gttaacaatg caactaataa agccacgtat aaaccaaata 6301 cctggtgtat acgttgtctt tggagcacaa aaccagttga aacatcaaat tcgtttgatg 6361 tactgaagtc agaggacgcg cagggaatgg ataatcttgc ctgcgaagat ctaaaaccag 6421 tctctgaaga agtagtggaa aatcctacca tacagaaaga cgttcttgag tgtaatgtga 6481 aaactaccga agttgtagga gacattatac ttaaaccagc aaataatagt ttaaaaatta 6541 cagaagaggt tggccacaca gatctaatgg ctgcttatgt agacaattct agtcttacta 6601 ttaagaaacc taatgaatta tctagagtat taggtttgaa aacccttgct actcatggtt 6661 tagctgctgt taatagtgtc ccttgggata ctatagctaa ttatgctaag ccttttctta 6721 acaaagttgt tagtacaact actaacatag ttacacggtg tttaaaccgt gtttgtacta 6781 attatatgcc ttatttcttt actttattgc tacaattgtg tacttttact agaagtacaa 6841 attctagaat taaagcatct atgccgacta ctatagcaaa gaatactgtt aagagtgtcg 6901 gtaaattttg tctagaggct tcatttaatt atttgaagtc acctaatttt tctaaactga 6961 taaatattat aatttggttt ttactattaa gtgtttgcct aggttcttta atctactcaa 7021 ccgctgcttt aggtgtttta atgtctaatt taggcatgcc ttcttactgt actggttaca 7081 gagaaggcta tttgaactct actaatgtca ctattgcaac ctactgtact ggttctatac 7141 cttgtagtgt ttgtcttagt ggtttagatt ctttagacac ctatccttct ttagaaacta 7201 tacaaattac catttcatct tttaaatggg atttaactgc ttttggctta gttgcagagt 7261 ggtttttggc atatattctt ttcactaggt ttttctatgt acttggattg gctgcaatca 7321 tgcaattgtt tttcagctat tttgcagtac attttattag taattcttgg cttatgtggt 7381 taataattaa tcttgtacaa atggccccga tttcagctat ggttagaatg tacatcttct 7441 ttgcatcatt ttattatgta tggaaaagtt atgtgcatgt tgtagacggt tgtaattcat 7501 caacttgtat gatgtgttac aaacgtaata gagcaacaag agtcgaatgt acaactattg 7561 ttaatggtgt tagaaggtcc ttttatgtct atgctaatgg aggtaaaggc ttttgcaaac 7621 tacacaattg gaattgtgtt aattgtgata cattctgtgc tggtagtaca tttattagtg 7681 atgaagttgc gagagacttg tcactacagt ttaaaagacc aataaatcct actgaccagt 7741 cttcttacat cgttgatagt gttacagtga agaatggttc catccatctt tactttgata 7801 aagctggtca aaagacttat gaaagacatt ctctctctca ttttgttaac ttagacaacc 7861 tgagagctaa taacactaaa ggttcattgc ctattaatgt tatagttttt gatggtaaat 7921 caaaatgtga agaatcatct gcaaaatcag cgtctgttta ctacagtcag cttatgtgtc 7981 aacctatact gttactagat caggcattag tgtctgatgt tggtgatagt gcggaagttg 8041 cagttaaaat gtttgatgct tacgttaata cgttttcatc aacttttaac gtaccaatgg 8101 aaaaactcaa aacactagtt gcaactgcag aagctgaact tgcaaagaat gtgtccttag 8161 acaatgtctt atctactttt atttcagcag ctcggcaagg gtttgttgat tcagatgtag 8221 aaactaaaga tgttgttgaa tgtcttaaat tgtcacatca atctgacata gaagttactg 8281 gcgatagttg taataactat atgctcacct ataacaaagt tgaaaacatg acaccccgtg 8341 accttggtgc ttgtattgac tgtagtgcgc gtcatattaa tgcgcaggta gcaaaaagtc 8401 acaacattgc tttgatatgg aacgttaaag atttcatgtc attgtctgaa caactacgaa 8461 aacaaatacg tagtgctgct aaaaagaata acttaccttt taagttgaca tgtgcaacta 8521 ctagacaagt tgttaatgtt gtaacaacaa agatagcact taagggtggt aaaattgtta 8581 ataattggtt gaagcagtta attaaagtta cacttgtgtt cctttttgtt gctgctattt 8641 tctatttaat aacacctgtt catgtcatgt ctaaacatac tgacttttca agtgaaatca 8701 taggatacaa ggctattgat ggtggtgtca ctcgtgacat agcatctaca gatacttgtt 8761 ttgctaacaa acatgctgat tttgacacat ggtttagcca gcgtggtggt agttatacta 8821 atgacaaagc ttgcccattg attgctgcag tcataacaag agaagtgggt tttgtcgtgc 8881 ctggtttgcc tggcacgata ttacgcacaa ctaatggtga ctttttgcat ttcttaccta 8941 gagtttttag tgcagttggt aacatctgtt acacaccatc aaaacttata gagtacactg 9001 actttgcaac atcagcttgt gttttggctg ctgaatgtac aatttttaaa gatgcttctg 9061 gtaagccagt accatattgt tatgatacca atgtactaga aggttctgtt gcttatgaaa 9121 gtttacgccc tgacacacgt tatgtgctca tggatggctc tattattcaa tttcctaaca 9181 cctaccttga aggttctgtt agagtggtaa caacttttga ttctgagtac tgtaggcacg 9241 gcacttgtga aagatcagaa gctggtgttt gtgtatctac tagtggtaga tgggtactta 9301 acaatgatta ttacagatct ttaccaggag ttttctgtgg tgtagatgct gtaaatttac 9361 ttactaatat gtttacacca ctaattcaac ctattggtgc tttggacata tcagcatcta 9421 tagtagctgg tggtattgta gctatcgtag taacatgcct tgcctactat tttatgaggt 9481 ttagaagagc ttttggtgaa tacagtcatg tagttgcctt taatacttta ctattcctta 9541 tgtcattcac tgtactctgt ttaacaccag tttactcatt cttacctggt gtttattctg 9601 ttatttactt gtacttgaca ttttatctta ctaatgatgt ttctttttta gcacatattc 9661 agtggatggt tatgttcaca cctttagtac ctttctggat aacaattgct tatatcattt 9721 gtatttccac aaagcatttc tattggttct ttagtaatta cctaaagaga cgtgtagtct 9781 ttaatggtgt ttcctttagt acttttgaag aagctgcgct gtgcaccttt ttgttaaata 9841 aagaaatgta tctaaagttg cgtagtgatg tgctattacc tcttacgcaa tataatagat 9901 acttagctct ttataataag tacaagtatt ttagtggagc aatggataca actagctaca 9961 gagaagctgc ttgttgtcat ctcgcaaagg ctctcaatga cttcagtaac tcaggttctg 10021 atgttcttta ccaaccacca caaacctcta tcacctcagc tgttttgcag agtggtttta 10081 gaaaaatggc attcccatct ggtaaagttg agggttgtat ggtacaagta acttgtggta 10141 caactacact taacggtctt tggcttgatg acgtagttta ctgtccaaga catgtgatct 10201 gcacctctga agacatgctt aaccctaatt atgaagattt actcattcgt aagtctaatc 10261 ataatttctt ggtacaggct ggtaatgttc aactcagggt tattggacat tctatgcaaa 10321 attgtgtact taagcttaag gttgatacag ccaatcctaa gacacctaag tataagtttg 10381 ttcgcattca accaggacag actttttcag tgttagcttg ttacaatggt tcaccatctg 10441 gtgtttacca atgtgctatg aggcccaatt tcactattaa gggttcattc cttaatggtt 10501 catgtggtag tgttggtttt aacatagatt atgactgtgt ctctttttgt tacatgcacc 10561 atatggaatt accaactgga gttcatgctg gcacagactt agaaggtaac ttttatggac 10621 cttttgttga caggcaaaca gcacaagcag ctggtacgga cacaactatt acagttaatg 10681 ttttagcttg gttgtacgct gctgttataa atggagacag gtggtttctc aatcgattta 10741 ccacaactct taatgacttt aaccttgtgg ctatgaagta caattatgaa cctctaacac 10801 aagaccatgt tgacatacta ggacctcttt ctgctcaaac tggaattgcc gttttagata 10861 tgtgtgcttc attaaaagaa ttactgcaaa atggtatgaa tggacgtacc atattgggta 10921 gtgctttatt agaagatgaa tttacacctt ttgatgttgt tagacaatgc tcaggtgtta 10981 ctttccaaag tgcagtgaaa agaacaatca agggtacaca ccactggttg ttactcacaa 11041 ttttgacttc acttttagtt ttagtccaga gtactcaatg gtctttgttc ttttttttgt 11101 atgaaaatgc ctttttacct tttgctatgg gtattattgc tatgtctgct tttgcaatga 11161 tgtttgtcaa acataagcat gcatttctct gtttgttttt gttaccttct cttgccactg 11221 tagcttattt taatatggtc tatatgcctg ctagttgggt gatgcgtatt atgacatggt 11281 tggatatggt tgatactagt ttgtctggtt ttaagctaaa agactgtgtt atgtatgcat 11341 cagctgtagt gttactaatc cttatgacag caagaactgt gtatgatgat ggtgctagga 11401 gagtgtggac acttatgaat gtcttgacac tcgtttataa agtttattat ggtaatgctt 11461 tagatcaagc catttccatg tgggctctta taatctctgt tacttctaac tactcaggtg 11521 tagttacaac tgtcatgttt ttggccagag gtattgtttt tatgtgtgtt gagtattgcc 11581 ctattttctt cataactggt aatacacttc agtgtataat gctagtttat tgtttcttag 11641 gctatttttg tacttgttac tttggcctct tttgtttact caaccgctac tttagactga 11701 ctcttggtgt ttatgattac ttagtttcta cacaggagtt tagatatatg aattcacagg 11761 gactactccc acccaagaat agcatagatg ccttcaaact caacattaaa ttgttgggtg 11821 ttggtggcaa accttgtatc aaagtagcca ctgtacagtc taaaatgtca gatgtaaagt 11881 gcacatcagt agtcttactc tcagttttgc aacaactcag agtagaatca tcatctaaat 11941 tgtgggctca atgtgtccag ttacacaatg acattctctt agctaaagat actactgaag 12001 cctttgaaaa aatggtttca ctactttctg ttttgctttc catgcagggt gctgtagaca 12061 taaacaagct ttgtgaagaa atgctggaca acagggcaac cttacaagct atagcctcag 12121 agtttagttc ccttccatca tatgcagctt ttgctactgc tcaagaagct tatgagcagg 12181 ctgttgctaa tggtgattct gaagttgttc ttaaaaagtt gaagaagtct ttgaatgtgg 12241 ctaaatctga atttgaccgt gatgcagcca tgcaacgtaa gttggaaaag atggctgatc 12301 aagctatgac ccaaatgtat aaacaggcta gatctgagga caagagggca aaagttacta 12361 gtgctatgca gacaatgctt ttcactatgc ttagaaagtt ggataatgat gcactcaaca 12421 acattatcaa caatgcaaga gatggttgtg ttcccttgaa cataatacct cttacaacag 12481 cagccaaact aatggttgtc ataccagact ataacacata taaaaatacg tgtgatggta 12541 caacatttac ttatgcatca gcattgtggg aaatccaaca ggttgtagat gcagatagta 12601 aaattgttca acttagtgaa attagtatgg acaattcacc taatttagca tggcctctta 12661 ttgtaacagc tttaagggcc aattctgctg tcaaattaca gaataatgag cttagtcctg 12721 ttgcactacg acagatgtct tgtgctgccg gtactacaca aactgcttgc actgatgaca 12781 atgcgttagc ttactacaac acaacaaagg gaggtaggtt tgtacttgca ctgttatccg 12841 atttacagga tttgaaatgg gctagattcc ctaagagtga tggaactggt actatctata 12901 cagaactgga accaccttgt aggtttgtta cagacacacc taaaggtcct aaagtgaagt 12961 atttatactt tattaaagga ttaaacaacc taaatagagg tatggtactt ggtagtttag 13021 ctgccacagt acgtctacaa gctggtaatg caacagaagt gcctgccaat tcaactgtat 13081 tatctttctg tgcttttgct gtagatgctg ctaaagctta caaagattat ctagctagtg 13141 ggggacaacc aatcactaat tgtgttaaga tgttgtgtac acacactggt actggtcagg 13201 caataacagt tacaccggaa gccaatatgg atcaagaatc ctttggtggt gcatcgtgtt 13261 gtctgtactg ccgttgccac atagatcatc caaatcctaa aggattttgt gacttaaaag 13321 gtaagtatgt acaaatacct acaacttgtg ctaatgaccc tgtgggtttt acacttaaaa 13381 acacagtctg taccgtctgc ggtatgtgga aaggttatgg ctgtagttgt gatcaactcc 13441 gcgaacccat gcttcagtca gctgatgcac aatcgttttt aaacgggttt gcggtgtaag 13501 tgcagcccgt cttacaccgt gcggcacagg cactagtact gatgtcgtat acagggcttt 13561 tgacatctac aatgataaag tagctggttt tgctaaattc ctaaaaacta attgttgtcg 13621 cttccaagaa aaggacgaag atgacaattt aattgattct tactttgtag ttaagagaca 13681 cactttctct aactaccaac atgaagaaac aatttataat ttacttaagg attgtccagc 13741 tgttgctaaa catgacttct ttaagtttag aatagacggt gacatggtac cacatatatc 13801 acgtcaacgt cttactaaat acacaatggc agacctcgtc tatgctttaa ggcattttga 13861 tgaaggtaat tgtgacacat taaaagaaat acttgtcaca tacaattgtt gtgatgatga 13921 ttatttcaat aaaaaggact ggtatgattt tgtagaaaac ccagatatat tacgcgtata 13981 cgccaactta ggtgaacgtg tacgccaagc tttgttaaaa acagtacaat tctgtgatgc 14041 catgcgaaat gctggtattg ttggtgtact gacattagat aatcaagatc tcaatggtaa 14101 ctggtatgat ttcggtgatt tcatacaaac cacgccaggt agtggagttc ctgttgtaga 14161 ttcttattat tcattgttaa tgcctatatt aaccttgacc agggctttaa ctgcagagtc 14221 acatgttgac actgacttaa caaagcctta cattaagtgg gatttgttaa aatatgactt 14281 cacggaagag aggttaaaac tctttgaccg ttattttaaa tattgggatc agacatacca 14341 cccaaattgt gttaactgtt tggatgacag atgcattctg cattgtgcaa actttaatgt 14401 tttattctct acagtgttcc cacctacaag ttttggacca ctagtgagaa aaatatttgt 14461 tgatggtgtt ccatttgtag tttcaactgg ataccacttc agagagctag gtgttgtaca 14521 taatcaggat gtaaacttac atagctctag acttagtttt aaggaattac ttgtgtatgc 14581 tgctgaccct gctatgcacg ctgcttctgg taatctatta ctagataaac gcactacgtg 14641 cttttcagta gctgcactta ctaacaatgt tgcttttcaa actgtcaaac ccggtaattt 14701 taacaaagac ttctatgact ttgctgtgtc taagggtttc tttaaggaag gaagttctgt 14761 tgaattaaaa cacttcttct ttgctcagga tggtaatgct gctatcagcg attatgacta 14821 ctatcgttat aatctaccaa caatgtgtga tatcagacaa ctactatttg tagttgaagt 14881 tgttgataag tactttgatt gttacgatgg tggctgtatt aatgctaacc aagtcatcgt 14941 caacaaccta gacaaatcag ctggttttcc atttaataaa tggggtaagg ctagacttta 15001 ttatgattca atgagttatg aggatcaaga tgcacttttc gcatatacaa aacgtaatgt 15061 catccctact ataactcaaa tgaatcttaa gtatgccatt agtgcaaaga atagagctcg 15121 caccgtagct ggtgtctcta tctgtagtac tatgaccaat agacagtttc atcaaaaatt 15181 attgaaatca atagccgcca ctagaggagc tactgtagta attggaacaa gcaaattcta 15241 tggtggttgg cacaacatgt taaaaactgt ttatagtgat gtagaaaacc ctcaccttat 15301 gggttgggat tatcctaaat gtgatagagc catgcctaac atgcttagaa ttatggcctc 15361 acttgttctt gctcgcaaac atacaacgtg ttgtagcttg tcacaccgtt tctatagatt 15421 agctaatgag tgtgctcaag tattgagtga aatggtcatg tgtggcggtt cactatatgt 15481 taaaccaggt ggaacctcat caggagatgc cacaactgct tatgctaata gtgtttttaa 15541 catttgtcaa gctgtcacgg ccaatgttaa tgcactttta tctactgatg gtaacaaaat 15601 tgccgataag tatgtccgca atttacaaca cagactttat gagtgtctct atagaaatag 15661 agatgttgac acagactttg tgaatgagtt ttacgcatat ttgcgtaaac atttctcaat 15721 gatgatactc tctgacgatg ctgttgtgtg tttcaatagc acttatgcat ctcaaggtct 15781 agtggctagc ataaagaact ttaagtcagt tctttattat caaaacaatg tttttatgtc 15841 tgaagcaaaa tgttggactg agactgacct tactaaagga cctcatgaat tttgctctca 15901 acatacaatg ctagttaaac agggtgatga ttatgtgtac cttccttacc cagatccatc 15961 aagaatccta ggggccggct gttttgtaga tgatatcgta aaaacagatg gtacacttat 16021 gattgaacgg ttcgtgtctt tagctataga tgcttaccca cttactaaac atcctaatca 16081 ggagtatgct gatgtctttc atttgtactt acaatacata agaaagctac atgatgagtt 16141 aacaggacac atgttagaca tgtattctgt tatgcttact aatgataaca cttcaaggta 16201 ttgggaacct gagttttatg aggctatgta cacaccgcat acagtcttac aggctgttgg 16261 ggcttgtgtt ctttgcaatt cacagacttc attaagatgt ggtgcttgca tacgtagacc 16321 attcttatgt tgtaaatgct gttacgacca tgtcatatca acatcacata aattagtctt 16381 gtctgttaat ccgtatgttt gcaatgctcc aggttgtgat gtcacagatg tgactcaact 16441 ttacttagga ggtatgagct attattgtaa atcacataaa ccacccatta gttttccatt 16501 gtgtgctaat ggacaagttt ttggtttata taaaaataca tgtgttggta gcgataatgt 16561 tactgacttt aatgcaattg caacatgtga ctggacaaat gctggtgatt acattttagc 16621 taacacctgt actgaaagac tcaagctttt tgcagcagaa acgctcaaag ctactgagga 16681 gacatttaaa ctgtcttatg gtattgctac tgtacgtgaa gtgctgtctg acagagaatt 16741 acatctttca tgggaagttg gtaaacctag accaccactt aaccgaaatt atgtctttac 16801 tggttatcgt gtaactaaaa acagtaaagt acaaatagga gagtacacct ttgaaaaagg 16861 tgactatggt gatgctgttg tttaccgagg tacaacaact tacaaattaa atgttggtga 16921 ttattttgtg ctgacatcac atacagtaat gccattaagt gcacctacac tagtgccaca 16981 agagcactat gttagaatta ctggcttata cccaacactc aatatctcag atgagttttc 17041 tagcaatgtt gcaaattatc aaaaggttgg tatgcaaaag tattctacac tccagggacc 17101 acctggtact ggtaagagtc attttgctat tggcctagct ctctactacc cttctgctcg 17161 catagtgtat acagcttgct ctcatgccgc tgttgatgca ctatgtgaga aggcattaaa 17221 atatttgcct atagataaat gtagtagaat tatacctgca cgtgctcgtg tagagtgttt 17281 tgataaattc aaagtgaatt caacattaga acagtatgtc ttttgtactg taaatgcatt 17341 gcctgagacg acagcagata tagttgtctt tgatgaaatt tcaatggcca caaattatga 17401 tttgagtgtt gtcaatgcca gattacgtgc taagcactat gtgtacattg gcgaccctgc 17461 tcaattacct gcaccacgca cattgctaac taagggcaca ctagaaccag aatatttcaa 17521 ttcagtgtgt agacttatga aaactatagg tccagacatg ttcctcggaa cttgtcggcg 17581 ttgtcctgct gaaattgttg acactgtgag tgctttggtt tatgataata agcttaaagc 17641 acataaagac aaatcagctc aatgctttaa aatgttttat aagggtgtta tcacgcatga 17701 tgtttcatct gcaattaaca ggccacaaat aggcgtggta agagaattcc ttacacgtaa 17761 ccctgcttgg agaaaagctg tctttatttc accttataat tcacagaatg ctgtagcctc 17821 aaagattttg ggactaccaa ctcaaactgt tgattcatca cagggctcag aatatgacta 17881 tgtcatattc actcaaacca ctgaaacagc tcactcttgt aatgtaaaca gatttaatgt 17941 tgctattacc agagcaaaag taggcatact ttgcataatg tctgatagag acctttatga 18001 caagttgcaa tttacaagtc ttgaaattcc acgtaggaat gtggcaactt tacaagctga 18061 aaatgtaaca ggactcttta aagattgtag taaggtaatc actgggttac atcctacaca 18121 ggcacctaca cacctcagtg ttgacactaa attcaaaact gaaggtttat gtgttgacat 18181 acctggcata cctaaggaca tgacctatag aagactcatc tctatgatgg gttttaaaat 18241 gaattatcaa gttaatggtt accctaacat gtttatcacc cgcgaagaag ctataagaca 18301 tgtacgtgca tggattggct tcgatgtcga ggggtgtcat gctactagag aagctgttgg 18361 taccaattta cctttacagc taggtttttc tacaggtgtt aacctagttg ctgtacctac 18421 aggttatgtt gatacaccta ataatacaga tttttccaga gttagtgcta aaccaccgcc 18481 tggagatcaa tttaaacacc tcataccact tatgtacaaa ggacttcctt ggaatgtagt 18541 gcgtataaag attgtacaaa tgttaagtga cacacttaaa aatctctctg acagagtcgt 18601 atttgtctta tgggcacatg gctttgagtt gacatctatg aagtattttg tgaaaatagg 18661 acctgagcgc acctgttgtc tatgtgatag acgtgccaca tgcttttcca ctgcttcaga 18721 cacttatgcc tgttggcatc attctattgg atttgattac gtctataatc cgtttatgat 18781 tgatgttcaa caatggggtt ttacaggtaa cctacaaagc aaccatgatc tgtattgtca 18841 agtccatggt aatgcacatg tagctagttg tgatgcaatc atgactaggt gtctagctgt 18901 ccacgagtgc tttgttaagc gtgttgactg gactattgaa tatcctataa ttggtgatga 18961 actgaagatt aatgcggctt gtagaaaggt tcaacacatg gttgttaaag ctgcattatt 19021 agcagacaaa ttcccagttc ttcacgacat tggtaaccct aaagctatta agtgtgtacc 19081 tcaagctgat gtagaatgga agttctatga tgcacagcct tgtagtgaca aagcttataa 19141 aatagaagaa ttattctatt cttatgccac acattctgac aaattcacag atggtgtatg 19201 cctattttgg aattgcaatg tcgatagata tcctgctaat tccattgttt gtagatttga 19261 cactagagtg ctatctaacc ttaacttgcc tggttgtgat ggtggcagtt tgtatgtaaa 19321 taaacatgca ttccacacac cagcttttga taaaagtgct tttgttaatt taaaacaatt 19381 accatttttc tattactctg acagtccatg tgagtctcat ggaaaacaag tagtgtcaga 19441 tatagattat gtaccactaa agtctgctac gtgtataaca cgttgcaatt taggtggtgc 19501 tgtctgtaga catcatgcta atgagtacag attgtatctc gatgcttata acatgatgat 19561 ctcagctggc tttagcttgt gggtttacaa acaatttgat acttataacc tctggaacac 19621 ttttacaaga cttcagagtt tagaaaatgt ggcttttaat gttgtaaata agggacactt 19681 tgatggacaa cagggtgaag taccagtttc tatcattaat aacactgttt acacaaaagt 19741 tgatggtgtt gatgtagaat tgtttgaaaa taaaacaaca ttacctgtta atgtagcatt 19801 tgagctttgg gctaagcgca acattaaacc agtaccagag gtgaaaatac tcaataattt 19861 gggtgtggac attgctgcta atactgtgat ctgggactac aaaagagatg ctccagcaca 19921 tatatctact attggtgttt gttctatgac tgacatagcc aagaaaccaa ctgaaacgat 19981 ttgtgcacca ctcactgtct tttttgatgg tagagttgat ggtcaagtag acttatttag 20041 aaatgcccgt aatggtgttc ttattacaga aggtagtgtt aaaggtttac aaccatctgt 20101 aggtcccaaa caagctagtc ttaatggagt cacattaatt ggagaagccg taaaaacaca 20161 gttcaattat tataagaaag ttgatggtgt tgtccaacaa ttacctgaaa cttactttac 20221 tcagagtaga aatttacaag aatttaaacc caggagtcaa atggaaattg atttcttaga 20281 attagctatg gatgaattca ttgaacggta taaattagaa ggctatgcct tcgaacatat 20341 cgtttatgga gattttagtc atagtcagtt aggtggttta catctactga ttggactagc 20401 taaacgtttt aaggaatcac cttttgaatt agaagatttt attcctatgg acagtacagt 20461 taaaaactat ttcataacag atgcgcaaac aggttcatct aagtgtgtgt gttctgttat 20521 tgatttatta cttgatgatt ttgttgaaat aataaaatcc caagatttat ctgtagtttc 20581 taaggttgtc aaagtgacta ttgactatac agaaatttca tttatgcttt ggtgtaaaga 20641 tggccatgta gaaacatttt acccaaaatt acaatctagt caagcgtggc aaccgggtgt 20701 tgctatgcct aatctttaca aaatgcaaag aatgctatta gaaaagtgtg accttcaaaa 20761 ttatggtgat agtgcaacat tacctaaagg cataatgatg aatgtcgcaa aatatactca 20821 actgtgtcaa tatttaaaca cattaacatt agctgtaccc tataatatga gagttataca 20881 ttttggtgct ggttctgata aaggagttgc accaggtaca gctgttttaa gacagtggtt 20941 gcctacgggt acgctgcttg tcgattcaga tcttaatgac tttgtctctg atgcagattc 21001 aactttgatt ggtgattgtg caactgtaca tacagctaat aaatgggatc tcattattag 21061 tgatatgtac gaccctaaga ctaaaaatgt tacaaaagaa aatgactcta aagagggttt 21121 tttcacttac atttgtgggt ttatacaaca aaagctagct cttggaggtt ccgtggctat 21181 aaagataaca gaacattctt ggaatgctga tctttataag ctcatgggac acttcgcatg 21241 gtggacagcc tttgttacta atgtgaatgc gtcatcatct gaagcatttt taattggatg 21301 taattatctt ggcaaaccac gcgaacaaat agatggttat gtcatgcatg caaattacat 21361 attttggagg aatacaaatc caattcagtt gtcttcctat tctttatttg acatgagtaa 21421 atttcccctt aaattaaggg gtactgctgt tatgtcttta aaagaaggtc aaatcaatga 21481 tatgatttta tctcttctta gtaaaggtag acttataatt agagaaaaca acagagttgt 21541 tatttctagt gatgttcttg ttaacaacta aacgaacaat gtttgttttt cttgttttat 21601 tgccactagt ctctagtcag tgtgttaatc ttacaaccag aactcaatta ccccctgcat 21661 acactaattc tttcacacgt ggtgtttatt accctgacaa agttttcaga tcctcagttt 21721 tacattcaac tcaggacttg ttcttacctt tcttttccaa tgttacttgg ttccatgcta 21781 tacatgtctc tgggaccaat ggtactaaga ggtttgataa ccctgtccta ccatttaatg 21841 atggtgttta ttttgcttcc actgagaagt ctaacataat aagaggctgg atttttggta 21901 ctactttaga ttcgaagacc cagtccctac ttattgttaa taacgctact aatgttgtta 21961 ttaaagtctg tgaatttcaa ttttgtaatg atccattttt gggtgtttat taccacaaaa 22021 acaacaaaag ttggatggaa agtgagttca gagtttattc tagtgcgaat aattgcactt 22081 ttgaatatgt ctctcagcct tttcttatgg accttgaagg aaaacagggt aatttcaaaa 22141 atcttaggga atttgtgttt aagaatattg atggttattt taaaatatat tctaagcaca 22201 cgcctattaa tttagtgcgt gatctccctc agggtttttc ggctttagaa ccattggtag 22261 atttgccaat aggtattaac atcactaggt ttcaaacttt acttgcttta catagaagtt 22321 atttgactcc tggtgattct tcttcaggtt ggacagctgg tgctgcagct tattatgtgg 22381 gttatcttca acctaggact tttctattaa aatataatga aaatggaacc attacagatg 22441 ctgtagactg tgcacttgac cctctctcag aaacaaagtg tacgttgaaa tccttcactg 22501 tagaaaaagg aatctatcaa acttctaact ttagagtcca accaacagaa tctattgtta 22561 gatttcctaa tattacaaac ttgtgccctt ttggtgaagt ttttaacgcc accagatttg 22621 catctgttta tgcttggaac aggaagagaa tcagcaactg tgttgctgat tattctgtcc 22681 tatataattc cgcatcattt tccactttta agtgttatgg agtgtctcct actaaattaa 22741 atgatctctg ctttactaat gtctatgcag attcatttgt aattagaggt gatgaagtca 22801 gacaaatcgc tccagggcaa actggaaaga ttgctgatta taattataaa ttaccagatg 22861 attttacagg ctgcgttata gcttggaatt ctaacaatct tgattctaag gttggtggta 22921 attataatta cctgtataga ttgtttagga agtctaatct caaacctttt gagagagata 22981 tttcaactga aatctatcag gccggtagca caccttgtaa tggtgttgaa ggttttaatt 23041 gttactttcc tttacaatca tatggtttcc aacccactaa tggtgttggt taccaaccat 23101 acagagtagt agtactttct tttgaacttc tacatgcacc agcaactgtt tgtggaccta 23161 aaaagtctac taatttggtt aaaaacaaat gtgtcaattt caacttcaat ggtttaacag 23221 gcacaggtgt tcttactgag tctaacaaaa agtttctgcc tttccaacaa tttggcagag 23281 acattgctga cactactgat gctgtccgtg atccacagac acttgagatt cttgacatta 23341 caccatgttc ttttggtggt gtcagtgtta taacaccagg aacaaatact tctaaccagg 23401 ttgctgttct ttatcaggat gttaactgca cagaagtccc tgttgctatt catgcagatc 23461 aacttactcc tacttggcgt gtttattcta caggttctaa tgtttttcaa acacgtgcag 23521 gctgtttaat aggggctgaa catgtcaaca actcatatga gtgtgacata cccattggtg 23581 caggtatatg cgctagttat cagactcaga ctaattctcc tcggcgggca cgtagtgtag 23641 ctagtcaatc catcattgcc tacactatgt cacttggtgc agaaaattca gttgcttact 23701 ctaataactc tattgccata cccacaaatt ttactattag tgttaccaca gaaattctac 23761 cagtgtctat gaccaagaca tcagtagatt gtacaatgta catttgtggt gattcaactg 23821 aatgcagcaa tcttttgttg caatatggca gtttttgtac acaattaaac cgtgctttaa 23881 ctggaatagc tgttgaacaa gacaaaaaca cccaagaagt ttttgcacaa gtcaaacaaa 23941 tttacaaaac accaccaatt aaagattttg gtggttttaa tttttcacaa atattaccag 24001 atccatcaaa accaagcaag aggtcattta ttgaagatct acttttcaac aaagtgacac 24061 ttgcagatgc tggcttcatc aaacaatatg gtgattgcct tggtgatatt gctgctagag 24121 acctcatttg tgcacaaaag tttaacggcc ttactgtttt gccacctttg ctcacagatg 24181 aaatgattgc tcaatacact tctgcactgt tagcgggtac aatcacttct ggttggacct 24241 ttggtgcagg tgctgcatta caaataccat ttgctatgca aatggcttat aggtttaatg 24301 gtattggagt tacacagaat gttctctatg agaaccaaaa attgattgcc aaccaattta 24361 atagtgctat tggcaaaatt caagactcac tttcttccac agcaagtgca cttggaaaac 24421 ttcaagatgt ggtcaaccaa aatgcacaag ctttaaacac gcttgttaaa caacttagct 24481 ccaattttgg tgcaatttca agtgttttaa atgatatcct ttcacgtctt gacaaagttg 24541 aggctgaagt gcaaattgat aggttgatca caggcagact tcaaagtttg cagacatatg 24601 tgactcaaca attaattaga gctgcagaaa tcagagcttc tgctaatctt gctgctacta 24661 aaatgtcaga gtgtgtactt ggacaatcaa aaagagttga tttttgtgga aagggctatc 24721 atcttatgtc cttccctcag tcagcacctc atggtgtagt cttcttgcat gtgacttatg 24781 tccctgcaca agaaaagaac ttcacaactg ctcctgccat ttgtcatgat ggaaaagcac 24841 actttcctcg tgaaggtgtc tttgtttcaa atggcacaca ctggtttgta acacaaagga 24901 atttttatga accacaaatc attactacag acaacacatt tgtgtctggt aactgtgatg 24961 ttgtaatagg aattgtcaac aacacagttt atgatccttt gcaacctgaa ttagactcat 25021 tcaaggagga gttagataaa tattttaaga atcatacatc accagatgtt gatttaggtg 25081 acatctctgg cattaatgct tcagttgtaa acattcaaaa agaaattgac cgcctcaatg 25141 aggttgccaa gaatttaaat gaatctctca tcgatctcca agaacttgga aagtatgagc 25201 agtatataaa atggccatgg tacatttggc taggttttat agctggcttg attgccatag 25261 taatggtgac aattatgctt tgctgtatga ccagttgctg tagttgtctc aagggctgtt 25321 gttcttgtgg atcctgctgc aaatttgatg aagacgactc tgagccagtg ctcaaaggag 25381 tcaaattaca ttacacataa acgaacttat ggatttgttt atgagaatct tcacaattgg 25441 aactgtaact ttgaagcaag gtgaaatcaa ggatgctact ccttcagatt ttgttcgcgc 25501 tactgcaacg ataccgatac aagcctcact ccctttcgga tggcttattg ttggcgttgc 25561 acttcttgct gtttttcaga gcgcttccaa aatcataacc ctcaaaaaga gatggcaact 25621 agcactctcc aagggtgttc actttgtttg caacttgctg ttgttgtttg taacagttta 25681 ctcacacctt ttgctcgttg ctgctggcct tgaagcccct tttctctatc tttatgcttt 25741 agtctacttc ttgcagagta taaactttgt aagaataata atgaggcttt ggctttgctg 25801 gaaatgccgt tccaaaaacc cattacttta tgatgccaac tattttcttt gctggcatac 25861 taattgttac gactattgta taccttacaa tagtgtaact tcttcaattg tcattacttc 25921 aggtgatggc acaacaagtc ctatttctga acatgactac cagattggtg gttatactga 25981 aaaatgggaa tctggagtaa aagactgtgt tgtattacac agttacttca cttcagacta 26041 ttaccagctg tactcaactc aattgagtac agacactggt gttgaacatg ttaccttctt 26101 catctacaat aaaattgttg atgagcctga agaacatgtc caaattcaca caatcgacgg 26161 ttcatccgga gttgttaatc cagtaatgga accaatttat gatgaaccga cgacgactac 26221 tagcgtgcct ttgtaagcac aagctgatga gtacgaactt atgtactcat tcgtttcgga 26281 agagacaggt acgttaatag ttaatagcgt acttcttttt cttgctttcg tggtattctt 26341 gctagttaca ctagccatcc ttactgcgct tcgattgtgt gcgtactgct gcaatattgt 26401 taacgtgagt cttgtaaaac cttcttttta cgtttactct cgtgttaaaa atctgaattc 26461 ttctagagtt cctgatcttc tggtctaaac gaactaaata ttatattagt ttttctgttt 26521 ggaactttaa ttttagccat ggcagattcc aacggtacta ttaccgttga agagcttaaa 26581 aagctccttg aacaatggaa cctagtaata ggtttcctat tccttacatg gatttgtctt 26641 ctacaatttg cctatgccaa caggaatagg tttttgtata taattaagtt aattttcctc 26701 tggctgttat ggccagtaac tttagcttgt tttgtgcttg ctgctgttta cagaataaat 26761 tggatcaccg gtggaattgc tatcgcaatg gcttgtcttg taggcttgat gtggctcagc 26821 tacttcattg cttctttcag actgtttgcg cgtacgcgtt ccatgtggtc attcaatcca 26881 gaaactaaca ttcttctcaa cgtgccactc catggcacta ttctgaccag accgcttcta 26941 gaaagtgaac tcgtaatcgg agctgtgatc cttcgtggac atcttcgtat tgctggacac 27001 catctaggac gctgtgacat caaggacctg cctaaagaaa tcactgttgc tacatcacga 27061 acgctttctt attacaaatt gggagcttcg cagcgtgtag caggtgactc aggttttgct 27121 gcatacagtc gctacaggat tggcaactat aaattaaaca cagaccattc cagtagcagt 27181 gacaatattg ctttgcttgt acagtaagtg acaacagatg tttcatctcg ttgactttca 27241 ggttactata gcagagatat tactaattat tatgaggact tttaaagttt ccatttggaa 27301 tcttgattac atcataaacc tcataattaa aaatttatct aagtcactaa ctgagaataa 27361 atattctcaa ttagatgaag agcaaccaat ggagattgat taaacgaaca tgaaaattat 27421 tcttttcttg gcactgataa cactcgctac ttgtgagctt tatcactacc aagagtgtgt 27481 tagaggtaca acagtacttt taaaagaacc ttgctcttct ggaacatacg agggcaattc 27541 accatttcat cctctagctg ataacaaatt tgcactgact tgctttagca ctcaatttgc 27601 ttttgcttgt cctgacggcg taaaacacgt ctatcagtta cgtgccagat cagtttcacc 27661 taaactgttc atcagacaag aggaagttca agaactttac tctccaattt ttcttattgt 27721 tgcggcaata gtgtttataa cactttgctt cacactcaaa agaaagacag aatgattgaa 27781 ctttcattaa ttgacttcta tttgtgcttt ttagcctttc tgctattcct tgttttaatt 27841 atgcttatta tcttttggtt ctcacttgaa ctgcaagatc ataatgaaac ttgtcacgcc 27901 taaacgaaca tgaaatttct tgttttctta ggaatcatca caactgtagc tgcatttcac 27961 caagaatgta gtttacagtc atgtactcaa catcaaccat atgtagttga tgacccgtgt 28021 cctattcact tctattctaa atggtatatt agagtaggag ctagaaaatc agcaccttta 28081 attgaattgt gcgtggatga ggctggttct aaatcaccca ttcagtacat cgatatcggt 28141 aattatacag tttcctgttt accttttaca attaattgcc aggaacctaa attgggtagt 28201 cttgtagtgc gttgttcgtt ctatgaagac tttttagagt atcatgacgt tcgtgttgtt 28261 ttagatttca tctaaacgaa caaactaaaa tgtctgataa tggaccccaa aatcagcgaa 28321 atgcaccccg cattacgttt ggtggaccct cagattcaac tggcagtaac cagaatggag 28381 aacgcagtgg ggcgcgatca aaacaacgtc ggccccaagg tttacccaat aatactgcgt 28441 cttggttcac cgctctcact caacatggca aggaagacct taaattccct cgaggacaag 28501 gcgttccaat taacaccaat agcagtccag atgaccaaat tggctactac cgaagagcta 28561 ccagacgaat tcgtggtggt gacggtaaaa tgaaagatct cagtccaaga tggtatttct 28621 actacctagg aactgggcca gaagctggac ttccctatgg tgctaacaaa gacggcatca 28681 tatgggttgc aactgaggga gccttgaata caccaaaaga tcacattggc acccgcaatc 28741 ctgctaacaa tgctgcaatc gtgctacaac ttcctcaagg aacaacattg ccaaaaggct 28801 tctacgcaga agggagcaga ggcggcagtc aagcctcttc tcgttcctca tcacgtagtc 28861 gcaacagttc aagaaattca actccaggca gcagtagggg aacttctcct gctagaatgg 28921 ctggcaatgg cggtgatgct gctcttgctt tgctgctgct tgacagattg aaccagcttg 28981 agagcaaaat gtctggtaaa ggccaacaac aacaaggcca aactgtcact aagaaatctg 29041 ctgctgaggc ttctaagaag cctcggcaaa aacgtactgc cactaaagca tacaatgtaa 29101 cacaagcttt cggcagacgt ggtccagaac aaacccaagg aaattttggg gaccaggaac 29161 taatcagaca aggaactgat tacaaacatt ggccgcaaat tgcacaattt gcccccagcg 29221 cttcagcgtt cttcggaatg tcgcgcattg gcatggaagt cacaccttcg ggaacgtggt 29281 tgacctacac agctgccatc aaattggatg acaaagatcc aaatttcaaa gatcaagtca 29341 ttttgctgaa taagcatatt gacgcataca aaacattccc accaacagag cctaaaaagg 29401 acaaaaagaa gaaggctgat gaaactcaag ccttaccgca gagacagaag aaacagcaaa 29461 ctgtgactct tcttcctgct gcagatttgg atgatttctc caaacaattg caacaatcca 29521 tgagcagtgc tgactcaact caggcctaaa ctcatgcaga ccacacaagg cagatgggct 29581 atataaacgt tttcgctttt ccgtttacga tatatagtct actcttgtgc agaatgaatt 29641 ctcgtaacta catagcacaa gtagatgtag ttaactttaa tctcacatag caatctttaa 29701 tcagtgtgta acattaggga ggacttgaaa gagccaccac attttcaccg aggccacgcg 29761 gagtacgatc gagtgtacag tgaacaatgc tagggagagc tgcctatatg gaagagccct 29821 aatgtgtaaa attaatttta gtagtgctat ccccatgtga ttttaatagc ttcttcctgg 29881 gatcttgatt tcaacagcct cttcctcata ctattctcaa cactactgtc agtgaacttc 29941 taaaaatgga ttctgtgttt gaccgtagga aacatttcag tattccttat ctttagaaac 30001 ctctgcaact caagtgtctc tgccaaagag tcttcaaggt aatgtcaaat accataacat 30061 attttttaag tttttgtata cttcctagga atatatgtca tagtatgtaa agaagatctg 30121 attcatgtga tctgtactgt taagaaacac ttcaaaggaa aacaacctct catagatctt 30181 caaatcctgt tgttcttgag ttggaatgta caatattcag gtagagatgc tggtacaaaa 30241 aaagactgaa tcatcaggct attagaaaga taaactaggc ctctaacata gtaactttaa 30301 cagtttgtac ttatacatat tttcacattg aaatatagtt ttattcatga ctttttttgt 30361 tttagcttct ctgtcttcca ttatttcaag ctgctaaaaa ttaaaaatat cctatagcaa 30421 agggctatgg catctttttg taaaaataag gaaagcaagg ttttttgata atc https://www.ncbi.nlm.nih.gov/nuccore/mn908947

Fully annotated sequence of Wuhan-Hu-1 at Genbank

Novel Coronavirus – China Disease outbreak news : Update 12 January 2020 On 11 and 12 January 2020, WHO received further detailed information from the National Health Commission about the outbreak. WHO is reassured of the quality of the ongoing investigations and the response measures implemented in Wuhan, and the commitment to share information regularly. The evidence is highly suggestive that the outbreak is associated with exposures in one seafood market in Wuhan. The market was closed on 1 January 2020. At this stage, there is no infection among healthcare workers, and no clear evidence of human to human transmission. The Chinese authorities continue their work of intensive surveillance and follow up measures, as well as further epidemiological investigations. Among the 41 confirmed cases, there has been one death. This death occurred in a patient with serious underlying medical conditions. China shared the genetic sequence of the novel coronavirus on 12 January, which will be of great importance for other countries to use in developing specific diagnostic kits. The cluster was initially reported on 31 December 2019, when the WHO China Country Office was informed. The Chinese authorities identified a new type of coronavirus (novel coronavirus, nCoV), which was isolated on 7 January 2020. Laboratory testing was conducted on all suspected cases identified through active case finding and retrospective review. Other respiratory pathogens such as influenza, avian influenza, adenovirus, Severe Acute Respiratory Syndrome coronavirus (SARS-CoV), Middle East Respiratory Syndrome coronavirus (MERS-CoV) were ruled out as the cause. According to information conveyed to WHO by Chinese authorities on 11 and 12 January, 41 cases with novel coronavirus infection have been preliminarily diagnosed in Wuhan City. Of the 41 cases reported, seven are severely ill. This is when the one death, mentioned above, was reported, in a patient with other underlying health conditions. Six patients have been discharged from hospital. Symptom onset of the 41 confirmed nCoV cases ranges from 8 December 2019 to 2 January 2020. No additional cases have been detected since 3 January 2020. The clinical signs and symptoms reported are mainly fever, with a few cases having difficulty in breathing, and chest radiographs showing invasive pneumonic infiltrates in both lungs. National authorities report that patients have been isolated and are receiving treatment in Wuhan medical institutions. According to the preliminary epidemiological investigation, most cases worked at or were handlers and frequent visitors to the Huanan Seafood Wholesale Market. The government reports that there is no clear evidence that the virus passes easily from person to person. Currently, no case with infection of this novel coronavirus has been reported elsewhere other than Wuhan. Public Health Response China's National Health Commission has deployed a group of experts to Wuhan City to support the local response. National authorities have reported the following response measures: A total of 763 close contacts including healthcare workers, have been identified and followed up and no additional cases of infection with the novel coronavirus have been identified; The Wuhan Municipal Health Commission carried out active case finding, and retrospective investigations of the current cluster of patients have been completed The Huanan Seafood Wholesale Market has been temporarily closed to carry out environmental sanitation and disinfection; Public risk communication activities have been carried out to improve public awareness and adoption of self-protection measures. WHO is closely monitoring the situation and is in regular contact with national authorities in China to provide support required. Technical guidance on novel coronavirus has been developed and will continue to be updated as additional information is available. WHO risk assessment To date, investigations are still under way to assess the full extent of the outbreak. Wuhan city is a major domestic and international transport hub. To date, there have been no reported cases outside of Wuhan City. More comprehensive information and ongoing investigations are also required to better understand the epidemiology, clinical picture, source, modes of transmission, and extent of infection; as well as the countermeasures implemented. WHO advice Based on information provided by national authorities, WHO’s recommendations on public health measures and surveillance for novel coronaviruses apply. WHO does not recommend any specific health measures for travellers. In case of symptoms suggestive of respiratory illness either during or after travel, travellers are encouraged to seek medical attention and share travel history with their healthcare provider. Travel guidance has been updated. WHO advises against the application of any travel or trade restrictions on China based on the information currently available on this event. For more information: Technical guidance for novel coronavirus, WHO Wuhan Municipal Health Commission briefing on the pneumonia epidemic situation, 31 December 2019 (in Chinese) Wuhan Municipal Health Commission briefing on the pneumonia epidemic situation 3 January 2020 (in Chinese) Wuhan Municipal Health Commission's briefing on the pneumonia epidemic situation, 5 January 2020 (in Chinese) Wuhan Municipal Health Commission’s briefing on the pneumonia epidemic situation, 11 January 2020 (in Chinese) Wuhan Municipal Health Commission’s Experts interpretation of the outbreak update, 11 January 2020 (in Chinese) WHO travel advice for international travel and health in relation to the outbreak of pneumonia caused by a new coronavirus in China https://www.who.int/csr/don/12-january-2020-novel-coronavirus-china/en/

BetaCoV/Wuhan/WIV04/2019|EPI_ISL_402124 Top 100 matches Sequences producing significant alignments: Select:AllNone Selected:0 AlignmentsDownloadGenBankGraphicsDistance tree of resultsShow/hide columns of the table presenting sequences producing significant alignments Sequences producing significant alignments: Select for downloading or viewing reports Description Max Score Total Score Query Cover E value Per. Ident Accession Select seq MG772933.1 Bat SARS-like coronavirus isolate bat-SL-CoVZC45, complete genome 26943 35321 95% 0.0 89.12% MG772933.1 Select seq MG772934.1 Bat SARS-like coronavirus isolate bat-SL-CoVZXC21, complete genome 22223 35261 94% 0.0 88.65% MG772934.1 Select seq AY395003.1 SARS coronavirus ZS-C, complete genome 15213 22559 88% 0.0 82.34% AY395003.1 Select seq AY394996.1 SARS coronavirus ZS-B, complete genome 15213 22594 88% 0.0 82.34% AY394996.1 Select seq AY304488.1 SARS coronavirus SZ16, complete genome 15202 22531 88% 0.0 82.33% AY304488.1 Select seq AY304486.1 SARS coronavirus SZ3, complete genome 15202 22529 88% 0.0 82.33% AY304486.1 Select seq AY390556.1 SARS coronavirus GZ02, complete genome 15191 22548 88% 0.0 82.32% AY390556.1 Select seq EU371564.1 SARS coronavirus BJ182-12, complete genome 15186 22483 88% 0.0 82.32% EU371564.1 Select seq AY394985.1 SARS coronavirus HSZ-Bb, complete genome 15186 22271 87% 0.0 82.31% AY394985.1 Select seq AY278554.2 SARS coronavirus CUHK-W1, complete genome 15186 22572 88% 0.0 82.32% AY278554.2 Select seq EU371559.1 SARS coronavirus ZJ02, complete genome 15180 22548 88% 0.0 82.31% EU371559.1 Select seq AY559093.1 SARS coronavirus Sin845, complete genome 15180 22507 88% 0.0 82.31% AY559093.1 Select seq AY394994.1 SARS coronavirus HSZ-Bc, complete genome 15180 22561 88% 0.0 82.31% AY394994.1 Select seq AY394986.1 SARS coronavirus HSZ-Cb, complete genome 15180 22520 88% 0.0 82.31% AY394986.1 Select seq MK211376.1 Coronavirus BtRs-BetaCoV/YN2018B, complete genome 15176 22618 91% 0.0 82.32% MK211376.1 Select seq KY417146.1 Bat SARS-like coronavirus isolate Rs4231, complete genome 15176 22534 91% 0.0 82.30% KY417146.1 Select seq JX163927.1 SARS coronavirus isolate Tor2/FP1-10851, complete genome 15175 22417 88% 0.0 82.30% JX163927.1 Select seq JX163926.1 SARS coronavirus isolate Tor2/FP1-10912, complete genome 15175 22424 88% 0.0 82.30% JX163926.1 Select seq JX163923.1 SARS coronavirus isolate Tor2/FP1-10912, complete genome 15175 22417 88% 0.0 82.30% JX163923.1 Select seq JQ316196.1 SARS coronavirus HKU-39849 isolate UOB, complete genome 15175 22529 88% 0.0 82.30% JQ316196.1 Select seq FJ882963.1 SARS coronavirus P2, complete genome 15175 22450 88% 0.0 82.30% FJ882963.1 Select seq DQ898174.1 SARS coronavirus strain CV7, complete genome 15175 22568 88% 0.0 82.30% DQ898174.1 Select seq AY864806.1 SARS coronavirus BJ202, complete genome 15175 22574 88% 0.0 82.30% AY864806.1 Select seq AY714217.1 SARS Coronavirus CDC#200301157, complete genome 15175 22529 88% 0.0 82.30% AY714217.1 Select seq AY559096.1 SARS coronavirus Sin850, complete genome 15175 22516 88% 0.0 82.30% AY559096.1 Select seq AY559095.1 SARS coronavirus Sin847, complete genome 15175 22504 88% 0.0 82.30% AY559095.1 Select seq AY559086.1 SARS coronavirus Sin849, complete genome 15175 22502 88% 0.0 82.30% AY559086.1 Select seq AY559085.1 SARS coronavirus Sin848, complete genome 15175 22504 88% 0.0 82.30% AY559085.1 Select seq AY559084.1 SARS coronavirus Sin3765V, complete genome 15175 22526 88% 0.0 82.30% AY559084.1 Select seq AY559083.1 SARS coronavirus Sin3408, complete genome 15175 22513 88% 0.0 82.30% AY559083.1 Select seq AY559082.1 SARS coronavirus Sin852, complete genome 15175 22502 88% 0.0 82.30% AY559082.1 Select seq AY274119.3 Severe acute respiratory syndrome-related coronavirus isolate Tor2, complete genome 15175 22563 88% 0.0 82.30% AY274119.3 Select seq AY323977.2 SARS coronavirus HSR 1, complete genome 15175 22574 88% 0.0 82.30% AY323977.2 Select seq AY291451.1 SARS coronavirus TW1, complete genome 15175 22539 88% 0.0 82.30% AY291451.1 Select seq AY502928.1 SARS coronavirus TW5, complete genome 15175 22533 88% 0.0 82.30% AY502928.1 Select seq AY502926.1 SARS coronavirus TW3, complete genome 15175 22526 88% 0.0 82.30% AY502926.1 Select seq AY502923.1 SARS coronavirus TW10, complete genome 15175 22539 88% 0.0 82.30% AY502923.1 Select seq AY394999.1 SARS coronavirus LC2, complete genome 15175 22505 88% 0.0 82.30% AY394999.1 Select seq AY394998.1 SARS coronavirus LC1, complete genome 15175 22555 88% 0.0 82.30% AY394998.1 Select seq AY394995.1 SARS coronavirus HSZ-Cc, complete genome 15175 22550 88% 0.0 82.30% AY394995.1 Select seq AY394993.1 SARS coronavirus HGZ8L2, complete genome 15175 22555 88% 0.0 82.31% AY394993.1 Select seq AY394992.1 SARS coronavirus HZS2-C, complete genome 15175 22561 88% 0.0 82.31% AY394992.1 Select seq AY394991.1 SARS coronavirus HZS2-Fc, complete genome 15175 22561 88% 0.0 82.30% AY394991.1 Select seq AY394987.1 SARS coronavirus HZS2-Fb, complete genome 15175 22542 88% 0.0 82.30% AY394987.1 Select seq AY394983.1 SARS coronavirus HSZ2-A, complete genome 15175 22529 88% 0.0 82.30% AY394983.1 Select seq AY394978.1 SARS coronavirus GZ-B, complete genome 15175 22456 88% 0.0 82.30% AY394978.1 Select seq AY357075.1 SARS coronavirus PUMC02, complete genome 15175 22552 88% 0.0 82.30% AY357075.1 Select seq AY282752.2 SARS coronavirus CUHK-Su10, complete genome 15175 22555 88% 0.0 82.30% AY282752.2 Select seq AY427439.1 SARS coronavirus AS, complete genome 15175 22522 88% 0.0 82.30% AY427439.1 Select seq AY283796.1 SARS coronavirus Sin2679, complete genome 15175 22528 88% 0.0 82.30% AY283796.1 Select seq AP006561.1 SARS coronavirus TWY genomic RNA, complete genome 15175 22535 88% 0.0 82.30% AP006561.1 Select seq JX163925.1 SARS coronavirus isolate Tor2/FP1-10895, complete genome 15173 22415 88% 0.0 82.30% JX163925.1 Select seq JX163928.1 SARS coronavirus isolate Tor2/FP1-10895, complete genome 15171 22424 88% 0.0 82.30% JX163928.1 Select seq JX163924.1 SARS coronavirus isolate Tor2/FP1-10851, complete genome 15169 22420 88% 0.0 82.30% JX163924.1 Select seq GU553363.1 SARS coronavirus HKU-39849 isolate TCVSP-HARROD-00001, complete genome 15169 22415 88% 0.0 82.30% GU553363.1 Select seq EU371563.1 SARS coronavirus BJ182-8, complete genome 15169 22504 88% 0.0 82.30% EU371563.1 Select seq EU371561.1 SARS coronavirus BJ182b, complete genome 15169 22509 88% 0.0 82.30% EU371561.1 Select seq EU371560.1 SARS coronavirus BJ182a, complete genome 15169 22509 88% 0.0 82.30% EU371560.1 Select seq AY864805.1 SARS coronavirus BJ162, complete genome 15169 22568 88% 0.0 82.30% AY864805.1 Select seq AY278741.1 SARS coronavirus Urbani, complete genome 15169 22535 88% 0.0 82.30% AY278741.1 Select seq AY559087.1 SARS coronavirus Sin3725V, complete genome 15169 22518 88% 0.0 82.29% AY559087.1 Select seq AY394989.1 SARS coronavirus HZS2-D, complete genome 15169 22555 88% 0.0 82.30% AY394989.1 Select seq AY485278.1 SARS coronavirus Sino3-11, complete genome 15169 22546 88% 0.0 82.30% AY485278.1 Select seq AY502927.1 SARS coronavirus TW4, complete genome 15167 22526 88% 0.0 82.29% AY502927.1 Select seq GU553365.1 SARS coronavirus HKU-39849 isolate TCVSP-HARROD-00003, complete genome 15165 22406 88% 0.0 82.29% GU553365.1 Select seq KJ473816.1 BtRs-BetaCoV/YN2013, complete genome 15163 21673 85% 0.0 82.29% KJ473816.1 Select seq EU371562.1 SARS coronavirus BJ182-4, complete genome 15158 22498 88% 0.0 82.29% EU371562.1 Select seq MK211377.1 Coronavirus BtRs-BetaCoV/YN2018C, complete genome 15149 22403 88% 0.0 82.29% MK211377.1 Select seq KY417145.1 Bat SARS-like coronavirus isolate Rf4092, complete genome 15134 22372 87% 0.0 82.26% KY417145.1 Select seq MK211375.1 Coronavirus BtRs-BetaCoV/YN2018A, complete genome 15117 22368 89% 0.0 82.26% MK211375.1 Select seq KF294455.1 SARS-related bat coronavirus isolate Anlong-111 orf1ab polyprotein and orf1a polyprotein genes, complete cds 15084 16332 64% 0.0 82.35% KF294455.1 Select seq JX993988.1 Bat coronavirus Cp/Yunnan2011, complete genome 15043 21834 86% 0.0 82.18% JX993988.1 Select seq KJ473814.1 BtRs-BetaCoV/HuB2013, complete genome 14970 22339 87% 0.0 82.20% KJ473814.1 Select seq DQ648857.1 Bat coronavirus (BtCoV/279/2005), complete genome 14916 22163 87% 0.0 82.16% DQ648857.1 Select seq JX993987.1 Bat coronavirus Rp/Shaanxi2011, complete genome 14892 21819 88% 0.0 82.00% JX993987.1 Select seq KF294457.1 SARS-related bat coronavirus isolate Longquan-140 orf1ab polyprotein, spike glycoprotein, envelope protein, membrane protein, and nucleocapsid protein genes, complete cds 14759 23767 91% 0.0 81.89% KF294457.1 Select seq MK211374.1 Coronavirus BtRl-BetaCoV/SC2018, complete genome 14731 21836 87% 0.0 82.02% MK211374.1 Select seq KJ473813.1 BtRf-BetaCoV/SX2013, complete genome 14722 21360 87% 0.0 81.82% KJ473813.1 Select seq KJ473812.1 BtRf-BetaCoV/HeB2013, complete genome 14683 21261 87% 0.0 81.79% KJ473812.1 Select seq KJ473811.1 BtRf-BetaCoV/JL2012, complete genome 14683 21067 86% 0.0 81.79% KJ473811.1 Select seq GQ153542.1 Bat SARS coronavirus HKU3-7, complete genome 14683 21958 89% 0.0 81.82% GQ153542.1 Select seq GQ153543.1 Bat SARS coronavirus HKU3-8, complete genome 14678 21996 88% 0.0 81.82% GQ153543.1 Select seq KY770860.1 Bat coronavirus isolate Jiyuan-84, complete genome 14628 21416 87% 0.0 81.74% KY770860.1 Select seq DQ648856.1 Bat coronavirus (BtCoV/273/2005), complete genome 14556 21386 87% 0.0 81.66% DQ648856.1 Select seq DQ412042.1 Bat SARS coronavirus Rf1, complete genome 14556 21394 87% 0.0 81.66% DQ412042.1 Select seq GQ153547.1 Bat SARS coronavirus HKU3-12, complete genome 14550 21830 89% 0.0 81.68% GQ153547.1 Select seq KF294456.1 SARS-related bat coronavirus isolate Jiyuan-331 orf1ab polyprotein gene, complete cds 14539 15829 66% 0.0 81.66% KF294456.1 Select seq FJ211859.1 Recombinant coronavirus clone Bat SARS-CoV, complete sequence 14517 21875 89% 0.0 81.65% FJ211859.1 Select seq DQ084199.1 bat SARS coronavirus HKU3-2, complete genome 14512 21810 88% 0.0 81.64% DQ084199.1 Select seq GQ153540.1 Bat SARS coronavirus HKU3-5, complete genome 14506 21791 89% 0.0 81.63% GQ153540.1 Select seq GQ153539.1 Bat SARS coronavirus HKU3-4, complete genome 14506 21797 89% 0.0 81.63% GQ153539.1 Select seq GQ153546.1 Bat SARS coronavirus HKU3-11, complete genome 14501 21780 89% 0.0 81.63% GQ153546.1 Select seq DQ022305.2 Bat SARS coronavirus HKU3-1, complete genome 14501 21858 89% 0.0 81.63% DQ022305.2 Select seq DQ084200.1 bat SARS coronavirus HKU3-3, complete genome 14501 21843 89% 0.0 81.63% DQ084200.1 Select seq GQ153548.1 Bat SARS coronavirus HKU3-13, complete genome 14495 21769 89% 0.0 81.63% GQ153548.1 Select seq GQ153541.1 Bat SARS coronavirus HKU3-6, complete genome 14495 21797 89% 0.0 81.62% GQ153541.1 Select seq GQ153545.1 Bat SARS coronavirus HKU3-10, complete genome 14484 21758 89% 0.0 81.61% GQ153545.1 Select seq GQ153544.1 Bat SARS coronavirus HKU3-9, complete genome 14484 21758 89% 0.0 81.61% GQ153544.1 Select seq KU182964.1 Bat coronavirus isolate JTMC15, complete genome 13501 20280 79% 0.0 82.94% KU182964.1 Select seq KY938558.1 Bat coronavirus strain 16BO133, complete genome 13452 20206 79% 0.0 82.88% KY938558.1

BetaCoV/Wuhan/IPBCAMS-WH-01/2019|EPI_ISL_402123 Top 100 matches at Genbank Sequences producing significant alignments: Select:AllNone Selected:0 AlignmentsDownloadGenBankGraphicsDistance tree of resultsShow/hide columns of the table presenting sequences producing significant alignments Sequences producing significant alignments: Select for downloading or viewing reports Description Max Score Total Score Query Cover E value Per. Ident Accession Select seq MG772933.1 Bat SARS-like coronavirus isolate bat-SL-CoVZC45, complete genome 26927 35319 95% 0.0 89.10% MG772933.1 Select seq MG772934.1 Bat SARS-like coronavirus isolate bat-SL-CoVZXC21, complete genome 22207 35259 94% 0.0 88.64% MG772934.1 Select seq AY395003.1 SARS coronavirus ZS-C, complete genome 15202 22553 88% 0.0 82.33% AY395003.1 Select seq AY394996.1 SARS coronavirus ZS-B, complete genome 15202 22589 88% 0.0 82.33% AY394996.1 Select seq AY304488.1 SARS coronavirus SZ16, complete genome 15191 22520 88% 0.0 82.32% AY304488.1 Select seq AY304486.1 SARS coronavirus SZ3, complete genome 15191 22518 88% 0.0 82.32% AY304486.1 Select seq AY390556.1 SARS coronavirus GZ02, complete genome 15180 22537 88% 0.0 82.31% AY390556.1 Select seq EU371564.1 SARS coronavirus BJ182-12, complete genome 15175 22472 88% 0.0 82.30% EU371564.1 Select seq AY394985.1 SARS coronavirus HSZ-Bb, complete genome 15175 22265 87% 0.0 82.30% AY394985.1 Select seq AY278554.2 SARS coronavirus CUHK-W1, complete genome 15175 22566 88% 0.0 82.30% AY278554.2 Select seq EU371559.1 SARS coronavirus ZJ02, complete genome 15169 22537 88% 0.0 82.30% EU371559.1 Select seq AY559093.1 SARS coronavirus Sin845, complete genome 15169 22496 88% 0.0 82.30% AY559093.1 Select seq AY394994.1 SARS coronavirus HSZ-Bc, complete genome 15169 22555 88% 0.0 82.30% AY394994.1 Select seq AY394986.1 SARS coronavirus HSZ-Cb, complete genome 15169 22515 88% 0.0 82.30% AY394986.1 Select seq MK211376.1 Coronavirus BtRs-BetaCoV/YN2018B, complete genome 15165 22607 91% 0.0 82.31% MK211376.1 Select seq KY417146.1 Bat SARS-like coronavirus isolate Rs4231, complete genome 15165 22523 91% 0.0 82.29% KY417146.1 Select seq JX163927.1 SARS coronavirus isolate Tor2/FP1-10851, complete genome 15163 22406 88% 0.0 82.29% JX163927.1 Select seq JX163926.1 SARS coronavirus isolate Tor2/FP1-10912, complete genome 15163 22413 88% 0.0 82.29% JX163926.1 Select seq JX163923.1 SARS coronavirus isolate Tor2/FP1-10912, complete genome 15163 22406 88% 0.0 82.29% JX163923.1 Select seq JQ316196.1 SARS coronavirus HKU-39849 isolate UOB, complete genome 15163 22518 88% 0.0 82.29% JQ316196.1 Select seq FJ882963.1 SARS coronavirus P2, complete genome 15163 22439 88% 0.0 82.29% FJ882963.1 Select seq DQ898174.1 SARS coronavirus strain CV7, complete genome 15163 22563 88% 0.0 82.29% DQ898174.1 Select seq AY864806.1 SARS coronavirus BJ202, complete genome 15163 22568 88% 0.0 82.29% AY864806.1 Select seq AY714217.1 SARS Coronavirus CDC#200301157, complete genome 15163 22518 88% 0.0 82.29% AY714217.1 Select seq AY559096.1 SARS coronavirus Sin850, complete genome 15163 22505 88% 0.0 82.29% AY559096.1 Select seq AY559095.1 SARS coronavirus Sin847, complete genome 15163 22492 88% 0.0 82.29% AY559095.1 Select seq AY559086.1 SARS coronavirus Sin849, complete genome 15163 22491 88% 0.0 82.29% AY559086.1 Select seq AY559085.1 SARS coronavirus Sin848, complete genome 15163 22492 88% 0.0 82.29% AY559085.1 Select seq AY559084.1 SARS coronavirus Sin3765V, complete genome 15163 22515 88% 0.0 82.29% AY559084.1 Select seq AY559083.1 SARS coronavirus Sin3408, complete genome 15163 22502 88% 0.0 82.29% AY559083.1 Select seq AY559082.1 SARS coronavirus Sin852, complete genome 15163 22491 88% 0.0 82.29% AY559082.1 Select seq AY274119.3 Severe acute respiratory syndrome-related coronavirus isolate Tor2, complete genome 15163 22557 88% 0.0 82.29% AY274119.3 Select seq AY323977.2 SARS coronavirus HSR 1, complete genome 15163 22568 88% 0.0 82.29% AY323977.2 Select seq AY291451.1 SARS coronavirus TW1, complete genome 15163 22528 88% 0.0 82.29% AY291451.1 Select seq AY502928.1 SARS coronavirus TW5, complete genome 15163 22522 88% 0.0 82.29% AY502928.1 Select seq AY502926.1 SARS coronavirus TW3, complete genome 15163 22515 88% 0.0 82.29% AY502926.1 Select seq AY502923.1 SARS coronavirus TW10, complete genome 15163 22528 88% 0.0 82.29% AY502923.1 Select seq AY394999.1 SARS coronavirus LC2, complete genome 15163 22500 88% 0.0 82.29% AY394999.1 Select seq AY394998.1 SARS coronavirus LC1, complete genome 15163 22550 88% 0.0 82.29% AY394998.1 Select seq AY394995.1 SARS coronavirus HSZ-Cc, complete genome 15163 22544 88% 0.0 82.29% AY394995.1 Select seq AY394993.1 SARS coronavirus HGZ8L2, complete genome 15163 22550 88% 0.0 82.29% AY394993.1 Select seq AY394992.1 SARS coronavirus HZS2-C, complete genome 15163 22555 88% 0.0 82.29% AY394992.1 Select seq AY394991.1 SARS coronavirus HZS2-Fc, complete genome 15163 22555 88% 0.0 82.29% AY394991.1 Select seq AY394987.1 SARS coronavirus HZS2-Fb, complete genome 15163 22537 88% 0.0 82.29% AY394987.1 Select seq AY394983.1 SARS coronavirus HSZ2-A, complete genome 15163 22524 88% 0.0 82.29% AY394983.1 Select seq AY394978.1 SARS coronavirus GZ-B, complete genome 15163 22450 88% 0.0 82.29% AY394978.1 Select seq AY357075.1 SARS coronavirus PUMC02, complete genome 15163 22552 88% 0.0 82.29% AY357075.1 Select seq AY282752.2 SARS coronavirus CUHK-Su10, complete genome 15163 22550 88% 0.0 82.29% AY282752.2 Select seq AY427439.1 SARS coronavirus AS, complete genome 15163 22511 88% 0.0 82.29% AY427439.1 Select seq AY283796.1 SARS coronavirus Sin2679, complete genome 15163 22516 88% 0.0 82.29% AY283796.1 Select seq AP006561.1 SARS coronavirus TWY genomic RNA, complete genome 15163 22524 88% 0.0 82.29% AP006561.1 Select seq JX163925.1 SARS coronavirus isolate Tor2/FP1-10895, complete genome 15162 22404 88% 0.0 82.29% JX163925.1 Select seq JX163928.1 SARS coronavirus isolate Tor2/FP1-10895, complete genome 15160 22413 88% 0.0 82.29% JX163928.1 Select seq JX163924.1 SARS coronavirus isolate Tor2/FP1-10851, complete genome 15158 22409 88% 0.0 82.29% JX163924.1 Select seq GU553363.1 SARS coronavirus HKU-39849 isolate TCVSP-HARROD-00001, complete genome 15158 22404 88% 0.0 82.29% GU553363.1 Select seq EU371563.1 SARS coronavirus BJ182-8, complete genome 15158 22492 88% 0.0 82.29% EU371563.1 Select seq EU371561.1 SARS coronavirus BJ182b, complete genome 15158 22498 88% 0.0 82.29% EU371561.1 Select seq EU371560.1 SARS coronavirus BJ182a, complete genome 15158 22498 88% 0.0 82.29% EU371560.1 Select seq AY864805.1 SARS coronavirus BJ162, complete genome 15158 22563 88% 0.0 82.29% AY864805.1 Select seq AY278741.1 SARS coronavirus Urbani, complete genome 15158 22524 88% 0.0 82.29% AY278741.1 Select seq AY559087.1 SARS coronavirus Sin3725V, complete genome 15158 22507 88% 0.0 82.28% AY559087.1 Select seq AY394989.1 SARS coronavirus HZS2-D, complete genome 15158 22550 88% 0.0 82.29% AY394989.1 Select seq AY485278.1 SARS coronavirus Sino3-11, complete genome 15158 22535 88% 0.0 82.29% AY485278.1 Select seq AY502927.1 SARS coronavirus TW4, complete genome 15156 22515 88% 0.0 82.28% AY502927.1 Select seq GU553365.1 SARS coronavirus HKU-39849 isolate TCVSP-HARROD-00003, complete genome 15154 22395 88% 0.0 82.28% GU553365.1 Select seq KJ473816.1 BtRs-BetaCoV/YN2013, complete genome 15152 21661 85% 0.0 82.28% KJ473816.1 Select seq EU371562.1 SARS coronavirus BJ182-4, complete genome 15147 22487 88% 0.0 82.28% EU371562.1 Select seq MK211377.1 Coronavirus BtRs-BetaCoV/YN2018C, complete genome 15138 22392 88% 0.0 82.28% MK211377.1 Select seq KY417145.1 Bat SARS-like coronavirus isolate Rf4092, complete genome 15123 22361 86% 0.0 82.25% KY417145.1 Select seq MK211375.1 Coronavirus BtRs-BetaCoV/YN2018A, complete genome 15106 22357 88% 0.0 82.25% MK211375.1 Select seq KF294455.1 SARS-related bat coronavirus isolate Anlong-111 orf1ab polyprotein and orf1a polyprotein genes, complete cds 15073 16321 64% 0.0 82.34% KF294455.1 Select seq JX993988.1 Bat coronavirus Cp/Yunnan2011, complete genome 15032 21823 86% 0.0 82.17% JX993988.1 Select seq KJ473814.1 BtRs-BetaCoV/HuB2013, complete genome 14958 22328 87% 0.0 82.19% KJ473814.1 Select seq DQ648857.1 Bat coronavirus (BtCoV/279/2005), complete genome 14905 22152 87% 0.0 82.15% DQ648857.1 Select seq JX993987.1 Bat coronavirus Rp/Shaanxi2011, complete genome 14881 21808 88% 0.0 81.99% JX993987.1 Select seq KF294457.1 SARS-related bat coronavirus isolate Longquan-140 orf1ab polyprotein, spike glycoprotein, envelope protein, membrane protein, and nucleocapsid protein genes, complete cds 14748 23756 91% 0.0 81.88% KF294457.1 Select seq MK211374.1 Coronavirus BtRl-BetaCoV/SC2018, complete genome 14720 21825 87% 0.0 82.00% MK211374.1 Select seq KJ473813.1 BtRf-BetaCoV/SX2013, complete genome 14711 21349 87% 0.0 81.81% KJ473813.1 Select seq KJ473812.1 BtRf-BetaCoV/HeB2013, complete genome 14672 21250 86% 0.0 81.78% KJ473812.1 Select seq KJ473811.1 BtRf-BetaCoV/JL2012, complete genome 14672 21056 86% 0.0 81.78% KJ473811.1 Select seq GQ153542.1 Bat SARS coronavirus HKU3-7, complete genome 14672 21947 88% 0.0 81.81% GQ153542.1 Select seq GQ153543.1 Bat SARS coronavirus HKU3-8, complete genome 14667 21985 88% 0.0 81.80% GQ153543.1 Select seq KY770860.1 Bat coronavirus isolate Jiyuan-84, complete genome 14617 21405 87% 0.0 81.73% KY770860.1 Select seq DQ648856.1 Bat coronavirus (BtCoV/273/2005), complete genome 14545 21375 87% 0.0 81.65% DQ648856.1 Select seq DQ412042.1 Bat SARS coronavirus Rf1, complete genome 14545 21383 87% 0.0 81.65% DQ412042.1 Select seq GQ153547.1 Bat SARS coronavirus HKU3-12, complete genome 14539 21819 88% 0.0 81.67% GQ153547.1 Select seq KF294456.1 SARS-related bat coronavirus isolate Jiyuan-331 orf1ab polyprotein gene, complete cds 14528 15818 66% 0.0 81.65% KF294456.1 Select seq FJ211859.1 Recombinant coronavirus clone Bat SARS-CoV, complete sequence 14506 21867 89% 0.0 81.63% FJ211859.1 Select seq DQ084199.1 bat SARS coronavirus HKU3-2, complete genome 14501 21799 88% 0.0 81.63% DQ084199.1 Select seq GQ153540.1 Bat SARS coronavirus HKU3-5, complete genome 14495 21780 88% 0.0 81.62% GQ153540.1 Select seq GQ153539.1 Bat SARS coronavirus HKU3-4, complete genome 14495 21786 88% 0.0 81.62% GQ153539.1 Select seq GQ153546.1 Bat SARS coronavirus HKU3-11, complete genome 14489 21769 88% 0.0 81.62% GQ153546.1 Select seq DQ022305.2 Bat SARS coronavirus HKU3-1, complete genome 14489 21852 89% 0.0 81.62% DQ022305.2 Select seq DQ084200.1 bat SARS coronavirus HKU3-3, complete genome 14489 21838 89% 0.0 81.62% DQ084200.1 Select seq GQ153548.1 Bat SARS coronavirus HKU3-13, complete genome 14484 21758 88% 0.0 81.61% GQ153548.1 Select seq GQ153541.1 Bat SARS coronavirus HKU3-6, complete genome 14484 21786 88% 0.0 81.61% GQ153541.1 Select seq GQ153545.1 Bat SARS coronavirus HKU3-10, complete genome 14473 21747 88% 0.0 81.60% GQ153545.1 Select seq GQ153544.1 Bat SARS coronavirus HKU3-9, complete genome 14473 21747 88% 0.0 81.60% GQ153544.1 Select seq KU182964.1 Bat coronavirus isolate JTMC15, complete genome 13490 20269 79% 0.0 82.93% KU182964.1 Select seq KY938558.1 Bat coronavirus strain 16BO133, complete genome 13441 20195 79% 0.0 82.87% KY938558.1