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Virus detail Virus name: BetaCoV/Wuhan/HBCDC-HB-01/2019 Accession ID: EPI_ISL_402132 Type: betacoronavirus Passage details/history: Original Sample information Collection date: 2019-12-30 Location: China/Hubei Province Host: Human Additional location information:

Virus name: BetaCoV/Wuhan/WIV02/2019 Accession ID: EPI_ISL_402127 Type: betacoronavirus Passage details/history: Original Sample information Collection date: 2019-12-30 Location: China / Hubei Province / Wuhan City Host: Human Additional location information: 5' and 3' Race was not performed

Virus name: BetaCoV/Wuhan/WIV05/2019 Accession ID: EPI_ISL_402128 Type: betacoronavirus Passage details/history: Original Sample information Collection date: 2019-12-30 Location: China / Hubei Province / Wuhan City Host: Human Additional location information: 5' and 3' Race was not performed

Virus name: BetaCoV/Wuhan/WIV06/2019 Accession ID: EPI_ISL_402129 Type: betacoronavirus Passage details/history: Original Sample information Collection date: 2019-12-30 Location: China / Hubei Province / Wuhan City Host: Human Additional location information: 5' and 3' Race was not performed

Virus name: BetaCoV/Wuhan/WIV07/2019 Accession ID: EPI_ISL_402130 Type: betacoronavirus Passage details/history: Original Sample information Collection date: 2019-12-30 Location: China / Hubei Province / Wuhan City Host: Human Additional location information: 5' and 3' Race was not performed

Latest News Indian School Teacher Diagnosed with Streptococcal Infection, Under Treatment January 19, 2020 Healthwire Bureau K J M Varma Beijing, Janaury19-A 45-year-old Indian school teacher in the Chinese city of Shenzhen is undergoing treatment for a Streptococcal infection which was initially suspected to be a case of mysterious SARS-like coronavirus prevalent in the country. Preeti Maheshwari, a teacher at an international school in Shenzhen, is being treated for Streptococcal infection, her husband Ashuman Khowal told PTI from Shenzhen. He said the doctors said she was being treated for the infection in the intensive care unit and is currently on a ventilator and other supporting systems. Initially it was suspected that Maheshwari may have been suffering from a new type of coronavirus. Khowal, however, clarified that his wife case had been diagnosed as Streptococcal infection. Chinese city of Wuhan is currently under the grip of a new mysterious viral pneumonia. According to the official media reports, tentative diagnosis of the pneumonia is caused by a coronavirus. The virus has caused alarm because of its connection to SARS (Severe Acute Respiratory Syndrome) which killed nearly 650 people in China and Hong Kong in 2002-2003. According to the reports from Wuhan, where the virus started surfacing few weeks ago, 17 new cases have been reported, taking the total number of cases to 62. A total of 19 have been cured and discharged from the hospital, and the rest remain in isolation and are receiving treatment, state-run Xinhua news agency reported on Sunday. Two people in Shenzhen are currently in quarantine at the Third People’s Hospital, which specialises in the treatment of infectious diseases, Hong Kong-based South China Morning Post reported. India on Friday issued an advisory to its nationals visiting China following a second death due to the outbreak of the new strain of pneumonia in the Chinese city of Wuhan where over 500 Indian medical students are studying. “An infection with a novel coronavirus has been reported from China. As on 11th January, 2020, 41 confirmed cases have been reported so far,” said the travel warning issued by India. Travel-related cases have been reported one each in Thailand and Japan. Over 500 Indian students study in the Wuhan city’s medical colleges in universities. Most of them appear to have left for home for the Chinese New Year holidays. The clinical signs and symptoms of coronavirus infection are mainly fever with a few patients having difficulty in breathing, the Indian travel warning said. Mode of transmission is unclear as of now. However, so far there is little evidence of significant human- to-human transmission, it said. The patients showed symptoms such as fever or cough, the Wuhan Municipal Health Commission said. Epidemiological investigations into the 17 new cases are underway and close contacts are being traced, the authority said, adding that Wuhan will continue to expand the search area, identify suspected cases and conduct sampling tests. Epidemiological analysis of previously published cases found that some cases had no exposure to Wuhan’s Huanan Seafood Wholesale Market, which is believed to be related to most of the infected cases. It has been temporarily closed while disinfection is carried out, the Xinhua report said. A total of 681 among 763 close contacts who were placed under medical observation have been released. No cases were found among the close contacts. (PTI) https://healthwire.co/indian-school-teacher-diagnosed-with-streptococcal-infection-under-treatment/

Indian school teacher becomes first foreigner to contract coronavirus in China A 45-year-old Indian school teacher is undergoing treatment for a new strain of pneumonia outbreak spreading in the Chinese cities of Wuhan and Shenzhen, becoming the first foreigner to have contracted the mysterious SARS-like coronavirus. ADVERTISEMENT Press Trust of India Beijing January 19, 2020 UPDATED: January 19, 2020 18:44 IST Japanese govt said a man treated for pneumonia after returning from China has tested positive for the new coronavirus identified as a possible cause of an outbreak in the Chinese city of Wuhan. (Photo: AP) A45-year-old Indian school teacher is undergoing treatment for a new strain of pneumonia outbreak spreading in the Chinese cities of Wuhan and Shenzhen, becoming the first foreigner to have contracted the mysterious SARS-like coronavirus. Preeti Maheshwari, a teacher at an international school in Shenzhen, has been admitted to a local hospital after she fell seriously ill last Friday. Doctors on Monday confirmed that she was suffering from the virus and is being treated for it, her husband Ashuman Khowal told PTI from Shenzhen. The virus has caused alarm because of its connection to SARS (Severe Acute Respiratory Syndrome) which killed nearly 650 people in China and Hong Kong in 2002-2003. Khowal, a businessman from Delhi, said Maheswari was being treated in the intensive care unit and is currently on a ventilator and other supporting systems. Khowal, who is allowed to visit the patient for a few hours every day, said she was unconscious and doctors have said she could take a long time to recover. According to the reports from Wuhan, where the virus started surfacing few weeks ago, 17 new cases have been reported, taking the total number of cases to 62. A total of 19 have been cured and discharged from the hospital, and the rest remain in isolation and are receiving treatment, state-run Xinhua news agency reported on Sunday. Two people in Shenzhen are currently in quarantine at the Third People's Hospital, which specialises in the treatment of infectious diseases, Hong Kong-based South China Morning Post reported. India on Friday issued an advisory to its nationals visiting China following a second death due to the outbreak of the new strain of pneumonia in the Chinese city of Wuhan where over 500 Indian medical students are studying. "An infection with a novel coronavirus has been reported from China. As on 11th January, 2020, 41 confirmed cases have been reported so far," said the travel warning issued by India. Travel-related cases have been reported one each in Thailand and Japan. Over 500 Indian students study in the Wuhan city's medical colleges in universities. But most of them appear to have left for home for the Chinese New Year holidays. The clinical signs and symptoms are mainly fever with a few patients having difficulty in breathing, the Indian travel warning said. Mode of transmission is unclear as of now. However, so far there is little evidence of significant human- to-human transmission, it said. The patients showed symptoms such as fever or cough, the Wuhan Municipal Health Commission said. Epidemiological investigations into the 17 new cases are underway and close contacts are being traced, the authority said, adding that Wuhan will continue to expand the search area, identify suspected cases and conduct sampling tests. Epidemiological analysis of previously published cases found that some cases had no exposure to Wuhan's Huanan Seafood Wholesale Market, which is believed to be related to most of the infected cases. It has been temporarily closed while disinfection is carried out, the Xinhua report said. A total of 681 among 763 close contacts who were placed under medical observation have been released. No cases were found among the close contacts. https://www.indiatoday.in/india/story/coronavirus-indian-school-teacher-1638293-2020-01-19

Coronavirus: China reports 17 new cases of Sars-like mystery virus Three of the new cases are severe, with experts worried about the disease’s spread ahead of lunar new year Staff carry a patient into the Jinyintan hospital, where patients infected by a mysterious Sars-like virus are being treated, in Wuhan. Photograph: STR/AFP via Getty Images China reported 17 new cases of the mysterious Sars-like virus on Sunday, including three in a severe condition, heightening fears ahead of China’s lunar new year holiday, when hundreds of millions of people move around the country. The new coronavirus strain has caused alarm because of its connection to severe acute respiratory syndrome, which killed nearly 650 people across mainland China and Hong Kong in 2002-03. Of the 17 new cases in the central city of Wuhan – believed to be the epicentre of the outbreak – three were described as “severe”, with two patients were too critical to be moved, authorities said. China's Sars-like illness worries health experts Read more Those infected range from 30 to 79 years old. The virus has now infected 62 people in Wuhan, city authorities said, with eight in a severe condition, 19 cured and discharged from hospital, and the rest remaining in isolation receiving treatment. Two people have died so far from the virus, including a 69-year-old man who died on Wednesday after the disease caused pulmonary tuberculosis and damaged multiple organ functions. Authorities said they had begun “optimised” testing of pneumonia cases across the city to identify those infected, and would begin “detection work ... towards suspected cases in the city” as a next step, as well as carrying out “sampling tests”. Scientists with the MRC Centre for Global Infectious Disease Analysis at Imperial College in London warned in a paper published on Friday that the number of cases in the city was likely to be closer to 1,700, much higher than the number officially identified. Authorities said on Sunday that some of the cases had “no history of contact” with the seafood market believed to be the centre of the outbreak. No human-to-human transmission has been confirmed so far, but Wuhan’s health commission has previously said the possibility “cannot be excluded”. Three cases have also been reported overseas – two in Thailand and one in Japan. Although there has been no official announcement of screening measures on the mainland, Wuhan deputy mayor Chen Xiexin said on state broadcaster CCTV that infrared thermometers had been installed at airports, railway stations and coach stations across the city. Chen said passengers with fevers were being registered, given masks and taken to medical institutions, with nearly 300,000 body temperature tests carried out, according to CCTV. Coronavirus: Australia's top health official says there is 'no current need' to enhance airport screening Read more Authorities in Hong Kong have stepped up detection measures, including rigorous temperature checkpoints for inbound travellers from the Chinese mainland. The US said from Friday it would begin screening direct flights arriving from Wuhan at San Francisco airport and New York’s JFK, as well as Los Angeles, where many flights connect. Thailand said it was already screening passengers arriving in Bangkok, Chiang Mai and Phuket and would soon introduce similar controls in the beach resort of Krabi. Wuhan is a city of 11 million inhabitants that serves as a major transport hub, including during the annual lunar new year holiday starting this week, when hundreds of millions of Chinese people travel across the country to visit family. https://www.theguardian.com/world/2020/jan/19/coronavirus-china-reports-17-new-cases-of-sars-like-mystery-virus

World Health Organization Western Pacific @WHOWPRO · 1h Replying to @WHOWPRO Chinese authorities advise the new cases were found because of enhanced & expanded surveillance. Some appear not to be linked to Huanan market. Because of a Govt call last week to implement broader screening, cases may be identified in other parts of China in coming days & weeks.

Virus name: BetaCoV/Nonthaburi/74/2020 Accession ID: EPI_ISL_403963 Type: betacoronavirus Passage details/history: Original Sample information Collection date: 2020-01-13 Location: Thailand/ Nonthaburi Province Host: Human

Virus name: BetaCoV/Nonthaburi/61/2020 Accession ID: EPI_ISL_403962 Type: betacoronavirus Passage details/history: Original Sample information Collection date: 2020-01-08 Location: Thailand/ Nonthaburi Province Host: Human

Wuhan Municipal Commission of Health and Health on pneumonia of new coronavirus infection Issuing authority: Wuhan City health committee | Published: 2020-01-19 00:43:34 | Hits: 1679 | At 04:00 on January 17, 2020, 4 patients were cured and discharged, with 17 new cases and no deaths. Analysis of the epidemiological data of the previously released cases of pneumonitis infected by the new coronavirus found that some cases had no history of contact with the South China Seafood Wholesale Market. On the basis of standardizing pre-screening triage and fever diagnosis, optimized test kits were used to sample and monitor unidentified pneumonia cases for fever diagnosis and isolation in the city, and 17 new types of coronavirus positive were detected. After comprehensive research and judgment by clinical experts, 17 cases were confirmed as confirmed cases , and all were treated in Wuhan Jinyintan Hospital and related designated hospitals . Of the 17 newly diagnosed cases, 3 were severe cases. The next step will continue to carry out the detection of suspected cases in the city. As of 24:00 on January 17, 62 cases of pneumonitis with new coronavirus infection have been reported in our city, 19 cases have been cured and discharged, 8 cases are being treated in severe cases, and 2 cases have died. The remaining patients are in stable condition. Institution receives isolation treatment. A total of 763 close contacts have been tracked, 681 medical observations have been lifted, and 82 people are still receiving medical observations. Among the close contacts, no related cases were found. Epidemiological investigations of new cases and follow-up investigations of close contacts are ongoing. http://wjw.wuhan.gov.cn/front/web/showDetail/2020011909074 January 18, 2020

Suddenly there are 17 new 2019-nCoV confirmed cases in Wuhan.

However, three separate sources have told the South China Morning Post that at least two suspected cases have been reported in the south China city of Shenzhen, and a third in Shanghai, in the east of the country. The two people in Shenzhen are currently in quarantine at the Third People’s Hospital, which specialises in the treatment of infectious diseases, the sources said. https://www.scmp.com/news/china/society/article/3046681/china-coronavirus-least-three-suspected-cases-found-shenzhen

Suspect 2019-nCoV cases are being reported in Shezhen, Guangdong infectious disease hospital. Suspect and confirmed nCoV cases will be reported here.

US CDC issued a health alert (HAN) at 8:30 PM ET on a Friday night. Background below (emphasis added) BackgroundAn outbreak of pneumonia of unknown etiology in Wuhan City was initially reported to WHO on December 31, 2019. Chinese health authorities have confirmed more than 40 infections with a novel coronavirus as the cause of the outbreak. Reportedly, most patients had epidemiological links to a large seafood and animal market. The market was closed on January 1, 2020. Currently, Chinese health authorities report no community spread of this virus, and no transmission among healthcare personnel caring for outbreak patients. No additional cases of infection with 2019-nCoV have been identified in China since January 3, 2020. https://emergency.cdc.gov/han/han00426.asp

Wuhan pneumonia outbreak? Chinese netizen Weibo broke the news: hospitals often lay on the corridor Chinese officials estimate that the number of "Chinese Spring Festival" transports will reach 3 billion. The Chinese people are worried about whether the epidemic is accelerating due to the huge crowds. (AFP News photo) 2020-01-17 22:01:05 [Real-time news / comprehensive report] The outbreak of the new coronavirus (2019-nCoV) in Wuhan, China in 2019, and similar cases in Hong Kong, Thailand, and Japan. A Chinese netizen posted a Weibo and pointed out that when he entered the hospital, he found all patients with fever. "Many people are lying on the floor of the corridor." He and his family had injections, but the situation did not improve, and he did not know if I feel helpless where to go for treatment. Chinese netizen "Mr. Shusss" said on Weibo on the 16th that his father began to feel unwell on the 9th and had a low fever. After computer tomography and blood tests, he confirmed that the virus and lungs had shadows. The text said that his father did not improve after receiving 3 days of treatment, so he had to go to a specialized clinic of Wuhan Tongji Hospital. "All the patients entering the hospital were fever patients, and many people were lying on the floor in the corridor." The article wrote that after his father had a checkup and 2 days of injections, because the hospital did not have a bed, he was instructed to "go home and isolate" according to the doctor's instructions. Because the condition was really bad, he was eventually transferred to Jinyintan Hospital. "Mr. Shusss" said that he and his mother have had a fever for 3 days, his lungs were infected, and the injection was done for 2 days, but they did not improve. They did not know where to go for treatment, and the Jinyintan Hospital did not have an outpatient department. "Now helpless." At the end of the article, "Mr. Shusss" added, "About this pneumonia, I think it is necessary to tell the situation, and I am responsible for the above remarks." This article also caused heated discussion among Chinese netizens. Regarding some netizens questioning that "rumor-making caused panic", the original PO insisted that it was not exaggerated, but because of fear of negative impact on themselves, the article has been deleted. This breaking account was later renamed "jgxrssu". According to the official website of the Wuhan Municipal Health and Health Committee, there are currently 41 cases of Wuhan pneumonia accumulated in the local area, 12 cases have been cured, 5 cases have been cured, and 2 cases have died. On the seventh day of the "Chinese Spring Festival", Chinese officials estimate that the number of transports will reach 3 billion. With the huge crowds going back and forth, the Chinese people are quite worried about whether to accelerate the spread of the epidemic. https://news.ltn.com.tw/news/world/breakingnews/3043564?fbclid=IwAR1duQM0N_dFCpz8gP-nRwTWPremZPDTEQMo9SUf-Sct5xcA2c2c67ymliI

Jan 17 update on 2nd export to Thailand and increased airport screenings / concerns about under reported cases http://recombinomics.co/thedrnimanshow/2020/01/011720.mp3

3. Related situation of close contacts of confirmed cases abroad Seventeen Thai close contacts of the first confirmed patients were tracked, all of which were included in medical observations. One of them had symptoms of low fever and mild cough, and has been transferred to designated hospitals for treatment. Personnel information, tracking of close family contacts is under way; 4 cases of close family contacts have been tracked for patients with confirmed cases notified in Japan, all of which have been included in medical observation. http://wjw.wuhan.gov.cn/front/web/showDetail/2020011809065

Press Release Embargoed until 2:00 pm Friday, January 17, 2020 Contact: CDC Media Relations (404) 639-3286 Public Health Screening to Begin at 3 U.S. Airports for 2019 Novel Coronavirus (“2019-nCoV”) The Centers for Disease Control and Prevention (CDC) and the Department of Homeland Security’s Customs and Border Protection (CBP) will implement enhanced health screenings to detect ill travelers traveling to the United States on direct or connecting flights from Wuhan, China. This activity is in response to an outbreak in China caused by a novel (new) coronavirus (2019 nCoV), with exported cases to Thailand and Japan. Starting January 17, 2020, travelers from Wuhan to the United States will undergo entry screening for symptoms associated with 2019-nCoV at three U.S. airports that receive most of the travelers from Wuhan, China: San Francisco (SFO), New York (JFK), and Los Angeles (LAX) airports. “To further protect the health of the American public during the emergence of this novel coronavirus, CDC is beginning entry screening at three ports of entry. Investigations into this novel coronavirus are ongoing and we are monitoring and responding to this evolving situation,” said Martin Cetron, M.D., Director of CDC’s Division of Global Migration and Quarantine. Based on current information, the risk from 2019-nCoV to the American public is currently deemed to be low. Nevertheless, CDC is taking proactive preparedness precautions. Entry screening is part of a layered approach used with other public health measures already in place to detect arriving travelers who are sick (such as detection and reporting of ill travelers by airlines during travel and referral of ill travelers arriving at a US port of entry by CBP) to slow and reduce the spread of any disease into the United States. CDC is deploying about 100 additional staff to the three airports (SFO, JFK, and LAX) to supplement existing staff at CDC quarantine stations located at those airports. CDC is actively monitoring this situation for pertinent information about the source of outbreak, and risk for further spread through person-to-person or animal-to-person transmission. CDC may adjust screening procedures and other response activities as this outbreak investigation continues and more is learned about the newly emerging virus. Entry screening alone is not a guarantee against the possible importation of this new virus but is an important public health tool during periods of uncertainty and part of a multilayered government response strategy. As new information emerges, CDC will reassess entry screening measures and could scale activities up or down accordingly. On Jan. 11, 2020, CDC updated a Level 1 Travel Health Notice (“practice usual precautions”) for travelers to Wuhan City and an updated Health Alert to health care professionals and public health partners with new and updated guidance is forthcoming. China health officials report that most of the patients infected with 2019-nCoV have had exposure to a large market where live animals were present, suggesting this is a novel virus that has jumped the species barrier to infect people. Chinese authorities additionally report that several hundred health care workers caring for outbreak patients are being monitored and no spread of this virus from patients to health care workers has been seen. They report no sustained spread of this virus in the community, however there are indications that some limited person-to-person spread may have occurred. CDC is responding to this outbreak out of an abundance of caution, ready to detect people infected with 2019-CoV. For the latest information on the outbreak, visit CDC’s Novel Coronavirus 2019 website.

Most flight destinations from Wuhan are in SE Asia.

Rapid Risk Assessment: Cluster of pneumonia cases caused by a novel coronavirus, Wuhan, China, 2020 Risk assessment 17 Jan 2020 Cite: Citation Link TwitterFacebookLinked InMail The likelihood of importation of cases of novel coronavirus (2019-nCoV) to the EU is considered to be low, but cannot be excluded in the current situation.This document presents disease background, risk assessment and options for response. Executive summary A novel coronavirus (2019-nCoV) has been isolated and considered the causative agent of the cluster of 41 pneumonia cases in the area of Wuhan, Hubei province in China, and three travel-related cases in Thailand and Japan, arriving from Wuhan. The majority of detected pneumonia cases reported having visited the Wuhan Huanan Seafood Wholesale Market recently before disease onset. Some cases did not report any exposure to this specific market, but to other food markets in Wuhan. For a few cases there was no direct connection with a food market. The Wuhan Huanan Seafood Wholesale Market has been closed and disinfected. However, there is no information available on restrictions at other food markets in Wuhan. If the sources of the infections are indeed certain animals sold in the market, other markets in the city may continue to pose a risk of infection. At the moment, there is no information on the source of infection or the transmission mode. As of 16 January 2020, there is no clear indication of sustained human-to-human transmission. The report of two small family clusters in Wuhan and the exposure history of the imported Japanese case (history of contact with a person with an acute, not laboratory confirmed, respiratory infection in Wuhan) suggest that person-to-person transmission may have occurred. In the absence of detailed information from the ongoing studies in China, it is impossible to quantify the potential of the 2019-nCoV for human-to-human transmission. The clinical information on confirmed 2019-nCoV cases reported so far suggests a milder disease course than that observed in SARS-CoV and MERS-CoV cases. However, in the absence of results from ongoing epidemiological investigations, it is impossible to assess whether there are population groups at higher risk of severe illness. Risk for travellers, importation and further spread in the EU Three EU airports have direct flight connections to Wuhan and there are indirect flight connections to other EU hubs. The likelihood of EU/EEA travellers becoming infected while visiting any wet or live animal markets in Wuhan is considered to be moderate, as the source of infection is unknown and could still be active. The likelihood of infection for travellers visiting Wuhan, but not visiting these markets, is considered low, because so far there is no indication of virus circulation in the community. Therefore, the likelihood of importation of cases of 2019-nCoV to the EU is considered to be low, but cannot be excluded in the current situation. The upcoming Chinese New Year celebrations at the end of January 2020 will cause an increase in the volume of travel to/from China and within China, increasing the likelihood of possible cases arriving in the EU. If a case is identified in the EU, rigorous infection prevention and control measures (IPC) should be applied. Current evidence that human-to-human transmission is limited indicates that the assessed likelihood of further spread in the community setting within the EU/EEA is very low, but the risk cannot be excluded. Risk of nosocomial transmission, infection prevention and control So far, there are no reported instances of disease transmission to healthcare workers/medical personnel in China, Japan and Thailand. Therefore, the likelihood of nosocomial transmission is considered very low, provided that appropriate IPC measures are applied [41]. Risk of transmission in airplane There are no specific guidelines for assessing the risk of 2019-nCoV transmission during a flight. Assessment should be made on a case-by-case basis. As the current level of uncertainty regarding transmission of 2019-nCoV is high, comprehensive contact tracing of confirmed cases should be considered and if this is not possible, efforts should be made to at least trace passengers seated in the same row and passengers seated two rows in front or behind the index case. In addition, ECDC will shortly be publishing an updated guide on MERS-CoV infections during a flight. https://www.ecdc.europa.eu/en/publications-data/rapid-risk-assessment-cluster-pneumonia-cases-caused-novel-coronavirus-wuhan

Most travel from China is in January because of Lunar New Year travel

Direct flights JFK & SFO Indirect flights LAX

Screening passengers on direct flights from Wuhan to begin