niman

Sequences producing significant alignments:Select:AllNone Selected:0 AlignmentsDownloadGenBankGraphicsDistance tree of resultsShow/hide columns of the table presenting sequences producing significant alignmentsSequences producing significant alignments:Select for downloading or viewing reportsDescriptionMax scoreTotal scoreQuery coverE valueIdentAccessionSelect seq gb|KU501217.1|Zika virus strain 8375 polyprotein gene, complete cds1842018420100%0.099%KU501217.1Select seq gb|KU501216.1|Zika virus strain 103344 polyprotein gene, complete cds1841718417100%0.099%KU501216.1Select seq gb|KU509998.1|Zika virus strain Haiti/1225/2014, complete genome1837518375100%0.099%KU509998.1Select seq gb|KJ776791.1|Zika virus strain H/PF/2013 polyprotein gene, complete cds1837218372100%0.099%KJ776791.1Select seq gb|KU707826.1|Zika virus isolate SSABR1, complete genome1836318363100%0.099%KU707826.1Select seq gb|KU365779.1|Zika virus strain BeH819966 polyprotein gene, complete cds1836318363100%0.099%KU365779.1Select seq gb|KU321639.1|Zika virus strain ZikaSPH2015, complete genome1836318363100%0.099%KU321639.1Select seq gb|KU926309.1|Zika virus isolate Rio-U1, complete genome1835718357100%0.099%KU926309.1Select seq gb|KU729218.1|Zika virus isolate BeH828305 polyprotein gene, complete cds1835418354100%0.099%KU729218.1Select seq gb|KU365780.1|Zika virus strain BeH815744 polyprotein gene, complete cds1834818348100%0.099%KU365780.1Select seq gb|KU365777.1|Zika virus strain BeH818995 polyprotein gene, complete cds1834518345100%0.099%KU365777.1Select seq gb|KU647676.1|Zika virus strain MRS_OPY_Martinique_PaRi_2015 polyprotein gene, complete cds1833618336100%0.099%KU647676.1Select seq gb|KU365778.1|Zika virus strain BeH819015 polyprotein gene, complete cds1833018330100%0.099%KU365778.1Select seq gb|KU312312.1|Zika virus isolate Z1106033 polyprotein gene, complete cds1833018330100%0.099%KU312312.1Select seq gb|KU729217.2|Zika virus isolate BeH823339 polyprotein gene, complete cds1832718327100%0.099%KU729217.2Select seq gb|KU497555.1|Zika virus isolate Brazil-ZKV2015, complete genome183271832799%0.099%KU497555.1Select seq gb|KU527068.1|Zika virus strain Natal RGN, complete genome1832718327100%0.099%KU527068.1Select seq gb|KU820897.1|Zika virus isolate FLR polyprotein gene, complete cds1832118321100%0.099%KU820897.1Select seq gb|KU501215.1|Zika virus strain PRVABC59, complete genome1832118321100%0.099%KU501215.1Select seq gb|KU922960.1|Zika virus isolate MEX/InDRE/Sm/2016, complete genome1831818318100%0.099%KU922960.1Select seq gb|KU926310.1|Zika virus isolate Rio-S1, complete genome1831218312100%0.099%KU926310.1Select seq gb|KU922923.1|Zika virus isolate MEX/InDRE/Lm/2016, complete genome1831218312100%0.099%KU922923.1Select seq gb|KU820898.1|Zika virus isolate GZ01 polyprotein gene, complete cds1830318303100%0.099%KU820898.1Select seq gb|KU853013.1|Zika virus isolate Dominican Republic/2016/PD2, complete genome1830318303100%0.099%KU853013.1Select seq gb|KU853012.1|Zika virus isolate Dominican Republic/2016/PD1, complete genome1830318303100%0.099%KU853012.1Select seq gb|KU740184.2|Zika virus isolate GD01 polyprotein gene, complete cds1829418294100%0.099%KU740184.2Select seq gb|KU761564.1|Zika virus isolate GDZ16001 polyprotein gene, complete cds1829418294100%0.099%KU761564.1Select seq gb|KU820899.2|Zika virus isolate ZJ03, complete genome1826718267100%0.099%KU820899.2Select seq gb|KU866423.1|Zika virus isolate Zika virus/SZ01/2016 polyprotein gene, complete cds1815918159100%0.099%KU866423.1Select seq gb|KU744693.1|Zika virus isolate VE_Ganxian, complete genome1813718137100%0.099%KU744693.1Select seq gb|KU681081.3|Zika virus isolate Zika virus/H.sapiens-tc/THA/2014/SV0127- 14, complete genome1802918029100%0.099%KU681081.3Select seq gb|JN860885.1|Zika virus isolate FSS13025 polyprotein gene, partial cds177301773099%0.098%JN860885.1Select seq gb|KF993678.1|Zika virus strain PLCal_ZV from Canada polyprotein gene, partial cds176761767698%0.099%KF993678.1Select seq gb|EU545988.1|Zika virus polyprotein gene, complete cds1756717567100%0.098%EU545988.1Select seq gb|KU681082.3|Zika virus isolate Zika virus/H.sapiens-tc/PHL/2012/CPC-0740, complete genome1742917429100%0.098%KU681082.3Select seq gb|HQ234499.1|Zika virus isolate P6-740 polyprotein gene, partial cds163971639799%0.095%HQ234499.1Select seq gb|KU720415.1|Zika virus strain MR 766 polyprotein gene, complete cds1328613286100%0.089%KU720415.1Select seq gb|HQ234498.1|Zika virus isolate MR_766 polyprotein gene, partial cds132811328199%0.089%HQ234498.1Select seq gb|KF383115.1|Zika virus strain ArB1362 polyprotein gene, complete cds1327513275100%0.089%KF383115.1Select seq gb|KF268949.1|Zika virus isolate ARB15076 polyprotein gene, complete cds1327013270100%0.089%KF268949.1Select seq gb|KF268948.1|Zika virus isolate ARB13565 polyprotein gene, complete cds1327013270100%0.089%KF268948.1Select seq dbj|LC002520.1|Zika virus genomic RNA, complete genome, strain: MR766-NIID1326313263100%0.089%LC002520.1Select seq gb|KF268950.1|Zika virus isolate ARB7701 polyprotein gene, complete cds1326313263100%0.089%KF268950.1Select seq gb|KF383119.1|Zika virus strain ArD158084 polyprotein gene, complete cds1325913259100%0.089%KF383119.1Select seq gb|DQ859059.1|Zika virus strain MR 766 polyprotein gene, complete cds1324313243100%0.089%DQ859059.1Select seq gb|KF383116.1|Zika virus strain ArD7117 polyprotein gene, complete cds1323013230100%0.089%KF383116.1Select seq gb|HQ234501.1|Zika virus isolate ArD_41519 polyprotein gene, partial cds132141321499%0.089%HQ234501.1Select seq gb|AY632535.2|Zika virus strain MR 766, complete genome1320513205100%0.089%AY632535.2Select seq gb|KF383117.1|Zika virus strain ArD128000 polyprotein gene, complete cds1316013160100%0.088%KF383117.1Select seq gb|HQ234500.1|Zika virus isolate IbH_30656 polyprotein gene, partial cds131441314499%0.088%HQ234500.1Select seq gb|KF383118.1|Zika virus strain ArD157995 polyprotein gene, complete cds1294513013100%0.088%KF383118.1Select seq gb|KF383121.1|Zika virus strain ArD158095 polyprotein gene, partial cds128551285597%0.089%KF383121.1Select seq gb|KF383120.1|Zika virus strain ArD142623 nonfunctional polyprotein gene, partial sequence108771087797%0.084%KF383120.1Select seq gb|KU312314.1|Zika virus isolate Z1106031 polyprotein gene, partial cds4967496727%0.099%KU312314.1Select seq gb|KU312313.1|Zika virus isolate Z1106032 polyprotein gene, partial cds4940494027%0.099%KU312313.1Select seq gb|KU646828.1|Zika virus isolate Si322 polyprotein gene, partial cds4655465525%0.099%KU646828.1Select seq gb|KU646827.1|Zika virus isolate Si323 polyprotein gene, partial cds4646464625%0.099%KU646827.1Select seq gb|KU312315.1|Zika virus isolate Z1106027 polyprotein gene, partial cds3440344018%0.099%KU312315.1Select seq gb|KU740199.1|Zika virus isolate VE_Ganxian2016 polyprotein gene, partial cds3214321417%0.099%KU740199.1Select seq gb|DQ859064.1|Spondweni virus strain SM-6 V-1 polyprotein gene, complete cds2879420695%0.071%DQ859064.1Select seq gb|KJ634273.1|Zika virus strain CK-ISL 2014 E protein (E) gene, partial cds2695269514%0.099%KJ634273.1Select seq gb|KU686218.1|Zika virus isolate MEX/InDRE/14/2015 polyprotein gene, partial cds2042204211%0.099%KU686218.1Select seq gb|KU179098.1|Zika virus isolate JMB-185 nonstructural protein 5 gene, partial cds2021202111%0.099%KU179098.1Select seq gb|KM078936.1|Zika virus strain CHI1410214 NS5 protein gene, partial cds175217529%0.099%KM078936.1Select seq gb|KM078961.1|Zika virus strain CHI2612114 NS5 protein gene, partial cds174817489%0.099%KM078961.1Select seq gb|KM078930.1|Zika virus strain CHI2283714 NS5 protein gene, partial cds174617469%0.099%KM078930.1Select seq gb|KM078971.1|Zika virus strain CHI2613014 NS5 protein gene, partial cds174517459%0.099%KM078971.1Select seq gb|KM078970.1|Zika virus strain CHI2490414 NS5 protein gene, partial cds174517459%0.099%KM078970.1Select seq gb|KM078933.1|Zika virus strain CHI1058514 NS5 protein gene, partial cds174517459%0.099%KM078933.1Select seq gb|KM078929.1|Zika virus strain CHI1805214 NS5 protein gene, partial cds174317439%0.099%KM078929.1Select seq gb|KJ873160.1|Zika virus isolate NC14-03042014-3481 nonstructural protein 5 gene, partial cds160216028%0.099%KJ873160.1Select seq gb|KJ873161.1|Zika virus isolate NC14-02042014-3220 nonstructural protein 5 gene, partial cds142014207%0.099%KJ873161.1Select seq gb|KM851039.1|Zika virus strain SV0127/14 nonstructural protein 5 gene, partial cds138813887%0.099%KM851039.1Select seq gb|KM851038.1|Zika virus strain CPC-0740 nonstructural protein 5 gene, partial cds135213527%0.098%KM851038.1Select seq gb|KU556802.1|Zika virus isolate MEX/InDRE/14/2015 NS5 protein gene, partial cds134613467%0.099%KU556802.1Select seq gb|AF013415.1|Zika virus strain MR-766 NS5 protein (NS5) gene, partial cds1306130610%0.088%AF013415.1Select seq gb|KU232300.1|Zika virus isolate 067ZV_PEBR15 NS5 protein gene, partial cds124012406%0.099%KU232300.1Select seq gb|KT200609.1|Zika virus isolate BR/949/15 NS5 gene, partial cds124012406%0.099%KT200609.1Select seq gb|KU232290.1|Zika virus isolate 036ZV_PEBR15 NS5 protein gene, partial cds123112316%0.099%KU232290.1Select seq gb|KU232297.1|Zika virus isolate 049ZV_PEBR15 NS5 protein gene, partial cds122912296%0.099%KU232297.1Select seq gb|KU232294.1|Zika virus isolate 061ZV_PEBR15 NS5 protein gene, partial cds122012206%0.099%KU232294.1Select seq gb|KU232292.1|Zika virus isolate 054ZV_PEBR15 NS5 protein gene, partial cds121812186%0.099%KU232292.1Select seq gb|KU232298.1|Zika virus isolate 050ZV_PEBR15 NS5 protein gene, partial cds121412146%0.099%KU232298.1Select seq gb|KU232296.1|Zika virus isolate 045ZV_PEBR15 NS5 protein gene, partial cds121112116%0.099%KU232296.1Select seq gb|KU232293.1|Zika virus isolate 057ZV_PEBR15 NS5 protein gene, partial cds121112116%0.099%KU232293.1Select seq gb|KU232295.1|Zika virus isolate 068ZV_PEBR15 NS5 protein gene, partial cds120512056%0.099%KU232295.1Select seq gb|KU232288.1|Zika virus isolate 001ZV_PEBR15 NS5 protein gene, partial cds119511956%0.099%KU232288.1Select seq gb|KU232289.1|Zika virus isolate 020ZV_PEBR15 NS5 protein gene, partial cds119111916%0.099%KU232289.1Select seq gb|KU232299.1|Zika virus isolate 015ZV_PEBR15 NS5 protein gene, partial cds118711876%0.099%KU232299.1Select seq gb|KU232291.1|Zika virus isolate 051ZV_PEBR15 NS5 protein gene, partial cds118611866%0.099%KU232291.1Select seq gb|KU758878.1|Zika virus polyprotein gene, partial cds113011306%0.098%KU758878.1Select seq gb|KF270886.1|Zika virus strain CCB-870 envelope glycoprotein gene, partial cds106810688%0.088%KF270886.1Select seq gb|KU867812.1|Zika virus isolate Jiangxi.CHN/01/2016 nonstructural protein 5 gene, partial cds101810185%0.0100%KU867812.1Select seq gb|AF372422.1|AF372422Zika virus envelope protein (E) gene, partial cds101110118%0.086%AF372422.1Select seq gb|KF270887.1|Zika virus strain CCB-870 NS3 protein gene, partial cds9919917%0.088%KF270887.1Select seq gb|KF383022.1|Zika virus strain ArD127988 envelope protein gene, partial cds9759757%0.089%KF383022.1Select seq gb|EF158064.1|St. Louis encephalitis virus strain GML 902612 polyprotein gene, partial cds975197764%0.070%EF158064.1Select seq gb|KF383026.1|Zika virus strain ArD127994 envelope protein gene, partial cds9719717%0.089%KF383026.1Select seq gb|EU303241.1|Zika virus note MR766 (p4 15/9/76) nonstructural protein 5 (NS5) gene, partial cds9719717%0.088%EU303241.1Select seq gb|KF383032.1|Zika virus strain ArD30101 envelope protein gene, partial cds9629627%0.088%KF383032.1Select seq gb|KF383037.1|Zika virus strain ArA506 envelope protein gene, partial cds9579577%0.088%KF383037.1Select seq gb|KF383034.1|Zika virus strain ArD30156 envelope protein gene, partial cds9579577%0.088%KF383034.1Select seq gb|KF383029.1|Zika virus strain ArD165522 envelope protein gene, partial cds9579577%0.088%KF383029.1Select seq gb|KF383033.1|Zika virus strain AnD30332 envelope protein gene, partial cds9539537%0.088%KF383033.1Select seq gb|KF383036.1|Zika virus strain ArA975 envelope protein gene, partial cds9519517%0.088%KF383036.1Select seq gb|JX041632.1|West Nile virus strain Ig2266, complete genome939178958%0.069%JX041632.1Select seq gb|KF383028.1|Zika virus strain ArD165531 envelope protein gene, partial cds9359357%0.088%KF383028.1Select seq gb|KF383039.1|Zika virus strain HD78788 envelope protein gene, partial cds9339337%0.088%KF383039.1Select seq gb|GQ851605.1|West Nile virus strain G16146 polyprotein gene, complete cds931184654%0.069%GQ851605.1Select seq gb|KF383031.1|Zika virus strain ArD9957 envelope protein gene, partial cds9309307%0.087%KF383031.1Select seq gb|KF383038.1|Zika virus strain ArA986 envelope protein gene, partial cds9249247%0.087%KF383038.1Select seq gb|KF383046.1|Zika virus strain ArA982 envelope protein gene, partial cds9159157%0.087%KF383046.1Select seq gb|KT823415.1|St. Louis encephalitis virus strain RT 121B polyprotein gene, complete cds908190265%0.069%KT823415.1Select seq gb|FJ753286.2|St. Louis encephalitis virus strain CbaAr-4005, complete genome908192365%0.069%FJ753286.2Select seq gb|KF383045.1|Zika virus strain ArA27106 envelope protein gene, partial cds9029027%0.087%KF383045.1Select seq gb|KF383103.1|Zika virus strain ArA986 nonstructural protein 5 gene, partial cds8978976%0.088%KF383103.1Select seq gb|KF383086.1|Zika virus strain ArA975 nonstructural protein 5 gene, partial cds8978976%0.088%KF383086.1Select seq gb|KF383043.1|Zika virus strain ArA27443 envelope protein gene, partial cds8978977%0.087%KF383043.1Select seq gb|KF383035.1|Zika virus strain MR1429 envelope protein gene, partial cds8978977%0.086%KF383035.1Select seq gb|KF383041.1|Zika virus strain ArA27290 envelope protein gene, partial cds8938937%0.086%KF383041.1Select seq gb|KF383042.1|Zika virus strain ArA27096 envelope protein gene, partial cds8888887%0.086%KF383042.1Select seq gb|KF383104.1|Zika virus strain ArA982 nonstructural protein 5 gene, partial cds8658656%0.087%KF383104.1Select seq gb|KF383085.1|Zika virus strain ArD9957 nonstructural protein 5 gene, partial cds8658656%0.087%KF383085.1Select seq gb|KF383040.1|Zika virus strain ArA27101 envelope protein gene, partial cds8638637%0.085%KF383040.1Select seq gb|KF383106.1|Zika virus strain ArA27443 nonstructural protein 5 gene, partial cds8618616%0.087%KF383106.1Select seq gb|KF383114.1|Zika virus strain AnD30332 nonstructural protein 5 gene, partial cds8568566%0.087%KF383114.1Select seq gb|KF383107.1|Zika virus strain ArA27407 nonstructural protein 5 gene, partial cds8568566%0.087%KF383107.1Select seq gb|KF383088.1|Zika virus strain ArD30101 nonstructural protein 5 gene, partial cds8568566%0.087%KF383088.1Select seq gb|KF383087.1|Zika virus strain ArD30156 nonstructural protein 5 gene, partial cds8528526%0.087%KF383087.1Select seq gb|KF383089.1|Zika virus strain ArD165531 nonstructural protein 5 gene, partial cds8388386%0.086%KF383089.1Select seq gb|KF383101.1|Zika virus strain ArD127710 nonstructural protein 5 gene, partial cds8348346%0.086%KF383101.1Select seq gb|KF383097.1|Zika virus strain ArD127994 nonstructural protein 5 gene, partial cds8348346%0.086%KF383097.1Select seq gb|KF383099.1|Zika virus strain ArD127987 nonstructural protein 5 gene, partial cds8298296%0.086%KF383099.1Select seq dbj|AB908162.1|Zika virus gene for polyprotein, partial cds, strain: ZIKV Hu/Tahiti/01u/2014NIID8298294%0.099%AB908162.1Select seq gb|KF383098.1|Zika virus strain ArD127988 nonstructural protein 5 gene, partial cds8258256%0.086%KF383098.1Select seq gb|KU872850.1|Zika virus isolate Dominican Rep-Rus-2016, NS2 partial cds8148144%0.099%KU872850.1

LOCUS KU870645 10798 bp RNA linear VRL 22-MAR-2016 DEFINITION Zika virus isolate FB-GWUH-2016, complete genome. ACCESSION KU870645 VERSION KU870645.1 GI:1006593136 KEYWORDS . SOURCE Zika virus ORGANISM Zika virus Viruses; ssRNA viruses; ssRNA positive-strand viruses, no DNA stage; Flaviviridae; Flavivirus. REFERENCE 1 (bases 1 to 10798) AUTHORS Driggers,R.W., Ho,C.-Y., Korhonen,E.M., Kuivanen,S., Jaaskelainen,A.J., Smura,T., Rosenberg,A., Hill,A., DeBiasi,R., Vezina,G., Timofeev,J., Rodriguez,F.J., Levanov,L., Razak,J., Iyengar,P., Hennenfent,A., Kennedy,R., Lanciotti,R., du Plessis,A. and Vapalahti,O. TITLE Zika virus infection with prolonged maternal viremia and fetal brain abnormalities JOURNAL Unpublished REFERENCE 2 (bases 1 to 10798) AUTHORS Smura,T., Korhonen,E., Kuivanen,S. and Vapalahti,O. TITLE Direct Submission JOURNAL Submitted (05-MAR-2016) Department of Virology, University of Helsinki, Haartmaninkatu 3, Helsinki 00280, Finland FEATURES Location/Qualifiers source 1..10798 /organism="Zika virus" /mol_type="genomic RNA" /isolate="FB-GWUH-2016" /isolation_source="fetal brain" /host="Homo sapiens" /db_xref="taxon:64320" /country="USA" /collection_date="02-Feb-2016" /note="putative country of infection: Guatemala; passage details: SK-N-SH"http://www.ncbi.nlm.nih.gov/nuccore/KU870645

Although confirmation of over 300 US Zika cases in 2015/2016 have been reported, including 278 on the CDC update page of confirmations in the US, no sequences have been released from US residents collected in 2015/2016. Today a full sequence was accessible at Genbank. The name of the sequence, FB-GWUH/2016 suggests it was collected on February 2, 2016 from a fetal brain at George Washington University Hospital, which is reflected in the "USA" origin from "fetal brain", as cited on the characterization page. Moreover, the characterization sheet indicates that the patient was thought to have been infected in Guatemala, which is fully supported by the relatedness to the two Zika sequences at Genbank from Guatemala. This data matches "Patient B" described in the CDC MMWR on pregnant Zika confirmed US residents, as well as a media report describing a Washington DC resident infected in Central America, who elected to terminate her pregnancy after Zika was confirmed in amniotic fluid and sonograms and MRI confirmed severe microcephaly in the fetus. Although the CDC MMWR described the radiological confirmation of microcephaly and the patient was Zika confirmed by PCR,this case has not been cited in the WHO SitRep on confirmed microcephaly cases (the only US case is the full term infant in Hawaii).

DoH says only one confirmation. Landing page modified for future reference,

Sequence map update https://www.google.com/maps/d/u/0/edit?mid=zv94AJqgUct4.kI8kcFySb4J0&hl=en

Sequences producing significant alignments:Select:AllNone Selected:0 AlignmentsDownloadGenBankGraphicsDistance tree of resultsShow/hide columns of the table presenting sequences producing significant alignmentsSequences producing significant alignments:Select for downloading or viewing reportsDescriptionMax scoreTotal scoreQuery coverE valueIdentAccessionSelect seq gb|KU501217.1|Zika virus strain 8375 polyprotein gene, complete cds1842018420100%0.099%KU501217.1Select seq gb|KU501216.1|Zika virus strain 103344 polyprotein gene, complete cds1841718417100%0.099%KU501216.1Select seq gb|KU509998.1|Zika virus strain Haiti/1225/2014, complete genome1837518375100%0.099%KU509998.1Select seq gb|KJ776791.1|Zika virus strain H/PF/2013 polyprotein gene, complete cds1837218372100%0.099%KJ776791.1Select seq gb|KU707826.1|Zika virus isolate SSABR1, complete genome1836318363100%0.099%KU707826.1Select seq gb|KU365779.1|Zika virus strain BeH819966 polyprotein gene, complete cds1836318363100%0.099%KU365779.1Select seq gb|KU321639.1|Zika virus strain ZikaSPH2015, complete genome1836318363100%0.099%KU321639.1Select seq gb|KU926309.1|Zika virus isolate Rio-U1, complete genome1835718357100%0.099%KU926309.1Select seq gb|KU729218.1|Zika virus isolate BeH828305 polyprotein gene, complete cds1835418354100%0.099%KU729218.1Select seq gb|KU365780.1|Zika virus strain BeH815744 polyprotein gene, complete cds1834818348100%0.099%KU365780.1Select seq gb|KU365777.1|Zika virus strain BeH818995 polyprotein gene, complete cds1834518345100%0.099%KU365777.1Select seq gb|KU647676.1|Zika virus strain MRS_OPY_Martinique_PaRi_2015 polyprotein gene, complete cds1833618336100%0.099%KU647676.1Select seq gb|KU365778.1|Zika virus strain BeH819015 polyprotein gene, complete cds1833018330100%0.099%KU365778.1Select seq gb|KU312312.1|Zika virus isolate Z1106033 polyprotein gene, complete cds1833018330100%0.099%KU312312.1Select seq gb|KU729217.2|Zika virus isolate BeH823339 polyprotein gene, complete cds1832718327100%0.099%KU729217.2Select seq gb|KU497555.1|Zika virus isolate Brazil-ZKV2015, complete genome183271832799%0.099%KU497555.1Select seq gb|KU527068.1|Zika virus strain Natal RGN, complete genome1832718327100%0.099%KU527068.1Select seq gb|KU820897.1|Zika virus isolate FLR polyprotein gene, complete cds1832118321100%0.099%KU820897.1Select seq gb|KU501215.1|Zika virus strain PRVABC59, complete genome1832118321100%0.099%KU501215.1Select seq gb|KU922960.1|Zika virus isolate MEX/InDRE/Sm/2016, complete genome1831818318100%0.099%KU922960.1Select seq gb|KU926310.1|Zika virus isolate Rio-S1, complete genome1831218312100%0.099%KU926310.1Select seq gb|KU922923.1|Zika virus isolate MEX/InDRE/Lm/2016, complete genome1831218312100%0.099%KU922923.1Select seq gb|KU820898.1|Zika virus isolate GZ01 polyprotein gene, complete cds1830318303100%0.099%KU820898.1Select seq gb|KU853013.1|Zika virus isolate Dominican Republic/2016/PD2, complete genome1830318303100%0.099%KU853013.1Select seq gb|KU853012.1|Zika virus isolate Dominican Republic/2016/PD1, complete genome1830318303100%0.099%KU853012.1Select seq gb|KU740184.2|Zika virus isolate GD01 polyprotein gene, complete cds1829418294100%0.099%KU740184.2Select seq gb|KU761564.1|Zika virus isolate GDZ16001 polyprotein gene, complete cds1829418294100%0.099%KU761564.1Select seq gb|KU820899.2|Zika virus isolate ZJ03, complete genome1826718267100%0.099%KU820899.2Select seq gb|KU866423.1|Zika virus isolate Zika virus/SZ01/2016 polyprotein gene, complete cds1815918159100%0.099%KU866423.1Select seq gb|KU744693.1|Zika virus isolate VE_Ganxian, complete genome1813718137100%0.099%KU744693.1Select seq gb|KU681081.3|Zika virus isolate Zika virus/H.sapiens-tc/THA/2014/SV0127- 14, complete genome1802918029100%0.099%KU681081.3Select seq gb|JN860885.1|Zika virus isolate FSS13025 polyprotein gene, partial cds177301773099%0.098%JN860885.1Select seq gb|KF993678.1|Zika virus strain PLCal_ZV from Canada polyprotein gene, partial cds176761767698%0.099%KF993678.1Select seq gb|EU545988.1|Zika virus polyprotein gene, complete cds1756717567100%0.098%EU545988.1Select seq gb|KU681082.3|Zika virus isolate Zika virus/H.sapiens-tc/PHL/2012/CPC-0740, complete genome1742917429100%0.098%KU681082.3Select seq gb|HQ234499.1|Zika virus isolate P6-740 polyprotein gene, partial cds163971639799%0.095%HQ234499.1Select seq gb|KU720415.1|Zika virus strain MR 766 polyprotein gene, complete cds1328613286100%0.089%KU720415.1Select seq gb|HQ234498.1|Zika virus isolate MR_766 polyprotein gene, partial cds132811328199%0.089%HQ234498.1Select seq gb|KF383115.1|Zika virus strain ArB1362 polyprotein gene, complete cds1327513275100%0.089%KF383115.1Select seq gb|KF268949.1|Zika virus isolate ARB15076 polyprotein gene, complete cds1327013270100%0.089%KF268949.1Select seq gb|KF268948.1|Zika virus isolate ARB13565 polyprotein gene, complete cds1327013270100%0.089%KF268948.1Select seq dbj|LC002520.1|Zika virus genomic RNA, complete genome, strain: MR766-NIID1326313263100%0.089%LC002520.1Select seq gb|KF268950.1|Zika virus isolate ARB7701 polyprotein gene, complete cds1326313263100%0.089%KF268950.1Select seq gb|KF383119.1|Zika virus strain ArD158084 polyprotein gene, complete cds1325913259100%0.089%KF383119.1Select seq gb|DQ859059.1|Zika virus strain MR 766 polyprotein gene, complete cds1324313243100%0.089%DQ859059.1Select seq gb|KF383116.1|Zika virus strain ArD7117 polyprotein gene, complete cds1323013230100%0.089%KF383116.1Select seq gb|HQ234501.1|Zika virus isolate ArD_41519 polyprotein gene, partial cds132141321499%0.089%HQ234501.1Select seq gb|AY632535.2|Zika virus strain MR 766, complete genome1320513205100%0.089%AY632535.2Select seq gb|KF383117.1|Zika virus strain ArD128000 polyprotein gene, complete cds1316013160100%0.088%KF383117.1Select seq gb|HQ234500.1|Zika virus isolate IbH_30656 polyprotein gene, partial cds131441314499%0.088%HQ234500.1Select seq gb|KF383118.1|Zika virus strain ArD157995 polyprotein gene, complete cds1294513013100%0.088%KF383118.1Select seq gb|KF383121.1|Zika virus strain ArD158095 polyprotein gene, partial cds128551285597%0.089%KF383121.1Select seq gb|KF383120.1|Zika virus strain ArD142623 nonfunctional polyprotein gene, partial sequence108771087797%0.084%KF383120.1Select seq gb|KU312314.1|Zika virus isolate Z1106031 polyprotein gene, partial cds4967496727%0.099%KU312314.1Select seq gb|KU312313.1|Zika virus isolate Z1106032 polyprotein gene, partial cds4940494027%0.099%KU312313.1Select seq gb|KU646828.1|Zika virus isolate Si322 polyprotein gene, partial cds4655465525%0.099%KU646828.1Select seq gb|KU646827.1|Zika virus isolate Si323 polyprotein gene, partial cds4646464625%0.099%KU646827.1Select seq gb|KU312315.1|Zika virus isolate Z1106027 polyprotein gene, partial cds3440344018%0.099%KU312315.1Select seq gb|KU740199.1|Zika virus isolate VE_Ganxian2016 polyprotein gene, partial cds3214321417%0.099%KU740199.1Select seq gb|DQ859064.1|Spondweni virus strain SM-6 V-1 polyprotein gene, complete cds2879420695%0.071%DQ859064.1Select seq gb|KJ634273.1|Zika virus strain CK-ISL 2014 E protein (E) gene, partial cds2695269514%0.099%KJ634273.1Select seq gb|KU686218.1|Zika virus isolate MEX/InDRE/14/2015 polyprotein gene, partial cds2042204211%0.099%KU686218.1Select seq gb|KU179098.1|Zika virus isolate JMB-185 nonstructural protein 5 gene, partial cds2021202111%0.099%KU179098.1Select seq gb|KM078936.1|Zika virus strain CHI1410214 NS5 protein gene, partial cds175217529%0.099%KM078936.1Select seq gb|KM078961.1|Zika virus strain CHI2612114 NS5 protein gene, partial cds174817489%0.099%KM078961.1Select seq gb|KM078930.1|Zika virus strain CHI2283714 NS5 protein gene, partial cds174617469%0.099%KM078930.1Select seq gb|KM078971.1|Zika virus strain CHI2613014 NS5 protein gene, partial cds174517459%0.099%KM078971.1Select seq gb|KM078970.1|Zika virus strain CHI2490414 NS5 protein gene, partial cds174517459%0.099%KM078970.1Select seq gb|KM078933.1|Zika virus strain CHI1058514 NS5 protein gene, partial cds174517459%0.099%KM078933.1Select seq gb|KM078929.1|Zika virus strain CHI1805214 NS5 protein gene, partial cds174317439%0.099%KM078929.1Select seq gb|KJ873160.1|Zika virus isolate NC14-03042014-3481 nonstructural protein 5 gene, partial cds160216028%0.099%KJ873160.1Select seq gb|KJ873161.1|Zika virus isolate NC14-02042014-3220 nonstructural protein 5 gene, partial cds142014207%0.099%KJ873161.1Select seq gb|KM851039.1|Zika virus strain SV0127/14 nonstructural protein 5 gene, partial cds138813887%0.099%KM851039.1Select seq gb|KM851038.1|Zika virus strain CPC-0740 nonstructural protein 5 gene, partial cds135213527%0.098%KM851038.1Select seq gb|KU556802.1|Zika virus isolate MEX/InDRE/14/2015 NS5 protein gene, partial cds134613467%0.099%KU556802.1Select seq gb|AF013415.1|Zika virus strain MR-766 NS5 protein (NS5) gene, partial cds1306130610%0.088%AF013415.1Select seq gb|KU232300.1|Zika virus isolate 067ZV_PEBR15 NS5 protein gene, partial cds124012406%0.099%KU232300.1Select seq gb|KT200609.1|Zika virus isolate BR/949/15 NS5 gene, partial cds124012406%0.099%KT200609.1Select seq gb|KU232290.1|Zika virus isolate 036ZV_PEBR15 NS5 protein gene, partial cds123112316%0.099%KU232290.1Select seq gb|KU232297.1|Zika virus isolate 049ZV_PEBR15 NS5 protein gene, partial cds122912296%0.099%KU232297.1Select seq gb|KU232294.1|Zika virus isolate 061ZV_PEBR15 NS5 protein gene, partial cds122012206%0.099%KU232294.1Select seq gb|KU232292.1|Zika virus isolate 054ZV_PEBR15 NS5 protein gene, partial cds121812186%0.099%KU232292.1Select seq gb|KU232298.1|Zika virus isolate 050ZV_PEBR15 NS5 protein gene, partial cds121412146%0.099%KU232298.1Select seq gb|KU232296.1|Zika virus isolate 045ZV_PEBR15 NS5 protein gene, partial cds121112116%0.099%KU232296.1Select seq gb|KU232293.1|Zika virus isolate 057ZV_PEBR15 NS5 protein gene, partial cds121112116%0.099%KU232293.1Select seq gb|KU232295.1|Zika virus isolate 068ZV_PEBR15 NS5 protein gene, partial cds120512056%0.099%KU232295.1Select seq gb|KU232288.1|Zika virus isolate 001ZV_PEBR15 NS5 protein gene, partial cds119511956%0.099%KU232288.1Select seq gb|KU232289.1|Zika virus isolate 020ZV_PEBR15 NS5 protein gene, partial cds119111916%0.099%KU232289.1Select seq gb|KU232299.1|Zika virus isolate 015ZV_PEBR15 NS5 protein gene, partial cds118711876%0.099%KU232299.1Select seq gb|KU232291.1|Zika virus isolate 051ZV_PEBR15 NS5 protein gene, partial cds118611866%0.099%KU232291.1Select seq gb|KU758878.1|Zika virus polyprotein gene, partial cds113011306%0.098%KU758878.1Select seq gb|KF270886.1|Zika virus strain CCB-870 envelope glycoprotein gene, partial cds106810688%0.088%KF270886.1Select seq gb|KU867812.1|Zika virus isolate Jiangxi.CHN/01/2016 nonstructural protein 5 gene, partial cds101810185%0.0100%KU867812.1

LOCUS KU870645 10798 bp RNA linear VRL 22-MAR-2016 DEFINITION Zika virus isolate FB-GWUH-2016, complete genome. ACCESSION KU870645 VERSION KU870645.1 GI:1006593136 KEYWORDS . SOURCE Zika virus ORGANISM Zika virus Viruses; ssRNA viruses; ssRNA positive-strand viruses, no DNA stage; Flaviviridae; Flavivirus. REFERENCE 1 (bases 1 to 10798) AUTHORS Driggers,R.W., Ho,C.-Y., Korhonen,E.M., Kuivanen,S., Jaaskelainen,A.J., Smura,T., Rosenberg,A., Hill,A., DeBiasi,R., Vezina,G., Timofeev,J., Rodriguez,F.J., Levanov,L., Razak,J., Iyengar,P., Hennenfent,A., Kennedy,R., Lanciotti,R., du Plessis,A. and Vapalahti,O. TITLE Zika virus infection with prolonged maternal viremia and fetal brain abnormalities JOURNAL Unpublished REFERENCE 2 (bases 1 to 10798) AUTHORS Smura,T., Korhonen,E., Kuivanen,S. and Vapalahti,O. TITLE Direct Submission JOURNAL Submitted (05-MAR-2016) Department of Virology, University of Helsinki, Haartmaninkatu 3, Helsinki 00280, Finland FEATURES Location/Qualifiers source 1..10798 /organism="Zika virus" /mol_type="genomic RNA" /isolate="FB-GWUH-2016" /isolation_source="fetal brain" /host="Homo sapiens" /db_xref="taxon:64320" /country="USA" /collection_date="02-Feb-2016" /note="putative country of infection: Guatemala; passage details: SK-N-SH" CDS 100..10371 /note="contains structural and non-structural proteins" /codon_start=1 /product="polyprotein" /protein_id="AMQ48986.1" /db_xref="GI:1006593137" /translation="MKNPKKKSGGFRIVNMLKRGVARVSPFGGLKRLPAGLLLGHGPI RMVLAILAFLRFTAIKPSLGLINRWGSVGKKEAMEIIKKFKKDLAAMLRIINARKEKK RRGADTSVGIVGLLLTTAMAAEVTRRGSAYYMYLDRNDAGEAISFPTTLGMNKCYIQI MDLGHMCDATMSYECPMLDEGVEPDDVDCWCNTTSTWVVYGTCHHKKGEARRSRRAVT LPSHSTRKLQTRSQTWLESREYTKHLIRVENWILRNPGFALAAAAIAWLLGSSTSQKV IYLVMILLIAPAYSIRCIGVSNRDFVEGMSGGTWVDVVLEHGGCVTVMAQDKPTVDIE LVTTTVSNMAEVRSYCYEASISDMASDSRCPTQGEAYLDKQSDTQYVCKRTLVDRGWG NGCGLFGKGSLVTCAKFACSKKMTGKSIQPENLEYRIMLSVHGSQHSGMIVNDTGHET DENRAKVEITPNSPRAEATLGGFGSLGLDCEPRTGLDFSDLYYLTMNNKHWLVHKEWF HDIPLPWHAGADTGTPHWNNKEALVEFKDAHAKRQTVVVLGSQEGAVHTALAGALEAE MDGAKGRLSSGHLKCRLKMDKLRLKGVSYSLCTAAFTFTKIPAETLHGTVTVEVQYAG TDGPCKVPAQMAVDMQTLTPVGRLITANPVITESTENSKMMLELDPPFGDSYIVIGIG EKKITHHWHRSGSTIGKAFEATVRGAKRMAVLGDTAWDFGSVGGALNSLGKGIHQIFG AAFKSLFGGMSWFSQILIGTLLMWLGLNTKNGSISLMCLALGGVLIFLSTAVSADVGC SVDFSKKETRCGTGVFVYNDVEAWRDRYKYHPDSPRRLAAAVKQAWEDGICGISSVSR MENIMWRSVEGELNAILEENGVQLTVVVGSVKNPMWRAPQRLPVPVNELPHGWKAWGK SYFVRAAKTNNSFVVDGDTLKECPLKHRAWNSFLVEDHGFGVFHTSVWLKVREDYSLE CDPAVIGTAVKGKEAVHSDLGYWIESEKNDTWRLKRAHLIEMKTCEWPQSHTLWTDGI EESDLIIPKSLAGPLSHHNTREGYRTQMKGPWHSEELEIRFEECPGTKVHVEETCGTR GPSLRSTTASGRVIEEWCCRECTMPPLSFRAKDGCWYGMEIRPRKEPESNLVRSMVTA GSTDHMDHFSLGVLVILLMVQEGLKKRMTTKIIISTSMAVLVAMILGGFSMSDLAKLA ILMGATFAEMNTGGDVAHLALIAAFKVRPALLVSFIFRANWTPRESMLLALASCLLQT AISALEGDLMVLINGFALAWLAIRAMVVPRTDNITLAILAALTPLARGTLLVAWRAGL ATCGGFMLLSLKGKGSVKKNLPFVMALGLTAVRLVDPINVVGLLLLTRSGKRSWPPSE VLTAVGLICALAGGFAKADIEMAGPVAAVGLLIVSYVVSGKSVDMYIERAGDITWEKD AEVTGNSPRLDVALDESGDFSLVEDDGPPMREIILKVVLMTICGMNPIAIPFAAGAWY VYVKTGKRSGALWDVPAPKEVKKGETTDGVYRVMTRRLLGSTQVGVGVMQEGVFHTMW HVTKGSALRSGEGRLDPYWGDVKQDLVSYCGPWKLDAAWDGHSEVQLLAVPPGERARN IQTLPGIFKTKDGDIGAVALDYPAGTSGSPILDKCGRVIGLYGNGVVIKNGSYVSAIT QGRREEETPVECFEPSMLKKKQLTVLDLHPGAGKTRRVLPEIVREAIKTRLRTVILAP TRVVAAEMEEALRGLPVRYMTTAVNVTHSGTEIVDLMCHATFTSRLLQPIRVPNYNLY IMDEAHFTDPSSIAARGYISTRVEMGEAAAIFMTATPPGTRDAFPDSNSPIMDTEVEV PERAWSSGFDWVTDHSGKTVWFVPSVRNGNEIAACLTKAGKRVIQLSRKTFETEFQKT KHQEWDFVVTTDISEMGANFKADRVIDSRRCLKPVILDGERVILAGPMPVTHASAAQR RGRIGRNPNKPGDEYLYGGGCAETDEDHAHWLEARMLLDNIYLQDGLIASLYRPEADK VAAIEGEFKLRTEQRKTFVELMKRGDLPVWLAYQVASAGITYTDRRWCFDGATNNTIL EDSVPAEVWTRHGEKRVLKPRWMDARVCSDHAALKSFKEFAAGKRGAAFGVMEALGTL PGHMTERFQEAIDNLAVLMRAETGSRPYKAAAAQLPETLETIMLLGLLGTVSLGIFFV LMRNKGIGKMGFGMVTLGASAWLMWLSEIEPARIACVLIVVFLLLVVLIPEPEKQRSP QDNQMAIIIMVAVGLLGLITANELGWLERTKSDLSHLMGRREEGATIGFSMDIDLRPA SAWAIYAALTTFITPAVQHAVTTSYNNYSLMAMATQAGVLFGMGKGMPFYAWDFGVPL LMIGCYSQLTPLTLIVAIILLVAHYMYLIPGLQAAAARAAQKRTAAGIMKNPVVDGIV VTDIDTMTIDPQVEKKMGQVLLIAVAVSSAILSRTAWGWGEAGALITAATSTLWEGSP NKYWNSSTATSLCNIFRGSYLAGASLIYTVTRNAGLVKRRGGGTGETLGEKWKARLNQ MSALEFYSYKKSGITEVCREEARRALKDGVATGGHAVSRGSAKLRWLVERGYLQPYGK VIDLGCGRGGWSYYAATIRKVQEVKGYTKGGPGHEEPVLVQSYGWNIVRLKSGVDVFH MAAEPCDTLLCDIGESSSSPEVEETRTLRVLSMVGDWLEKRPGAFCIKVLCPYTSTMM ETLERLQRRYGGGLVRVPLSRNSTHEMYWVSGAKSNTIKSVSTTSQLLLGRMDGPRRP VKYEEDVNLGSGTRAVVSCAEAPNMKIIGNRIERIRSEHAETWFFDENHPYRTWAYHG SYEAPTQGSASSLINGVVRLLSKPWDVVTGVTGIAMTDTTPYGQQRVFKEKVDTRVPD PQEGTRQVMSMVSSWLWKELGKHKRPRVCTKEEFINKVRSNAALGAIFEEEKEWKTAV EAVNDPRFWALVDKEREHHLRGECQSCVYNMMGKREKKQGEFGKAKGSRAIWYMWLGA RFLEFEALGFLNEDHWMGRENSGGGVEGLGLQRLGYVLEEMSCIPGGRMYADDTAGWD TRISRFDLENEALITNQMEKGHRALALAIIKYTYQNKVVKVLRPAEKGKTVMDIISRQ DQRGSGQVVTYALNTFTNLVVQLIRNMEAEEVLEMQDLWLLRRSEKVTNWLQSNGWDR LKRMAVSGDDCVVKPIDDRFAHALRFLNDMGKVRKDTQEWKPSTGWDNWEEVPFCSHH FNKLHLKDGRSIVVPCRHQDELIGRARVSPGAGWSIRETACLAKSYAQMWQLLYFHRR DLRLMANAICSSVPVDWVPTGRTTWSIHGKGEWMTTEDMLVVWNRVWIEENDHMEDKT PVTKWTDIPYLGKREDLWCGSLIGHRPRTTWAENIKNTVNMVRRIIGDEEKYMDYLST QVRYLGEEGSTPGVL" ORIGIN 1 ctgtgtgtga atcagactgc gacagttcga gtttgaagcg aaagctagca acagtatcaa 61 caggttttat tttggatttg gaaacgagag tttctggtca tgaaaaaccc aaaaaagaaa 121 tccggaggat tccggattgt caatatgcta aaacgcggag tagcccgtgt gagccccttt 181 gggggcttga agaggctgcc agccggactt ctgctgggtc atgggcccat caggatggtc 241 ttggcgattc tagccttttt gagattcacg gcaatcaagc catcactggg tctcatcaat 301 agatggggtt cagtggggaa aaaagaggct atggaaataa taaagaagtt caagaaagat 361 ctggctgcca tgttgagaat aatcaatgct aggaaggaga agaagagacg aggcgcagat 421 actagtgtcg gaattgttgg cctcctgctg accacagcta tggcagcgga ggtcactaga 481 cgtgggagtg catactatat gtacttggac agaaacgatg ctggggaggc catatctttt 541 ccaaccacat tggggatgaa taagtgttat atacagatca tggatcttgg acacatgtgt 601 gatgccacca tgagctatga gtgccctatg ctggatgagg gggtggaacc agatgacgtc 661 gattgttggt gcaacacgac gtcaacttgg gttgtgtacg gaacctgcca tcacaaaaaa 721 ggtgaagcac ggagatctag aagagctgtg acgctcccct cccattccac taggaagctg 781 caaacgcggt cgcaaacctg gttggaatca agagaataca caaagcactt gattagagtc 841 gaaaattgga tactcaggaa ccctggcttc gcgttagcag cagctgccat cgcttggctt 901 ttgggaagct caacgagcca aaaagtcata tatttggtca tgatactgct gattgccccg 961 gcatacagca tcaggtgcat aggagtcagc aatagggact ttgtggaagg tatgtcaggt 1021 gggacttggg ttgatgttgt cttggaacat ggaggttgtg tcaccgtaat ggcacaggac 1081 aaaccgactg tcgacataga gctggttaca acaacagtca gcaacatggc ggaggtaaga 1141 tcctactgct atgaggcatc aatatcagac atggcttcgg acagccgctg cccaacacaa 1201 ggtgaagcct accttgacaa gcaatcagac actcaatatg tctgcaaaag aacgttagtg 1261 gacagaggct ggggaaatgg atgtggactt tttggcaaag ggagcctggt gacatgcgct 1321 aagtttgcat gctccaagaa aatgaccggg aagagcatcc agccagagaa tctggagtac 1381 cggataatgc tgtcagttca tggctcccag cacagtggga tgatcgttaa tgacacagga 1441 catgaaactg atgagaatag agcgaaggtt gagataacgc ccaattcacc aagagccgaa 1501 gccaccctgg ggggttttgg aagcctagga cttgattgtg aaccgaggac aggccttgac 1561 ttttcagatt tgtattactt gactatgaat aacaagcact ggttggttca caaggagtgg 1621 ttccacgaca ttccattacc ttggcacgct ggggcagaca ccggaactcc acactggaac 1681 aacaaagaag cactggtaga gttcaaggac gcacatgcca aaaggcaaac tgtcgtggtt 1741 ctagggagtc aagaaggagc agttcacacg gcccttgctg gagctctgga ggctgagatg 1801 gatggtgcaa agggaaggct gtcctctggc cacttgaaat gtcgcctgaa aatggataaa 1861 ctcagattga agggcgtgtc atactccttg tgtaccgcag cgttcacatt caccaagatc 1921 ccggctgaaa cactgcacgg gacagtcaca gtggaggtac agtacgcagg gacagatgga 1981 ccttgcaagg ttccagctca gatggcggtg gacatgcaaa ctctgacccc agttgggagg 2041 ttgataaccg ctaaccccgt aatcactgaa agcactgaga actctaagat gatgctggaa 2101 cttgatccac catttgggga ctcttacatt gtcataggaa tcggggagaa gaagatcacc 2161 caccactggc acaggagtgg cagcaccatt ggaaaagcat ttgaagccac tgtgagaggt 2221 gccaagagaa tggcagtctt gggagacaca gcctgggact ttggatcagt tggaggcgct 2281 ctcaactcat tgggcaaggg catccatcaa atttttggag cagctttcaa atcattgttt 2341 ggaggaatgt cctggttctc acaaattctc attggaacgt tgctgatgtg gttgggtctg 2401 aacacaaaga atggatctat ttcccttatg tgcttggcct tagggggagt gttgatcttc 2461 ttatccacag ccgtctctgc tgatgtgggg tgctcggtgg acttctcaaa gaaggagacg 2521 agatgcggta caggggtgtt cgtctataac gacgttgaag cctggaggga caggtacaag 2581 taccatcctg actccccccg tagattggca gcagcagtca agcaagcctg ggaagatggt 2641 atctgcggga tctcctctgt ttcaagaatg gaaaacatca tgtggagatc agtagaaggg 2701 gagctcaacg caatcctgga agagaatgga gttcaactga cggtcgttgt gggatctgta 2761 aaaaacccca tgtggagagc tccacagaga ttgcccgtgc ctgtgaacga gctgccccac 2821 ggctggaagg cttgggggaa atcgtacttc gtcagagcag caaagacaaa taacagcttt 2881 gtcgtggatg gtgacacact gaaggaatgc ccactcaaac atagagcatg gaacagcttt 2941 cttgtggagg atcatgggtt cggggtattt cacactagtg tctggctcaa ggttagagaa 3001 gattattcat tagagtgtga tccagccgtt attggaacag ctgttaaggg aaaggaggct 3061 gtacacagtg atctaggcta ctggattgag agtgagaaga atgacacatg gaggctgaag 3121 agggcccatc tgatcgagat gaaaacatgt gaatggccac agtcccacac attgtggaca 3181 gatggaatag aagagagtga tctgatcata cccaagtctt tagctgggcc actcagccat 3241 cacaatacca gagagggcta caggacccaa atgaaagggc catggcacag tgaagagctt 3301 gaaattcggt ttgaggaatg cccaggcact aaggtccacg tggaggaaac atgtggaaca 3361 agaggaccat ctctgagatc aaccactgca agcggaaggg tgatcgagga atggtgctgc 3421 agggagtgca caatgccccc actgtcgttc cgggctaaag atggctgttg gtatggaatg 3481 gagataaggc ccaggaaaga accagaaagc aacttagtaa ggtcaatggt gactgcagga 3541 tcaactgatc acatggatca cttctccctt ggagtgcttg tgattctgct catggtgcag 3601 gaagggctaa agaagagaat gaccacaaag atcatcataa gcacatcaat ggcagtgctg 3661 gtagctatga tcctgggagg attttcaatg agtgacctgg ctaagcttgc aattttgatg 3721 ggtgccacct tcgcggaaat gaacactgga ggagatgtag ctcatctggc gctgatagcg 3781 gcattcaaag tcagaccagc gttgctggta tctttcatct tcagagctaa ttggacaccc 3841 cgtgaaagca tgctactggc cttggcctcg tgtcttttgc aaactgcgat ctccgccttg 3901 gaaggcgacc tgatggttct catcaatggt tttgctttgg cctggttggc aatacgagcg 3961 atggttgttc cacgcactga taacatcacc ttggcaatcc tggctgctct gacaccactg 4021 gcccggggca cactgcttgt ggcgtggaga gcaggccttg ctacttgcgg ggggtttatg 4081 ctcctctctc tgaagggaaa aggcagtgtg aagaagaact taccatttgt catggccctg 4141 ggactaaccg ctgtgaggct ggtcgacccc atcaacgtgg tgggactgct gttgctcaca 4201 aggagtggga agcggagctg gccccctagc gaagtactca cagctgttgg cctgatatgc 4261 gcattggctg gagggttcgc caaggcagat atagagatgg ctgggcccgt ggccgcggtc 4321 ggtctgctaa ttgtcagtta cgtggtctca ggaaagagtg tggacatgta cattgaaaga 4381 gcaggtgaca tcacatggga aaaagatgcg gaagtcactg gaaacagtcc ccggctcgat 4441 gtggcgctag atgagagtgg tgatttctcc ctggtggagg atgacggtcc ccccatgaga 4501 gagatcatac tcaaggtggt cctgatgacc atctgtggca tgaacccaat agccataccc 4561 tttgcagctg gagcgtggta cgtatacgtg aagactggaa aaaggagtgg tgctctatgg 4621 gatgtgcctg ctcccaagga agtaaaaaag ggggagacca cagatggagt gtacagagta 4681 atgactcgta gactgctagg ttcaacacaa gttggagtgg gagttatgca agagggggtc 4741 tttcacacta tgtggcacgt cacaaaagga tccgcactga gaagcggtga agggagactt 4801 gatccatact ggggagatgt caagcaggat ctggtgtcat actgtggtcc atggaagcta 4861 gatgccgcct gggacgggca cagcgaggtg cagctcttgg ccgtgccccc cggagagaga 4921 gcgaggaaca tccagactct gcccggaata tttaagacaa aggatgggga cattggagcg 4981 gttgcgctgg attacccagc aggaacttca ggatctccaa tcctagacaa gtgtgggaga 5041 gtgataggac tttatggcaa tggggtcgtg atcaaaaatg ggagttatgt tagtgccatc 5101 acccaaggga ggagggagga agagactcct gttgagtgct tcgagccttc gatgctgaag 5161 aagaagcagc taactgtctt agacttacat cctggagctg ggaaaaccag gagagttctt 5221 cctgaaatag tccgtgaagc cataaaaaca agactccgta ctgtgatctt agctccaacc 5281 agggttgtcg ctgctgaaat ggaggaggcc cttagagggc ttccagtgcg ttatatgaca 5341 acagcagtca atgtcaccca ctctggaaca gaaatcgtcg acttaatgtg ccatgccacc 5401 ttcacttcac gtctactaca gccaatcaga gtccccaact ataatctgta tattatggat 5461 gaggcccact tcacagatcc ctcaagtata gcagcaagag gatacatttc aacaagggtt 5521 gagatgggcg aggcggctgc catcttcatg accgccacgc caccaggaac ccgtgacgca 5581 tttccggact ccaactcacc aattatggac accgaagtgg aagtcccaga gagagcctgg 5641 agctcaggct ttgattgggt gacggatcat tctggaaaaa cagtttggtt tgttccaagc 5701 gtgaggaacg gcaatgagat cgcagcttgt ctgacaaagg ctggaaaacg ggtcatacag 5761 ctcagcagaa agacttttga gacagagttc cagaaaacaa aacatcaaga gtgggacttt 5821 gtcgtgacaa ctgacatttc agagatgggc gccaacttta aagctgaccg tgtcatagat 5881 tccaggagat gcctaaagcc ggtcatactt gatggcgaga gagtcattct ggctggaccc 5941 atgcctgtca cacatgccag cgctgctcag aggagggggc gcataggcag gaatcccaac 6001 aaacctggag atgagtatct gtatggaggt gggtgcgcag agactgacga agaccatgca 6061 cactggcttg aagcaagaat gctccttgac aatatttacc tccaagatgg cctcatagcc 6121 tcgctctatc gacctgaggc cgacaaagta gcagccattg agggagagtt caagcttagg 6181 acggagcaaa ggaagacctt tgtggaactc atgaaaagag gagatcttcc tgtttggctg 6241 gcctatcagg ttgcatctgc cggaataacc tacacagata gaagatggtg ctttgatggc 6301 gcgaccaaca acaccatact ggaagacagt gtgccggcag aggtgtggac cagacacgga 6361 gagaaaagag tgctcaaacc gaggtggatg gacgccagag tttgttcaga tcatgcggcc 6421 ctgaagtcat tcaaggagtt tgccgctggg aagagaggag cggcttttgg agtgatggaa 6481 gccctgggaa cactgccagg acacatgaca gagagattcc aggaagccat tgacaacctc 6541 gctgtgctca tgcgggcaga gactggaagc aggccttaca aagccgcggc ggcccaattg 6601 ccggagaccc tagagaccat tatgcttttg gggttgctgg gaacagtctc gctgggaatc 6661 tttttcgtct tgatgaggaa caagggcata gggaagatgg gctttggaat ggtgaccctt 6721 ggggccagtg catggctcat gtggctctcg gaaattgagc cagccagaat tgcatgtgtc 6781 ctcattgttg tgttcctatt gctggtggtg ctcatacctg agccagaaaa gcaaagatct 6841 ccccaggaca accaaatggc aatcatcatc atggtagcag taggtcttct gggcttgatt 6901 accgccaatg aactcggatg gttggagaga acaaagagtg acctaagcca tctaatggga 6961 aggagagagg agggggcaac cataggattc tcaatggaca ttgacctgcg gccagcctca 7021 gcttgggcca tctatgctgc cttgacaact ttcattaccc cagccgtcca acatgcagtg 7081 accacttcat acaacaacta ctccttaatg gcgatggcca cgcaagctgg agtgttgttt 7141 ggtatgggca aagggatgcc attctacgca tgggactttg gagtcccgct gctaatgata 7201 ggttgctact cacaattaac acccctgacc ctaatagtgg ccatcatttt gctcgtggcg 7261 cactacatgt acttgatccc agggctgcag gcagcagctg cgcgtgctgc ccagaagaga 7321 acggcagctg gcatcatgaa gaaccctgtt gtggatggaa tagtggtgac tgacattgac 7381 acaatgacaa ttgaccccca agtggagaaa aagatgggac aggtgctact catagcagta 7441 gccgtctcca gcgccatact gtcgcggacc gcctgggggt ggggggaggc tggggccctg 7501 atcacagccg caacttccac tttgtgggaa ggctctccga acaagtactg gaactcctct 7561 acagccactt cactgtgtaa catttttagg ggaagttact tggctggagc ttctctaatc 7621 tacacagtaa caagaaacgc tggcttggtc aagagacgtg ggggtggaac aggagagacc 7681 ctgggagaga aatggaaggc ccgcttgaac cagatgtcgg ccctggagtt ctactcctac 7741 aaaaagtcag gcatcaccga ggtgtgcaga gaagaggctc gccgcgccct caaggacggt 7801 gtggcaacgg gaggccatgc tgtgtcccga ggaagtgcaa agctgagatg gttggtggag 7861 cggggatacc tgcagcccta tggaaaggtc attgatcttg gatgtggcag agggggctgg 7921 agttactacg ccgccaccat ccgcaaagtt caagaagtga aaggatacac aaaaggaggc 7981 cctggtcatg aagaacccgt gttggtgcaa agctatgggt ggaacatagt ccgtcttaag 8041 agtggggtgg acgtctttca tatggcggct gagccgtgtg acacgttgct gtgtgacata 8101 ggtgagtcat catctagtcc tgaagtggaa gaaacacgga cgctcagagt cctctccatg 8161 gtgggggatt ggcttgaaaa aagaccagga gccttttgta taaaagtgtt gtgcccatac 8221 accagcacta tgatggaaac cctggagcga ctgcagcgta ggtatggggg aggactggtc 8281 agagtgccac tctcccgcaa ctctacacat gagatgtact gggtctctgg agcgaaaagc 8341 aacaccataa aaagtgtgtc caccacgagc cagctcctct tggggcgcat ggacgggcct 8401 aggaggccag tgaaatatga ggaggatgtg aatctcggct ctggcacgcg ggctgtggta 8461 agctgcgctg aagctcccaa catgaagatc attggtaacc gcattgaaag gatccgcagt 8521 gagcacgcgg aaacgtggtt ctttgacgag aaccacccat ataggacatg ggcttaccat 8581 ggaagctatg aggcccccac acaagggtca gcgtcctctc taataaacgg ggttgtcagg 8641 ctcctgtcaa aaccctggga tgtggtgact ggagtcacag gaatagctat gaccgacacc 8701 acaccgtatg gtcagcaaag agttttcaag gaaaaagtgg acactagggt gccagacccc 8761 caagaaggca ctcgtcaggt tatgagcatg gtctcttcct ggttgtggaa agagctaggc 8821 aaacacaaac ggccacgagt ctgtaccaaa gaagagttca tcaacaaggt tcgtagcaat 8881 gcagcattag gggcaatatt tgaagaggaa aaagagtgga agactgcagt ggaagctgtg 8941 aacgatccaa ggttctgggc tctagtggac aaggaaagag agcaccacct gagaggagag 9001 tgccagagtt gtgtgtacaa catgatggga aaaagagaaa agaaacaagg ggaatttgga 9061 aaggccaagg gcagccgcgc catctggtat atgtggctag gggctagatt tctagagttc 9121 gaagcccttg gattcttgaa cgaggatcac tggatgggga gagagaactc aggaggtggt 9181 gttgaagggc tgggattaca aagactcgga tatgtcctag aagagatgag ttgcatacca 9241 ggaggaagga tgtatgcaga tgacactgct ggctgggaca cccgcatcag caggtttgat 9301 ctggagaatg aagctctaat caccaaccaa atggagaaag ggcacagggc cttggcattg 9361 gccataatca agtacacata ccaaaacaaa gtggtaaagg tccttagacc agctgaaaaa 9421 gggaaaacag ttatggacat tatttcgaga caagaccaaa gggggagcgg acaagttgtc 9481 acttacgctc ttaacacatt taccaaccta gtggtgcaac tcattcggaa tatggaggct 9541 gaggaagttc tagagatgca agacttgtgg ctgctgcgga ggtcagagaa agtgaccaac 9601 tggttgcaga gcaacggatg ggataggctc aaacgaatgg cagtcagtgg agatgattgc 9661 gttgtgaagc caattgatga taggtttgca catgccctca ggttcttgaa tgatatggga 9721 aaagttagga aggacacaca agagtggaaa ccctcaactg gatgggacaa ctgggaagaa 9781 gttccgtttt gctcccacca cttcaacaag ctccatctca aggacgggag gtccattgtg 9841 gttccctgcc gccaccaaga tgaactgatt ggccgggccc gcgtctctcc aggggcggga 9901 tggagcatcc gggagactgc ttgcctagca aaatcatatg cgcaaatgtg gcagctcctt 9961 tatttccaca gaagggacct ccgactgatg gccaatgcca tttgttcatc tgtgccagtt 10021 gactgggttc caactgggag aactacctgg tcaatccatg gaaagggaga atggatgacc 10081 actgaagaca tgcttgtggt gtggaacaga gtgtggattg aggagaacga ccacatggaa 10141 gacaagaccc cagttacgaa atggacagac attccctatt tgggaaaaag ggaagacttg 10201 tggtgtggat ctctcatagg gcacagaccg cgcaccacct gggctgagaa cattaaaaac 10261 acagtcaaca tggtgcgcag gatcataggt gatgaagaaa agtacatgga ctacctatcc 10321 acccaagttc gctacttggg tgaagaaggg tctacacctg gagtgctgta agcaccaatc 10381 ttaatgttgt caggcctgct agtcagccac agcttgggga aagctgtgca gcctgtgacc 10441 cccccaggag aagctgggaa accaagccta tagtcaggcc gagaacgcca tggcacggaa 10501 gaagccatgc tgcctgtgag cccctcagag gacactgagt caaaaaaccc cacgcgcttg 10561 gaggcgcagg atgggaaaag aaggtggcga ccttccccac ccttcaatct ggggcctgaa 10621 ctggagatca gctgtggatc tccagaagag ggactagtgg ttagaggaga ccccccggaa 10681 aacgcaaaac agcatattga cgctgggaaa gaccagagac tccatgagtt tccaccacgc 10741 tggccgccag gcacagatcg ccgaatagcg gcggccggtg tggggaaatc catgcagc

University of Helsinki has release a full Zika sequence from fetal brain collected at George Washington University Hospital ex-Guatemala, FB-GWUH-2016, on Feb 2, 2016http://www.ncbi.nlm.nih.gov/nuccore/KU870645

LOCUS KU870645 10798 bp RNA linear VRL 22-MAR-2016 DEFINITION Zika virus isolate FB-GWUH-2016, complete genome. ACCESSION KU870645 VERSION KU870645.1 GI:1006593136 KEYWORDS . SOURCE Zika virus ORGANISM Zika virus Viruses; ssRNA viruses; ssRNA positive-strand viruses, no DNA stage; Flaviviridae; Flavivirus. REFERENCE 1 (bases 1 to 10798) AUTHORS Driggers,R.W., Ho,C.-Y., Korhonen,E.M., Kuivanen,S., Jaaskelainen,A.J., Smura,T., Rosenberg,A., Hill,A., DeBiasi,R., Vezina,G., Timofeev,J., Rodriguez,F.J., Levanov,L., Razak,J., Iyengar,P., Hennenfent,A., Kennedy,R., Lanciotti,R., du Plessis,A. and Vapalahti,O. TITLE Zika virus infection with prolonged maternal viremia and fetal brain abnormalities JOURNAL Unpublished REFERENCE 2 (bases 1 to 10798) AUTHORS Smura,T., Korhonen,E., Kuivanen,S. and Vapalahti,O. TITLE Direct Submission JOURNAL Submitted (05-MAR-2016) Department of Virology, University of Helsinki, Haartmaninkatu 3, Helsinki 00280, Finland FEATURES Location/Qualifiers source 1..10798 /organism="Zika virus" /mol_type="genomic RNA" /isolate="FB-GWUH-2016" /isolation_source="fetal brain" /host="Homo sapiens" /db_xref="taxon:64320" /country="USA" /collection_date="02-Feb-2016" /note="putative country of infection: Guatemala; passage details: SK-N-SH"http://www.ncbi.nlm.nih.gov/nuccore/KU870645

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Clark County resident reportedly tests positive for Zika virusBY AUBREY CLERKIN THURSDAY, MARCH 24TH 2016The Zika virus (Image courtesy: James Gathany/CDC/MGN)8 sharestweet now! MORE MEDIALAS VEGAS (KSNV News3LV) — The Southern Nevada Health District confirms that a Clark County resident has tested positive for the Zika virus. The patient who became infected is a man who recently traveled to Guatemala. "The Health District has been actively monitoring all developments related to the Zika virus and testing potential patients in accordance with CDC guidelines," said Dr. Joe Iser, Chief Health Officer for the Southern Nevada Health District. Zika virus spreads through the bite of an infected Aedes species mosquito and can be passed from person to person through sex from a man to his partners. It can also be passed from mother to her baby during pregnancy, and the possibility that it can spread through blood transfusions is being investigated. Symptoms include fever, rash, joint pain, conjunctivitis, muscle pain and headaches. Most often the virus is mild and does not require hospitalization. Four out of five people infected will not know they are carrying the virus. Currently, there is no vaccine for Zika and it can cause birth defects. For more information about the virus, travel restrictions and the impact the virus can have on a pregnancy, check out theCDC website.

The Southern Nevada Health District confirms that a Clark County resident has tested positive for the Zika virus. The patient who became infected is a man who recently traveled to Guatemala. http://mynews4.com/news/nation-world/clark-county-resident-tests-positive-for-zika-virus

January 11, 2016 – March 24, 2016 ZIKA VIRUS TESTING SUMMARY Number of people tested 111 Total # of pending results 43 Total # of negative results 66 Total # of positive results 2 ZIKA VIRUS CASE SUMMARY Female Number of Zika Virus Cases in NH 0 1 1 2 Pregnant Female Not pregnant Male TOTAL

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Zika virus infects people through the bite of a mosquito and can cause fever, rash, joint pain, and conjunctivitis. It may also be responsible for certain birth defects when pregnant women are infected with Zika. Travel-related cases of Zika virus infection have been confirmed in Mississippi. No locally-transmitted cases have been reported in the state.

Today the Mississippi State Department of Health (MSDH) announced a travel related case in Madison Co ex-Haiti.The Zika page was updated to reflect one confirmed travel cases. However, the page was then updated again to cite multiple cases in Mississippi. http://msdh.ms.gov/msdhsite/_static/14,0,399.html

Zika virus infects people through the bite of a mosquito and can cause fever, rash, joint pain, and conjunctivitis. It may also be responsible for certain birth defects when pregnant women are infected with Zika. Travel-related cases of Zika virus infection have been confirmed in Mississippi. No locally-transmitted cases have been reported in the state.

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Mississippi Health Officials Reporting First Case of Zika Virus InfectionMarch 24, 2016 JACKSON, Miss. – Today the Mississippi State Department of Health (MSDH) reports its first case of Zika virus. The case was in a Madison County resident who recently traveled to Haiti. Zika is a mosquito-borne virus that may cause devastating birth defects if contracted during pregnancy. Zika virus infection can cause a mild illness with symptoms (fever, joint pain, conjunctivitis or rash) lasting for several days to a week, but 80 percent of those infected show no symptoms at all. Death is very rare. Zika has been seen in parts of Africa, Southeast Asia, and some Pacific islands for years, but has recently been reported in approximately 30 countries, mostly in the Caribbean, Central, and South America. The Zika virus is spread through the bite of an infected mosquito. The breed of mosquito that is spreading Zika – Aedes Aegypti – has not been detected in Mississippi since the mid-eighties. The MSDH is currently conducting surveillance on all mosquito populations in the state. Pregnant women or women who may get pregnant in the near future should avoid travel to countries with Zika transmission. Pregnant women should avoid sexual contact – or only have protected sex using a condom – with any male who has recently returned from a country with Zika virus. These precautions should continue for the duration of the pregnancy. So far, six cases have been confirmed from sex between an infected male and his female partner. “Pregnant women should avoid travel to these countries,” said State Epidemiologist Dr. Thomas Dobbs. “At this time, the mosquito spreading Zika in Mexico, South America and the Caribbean is not known to be present in Mississippi.” “Three U.S. territories and 36 other states have already reported travel-associated cases,” Dobbs said. “With late spring and summer approaching, we know it is a popular time for mission trips and vacations to these areas. Please be especially mindful of protecting yourself from mosquitoes while you’re abroad. Simple steps can make a big difference.” The MSDH advises that precautions should be taken by all travelers to countries with Zika outbreaks. Precautions for travelers include basic protective measures against mosquito-borne illnesses such as using a recommended mosquito repellent that contains DEET while you are outdoors, avoiding areas where mosquitoes are prevalent, and wearing loose, light-colored clothing to cover the arms and legs when outdoors during the day or night. Travelers recently returning from countries with ongoing Zika transmission should take special precautions to avoid mosquito bites in Mississippi to avoid transmitting the virus to local mosquitoes. There are no available treatments or vaccines for Zika virus. “The MSDH is working with medical partners across the state to ensure that the most current national guidelines for preventing and testing for Zika are being followed,” said Dr. Dobbs. “The MSDH Public Health Laboratory now has the ability to test for Zika in-house to allow for rapid turnaround and high volume testing should the need arise.”

Mississippi Health Officials Reporting First Case of Zika Virus InfectionMarch 24, 2016 JACKSON, Miss. – Today the Mississippi State Department of Health (MSDH) reports its first case of Zika virus. The case was in a Madison County resident who recently traveled to Haiti. http://msdh.ms.gov/msdhsite/_static/23,17452,341.html

Zika virus infects people through the bite of a mosquito and can cause fever, rash, joint pain, and conjunctivitis. It may also be responsible for certain birth defects when pregnant women are infected with Zika. One travel-related case of Zika virus infection has been confirmed in Mississippi. No locally-transmitted cases have been reported in the state.

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Possible Zika virus case in Saskatchewan may have been sexually transmittedProvince's deputy medical health officer wouldn't say if woman in question is pregnantCBC News Posted: Mar 24, 2016 1:49 PM CT Last Updated: Mar 24, 2016 2:18 PM CT The Zika virus is usually transmitted through a specific type of mosquito. (Felipe Dana/Associated Press) 16 shares Facebook Twitter Reddit Google Share Email Related StoriesZika virus: What you need to know and how to protect yourselfZika virus link to microcephaly could take 6 months to prove: WHOInfectious Disease experts address Zika virus concernsCanadian mosquito tests for Zika virus transmission beginZika virus: women in affected countries should breastfeed, WHO recommendsZika's role in microcephaly spike to be tested by U.S.-Brazil teamZika virus test under development at University of AlbertaSaskatchewan may have Canada's first case of the Zika virus transmitted sexually. The province's deputy medical health officer updated reporters early Thursday afternoon about the case. Dr. Denise Werker said there are now two confirmed cases of the Zika virus in travellers who returned to Saskatchewan from countries that have the virus. But now, a woman who did not travel outside of the country is also suspected to have the virus. She had sex with a man who was diagnosed with Zika after travelling to an affected area, Werker said. Werker wouldn't say if the woman is pregnant. http://www.cbc.ca/news/canada/saskatchewan/zika-virus-case-in-sask-sexual-transmission-2016-1.3506451

Dr. Denise Werker said there are now two confirmed cases of the Zika virus in travellers who returned to Saskatchewan from countries that have the virus. http://www.cbc.ca/news/canada/saskatchewan/zika-virus-case-in-sask-sexual-transmission-2016-1.3506451

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