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Brief ReportSwitch to Standard View Expression Analysis Highlights AXL as a Candidate Zika Virus Entry Receptor in Neural Stem Cellshttp://www.cell.com/cell-stem-cell/fulltext/S1934-5909(16)00118-1

Zika Virus – March 30, 2016. Texas has had 27 confirmed cases of Zika virus disease. Of those, 26 were in travelers who were infected abroad and diagnosed after they returned home; one of those travelers was a pregnant woman. One case involved a Dallas County resident who had sexual contact with someone who acquired the Zika infection while traveling abroad. Case counts by county: Bexar – 3Dallas – 4Fort Bend – 2Grayson – 1Harris – 11Tarrant – 3Travis – 2Wise – 1

Allegheny County Residents Approved for Zika Testing: 50 CDC Confirmed Cases: 1(as of March 29)

http://www.achd.net/topic-zika.html

March 1, 2016 Statement from Executive Director and Chief Medical Officer Dr. Larry Wolk on Zika virus in Colorado DENVER – The Colorado Department of Public Health and Environment has confirmed two Colorado cases of Zika [Tweet this] in 2016. Both individuals had traveled to a Zika-affected country, and both have recovered. The cases were reported the week of Feb. 22. Colorado is likely to have more cases of Zika in the coming year. CDPHE will not provide information about specific cases.

https://www.colorado.gov/pacific/cdphe/news/zika

Arizona's First Zika Case Recorded in Traveler, read the news releaseTravel-associated Zika cases confirmed in Arizona: 1Arizona Arboviral Handbook for Chikungunya, Dengue, & Zika Viruses

http://www.azdhs.gov/preparedness/epidemiology-disease-control/mosquito-borne/index.php#zika-home

Published Date: 03/29/2016 22:06:46 Subject: PRO / ESP> Zika - Brazil: (03) microcephaly, increased cases update Archive Number: 20160329.4126740 ZIKA - BRAZIL: (03) microcephaly, increased incidence UPDATE ************************************************** **************** A statement from ProMED-mail http://www.promedmail.org ProMED-mail is a program of the International Society for Infectious Diseases http://www.isid.org Date: March 29, 2016 Source: Yahoo News https://es-us.noticias.yahoo.com/casos-confirmados-y-sospechosos-microcefalia-en-brasil-aumentan-213915619.html?nhp=1 [Edited by Jaime Torres] The number of confirmed and suspected cases of microcephaly in Brazil linked to Zika virus rose to 5,235 in the week to March 25 from 5,200 the previous week, the health ministry said on Tuesday. Of the total, the number of confirmed cases rose to 944 from 907 the previous week, while suspected cases fell to 4,291 from 4,293 just in the same period, according to a ministry statement. Discarded cases totaled 1,541 in the week to March 26, the statement said. Brazil considered the most cases of babies born with microcephaly, a condition in which the head and brain are smaller than normal, as linked to Zika, but has not yet been established scientifically a relationship between the virus and the congenital malformation. Reported by: Jaime R. Torres <[email protected]> - ProMED-ESP ----- ................. Jt, jg See also Zika - Brazil: (02) microcephaly, increased cases, updating 20160225.4051252 Zika - Brazil: microcephaly, increased cases, updating 20160218.4030738 .................................. http://promedmail.org/direct.php?id=20160329.4126740

Microcephaly: Ministry of Health investigates 4,291 suspected cases in the country Pernambuco follows as the state with the largest number of microcephaly notifications. Cases already completed, 944 were confirmed and 1,541 discarded.The Ministry of Health is investigating 4,291 suspected cases of microcephaly and other nervous system disorders, suggestive of congenital infection. Cases already completed, 944 were confirmed and 1,541 discarded. Since the beginning of the investigation, in October 2015, it was reported 6,776 suspected cases of microcephaly. Data from epidemiological report from the Ministry of Health are sent weekly by the state departments of Health and were closed on Saturday, March 26. Of the total confirmed cases of microcephaly, 130 tested positive for Zika. In these cases, specific laboratory test was used to Zika virus. However, the Ministry of Health points out that this figure does not represent adequately the total number of cases related to the virus. That is, the folder considers that there was infection Zika most of the mothers who had babies with a final diagnosis of microcephaly. This week, the states of Acre, Amapá, Santa Catarina and Rio Grande do Sul reported to the Ministry of Health the indigenous movement the Zika virus. Thus, all 27 Brazilian states are with Zika circulation. The 944 confirmed cases occurred in 358 municipalities located in 21 Brazilian states: Alagoas, Bahia, Ceará, Maranhão, Paraíba, Pernambuco, Piauí, Rio Grande do Norte, Sergipe, Espírito Santo, Minas Gerais, Rio de Janeiro, Amazonas, Pará , Rondônia, Distrito Federal, Goiás, Mato Grosso, Mato Grosso do Sul, Rio Grande do Sul and Parana. The 1,541 cases disposed were classified because they have normal exams, or submit microcefalias and / or changes in the central nervous system by an infectious causes. Until March 26, there were 208 deaths (fetal or neonatal) microcephaly suspects and / or amendment the central nervous system after birth or during pregnancy (miscarriage or stillbirth). Of these, 47 were confirmed to microcephaly and / or alteration of the central nervous system. Other 139 are still under investigation and 22 were discarded. The 6,776 cases reported are distributed in 1,285 municipalities, from all regions of the country. Most were registered in the Northeast (5,315 cases, which corresponds to 78%), the State of Pernambuco the Federation Unit with the largest number of cases are still being investigated (1207). Next are Bahia (676), Paraíba (412), Rio de Janeiro (322), Rio Grande do Norte (289) and Ceará (240). It should be noted that the Ministry of Health is investigating all cases of microcephaly and other central nervous system disorders, informed by the states, and the possible relationship with the Zika virus and other congenital infections.Microcephaly can be caused by various infectious agents beyond Zika as Syphilis, Toxoplasmosis, Other Infectious Agents, Rubella, Cytomegalovirus and Herpes Viral. The Ministry of Health advises pregnant women to adopt measures to reduce the presence of Aedes aegypti, with elimination of breeding sites , and protect themselves from mosquito exposure, keeping doors and closed or screened windows, wear pants and long sleeved shirts and use repellents allowed to pregnant women. Distribution of reported cases of microcephaly by UF until March 19, 2016 Regions and Federative Units Microcephaly cases and / or malformations suggestive of congenital infection Total acumulado1 of reported cases from 2015 to 2016 research Confirmed * 2.3 discarded Brazil 4,291 944 1,541 6,776 Alagoas 95 50 106 251 Bahia 676 176 120 972 Ceará 240 73 113 426 Maranhão 148 55 30 233 Paraíba 412 95 340 847 Pernambuco 1,207 273 349 1,829 Piauí 47 64 37 148 large northern river 289 83 35 407 Sergipe 162 26 14 202 Northeast 3,276 895 1,144 5,315 Holy Spirit 87 4 18 109 Minas Gerais 28 two 46 76 Rio de Janeiro 322 9 20 351 Sao Paulo 157 * 5 0 90 247 Southeast region 594 15 174 783 Acre 28 0 1 29 Amapá 0 0 0 0 Amazon 9 1 1 11 For 20 1 0 21 Rondônia 4 3 4 11 Roraima 16 0 0 16 Tocantins 115 0 17 132 North region 192 5 23 220 Federal district two 3 32 37 Goiás 80 9 30 119 Mato Grosso 113 13 71 197 Mato Grosso do Sul 4 two 11 17 Midwest region 199 27 144 370 Paraná 4 1 24 29 Santa Catarina 1 0 two 3 Rio Grande do Sul 25 1 30 56 South region 30 two 56 88 Source: . Health Departments of the States and the Federal District (updated data until 03/26/2016) * 2 present typical changes: indicative of congenital infection, such as intracranial calcifications, dilation of cerebral ventricles or posterior fossa changes and other clinical signs by any imaging method or identification of Zika virus in laboratory tests. * 3 were confirmed 130 cases by specific laboratory criteria for Zika virus (PCR and serology). * 5 As stated by the Epidemiological Surveillance Center "Prof. Alexandre Vranjac ", the State Secretary of Health of São Paulo, 157 cases are under investigation for congenital infection. Of these, 39 are possibly associated with infection by Zika virus, but have not yet been finalized investigations. http://combateaedes.saude.gov.br/noticias/505-microcefalia-ministerio-da-saude-investiga-4-291-casos-suspeitos-no-pais

Transcript CONFIRMED THE NEWS. REPORTER: HEALTH DEPARTMENT OFFICIALS JUST TOLD US THAT AN ADULT MAN HAS TESTED POSITIVE FOR ZIKA VIRUS A MAN WHO LIVES IN ALLEGHENY COUNTY, EXACTLY WHERE THEY WOULD NOT SPECIFY. THEY DID SAY THAT THIS MAN TRAVELED TO A ZIKA INFECTED COUNTRY, CAME BACK SHOWING HE WAS TESTED. IT HAS TAKEN SEVERAL WEEKS FOR THE TEST RESULTS TO COME BACK. TODAY THEY DID AND AGAIN HE IS THE FIRST CONFIRMED CASE IN VIRUS. WE ARE TOLD THAT THE MAN HAD TYPICAL SYMPTOMS WHEN HE WAS TESTED, INCLUDING RASH, FEVER, EYES. THERE IS STILL A LOT THAT WE DON'T KNOW ABOUT THE VIRUS BUT THE HEALTH DEPARTMENT SAYS THAT IT STAYS IN YOUR BLOOD FOR A WEEK AND THAT'S WHEN THE CONCERN FOR TRANSMISSION VIA A MOSQUITO BITE IS THE HIGHEST. PREGNANT WOMEN. THIS MAN INFECTED HAS BEEN TOLD TO NOT TRY TO CONCEIVE FOR AT MONTHS. >> THIS IS VERY LOW RISK RIGHT NOW TO OUR COUNTY. I THINK WHAT WE WANT TO DO MORE THAN ANYTHING IS REALLY KEEP ABREAST OF WHAT IS GOING ON MAKE OF TRAVEL. THE BIGGEST CONCERN FOR US RIGHT NOW PARTICULARLY FOR PREGNANT WOMEN AND GETTING THAT PEOPLE. REPORTER: A TOTAL OF 50 PEOPLE IN ALLEGHENY COUNTY HAVE BEEN TESTED FOR ZIKA VIRUS. FIRST CONFIRMED CASE. OTHER CASES HAVE COME BACK NEGATIVE BUT THERE ARE STILL HEALTH DEPARTMENT IS WAITING ON FROM THE CDC. IT COULD STILL BE SEVERAL MORE WEEKS UNTIL WE KNOW ANY MORE http://www.wtae.com/news/allegheny-county-resident-tests-positive-for-zika-virus/38748930

Video of news conference http://www.wtae.com/news/news-conference-allegheny-county-confirms-first-zika-case/38750804

Allegheny County Resident Tests Positive For Zika VirusMarch 29, 2016 3:48 PMFiled Under: Allegheny County, Dr. Karen Hacker, health department, World Health Organization, Zika 12PITTSBURGH (KDKA) — An Allegheny County resident has tested positive for the Zika virus. According to a release from the county, the tests were conducted in February and the results were received Tuesday. The person who tested positive is a male who had traveled to the affected area. ADVERTISINGinRead invented by TeadsDr. Karen Hacker, Director of the Health Department, provided a briefing on the results and what this means for residents. “We want to remind residents that there is no current risk of contracting Zika in Allegheny County. For those traveling to countries affected by Zika, we urge caution. Pregnant women particularly should avoid travel to affected countries.” said Hacker. The virus is primarily transmitted through the bite of an infected Aedesspecies mosquito, which is common in warm climates. The most common symptoms are fever, rash, joint pain, and conjunctivitis. The sickness has been linked to fetal malformations. In January, the World Health Organization declared Zika an international health emergency. WHO estimates there could be up to 4 million cases of the virus in the Americas in the next year. This is a developing story, stay with KDKA and KDKA.com for more information. http://pittsburgh.cbslocal.com/2016/03/29/allegheny-county-resident-tests-positive-for-zika/

Allegheny County confirms first case of Zika virusBy Kirstin Kennedy [email protected] 30 min ago 0 An Allegheny County resident tested positive for the Zika virus, marking the first confirmed case in the county. The unidentified man contracted the virus while traveling in an affected area, according to the Allegheny County Health Department. Lab results arrived at the department Tuesday. The man was tested for Zika in February and has since recovered from the virus, officials said. Health officials said there is no current risk of contracting Zika in western Pennsylvania. The primary mosquito that carries the disease is not found in Pennsylvania, experts say, but one type of mosquito that can potentially carry the disease has been reported in the state. Zika virus, which has broken out in several South American countries, is transmitted to humans primarily through mosquito bites. There is no vaccine or treatment for the infection, and officials believe it may be linked to microcephaly, a brain defect developed in fetuses. Zika is generally a mild illness that lasts between two and seven days. Symptoms include fever, rash, muscle and joint pain, conjunctivitis and headache, and are treated with rest, fluids and medicine to relieve fevers, according to officials. People who have traveled to affected areas who have not been tested, but want to know if they should be, are being instructed to contact their primary physician. http://www.timesonline.com/news/local_news/allegheny-county-confirms-first-case-of-zika-virus/article_ad64b264-f5ef-11e5-95e7-9fdcc165f713.html

Zika virus confirmed in Allegheny County BY THE TRIBUNE-REVIEW | Tuesday, March 29, 2016, 4:21 p.m. Email NewslettersSign up for one of our email newsletters. Updated 27 minutes ago The Zika virus has been confirmed for the first time in Allegheny County, according to the county's Health Department. Results arrived Tuesday showing a man who was tested in February has the virus, according to a Health Department news release. “We want to remind residents that there is no current risk of contracting Zika in Allegheny County. For those traveling to countries affected by Zika, we urge caution. Pregnant women particularly should avoid travel to affected countries,” said Dr. Karen Hacker, the Health Department's director. The mosquito-borne virus has been associated in South America with microcephaly, a condition in which babies are born with abnormally small heads, but most people who get it experience minor symptoms such as fever, rash, joint pain and red eyes, according to a new release the Health Department. No vaccine for the virus exists. The Centers for Disease Control and Prevention recommends pregnant women who have traveled to areas where Zika is prevalent get tested. Fifty county residents have been approved for Zika testing, the release states. State Department of Health data from Monday showed 11 Pennsylvanians had the virus, and 211 were awaiting results. Mosquito transmission of the virus has not been reported in Allegheny County or Pennsylvania, but the county Health Department recommends residents protect themselves from infect-borne infections by using bug spray containing DEET and by eliminating standing pools of water where mosquitoes might breed. http://triblive.com/news/adminpage/10223098-74/department-virus-county

First Allegheny County resident tests positive for Zika virusUPDATED 5:14 PM EDT Mar 29, 2016NEXT STORY Mt. Lebanon man found dead after Easter disturbance was strangled Text Size:AAA SHOW TRANSCRIPTPITTSBURGH —An Allegheny County man tested positive for the Zika virus, marking the county's first confirmed case, health officials said Tuesday. SHOULD U.S. HAND OUT CONDOMS TO STOP ZIKA? Welcome to the U.S.! Have a condom! That's the message millions of travelers might hear when stepping off an airplane, as public health experts look for ways to stop the Zika virus. New guidelines from the Centers for Disease Control and Prevention, re... MOREELMO JOINS CAMPAIGN AGAINST ZIKA VIRUSTwo members of the "Sesame Street" Muppets are joining the campaign against the Zika virus. Elmo and his aqua green-skinned friend Raya will now be spreading the word to children and families about the disease. MORECDC UPDATES ZIKA ADVICE FOR SEX AND PREGNANCYWomen with confirmed cases of the Zika virus or who have had symptoms should wait at least 8 weeks after symptoms start before trying to get pregnant, the U.S. Centers for Disease Control and Prevention said. MOREImplications to the public are "minimal," said Dr. Karen Hacker, director of the county Health Department. VIDEO: Watch Kelly Brennan's report from outside the Allegheny Health Department The patient, a man, was tested in February and is no longer ill, but the test results were not received until Tuesday, Hacker said. The man had traveled to a country that was among the areas affected by the virus, Hacker said. He is one of 50 people who have been tested in Allegheny County. More: CDC updates Zika advice for sex and pregnancy More: Should U.S. hand out condoms to stop Zika? Below is the county's official statement... The Allegheny County Health Department (ACHD) today reported the first confirmed case of the Zika virus (Zika) in the county. The individual who contracted Zika is a male who had traveled to an affected area. The individual was tested in February, but results only arrived today. A total of 50 residents have been approved for Zika testing to date. Today’s result has been the only confirmed case to date. “We want to remind residents that there is no current risk of contracting Zika in Allegheny County. For those traveling to countries affected by Zika, we urge caution. Pregnant women particularly should avoid travel to affected countries.” said Dr. Karen Hacker, Director of the Allegheny County Health Department.” The Zika virus is primarily transmitted through the bite of an infected Aedes species mosquito, which is common in warm climates. The most common symptoms of Zika are fever, rash, joint pain, and conjunctivitis (red eyes). The illness is usually mild with symptoms lasting for several days to a week, although the majority of persons infected with the virus do not have any symptoms. Zika virus infection has been linked to fetal malformations. There is no vaccine to prevent, or medicine to treat, Zika virus infection. While local mosquito transmission of Zika has not been documented in Allegheny County or Pennsylvania, residents are still urged to protect themselves from insect borne infections as the weather gets warmer. Insect repellant containing DEET should be used, and removing standing water from property can also help to alleviate mosquito breeding. Ongoing updates on additional confirmed cases will be posted on the Health Department’s website. Additional resources, including links to the PA Department of Health and the Centers for Disease Control and Prevention, may also be found on the site. The page also contains information on the number of residents tested, and the number of confirmed cases of the virus. Individuals who have traveled to affected areas who have not been tested, but want to know if they should be tested, should contact their primary physician, or may call the Allegheny County Health Department at 412-687-ACHD (2243). http://www.wtae.com/news/allegheny-county-resident-tests-positive-for-zika-virus/38748930

Allegheny County reports first confirmed case of ZikaCounty’s health department says a resident — the 12th in the state — tested positive for the virus.March 29, 2016 4:42 PM Luis Robayo/AFP/Getty Images Pittsburgh Post-GazetteAn Allegheny County resident has tested positive for the Zika virus, the first local confirmation of the mosquito-borne disease as an outbreak rages abroad, the county health department said this afternoon. At least 11 others in Pennsylvania have come down with Zika since the state Department of Health began issuing regular updates in January, according to state figures. All the cases appear related to the outbreak that began last May in Brazil and has spread through other South and Central American countries. State health officials said the infected resident is a male who had traveled to an affected country. “We want to remind residents that there is no current risk of contracting Zika in Allegheny County. For those traveling to countries affected by Zika, we urge caution. Pregnant women particularly should avoid travel to affected countries.” Karen Hacker, the county’s health department director, said in a release. Most infected people show no symptoms, although pregnant women may face an elevated risk of complications. No Zika-infected mosquitoes have been reported in the United States. http://www.post-gazette.com/local/region/2016/03/29/Allegheny-County-reports-first-confirmed-case-of-Zika/stories/201603290153 County health officials are expected to release more details late this afternoon about the local case. First Published March 29, 2016 4:05 PM

Map Update https://www.google.com/maps/d/edit?hl=en&hl=en&authuser=0&authuser=0&mid=zv94AJqgUct4.kT4qLMXp3SLU

The Allegheny County Health Department (ACHD) today reported the first confirmed case of the Zika virus (Zika) in the county. The individual who contracted Zika is a male who had traveled to an affected area. The individual was tested in February, but results only arrived today. http://www.alleghenycounty.us/News/2016/6442452583.aspx

Zika virus cases in Canada, as of March 29, 2016CountryLocally acquiredTravel-relatedCanada033

A report on the outbreak of Zika virus on Easter Island, South Pacific, 2014.Tognarelli,J., Ulloa,S., Villagra,E., Lagos,J., Aguayo,C., Fasce,R., Parra,B., Mora,J., Becerra,N., Lagos,N., Vera,L., Olivares,B., Vilches,M. and Fernandez,J. (11-26-2015) Arch. Virol. PMID: 26611910 CitationGo to:Sequences in this data setKM078979.1Zika virus strain CHI2909014 NS5 protein gene, partial cdsKM078978.1Zika virus strain CHI2908914 NS5 protein gene, partial cdsKM078977.1Zika virus strain CHI2908714 NS5 protein gene, partial cdsKM078976.1Zika virus strain CHI2871014 NS5 protein gene, partial cdsKM078975.1Zika virus strain CHI2759614 NS5 protein gene, partial cdsKM078974.1Zika virus strain CHI2759514 NS5 protein gene, partial cdsKM078973.1Zika virus strain CHI2759014 NS5 protein gene, partial cdsKM078972.1Zika virus strain CHI2758514 NS5 protein gene, partial cdsKM078971.1Zika virus strain CHI2613014 NS5 protein gene, partial cdsKM078970.1Zika virus strain CHI2490414 NS5 protein gene, partial cdsKM078969.1Zika virus strain CHI2488314 NS5 protein gene, partial cdsKM078968.1Zika virus strain CHI2488214 NS5 protein gene, partial cdsKM078967.1Zika virus strain CHI2487714 NS5 protein gene, partial cdsKM078966.1Zika virus strain CHI2348014 NS5 protein gene, partial cdsKM078965.1Zika virus strain CHI2759214 NS5 protein gene, partial cdsKM078964.1Zika virus strain CHI2758914 NS5 protein gene, partial cdsKM078963.1Zika virus strain CHI2758614 NS5 protein gene, partial cdsKM078962.1Zika virus strain CHI2612714 NS5 protein gene, partial cdsKM078961.1Zika virus strain CHI2612114 NS5 protein gene, partial cdsKM078960.1Zika virus strain CHI2611714 NS5 protein gene, partial cdsKM078959.1Zika virus strain CHI2611514 NS5 protein gene, partial cdsKM078958.1Zika virus strain CHI2611214 NS5 protein gene, partial cdsKM078957.1Zika virus strain CHI2489814 NS5 protein gene, partial cdsKM078956.1Zika virus strain CHI2487814 NS5 protein gene, partial cdsKM078955.1Zika virus strain CHI2487414 NS5 protein gene, partial cdsKM078954.1Zika virus strain CHI2487314 NS5 protein gene, partial cdsKM078953.1Zika virus strain CHI2347814 NS5 protein gene, partial cdsKM078952.1Zika virus strain CHI2347614 NS5 protein gene, partial cdsKM078951.1Zika virus strain CHI2347414 NS5 protein gene, partial cdsKM078950.1Zika virus strain CHI2347214 NS5 protein gene, partial cdsKM078949.1Zika virus strain CHI2283914 NS5 protein gene, partial cdsKM078948.1Zika virus strain CHI2283814 NS5 protein gene, partial cdsKM078947.1Zika virus strain CHI2283514 NS5 protein gene, partial cdsKM078946.1Zika virus strain CHI2283014 NS5 protein gene, partial cdsKM078945.1Zika virus strain CHI2091414 NS5 protein gene, partial cdsKM078944.1Zika virus strain CHI2091114 NS5 protein gene, partial cdsKM078943.1Zika virus strain CHI2282814 NS5 protein gene, partial cdsKM078942.1Zika virus strain CHI1805114 NS5 protein gene, partial cdsKM078941.1Zika virus strain CHI1805014 NS5 protein gene, partial cdsKM078940.1Zika virus strain CHI1757714 NS5 protein gene, partial cdsKM078939.1Zika virus strain CHI1805314 NS5 protein gene, partial cdsKM078938.1Zika virus strain CHI1472814 NS5 protein gene, partial cdsKM078937.1Zika virus strain CHI1410414 NS5 protein gene, partial cdsKM078936.1Zika virus strain CHI1410214 NS5 protein gene, partial cdsKM078935.1Zika virus strain CHI1379614 NS5 protein gene, partial cdsKM078934.1Zika virus strain CHI1379514 NS5 protein gene, partial cdsKM078933.1Zika virus strain CHI1058514 NS5 protein gene, partial cdsKM078932.1Zika virus strain CHI1131214 NS5 protein gene, partial cdsKM078931.1Zika virus strain CHI2908814 NS5 protein gene, partial cdsKM078930.1Zika virus strain CHI2283714 NS5 protein gene, partial cdsKM078929.1Zika virus strain CHI1805214 NS5 protein gene, partial cds

Mar. 29, 2016 Department of Health Daily Zika UpdateNo New Cases TodayContact:Communications [email protected](850) 245-4111 Tallahassee, Fla. — In an effort to keep Florida residents and visitors safe and aware about the status of the Zika virus, the Florida Department of Health will issue a Zika virus update each week day at 2 p.m. Updates will include a CDC-confirmed Zika case count by county and information to better keep Floridians prepared. There are no new cases today. Of the cases confirmed in Florida, four cases are still exhibiting symptoms. According to the CDC, symptoms associated with the Zika virus last between seven to 10 days. Based on CDC guidance, several pregnant women who have traveled to countries with local-transmission of Zika have received antibody testing, and of those, four have tested positive for the Zika virus. The CDC recommends that a pregnant woman with a history of Zika virus and her provider should consider additional ultrasounds. It is recommended that women who are pregnant or thinking of becoming pregnant postpone travel to Zika affected areas. County Number of Cases (all travel related) Alachua 4 Brevard 2 Broward 11 Clay 1 Collier 1 Hillsborough 3 Lee 3 Miami-Dade 32 Orange 5 Osceola 4 Polk 2 Santa Rosa 1 Seminole 1 St. Johns 1 Cases involving pregnant women* 4 Total 75 *Counties of pregnant women will not be shared. On Feb. 12, Governor Scott directed the State Surgeon General to activate a Zika Virus Information Hotline for current Florida residents and visitors, as well as anyone planning on traveling to Florida in the near future. The hotline, managed by the Department of Health, has assisted 1,197 callers since it launched. The number for the Zika Virus Information Hotline is 1-855-622-6735. All cases are travel-associated. There have been no locally-acquired cases of Zika in Florida. For more information on the Zika virus, clickhere. The department urges Floridians to drain standing water weekly, no matter how seemingly small. A couple drops of water in a bottle cap can be a breeding location for mosquitoes. Residents and visitors also need to use repellents when enjoying the Florida outdoors. More Information on DOH action on Zika: On Feb. 3, Governor Scott directed the State Surgeon General to issue a Declaration of Public Health Emergency for the counties of residents with travel-associated cases of Zika. The Declaration currently includes the 14 affected counties – Alachua, Brevard, Broward, Clay, Collier, Hillsborough, Lee, Miami-Dade, Orange, Osceola, Polk, Santa Rosa, Seminole and St. Johns – and will be updated as needed. DOH encourages Florida residents and visitors to protect themselves from all mosquito-borne illnesses by draining standing water; covering their skin with repellent and clothing; and covering windows with screens. DOH has a robust mosquito-borne illness surveillance system and is working with the CDC, the Florida Department of Agriculture and Consumer Services and local county mosquito control boards to ensure that the proper precautions are being taken to protect Florida residents and visitors. Florida currently has the capacity to test 4,072 people for active Zika virus and 1,711 for Zika antibodies. Federal Guidance on Zika: According to the CDC, Zika illness is generally mild with a rash, fever and joint pain. CDC researchers are examining a possible link between the virus and harm to unborn babies exposed during pregnancy. The FDA released guidance regarding donor screening, deferral and product management to reduce the risk of transfusion-transmission of Zika virus. Additional information is available on the FDA website here. The CDC has put out guidance related to the sexual transmission of the Zika virus. This includes the CDC recommendation that if you have traveled to a country with local transmission of Zika you should abstain from unprotected sex. For more information on Zika virus, click here. About the Florida Department of Health The department works to protect, promote and improve the health of all people in Florida through integrated state, county and community efforts. Follow us on Twitter at @HealthyFla and on Facebook. For more information about the Florida Department of Health please visit www.FloridaHealth.gov. http://www.floridahealth.gov/newsroom/2016/03/032916-zika-update.html

Puerto Rico Sees Rise in Zika Cases, Paralyzing ConditionBy THE ASSOCIATED PRESSSAN JUAN, Puerto Rico — Mar 28, 2016, 5:31 PM ET 9SHARES Email Puerto Rico says more than 100 new cases of the mosquito-borne Zika virus have been reported in the past week. Health authorities said Monday that the U.S. territory now has 350 cases, 40 of which involve pregnant women. Experts think Zika infections may be linked to microcephaly, which causes babies to have unusually small heads and brain damage. The paralyzing condition known as Guillain-Barre syndrome also is being looked for possible links to Zika, and Puerto Rican officials said two news cases of that were reported, for a total of three cases. Six people have been hospitalized. The U.S. Centers for Disease Control and Prevention has requested at least $225 million in federal funds to fight Zika in Puerto Rico. http://abcnews.go.com/International/wireStory/puerto-rico-sees-rise-zika-cases-paralyzing-condition-37986361

Zika Virus InformationAs of March 28, 2016 there are no confirmed cases of Zika virus in South Carolina.