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Isolate name: A/turkey/Poland/78/2016 Isolate ID: EPI_ISL_240107 Passage details/history: swab sample Type: A / H5N8 Lineage: Sample information Collection date: 2016-12-16 Host Turkey Additional host information: Domestic status: Domestic Is vaccinated: Location: Poland / Lubusz Voivodeship Additional location information: Health status: Sick Specimen source: Tracheal swab Strain or commercial product name used for vaccination: Institute information Originating lab: Sample ID given by the sample provider: Address: Submitting lab: National Veterinary Research Institut Poland, PIWet-PIB Sample ID given by the submitting laboratory: Authors: E. Swieton, K. Smietanka Address: National Veterinary Research Institut Poland, PIWet-PIB 57 Partyzantów Avenue 24-100 Puławy Poland Publication Publication In vivo antiviral resistance Phenotype Genotype Unspecified Antiviral resistance tested by experimental procedures Adamantanes: Unknown Oseltamivir: Unknown Zanamivir: Unknown Peramivir: Unknown Other: Unknown Additional information Antigenic characterization: Note: Sequence segment identifier length accession # INSDC Sequence HA A/turkey/Poland/78/2016 1725 EPI869930 Submitter information Submitter: Świętoń, Edyta Submission Date: 2017-01-02 Last modifier: Świętoń, Edyta Last modified: 2017-01-02 Address: National Veterinary Research Institut Poland, PIWet-PIB 57 Partyzantów Avenue 24-100 Puławy Poland

Align Segment-ID Name Score E-Value Identity EPI869931 A/turkey/Poland/83/2016 (A/H5N8) segment 4 (HA) 3147.8 0.000000e+00 1704/1704 (100%) EPI869930 A/turkey/Poland/78/2016 (A/H5N8) segment 4 (HA) 3144.1 0.000000e+00 1703/1704 (99%) EPI864746 A/mute swan/Croatia/85/2016 (A/H5N8) segment 4 (HA) 3131.2 0.000000e+00 1701/1704 (99%) EPI861568 A/mute swan/Croatia/70/2016 (A/H5N8) segment 4 (HA) 3131.2 0.000000e+00 1701/1704 (99%) EPI869924 A/domestic goose/Poland/33/2016 (A/H5N8) segment 4 (HA) 3127.5 0.000000e+00 1700/1704 (99%) EPI869929 A/mute swan/Poland/108/2016 (A/H5N8) segment 4 (HA) 3125.7 0.000000e+00 1700/1704 (99%) EPI861572 A/mute swan/Croatia/78/2016 (A/H5N8) segment 4 (HA) 3125.7 0.000000e+00 1700/1704 (99%) EPI869809 A/duck/France/161108h/2016 (A/H5N8) segment 4 (HA) 3120.1 0.000000e+00 1699/1704 (99%) EPI869926 A/domestic goose/Poland/72/2016 (A/H5N8) segment 4 (HA) 3116.4 0.000000e+00 1698/1704 (99%) EPI869687 A/decoy_duck/France/161104e/2016 (A/H5N8) segment 4 (HA) 3116.4 0.000000e+00 1698/1704 (99%) EPI868848 A/turkey/England/052131/2016 (A/H5N8) segment 4 (HA) 3114.6 0.000000e+00 1698/1704 (99%) EPI859212 A/tufted_duck/Germany-SH/R8446/2016 (A/H5N8) segment 4 (HA) 3114.6 0.000000e+00 1698/1704 (99%) EPI836614 A/common tern /Uvs-Nuur Lake/26/2016 (A/H5N8) segment 4 (HA) 3114.6 0.000000e+00 1698/1704 (99%) EPI836606 A/grey heron /Uvs-Nuur Lake/20/2016 (A/H5N8) segment 4 (HA) 3114.6 0.000000e+00 1698/1704 (99%) EPI823756 A/black-headed gull/Tyva/41/2016 (A/H5N8) segment 4 (HA) 3114.6 0.000000e+00 1698/1704 (99%) EPI823748 A/wild duck/Tyva/35/2016 (A/H5N8) segment 4 (HA) 3114.6 0.000000e+00 1698/1704 (99%) EPI823460 A/great crested grebe/Tyva/34/2016 (A/H5N8) segment 4 (HA) 3114.6 0.000000e+00 1698/1704 (99%) EPI773757 A/great crested grebe/Uvs-Nuur Lake/341/2016 (A/H5N8) segment 4 (HA) 3114.6 0.000000e+00 1699/1705 (99%) EPI859650 A/wild duck/Germany-BW/R8455/2016 (A/H5N8) segment 4 (HA) 3109.0 0.000000e+00 1697/1704 (99%) EPI869927 A/chicken/Poland/79A/2016 (A/H5N8) segment 4 (HA) 3103.5 0.000000e+00 1696/1704 (99%) EPI774394 A/Bar-headed Goose/Qinghai/BTY17-LU/2016 (A/H5N8) segment 4 (HA) 3103.5 0.000000e+00 1696/1704 (99%) EPI774386 A/Bar-headed Goose/Qinghai/BTY17-B/2016 (A/H5N8) segment 4 (HA) 3103.5 0.000000e+00 1696/1704 (99%) EPI774310 A/Bar-headed Goose/Qinghai/BTY12-LU/2016 (A/H5N8) segment 4 (HA) 3103.5 0.000000e+00 1696/1704 (99%) EPI774242 A/Bar-headed Goose/Qinghai/BTY8-LU/2016 (A/H5N8) segment 4 (HA) 3103.5 0.000000e+00 1696/1704 (99%) EPI774234 A/Bar-headed Goose/Qinghai/BTY8-B/2016 (A/H5N8) segment 4 (HA) 3103.5 0.000000e+00 1696/1704 (99%) EPI774121 A/Bar-headed Goose/Qinghai/BTY1-LV/2016 (A/H5N8) segment 4 (HA) 3103.5 0.000000e+00 1696/1704 (99%) EPI774113 A/Bar-headed Goose/Qinghai/BTY1-B/2016 (A/H5N8) segment 4 (HA) 3103.5 0.000000e+00 1696/1704 (99%) EPI869928 A/chicken/Poland/85A/2016 (A/H5N8) segment 4 (HA) 3098.0 0.000000e+00 1695/1704 (99%) EPI863865 A/Common Goldeneye/Sweden/SVA161117KU0322/SZ0002165/2016 (A/H5N8) segment 4 (HA) 3098.0 0.000000e+00 1695/1704 (99%) EPI858844 A/painted stork/India/10CA03/2016 (A/H5N8) segment 4 (HA) 3098.0 0.000000e+00 1695/1704 (99%) EPI774475 A/Brown-headed Gull/Qinghai/ZTO5-K/2016 (A/H5N8) segment 4 (HA) 3098.0 0.000000e+00 1695/1704 (99%) EPI774458 A/Brown-headed Gull/Qinghai/ZTO4-B/2016 (A/H5N8) segment 4 (HA) 3098.0 0.000000e+00 1695/1704 (99%) EPI774450 A/Brown-headed Gull/Qinghai/ZTO3-LU/2016 (A/H5N8) segment 4 (HA) 3098.0 0.000000e+00 1695/1704 (99%) EPI774402 A/Bar-headed Goose/Qinghai/BTY18-B/2016 (A/H5N8) segment 4 (HA) 3098.0 0.000000e+00 1695/1704 (99%) EPI774378 A/Bar-headed Goose/Qinghai/BTY16-LU/2016 (A/H5N8) segment 4 (HA) 3098.0 0.000000e+00 1695/1704 (99%) EPI774326 A/Bar-headed Goose/Qinghai/BTY13-LU/2016 (A/H5N8) segment 4 (HA) 3098.0 0.000000e+00 1695/1704 (99%) EPI774318 A/Bar-headed Goose/Qinghai/BTY13-B/2016 (A/H5N8) segment 4 (HA) 3098.0 0.000000e+00 1695/1704 (99%) EPI774302 A/Bar-headed Goose/Qinghai/BTY12-B/2016 (A/H5N8) segment 4 (HA) 3098.0 0.000000e+00 1695/1704 (99%) EPI774277 A/Bar-headed Goose/Qinghai/BTY10-LU/2016 (A/H5N8) segment 4 (HA) 3098.0 0.000000e+00 1695/1704 (99%) EPI774267 A/Bar-headed Goose/Qinghai/BTY10-B/2016 (A/H5N8) segment 4 (HA) 3098.0 0.000000e+00 1695/1704 (99%) EPI774259 A/Bar-headed Goose/Qinghai/BTY9-LU/2016 (A/H5N8) segment 4 (HA) 3098.0 0.000000e+00 1695/1704 (99%) EPI774251 A/Bar-headed Goose/Qinghai/BTY9-B/2016 (A/H5N8) segment 4 (HA) 3098.0 0.000000e+00 1695/1704 (99%) EPI774226 A/Bar-headed Goose/Qinghai/BTY7-LU2/2016 (A/H5N8) segment 4 (HA) 3098.0 0.000000e+00 1695/1704 (99%) EPI774218 A/Bar-headed Goose/Qinghai/BTY7-LU1/2016 (A/H5N8) segment 4 (HA) 3098.0 0.000000e+00 1695/1704 (99%) EPI774210 A/Bar-headed Goose/Qinghai/BTY7-B/2016 (A/H5N8) segment 4 (HA) 3098.0 0.000000e+00 1695/1704 (99%) EPI774201 A/Bar-headed Goose/Qinghai/BTY6-LU/2016 (A/H5N8) segment 4 (HA) 3098.0 0.000000e+00 1695/1704 (99%) EPI774193 A/Bar-headed Goose/Qinghai/BTY6-B/2016 (A/H5N8) segment 4 (HA) 3098.0 0.000000e+00 1695/1704 (99%) EPI774185 A/Bar-headed Goose/Qinghai/BTY5-B/2016 (A/H5N8) segment 4 (HA) 3098.0 0.000000e+00 1695/1704 (99%) EPI774176 A/Bar-headed Goose/Qinghai/BTY4-LU/2016 (A/H5N8) segment 4 (HA) 3098.0 0.000000e+00 1695/1704 (99%) EPI774168 A/Bar-headed Goose/Qinghai/BTY4-B/2016 (A/H5N8) segment 4 (HA) 3098.0 0.000000e+00 1695/1704 (99%) EPI774159 A/Bar-headed Goose/Qinghai/BTY3-LU/2016 (A/H5N8) segment 4 (HA) 3098.0 0.000000e+00 1695/1704 (99%) EPI774150 A/Bar-headed Goose/Qinghai/BTY3-B/2016 (A/H5N8) segment 4 (HA) 3098.0 0.000000e+00 1695/1704 (99%) EPI858836 A/duck/India/10CA01/2016 (A/H5N8) segment 4 (HA) 3092.4 0.000000e+00 1694/1704 (99%) EPI774506 A/Great Black-headed Gull/Qinghai/YO1-B/2016 (A/H5N8) segment 4 (HA) 3092.4 0.000000e+00 1694/1704 (99%) EPI774490 A/Brown-headed Gull/Qinghai/ZTO6-SP/2016 (A/H5N8) segment 4 (HA) 3092.4 0.000000e+00 1694/1704 (99%) EPI774483 A/Brown-headed Gull/Qinghai/ZTO6-B/2016 (A/H5N8) segment 4 (HA) 3092.4 0.000000e+00 1694/1704 (99%) EPI774434 A/Brown-headed Gull/Qinghai/ZTO1-LU/2016 (A/H5N8) segment 4 (HA) 3092.4 0.000000e+00 1694/1704 (99%) EPI774410 A/Bar-headed Goose/Qinghai/BTY18-LU/2016 (A/H5N8) segment 4 (HA) 3092.4 0.000000e+00 1694/1704 (99%) EPI774369 A/Bar-headed Goose/Qinghai/BTY16-B/2016 (A/H5N8) segment 4 (HA) 3092.4 0.000000e+00 1694/1704 (99%) EPI774335 A/Bar-headed Goose/Qinghai/BTY14-B/2016 (A/H5N8) segment 4 (HA) 3092.4 0.000000e+00 1694/1704 (99%) EPI774294 A/Bar-headed Goose/Qinghai/BTY11-LU/2016 (A/H5N8) segment 4 (HA) 3092.4 0.000000e+00 1694/1704 (99%) EPI774286 A/Bar-headed Goose/Qinghai/BTY11-B/2016 (A/H5N8) segment 4 (HA) 3092.4 0.000000e+00 1694/1704 (99%) EPI774142 A/Bar-headed Goose/Qinghai/BTY2-LU/2016 (A/H5N8) segment 4 (HA) 3092.4 0.000000e+00 1694/1704 (99%) EPI774133 A/Bar-headed Goose/Qinghai/BTY2-B/2016 (A/H5N8) segment 4 (HA) 3092.4 0.000000e+00 1694/1704 (99%) EPI860231 A/wild duck/Poland/82A/2016 (A/H5N8) segment 4 (HA) 3088.7 0.000000e+00 1693/1704 (99%) EPI774466 A/Brown-headed Gull/Qinghai/ZTO5-B/2016 (A/H5N8) segment 4 (HA) 3086.9 0.000000e+00 1693/1704 (99%) EPI774442 A/Brown-headed Gull/Qinghai/ZTO3-B/2016 (A/H5N8) segment 4 (HA) 3086.9 0.000000e+00 1694/1705 (99%) EPI774352 A/Bar-headed Goose/Qinghai/BTY15-B/2016 (A/H5N8) segment 4 (HA) 3086.9 0.000000e+00 1693/1704 (99%) EPI863857 A/Chicken/Sweden/SVA161122KU0453/SZ0209321/2016 (A/H5N8) segment 4 (HA) 3081.3 0.000000e+00 1692/1704 (99%) EPI863849 A/Chicken/Sweden/SVA161122KU0453/SZ0209318/2016 (A/H5N8) segment 4 (HA) 3081.3 0.000000e+00 1692/1704 (99%) EPI863834 A/Chicken/Sweden/SVA161122KU0453/SZ0209317/2016 (A/H5N8) segment 4 (HA) 3081.3 0.000000e+00 1692/1704 (99%) EPI863826 A/Chicken/Sweden/SVA161122KU0453/SZ0209316/2016 (A/H5N8) segment 4 (HA) 3081.3 0.000000e+00 1692/1704 (99%) EPI774498 A/Brown-headed Gull/Qinghai/ZTO6-MU/2016 (A/H5N8) segment 4 (HA) 3081.3 0.000000e+00 1692/1704 (99%) EPI774426 A/Brown-headed Gull/Qinghai/ZTO1-B/2016 (A/H5N8) segment 4 (HA) 3081.3 0.000000e+00 1692/1704 (99%) EPI774361 A/Bar-headed Goose/Qinghai/BTY15-LU/2016 (A/H5N8) segment 4 (HA) 3081.3 0.000000e+00 1692/1704 (99%) EPI774344 A/Bar-headed Goose/Qinghai/BTY14-LU/2016 (A/H5N8) segment 4 (HA) 3075.8 0.000000e+00 1691/1704 (99%) EPI703608 A/duck/Eastern China/S1109/2014 (A/H5N8) segment 4 (HA) 3075.8 0.000000e+00 1691/1704 (99%) EPI681300 A/goose/Zhejiang/925104/2014 (A/H5N8) segment 4 (HA) 3009.3 0.000000e+00 1679/1704 (98%) EPI681299 A/goose/Zhejiang/925037/2014 (A/H5N8) segment 4 (HA) 3009.3 0.000000e+00 1679/1704 (98%) EPI703602 A/duck/Eastern China/S0215/2014 (A/H5N8) segment 4 (HA) 2998.2 0.000000e+00 1677/1704 (98%) EPI675774 A/duck/Liaoning/S1001/2014 (A/H5N8) segment 4 (HA) 2998.2 0.000000e+00 1677/1704 (98%) EPI681290 A/goose/Zhejiang/925106/2014 (A/H5N6) segment 4 (HA) 2987.2 0.000000e+00 1675/1704 (98%) EPI509698 A/breeder duck/Korea/Gochang1/2014 (A/H5N8) segment 4 (HA) 2976.1 0.000000e+00 1673/1704 (98%) EPI561495 A/Baikal teal/Korea/H52/2014 (A/H5N8) segment 4 (HA) 2965.0 0.000000e+00 1671/1704 (98%) EPI591879 A/duck/Jiangxi/23970/2013 (A/H0) segment 4 (HA) 2959.5 0.000000e+00 1670/1704 (98%) EPI703599 A/duck/Eastern China/S1210/2013 (A/H5N8) segment 4 (HA) 2953.9 0.000000e+00 1669/1704 (97%) EPI690792 A/goose/Jiangsu/QD5/2014 (A/H5N8) segment 4 (HA) 2953.9 0.000000e+00 1669/1704 (97%) EPI762158 A/goose/Eastern China/CZ/2013 (A/H5N8) segment 4 (HA) 2948.4 0.000000e+00 1668/1704 (97%) EPI703607 A/goose/Eastern China/S0408/2014 (A/H5N8) segment 4 (HA) 2948.4 0.000000e+00 1668/1704 (97%) EPI690808 A/goose/Yangzhou/0420/2014 (A/H5N8) segment 4 (HA) 2948.4 0.000000e+00 1669/1705 (97%) EPI690800 A/goose/Shandong/WFSG1/2014 (A/H5N8) segment 4 (HA) 2948.4 0.000000e+00 1668/1704 (97%) EPI602037 A/duck/Ningbo/3262/2013 (A/H0) segment 4 (HA) 2942.8 0.000000e+00 1667/1704 (97%) EPI583870 A/duck/Shaoxing/5240/2013 (A/H0) segment 4 (HA) 2942.8 0.000000e+00 1667/1704 (97%) EPI530985 A/duck/Zhejiang/W24/2013 (A/H5N8) segment 4 (HA) 2942.8 0.000000e+00 1667/1704 (97%) EPI762150 A/duck/Eastern China/JY/2014 (A/H5N8) segment 4 (HA) 2937.3 0.000000e+00 1667/1705 (97%) EPI530986 A/duck/Zhejiang/6D18/2013 (A/H5N8) segment 4 (HA) 2937.3 0.000000e+00 1666/1704 (97%) EPI507673 A/mallard duck/Shanghai/SH-9/2013 (A/H5N8) segment 4 (HA) 2937.3 0.000000e+00 1666/1704 (97%) EPI860239 A/tufted duck/Denmark/17740-1/2016 (A/H5N8) segment 4 (HA) 2933.6 0.000000e+00 1602/1609 (99%) EPI703595 A/duck/Eastern China/L1021/2012 (A/H5N8) segment 4 (HA) 2931.8 0.000000e+00 1665/1704 (97%) EPI681280 A/goose/Zhejiang/77166/2014 (A/H5N2) segment 4 (HA) 2928.1 0.000000e+00 1663/1702 (97%)

Isolate name: A/turkey/Poland/83/2016 Isolate ID: EPI_ISL_240108 Passage details/history: organ sample Type: A / H5N8 Lineage: Sample information Collection date: 2016-12-19 Host Turkey Additional host information: Domestic status: Domestic Is vaccinated: Location: Poland / Lubusz Voivodeship Additional location information: Health status: Dead Specimen source: Organ Strain or commercial product name used for vaccination: Institute information Originating lab: Sample ID given by the sample provider: Address: Submitting lab: National Veterinary Research Institut Poland, PIWet-PIB Sample ID given by the submitting laboratory: Authors: E. Swieton, K. Smietanka Address: National Veterinary Research Institut Poland, PIWet-PIB 57 Partyzantów Avenue 24-100 Puławy Poland Publication Publication In vivo antiviral resistance Phenotype Genotype Unspecified Antiviral resistance tested by experimental procedures Adamantanes: Unknown Oseltamivir: Unknown Zanamivir: Unknown Peramivir: Unknown Other: Unknown Additional information Antigenic characterization: Note: Sequence segment identifier length accession # INSDC Sequence HA A/turkey/Poland/83/2016 1725 EPI869931 Submitter information Submitter: Świętoń, Edyta Submission Date: 2017-01-02 Last modifier: Świętoń, Edyta Last modified: 2017-01-02 Address: National Veterinary Research Institut Poland, PIWet-PIB 57 Partyzantów Avenue 24-100 Puławy Poland

edit Name Isolate ID Subtype Passage PB2 PB1 PA HA NP NA MP NS HE P3 Collection date edit Name Isolate ID Subtype Passage PB2 PB1 PA HA NP NA MP NS HE P3 Collection date A/turkey/Poland/83/2016 EPI_ISL_240108 H5N8 organ sample --- --- --- 1725 --- --- --- --- --- --- 2016-12-19 A/turkey/Poland/78/2016 EPI_ISL_240107 H5N8 swab sample --- --- --- 1725 --- --- --- --- --- --- 2016-12-16 A/mute swan/Poland/108/2016 EPI_ISL_240106 H5N8 organ sample --- --- --- 1725 --- 1413 --- --- --- --- 2016-12-21 A/chicken/Poland/85A/2016 EPI_ISL_240105 H5N8 organ sample --- --- --- 1725 --- 1413 --- --- --- --- 2016-12-19 A/chicken/Poland/79A/2016 EPI_ISL_240104 H5N8 organ sample --- --- --- 1725 --- 1413 --- --- --- --- 2016-12-17 A/domestic goose/Poland/72/2016 EPI_ISL_240103 H5N8 organ sample --- --- --- 1725 --- 1413 --- --- --- --- 2016-12-14 A/domestic goose/Poland/33/2016 EPI_ISL_240102 H5N8 organ sample --- --- --- 1717 --- 1413 --- --- --- --- 2016-12-02

National Veterinary Research Institut Poland has released 7 sets (H5 and N8 or H5 only) of sequences. None of these sequences match the dominant sub-clade reported for Poland, Sweden, France, England, Germany, and Denmark. Three of the sequence match the Croatia / France sub-clade, while the other four are novel. Although 3 countries have reported H5N5, no sequences have been released. The two sets of novel sequences in Poland may be related to new constellations.

H5N5 map update https://www.google.com/maps/d/u/0/edit?mid=1sCuerlmBTcpi1QLzYCES_Nkv-nw&hl=en&ll=48.46249809605528%2C3.1300651875000085&z=5

H5N5 map update https://www.google.com/maps/d/u/0/edit?mid=1sCuerlmBTcpi1QLzYCES_Nkv-nw&hl=en&ll=45.68115037326884%2C13.08381553028562&z=9

Avian: found positive to the virus volatile lagoon Widgeon wild (like a duck) died in Artalina valley, near Grado. The Ministry of the analysis confirmed the presence of the formidable influenceof Ciro Vitiello Tags AVIAN ANIMALS December 31, 2016 LinkedIn Pinterest Test tubes for laboratory analysis in a photo archive DEGREE. Back avian alarm and hits the lagoon of Grado to the nature reserve of Cona. Two days ago the Institute Zooprofilattico delle Venezie of Padua, home of the National Reference Laboratory for Avian, confirmed positive for influenza type A virus, H5N5 subtype. The virus was found in organs taken from a widgeon wild - a kind of bird similar to ducks - found dead in Grado, in Artalina valley. It is a valley owned by the town of Grado, of land granted to the Cooperative fishermen. Analyses confirmed that it is highly pathogenic viruses. And the fear now is that the return of bird flu syndrome as in the mid-2000s. In this period of great migration, especially from the countries of Northern Europe, especially from Siberia, arriving at the island reserve of Cona to Grado thousands of birds. Among them at least 2,000 widgeon. Last month, precisely in relation to these migrations, in the conference room of the Island visitors center of Cona, it was held the conference "Ecology and evolution of influenza viruses in aquatic birds: the 2015-2016 data collected on the Island of Cona ". They were attended by the highest national representatives, with the presence of Professor Mauro Delogu, a professor in the Department of Veterinary Medical Sciences, University of Bologna. The message that emerged from the meeting was precisely that "the bird is far away from these areas, but we must always monitor the species that arrive from all over the world." Nothing was found, therefore, possible cases of bird flu. But in the statement issued by the Ministry of Health, is underlined "the serious European epidemiological situation, linked to the circulation of influenza viruses of highly pathogenic H5N8 in several Member States (Austria, Croatia, Denmark, Finland, France, Germany, Netherlands, Poland, United Kingdom, Romania, Serbia, Switzerland, Hungary and Sweden) for a total of 498 cases, of which 214 247 in domestic poultry and wild nell'avifauna, November 9 and December 7. " The same ministry, in fact, had already given the provisions for the further development of lifelong veterinary supervision, with particular emphasis on enforcing the biosecurity measures in industrial poultry farms, recommending to keep poultry indoors in densely populated areas . That's the case of wigeon found in Grado, you have been given more extraordinary control measures that provide for the immediate suspension of the exemption from the prohibition of continued use of the national hunting decoys belonging to the orders of Anseriformes and Charadriiformes throughout the national territory . "Prudence must be careful not to create alarm and still avoid touching the animals. Need to figure out if this avian viruses that have found the wigeon can be dangerous to humans. It is still early to tell. " This is the opinion ornithologist Fabio Perco, director of the SBIC, the Island Biological Station of Cona, after news branched from the Ministry of Health. http://messaggeroveneto.gelocal.it/udine/cronaca/2016/12/31/news/aviaria-trovato-in-laguna-volatile-positivo-al-virus-1.14643501

A case of highly pathogenic bird flu in a wild bird by Paola Treppo ABLE (Gorizia) - A case of bird flu in Friuli Venezia Giulia, in the area Grado , in the province of Gorizia, did raise the guard to the health authorities. On December 28 last year, in fact, the National Reference Centre for avian influenza the Livestock Research Institute delle Venezie confirmed positive for influenza virus "type A", for highly pathogenic (HPAI) subtype H5N5, in organs from a volatile wild found dead nell'Isontino. It was a widgeon that had been found by the provincial police Gorizia , along with two other animals of the same species. Have taken several provisions affecting farmers all over the national territory should be maintained, for example, the clear separation between poultry home, which must be closed, and the wild; the drinking and feeding facilities must be accessible to wild birds. The veterinarians will supervise the application of the measure by carrying out inspections also virological control with taking of swabs. http://www.ilgazzettino.it/nordest/udine/un_caso_di_influenza_aviaria_ad_alta_patogenicita_un_volatile_selvatico-2169750.html

H5N8 map update https://www.google.com/maps/d/edit?hl=en&hl=en&authuser=0&authuser=0&mid=1aNOepBDPUd0zdRnQE1UbSW8djsk&ll=45.70755620261788%2C13.337751962648781&z=14

Bird flu: the H5N5 outbreak in the province of Gorizia Posted on: December 30, 2016 Last updated: December 30, 2016 On December 28, 2016 was confirmed by the National Reference Center for influenza avian Institute Zooprofilattico delle Venezie, positive for influenza virus type A highly pathogenic (HPAI) subtype H5N5 , in organs from a wild bird found dead in the province of Gorizia. It is a Wigeon (Anas Penelope) that was recovered from the Gorizia Provincial Police, along with two other individuals of the same species, in the Grado lagoon . Soon we will be published the results of the phylogenetic analysis of the virus. The detailed update on the disease situation will be posted on the page: Topics> Diseases and pathogens> Bird flu> Epidemiological situation HPAI Italy

It is a Wigeon (Anas Penelope) that was recovered from the Gorizia Provincial Police, along with two other individuals of the same species, in the Grado lagoon . http://www.izsvenezie.it/influenza-aviaria-italia-2016-2/

Sequences producing significant alignments: Select:AllNone Selected:0 AlignmentsDownloadGenBankGraphicsDistance tree of resultsShow/hide columns of the table presenting sequences producing significant alignments Sequences producing significant alignments: Select for downloading or viewing reports Description Max score Total score Query cover E value Ident Accession Select seq gb|KY317939.1| Zika virus isolate ZIKV/Homo_sapiens/Colombia/2016/ZC204Se polyprotein gene, complete cds 18966 18966 100% 0.0 100% KY317939.1 Select seq gb|KY317936.1| Zika virus isolate ZIKV/Homo_sapiens/Colombia/2016/ZC188Se polyprotein gene, complete cds 18938 18938 100% 0.0 99% KY317936.1 Select seq gb|KY317938.1| Zika virus isolate ZIKV/Homo_sapiens/Colombia/2016/ZC199Se polyprotein gene, complete cds 18921 18921 100% 0.0 99% KY317938.1 Select seq gb|KX198135.2| Zika virus strain ZIKV/Homo sapiens/PAN/BEI-259634_V4/2016, complete genome 18910 18910 100% 0.0 99% KX198135.2 Select seq gb|KY014303.1| Zika virus isolate Zika virus/H.sapiens-wt/DOM/2016/BB-0127-SER polyprotein gene, complete cds 18905 18905 100% 0.0 99% KY014303.1 Select seq gb|KX156776.2| Zika virus strain ZIKV/Homo sapiens/PAN/CDC-259364_V1-V2/2015, complete genome 18899 18899 100% 0.0 99% KX156776.2 Select seq gb|KY317940.1| Zika virus isolate ZIKV/Homo_sapiens/Colombia/2016/ZC207Se polyprotein gene, complete cds 18894 18894 100% 0.0 99% KY317940.1 Select seq gb|KX156774.2| Zika virus strain ZIKV/Homo sapiens/PAN/CDC-259359_V1-V3/2015, complete genome 18894 18894 100% 0.0 99% KX156774.2 Select seq gb|KX156775.2| Zika virus strain ZIKV/Homo sapiens/PAN/CDC-259249_V1-V3/2015, complete genome 18888 18888 100% 0.0 99% KX156775.2 Select seq gb|KX087102.2| Zika virus strain ZIKV/Homo sapiens/COL/FLR/2015, complete genome 18888 18888 100% 0.0 99% KX087102.2 Select seq gb|KU820897.5| Zika virus isolate FLR polyprotein gene, complete cds 18888 18888 100% 0.0 99% KU820897.5 Select seq gb|KX247646.1| Zika virus isolate Zika virus/Homo sapiens/COL/UF-1/2016, complete genome 18888 18888 100% 0.0 99% KX247646.1 Select seq gb|KU647676.1| Zika virus strain MRS_OPY_Martinique_PaRi_2015 polyprotein gene, complete cds 18883 18883 100% 0.0 99% KU647676.1 Select seq gb|KY317937.1| Zika virus isolate ZIKV/Homo_sapiens/Colombia/2016/ZC192Se polyprotein gene, complete cds 18866 18866 100% 0.0 99% KY317937.1 Select seq gb|KX702400.1| Zika virus strain Zika virus/Homo sapiens/VEN/UF-1/2016, complete genome 18866 18866 100% 0.0 99% KX702400.1 Select seq gb|KX893855.1| Zika virus strain Zika virus/Homo sapiens/VEN/UF-2/2016, complete genome 18864 18864 100% 0.0 99% KX893855.1 Select seq gb|KU922960.1| Zika virus isolate MEX/InDRE/Sm/2016, complete genome 18860 18860 100% 0.0 99% KU922960.1 Select seq gb|KX548902.1| Zika virus isolate ZIKV/COL/FCC00093/2015 polyprotein gene, complete cds 18855 18855 100% 0.0 99% KX548902.1 Select seq gb|KU922923.1| Zika virus isolate MEX/InDRE/Lm/2016, complete genome 18855 18855 100% 0.0 99% KU922923.1 Select seq gb|KX447510.1| Zika virus isolate 1_0049_PF polyprotein gene, complete cds 18833 18833 100% 0.0 99% KX447510.1 Select seq gb|KU991811.1| Zika virus isolate Brazil/2016/INMI1 polyprotein gene, complete cds 18827 18827 100% 0.0 99% KU991811.1 Select seq gb|KY075932.1| Zika virus isolate ZIKV/Homo_sapiens/USA/2016/FL001Sa polyprotein gene, complete cds 18822 18822 100% 0.0 99% KY075932.1 Select seq gb|KX447512.1| Zika virus isolate 1_0181_PF polyprotein gene, complete cds 18822 18822 100% 0.0 99% KX447512.1 Select seq gb|KX369547.1| Zika virus strain PF13/251013-18, complete genome 18822 18822 100% 0.0 99% KX369547.1 Select seq gb|KU509998.3| Zika virus strain Haiti/1225/2014, complete genome 18822 18822 100% 0.0 99% KU509998.3 Select seq gb|KJ776791.2| Zika virus strain H/PF/2013, complete genome 18816 18816 100% 0.0 99% KJ776791.2 Select seq gb|KX447509.1| Zika virus isolate 1_0087_PF polyprotein gene, complete cds 18816 18816 100% 0.0 99% KX447509.1 Select seq gb|KX447513.1| Zika virus isolate 1_0134_PF polyprotein gene, complete cds 18811 18811 100% 0.0 99% KX447513.1 Select seq gb|KR872956.1| Zika virus strain 17829 polyprotein gene, complete cds 18805 18805 100% 0.0 99% KR872956.1 Select seq gb|KX197205.1| Zika virus isolate 9, complete genome 18805 18805 100% 0.0 99% KX197205.1 Select seq gb|KX447515.1| Zika virus isolate 1_0030_PF polyprotein gene, complete cds 18805 18805 100% 0.0 99% KX447515.1 Select seq gb|KX447511.1| Zika virus isolate 1_0015_PF polyprotein gene, complete cds 18805 18805 100% 0.0 99% KX447511.1 Select seq gb|KX280026.1| Zika virus isolate Paraiba_01, complete genome 18805 18805 100% 0.0 99% KX280026.1 Select seq gb|KU321639.1| Zika virus strain ZikaSPH2015, complete genome 18805 18805 100% 0.0 99% KU321639.1 Select seq gb|KX447514.1| Zika virus isolate 1_0035_PF polyprotein gene, complete cds 18800 18800 100% 0.0 99% KX447514.1 Select seq gb|KX051563.1| Zika virus isolate Haiti/1/2016, complete genome 18800 18800 100% 0.0 99% KX051563.1 Select seq gb|KX447516.1| Zika virus isolate 1_0111_PF polyprotein gene, complete cds 18794 18794 100% 0.0 99% KX447516.1 Select seq gb|KU729218.1| Zika virus isolate BeH828305 polyprotein gene, complete cds 18794 18794 100% 0.0 99% KU729218.1 Select seq gb|KU707826.1| Zika virus isolate SSABR1, complete genome 18794 18794 100% 0.0 99% KU707826.1 Select seq gb|KU365779.1| Zika virus strain BeH819966 polyprotein gene, complete cds 18794 18794 100% 0.0 99% KU365779.1 Select seq gb|KX262887.1| Zika virus isolate 103451, complete genome 18788 18788 100% 0.0 99% KX262887.1 Select seq gb|KX197192.1| Zika virus isolate ZIKV/H.sapiens/Brazil/PE243/2015, complete genome 18788 18788 100% 0.0 99% KX197192.1 Select seq gb|KU497555.1| Zika virus isolate Brazil-ZKV2015, complete genome 18785 18785 99% 0.0 99% KU497555.1 Select seq gb|KX811222.1| Zika virus isolate Brazil_2015_MG, complete genome 18783 18783 100% 0.0 99% KX811222.1 Select seq gb|KX694534.2| Zika virus strain ZIKV/Homo sapiens/HND/R103451/2015, complete genome 18777 18777 100% 0.0 99% KX694534.2 Select seq gb|KX879604.1| Zika virus isolate SN089, complete genome 18777 18777 100% 0.0 99% KX879604.1 Select seq gb|KU758877.1| Zika virus isolate 17271 polyprotein gene, complete cds 18777 18777 100% 0.0 99% KU758877.1 Select seq gb|KU926309.1| Zika virus isolate Rio-U1, complete genome 18777 18777 100% 0.0 99% KU926309.1 Select seq gb|KU365780.1| Zika virus strain BeH815744 polyprotein gene, complete cds 18777 18777 100% 0.0 99% KU365780.1 Select seq gb|KY014297.1| Zika virus isolate Zika virus/H.sapiens-wt/BRA/2016/FC-6864-URI polyprotein gene, complete cds 18776 18776 100% 0.0 99% KY014297.1 Select seq gb|KU940228.1| Zika virus isolate Bahia07, partial genome 18772 18772 100% 0.0 99% KU940228.1 Select seq gb|KU365777.1| Zika virus strain BeH818995 polyprotein gene, complete cds 18772 18772 100% 0.0 99% KU365777.1 Select seq gb|KY328289.1| Zika virus isolate HN16, complete genome 18766 18766 100% 0.0 99% KY328289.1 Select seq gb|KX879603.1| Zika virus isolate SN062, complete genome 18766 18766 100% 0.0 99% KX879603.1 Select seq gb|KU501217.1| Zika virus strain 8375 polyprotein gene, complete cds 18766 18766 100% 0.0 99% KU501217.1 Select seq gb|KU365778.1| Zika virus strain BeH819015 polyprotein gene, complete cds 18766 18766 100% 0.0 99% KU365778.1 Select seq gb|KU312312.1| Zika virus isolate Z1106033 polyprotein gene, complete cds 18766 18766 100% 0.0 99% KU312312.1 Select seq gb|KU729217.2| Zika virus isolate BeH823339 polyprotein gene, complete cds 18761 18761 100% 0.0 99% KU729217.2 Select seq gb|KU527068.1| Zika virus strain Natal RGN, complete genome 18761 18761 100% 0.0 99% KU527068.1 Select seq gb|KU501216.1| Zika virus strain 103344 polyprotein gene, complete cds 18761 18761 100% 0.0 99% KU501216.1 Select seq gb|KY014327.1| Zika virus isolate Zika virus/H.sapiens-wt/HND/2016/HU-ME167-PLA polyprotein gene, complete cds 18757 18757 100% 0.0 99% KY014327.1 Select seq gb|KY120348.1| Zika virus isolate CIENI551, complete genome 18755 18755 100% 0.0 99% KY120348.1 Select seq gb|KX447517.1| Zika virus isolate 1_0038_PF polyprotein gene, complete cds 18755 18755 100% 0.0 99% KX447517.1 Select seq gb|KX247632.1| Zika virus isolate MEX_I_7 polyprotein gene, complete cds 18755 18755 100% 0.0 99% KX247632.1 Select seq gb|KU937936.1| Zika virus isolate ZIKVNL00013 polyprotein gene, complete cds 18755 18755 100% 0.0 99% KU937936.1 Select seq gb|KU501215.1| Zika virus strain PRVABC59, complete genome 18755 18755 100% 0.0 99% KU501215.1 Select seq gb|KX269878.1| Zika virus isolate Haiti/2016/PD, complete genome 18752 18752 100% 0.0 99% KX269878.1 Select seq gb|KX087101.3| Zika virus strain ZIKV/Homo sapiens/PRI/PRVABC59/2015, complete genome 18750 18750 100% 0.0 99% KX087101.3 Select seq gb|KY014315.1| Zika virus isolate Zika virus/H.sapiens-wt/HND/2016/HU-ME152-SER polyprotein gene, complete cds 18750 18750 100% 0.0 99% KY014315.1 Select seq gb|KY014304.1| Zika virus isolate Zika virus/H.sapiens-wt/DOM/2016/BB-0180-SER polyprotein gene, complete cds 18750 18750 100% 0.0 99% KY014304.1 Select seq gb|KX601168.1| Zika virus strain ZIKV/Homo Sapiens/PRI/PRVABC59/2015, complete genome 18750 18750 100% 0.0 99% KX601168.1 Select seq gb|KX520666.1| Zika virus isolate HS-2015-BA-01 polyprotein gene, complete cds 18750 18750 100% 0.0 99% KX520666.1 Select seq gb|KX446951.2| Zika virus strain ZIKV/Aedes.sp/MEX/MEX_I-7/2016, complete genome 18744 18744 100% 0.0 99% KX446951.2 Select seq gb|KY014296.1| Zika virus isolate Zika virus/H.sapiens-wt/BRA/2016/FC-DQ131D1-URI polyprotein gene, complete cds 18744 18744 100% 0.0 99% KY014296.1 Select seq gb|KX806557.2| Zika virus isolate TS17-2016, complete genome 18744 18744 100% 0.0 99% KX806557.2 Select seq gb|KX856011.1| Zika virus strain ZIKV/Aedes sp./MEX_I-44/2016, complete genome 18744 18744 100% 0.0 99% KX856011.1 Select seq gb|KX377337.1| Zika virus strain PRVABC-59, complete genome 18744 18744 100% 0.0 99% KX377337.1 Select seq gb|KU926310.1| Zika virus isolate Rio-S1, complete genome 18744 18744 100% 0.0 99% KU926310.1 Select seq gb|KU820898.1| Zika virus isolate GZ01 polyprotein gene, complete cds 18744 18744 100% 0.0 99% KU820898.1 Select seq gb|KX446950.2| Zika virus strain ZIKV/Aedes.sp/MEX/MEX_2-81/2016, complete genome 18739 18739 100% 0.0 99% KX446950.2 Select seq gb|KU870645.1| Zika virus isolate FB-GWUH-2016, complete genome 18739 18739 100% 0.0 99% KU870645.1 Select seq gb|KY075939.1| Zika virus isolate ZIKV/Aedes_aegypti/USA/2016/FL08M polyprotein gene, complete cds 18733 18733 100% 0.0 99% KY075939.1 Select seq gb|KY075933.1| Zika virus isolate ZIKV/Homo_sapiens/USA/2016/FL008U polyprotein gene, complete cds 18733 18733 100% 0.0 99% KY075933.1 Select seq gb|KY003153.1| Zika virus strain ZIKV/34997/Pavia/2016 polyprotein gene, complete cds 18733 18733 100% 0.0 99% KY003153.1 Select seq gb|KU853013.1| Zika virus isolate Dominican Republic/2016/PD2, complete genome 18733 18733 100% 0.0 99% KU853013.1 Select seq gb|KU853012.1| Zika virus isolate Dominican Republic/2016/PD1, complete genome 18731 18731 100% 0.0 99% KU853012.1 Select seq gb|KY075934.1| Zika virus isolate ZIKV/Homo_sapiens/USA/2016/FL016U polyprotein gene, complete cds 18727 18727 100% 0.0 99% KY075934.1 Select seq gb|KY014300.1| Zika virus isolate Zika virus/H.sapiens-wt/DOM/2016/BB-0208-SER polyprotein gene, complete cds 18727 18727 100% 0.0 99% KY014300.1 Select seq dbj|LC190723.1| Zika virus genomic RNA, complete genome, strain: ZIKV/Hu/Yokohama/1/2016 18727 18727 100% 0.0 99% LC190723.1 Select seq gb|KX056898.1| Zika virus isolate Zika virus/GZ02/2016 polyprotein gene, complete cds 18727 18727 100% 0.0 99% KX056898.1 Select seq gb|KU955590.1| Zika virus isolate Z16019 polyprotein gene, complete cds 18727 18727 100% 0.0 99% KU955590.1 Select seq gb|KX766028.1| Zika virus isolate R114916, complete genome 18724 18724 100% 0.0 99% KX766028.1 Select seq gb|KY014321.1| Zika virus isolate Zika virus/H.sapiens-wt/DOM/2016/BB-0115-SER polyprotein gene, complete cds 18722 18722 100% 0.0 99% KY014321.1 Select seq gb|KU740184.2| Zika virus isolate GD01 polyprotein gene, complete cds 18722 18722 100% 0.0 99% KU740184.2 Select seq gb|KU761564.1| Zika virus isolate GDZ16001 polyprotein gene, complete cds 18722 18722 100% 0.0 99% KU761564.1 Select seq gb|KY014295.1| Zika virus isolate Zika virus/H.sapiens-wt/USA/2016/FL-010-URI polyprotein gene, complete cds 18716 18716 100% 0.0 99% KY014295.1 Select seq gb|KX842449.2| Zika virus isolate ZIKV/Homo_sapiens/USA/2016/FL010U polyprotein gene, complete cds 18716 18716 100% 0.0 99% KX842449.2 Select seq gb|KY120349.1| Zika virus isolate CIENI551, complete genome 18713 18713 100% 0.0 99% KY120349.1 Select seq gb|KY003154.1| Zika virus strain ZIKV/VR10599/Pavia/2016 polyprotein gene, complete cds 18711 18711 100% 0.0 99% KY003154.1 Select seq gb|KX766029.1| Zika virus isolate R116265, complete genome 18711 18711 100% 0.0 99% KX766029.1

LOCUS KY317939 10608 bp RNA linear VRL 27-DEC-2016 DEFINITION Zika virus isolate ZIKV/Homo_sapiens/Colombia/2016/ZC204Se polyprotein gene, complete cds. ACCESSION KY317939 VERSION KY317939.1 KEYWORDS . SOURCE Zika virus ORGANISM Zika virus Viruses; ssRNA viruses; ssRNA positive-strand viruses, no DNA stage; Flaviviridae; Flavivirus. REFERENCE 1 (bases 1 to 10608) AUTHORS Grubaugh,N., Rogers,T., Beutler,N., Fredeking,T., Gangavarupu,K., Oliveira,G., Robles-Sikisaka,R., Burton,D. and Andersen,K. TITLE Zika virus sequenced from Colombia, 2016 JOURNAL Unpublished REFERENCE 2 (bases 1 to 10608) AUTHORS Grubaugh,N., Rogers,T., Beutler,N., Fredeking,T., Gangavarupu,K., Oliveira,G., Robles-Sikisaka,R., Burton,D. and Andersen,K. TITLE Direct Submission JOURNAL Submitted (09-DEC-2016) Department of Immunology and Microbial Science, The Scripps Research Institute, 10550 North Torrey Pines Road, IMM-210, La Jolla, CA 92037, USA COMMENT ##Assembly-Data-START## Assembly Method :: NovoAlign v. V3.04 Sequencing Technology :: Illumina ##Assembly-Data-END## FEATURES Location/Qualifiers source 1..10608 /organism="Zika virus" /mol_type="genomic RNA" /isolate="ZIKV/Homo_sapiens/Colombia/2016/ZC204Se" /isolation_source="serum" /host="Homo sapiens" /db_xref="taxon:64320" /country="Colombia" /collection_date="06-Jan-2016" /collected_by="Antibody Systems Inc" CDS 80..10351 /codon_start=1 /product="polyprotein" /protein_id="APQ41785.1" /translation="MKNPKKKSGGFRIVNMLKRGVARVSPFGGLKRLPAGLLLGHGPI RMVLAILAFLRFTAIKPSLGLINRWGSVGKKEAMEIIKKFKKDLAAMLRIINARKEKK RRGAETSVGIVGLLLTTAMAAEVTRRGSAYYMYLDRKDAGEAISFPTTLGMNKCYIQI MDLGHMCDATMSYECPMLDEGVEPDDVDCWCNTTSTWVVYGTCHHKKGEARRSRRAVT LPSHSTRKLQTRSQTWLESREYTKHLIRVENWIFRNPGFALAAAAIAWLLGSSTSQKV IYLVMILLIAPAYSIRCIGVSNRDFVEGMSGGTWVDVVLEHGGCVTVMAQDKPTVDIE LVTTTVSNMAEVRSYCYEASISDMASDSRCPTQGEAYLDKQSDTQYVCKRTLVDRGWG NGCGLFGKGSLVTCAKFACSKKMTGKSIQPENLEYRIMLSVHGSQHSGMIVNDTGHET DENRAKVEITPNSPRAEATLGGFGSLGLDCEPRTGLDFSDLYYLTMNNKHWLVHKEWF HDIPLPWHAGADTGTPHWNNKEALVEFKDAHAKRQTVVVLGSQEGAVHTALAGALEAE MDGAKGRLSSGHLKCRLKMDKLRLKGVSYSLCTAAFTFTKIPAETLHGTVTVEVQYAG TDGPCKVPAQMAVDMQTLTPVGRLITANPVITESTENSKMMLELDPPFGDSYIVIGVG EKKITHHWHRSGSTIGKAFEATVRGAKRMAVLGDTAWDFGSVGGALNSLGKGIHQIFG AAFKSLFGGMSWFSQILIGTLLMWLGLNTKNGSISLMCLALGGVLIFLSTAVSADVGC SVDFSKKETRCGTGVFVYNDVEAWRDRYKYHPDSPRRLAAAVKQAWEDGICGISSVSR MENIMWRSVEGELNAILEENGVQLTVVVGSVKNPMWRGPQRLPVPVNELPHGWKAWGK SYFVRAAKTNNSFVVDGDTLKECPLKHRAWNSFLVEDHGFGVFHTSVWLKVREDYSLE CDPAVIGTAVKGKEAVHSDLGYWIESEKNDTWRLKRAHLIEMKTCEWPKSHTLWTDGI EESDLIIPKSLAGPLSHHNTREGYRTQMKGPWHSEELEIRFEECPGTKVHVEETCGTR GPSLRSTTASGRVIEEWCCRECTMPPLSFWAKDGCWYGMEIRPRKEPESNLVRSMVTA GSTDHMDHFSLGVLVILLMVQEGLKKRMTTKIIISTSMAVLVAMILGGFSMSDLAKLA ILMGATFAEMNTGGDVAHLALIAAFKVRPALLVSFIFRANWTPRESMLLALASCLLQT AISALEGDLMVLINGFALAWLAIRAMVVPRTDNITLAILAALTPLARGTLLVAWRAGL ATCGGFMLLSLKGKGSVKKNLPFVMALGLTAVRLVDPINVVGLLLLTRSGKRSWPPSE VLTAVGLICALAGGFAKADIEMAGPMAAVGLLIVSYVVSGKSVDMYIERAGDITWEKD AEVTGNSPRLDVALDESGDFSLVEDDGPPMREIILKVVLMTICGMNPIAIPFAAGAWY VYVKTGKRSGALWDVPAPKEVKKGETTDGVYRVMTRRLLGSTQVGVGVMQEGVFHTMW HVTKGSALRSGEGRLDPYWGDVKQDLVSYCGPWKLDAAWDGHSEVQLLAVPPGERARN IQTLPGIFKTKDGDIGAVALDYPAGTSGSPILDKCGRVIGLYGNGVVIKNGSYVSAIT QGRREEETPVECFEPSMLKKKQLTVLDLHPGAGKTRRVLPEIVREAIKTRLRTVILAP TRVVAAEMEEALRGLPVRYMTTAVNVTHSGTEIVDLMCHATFTSRLLQPIRVPNYNLY IMDEAHFTDPSSIAARGYISTRVEMGEAAAIFMTATPPGTRDAFPDSNSPIMDTEVEV PERAWSSGFDWVTDHSGKTVWFVPSVRNGNEIAACLTKAGKRVIQLSRKTFETEFQKT KHQEWDFVVTTDISEMGANFKADRVIDSRRCLKPVILDGERVILAGPMPVTHASAAQR RGRIGRNPNKPGDEYLYGGGCAETDEDHAHWLEARMLLDNIYLQDGLIASLYRPEADK VAAIEGEFKLRTEQRKTFVELMKRGDLPVWLAYQVASAGITYTDRRWCFDGTTNNTIM EDSVPAEVWTRHGEKRVLKPRWMDARVCSDHAALKSFKEFAAGKRGAAFGVMEALGTL PGHMTERFQEAIDNLAVLMRAETGSRPYKAAAAQLPETLETIMLLGLLGTVSLGIFFV LMRNKGIGKMGFGMVTLGASAWLMWLSEIEPARIACVLIVVFLLLVVLIPEPEKQRSP QDNQMAIIIMVAVGLLGLITANELGWLERTKSDLSHLMGRREEGATIGFSMDIDLRPA SAWAIYAALTTFITPAVQHAVTTSYNNYSLMAMATQAGVLFGMGKGMPFYAWDFGVPL LMIGCYSQLTPLTLIVAIILLVAHYMYLIPGLQAAAARAAQKRTAAGIMKNPVVDGIV VTDIDTMTIDPQVEKKMGQVLLIAVAVSSAILSRTAWGWGEAGALITAATSTLWEGSP NKYWNSSTATSLCNIFRGSYLAGASLIYTVTRNAGLVKRRGGGTGETLGEKWKARLNQ MSALEFYSYKKSGITEVCREEARRALKDGVATGGHAVSRGSAKLRWLVERGYLQPYGK VIDLGCGRGGWSYYAATIRKVQEVKGYTKGGPGHEEPVLVQSYGWNIVRLKSGVDVFH MAAEPCDTLLCDIGESSSSPEVEEARTLRVLSMVGDWLEKRPGAFCIKVLCPYTSTMM ETLERLQRRYGGGLVRVPLSRNSTHEMYWVSGAKSNTIKSVSTTSQLLLGRMDGPRRP VKYEEDVNLGSGTRAVVSCAEAPNMKIIGNRIERIRSEHAETWFFDENHPYRTWAYHG SYEAPTQGSASSLINGVVRLLSKPWDVVTGVTGIAMTDTTPYGQQRVFKEKVDTRVPD PQEGTRQVMSMVSSWLWKELGKHKRPRVCTKEEFINKVRSNAALGAIFEEEKEWKTAV EAVNDPRFWALVDKEREHHLRGECQSCVYNMMGKREKKQGEFGKAKGSRAIWYMWLGA RFLEFEALGFLNEDHWMGRENSGGGVEGLGLQRLGYVLEEMSRIPGGRMYADDTAGWD TRISRFDLENEALITNQMEKGHRALALAIIKYTYQNKVVKVLRPAEKGKTVMDIISRQ DQRGSGQVVTYALNTFTNLVVQLIRNMEAEEVLEMQDLWLLRRSEKVTNWLQSNGWDR LKRMAVSGDDCVVKPIDDRFAHALRFLNDMGKVRKDTQEWKPSTGWDNWEEVPFCSHH FNKLHLKDGRSIVVPCRHQDELIGRARVSPGAGWSIRETACLAKSYAQMWQLLYFHRR DLRLMANAICSSVPVDWVPTGRTTWSIHGKGEWMTTEDMLVVWNRVWIEENDHMEDKT PVAKWTDIPYLGKREDLWCGSLIGHRPRTTWAENIKNTVNMVRRIIGDEEKYMDYLST QVRYLGEEGSTPGVL" ORIGIN 1 gacagttcga gtttgaagcg aaagctagca acagtatcaa caggttttat tttggatttg 61 gaaacgagag tttctggtca tgaaaaaccc aaaaaagaaa tccggaggat tccggattgt 121 caatatgcta aaacgcggag tagcccgtgt gagccccttt gggggcttga agaggctgcc 181 agccggactt ctgctgggtc atgggcccat caggatggtc ttggcgattc tagccttttt 241 gagattcacg gcaatcaagc catcactggg tctcatcaat agatggggtt cagtggggaa 301 aaaagaggct atggaaataa taaagaagtt caagaaagat ctggctgcca tgctgagaat 361 aatcaatgct aggaaggaga agaagagacg aggcgcagaa actagtgtcg gaattgttgg 421 cctcctgctg accacagcta tggcagcgga ggtcactaga cgtgggagtg catactatat 481 gtacttggac agaaaagatg ctggggaggc catatctttt ccaaccacat tggggatgaa 541 taagtgttat atacagatca tggatcttgg acacatgtgt gatgccacca tgagctatga 601 atgccctatg ctggatgagg gggtggaacc agatgacgtc gattgttggt gcaacacgac 661 gtcaacttgg gttgtgtacg gaacctgcca tcacaaaaaa ggtgaagcac ggagatctag 721 aagagccgtg acgctcccct cccattccac taggaagctg caaacgcggt cgcaaacctg 781 gttggaatca agagaataca caaagcactt gattagagtc gaaaattgga tattcaggaa 841 ccctggtttc gctttagcag cagctgccat cgcttggctt ttgggaagct caacgagcca 901 aaaagtcata tacttggtca tgatactgct gattgccccg gcatacagca tcaggtgcat 961 aggagtcagc aatagggact ttgtggaagg tatgtcaggt gggacttggg ttgatgttgt 1021 cttggaacat ggaggttgtg tcaccgtaat ggcacaggac aaaccgactg tcgacataga 1081 gctggttaca acaacagtca gcaacatggc ggaggtaaga tcctactgct atgaggcatc 1141 aatatcagac atggcttcgg acagccgctg cccaacacaa ggtgaagcct accttgacaa 1201 gcaatcagac actcaatatg tttgcaaaag aacgttagtg gacagaggct ggggaaatgg 1261 atgtggactt tttggcaaag ggagcctggt gacatgcgct aagtttgcat gctccaagaa 1321 aatgaccggg aagagcatcc agccagagaa tctggagtac cggataatgt tgtcagttca 1381 tggctcccag cacagtggga tgatcgttaa tgacacagga catgaaactg atgagaatag 1441 agcgaaggtt gagataacgc ccaattcacc aagagccgaa gccaccctgg ggggttttgg 1501 aagcctagga cttgattgtg aaccgaggac aggccttgac ttttcagatt tgtattactt 1561 gactatgaat aacaagcact ggttggttca caaggagtgg ttccacgaca ttccattacc 1621 ttggcacgct ggggcagaca ccggaactcc acactggaac aacaaagaag cactggtaga 1681 gttcaaggac gcacatgcca aaaggcaaac tgtcgtggtt ctagggagtc aagaaggagc 1741 agttcacacg gcccttgctg gagctctgga ggctgagatg gatggtgcaa agggaaggct 1801 gtcctctggc cacttgaaat gtcgcctgaa aatggataaa cttagattga agggcgtgtc 1861 atactccttg tgtaccgcag cgttcacatt caccaagatc ccggctgaaa cactgcacgg 1921 gacagtcaca gtggaggtac agtacgcagg gacagatgga ccttgcaagg ttccagctca 1981 gatggcggtg gacatgcaaa ctctgacccc agttgggagg ttgataaccg ctaaccccgt 2041 aatcactgaa agcactgaga actctaagat gatgctggaa cttgatccac catttgggga 2101 ctcttacatt gtcataggag tcggggagaa gaagatcacc caccactggc ataggagtgg 2161 cagcaccatt ggaaaagcat ttgaagccac tgtgagaggt gccaagagaa tggcagtctt 2221 gggagacaca gcctgggact ttggatcagt tggaggcgct ctcaactcat tgggcaaggg 2281 catccatcaa atttttggag cagctttcaa atcattgttt ggaggaatgt cctggttctc 2341 acaaattctc attggaacgt tgctgatgtg gttgggtctg aacacaaaga atggatctat 2401 ttcccttatg tgcttggcct tagggggagt gttgatcttc ttatccacag ccgtctctgc 2461 tgatgtgggg tgctcggtgg acttctcaaa gaaggagacg agatgtggta caggggtgtt 2521 cgtctataac gacgttgaag cctggaggga caggtacaag taccatcctg actccccccg 2581 tagattggca gcagcagtca agcaagcctg ggaagatggt atctgcggga tctcctctgt 2641 ttcaagaatg gaaaacatca tgtggagatc agtagaaggg gagctcaacg caatcctgga 2701 agagaatgga gttcaactga cggtcgttgt gggatctgta aaaaacccca tgtggagagg 2761 tccacagaga ttgcccgtgc ctgtgaacga gctgccccac ggctggaagg cttgggggaa 2821 atcgtacttc gtcagagcag caaagacaaa taacagcttt gtcgtggatg gtgacacact 2881 gaaggaatgc ccactcaaac atagagcatg gaacagcttt cttgtggagg atcatgggtt 2941 cggggtattt cacactagtg tctggctcaa ggttagagaa gattattcat tagagtgtga 3001 tccagccgtt attggaacag ctgttaaggg aaaggaggct gtacacagtg atctaggcta 3061 ctggattgag agtgagaaga atgacacatg gaggctgaag agggcccatc tgatcgagat 3121 gaaaacatgt gaatggccaa agtcccacac attgtggaca gatggaatag aagagagtga 3181 tctgatcata cccaagtctt tagctgggcc actcagccat cacaatacca gagagggcta 3241 caggacccaa atgaaagggc catggcacag tgaagagctt gaaattcggt ttgaggaatg 3301 cccaggcact aaggtccacg tggaggaaac atgtggaaca agaggaccat ctctgagatc 3361 aaccactgca agcggaaggg tgatcgagga atggtgctgc agggagtgca caatgccccc 3421 actgtcgttc tgggctaaag atggctgttg gtatggaatg gagataaggc ccaggaaaga 3481 accagaaagc aacttagtaa ggtcaatggt gactgcagga tcaactgatc acatggatca 3541 cttctccctt ggagtgcttg tgattctgct catggtgcag gaagggctga agaagagaat 3601 gaccacaaag atcatcataa gcacatcaat ggcagtgctg gtagctatga tcctgggagg 3661 attttcaatg agtgacctgg ctaagcttgc aattttgatg ggtgccacct tcgcggaaat 3721 gaacactgga ggagatgtag ctcatctggc gctgatagcg gcattcaaag tcagaccagc 3781 gttgctggta tctttcatct tcagagctaa ttggacaccc cgtgaaagca tgctgctggc 3841 cttggcctcg tgtcttttgc aaactgcgat ctccgccttg gagggcgacc tgatggttct 3901 catcaatggt tttgctttgg cctggttggc aatacgagcg atggttgttc cacgcactga 3961 caacatcacc ttggcaatcc tggctgctct gacaccactg gcccggggca cactgcttgt 4021 ggcgtggaga gcaggccttg ctacttgcgg ggggtttatg ctcctctctc tgaagggaaa 4081 aggcagtgtg aagaagaact taccatttgt catggccctg ggactaaccg ctgtgaggct 4141 ggtcgacccc atcaacgtgg tgggactgct gttgctcaca aggagtggga agcggagctg 4201 gccccctagc gaagtactca cagctgttgg cctgatatgc gcattggctg gagggttcgc 4261 caaggcagat atagagatgg ctgggcccat ggccgcggtc ggtctgctaa ttgtcagtta 4321 cgtggtctca ggaaagagtg tggacatgta cattgaaaga gcaggtgaca tcacatggga 4381 aaaagatgcg gaagtcactg gaaacagtcc ccggctcgat gtggcgctag atgagagtgg 4441 tgatttctcc ctggtggagg atgacggtcc ccccatgaga gagatcatac tcaaggtggt 4501 cctgatgacc atctgtggca tgaacccaat agccataccc tttgcagctg gagcgtggta 4561 cgtatacgtg aagactggaa aaaggagtgg tgctctatgg gatgtgcctg ctcccaagga 4621 agtaaaaaag ggggagacca cagatggagt gtacagagta atgactcgta gactgctagg 4681 ttcaacacaa gttggagtgg gagttatgca agagggggtc tttcacacta tgtggcacgt 4741 cacaaaagga tccgcgctga gaagcggtga agggagactt gatccatact ggggagatgt 4801 caagcaggat ctggtgtcat actgtggtcc atggaagcta gatgccgcct gggacgggca 4861 cagcgaggtg cagctcttgg ccgtgccccc cggagagaga gcgaggaaca tccagactct 4921 gcccggaata tttaagacaa aggatgggga cattggagcg gttgcgctgg attacccagc 4981 aggaacttca ggatctccaa tcctagacaa gtgtgggaga gtgataggac tttatggcaa 5041 tggggtcgtg atcaaaaatg ggagttatgt tagtgccatc acccaaggga ggagggagga 5101 agagactcct gttgagtgct tcgagccttc gatgctgaag aagaagcagc taactgtctt 5161 agacttgcat cctggagctg ggaaaaccag gagagttctt cctgaaatag tccgtgaagc 5221 cataaaaaca agactccgta ctgtgatctt agctccaacc agggttgtcg ctgctgaaat 5281 ggaggaagcc cttagagggc ttccagtgcg ttatatgaca acagcagtca atgtcaccca 5341 ctctggaaca gaaatcgtcg acttaatgtg ccatgccacc ttcacttcac gtctactaca 5401 gccaatcaga gtccccaact ataatctgta tattatggat gaggcccact tcacagatcc 5461 ctcaagtata gcagcaagag gatacatttc aacaagggtt gagatgggcg aggcggctgc 5521 catcttcatg accgccacgc caccaggaac ccgtgacgca tttccggact ccaactcacc 5581 aattatggac accgaagtgg aagtcccaga gagagcctgg agctcaggct ttgattgggt 5641 gacggatcat tctggaaaaa cagtttggtt tgttccaagc gtgaggaacg gcaatgagat 5701 cgcagcttgt ctgacaaagg ctggaaaacg ggtcatacag ctcagcagaa agacttttga 5761 gacagagttc cagaaaacaa aacatcaaga gtgggacttt gtcgtgacaa ctgacatttc 5821 agagatgggc gccaacttta aagctgaccg tgtcatagat tccaggagat gcctaaagcc 5881 ggtcatactt gatggcgaga gagtcattct ggctggaccc atgcctgtca cacatgccag 5941 cgctgcccag aggagggggc gcataggcag gaatcccaat aaacctggag atgagtatct 6001 gtatggaggt gggtgcgcag agactgacga agaccatgca cactggcttg aagcaagaat 6061 gctccttgac aatatttacc tccaagatgg cctcatagcc tcgctctatc gacctgaggc 6121 cgacaaagta gcagccattg agggagagtt caagcttagg acggagcaaa ggaagacctt 6181 tgtggaactc atgaaaagag gagatcttcc tgtttggctg gcctatcagg ttgcatctgc 6241 cggaataacc tacacagata gaagatggtg ctttgatggc acgaccaaca acaccataat 6301 ggaagacagt gtgccggcag aggtgtggac cagacacgga gagaaaagag tgctcaaacc 6361 gaggtggatg gacgccagag tttgttcaga tcatgcggcc ctgaagtcat tcaaggagtt 6421 tgccgctggg aaaagaggag cggcttttgg agtgatggaa gccctgggaa cactgccagg 6481 acacatgaca gagagattcc aggaagccat tgacaacctc gctgtgctca tgcgggcaga 6541 gactggaagc aggccttaca aagccgcggc ggcccaattg ccggagaccc tagagaccat 6601 tatgcttttg gggttgctgg gaacagtctc gctgggaatc tttttcgtct tgatgaggaa 6661 caagggcata gggaagatgg gctttggaat ggtgactctt ggggccagcg catggctcat 6721 gtggctctcg gaaattgagc cagccagaat tgcatgtgtc ctcattgttg tgttcctatt 6781 gctggtggtg ctcatacctg agccagaaaa gcaaagatct ccccaggaca accaaatggc 6841 aatcatcatc atggtagcag taggtcttct gggcttgatt accgccaatg aactcggatg 6901 gttggagaga acaaagagtg acctaagcca tctaatggga aggagagagg agggggcaac 6961 cataggattc tcaatggaca ttgacctgcg gccagcctca gcttgggcca tctatgctgc 7021 cttgacaact ttcattaccc cagccgtcca acatgcagtg accacttcat acaacaacta 7081 ctccttaatg gcgatggcca cgcaagctgg agtgttgttt ggtatgggca aagggatgcc 7141 attctacgca tgggactttg gagtcccgct gctaatgata ggttgctact cacaattaac 7201 acccctgacc ctaatagtgg ccatcatttt gctcgtggcg cactacatgt acttgatccc 7261 agggctgcag gcagcagctg cgcgtgctgc ccagaagaga acggcagctg gcatcatgaa 7321 gaaccctgtt gtggatggaa tagtggtgac tgacattgac acaatgacaa ttgaccccca 7381 agtggagaaa aagatgggac aggtgctact catagcagta gccgtctcca gcgccatact 7441 gtcgcggacc gcctgggggt ggggggaggc tggggccctg atcacagccg caacttccac 7501 tttgtgggaa ggctctccga acaagtactg gaactcctct acagccactt cactgtgtaa 7561 catttttagg ggaagttact tggctggagc ttctctaatc tacacagtaa caagaaacgc 7621 tggcttggtc aagagacgtg ggggtggaac aggagagacc ctgggagaga aatggaaggc 7681 ccgcttgaac cagatgtcgg ccctggagtt ctactcctac aaaaagtcag gcatcaccga 7741 ggtgtgcaga gaagaggccc gccgcgccct caaggacggt gtggcaacgg gaggccatgc 7801 tgtgtcccga ggaagtgcaa agctgagatg gctggtggag cggggatacc tgcagcccta 7861 tggaaaggtc attgatcttg gatgtggcag agggggctgg agttactacg ccgccaccat 7921 ccgcaaagtt caagaagtga aaggatacac aaaaggaggc cctggtcatg aagaacccgt 7981 gttggtgcaa agctatgggt ggaacatagt ccgtcttaag agtggggtgg acgtctttca 8041 tatggcggct gagccgtgtg acacgttgct gtgtgacata ggtgagtcat catctagtcc 8101 tgaagtggaa gaagcacgga cgctcagagt cctctccatg gtgggggatt ggcttgaaaa 8161 aagaccagga gccttttgta taaaagtgtt gtgcccatac accagcacta tgatggaaac 8221 cctggagcga ctgcagcgta ggtatggggg aggactggtc agagtgccac tctcccgcaa 8281 ctctacacat gagatgtact gggtctctgg agcgaaaagc aacaccataa aaagtgtgtc 8341 caccacgagc cagctcctct tggggcgcat ggacgggcct aggaggccag tgaaatatga 8401 ggaggatgtg aatctcggct ctggcacgcg ggctgtggta agctgcgctg aagctcccaa 8461 catgaagatc attggtaacc gcattgaaag gatccgcagt gagcacgcgg aaacgtggtt 8521 ctttgacgag aaccacccat ataggacatg ggcttaccat ggaagctatg aggcccccac 8581 acaagggtca gcgtcctctc taataaacgg ggttgtcagg ctcctgtcaa aaccctggga 8641 tgtggtgact ggagtcacag gaatagccat gaccgacacc acaccgtatg gtcagcaaag 8701 agttttcaag gaaaaagtgg acactagggt gccagacccc caagaaggca ctcgtcaggt 8761 tatgagcatg gtctcttcct ggttgtggaa agagctaggc aaacacaaac ggccacgagt 8821 ctgtaccaaa gaagagttca tcaacaaggt tcgtagcaat gcagcattag gggcaatatt 8881 tgaagaggaa aaagagtgga agactgcagt ggaagctgtg aacgatccaa ggttctgggc 8941 tctagtggac aaggaaagag agcaccacct gagaggagag tgccagagtt gtgtgtacaa 9001 catgatggga aaaagagaaa agaaacaagg ggaatttgga aaggccaagg gcagccgcgc 9061 catctggtat atgtggctag gggctagatt tctagagttc gaagcccttg gattcttgaa 9121 cgaggatcac tggatgggga gagagaactc aggaggtggt gttgaagggc tgggattaca 9181 aagactcgga tatgtcctag aagagatgag tcgcatacca ggaggaagga tgtatgcaga 9241 tgacactgct ggctgggaca cccgcattag caggtttgat ctggagaatg aagctctaat 9301 caccaaccaa atggagaaag ggcacagggc cttggcattg gccataatca agtacacata 9361 ccaaaacaaa gtggtaaagg tccttagacc agctgaaaaa gggaaaacag ttatggacat 9421 tatttcgaga caagaccaaa gggggagcgg acaagttgtc acttacgctc ttaacacatt 9481 taccaaccta gtggtgcaac tcattcggaa tatggaggct gaggaagttc tagagatgca 9541 agacttgtgg ctgctgcgga ggtcagagaa agtgaccaac tggttgcaga gcaacggatg 9601 ggataggctc aaacgaatgg cagtcagtgg agatgaytgc gttgtgaagc caattgatga 9661 taggtttgca catgccctca ggttcttgaa tgatatggga aaagttagga aggacacaca 9721 agagtggaaa ccctcaactg gatgggacaa ctgggaagaa gttccgtttt gctcccacca 9781 cttcaacaag ctccatctca aggacgggag gtccattgtg gttccctgcc gccaccaaga 9841 tgaactgatt ggccgggccc gcgtctctcc aggggcggga tggagcatcc gggagactgc 9901 ttgcctagca aaatcatatg cgcaaatgtg gcagctcctt tatttccaca gaagggacct 9961 ccgactgatg gccaatgcca tttgttcatc tgtgccagtt gactgggttc caactgggag 10021 aactacctgg tcaatccatg gaaagggaga atggatgacc actgaagaca tgcttgtggt 10081 gtggaacaga gtgtggattg aggagaacga ccacatggaa gacaagaccc cagttgcgaa 10141 atggacagac attccctatt tgggaaaaag ggaagacttg tggtgtggat ctctcatagg 10201 gcacagaccg cgcaccacct gggctgagaa cattaaaaac acagtcaaca tggtgcgcag 10261 gatcataggt gatgaagaaa agtacatgga ctacctatcc acccaagttc gctacttggg 10321 cgaagaaggg tctacacctg gagtgctgta agcaccaatc ttaatgttgt caggcctgct 10381 agtcagccac agcttgggga aagctgtgca gcctgtgacc cccccaggag aagctgggaa 10441 accaagccta tagtcaggcc gagaacgcca tggcacggaa gaagccatgc tgcctgtgag 10501 cccctcagag gacactgagt caaaaaaccc cacgcgcttg gaggcgcagg atgggaaaag 10561 aaggtggcga ccttccccac ccttcaatct ggggcctgaa ctggagat

Sequences producing significant alignments: Select:AllNone Selected:0 AlignmentsDownloadGenBankGraphicsDistance tree of resultsShow/hide columns of the table presenting sequences producing significant alignments Sequences producing significant alignments: Select for downloading or viewing reports Description Max score Total score Query cover E value Ident Accession Select seq gb|KY317938.1| Zika virus isolate ZIKV/Homo_sapiens/Colombia/2016/ZC199Se polyprotein gene, complete cds 18969 18969 100% 0.0 100% KY317938.1 Select seq gb|KX198135.2| Zika virus strain ZIKV/Homo sapiens/PAN/BEI-259634_V4/2016, complete genome 18925 18925 100% 0.0 99% KX198135.2 Select seq gb|KY317939.1| Zika virus isolate ZIKV/Homo_sapiens/Colombia/2016/ZC204Se polyprotein gene, complete cds 18921 18921 100% 0.0 99% KY317939.1 Select seq gb|KY014303.1| Zika virus isolate Zika virus/H.sapiens-wt/DOM/2016/BB-0127-SER polyprotein gene, complete cds 18920 18920 100% 0.0 99% KY014303.1 Select seq gb|KY317940.1| Zika virus isolate ZIKV/Homo_sapiens/Colombia/2016/ZC207Se polyprotein gene, complete cds 18914 18914 100% 0.0 99% KY317940.1 Select seq gb|KX156776.2| Zika virus strain ZIKV/Homo sapiens/PAN/CDC-259364_V1-V2/2015, complete genome 18914 18914 100% 0.0 99% KX156776.2 Select seq gb|KY317936.1| Zika virus isolate ZIKV/Homo_sapiens/Colombia/2016/ZC188Se polyprotein gene, complete cds 18908 18908 100% 0.0 99% KY317936.1 Select seq gb|KX156774.2| Zika virus strain ZIKV/Homo sapiens/PAN/CDC-259359_V1-V3/2015, complete genome 18908 18908 100% 0.0 99% KX156774.2 Select seq gb|KX156775.2| Zika virus strain ZIKV/Homo sapiens/PAN/CDC-259249_V1-V3/2015, complete genome 18903 18903 100% 0.0 99% KX156775.2 Select seq gb|KX087102.2| Zika virus strain ZIKV/Homo sapiens/COL/FLR/2015, complete genome 18903 18903 100% 0.0 99% KX087102.2 Select seq gb|KU820897.5| Zika virus isolate FLR polyprotein gene, complete cds 18903 18903 100% 0.0 99% KU820897.5 Select seq gb|KX247646.1| Zika virus isolate Zika virus/Homo sapiens/COL/UF-1/2016, complete genome 18903 18903 100% 0.0 99% KX247646.1 Select seq gb|KU647676.1| Zika virus strain MRS_OPY_Martinique_PaRi_2015 polyprotein gene, complete cds 18897 18897 100% 0.0 99% KU647676.1 Select seq gb|KY317937.1| Zika virus isolate ZIKV/Homo_sapiens/Colombia/2016/ZC192Se polyprotein gene, complete cds 18881 18881 100% 0.0 99% KY317937.1 Select seq gb|KU922960.1| Zika virus isolate MEX/InDRE/Sm/2016, complete genome 18875 18875 100% 0.0 99% KU922960.1 Select seq gb|KX893855.1| Zika virus strain Zika virus/Homo sapiens/VEN/UF-2/2016, complete genome 18873 18873 100% 0.0 99% KX893855.1 Select seq gb|KX702400.1| Zika virus strain Zika virus/Homo sapiens/VEN/UF-1/2016, complete genome 18870 18870 100% 0.0 99% KX702400.1 Select seq gb|KX548902.1| Zika virus isolate ZIKV/COL/FCC00093/2015 polyprotein gene, complete cds 18870 18870 100% 0.0 99% KX548902.1 Select seq gb|KU922923.1| Zika virus isolate MEX/InDRE/Lm/2016, complete genome 18870 18870 100% 0.0 99% KU922923.1 Select seq gb|KX447510.1| Zika virus isolate 1_0049_PF polyprotein gene, complete cds 18848 18848 100% 0.0 99% KX447510.1 Select seq gb|KU991811.1| Zika virus isolate Brazil/2016/INMI1 polyprotein gene, complete cds 18842 18842 100% 0.0 99% KU991811.1 Select seq gb|KY075932.1| Zika virus isolate ZIKV/Homo_sapiens/USA/2016/FL001Sa polyprotein gene, complete cds 18836 18836 100% 0.0 99% KY075932.1 Select seq gb|KX447512.1| Zika virus isolate 1_0181_PF polyprotein gene, complete cds 18836 18836 100% 0.0 99% KX447512.1 Select seq gb|KX369547.1| Zika virus strain PF13/251013-18, complete genome 18836 18836 100% 0.0 99% KX369547.1 Select seq gb|KU509998.3| Zika virus strain Haiti/1225/2014, complete genome 18836 18836 100% 0.0 99% KU509998.3 Select seq gb|KJ776791.2| Zika virus strain H/PF/2013, complete genome 18831 18831 100% 0.0 99% KJ776791.2 Select seq gb|KX447509.1| Zika virus isolate 1_0087_PF polyprotein gene, complete cds 18831 18831 100% 0.0 99% KX447509.1 Select seq gb|KX280026.1| Zika virus isolate Paraiba_01, complete genome 18831 18831 100% 0.0 99% KX280026.1 Select seq gb|KX447513.1| Zika virus isolate 1_0134_PF polyprotein gene, complete cds 18825 18825 100% 0.0 99% KX447513.1 Select seq gb|KR872956.1| Zika virus strain 17829 polyprotein gene, complete cds 18820 18820 100% 0.0 99% KR872956.1 Select seq gb|KX197205.1| Zika virus isolate 9, complete genome 18820 18820 100% 0.0 99% KX197205.1 Select seq gb|KX447515.1| Zika virus isolate 1_0030_PF polyprotein gene, complete cds 18820 18820 100% 0.0 99% KX447515.1 Select seq gb|KX447511.1| Zika virus isolate 1_0015_PF polyprotein gene, complete cds 18820 18820 100% 0.0 99% KX447511.1 Select seq gb|KU321639.1| Zika virus strain ZikaSPH2015, complete genome 18820 18820 100% 0.0 99% KU321639.1 Select seq gb|KX447514.1| Zika virus isolate 1_0035_PF polyprotein gene, complete cds 18814 18814 100% 0.0 99% KX447514.1 Select seq gb|KX051563.1| Zika virus isolate Haiti/1/2016, complete genome 18814 18814 100% 0.0 99% KX051563.1 Select seq gb|KX811222.1| Zika virus isolate Brazil_2015_MG, complete genome 18809 18809 100% 0.0 99% KX811222.1 Select seq gb|KX447516.1| Zika virus isolate 1_0111_PF polyprotein gene, complete cds 18809 18809 100% 0.0 99% KX447516.1 Select seq gb|KU729218.1| Zika virus isolate BeH828305 polyprotein gene, complete cds 18809 18809 100% 0.0 99% KU729218.1 Select seq gb|KU707826.1| Zika virus isolate SSABR1, complete genome 18809 18809 100% 0.0 99% KU707826.1 Select seq gb|KU365779.1| Zika virus strain BeH819966 polyprotein gene, complete cds 18809 18809 100% 0.0 99% KU365779.1 Select seq gb|KX262887.1| Zika virus isolate 103451, complete genome 18803 18803 100% 0.0 99% KX262887.1 Select seq gb|KX197192.1| Zika virus isolate ZIKV/H.sapiens/Brazil/PE243/2015, complete genome 18803 18803 100% 0.0 99% KX197192.1 Select seq gb|KU497555.1| Zika virus isolate Brazil-ZKV2015, complete genome 18800 18800 99% 0.0 99% KU497555.1 Select seq gb|KX694534.2| Zika virus strain ZIKV/Homo sapiens/HND/R103451/2015, complete genome 18792 18792 100% 0.0 99% KX694534.2 Select seq gb|KX879604.1| Zika virus isolate SN089, complete genome 18792 18792 100% 0.0 99% KX879604.1 Select seq gb|KU758877.1| Zika virus isolate 17271 polyprotein gene, complete cds 18792 18792 100% 0.0 99% KU758877.1 Select seq gb|KU940228.1| Zika virus isolate Bahia07, partial genome 18792 18792 100% 0.0 99% KU940228.1 Select seq gb|KU926309.1| Zika virus isolate Rio-U1, complete genome 18792 18792 100% 0.0 99% KU926309.1 Select seq gb|KU365780.1| Zika virus strain BeH815744 polyprotein gene, complete cds 18792 18792 100% 0.0 99% KU365780.1 Select seq gb|KY014297.1| Zika virus isolate Zika virus/H.sapiens-wt/BRA/2016/FC-6864-URI polyprotein gene, complete cds 18790 18790 100% 0.0 99% KY014297.1 Select seq gb|KU365777.1| Zika virus strain BeH818995 polyprotein gene, complete cds 18787 18787 100% 0.0 99% KU365777.1 Select seq gb|KY328289.1| Zika virus isolate HN16, complete genome 18781 18781 100% 0.0 99% KY328289.1 Select seq gb|KX879603.1| Zika virus isolate SN062, complete genome 18781 18781 100% 0.0 99% KX879603.1 Select seq gb|KU501217.1| Zika virus strain 8375 polyprotein gene, complete cds 18781 18781 100% 0.0 99% KU501217.1 Select seq gb|KU365778.1| Zika virus strain BeH819015 polyprotein gene, complete cds 18781 18781 100% 0.0 99% KU365778.1 Select seq gb|KU312312.1| Zika virus isolate Z1106033 polyprotein gene, complete cds 18781 18781 100% 0.0 99% KU312312.1 Select seq gb|KU729217.2| Zika virus isolate BeH823339 polyprotein gene, complete cds 18776 18776 100% 0.0 99% KU729217.2 Select seq gb|KU527068.1| Zika virus strain Natal RGN, complete genome 18776 18776 100% 0.0 99% KU527068.1 Select seq gb|KU501216.1| Zika virus strain 103344 polyprotein gene, complete cds 18776 18776 100% 0.0 99% KU501216.1 Select seq gb|KY014327.1| Zika virus isolate Zika virus/H.sapiens-wt/HND/2016/HU-ME167-PLA polyprotein gene, complete cds 18772 18772 100% 0.0 99% KY014327.1 Select seq gb|KY120348.1| Zika virus isolate CIENI551, complete genome 18770 18770 100% 0.0 99% KY120348.1 Select seq gb|KX447517.1| Zika virus isolate 1_0038_PF polyprotein gene, complete cds 18770 18770 100% 0.0 99% KX447517.1 Select seq gb|KX520666.1| Zika virus isolate HS-2015-BA-01 polyprotein gene, complete cds 18770 18770 100% 0.0 99% KX520666.1 Select seq gb|KX247632.1| Zika virus isolate MEX_I_7 polyprotein gene, complete cds 18770 18770 100% 0.0 99% KX247632.1 Select seq gb|KU937936.1| Zika virus isolate ZIKVNL00013 polyprotein gene, complete cds 18770 18770 100% 0.0 99% KU937936.1 Select seq gb|KU501215.1| Zika virus strain PRVABC59, complete genome 18770 18770 100% 0.0 99% KU501215.1 Select seq gb|KX269878.1| Zika virus isolate Haiti/2016/PD, complete genome 18766 18766 100% 0.0 99% KX269878.1 Select seq gb|KX087101.3| Zika virus strain ZIKV/Homo sapiens/PRI/PRVABC59/2015, complete genome 18764 18764 100% 0.0 99% KX087101.3 Select seq gb|KY014315.1| Zika virus isolate Zika virus/H.sapiens-wt/HND/2016/HU-ME152-SER polyprotein gene, complete cds 18764 18764 100% 0.0 99% KY014315.1 Select seq gb|KY014304.1| Zika virus isolate Zika virus/H.sapiens-wt/DOM/2016/BB-0180-SER polyprotein gene, complete cds 18764 18764 100% 0.0 99% KY014304.1 Select seq gb|KX601168.1| Zika virus strain ZIKV/Homo Sapiens/PRI/PRVABC59/2015, complete genome 18764 18764 100% 0.0 99% KX601168.1 Select seq gb|KX446951.2| Zika virus strain ZIKV/Aedes.sp/MEX/MEX_I-7/2016, complete genome 18759 18759 100% 0.0 99% KX446951.2 Select seq gb|KY014296.1| Zika virus isolate Zika virus/H.sapiens-wt/BRA/2016/FC-DQ131D1-URI polyprotein gene, complete cds 18759 18759 100% 0.0 99% KY014296.1 Select seq gb|KX806557.2| Zika virus isolate TS17-2016, complete genome 18759 18759 100% 0.0 99% KX806557.2 Select seq gb|KX856011.1| Zika virus strain ZIKV/Aedes sp./MEX_I-44/2016, complete genome 18759 18759 100% 0.0 99% KX856011.1 Select seq gb|KX377337.1| Zika virus strain PRVABC-59, complete genome 18759 18759 100% 0.0 99% KX377337.1 Select seq gb|KU926310.1| Zika virus isolate Rio-S1, complete genome 18759 18759 100% 0.0 99% KU926310.1 Select seq gb|KU820898.1| Zika virus isolate GZ01 polyprotein gene, complete cds 18759 18759 100% 0.0 99% KU820898.1 Select seq gb|KX446950.2| Zika virus strain ZIKV/Aedes.sp/MEX/MEX_2-81/2016, complete genome 18753 18753 100% 0.0 99% KX446950.2 Select seq gb|KU870645.1| Zika virus isolate FB-GWUH-2016, complete genome 18753 18753 100% 0.0 99% KU870645.1 Select seq gb|KY075939.1| Zika virus isolate ZIKV/Aedes_aegypti/USA/2016/FL08M polyprotein gene, complete cds 18748 18748 100% 0.0 99% KY075939.1 Select seq gb|KY075933.1| Zika virus isolate ZIKV/Homo_sapiens/USA/2016/FL008U polyprotein gene, complete cds 18748 18748 100% 0.0 99% KY075933.1 Select seq gb|KY003153.1| Zika virus strain ZIKV/34997/Pavia/2016 polyprotein gene, complete cds 18748 18748 100% 0.0 99% KY003153.1 Select seq gb|KU853013.1| Zika virus isolate Dominican Republic/2016/PD2, complete genome 18748 18748 100% 0.0 99% KU853013.1 Select seq gb|KU853012.1| Zika virus isolate Dominican Republic/2016/PD1, complete genome 18746 18746 100% 0.0 99% KU853012.1 Select seq gb|KY075934.1| Zika virus isolate ZIKV/Homo_sapiens/USA/2016/FL016U polyprotein gene, complete cds 18742 18742 100% 0.0 99% KY075934.1 Select seq gb|KY014300.1| Zika virus isolate Zika virus/H.sapiens-wt/DOM/2016/BB-0208-SER polyprotein gene, complete cds 18742 18742 100% 0.0 99% KY014300.1 Select seq dbj|LC190723.1| Zika virus genomic RNA, complete genome, strain: ZIKV/Hu/Yokohama/1/2016 18742 18742 100% 0.0 99% LC190723.1 Select seq gb|KX056898.1| Zika virus isolate Zika virus/GZ02/2016 polyprotein gene, complete cds 18742 18742 100% 0.0 99% KX056898.1 Select seq gb|KU955590.1| Zika virus isolate Z16019 polyprotein gene, complete cds 18742 18742 100% 0.0 99% KU955590.1 Select seq gb|KX766028.1| Zika virus isolate R114916, complete genome 18739 18739 100% 0.0 99% KX766028.1 Select seq gb|KY014321.1| Zika virus isolate Zika virus/H.sapiens-wt/DOM/2016/BB-0115-SER polyprotein gene, complete cds 18737 18737 100% 0.0 99% KY014321.1 Select seq gb|KU740184.2| Zika virus isolate GD01 polyprotein gene, complete cds 18737 18737 100% 0.0 99% KU740184.2 Select seq gb|KU761564.1| Zika virus isolate GDZ16001 polyprotein gene, complete cds 18737 18737 100% 0.0 99% KU761564.1 Select seq gb|KY014295.1| Zika virus isolate Zika virus/H.sapiens-wt/USA/2016/FL-010-URI polyprotein gene, complete cds 18731 18731 100% 0.0 99% KY014295.1 Select seq gb|KX922707.1| Zika virus isolate ZIKV/Homo_sapiens/USA/2016/FL039U polyprotein gene, complete cds 18731 18731 100% 0.0 99% KX922707.1 Select seq gb|KX842449.2| Zika virus isolate ZIKV/Homo_sapiens/USA/2016/FL010U polyprotein gene, complete cds 18731 18731 100% 0.0 99% KX842449.2 Select seq gb|KY120349.1| Zika virus isolate CIENI551, complete genome 18727 18727 100% 0.0 99% KY120349.1 Select seq gb|KY003154.1| Zika virus strain ZIKV/VR10599/Pavia/2016 polyprotein gene, complete cds 18726 18726 100% 0.0 99% KY003154.1

LOCUS KY317938 10387 bp RNA linear VRL 27-DEC-2016 DEFINITION Zika virus isolate ZIKV/Homo_sapiens/Colombia/2016/ZC199Se polyprotein gene, complete cds. ACCESSION KY317938 VERSION KY317938.1 KEYWORDS . SOURCE Zika virus ORGANISM Zika virus Viruses; ssRNA viruses; ssRNA positive-strand viruses, no DNA stage; Flaviviridae; Flavivirus. REFERENCE 1 (bases 1 to 10387) AUTHORS Grubaugh,N., Rogers,T., Beutler,N., Fredeking,T., Gangavarupu,K., Oliveira,G., Robles-Sikisaka,R., Burton,D. and Andersen,K. TITLE Zika virus sequenced from Colombia, 2016 JOURNAL Unpublished REFERENCE 2 (bases 1 to 10387) AUTHORS Grubaugh,N., Rogers,T., Beutler,N., Fredeking,T., Gangavarupu,K., Oliveira,G., Robles-Sikisaka,R., Burton,D. and Andersen,K. TITLE Direct Submission JOURNAL Submitted (09-DEC-2016) Department of Immunology and Microbial Science, The Scripps Research Institute, 10550 North Torrey Pines Road, IMM-210, La Jolla, CA 92037, USA COMMENT ##Assembly-Data-START## Assembly Method :: NovoAlign v. V3.04 Sequencing Technology :: Illumina ##Assembly-Data-END## FEATURES Location/Qualifiers source 1..10387 /organism="Zika virus" /mol_type="genomic RNA" /isolate="ZIKV/Homo_sapiens/Colombia/2016/ZC199Se" /isolation_source="serum" /host="Homo sapiens" /db_xref="taxon:64320" /country="Colombia" /collection_date="10-Jan-2016" /collected_by="Antibody Systems Inc" CDS 81..10352 /codon_start=1 /product="polyprotein" /protein_id="APQ41784.1" /translation="MKNPKKKSGGFRIVNMLKRGVARVSPFGGLKRLPAGLLLGHGPI RMVLAILAFLRFTAIKPSLGLINRWGSVGKKEAMEIIKKFKKDLAAMLRIINARKEKK RRGAETSVGIVGLLLTTAMAAEVTRRGSAYYMYLDRNDAGEAISFPTTLGMNKCYIQI MDLGHMCDATMSYECPMLDEGVEPDDVDCWCNTTSTWVVYGTCHHKKGEARRSRRAVT LPSHSTRKLQTRSQTWLESREYTKHLIRVENWIFRNPGFALAAAAIAWLLGSSTSQKV IYLVMILLIAPAYSIRCIGVSNRDFVEGMSGGTWVDVVLEHGGCVTVMAQDKPTVDIE LVTTTVSNMAEVRSYCYEASISDMASDSRCPTQGEAYLDKQSDTQYVCKRTLVDRGWG NGCGLFGKGSLVTCAKFACSKKMTGKSIQPENLEYRIMLSVHGSQHSGMIVNDTGHET DENRAKVEITPNSPRAEATLGGFGSLGLDCEPRTGLDFSDLYYLTMNNKHWLVHKEWF HDIPLPWHAGADTGTPHWNNKEALVEFKDAHAKRQTVVVLGSQEGAVHTALAGALEAE MDGAKGRLSSGHLKCRLKMDKLRLKGVSYSLCTAAFTFTKIPAETLHGTVTVEVQYAG TDGPCKVPAQMAVDMQTLTPVGRLITANPVITESTENSKMMLELDPPFGDSYIVIGVG EKKITHHWHRSGSTIGKAFEATVRGAKRMAVLGDTAWDFGSVGGALNSLGKGIHQIFG AAFKSLFGGMSWFSQILIGTLLMWLGLNTKNGSISLMCLALGGVLIFLSTAVSADVGC SVDFSKKETRCGTGVFVYNDVEAWRDRYKYHPDSPRRLAAAVKQAWEDGICGISSVSR MENIMWRSVEGELNAILEENGVQLTVVVGSVKNPMWRGPQRLPVPVNELPHGWKAWGK SYFVRAAKTNNSFVVDGDTLKECPLKHRAWNSFLVEDHGFGVFHTSVWLKVREDYSLE CDPAVIGTAVKGKEAVHSDLGYWIESEKNDTWRLKRAHLIEMKTCEWPKSHTLWTDGI EESDLIIPKSLAGPLSHHNTREGYRTQMKGPWHSEELEIRFEECPGTKVHVEETCGTR GPSLRSTTASGRVIEEWCCRECTMPPLSFWAKDGCWYGMEIRPRKEPESNLVRSMVTA GSTDHMDHFSLGVLVILLMVQEGLKKRMTTKIIISTSMAVLVAMILGGFSMSDLAKLA ILMGATFAEMNTGGDVAHLALIAAFKVRPALLVSFIFRANWTPRESMLLALASCLLQT AISALEGDLMVLINGFALAWLAIRAMVVPRTDNITLAILAALTPLARGTLLVAWRAGL ATCGGFMLLSLKGKGSVKKNLPFVMALGLTAVRLVDPINVVGLLLLTRSGKRSWPPSE VLTAVGLICALAGGFAKADIEMAGPMAAVGLLIVSYVVSGKSVDMYIERAGDITWEKD AEVTGNSPRLDVALDESGDFSLVEDDGPPMREIILKVVLMTICGMNPIAIPFAAGAWY VYVKTGKRSGALWDVPAPKEVKKGETTDGVYRVMTRRLLGSTQVGVGVMQEGVFHTMW HVTKGSALRSGEGRLDPYWGDVKQDLVSYCGPWKLDAAWDGHSEVQLLAVPPGERARN IQTLPGIFKTKDGDIGAVALDYPAGTSGSPILDKCGRVIGLYGNGVVIKNGSYVSAIT QGRREEETPVECFEPSMLKKKQLTVLDLHPGAGKTRRVLPEIVREAIKTRLRTVILAP TRVVAAEMEEALRGLPVRYMTTAVNVTHSGTEIVDLMCHATFTSRLLQPIRVPNYNLY IMDEAHFTDPSSIAARGYISTRVEMGEAAAIFMTATPPGTRDAFPDSNSPIMDTEVEV PERAWSSGFDWVTDHSGKTVWFVPSVRNGNEIAACLTKAGKRVIQLSRKTFETEFQKT KHQEWDFVVTTDISEMGANFKADRVIDSRRCLKPVILDGERVILAGPMPVTHASAAQR RGRIGRNPNKPGDEYLYGGGCAETDEDHAHWLEARMLLDNIYLQDGLIASLYRPEADK VAAIEGEFKLRTEQRKTFVELMKRGDLPVWLAYQVASAGITYTDRRWCFDGTTNNTIM EDSVPAEVWTRHGEKRVLKPRWMDARVCSDHAALKSFKEFAAGKRGAAFGVMEALGTL PGHMTERFQEAIDNLAVLMRAETGSRPYKAAAAQLPETLETIMLLGLLGTVSLGIFFV LMRNKGIGKMGFGMVTLGASAWLMWLSEIEPARIACVLIVVFLLLVVLIPEPEKQRSP QDNQMAIIIMVAVGLLGLITANELGWLERTKSDLSHLMGRREEGATIGFSMDIDLRPA SAWAIYAALTTFITPAVQHAVTTSYNNYSLMAMATQAGVLFGMGKGMPFYAWDFGVPL LMIGCYSQLTPLTLIVAIILLVAHYMYLIPGLQAAAARAAQKRTAAGIMKNPVVDGIV VTDIDTMTIDPQVEKKMGQVLLIAVAVSSAILSRTAWGWGEAGALITAATSTLWEGSP NKYWNSSTATSLCNIFRGSYLAGASLIYTVTRNAGLVKRRGGGTGETLGEKWKARLNQ MSALEFYSYKKSGITEVCREEARRALKDGVATGGHAVSRGSAKLRWLVERGYLQPYGK VIDLGCGRGGWSYYAATIRKVQEVKGYTKGGPGHEEPVLVQSYGWNIVRLKSGVDVFH MAAEPCDTLLCDIGESSSSPEVEEARTLRVLSMVGDWLEKRPGAFCIKVLCPYTSTMM ETLERLQRRYGGGLVRVPLSRNSTHEMYWVSGAKSNTIKSVSTTSQLLLGRMDGPRRP VKYEEDVNLGSGTRAVVSCAEAPNMKIIGNRIERIRSEHAETWFFDENHPYRTWAYHG SYEAPTQGSASSLINGVVRLLSKPWDVVTGVTGIAMTDTTPYGQQRVFKEKVDTRVPD PQEGTRQVMSMVSSWLWKELGKHKRPRVCTKEEFINKVRSNAALGAIFEEEKEWKTAV EAVNDPRFWALVDKEREHHLRGECQSCVYNMMGKREKKQGEFGKAKGSRAIWYMWLGA RFLEFEALGFLNEDHWMGRENSGGGVEGLGLQRLGYVLEEMSRIPGGRMYADDTAGWD TRISRFDLENEALITNQMEKGHRALALAIIKYTYQNKVVKVLRPAEKGKTVMDIISRQ DQRGSGQVVTYALNTFTNLVVQLIRNMEAEEVLEMQDLWLLRRSEKVTNWLQSNGWDR LKRMAVSGDDCVVKPIDDRFAHALRFLNDMGKVRKDTQEWKPSTGWDNWEEVPFCSHH FNKLHLKDGRSIVVPCRHQDELIGRARVSPGAGWSIRETACLAKSYAQMWQLLYFHRR DLRLMANAICSSVPVDWVPTGRTTWSIHGKGEWMTTEDMLVVWNRVWIEENDHMEDKT PVAKWTDIPYLGKREDLWCGSLIGHRPRTTWAENIKNTVNMVRRIIGDEEKYMDYLST QVRYLGEEGSTPGVL" ORIGIN 1 cgacagttcg agtttgaagc gaaagctagc aacagtatca acaggtttta ttttggattt 61 ggaaacgaga gtttctggtc atgaaaaacc caaaaaagaa atccggagga ttccggattg 121 tcaatatgct aaaacgcgga gtagcccgtg tgagcccctt tgggggcttg aagaggctgc 181 cagccggact tctgctgggt catgggccca tcaggatggt cttggcgatt ctagcctttt 241 tgagattcac ggcaatcaag ccatcactgg gtctcatcaa tagatggggt tcagtgggga 301 aaaaagaggc tatggaaata ataaagaagt tcaagaaaga tctggctgcc atgctgagaa 361 taatcaatgc taggaaggag aagaagagac gaggcgcaga aactagtgtc ggaattgttg 421 gcctcctgct gaccacagct atggcagcgg aggtcactag acgtgggagt gcatactata 481 tgtacttgga cagaaacgat gctggggagg ccatatcttt tccaaccaca ttggggatga 541 ataagtgtta tatacagatc atggatcttg gacacatgtg tgatgccacc atgagctatg 601 aatgccctat gctggatgag ggggtggaac cagatgacgt cgattgttgg tgcaacacga 661 cgtcaacttg ggttgtgtac ggaacctgcc atcacaaaaa aggtgaagca cggagatcta 721 gaagagccgt gacgctcccc tcccattcca ctaggaagct gcaaacgcgg tcgcaaacct 781 ggttggaatc aagagaatac acaaagcact tgattagagt cgaaaattgg atattcagga 841 accctggttt cgctttagca gcagctgcca tcgcttggct tttgggaagc tcaacgagcc 901 aaaaagtcat atacttggtc atgatactgc tgattgcccc ggcatacagc atcaggtgca 961 taggagtcag caatagggac tttgtggaag gtatgtcagg tgggacttgg gttgatgttg 1021 tcttggaaca tggaggttgt gtcaccgtaa tggcacagga caaaccgact gtcgacatag 1081 agctggttac aacaacagtc agcaacatgg cggaggtaag atcctactgc tatgaggcat 1141 caatatcaga catggcttcg gacagccgct gcccaacaca aggtgaagcc taccttgaca 1201 agcaatcaga cactcaatat gtctgcaaaa gaacgttagt ggacagaggc tggggaaatg 1261 gatgtggact ttttggcaaa gggagcctgg tgacatgcgc taagtttgca tgctccaaga 1321 aaatgaccgg gaagagcatc cagccagaga atctggagta ccggataatg ttgtcagttc 1381 atggctccca gcacagtggg atgatcgtta atgacacagg acatgaaact gatgagaata 1441 gagcgaaggt tgagataacg cccaattcac caagagccga agccaccctg gggggttttg 1501 gaagcctagg acttgattgt gaaccgagga caggccttga cttttcagat ttgtattact 1561 tgactatgaa taacaagcac tggttggttc acaaggagtg gttccacgac attccattac 1621 cttggcacgc tggggcagac accggaactc cacactggaa caacaaagaa gcactggtag 1681 agttcaagga cgcacatgcc aaaaggcaaa ctgtcgtggt tctagggagt caagaaggag 1741 cagttcacac ggcccttgct ggagctctgg aggctgagat ggatggtgca aagggaaggc 1801 tgtcctctgg ccacttgaaa tgtcgcctga aaatggataa acttagattg aagggcgtgt 1861 catactcctt gtgtaccgca gcgttcacat tcaccaagat cccggctgaa acactgcacg 1921 ggacagtcac agtggaggta cagtacgcag ggacagatgg accttgcaag gttccagctc 1981 agatggcggt ggacatgcaa actctgaccc cagttgggag gttgataacc gctaaccccg 2041 taatcactga aagcactgag aactctaaga tgatgctgga acttgatcca ccatttgggg 2101 actcttacat tgtcatagga gtcggggaga agaagatcac ccaccactgg cacaggagtg 2161 gcagcaccat tggaaaagca tttgaagcca ctgtgagagg tgccaagaga atggcagtct 2221 tgggagacac agcctgggac tttggatcag ttggaggcgc tctcaactca ttgggcaagg 2281 gcatccatca aatttttgga gcagctttca aatcattgtt tggaggaatg tcctggttct 2341 cacaaattct cattggaacg ttgctgatgt ggttgggtct gaacacaaag aatggatcta 2401 tttcccttat gtgcttggcc ttagggggag tgttgatctt cttatccaca gccgtctctg 2461 ctgatgtggg gtgctcggtg gacttctcaa agaaggagac gagatgtggt acaggggtgt 2521 tcgtctataa cgacgttgaa gcctggaggg acaggtacaa gtaccatcct gactcccccc 2581 gtagattggc agcagcagtc aagcaagcct gggaagatgg tatctgcggg atctcctctg 2641 tttcaagaat ggaaaacatc atgtggagat cagtagaagg ggagctcaac gcaatcctgg 2701 aagagaatgg agttcaactg acggtcgttg tgggatctgt aaaaaacccc atgtggagag 2761 gtccacagag attgcccgtg cctgtgaacg agctgcccca cggctggaag gcttggggga 2821 aatcgtactt cgtcagagca gcaaagacaa ataacagctt tgtcgtggat ggtgacacac 2881 tgaaggaatg cccactcaaa catagagcat ggaacagctt tcttgtggag gatcatgggt 2941 tcggggtatt tcacactagt gtctggctca aggttagaga agattattca ttagagtgtg 3001 atccagccgt tattggaaca gctgttaagg gaaaggaggc tgtacacagt gatctaggct 3061 actggattga gagtgagaag aatgacacat ggaggctgaa gagggcccat ctgatcgaga 3121 tgaaaacatg tgaatggcca aagtcccaca cattgtggac agatggaata gaagagagtg 3181 atctgatcat acccaagtct ttagctgggc cactcagcca tcacaatacc agagagggct 3241 ataggaccca aatgaaaggg ccatggcaca gtgaagagct tgaaattcgg tttgaggaat 3301 gcccaggcac taaggtccac gtggaggaaa catgtggaac aagaggacca tctctgagat 3361 caaccactgc aagcggaagg gtgatcgagg aatggtgctg cagggagtgc acaatgcccc 3421 cactgtcgtt ctgggctaaa gatggctgtt ggtatggaat ggagataagg cccaggaaag 3481 aaccagaaag caacttagta aggtcaatgg tgactgcagg atcaactgat cacatggatc 3541 acttctccct tggagtgctt gtgattctgc tcatggtgca ggaagggctg aagaagagaa 3601 tgaccacaaa gatcatcata agcacatcaa tggcagtgct ggtagctatg atcctgggag 3661 gattttcaat gagtgacctg gctaagcttg caattttgat gggtgccacc ttcgcggaaa 3721 tgaacactgg aggagatgta gctcatctgg cgctgatagc ggcattcaaa gtcagaccag 3781 cgttgctggt atctttcatc ttcagagcta attggacacc ccgtgaaagc atgctgctgg 3841 ccttggcctc gtgtcttttg caaactgcga tctccgcctt ggagggcgac ctgatggttc 3901 tcatcaatgg ttttgctttg gcctggttgg caatacgagc gatggttgtt ccacgcactg 3961 acaacatcac cttggcaatc ctggctgctc tgacaccact ggcccggggc acactgcttg 4021 tggcgtggag agcaggcctt gctacttgcg gggggtttat gctcctctct ctgaagggaa 4081 aaggcagtgt gaagaagaac ttaccatttg tcatggccct gggactaacc gctgtgaggc 4141 tggtcgaccc catcaacgtg gtgggactgc tgttgctcac aaggagtggg aagcggagct 4201 ggccccctag cgaagtactc acagctgttg gcctgatatg cgcattggct ggagggttcg 4261 ccaaggcaga tatagagatg gctgggccca tggccgcggt cggtctgcta attgtcagtt 4321 acgtggtctc aggaaagagt gtggacatgt acattgaaag agcaggtgac atcacatggg 4381 aaaaagatgc ggaagtcact ggaaacagtc cccggctcga tgtggcgcta gatgagagtg 4441 gtgatttctc cctggtggag gatgacggtc cccccatgag agagatcata ctcaaggtgg 4501 tcctgatgac catctgtggc atgaacccaa tagccatacc ctttgcagct ggagcgtggt 4561 acgtatacgt gaagactgga aaaaggagtg gtgctctatg ggatgtgcct gctcccaagg 4621 aagtaaaaaa gggggagacc acagatggag tgtacagagt aatgactcgt agactgctag 4681 gttcaacaca agttggagtg ggagttatgc aagagggggt ctttcacact atgtggcacg 4741 tcacaaaagg atccgcgctg agaagcggtg aagggagact tgatccatac tggggagatg 4801 tcaagcagga tctggtgtca tactgtggtc catggaagct agatgccgcc tgggacgggc 4861 acagcgaggt gcagctcttg gccgtgcccc ccggagagag agcgaggaac atccagactc 4921 tgcccggaat atttaagaca aaggatgggg acattggagc ggttgcgctg gattacccag 4981 caggaacttc aggatctcca atcctagaca agtgtgggag agtgatagga ctttatggca 5041 atggggtcgt gatcaaaaat gggagttatg ttagtgccat cacccaaggg aggagggagg 5101 aagagactcc tgttgagtgc ttcgagcctt cgatgctgaa gaagaagcag ctaactgtct 5161 tagacttgca tcctggagct gggaaaacca ggagagttct tcctgaaata gtccgtgaag 5221 ccataaaaac aagactccgt actgtgatct tagctccaac cagggttgtc gctgctgaaa 5281 tggaggaagc ccttagaggg cttccagtgc gttatatgac aacagcagtc aatgtcaccc 5341 actctggaac agaaatcgtc gacttaatgt gccatgccac cttcacttca cgtctactac 5401 agccaatcag agtccccaac tataatctgt atattatgga tgaggcccac ttcacagatc 5461 cctcaagtat agcagcaaga ggatacattt caacaagggt tgagatgggc gaggcggctg 5521 ccatcttcat gaccgccacg ccaccaggaa cccgtgacgc atttccggac tccaactcac 5581 caattatgga caccgaagtg gaagtcccag agagagcctg gagctcaggc tttgattggg 5641 tgacggatca ttctggaaaa acagtttggt ttgttccaag cgtgaggaac ggcaatgaga 5701 tcgcagcttg tctgacaaag gctggaaaac gggtcataca gctcagcaga aagacttttg 5761 agacagagtt ccagaaaaca aaacatcaag agtgggactt tgtcgtgaca actgacattt 5821 cagagatggg cgccaacttt aaagctgacc gtgtcataga ttccaggaga tgcctaaagc 5881 cggtcatact tgatggcgag agagtcattc tggctggacc catgcctgtc acacatgcca 5941 gcgctgccca gaggaggggg cgcataggca ggaatcccaa taaacctgga gatgagtatc 6001 tgtatggagg tgggtgcgca gagactgacg aagaccatgc acactggctt gaagcaagaa 6061 tgctccttga caatatttac ctccaagatg gcctcatagc ctcgctctat cgacctgagg 6121 ccgacaaagt agcagccatt gagggagagt tcaagcttag gacggagcaa aggaagacct 6181 ttgtggaact catgaaaaga ggagatcttc ctgtttggct ggcctatcag gttgcatctg 6241 ccggaataac ctacacagat agaagatggt gctttgatgg cacgaccaac aacaccataa 6301 tggaagacag tgtgccggca gaggtgtgga ccagacacgg agagaaaaga gtgctcaaac 6361 cgaggtggat ggacgccaga gtttgttcag atcatgcggc cctgaagtca ttcaaggagt 6421 ttgccgctgg gaaaagagga gcggcttttg gagtgatgga agccctggga acactgccag 6481 gacacatgac agagagattc caggaagcca ttgacaacct cgctgtgctc atgcgggcag 6541 agactggaag caggccttac aaagccgcgg cggcccaatt gccggagacc ctagagacca 6601 ttatgctttt ggggttgctg ggaacagtct cgctgggaat ctttttcgtc ttgatgagga 6661 acaagggcat agggaagatg ggctttggaa tggtgactct tggggccagc gcatggctca 6721 tgtggctctc ggaaattgag ccagccagaa ttgcatgtgt cctcattgtt gtgttcctat 6781 tgctggtggt gctcatacct gagccagaaa agcaaagatc tccccaggac aaccaaatgg 6841 caatcatcat catggtagca gtaggtcttc tgggcttgat taccgccaat gaactcggat 6901 ggttggagag aacaaagagt gacctaagcc atctaatggg aaggagagag gagggggcaa 6961 ccataggatt ctcaatggac attgacctgc ggccagcctc agcttgggcc atctatgctg 7021 ccttgacaac tttcattacc ccagccgtcc aacatgcagt gaccacttca tacaacaact 7081 actccttaat ggcgatggcc acgcaagctg gagtgttgtt tggtatgggc aaagggatgc 7141 cattctacgc atgggacttt ggagtcccgc tgctaatgat aggttgctac tcacaattaa 7201 cacccctgac cctaatagtg gccatcattt tgctcgtggc gcactacatg tacttgatcc 7261 cagggctgca ggcagcagct gcgcgtgctg cccagaagag aacggcagct ggcatcatga 7321 agaaccctgt tgtggatgga atagtggtga ctgacattga cacaatgaca attgaccccc 7381 aagtggagaa aaagatggga caggtgctac tcatagcagt agccgtctcc agcgccatac 7441 tgtcgcggac cgcctggggg tggggggagg ctggggccct gatcacagcc gcaacttcca 7501 ctttgtggga aggctctccg aacaagtact ggaactcctc tacagccact tcactgtgta 7561 acatttttag gggaagttac ttggctggag cttctctaat ctacacagta acaagaaacg 7621 ctggcttggt caagagacgt gggggtggaa caggagagac cctgggagag aaatggaagg 7681 cccgcttgaa ccagatgtcg gccctggagt tctactccta caaaaagtca ggcatcaccg 7741 aggtgtgcag agaagaggcc cgccgcgccc tcaaggacgg tgtggcaacg ggaggccatg 7801 ctgtgtcccg aggaagtgca aagctgagat ggttggtgga gcggggatac ctgcagccct 7861 atggaaaggt cattgatctt ggatgtggca gagggggctg gagttactac gccgccacca 7921 tccgcaaagt tcaagaagtg aaaggataca caaaaggagg ccctggtcat gaagaacccg 7981 tgttggtgca aagctatggg tggaacatag tccgtcttaa gagtggggtg gacgtctttc 8041 atatggcggc tgagccgtgt gacacgttgc tgtgtgacat aggtgagtca tcatctagtc 8101 ctgaagtgga agaagcacgg acgctcagag tcctctccat ggtgggggat tggcttgaaa 8161 aaagaccagg agccttttgt ataaaagtgt tgtgcccata caccagcact atgatggaaa 8221 ccctggagcg actgcagcgt aggtatgggg gaggactggt cagagtgcca ctctcccgca 8281 actctacaca tgagatgtac tgggtctctg gagcgaaaag caacaccata aaaagtgtgt 8341 ccaccacgag ccagctcctc ttggggcgca tggacgggcc taggaggcca gtgaaatatg 8401 aggaggatgt gaatctcggc tctggcacgc gggctgtggt aagctgcgct gaagctccca 8461 acatgaagat cattggtaac cgcattgaaa ggatccgcag tgagcacgcg gaaacgtggt 8521 tctttgacga gaaccaccca tataggacat gggcttacca tggaagctat gaggccccca 8581 cacaagggtc agcgtcctct ctaataaacg gggttgtcag gctcctgtca aaaccctggg 8641 atgtggtgac tggagtcaca ggaatagcca tgaccgacac cacaccgtat ggtcagcaaa 8701 gagttttcaa ggaaaaagtg gacactaggg tgccagaccc ccaagaaggc actcgtcagg 8761 ttatgagcat ggtctcttcc tggttgtgga aagagctagg caaacacaaa cggccacgag 8821 tctgtaccaa agaagagttc atcaacaagg ttcgtagcaa tgcagcatta ggggcaatat 8881 ttgaagagga aaaagagtgg aagactgcag tggaagctgt gaacgatcca aggttctggg 8941 ctctagtgga caaggaaaga gagcaccacc tgagaggaga gtgccagagt tgtgtgtaca 9001 acatgatggg aaaaagagaa aagaaacaag gggaatttgg aaaggccaag ggcagccgcg 9061 ccatctggta tatgtggcta ggggctagat ttctagagtt cgaagccctt ggattcttga 9121 acgaggatca ctggatgggg agagagaact caggaggtgg tgttgaaggg ctgggattac 9181 aaagactcgg atatgtcctt gaagagatga gtcgcatacc aggaggaagg atgtatgcag 9241 atgacactgc tggctgggac acccgcatta gcaggtttga tctggagaat gaagctctaa 9301 tcaccaacca aatggagaaa gggcacaggg ccttggcatt ggccataatc aagtacacat 9361 accaaaacaa agtggtaaag gtccttagac cagctgaaaa agggaaaaca gttatggaca 9421 ttatttcgag acaagaccaa agggggagcg gacaagttgt cacttacgct cttaacacat 9481 ttaccaacct agtggtgcaa ctcattcgga atatggaggc tgaggaagtt ctggagatgc 9541 aagacttgtg gctgctgcgg aggtcagaga aagtgaccaa ctggttgcag agcaacggat 9601 gggataggct caaacgaatg gcagtcagtg gagatgattg cgttgtgaag ccaattgatg 9661 ataggtttgc acatgccctc aggttcttga atgatatggg aaaagttagg aaggacacac 9721 aagagtggaa accctcaact ggatgggaca actgggaaga agttccgttt tgctcccacc 9781 acttcaacaa gctccatctc aaggacggga ggtccattgt ggttccctgc cgccaccaag 9841 atgaactgat tggccgggcc cgcgtctctc caggggcggg atggagcatc cgggagactg 9901 cttgcctagc aaaatcatat gcgcaaatgt ggcagctcct ttatttccac agaagggacc 9961 tccgactgat ggccaatgcc atttgttcat ctgtgccagt tgactgggtt ccaactggga 10021 gaactacctg gtcaatccat ggaaagggag aatggatgac cactgaagac atgcttgtgg 10081 tgtggaacag agtgtggatt gaggagaacg accacatgga agacaagacc ccagttgcga 10141 aatggacaga cattccctat ttgggaaaaa gggaagactt gtggtgtgga tctctcatag 10201 ggcacagacc gcgcaccacc tgggctgaga acattaaaaa cacagtcaac atggtgcgca 10261 ggatcatagg tgatgaagaa aagtacatgg actacctatc cacccaagtt cgctacttgg 10321 gtgaagaagg gtctacacct ggagtgctgt aagcaccaat cttaatgttg tcaggcctgc 10381 tagtcag

Sequences producing significant alignments: Select:AllNone Selected:0 AlignmentsDownloadGenBankGraphicsDistance tree of resultsShow/hide columns of the table presenting sequences producing significant alignments Sequences producing significant alignments: Select for downloading or viewing reports Description Max score Total score Query cover E value Ident Accession Select seq gb|KY317940.1| Zika virus isolate ZIKV/Homo_sapiens/Colombia/2016/ZC207Se polyprotein gene, complete cds 18969 18969 100% 0.0 100% KY317940.1 Select seq gb|KY317938.1| Zika virus isolate ZIKV/Homo_sapiens/Colombia/2016/ZC199Se polyprotein gene, complete cds 18914 18914 100% 0.0 99% KY317938.1 Select seq gb|KY317939.1| Zika virus isolate ZIKV/Homo_sapiens/Colombia/2016/ZC204Se polyprotein gene, complete cds 18894 18894 100% 0.0 99% KY317939.1 Select seq gb|KX198135.2| Zika virus strain ZIKV/Homo sapiens/PAN/BEI-259634_V4/2016, complete genome 18892 18892 100% 0.0 99% KX198135.2 Select seq gb|KY317936.1| Zika virus isolate ZIKV/Homo_sapiens/Colombia/2016/ZC188Se polyprotein gene, complete cds 18886 18886 100% 0.0 99% KY317936.1 Select seq gb|KY014303.1| Zika virus isolate Zika virus/H.sapiens-wt/DOM/2016/BB-0127-SER polyprotein gene, complete cds 18886 18886 100% 0.0 99% KY014303.1 Select seq gb|KX156776.2| Zika virus strain ZIKV/Homo sapiens/PAN/CDC-259364_V1-V2/2015, complete genome 18881 18881 100% 0.0 99% KX156776.2 Select seq gb|KX156774.2| Zika virus strain ZIKV/Homo sapiens/PAN/CDC-259359_V1-V3/2015, complete genome 18875 18875 100% 0.0 99% KX156774.2 Select seq gb|KX156775.2| Zika virus strain ZIKV/Homo sapiens/PAN/CDC-259249_V1-V3/2015, complete genome 18870 18870 100% 0.0 99% KX156775.2 Select seq gb|KX087102.2| Zika virus strain ZIKV/Homo sapiens/COL/FLR/2015, complete genome 18870 18870 100% 0.0 99% KX087102.2 Select seq gb|KU820897.5| Zika virus isolate FLR polyprotein gene, complete cds 18870 18870 100% 0.0 99% KU820897.5 Select seq gb|KX247646.1| Zika virus isolate Zika virus/Homo sapiens/COL/UF-1/2016, complete genome 18870 18870 100% 0.0 99% KX247646.1 Select seq gb|KU647676.1| Zika virus strain MRS_OPY_Martinique_PaRi_2015 polyprotein gene, complete cds 18864 18864 100% 0.0 99% KU647676.1 Select seq gb|KY317937.1| Zika virus isolate ZIKV/Homo_sapiens/Colombia/2016/ZC192Se polyprotein gene, complete cds 18848 18848 100% 0.0 99% KY317937.1 Select seq gb|KU922960.1| Zika virus isolate MEX/InDRE/Sm/2016, complete genome 18842 18842 100% 0.0 99% KU922960.1 Select seq gb|KX893855.1| Zika virus strain Zika virus/Homo sapiens/VEN/UF-2/2016, complete genome 18840 18840 100% 0.0 99% KX893855.1 Select seq gb|KX702400.1| Zika virus strain Zika virus/Homo sapiens/VEN/UF-1/2016, complete genome 18836 18836 100% 0.0 99% KX702400.1 Select seq gb|KX548902.1| Zika virus isolate ZIKV/COL/FCC00093/2015 polyprotein gene, complete cds 18836 18836 100% 0.0 99% KX548902.1 Select seq gb|KU922923.1| Zika virus isolate MEX/InDRE/Lm/2016, complete genome 18836 18836 100% 0.0 99% KU922923.1 Select seq gb|KX447510.1| Zika virus isolate 1_0049_PF polyprotein gene, complete cds 18814 18814 100% 0.0 99% KX447510.1 Select seq gb|KU991811.1| Zika virus isolate Brazil/2016/INMI1 polyprotein gene, complete cds 18809 18809 100% 0.0 99% KU991811.1 Select seq gb|KY075932.1| Zika virus isolate ZIKV/Homo_sapiens/USA/2016/FL001Sa polyprotein gene, complete cds 18803 18803 100% 0.0 99% KY075932.1 Select seq gb|KX447512.1| Zika virus isolate 1_0181_PF polyprotein gene, complete cds 18803 18803 100% 0.0 99% KX447512.1 Select seq gb|KX369547.1| Zika virus strain PF13/251013-18, complete genome 18803 18803 100% 0.0 99% KX369547.1 Select seq gb|KX280026.1| Zika virus isolate Paraiba_01, complete genome 18803 18803 100% 0.0 99% KX280026.1 Select seq gb|KU509998.3| Zika virus strain Haiti/1225/2014, complete genome 18803 18803 100% 0.0 99% KU509998.3 Select seq gb|KJ776791.2| Zika virus strain H/PF/2013, complete genome 18798 18798 100% 0.0 99% KJ776791.2 Select seq gb|KX447509.1| Zika virus isolate 1_0087_PF polyprotein gene, complete cds 18798 18798 100% 0.0 99% KX447509.1 Select seq gb|KX447513.1| Zika virus isolate 1_0134_PF polyprotein gene, complete cds 18792 18792 100% 0.0 99% KX447513.1 Select seq gb|KR872956.1| Zika virus strain 17829 polyprotein gene, complete cds 18787 18787 100% 0.0 99% KR872956.1 Select seq gb|KX197205.1| Zika virus isolate 9, complete genome 18787 18787 100% 0.0 99% KX197205.1 Select seq gb|KX447515.1| Zika virus isolate 1_0030_PF polyprotein gene, complete cds 18787 18787 100% 0.0 99% KX447515.1 Select seq gb|KX447511.1| Zika virus isolate 1_0015_PF polyprotein gene, complete cds 18787 18787 100% 0.0 99% KX447511.1 Select seq gb|KU707826.1| Zika virus isolate SSABR1, complete genome 18787 18787 100% 0.0 99% KU707826.1 Select seq gb|KU365779.1| Zika virus strain BeH819966 polyprotein gene, complete cds 18787 18787 100% 0.0 99% KU365779.1 Select seq gb|KU321639.1| Zika virus strain ZikaSPH2015, complete genome 18787 18787 100% 0.0 99% KU321639.1 Select seq gb|KX811222.1| Zika virus isolate Brazil_2015_MG, complete genome 18781 18781 100% 0.0 99% KX811222.1 Select seq gb|KX447514.1| Zika virus isolate 1_0035_PF polyprotein gene, complete cds 18781 18781 100% 0.0 99% KX447514.1 Select seq gb|KX262887.1| Zika virus isolate 103451, complete genome 18781 18781 100% 0.0 99% KX262887.1 Select seq gb|KX051563.1| Zika virus isolate Haiti/1/2016, complete genome 18781 18781 100% 0.0 99% KX051563.1 Select seq gb|KX447516.1| Zika virus isolate 1_0111_PF polyprotein gene, complete cds 18776 18776 100% 0.0 99% KX447516.1 Select seq gb|KU729218.1| Zika virus isolate BeH828305 polyprotein gene, complete cds 18776 18776 100% 0.0 99% KU729218.1 Select seq gb|KX694534.2| Zika virus strain ZIKV/Homo sapiens/HND/R103451/2015, complete genome 18770 18770 100% 0.0 99% KX694534.2 Select seq gb|KU758877.1| Zika virus isolate 17271 polyprotein gene, complete cds 18770 18770 100% 0.0 99% KU758877.1 Select seq gb|KX197192.1| Zika virus isolate ZIKV/H.sapiens/Brazil/PE243/2015, complete genome 18770 18770 100% 0.0 99% KX197192.1 Select seq gb|KU926309.1| Zika virus isolate Rio-U1, complete genome 18770 18770 100% 0.0 99% KU926309.1 Select seq gb|KU365780.1| Zika virus strain BeH815744 polyprotein gene, complete cds 18770 18770 100% 0.0 99% KU365780.1 Select seq gb|KY014297.1| Zika virus isolate Zika virus/H.sapiens-wt/BRA/2016/FC-6864-URI polyprotein gene, complete cds 18768 18768 100% 0.0 99% KY014297.1 Select seq gb|KU497555.1| Zika virus isolate Brazil-ZKV2015, complete genome 18766 18766 99% 0.0 99% KU497555.1 Select seq gb|KU365777.1| Zika virus strain BeH818995 polyprotein gene, complete cds 18764 18764 100% 0.0 99% KU365777.1 Select seq gb|KY328289.1| Zika virus isolate HN16, complete genome 18759 18759 100% 0.0 99% KY328289.1 Select seq gb|KX879604.1| Zika virus isolate SN089, complete genome 18759 18759 100% 0.0 99% KX879604.1 Select seq gb|KU940228.1| Zika virus isolate Bahia07, partial genome 18759 18759 100% 0.0 99% KU940228.1 Select seq gb|KU501217.1| Zika virus strain 8375 polyprotein gene, complete cds 18759 18759 100% 0.0 99% KU501217.1 Select seq gb|KU365778.1| Zika virus strain BeH819015 polyprotein gene, complete cds 18759 18759 100% 0.0 99% KU365778.1 Select seq gb|KU312312.1| Zika virus isolate Z1106033 polyprotein gene, complete cds 18759 18759 100% 0.0 99% KU312312.1 Select seq gb|KU527068.1| Zika virus strain Natal RGN, complete genome 18753 18753 100% 0.0 99% KU527068.1 Select seq gb|KU501216.1| Zika virus strain 103344 polyprotein gene, complete cds 18753 18753 100% 0.0 99% KU501216.1 Select seq gb|KY014327.1| Zika virus isolate Zika virus/H.sapiens-wt/HND/2016/HU-ME167-PLA polyprotein gene, complete cds 18750 18750 100% 0.0 99% KY014327.1 Select seq gb|KY120348.1| Zika virus isolate CIENI551, complete genome 18748 18748 100% 0.0 99% KY120348.1 Select seq gb|KX879603.1| Zika virus isolate SN062, complete genome 18748 18748 100% 0.0 99% KX879603.1 Select seq gb|KX247632.1| Zika virus isolate MEX_I_7 polyprotein gene, complete cds 18748 18748 100% 0.0 99% KX247632.1 Select seq gb|KU937936.1| Zika virus isolate ZIKVNL00013 polyprotein gene, complete cds 18748 18748 100% 0.0 99% KU937936.1 Select seq gb|KU501215.1| Zika virus strain PRVABC59, complete genome 18748 18748 100% 0.0 99% KU501215.1 Select seq gb|KX087101.3| Zika virus strain ZIKV/Homo sapiens/PRI/PRVABC59/2015, complete genome 18742 18742 100% 0.0 99% KX087101.3 Select seq gb|KY014315.1| Zika virus isolate Zika virus/H.sapiens-wt/HND/2016/HU-ME152-SER polyprotein gene, complete cds 18742 18742 100% 0.0 99% KY014315.1 Select seq gb|KX601168.1| Zika virus strain ZIKV/Homo Sapiens/PRI/PRVABC59/2015, complete genome 18742 18742 100% 0.0 99% KX601168.1 Select seq gb|KU729217.2| Zika virus isolate BeH823339 polyprotein gene, complete cds 18742 18742 100% 0.0 99% KU729217.2 Select seq gb|KX446951.2| Zika virus strain ZIKV/Aedes.sp/MEX/MEX_I-7/2016, complete genome 18737 18737 100% 0.0 99% KX446951.2 Select seq gb|KX446950.2| Zika virus strain ZIKV/Aedes.sp/MEX/MEX_2-81/2016, complete genome 18737 18737 100% 0.0 99% KX446950.2 Select seq gb|KX856011.1| Zika virus strain ZIKV/Aedes sp./MEX_I-44/2016, complete genome 18737 18737 100% 0.0 99% KX856011.1 Select seq gb|KX447517.1| Zika virus isolate 1_0038_PF polyprotein gene, complete cds 18737 18737 100% 0.0 99% KX447517.1 Select seq gb|KX520666.1| Zika virus isolate HS-2015-BA-01 polyprotein gene, complete cds 18737 18737 100% 0.0 99% KX520666.1 Select seq gb|KX377337.1| Zika virus strain PRVABC-59, complete genome 18737 18737 100% 0.0 99% KX377337.1 Select seq gb|KU820898.1| Zika virus isolate GZ01 polyprotein gene, complete cds 18737 18737 100% 0.0 99% KU820898.1 Select seq gb|KX269878.1| Zika virus isolate Haiti/2016/PD, complete genome 18733 18733 100% 0.0 99% KX269878.1 Select seq gb|KY075939.1| Zika virus isolate ZIKV/Aedes_aegypti/USA/2016/FL08M polyprotein gene, complete cds 18731 18731 100% 0.0 99% KY075939.1 Select seq gb|KY075933.1| Zika virus isolate ZIKV/Homo_sapiens/USA/2016/FL008U polyprotein gene, complete cds 18731 18731 100% 0.0 99% KY075933.1 Select seq gb|KY014304.1| Zika virus isolate Zika virus/H.sapiens-wt/DOM/2016/BB-0180-SER polyprotein gene, complete cds 18731 18731 100% 0.0 99% KY014304.1 Select seq gb|KU870645.1| Zika virus isolate FB-GWUH-2016, complete genome 18731 18731 100% 0.0 99% KU870645.1 Select seq gb|KY014296.1| Zika virus isolate Zika virus/H.sapiens-wt/BRA/2016/FC-DQ131D1-URI polyprotein gene, complete cds 18726 18726 100% 0.0 99% KY014296.1 Select seq gb|KX806557.2| Zika virus isolate TS17-2016, complete genome 18726 18726 100% 0.0 99% KX806557.2 Select seq gb|KU926310.1| Zika virus isolate Rio-S1, complete genome 18726 18726 100% 0.0 99% KU926310.1 Select seq gb|KU853013.1| Zika virus isolate Dominican Republic/2016/PD2, complete genome 18726 18726 100% 0.0 99% KU853013.1 Select seq gb|KU853012.1| Zika virus isolate Dominican Republic/2016/PD1, complete genome 18724 18724 100% 0.0 99% KU853012.1 Select seq gb|KY075934.1| Zika virus isolate ZIKV/Homo_sapiens/USA/2016/FL016U polyprotein gene, complete cds 18720 18720 100% 0.0 99% KY075934.1 Select seq gb|KX056898.1| Zika virus isolate Zika virus/GZ02/2016 polyprotein gene, complete cds 18720 18720 100% 0.0 99% KX056898.1 Select seq gb|KU955590.1| Zika virus isolate Z16019 polyprotein gene, complete cds 18720 18720 100% 0.0 99% KU955590.1 Select seq gb|KX766028.1| Zika virus isolate R114916, complete genome 18716 18716 100% 0.0 99% KX766028.1 Select seq gb|KY003153.1| Zika virus strain ZIKV/34997/Pavia/2016 polyprotein gene, complete cds 18715 18715 100% 0.0 99% KY003153.1 Select seq gb|KU740184.2| Zika virus isolate GD01 polyprotein gene, complete cds 18715 18715 100% 0.0 99% KU740184.2 Select seq gb|KU761564.1| Zika virus isolate GDZ16001 polyprotein gene, complete cds 18715 18715 100% 0.0 99% KU761564.1 Select seq gb|KY014300.1| Zika virus isolate Zika virus/H.sapiens-wt/DOM/2016/BB-0208-SER polyprotein gene, complete cds 18709 18709 100% 0.0 99% KY014300.1 Select seq dbj|LC190723.1| Zika virus genomic RNA, complete genome, strain: ZIKV/Hu/Yokohama/1/2016 18709 18709 100% 0.0 99% LC190723.1 Select seq gb|KY120349.1| Zika virus isolate CIENI551, complete genome 18705 18705 100% 0.0 99% KY120349.1 Select seq gb|KY014321.1| Zika virus isolate Zika virus/H.sapiens-wt/DOM/2016/BB-0115-SER polyprotein gene, complete cds 18703 18703 100% 0.0 99% KY014321.1 Select seq gb|KX766029.1| Zika virus isolate R116265, complete genome 18703 18703 100% 0.0 99% KX766029.1 Select seq gb|KY014295.1| Zika virus isolate Zika virus/H.sapiens-wt/USA/2016/FL-010-URI polyprotein gene, complete cds 18698 18698 100% 0.0 99% KY014295.1 Select seq gb|KX842449.2| Zika virus isolate ZIKV/Homo_sapiens/USA/2016/FL010U polyprotein gene, complete cds 18698 18698 100% 0.0 99% KX842449.2 Select seq gb|KY003154.1| Zika virus strain ZIKV/VR10599/Pavia/2016 polyprotein gene, complete cds 18692 18692 100% 0.0 99% KY003154.1

LOCUS KY317940 10391 bp RNA linear VRL 27-DEC-2016 DEFINITION Zika virus isolate ZIKV/Homo_sapiens/Colombia/2016/ZC207Se polyprotein gene, complete cds. ACCESSION KY317940 VERSION KY317940.1 KEYWORDS . SOURCE Zika virus ORGANISM Zika virus Viruses; ssRNA viruses; ssRNA positive-strand viruses, no DNA stage; Flaviviridae; Flavivirus. REFERENCE 1 (bases 1 to 10391) AUTHORS Grubaugh,N., Rogers,T., Beutler,N., Fredeking,T., Gangavarupu,K., Oliveira,G., Robles-Sikisaka,R., Burton,D. and Andersen,K. TITLE Zika virus sequenced from Colombia, 2016 JOURNAL Unpublished REFERENCE 2 (bases 1 to 10391) AUTHORS Grubaugh,N., Rogers,T., Beutler,N., Fredeking,T., Gangavarupu,K., Oliveira,G., Robles-Sikisaka,R., Burton,D. and Andersen,K. TITLE Direct Submission JOURNAL Submitted (09-DEC-2016) Department of Immunology and Microbial Science, The Scripps Research Institute, 10550 North Torrey Pines Road, IMM-210, La Jolla, CA 92037, USA COMMENT ##Assembly-Data-START## Assembly Method :: NovoAlign v. V3.04 Sequencing Technology :: Illumina ##Assembly-Data-END## FEATURES Location/Qualifiers source 1..10391 /organism="Zika virus" /mol_type="genomic RNA" /isolate="ZIKV/Homo_sapiens/Colombia/2016/ZC207Se" /isolation_source="serum" /host="Homo sapiens" /db_xref="taxon:64320" /country="Colombia" /collection_date="09-Jan-2016" /collected_by="Antibody Systems Inc" CDS 82..10353 /codon_start=1 /product="polyprotein" /protein_id="APQ41786.1" /translation="MKNPKKKSGGFRIVNMLKRGVARVSPFGGLKRLPAGLLLGHGPI RMVLAILAFLRFTAIKPSLGLINRWGSVGKKEAMEIIKKFKKDLAAMLRIINARKEKK RRGAETSVGIVGLLLTTAMAAEVTRRGSAYYMYLDRNDAGEAISFPTTLGMNKCYIQI MDLGHMCDATMSYECPMLDEGVEPDDVDCWCNTTSTWVVYGTCHHKKGEARRSRRAVT LPSHSTRKLQTRSQTWLESREYTKHLIRVENWIFRNPGFALAAAAIAWLLGSSTSQKV IYLVMILLIAPAYSIRCIGVSNRDFVEGMSGGTWVDVVLEHGGCVTVMAQDKPTVDIE LVTTTVSNMAEVRSYCYEASISDMASDSRCPTQGEAYLDKQSDTQYVCKRTLVDRGWG NGCGLFGKGSLVTCAKFACSKKMTGKSIQPENLEYRIMLSVHGSQHSGMIVNDTGHET DENRAKVEITPNSPRAEATLGGFGSLGLDCEPRTGLDFSDLYYLTMNNKHWLVHKEWF HDIPLPWHAGADTGTPHWNNKEALVEFKDAHAKRQTVVVLGSQEGAVHTALAGALEAE MDGAKGRLSSGHLKCRLKMDKLRLKGVSYSLCTAAFTFTKIPAETLHGTVTVEVQYAG TDGPCKVPAQMAVDMQTLTPVGRLITANPVITESTENSKMMLELDPPFGDSYIVIGVG EKKITHHWHRSGSTIGKAFEATVRGAKRMAVLGDTAWDFGSVGGALNSLGKGIHQIFG AAFKSLFGGMSWFSQILIGTLLMWLGLNTKNGSISLMCLALGGVLIFLSTAVSADVGC SVDFSKKETRCGTGVFVYNDVEAWRDRYKYHPDSPRRLAAAVKQAWEDGICGISSVSR MENIMWRSVEGELNAILEENGVQLTVVVGSVKNPMWRGPQRLPVPVNELPHGWKAWGK SYFVRAAKTNNSFVVDGDTLKECPLKHRAWNSFLVEDHGFGVFHTSVWLKVREDYSLE CDPAVIGTAVKGKEAVHSDLGYWIESEKNDTWRLKRAHLIEMKTCEWPKSHTLWTDGI EESDLIIPKSLAGPLSHHNTREGYRTQMKGPWHSEELEIRFEECPGTKVHVEETCGTR GPSLRSTTASGRVIEEWCCRECTMPPLSFWAKDGCWYGMEIRPRKEPESNLVRSMVTA GSTDHMDHFSLGVLVILLMVQEGLKKRMTTKIIISTSMAVLVAMILGGFSMSDLAKLA ILMGATFAEMNTGGDVAHLALIAAFKVRPALLVSFIFRANWTPRESMLLALASCLLQT AISALEGDLMVLINGFALAWLAIRAMVVPRTDNITLAILAALTPLARGTLLVAWRAGL ATCGGFMLLSLKGKGSVKKNLPFVMALGLTAVRLVDPINVVGLLLLTRSGKRSWPPSE VLTAVGLICALAGGFAKADIEMAGPMAAVGLLIVSYVVSGKSVDMYIERAGDITWEKD AEVTGNSPRLDVALDESGDFSLVEDDGPPMREIILKVVLMTICGMNPIAIPFAAGAWY VYVKTGKRSGALWDVPAPKEVKKGETTDGVYRVMTRRLLGSTQVGVGVMQEGVFHTMW HVTKGSALRSGEGRLDPYWGDVKQDLVSYCGPWKLDAAWDGHSEVQLLAVPPGERARN IQTLPGIFKTKDGDIGAVALDYPAGTSGSPILDKCGRVIGLYGNGVVIKNGSYVSAIT QGRREEETPVECFEPSMLKKKQLTVLDLHPGAGKTRRVLPEIVREAIKTRLRTVILAP TRVVAAEMEEALRGLPVRYMTTAVNVTHSGTEIVDLMCHATFTSRLLQPIRVPNYNLY IMDEAHFTDPSSIAARGYISTRVEMGEAAAIFMTATPPGTRDAFPDSNSPIMDTEVEV PERAWSSGFDWVTDHSGKTVWFVPSVRNGNEIAACLTKAGKRVIQLSRKTFETEFQKT KHQEWDFVVTTDISEMGANFKADRVIDSRRCLKPVILDGERVILAGPMPVTHASAAQR RGRIGRNPNKPGDEYLYGGGCAETDEDHAHWLEARMLLDNIYLQDGLIASLYRPEADK VAAIEGEFKLRTEQRKTFVELMKRGDLPVWLAYQVASAGITYTDRRWCFDGTTNNTIM EDSVPAEVWTRHGEKRVLKPRWMDARVCSDHAALKSFKEFAAGKRGAAFGVMEALGTL PGHMTERFQEAIDNLAVLMRAETGSRPYKAAAAQLPETLETIMLLGLLGTVSLGIFFV LMRNKGIGKMGFGMVTLGASAWLMWLSEIEPARIACVLIVVFLLLVVLIPEPEKQRSP QDNQMAIIIMVAVGLLGLITANELGWLERTKSDLSHLMGRREEGATIGFSMDIDLRPA SAWAIYAALTTFITPAVQHAVTTSYNNYSLMAMATQAGVLFGMGKGMPFYAWDFGVPL LMIGCYSQLTPLTLIVAIILLVAHYMYLIPGLQAAAARAAQKRTAAGIMKNPVVDGIV VTDIDTMTIDPQVEKKMGQVLLIAVAVSSAILSRTAWGWGEAGALITAATSTLWEGSP NKYWNSSTATSLCNIFRGSYLAGASLIYTVTRNAGLVKRRGGGTGETLGEKWKARLNQ MSALEFYSYKKSGITEVCREEARRALKDGVATGGHAVSRGSAKLRWLVERGYLQPYGK VIDLGCGRGGWSYYAATIRKVQEVKGYTKGGPGHEEPVLVQSYGWNIVRLKSGVDVFH MAAEPCDTLLCDIGESSSSPEVEEARTLRVLSMVGDWLEKRPGAFCIKVLCPYTSTMM ETLERLQRRYGGGLVRVPLSRNSTHEMYWVSGAKSNTIKSVSTTSQLLLGRMDGPRRP VKYEEDVNLGSGTRAVVSCAEAPNMKIIGNRIERIRSEHAETWFFDENHPYRTWAYHG SYEAPTQGSASSLINGVVRLLSKPWDVVTGVTGIAMTDTTPYGQQRVFKEKVDTRVPD PQEGTRQVMSMVSSWLWKELGKHKRPRVCTKEEFINKVRSNAALGAIFEEEKEWKTAV EAVNDPRFWALVDKEREHHLRGECQSCVYNMMGKREKKQGEFGKAKGSRAIWYMWLGA RFLEFEALGFLNEDHWMGRENSGGGVEGLGLQRLGYVLEEMSRIPGGRMYADDTAGWD TRISRFDLENEALITNQMEKGHRALALAIIKYTYQNKVVKVLRPAEKGKTVMDIISRQ DQRGSGQVVTYALNTFTNLVVQLIRNMEAEEVLEMQDLWLLRRSEKVTNWLQSNGWDR LKRMAVSGDDCVVKPIDDRFAHALRFLNDMGKVRKDTQEWKPSTGWDNWEEVPFCSHH FNKLHLKDGRSIVVPCRHQDELIGRARVSPGAGWSIRETACLAKSYAQMWQLLYFHRR DLRLMANAICSSVPVDWVPTGRTTWSIHGKGEWMTTEDMLVVWNRVWIEENDHMEDKT PVAKWTDIPYLGKREDLWCGSLIGHRPRTTWAENIKNTVNMVRRIIGDEEKYMDYLST QVRYLGEEGSTPGVL" ORIGIN 1 gcgacagttc gagtttgaag cgaaagctag caacagtatc aacaggtttt attttggatt 61 tggaaacgag agtttctggt catgaaaaac ccaaaaaaga aatccggagg attccggatt 121 gtcaatatgc taaaacgcgg agtagcccgt gtgagcccct ttgggggctt gaagaggctg 181 ccagccggac ttctgctggg tcatgggccc atcaggatgg tcttggcgat tctagccttt 241 ttgagattca cggcaatcaa gccatcactg ggtctcatca atagatgggg ttcagtgggg 301 aaaaaagagg ctatggaaat aataaagaag ttcaagaaag atctggctgc catgctgaga 361 ataatcaatg ctaggaagga gaagaagaga cgaggcgcag aaactagtgt cggaattgtt 421 ggcctcctgc tgaccacagc tatggcagcg gaggtcacta gacgtgggag tgcatactat 481 atgtacttgg acagaaacga tgctggggag gccatatctt ttccaaccac attggggatg 541 aataagtgtt atatacagat catggatctt ggacacatgt gtgatgccac catgagctat 601 gaatgcccta tgctggatga gggggtggaa ccagatgacg tcgattgttg gtgcaacacg 661 acgtcaactt gggttgtgta cggaacctgc catcacaaaa aaggtgaagc acggagatct 721 agaagagccg tgacgctccc ctcccattcc actaggaagc tgcaaacgcg gtcgcaaacc 781 tggttggaat caagagaata cacaaagcac ttgattagag tcgaaaattg gatattcagg 841 aaccctggtt tcgctttagc agcagctgcc atcgcttggc ttttgggaag ctcaaccagc 901 caaaaagtca tatacttggt catgatactg ctgattgccc cggcatacag catcaggtgc 961 ataggagtca gcaataggga ctttgtggaa ggtatgtcag gtgggacttg ggttgatgtt 1021 gtcttggaac atggaggttg tgtcaccgta atggcacagg acaaaccgac tgtcgacata 1081 gagctggtta caacaacagt cagcaacatg gcggaggtaa gatcctactg ctatgaggca 1141 tcaatatcag acatggcttc ggacagccgc tgcccaacac aaggtgaagc ctaccttgac 1201 aagcaatcag acactcaata tgtctgcaaa agaacgttag tggacagagg ctggggaaat 1261 ggatgtggac tttttggcaa agggagcctg gtgacatgcg ctaagtttgc atgctccaag 1321 aaaatgaccg ggaagagcat ccagccagag aatctggagt accggataat gttgtcagtt 1381 catggctccc agcacagtgg gatgatcgtt aatgacacag gacatgaaac tgatgagaat 1441 agagcgaagg ttgagataac gcccaattca ccaagagccg aagccaccct ggggggtttt 1501 ggaagcctag gacttgattg tgaaccgagg acaggccttg acttttcaga tttgtattac 1561 ttgactatga ataacaagca ctggttggtt cacaaggagt ggttccacga cattccatta 1621 ccttggcacg ctggggcaga caccggaact ccacactgga acaacaaaga agcactggta 1681 gagttcaagg acgcacatgc caaaaggcaa actgtcgtgg ttctagggag tcaagaagga 1741 gcagttcaca cggcccttgc tggagctctg gaggctgaga tggatggtgc aaagggaagg 1801 ctgtcctctg gccacttgaa atgtcgcctg aaaatggata aacttagatt gaagggcgtg 1861 tcatactcct tgtgtaccgc agcgttcaca ttcaccaaga tcccggctga aacactgcac 1921 gggacagtca cagtggaggt acagtacgca gggacagatg gaccttgcaa ggttccagct 1981 cagatggcgg tggacatgca aactctgacc ccagttggga ggttgataac cgctaacccc 2041 gtaatcactg aaagcactga gaactctaag atgatgctgg aacttgatcc accatttggg 2101 gactcttaca ttgtcatagg agtcggggag aagaagatca cccaccactg gcacaggagt 2161 ggcagcacca ttggaaaagc atttgaagcc actgtgagag gtgccaagag aatggcagtc 2221 ttgggagaca cagcctggga ctttggatca gttggaggcg ctctcaactc attgggcaag 2281 ggcatccatc aaatttttgg agcagctttc aaatcattgt ttggaggaat gtcctggttc 2341 tcacaaattc tcattggaac gttgctgatg tggttgggtc tgaacacaaa gaatggatct 2401 atttccctta tgtgcttggc cttaggggga gtgttgatct tcttatccac agccgtctct 2461 gctgatgtgg ggtgctcggt ggacttctca aagaaggaga cgagatgtgg tacaggggtg 2521 ttcgtctata acgacgttga agcctggagg gacaggtaca agtaccatcc tgactccccc 2581 cgtagattgg cagcagcagt caagcaagcc tgggaagatg gtatctgcgg gatctcctct 2641 gtttcaagaa tggaaaacat catgtggaga tcagtagaag gggagctcaa cgcaatcctg 2701 gaagagaatg gagttcaact gacggtcgtt gtgggatctg taaaaaaccc catgtggaga 2761 ggtccacaga gattgcccgt gcctgtgaac gagctgcccc acggctggaa ggcttggggg 2821 aaatcgtact tcgtcagagc agcaaagaca aataacagct ttgtcgtgga tggtgacaca 2881 ctgaaggaat gcccactcaa acatagagca tggaacagct ttcttgtgga ggatcatggg 2941 ttcggggtat ttcacactag tgtctggctc aaggttagag aagattattc attagagtgt 3001 gatccagccg ttattggaac agctgttaag ggaaaggagg ctgtacacag tgatctaggc 3061 tactggattg agagtgagaa gaatgacaca tggaggctga agagggccca tctgatcgag 3121 atgaaaacat gtgaatggcc aaagtcccac acattgtgga cagatggaat agaagagagt 3181 gatctgatca tacccaagtc tttagctggg ccactcagcc atcacaatac cagagagggc 3241 tacaggaccc aaatgaaagg gccatggcac agtgaagagc ttgaaattcg gtttgaggaa 3301 tgcccaggca ctaaggtcca cgtggaggaa acatgtggaa caagaggacc atctctgaga 3361 tcaaccactg caagcggaag ggtgatcgag gaatggtgct gcagggagtg cacaatgccc 3421 ccactgtcgt tctgggctaa agatggctgt tggtatggaa tggagataag gcccaggaaa 3481 gaaccagaaa gcaacttagt aaggtcaatg gtgactgcag gatcaactga tcacatggat 3541 cacttctccc ttggagtgct tgtgattctg ctcatggtgc aggaagggct gaagaagaga 3601 atgaccacaa agatcatcat aagcacatca atggcagtgc tggtagctat gatcctggga 3661 ggattttcaa tgagtgacct ggctaagctt gcaattttga tgggtgccac cttcgcggaa 3721 atgaacactg gaggagatgt agctcatctg gcgctgatag cggcattcaa agtcagacca 3781 gcgttgctgg tatctttcat cttcagagct aattggacac cccgtgaaag catgctgctg 3841 gccttggcct cgtgtctttt gcaaactgcg atctccgcct tggagggcga cctgatggtt 3901 ctcatcaatg gttttgcttt ggcctggttg gcaatacgag cgatggttgt tccacgcact 3961 gacaacatca ccttggcaat cctggctgct ctgacaccac tggcccgggg cacactgctt 4021 gtggcgtgga gagcaggcct tgctacttgc ggggggttta tgctcctctc tctgaaggga 4081 aaaggcagtg tgaagaagaa cttaccattt gtcatggccc tgggactaac cgctgtgagg 4141 ctggtcgacc ccatcaacgt ggtgggactg ctgttgctca caaggagtgg gaagcggagc 4201 tggcccccta gcgaagtact cacagctgtt ggcctgatat gcgcattggc tggagggttc 4261 gccaaggcag atatagagat ggctgggccc atggccgcgg tcggtctgct aattgtcagt 4321 tacgtggtct caggaaagag tgtggacatg tacattgaaa gagcaggtga catcacatgg 4381 gaaaaagatg cggaagtcac tggaaacagt ccccggctcg atgtggcgct agatgagagt 4441 ggtgatttct ccctggtgga ggatgacggt ccccccatga gagagatcat actcaaggtg 4501 gtcctgatga ccatctgtgg catgaaccca atagccatac cctttgcagc tggagcgtgg 4561 tacgtatacg tgaagactgg aaaaaggagt ggtgctctat gggatgtgcc tgctcccaag 4621 gaagtaaaaa agggggagac cacagatgga gtgtacagag taatgactcg tagactgcta 4681 ggttcaacac aagttggagt gggagttatg caagaggggg tctttcacac tatgtggcac 4741 gtcacaaaag gatccgcgct gagaagcggt gaagggagac ttgatccata ctggggagat 4801 gtcaagcagg atctggtgtc atactgtggt ccatggaagc tagatgccgc ctgggacggg 4861 cacagcgagg tgcagctctt ggccgtgccc cccggagaga gagcgaggaa catccagact 4921 ctgcccggaa tatttaagac aaaggatggg gacattggag cggttgcgct ggattaccca 4981 gcaggaactt caggatctcc aatcctagac aagtgtggga gagtgatagg actttatggc 5041 aatggggtcg tgatcaaaaa tgggagttat gttagtgcca tcacccaagg gaggagggag 5101 gaagagactc ctgttgagtg cttcgagcct tcgatgctga agaagaagca gctaactgtc 5161 ttagacttgc atcctggagc tgggaaaacc aggagagttc ttcctgaaat agtccgtgaa 5221 gccataaaaa caagactccg tactgtgatc ttagctccaa ccagggttgt cgctgctgaa 5281 atggaggagg cccttagagg gcttccagtg cgttatatga caacagcagt caatgtcacc 5341 cactctggaa cagaaatcgt cgacttaatg tgccatgcca ccttcacttc acgtctacta 5401 cagccaatca gagtccccaa ctataatctg tacattatgg atgaggccca cttcacagat 5461 ccctcaagta tagcagcaag aggatacatt tcaacaaggg ttgagatggg cgaggcggct 5521 gccatcttca tgaccgccac gccaccagga acccgtgacg catttccgga ctccaactca 5581 ccaattatgg acaccgaagt ggaagtccca gagagagcct ggagctcagg ctttgattgg 5641 gtgacggatc attctggaaa aacagtttgg tttgttccaa gcgtgaggaa cggcaatgag 5701 atcgcagctt gtctgacaaa ggctggaaaa cgggtcatac agctcagcag aaagactttt 5761 gagacagagt tccagaaaac aaaacatcaa gagtgggact ttgtcgtgac aactgacatt 5821 tcagagatgg gcgccaactt taaagctgac cgtgtcatag attccaggag atgcctaaag 5881 ccggtcatac ttgatggcga gagagtcatt ctggctggac ccatgcctgt cacacatgcc 5941 agcgctgccc agaggagggg gcgcataggc aggaatccca ataaacctgg agatgagtat 6001 ctgtatggag gtgggtgcgc agagactgac gaagaccatg cacactggct tgaagcaaga 6061 atgctccttg acaatattta cctccaagat ggcctcatag cctcgctcta tcgacctgag 6121 gccgacaaag tagcagccat tgagggagag ttcaagctta ggacggagca aaggaagacc 6181 tttgtggaac tcatgaaaag aggagatctt cctgtttggc tggcctatca ggttgcatct 6241 gccggaataa cctacacaga tagaagatgg tgctttgatg gcacgaccaa caacaccata 6301 atggaagaca gtgtgccggc agaggtgtgg accagacacg gagagaaaag agtgctcaaa 6361 ccgaggtgga tggacgccag agtttgttca gatcatgcgg ccctgaagtc attcaaggag 6421 tttgccgctg ggaaaagagg agcggctttt ggagtgatgg aagccctggg aacactgcca 6481 ggacacatga cagagagatt ccaggaagcc attgacaacc tcgctgtgct catgcgggca 6541 gagactggaa gcaggcctta caaagccgcg gcggcccaat tgccggagac cctagagacc 6601 attatgcttt tggggctgct gggaacagtc tcgctgggaa tctttttcgt cttgatgagg 6661 aacaagggca tagggaagat gggctttgga atggtgactc ttggggccag cgcatggctc 6721 atgtggctct cggaaattga gccagccaga attgcatgtg tcctcattgt tgtgttccta 6781 ttgctggtgg tgctcatacc tgagccagaa aagcaaagat ctccccagga caaccaaatg 6841 gcaatcatca tcatggtagc agtaggtctt ctgggcttga ttaccgccaa tgaactcgga 6901 tggttggaga gaacaaagag tgacctaagc catctaatgg gaaggagaga ggagggggca 6961 accataggat tctcaatgga cattgacctg cggccagcct cagcttgggc catctatgct 7021 gccttgacaa ctttcattac cccagccgtc caacatgcag tgaccacttc atacaacaac 7081 tactccttaa tggcgatggc cacgcaagct ggagtgttgt ttggtatggg caaagggatg 7141 ccattctacg catgggactt tggagtcccg ctgctaatga taggttgcta ctcacaatta 7201 acacccctga ccctaatagt ggccatcatt ttgctcgtgg cgcactacat gtacttgatc 7261 ccagggctgc aggcagcagc tgcgcgtgct gcccagaaga gaacggcagc tggcatcatg 7321 aagaaccctg ttgtggatgg aatagtggtg actgacattg acacaatgac aattgacccc 7381 caagtggaga aaaagatggg acaggtgcta ctcatagcag tagccgtctc cagcgccata 7441 ctgtcgcgga ccgcctgggg gtggggggag gccggggccc tgatcacagc cgcaacttcc 7501 actttgtggg aaggctctcc gaacaagtac tggaactcct ctacagccac ttcactgtgt 7561 aacattttta ggggaagtta cttggctgga gcttctctaa tctacacagt aacaagaaac 7621 gctggcttgg tcaagagacg agggggtgga acaggagaga ccctgggaga gaaatggaag 7681 gcccgcttga accagatgtc ggccctggag ttctactcct acaaaaagtc aggcatcacc 7741 gaggtgtgca gagaagaggc ccgccgcgcc ctcaaggacg gtgtggcaac gggaggccat 7801 gctgtgtccc gaggaagtgc aaagctgaga tggttggtgg agcggggata cctgcagccc 7861 tatggaaagg tcattgatct tggatgtggc agagggggct ggagttacta cgccgccacc 7921 atccgcaaag ttcaagaagt gaaaggatac acaaaaggag gccctggtca tgaagaaccc 7981 gtgttggtgc aaagctatgg gtggaacata gtccgtctta agagtggggt ggacgtcttt 8041 catatggcgg ctgagccgtg tgacacgttg ctgtgtgaca taggtgagtc atcatctagt 8101 cctgaagtgg aagaagcacg gacgctcaga gtcctctcca tggtggggga ttggcttgaa 8161 aaaagaccag gagccttttg tataaaagtg ttgtgcccat acaccagcac tatgatggaa 8221 accctggagc gactgcagcg taggtatggg ggaggactgg tcagagtgcc actctcccgc 8281 aactctacac atgagatgta ctgggtctct ggagcgaaaa gcaacaccat aaaaagtgtg 8341 tccaccacga gccagctcct cttggggcgc atggacgggc ctaggaggcc agtgaaatat 8401 gaggaggatg tgaatctcgg ctctggcacg cgggctgtgg taagctgcgc tgaagctccc 8461 aacatgaaga tcattggtaa ccgcattgaa aggatccgca gtgagcacgc ggaaacgtgg 8521 ttctttgacg agaaccaccc atataggaca tgggcttacc atggaagcta tgaggccccc 8581 acacaagggt cagcgtcctc tctaataaac ggggttgtca ggctcctgtc aaaaccctgg 8641 gatgtggtga ctggagtcac aggaatagcc atgaccgaca ccacaccgta tggtcagcaa 8701 agagttttca aggaaaaagt ggacactagg gtgccagacc cccaagaagg cactcgtcag 8761 gttatgagca tggtctcttc ctggttgtgg aaagagctag gcaaacacaa acggccacga 8821 gtctgtacca aagaagagtt catcaacaag gttcgtagca atgcagcatt aggggcaata 8881 tttgaagagg aaaaagagtg gaagactgca gtggaagctg tgaacgatcc aaggttctgg 8941 gctctagtgg acaaggaaag agagcaccac ctgagaggag agtgccagag ttgtgtgtac 9001 aacatgatgg gaaaaagaga aaagaaacaa ggggaatttg gaaaggccaa gggcagccgc 9061 gccatctggt atatgtggct aggggctaga tttctagagt tcgaagccct tggattcttg 9121 aacgaggatc actggatggg gagagagaac tcaggaggtg gtgttgaagg gctgggatta 9181 caaagactcg gatatgtcct agaagagatg agtcgcatac caggaggaag gatgtatgca 9241 gatgacactg ctggctggga cacccgcatt agcaggttcg atctggagaa tgaagctcta 9301 atcaccaacc aaatggagaa agggcacagg gccttggcat tggccataat caagtacaca 9361 taccaaaaca aagtggtaaa ggtccttaga ccagctgaaa aagggaaaac agttatggac 9421 attatttcga gacaagacca aagggggagc ggacaagttg tcacttacgc tcttaacaca 9481 tttaccaacc tagtggtgca actcattcgg aatatggagg ctgaggaagt tctggagatg 9541 caagacttgt ggctgctgcg gaggtcagag aaagtgacca actggttgca gagcaacgga 9601 tgggataggc tcaaacgaat ggcagtcagt ggagatgact gcgttgtgaa gccaattgat 9661 gataggtttg cacatgccct caggttcttg aatgatatgg gaaaagttag gaaggacaca 9721 caagagtgga aaccctcaac tggatgggac aactgggaag aagttccgtt ttgctcccac 9781 cacttcaaca agctccatct caaggacggg aggtccattg tggttccctg ccgccaccaa 9841 gatgaactga ttggccgggc ccgcgtctct ccaggggcgg gatggagcat ccgggagact 9901 gcttgcctag caaaatcata tgcgcaaatg tggcagctcc tttatttcca cagaagggac 9961 ctccgactga tggccaatgc catttgttca tctgtgccag ttgactgggt tccaactggg 10021 agaactacct ggtcaatcca tggaaaggga gaatggatga ccactgaaga catgcttgtg 10081 gtgtggaaca gagtgtggat tgaggagaac gaccacatgg aagacaagac cccagttgcg 10141 aaatggacag acattcccta tttgggaaaa agggaagact tgtggtgtgg atctctcata 10201 gggcacagac cgcgcaccac ctgggctgag aacattaaaa acacagtcaa catggtgcgc 10261 aggatcatag gtgatgaaga aaagtacatg gactacctat ccacccaagt tcgctacttg 10321 ggtgaagaag ggtctacacc tggagtgctg taagcaccaa tcttaatgtt gtcaggcctg 10381 ctagtcagcc a

Sequences producing significant alignments: Select:AllNone Selected:0 AlignmentsDownloadGenBankGraphicsDistance tree of resultsShow/hide columns of the table presenting sequences producing significant alignments Sequences producing significant alignments: Select for downloading or viewing reports Description Max score Total score Query cover E value Ident Accession Select seq gb|KY317937.1| Zika virus isolate ZIKV/Homo_sapiens/Colombia/2016/ZC192Se polyprotein gene, complete cds 18969 18969 100% 0.0 100% KY317937.1 Select seq gb|KU647676.1| Zika virus strain MRS_OPY_Martinique_PaRi_2015 polyprotein gene, complete cds 18897 18897 100% 0.0 99% KU647676.1 Select seq gb|KY317938.1| Zika virus isolate ZIKV/Homo_sapiens/Colombia/2016/ZC199Se polyprotein gene, complete cds 18881 18881 100% 0.0 99% KY317938.1 Select seq gb|KY014303.1| Zika virus isolate Zika virus/H.sapiens-wt/DOM/2016/BB-0127-SER polyprotein gene, complete cds 18875 18875 100% 0.0 99% KY014303.1 Select seq gb|KU922960.1| Zika virus isolate MEX/InDRE/Sm/2016, complete genome 18875 18875 100% 0.0 99% KU922960.1 Select seq gb|KX198135.2| Zika virus strain ZIKV/Homo sapiens/PAN/BEI-259634_V4/2016, complete genome 18870 18870 100% 0.0 99% KX198135.2 Select seq gb|KU922923.1| Zika virus isolate MEX/InDRE/Lm/2016, complete genome 18870 18870 100% 0.0 99% KU922923.1 Select seq gb|KY317939.1| Zika virus isolate ZIKV/Homo_sapiens/Colombia/2016/ZC204Se polyprotein gene, complete cds 18866 18866 100% 0.0 99% KY317939.1 Select seq gb|KX156776.2| Zika virus strain ZIKV/Homo sapiens/PAN/CDC-259364_V1-V2/2015, complete genome 18859 18859 100% 0.0 99% KX156776.2 Select seq gb|KY317936.1| Zika virus isolate ZIKV/Homo_sapiens/Colombia/2016/ZC188Se polyprotein gene, complete cds 18853 18853 100% 0.0 99% KY317936.1 Select seq gb|KX156774.2| Zika virus strain ZIKV/Homo sapiens/PAN/CDC-259359_V1-V3/2015, complete genome 18853 18853 100% 0.0 99% KX156774.2 Select seq gb|KY317940.1| Zika virus isolate ZIKV/Homo_sapiens/Colombia/2016/ZC207Se polyprotein gene, complete cds 18848 18848 100% 0.0 99% KY317940.1 Select seq gb|KX156775.2| Zika virus strain ZIKV/Homo sapiens/PAN/CDC-259249_V1-V3/2015, complete genome 18848 18848 100% 0.0 99% KX156775.2 Select seq gb|KX087102.2| Zika virus strain ZIKV/Homo sapiens/COL/FLR/2015, complete genome 18848 18848 100% 0.0 99% KX087102.2 Select seq gb|KU820897.5| Zika virus isolate FLR polyprotein gene, complete cds 18848 18848 100% 0.0 99% KU820897.5 Select seq gb|KX548902.1| Zika virus isolate ZIKV/COL/FCC00093/2015 polyprotein gene, complete cds 18848 18848 100% 0.0 99% KX548902.1 Select seq gb|KX247646.1| Zika virus isolate Zika virus/Homo sapiens/COL/UF-1/2016, complete genome 18848 18848 100% 0.0 99% KX247646.1 Select seq gb|KY075932.1| Zika virus isolate ZIKV/Homo_sapiens/USA/2016/FL001Sa polyprotein gene, complete cds 18825 18825 100% 0.0 99% KY075932.1 Select seq gb|KX893855.1| Zika virus strain Zika virus/Homo sapiens/VEN/UF-2/2016, complete genome 18818 18818 100% 0.0 99% KX893855.1 Select seq gb|KX702400.1| Zika virus strain Zika virus/Homo sapiens/VEN/UF-1/2016, complete genome 18814 18814 100% 0.0 99% KX702400.1 Select seq gb|KX447510.1| Zika virus isolate 1_0049_PF polyprotein gene, complete cds 18814 18814 100% 0.0 99% KX447510.1 Select seq gb|KU991811.1| Zika virus isolate Brazil/2016/INMI1 polyprotein gene, complete cds 18809 18809 100% 0.0 99% KU991811.1 Select seq gb|KX447512.1| Zika virus isolate 1_0181_PF polyprotein gene, complete cds 18803 18803 100% 0.0 99% KX447512.1 Select seq gb|KX369547.1| Zika virus strain PF13/251013-18, complete genome 18803 18803 100% 0.0 99% KX369547.1 Select seq gb|KU509998.3| Zika virus strain Haiti/1225/2014, complete genome 18803 18803 100% 0.0 99% KU509998.3 Select seq gb|KJ776791.2| Zika virus strain H/PF/2013, complete genome 18798 18798 100% 0.0 99% KJ776791.2 Select seq gb|KX447509.1| Zika virus isolate 1_0087_PF polyprotein gene, complete cds 18798 18798 100% 0.0 99% KX447509.1 Select seq gb|KX447513.1| Zika virus isolate 1_0134_PF polyprotein gene, complete cds 18792 18792 100% 0.0 99% KX447513.1 Select seq gb|KR872956.1| Zika virus strain 17829 polyprotein gene, complete cds 18787 18787 100% 0.0 99% KR872956.1 Select seq gb|KX197205.1| Zika virus isolate 9, complete genome 18787 18787 100% 0.0 99% KX197205.1 Select seq gb|KX447515.1| Zika virus isolate 1_0030_PF polyprotein gene, complete cds 18787 18787 100% 0.0 99% KX447515.1 Select seq gb|KX447511.1| Zika virus isolate 1_0015_PF polyprotein gene, complete cds 18787 18787 100% 0.0 99% KX447511.1 Select seq gb|KX280026.1| Zika virus isolate Paraiba_01, complete genome 18787 18787 100% 0.0 99% KX280026.1 Select seq gb|KU321639.1| Zika virus strain ZikaSPH2015, complete genome 18787 18787 100% 0.0 99% KU321639.1 Select seq gb|KX447514.1| Zika virus isolate 1_0035_PF polyprotein gene, complete cds 18781 18781 100% 0.0 99% KX447514.1 Select seq gb|KX051563.1| Zika virus isolate Haiti/1/2016, complete genome 18781 18781 100% 0.0 99% KX051563.1 Select seq gb|KX447516.1| Zika virus isolate 1_0111_PF polyprotein gene, complete cds 18776 18776 100% 0.0 99% KX447516.1 Select seq gb|KU729218.1| Zika virus isolate BeH828305 polyprotein gene, complete cds 18776 18776 100% 0.0 99% KU729218.1 Select seq gb|KU707826.1| Zika virus isolate SSABR1, complete genome 18776 18776 100% 0.0 99% KU707826.1 Select seq gb|KU365779.1| Zika virus strain BeH819966 polyprotein gene, complete cds 18776 18776 100% 0.0 99% KU365779.1 Select seq gb|KX262887.1| Zika virus isolate 103451, complete genome 18770 18770 100% 0.0 99% KX262887.1 Select seq gb|KX197192.1| Zika virus isolate ZIKV/H.sapiens/Brazil/PE243/2015, complete genome 18770 18770 100% 0.0 99% KX197192.1 Select seq gb|KU497555.1| Zika virus isolate Brazil-ZKV2015, complete genome 18766 18766 99% 0.0 99% KU497555.1 Select seq gb|KX811222.1| Zika virus isolate Brazil_2015_MG, complete genome 18764 18764 100% 0.0 99% KX811222.1 Select seq gb|KX694534.2| Zika virus strain ZIKV/Homo sapiens/HND/R103451/2015, complete genome 18759 18759 100% 0.0 99% KX694534.2 Select seq gb|KX879604.1| Zika virus isolate SN089, complete genome 18759 18759 100% 0.0 99% KX879604.1 Select seq gb|KU926309.1| Zika virus isolate Rio-U1, complete genome 18759 18759 100% 0.0 99% KU926309.1 Select seq gb|KU365780.1| Zika virus strain BeH815744 polyprotein gene, complete cds 18759 18759 100% 0.0 99% KU365780.1 Select seq gb|KU940228.1| Zika virus isolate Bahia07, partial genome 18753 18753 100% 0.0 99% KU940228.1 Select seq gb|KU365777.1| Zika virus strain BeH818995 polyprotein gene, complete cds 18753 18753 100% 0.0 99% KU365777.1 Select seq gb|KY328289.1| Zika virus isolate HN16, complete genome 18748 18748 100% 0.0 99% KY328289.1 Select seq gb|KX879603.1| Zika virus isolate SN062, complete genome 18748 18748 100% 0.0 99% KX879603.1 Select seq gb|KU758877.1| Zika virus isolate 17271 polyprotein gene, complete cds 18748 18748 100% 0.0 99% KU758877.1 Select seq gb|KU501217.1| Zika virus strain 8375 polyprotein gene, complete cds 18748 18748 100% 0.0 99% KU501217.1 Select seq gb|KY014297.1| Zika virus isolate Zika virus/H.sapiens-wt/BRA/2016/FC-6864-URI polyprotein gene, complete cds 18746 18746 100% 0.0 99% KY014297.1 Select seq gb|KU729217.2| Zika virus isolate BeH823339 polyprotein gene, complete cds 18742 18742 100% 0.0 99% KU729217.2 Select seq gb|KU527068.1| Zika virus strain Natal RGN, complete genome 18742 18742 100% 0.0 99% KU527068.1 Select seq gb|KU501216.1| Zika virus strain 103344 polyprotein gene, complete cds 18742 18742 100% 0.0 99% KU501216.1 Select seq gb|KY014327.1| Zika virus isolate Zika virus/H.sapiens-wt/HND/2016/HU-ME167-PLA polyprotein gene, complete cds 18739 18739 100% 0.0 99% KY014327.1 Select seq gb|KY120348.1| Zika virus isolate CIENI551, complete genome 18737 18737 100% 0.0 99% KY120348.1 Select seq gb|KX447517.1| Zika virus isolate 1_0038_PF polyprotein gene, complete cds 18737 18737 100% 0.0 99% KX447517.1 Select seq gb|KX247632.1| Zika virus isolate MEX_I_7 polyprotein gene, complete cds 18737 18737 100% 0.0 99% KX247632.1 Select seq gb|KU365778.1| Zika virus strain BeH819015 polyprotein gene, complete cds 18737 18737 100% 0.0 99% KU365778.1 Select seq gb|KU312312.1| Zika virus isolate Z1106033 polyprotein gene, complete cds 18737 18737 100% 0.0 99% KU312312.1 Select seq gb|KX269878.1| Zika virus isolate Haiti/2016/PD, complete genome 18733 18733 100% 0.0 99% KX269878.1 Select seq gb|KY014315.1| Zika virus isolate Zika virus/H.sapiens-wt/HND/2016/HU-ME152-SER polyprotein gene, complete cds 18731 18731 100% 0.0 99% KY014315.1 Select seq gb|KY014304.1| Zika virus isolate Zika virus/H.sapiens-wt/DOM/2016/BB-0180-SER polyprotein gene, complete cds 18731 18731 100% 0.0 99% KY014304.1 Select seq gb|KX520666.1| Zika virus isolate HS-2015-BA-01 polyprotein gene, complete cds 18731 18731 100% 0.0 99% KX520666.1 Select seq gb|KU870645.1| Zika virus isolate FB-GWUH-2016, complete genome 18731 18731 100% 0.0 99% KU870645.1 Select seq gb|KX446951.2| Zika virus strain ZIKV/Aedes.sp/MEX/MEX_I-7/2016, complete genome 18726 18726 100% 0.0 99% KX446951.2 Select seq gb|KY014296.1| Zika virus isolate Zika virus/H.sapiens-wt/BRA/2016/FC-DQ131D1-URI polyprotein gene, complete cds 18726 18726 100% 0.0 99% KY014296.1 Select seq gb|KX806557.2| Zika virus isolate TS17-2016, complete genome 18726 18726 100% 0.0 99% KX806557.2 Select seq gb|KX856011.1| Zika virus strain ZIKV/Aedes sp./MEX_I-44/2016, complete genome 18726 18726 100% 0.0 99% KX856011.1 Select seq gb|KU937936.1| Zika virus isolate ZIKVNL00013 polyprotein gene, complete cds 18726 18726 100% 0.0 99% KU937936.1 Select seq gb|KU926310.1| Zika virus isolate Rio-S1, complete genome 18726 18726 100% 0.0 99% KU926310.1 Select seq gb|KU501215.1| Zika virus strain PRVABC59, complete genome 18726 18726 100% 0.0 99% KU501215.1 Select seq gb|KX446950.2| Zika virus strain ZIKV/Aedes.sp/MEX/MEX_2-81/2016, complete genome 18720 18720 100% 0.0 99% KX446950.2 Select seq gb|KX087101.3| Zika virus strain ZIKV/Homo sapiens/PRI/PRVABC59/2015, complete genome 18720 18720 100% 0.0 99% KX087101.3 Select seq gb|KX601168.1| Zika virus strain ZIKV/Homo Sapiens/PRI/PRVABC59/2015, complete genome 18720 18720 100% 0.0 99% KX601168.1 Select seq gb|KY003153.1| Zika virus strain ZIKV/34997/Pavia/2016 polyprotein gene, complete cds 18715 18715 100% 0.0 99% KY003153.1 Select seq gb|KX377337.1| Zika virus strain PRVABC-59, complete genome 18715 18715 100% 0.0 99% KX377337.1 Select seq gb|KU820898.1| Zika virus isolate GZ01 polyprotein gene, complete cds 18715 18715 100% 0.0 99% KU820898.1 Select seq gb|KU853013.1| Zika virus isolate Dominican Republic/2016/PD2, complete genome 18715 18715 100% 0.0 99% KU853013.1 Select seq gb|KU853012.1| Zika virus isolate Dominican Republic/2016/PD1, complete genome 18713 18713 100% 0.0 99% KU853012.1 Select seq gb|KY014300.1| Zika virus isolate Zika virus/H.sapiens-wt/DOM/2016/BB-0208-SER polyprotein gene, complete cds 18709 18709 100% 0.0 99% KY014300.1 Select seq dbj|LC190723.1| Zika virus genomic RNA, complete genome, strain: ZIKV/Hu/Yokohama/1/2016 18709 18709 100% 0.0 99% LC190723.1 Select seq gb|KY075939.1| Zika virus isolate ZIKV/Aedes_aegypti/USA/2016/FL08M polyprotein gene, complete cds 18703 18703 100% 0.0 99% KY075939.1 Select seq gb|KY075933.1| Zika virus isolate ZIKV/Homo_sapiens/USA/2016/FL008U polyprotein gene, complete cds 18703 18703 100% 0.0 99% KY075933.1 Select seq gb|KY014321.1| Zika virus isolate Zika virus/H.sapiens-wt/DOM/2016/BB-0115-SER polyprotein gene, complete cds 18703 18703 100% 0.0 99% KY014321.1 Select seq gb|KY075934.1| Zika virus isolate ZIKV/Homo_sapiens/USA/2016/FL016U polyprotein gene, complete cds 18698 18698 100% 0.0 99% KY075934.1 Select seq gb|KY014295.1| Zika virus isolate Zika virus/H.sapiens-wt/USA/2016/FL-010-URI polyprotein gene, complete cds 18698 18698 100% 0.0 99% KY014295.1 Select seq gb|KX842449.2| Zika virus isolate ZIKV/Homo_sapiens/USA/2016/FL010U polyprotein gene, complete cds 18698 18698 100% 0.0 99% KX842449.2 Select seq gb|KX056898.1| Zika virus isolate Zika virus/GZ02/2016 polyprotein gene, complete cds 18698 18698 100% 0.0 99% KX056898.1 Select seq gb|KU955590.1| Zika virus isolate Z16019 polyprotein gene, complete cds 18698 18698 100% 0.0 99% KU955590.1 Select seq gb|KY120349.1| Zika virus isolate CIENI551, complete genome 18694 18694 100% 0.0 99% KY120349.1 Select seq gb|KX766028.1| Zika virus isolate R114916, complete genome 18694 18694 100% 0.0 99% KX766028.1 Select seq gb|KY003154.1| Zika virus strain ZIKV/VR10599/Pavia/2016 polyprotein gene, complete cds 18692 18692 100% 0.0 99% KY003154.1 Select seq gb|KX766029.1| Zika virus isolate R116265, complete genome 18692 18692 100% 0.0 99% KX766029.1 Select seq gb|KU740184.2| Zika virus isolate GD01 polyprotein gene, complete cds 18692 18692 100% 0.0 99% KU740184.2 Select seq gb|KU761564.1| Zika virus isolate GDZ16001 polyprotein gene, complete cds 18692 18692 100% 0.0 99% KU761564.1

Zika virus isolate ZIKV/Homo_sapiens/Colombia/2016/ZC192Se polyprotein gene, complete cds GenBank: KY317937.1 FASTA Graphics Go to: LOCUS KY317937 10462 bp RNA linear VRL 27-DEC-2016 DEFINITION Zika virus isolate ZIKV/Homo_sapiens/Colombia/2016/ZC192Se polyprotein gene, complete cds. ACCESSION KY317937 VERSION KY317937.1 KEYWORDS . SOURCE Zika virus ORGANISM Zika virus Viruses; ssRNA viruses; ssRNA positive-strand viruses, no DNA stage; Flaviviridae; Flavivirus. REFERENCE 1 (bases 1 to 10462) AUTHORS Grubaugh,N., Rogers,T., Beutler,N., Fredeking,T., Gangavarupu,K., Oliveira,G., Robles-Sikisaka,R., Burton,D. and Andersen,K. TITLE Zika virus sequenced from Colombia, 2016 JOURNAL Unpublished REFERENCE 2 (bases 1 to 10462) AUTHORS Grubaugh,N., Rogers,T., Beutler,N., Fredeking,T., Gangavarupu,K., Oliveira,G., Robles-Sikisaka,R., Burton,D. and Andersen,K. TITLE Direct Submission JOURNAL Submitted (09-DEC-2016) Department of Immunology and Microbial Science, The Scripps Research Institute, 10550 North Torrey Pines Road, IMM-210, La Jolla, CA 92037, USA COMMENT ##Assembly-Data-START## Assembly Method :: NovoAlign v. V3.04 Sequencing Technology :: Illumina ##Assembly-Data-END## FEATURES Location/Qualifiers source 1..10462 /organism="Zika virus" /mol_type="genomic RNA" /isolate="ZIKV/Homo_sapiens/Colombia/2016/ZC192Se" /isolation_source="serum" /host="Homo sapiens" /db_xref="taxon:64320" /country="Colombia" /collection_date="07-Jan-2016" /collected_by="Antibody Systems Inc" CDS 81..10352 /codon_start=1 /product="polyprotein" /protein_id="APQ41783.1" /translation="MKNPKKKSGGFRIVNMLKRGVARVSPFGGLKRLPAGLLLGHGPI RMVLAILAFLRFTAIKPSLGLINRWGSVGKKEAMEIIKKFKKDLAAMLRIINARKEKK RRGAETSVGIVGLLLTTAMAAEVTRRGSAYYMYLDRNDAGEAISFPTTLGMNKCYIQI MDLGHMCDATMSYECPMLDEGVEPDDVDCWCNTTSTWVVYGTCHHKKGEARRSRRAVT LPSHSTRKLQTRSQTWLESREYTKHLIRVENWIFRNPGFALAAAAIAWLLGSSTSQKV IYLVMILLIAPAYSIRCIGVSNRDFVEGMSGGTWVDVVLEHGGCVTVMAQDKPTVDIE LVTTTVSNMAEVRSYCYEASISDMASDSRCPTQGEAYLDKQSDTQYVCKRTLVDRGWG NGCGLFGKGSLVTCAKFACSKKMTGKSIQPENLEYRIMLSVHGSQHSGMIVNDTGHET DENRAKVEITPNSPRAEATLGGFGSLGLDCEPRTGLDFSDLYYLTMNNKHWLVHKEWF HDIPLPWHAGADTGTPHWNNKEALVEFKDAHAKRQTVVVLGSQEGAVHTALAGALEAE MDGAKGRLSSGHLKCRLKMDKLRLKGVSYSLCTAAFTFTKIPAETLHGTVTVEVQYAG TDGPCKVPAQMAVDMQTLTPVGRLITANPVITESTENSKMMLELDPPFGDSYIVIGVG EKKITHHWHRSGSTIGKAFEATVRGAKRMAVLGDTAWDFGSVGGALNSLGKGIHQIFG AAFKSLFGGMSWFSQILIGTLLMWLGLNTKNGSISLMCLALGGVLIFLSTAVSADVGC SVDFSKKETRCGTGVFVYNDVEAWRDRYKYHPDSPRRLAAAVKQAWEDGICGISSVSR MENIMWRSVEGELNAILEENGVQLTVVVGSVKNPMWRGPQRLPVPVNELPHGWKAWGK SYFVRAAKTNNSFVVDGDTLKECPLKHRAWNSFLVEDHGFGVFHTSVWLKVREDYSLE CDPAVIGTAVKGKEAVHSDLGYWIESEKNDTWRLKRAHLIEMKTCEWPKSHTLWTDGI EESDLIIPKSLAGPLSHHNTREGYRTQMKGPWHSEELEIRFEECPGTKVHVEETCGTR GPSLRSTTASGRVIEEWCCRECTMPPLSFWAKDGCWYGMEIRPRKEPESNLVRSMVTA GSTDHMDHFSLGVLVILLMVQEGLKKRMTTKIIISTSMAVLVAMILGGFSMSDLAKLA ILMGATFAEMNTGGDVAHLALIAAFKVRPALLVSFIFRANWTPRESMLLALASCLLQT AISALEGDLMVLINGFALAWLAIRAMVVPRTDNITLAILAALTPLARGTLLVAWRAGL ATCGGFMLLSLKGKGSVKKNLPFVMALGLTAVRLVDPINVVGLLLLTRSGKRSWPPSE VLTAVGLICALAGGFAKADIEMAGPMAAVGLLIVSYVVSGKSVDMYIERAGDITWEKD AEVTGNSPRLDVALDESGDFSLVEDDGPPMREIILKVVLMTICGMNPIAIPFAAGAWY VYVKTGKRSGALWDVPAPKEVKKGETTDGVYRVMTRRLLGSTQVGVGVMQEGVFHTMW HVTKGSALRSGEGRLDPYWGDVKQDLVSYCGPWKLDAAWDGHSEVQLLAVPPGERARN IQTLPGIFKTKDGDIGAVALDYPAGTSGSPILDKCGRVIGLYGNGVVIKNGSYVSAIT QGRREEETPVECFEPSMLKKKQLTVLDLHPGAGKTRRVLPEIVREAIKTRLRTVILAP TRVVAAEMEEALRGLPVRYMTTAVNVTHSGTEIVDLMCHATFTSRLLQPIRVPNYNLY IMDEAHFTDPSSIAARGYISTRVEMGEAAAIFMTATPPGTRDAFPDSNSPIMDTEVEV PERAWSSGFDWVTDHSGKTVWFVPSVRNGNEIAACLTKAGKRVIQLSRKTFETEFQKT KHQEWDFVVTTDISEMGANFKADRVIDSRRCLKPVILDGERVILAGPMPVTHASAAQR RGRIGRNPNKPGDEYLYGGGCAETDEDHAHWLEARMLLDNIYLQDGLIASLYRPEADK VAAIEGEFKLRTEQRKTFVELMKRGDLPVWLAYQVASAGITYTDRRWCFDGTTNNTIM EDSVPAEVWTRHGEKRVLKPRWMDARVCSDHAALKSFKEFAAGKRGAAFGVMEALGTL PGHMTERFQEAIDNLAVLMRAETGSRPYKAAAAQLPETLETIMLLGLLGTVSLGIFFV LMRNKGIGKMGFGMVTLGASAWLMWLSEIEPARIACVLIVVFLLLVVLIPEPEKQRSP QDNQMAIIIMVAVGLLGLITANELGWLERTKSDLSHLMGRREEGATIGFSMDIDLRPA SAWAIYAALTTFITPAVQHAVTTSYNNYSLMAMATQAGVLFGMGKGMPFYAWDFGVPL LMMGCYSQLTPLTLIVAIILLVAHYMYLIPGLQAAAARAAQKRTAAGIMKNPVVDGIV VTDIDTMTIDPQVEKKMGQVLLIAVAVSSAILSRTAWGWGEAGALITAATSTLWEGSP NKYWNSSTATSLCNIFRGSYLAGASLIYTVTRNAGLVKRRGGGTGETLGEKWKARLNQ MSALEFYSYKKSGITEVCREEARRALKDGVATGGHAVSRGSAKLRWLVERGYLQPYGK VIDLGCGRGGWSYYAATIRKVQEVKGYTKGGPGHEEPVLVQSYGWNIVRLKSGVDVFH MAAEPCDTLLCDIGESSSSPEVEEARTLRVLSMVGDWLEKRPGAFCIKVLCPYTSTMM ETLERLQRRYGGGLVRVPLSRNSTHEMYWVSGAKSNTIKSVSTTSQLLLGRMDGPRRP VKYEEDVNLGSGTRAVVSCAEAPNMKIIGNRIERIRSEHAETWFFDENHPYRTWAYHG SYEAPTQGSASSLINGVVRLLSKPWDVVTGVTGIAMTDTTPYGQQRVFKEKVDTRVPD PQEGTRQVMSMVSSWLWKELGKYKRPRVCTKEEFINKVRSNAALGAIFEEEKEWKTAV EAVNDPRFWALVDKEREHHLRGECQSCVYNMMGKREKKQGEFGKAKGSRAIWYMWLGA RFLEFEALGFLNEDHWMGRENSGGGVEGLGLQRLGYVLEEMSRIPGGRMYADDTAGWD TRISRFDLENEALITNQMEKGHRALALAIIKYTYQNKVVKVLRPAEKGKTVMDIISRQ DQRGSGQVVTYALNTFTNLVVQLIRNMEAEEVLEMQDLWLLRRSEKVTNWLQSNGWDR LKRMAVSGDDCVVKPIDDRFAHALRFLNDMGKVRKDTQEWKPSTGWDNWEEVPFCSHH FNKLHLKDGRSIVVPCRHQDELIGRARVSPGAGWSIRETACLAKSYAQMWQLLYFHRR DLRLMANAICSSVPVDWVPTGRTTWSIHGKGEWMTTEDMLVVWNRVWIEENDHMEDKT PVAKWTDIPYLGKREDLWCGSLIGHRPRTTWAENIKNTVNMVRRIIGDEEKYMDYLST QVRYLGEEGSTPGVL" ORIGIN 1 cgacagttcg agtttgaagc gaaagctagc aacagtatca acaggtttta ttttggattt 61 ggaaacgaga gtttctggtc atgaaaaacc caaaaaagaa atccggagga ttccggattg 121 tcaatatgct aaaacgcgga gtagcccgtg tgagcccctt tgggggcttg aagaggctgc 181 cagccggact tctgctgggt catgggccca tcaggatggt cttggcgatt ctagcctttt 241 tgagattcac ggcaatcaag ccatcactgg gtctcatcaa tagatggggt tcagtgggga 301 aaaaagaggc tatggaaata ataaagaagt tcaagaaaga tctggctgcc atgctgagaa 361 taatcaatgc taggaaggag aagaagagac gaggcgcaga aactagtgtc ggaattgttg 421 gcctcctgct gaccacagct atggcagcgg aggtcactag acgtgggagt gcatactata 481 tgtacttgga cagaaacgat gctggggagg ccatatcttt tccaaccaca ttggggatga 541 ataagtgtta tatacagatc atggatcttg gacacatgtg tgatgccacc atgagctatg 601 aatgccctat gctggatgag ggggtggaac cagatgacgt cgattgttgg tgcaacacga 661 cgtcaacttg ggttgtgtac ggaacctgcc atcacaaaaa aggtgaagca cggagatcta 721 gaagagccgt gacgctcccc tcccattcca ctaggaagct gcaaacgcgg tcgcaaacct 781 ggttggaatc aagagaatac acaaagcact tgattagagt cgaaaattgg atattcagga 841 accctggttt cgctttagca gcagctgcca tcgcgtggct tttgggaagc tcaacgagcc 901 aaaaagtcat atacttggtc atgatactgc tgattgcccc ggcatacagc atcaggtgca 961 taggagtcag caatagggac tttgtggaag gtatgtcagg tgggacttgg gttgatgttg 1021 tcttggaaca tggaggttgt gtcaccgtaa tggcacagga caaaccgact gtcgacatag 1081 agctggttac aacaacagtc agcaacatgg cggaggtaag atcctactgc tatgaggcat 1141 caatatcaga catggcttcg gacagccgct gcccaacaca aggtgaagcc taccttgaca 1201 agcaatcaga cactcaatat gtctgcaaaa gaacgttagt ggacagaggc tggggaaatg 1261 gatgtggact ttttggcaaa gggagcctgg tgacatgcgc taagtttgca tgctccaaga 1321 aaatgaccgg gaagagcatc cagccagaga atctggagta ccggataatg ttgtcagttc 1381 atggctccca gcacagtggg atgatcgtta atgacacagg acatgaaact gatgagaata 1441 gagcgaaggt tgagataacg cccaattcac caagagccga agccaccctg gggggttttg 1501 gaagcctagg acttgattgt gaaccgagga caggccttga cttttcagat ttgtattact 1561 tgactatgaa taacaagcac tggttggttc acaaggagtg gttccacgac attccattac 1621 cttggcacgc tggggcagac accggaactc cacactggaa caacaaagaa gcactggtag 1681 agttcaagga cgcacatgcc aaaaggcaaa ctgtcgtggt tctagggagt caagaaggag 1741 cagttcacac ggcccttgct ggagctctgg aggctgagat ggatggtgca aagggaaggc 1801 tgtcctctgg ccacttgaaa tgtcgcctga aaatggataa acttagattg aagggcgtgt 1861 catactcctt gtgtaccgca gcgttcacat tcaccaagat cccggctgaa acactgcacg 1921 ggacagtcac agtggaggta cagtacgcag ggacagatgg accttgcaag gttccagctc 1981 agatggcggt ggacatgcaa actctgaccc cagttgggag gttgataacc gctaaccccg 2041 taatcactga aagcactgag aactctaaga tgatgctgga acttgatcca ccatttgggg 2101 actcttacat tgtcatagga gtcggggaga agaagatcac ccaccactgg cacaggagtg 2161 gcagcaccat tggaaaagca tttgaagcca ctgtgagagg tgccaagaga atggcagtct 2221 tgggagacac agcctgggac tttggatcag ttggaggcgc tctcaactca ttgggcaagg 2281 gcatccatca aatttttgga gcagctttca aatcattgtt tggaggaatg tcctggttct 2341 cacaaattct cattggaacg ttgctgatgt ggttgggtct gaacacaaag aatggatcta 2401 tttcccttat gtgcttggcc ttagggggag tgttgatctt cttatccaca gccgtctctg 2461 ctgatgtggg gtgctcggtg gacttctcaa agaaggagac gagatgtggt acaggggtgt 2521 tcgtctataa cgacgttgaa gcctggaggg acaggtacaa gtaccatcct gactcccccc 2581 gtagattggc agcagcagtc aagcaagcct gggaagatgg tatctgcggg atctcctctg 2641 tttcaagaat ggaaaacatc atgtggagat cagtagaagg ggagctcaac gcaatcctgg 2701 aagagaatgg agttcaactg acggtcgttg tgggatctgt aaaaaacccc atgtggagag 2761 gtccacagag attgcccgtg cctgtgaacg agctgcccca cggctggaag gcttggggga 2821 aatcgtactt cgtcagagca gcaaagacaa ataacagctt tgtcgtggat ggtgacacac 2881 tgaaggaatg cccactcaaa catagagcat ggaacagctt tcttgtggag gatcatgggt 2941 tcggggtatt tcacactagt gtctggctca aggttagaga agattattca ttagagtgtg 3001 atccagccgt tattggaaca gctgttaagg gaaaggaggc tgtacacagt gatctaggct 3061 actggattga gagtgagaag aatgacacat ggaggctgaa gagggcccat ctgatcgaga 3121 tgaaaacatg tgaatggcca aagtcccaca cattgtggac agatggaata gaagagagtg 3181 atctgatcat acccaagtct ttagctgggc cactcagcca tcacaatacc agagagggct 3241 acaggaccca aatgaaaggg ccatggcaca gtgaagagct tgaaattcgg tttgaggaat 3301 gcccaggcac taaggtccac gtggaggaaa catgtggaac aagaggacca tctctgagat 3361 caaccactgc aagcggaagg gtgatcgagg aatggtgctg cagggagtgc acaatgcccc 3421 cactgtcgtt ctgggctaaa gatggctgtt ggtatggaat ggagataagg cccaggaaag 3481 aaccagaaag caacttagta aggtcaatgg tgactgcagg atcaactgat cacatggatc 3541 acttctccct tggagtgctt gtgattctgc tcatggtgca ggaagggctg aagaagagaa 3601 tgaccacaaa gatcatcata agcacatcaa tggcagtgct ggtagctatg atcctgggag 3661 gattttcaat gagtgacctg gctaagcttg caattttgat gggtgccacc ttcgcggaaa 3721 tgaacactgg aggagatgta gctcatctgg cgctgatagc ggcattcaaa gtcagaccag 3781 cgttgctggt atctttcatc ttcagagcta attggacacc ccgtgaaagc atgctgctgg 3841 ccttggcctc gtgtcttttg caaactgcga tctctgcctt ggaaggcgac ctgatggttc 3901 tcatcaatgg ttttgctttg gcctggttgg caatacgagc gatggttgtt ccacgcactg 3961 acaacatcac cttggcaatc ctggctgctc tgacaccact ggcccggggc acactgcttg 4021 tggcgtggag agcaggcctt gctacttgcg gggggtttat gctcctctct ctgaagggaa 4081 aaggcagtgt gaagaagaac ttaccatttg tcatggccct gggactaacc gctgtgaggc 4141 tggtcgaccc catcaacgtg gtgggactgc tgttgctcac aaggagtggg aagcggagct 4201 ggccccctag cgaagtactc acagctgttg gcctgatatg cgcattggct ggagggttcg 4261 ccaaggcaga tatagagatg gctgggccca tggccgcggt cggtctgcta attgtcagtt 4321 acgtggtctc aggaaagagt gtggacatgt acattgaaag agcaggtgac atcacatggg 4381 aaaaagatgc ggaagtcact ggaaacagtc cccggctcga cgtggcgcta gatgagagtg 4441 gtgatttctc cctggtggag gatgacggtc cccccatgag agagatcata ctcaaggtgg 4501 tcctgatgac catctgtggc atgaacccaa tagccatacc ctttgcagct ggagcgtggt 4561 acgtatacgt gaagactgga aaaaggagtg gtgctctatg ggatgtgcct gctcccaagg 4621 aagtaaaaaa gggggagacc acagatggag tgtacagagt aatgactcgt agactgctag 4681 gttcaacaca agttggagtg ggagttatgc aagagggggt ctttcacact atgtggcacg 4741 tcacaaaagg atccgcgctg agaagcggtg aagggagact tgatccatac tggggagatg 4801 tcaagcagga tctggtgtca tactgtggtc catggaagct agatgccgcc tgggacggac 4861 acagcgaggt gcagctcttg gccgtgcccc ccggagagag agcgaggaac atccagactc 4921 tgcccggaat atttaagaca aaggatgggg acattggagc ggttgcgctg gattacccag 4981 caggaacttc aggatctcca atcctagaca agtgtgggag agtgatagga ctttatggca 5041 atggggtcgt gatcaaaaat gggagttatg ttagtgccat cacccaaggg aggagggagg 5101 aagagactcc tgttgagtgc ttcgagcctt cgatgctgaa gaagaagcag ctaactgtct 5161 tagacttgca tcctggagct gggaaaacca ggagagttct tcctgaaata gttcgtgaag 5221 ccataaaaac aagactccgt actgtgatct tagctccaac cagggttgtc gctgctgaaa 5281 tggaggaagc ccttagaggg cttccagtgc gttatatgac aacagcagtc aatgtcaccc 5341 actctggaac agaaatcgtc gacttaatgt gccatgccac cttcacttca cgtctactac 5401 agccaatcag agtccccaac tataatctgt atattatgga tgaggcccac ttcacagatc 5461 cctcaagtat agcagcaaga ggatacattt caacaagggt tgagatgggc gaagcggctg 5521 ccatcttcat gaccgccacg ccaccaggaa cccgtgacgc atttccggac tccaactcac 5581 caattatgga caccgaagtg gaagtcccag agagagcctg gagctcaggc tttgattggg 5641 tgacggatca ttctggaaaa acagtttggt ttgttccaag cgtgaggaac ggcaatgaga 5701 tcgcagcttg tctgacaaag gctggaaaac gggtcataca gctcagcaga aagacttttg 5761 agacagagtt ccagaaaaca aaacatcaag agtgggactt tgtcgtgaca actgacattt 5821 cagagatggg cgccaacttt aaagctgacc gtgtcataga ttccaggaga tgcctaaagc 5881 cggtcatact tgatggcgag agagtcattc tggctggacc catgcctgtc acacatgcca 5941 gcgctgccca gaggaggggg cgcataggca ggaatcccaa taaacctgga gatgagtatc 6001 tgtatggagg tgggtgcgca gagactgacg aagaccatgc acactggctt gaagcaagaa 6061 tgctccttga caatatttac ctccaagatg gcctcatagc ctcgctctat cgacctgagg 6121 ccgacaaagt agcagccatt gagggagagt tcaagcttag gacggagcaa aggaagacct 6181 ttgtggaact catgaaaaga ggagatcttc ctgtttggct ggcctatcag gttgcatctg 6241 ccggaataac ctacacagat agaagatggt gctttgatgg cacgaccaac aacaccataa 6301 tggaagacag tgtgccggca gaggtgtgga ccagacacgg agagaaaaga gtgctcaaac 6361 cgaggtggat ggacgccaga gtttgttcag atcatgcggc cctgaagtca ttcaaggagt 6421 ttgccgctgg gaaaagagga gcggcttttg gagtgatgga agccctggga acactgccag 6481 gacacatgac agagagattc caggaagcca ttgacaacct cgctgtgctc atgcgggcag 6541 agactggaag caggccttac aaagccgcgg cggcccaatt gccggagacc ctagagacca 6601 ttatgctttt ggggttgctg ggaacagtct cgctgggaat ctttttcgtc ttgatgagga 6661 acaagggcat agggaagatg ggctttggaa tggtgactct tggggccagc gcatggctca 6721 tgtggctctc ggaaattgag ccagccagaa ttgcatgtgt cctcattgtt gtgttcctat 6781 tgctggtggt gctcatacct gagccagaaa agcaaagatc tccccaggac aaccaaatgg 6841 caatcatcat catggtagca gtaggtcttc tgggcttgat taccgccaat gaactcggat 6901 ggttggagag aacaaagagt gacctaagcc atctaatggg aaggagagag gagggggcaa 6961 ccataggatt ctcaatggac attgacctgc ggccagcctc agcttgggcc atctatgctg 7021 ccttgacaac tttcattacc ccagccgtcc aacatgcagt gaccacttca tacaacaact 7081 actccttaat ggcgatggcc acgcaagctg gagtgttgtt tggtatgggc aaagggatgc 7141 cattctacgc atgggacttt ggagtcccgc tgctaatgat gggttgctac tcacaattaa 7201 cacccctgac cctaatagtg gccatcattt tgctcgtggc gcactacatg tacttgatcc 7261 cagggctgca ggcagcagct gcgcgtgctg cccagaagag aacggcagct ggcatcatga 7321 agaaccctgt tgtggatgga atagtggtga ctgacattga cacaatgaca attgaccccc 7381 aagtggagaa aaagatggga caggtgctac tcatagcagt agccgtctcc agcgccatac 7441 tgtcgcggac cgcctggggg tggggggagg ctggggccct gatcacagcc gcaacttcca 7501 ctttgtggga aggctctccg aacaagtact ggaactcctc tacagccact tcactgtgta 7561 acatttttag gggaagttac ttggctggag cttctctaat ctacacagta acaagaaacg 7621 ctggcttggt caagagacgt gggggtggaa caggagagac cctgggagag aaatggaagg 7681 cccgtttgaa ccagatgtcg gccctggagt tctactccta caaaaagtca ggcatcaccg 7741 aggtgtgcag agaagaggct cgccgcgccc tcaaggacgg tgtggcaacg ggaggccatg 7801 ctgtgtcccg aggaagtgca aagctgagat ggttggtgga gcggggatac ctgcagccct 7861 atggaaaggt cattgatctt ggatgtggca gagggggctg gagttactac gccgccacca 7921 tccgcaaagt tcaagaagtg aaaggataca caaaaggagg ccctggtcat gaagaacccg 7981 tgttggtgca aagctatggg tggaacatag tccgtcttaa gagtggggtg gacgtctttc 8041 atatggcggc tgagccgtgt gacacgttgc tgtgtgacat aggtgagtca tcatctagtc 8101 ctgaagtgga agaagcacgg acgctcagag tcctctccat ggtgggggat tggcttgaaa 8161 aaagaccagg agccttttgt ataaaagtgt tgtgcccata caccagcact atgatggaaa 8221 ccctggagcg actgcagcgt aggtatgggg gaggactggt cagagtgcca ctctcccgca 8281 actctacaca tgagatgtac tgggtctctg gagcgaaaag caacaccata aaaagtgtgt 8341 ccaccacgag ccagctcctc ttggggcgca tggacgggcc taggaggcca gtgaaatatg 8401 aggaggatgt gaatctcggc tctggcacgc gggctgtggt aagctgcgct gaagctccca 8461 acatgaagat cattggtaac cgcattgaaa ggatccgcag tgagcacgcg gaaacgtggt 8521 tctttgatga gaaccaccca tataggacat gggcttacca tggaagctat gaggccccca 8581 cacaagggtc agcgtcctct ctaataaacg gggttgtcag gctcctgtca aaaccctggg 8641 atgtggtgac tggagtcaca ggaatagcca tgaccgacac cacaccgtat ggtcagcaaa 8701 gagttttcaa ggaaaaagtg gacactaggg tgccagaccc ccaagaaggc actcgtcagg 8761 ttatgagcat ggtctcttcc tggttgtgga aagagctagg caaatacaaa cggccacgag 8821 tctgtaccaa agaagagttc atcaacaagg ttcgtagcaa tgcagcatta ggggcaatat 8881 ttgaagagga aaaagagtgg aagactgcag tggaagctgt gaacgatcca aggttctggg 8941 ctctagtgga caaggaaaga gagcaccacc tgagaggaga gtgccagagt tgtgtgtaca 9001 acatgatggg aaaaagagaa aagaaacaag gggaatttgg aaaggccaag ggcagccgcg 9061 ccatctggta tatgtggcta ggggctagat ttctagagtt cgaagccctt ggattcttga 9121 acgaggatca ctggatgggg agagagaact caggaggtgg tgttgaaggg ctgggattac 9181 aaagactcgg atatgtccta gaagagatga gtcgcatacc aggaggaagg atgtatgcag 9241 atgacactgc tggctgggac acccgcatca gcaggtttga tctggagaat gaagctctaa 9301 tcaccaacca aatggagaaa gggcacaggg ccttggcatt ggccataatc aagtacacat 9361 accaaaacaa agtggtaaag gtccttagac cagctgaaaa agggaaaaca gttatggaca 9421 ttatttcgag acaagaccaa agggggagcg gacaagttgt cacttacgct cttaacacat 9481 ttaccaacct agtggtgcaa ctcattcgga atatggaggc tgaggaagtt ctagagatgc 9541 aagacttgtg gctgctgcgg aggtcagaga aagtgaccaa ctggttgcag agcaacggat 9601 gggataggct caaacgaatg gcagtcagtg gagatgattg cgttgtgaag ccaattgatg 9661 ataggtttgc acatgccctc aggttcttga atgatatggg aaaagttagg aaggacacac 9721 aagagtggaa accctcaact ggatgggaca actgggaaga agttccgttt tgctcccacc 9781 acttcaacaa gctccatctc aaggacggga ggtccattgt ggttccctgc cgccaccaag 9841 atgaactgat tggccgggcc cgcgtctctc caggggcggg atggagcatc cgggagactg 9901 cttgcctagc aaaatcatat gcgcaaatgt ggcagctcct ttatttccac agaagggacc 9961 tccgactgat ggccaatgcc atttgttcat ctgtgccagt tgactgggtt ccaactggga 10021 gaactacctg gtcaatccat ggaaagggag aatggatgac cactgaagac atgcttgtgg 10081 tgtggaacag agtgtggatt gaggagaacg accacatgga agacaagacc ccagttgcga 10141 aatggacaga cattccctat ttgggaaaaa gggaagactt gtggtgtgga tctctcatag 10201 ggcacagacc gcgcaccacc tgggctgaga acattaaaaa cacagtcaac atggtgcgca 10261 ggatcatagg tgatgaagaa aagtacatgg actacctatc cacccaagtt cgctacttgg 10321 gtgaagaagg gtctacacct ggagtgctgt aagcaccaat cttaatgttg tcaggcctgc 10381 tagtcagcca cagcttgggg aaagctgtgc agcctgtgac ccccccagga gaagctggga 10441 aaccaagcct atagtcaggc cg

As of December 28, 2016 (5 am EST) Zika virus disease and Zika virus congenital infection are nationally notifiable conditions. This update from the CDC Arboviral Disease Branch includes provisional data reported to ArboNET for January 01, 2015 – December 28, 2016. US States Locally acquired mosquito-borne cases reported: 216 Travel-associated cases reported: 4,592 Laboratory acquired cases reported: 1 Total: 4,809 Sexually transmitted: 38 Guillain-Barré syndrome: 13 MAPS OF ZIKA IN THE US More US Territories Locally acquired cases reported: 34,841 Travel-associated cases reported: 132 Total: 34,973* Guillain-Barré syndrome: 50 *Sexually transmitted cases are not reported for US territories because with local transmission of Zika virus it is not possible to determine whether infection occurred due to mosquito-borne or sexual transmission. Laboratory-confirmed Zika virus disease cases reported to ArboNET by state or territory — United States, 2015–2016 (as of December 28, 2016)§ States Travel-associated cases* No. (% of cases in states) (N=4,593) Locally acquired cases† No. (% of cases in states) (N=216) Alabama 30 (1) 0 (0) Arizona 51 (1) 0 (0) Arkansas 15 (<1) 0 (0) California 389 (9) 0 (0) Colorado 53 (1) 0 (0) Connecticut 58 (1) 0 (0) Delaware 17 (<1) 0 (0) District of Columbia 28 (1) 0 (0) Florida 825 (18) 210 (98) Georgia 106 (2) 0 (0) Hawaii 16 (<1) 0 (0) Idaho 4 (<1) 0 (0) Illinois 88 (2) 0 (0) Indiana 49 (1) 0 (0) Iowa 21 (<1) 0 (0) Kansas 19 (<1) 0 (0) Kentucky 24 (1) 0 (0) Louisiana 35 (1) 0 (0) Maine 13 (<1) 0 (0) Maryland 126 (3) 0 (0) Massachusetts 114 (2) 0 (0) Michigan 64 (1) 0 (0) Minnesota 64 (1) 0 (0) Mississippi 23 (1) 0 (0) Missouri 35 (1) 0 (0) Montana 7 (<1) 0 (0) Nebraska 13 (<1) 0 (0) Nevada 18 (<1) 0 (0) New Hampshire 12 (<1) 0 (0) New Jersey 177 (4) 0 (0) New Mexico 9 (<1) 0 (0) New York 983 (21) 0 (0) North Carolina 85 (2) 0 (0) North Dakota 2 (<1) 0 (0) Ohio 80 (2) 0 (0) Oklahoma 29 (1) 0 (0) Oregon 42 (1) 0 (0) Pennsylvania†† 166 (4) 0 (0) Rhode Island 50 (1) 0 (0) South Carolina 54 (1) 0 (0) South Dakota 2 (<1) 0 (0) Tennessee 59 (1) 0 (0) Texas 283 (6) 6 (2) Utah 20** (<1) 0 (0) Vermont 10 (<1) 0 (0) Virginia 103 (2) 0 (0) Washington 61 (1) 0 (0) West Virginia 11 (<1) 0 (0) Wisconsin 48 (1) 0 (0) Wyoming 2 (<1) 0 (0) Territories Travel-associated cases* No. (% of cases in territories) (N=132) Locally acquired cases† No. (% of cases in territories) (N=34,841) American Samoa 1 (1) 114 (<1) Puerto Rico 129 (98) 33,865*** (97) US Virgin Islands 2 (2) 862 (3) §Only includes cases meeting the probable or confirmed CSTE case definition and does not include asymptomatic infections unless the case is a pregnant woman with a complication of pregnancy *Travelers returning from affected areas, their sexual contacts, or infants infected in utero †Presumed local mosquito-borne transmission ††One additional case acquired through laboratory transmission **Includes one case with unknown route of person-to-person transmission. ***The Puerto Rico Department of Health is retroactively reporting cases, resulting in larger than normal increases in cases in recent weeks. Page last reviewed: December 29, 2016 Page last updated: December 29, 2016

TRAVEL-RELATED ZIKA CASES BY COUNTY County Number of Cases (all travel related) Alachua 10 Bay 4 Brevard 15 Broward 166 Charlotte 2 Citrus 2 Clay 6 Collier 22 Duval 10 Escambia 4 Flagler 2 Hernando 4 Highlands 1 Hillsborough 40 Indian River 1 Lake 4 Lee 14 Leon 2 Manatee 5 Marion 3 Martin 4 Miami-Dade 320 Monroe 9 Nassau 1 Okaloosa 4 Okeechobee 1 Orange 145 Osceola 35 Palm Beach 59 Pasco 9 Pinellas 21 Polk 31 Santa Rosa 1 Sarasota 5 Seminole 24 St. Johns 4 St. Lucie 11 Volusia 12 Total cases 1013 *Note: This includes pregnant women and non-Florida residents who acquired Zika outside of Florida, but were diagnosed in Florida. Data as of Dec. 29, 2016 – 10:30 a.m. ET http://www.floridahealth.gov/diseases-and-conditions/zika-virus/index.html?utm_source=flhealthIndex

Information on Active Investigations When a local case of Zika virus is confirmed through laboratory testing, the department conducts a thorough investigation around the case to determine if additional people are infected. The department interviews and tests close contacts and community members around the case. Knowing if additional people are infected helps the department determine if there is a zone where mosquitoes are transmitting the virus. Not every case results in a designation of active transmission in an area. In some instances, a case of Zika is an isolated incident with no additional people infected. For more information on the department’s testing and investigation process, click here. paragraph break Current Number of Active Investigations: 5 Miami-Dade County: 1 open investigations Unknown: 4 open investigations. paragraph break Current Number of Closed Investigations: 47 Miami-Dade County: 39 closed investigations Palm Beach County: 6 closed investigation Broward County: 1 closed investigation Pinellas: 1 closed investigation paragraph break Sampling Activities For Active Investigations paragraph brea Miami-Dade Investigations Outside of Areas Where Active Transmission Occurred – 1 Investigations Total # of Samples Collected Positive Negative Pending Results 4 0 4 0 paragraph break Wynwood Area in Miami-Dade County – Note: This investigation is closed, but the department is providing the sampling results below for reference. Total # of Samples Collected Positive Negative Pending Results 525 33 491 0 paragraph brea Little River in Miami-Dade County (Area of Active Transmission) Note: This investigation is closed, but the department is providing the sampling results below for reference. Total # of Samples Collected Positive Negative Pending Results 118 9 109 0 paragraph brea Miami Beach in Miami-Dade County (Area of Active Transmission) Total # of Samples Collected Positive Negative Pending Results 1,067 75 992 0 Data as of Dec. 29, 2016 – 10:30 a.m. ET http://www.floridahealth.gov/diseases-and-conditions/zika-virus/index.html?utm_source=flhealthIndex

December 28, 2016 Department of Health Daily Zika Update Contact: Communications [email protected] (850) 245-4111 Tallahassee, Fla.—In an effort to keep Florida residents and visitors safe and aware about the status of the Zika virus, the department issues a Zika virus update when there is a confirmed locally acquired case of Zika. There are three new travel-related cases today with two in Polk and one in Palm Beach. Please visit our website to see the full list of travel-related cases by county. The department updates the travel-related case chart online each weekday. There are three new locally acquired cases today in Miami-Dade County. The department is investigating to determine where exposure occurred. Florida still does not have any identified areas with active Zika transmission. There are two cases in Miami-Dade County residents who had exposure overseas in an area with on-going, active transmission of Zika and exposure in Miami-Dade County so it is not possible to determine whether the case is travel-related or locally acquired. These cases have been added to the undetermined category. The total number of Zika cases reported in Florida as of today is 1,286. Infection Type Infection Count Travel-Related Infections of Zika 1,011 Locally Acquired Infections of Zika 256 Undetermined 19 Pregnant Women with Lab-Evidence of Zika 208 Note, these categories are not mutually exclusive and cannot be added together. Florida no longer has any identified areas with active Zika transmission, but we will continue to see isolated cases of local transmission so it is important for residents and visitors in Miami-Dade County to remain vigilant about mosquito bite protection. DOH continues outreach and targeted testing in Miami-Dade County and mosquito abatement and reduction activities are also taking place around the locations that are being investigated. In order to keep the public informed, the department has posted our investigation process here. One case does not mean ongoing active transmission is taking place. DOH conducts a thorough investigation by sampling close contacts and community members around each case to determine if additional people are infected. If DOH finds evidence that active transmission is occurring in an area, the media and the public will be notified. Note: asymptomatic cases are not reflected as they do not have symptom on-set dates. click image above to enlarge click image above to enlarge click image above to enlarge The department is currently conducting 5 active investigations. The department has closed 47 investigations. Information regarding the investigations can be found here. If investigations reveal additional areas of active transmission, the department will announce a defined area of concern. The department has conducted Zika virus testing for more than 11,509 people statewide. Florida currently has the capacity to test 5,042 people for active Zika virus and 6,610 for Zika antibodies. At Governor Scott’s direction, all county health departments now offer free Zika risk assessment and testing to pregnant women. The CDC advises pregnant women should consider postponing travel to Miami-Dade County. If you are pregnant and must travel or if you live or work in Miami-Dade County, protect yourself from mosquito bites by wearing insect repellent, long clothing and limiting your time outdoors. According to CDC guidance, providers should test all pregnant women who lived in, traveled to or whose partner traveled to Miami-Dade County after Aug. 1, 2016. Pregnant women in Miami-Dade County can contact their medical provider or their local county health department to be tested and receive a Zika prevention kit. Additionally, the department is working closely with the Healthy Start Coalition of Miami-Dade County to identify pregnant women in Miami-Dade County to ensure they have access to resources and information to protect themselves. CDC recommends that a pregnant woman with a history of Zika virus and her provider should consider additional ultrasounds. Pregnant women can contact their local county health department for Zika risk assessment and testing hours and information. A Zika risk assessment will be conducted by county health department staff and blood and/or urine samples may be collected and sent to labs for testing. It may take one to two weeks to receive results. Florida has been monitoring pregnant women with evidence of Zika regardless of symptoms. The total number of pregnant women who have been or are being monitored is 208. On Feb. 12, Governor Scott directed the State Surgeon General to activate a Zika Virus Information Hotline for current Florida residents and visitors, as well as anyone planning on traveling to Florida in the near future. The number for the Zika Virus Information Hotline is 1-855-622-6735. The department urges Floridians to drain standing water weekly, no matter how seemingly small. A couple drops of water in a bottle cap can be a breeding location for mosquitoes. Residents and visitors also need to use repellents when enjoying the Florida outdoors. For more information on DOH action and federal guidance, please click here. For resources and information on Zika virus, click here. About the Florida Department of Health The department, nationally accredited by the Public Health Accreditation Board, works to protect, promote, and improve the health of all people in Florida through integrated state, county and community efforts. Follow us on Twitter at @HealthyFla and on Facebook. For more information about the Florida Department of Health, please visit www.FloridaHealth.gov.

There are three new locally acquired cases today in Miami-Dade County. The department is investigating to determine where exposure occurred. Florida still does not have any identified areas with active Zika transmission. There are two cases in Miami-Dade County residents who had exposure overseas in an area with on-going, active transmission of Zika and exposure in Miami-Dade County so it is not possible to determine whether the case is travel-related or locally acquired. These cases have been added to the undetermined category. The total number of Zika cases reported in Florida as of today is 1,286. Infection Type Infection Count Travel-Related Infections of Zika 1,011 Locally Acquired Infections of Zika 256 Undetermined 19 Pregnant Women with Lab-Evidence of Zika 208 http://www.floridahealth.gov/diseases-and-conditions/zika-virus/index.html?utm_source=flhealthIndex